Environmental, lifestyle, and clinical risk factor of multimorbidity development
Supervisors:
Dr Frederick Ho, School of Health & Wellbeing (University of Glasgow)
Dr Bhautesh Jani, School of Health & Wellbeing (University of Glasgow)
Prof Frances Mair, School of Health & Wellbeing (University of Glasgow)
Summary:
Multimorbidity is complex and heterogenous and there is no conclusive evidence on which risk factors at what level would be more effective in preventing multimorbidity. This project aims to address this through a series of work including evidence synthesis and primary data analyses.
A systematic review will be conducted to summarise the concurrent evidence base which will be used to inform data analyses. UK Biobank data will be used to examine the relative importance of environmental, lifestyle, and clinical risk factors for concurrent and incident multimorbidity, and any difference by types of multimorbidity. These will then be used to construct a model to disentangle the upper and lower stream mechanisms of multimorbidity as well as any interactions in between.
A Student who completes this project is expected to gain substantial understanding on the epidemiology multimorbidity, advanced epidemiological and statistical techniques, and experience of written and oral academic presentations.