2021

Guan, D., Zhuan, X., Holmes, W. , Luo, X. and Gao, H. (2021) Modelling of fibre dispersion and its effects on cardiac mechanics from diastole to systole. Journal of Engineering Mathematics, 128, 1. (doi: 10.1007/s10665-021-10102-w)

Al-Mubarak, H. F.I., Vallatos, A. and Holmes, W. M. (2021) Impact of turbulence-induced asymmetric propagators on the accuracy of phase-contrast velocimetry. Journal of Magnetic Resonance, 325, 106929. (doi: 10.1016/j.jmr.2021.106929) (PMID:33713991)

Al-mubarak, H., Vallatos, A., Gallagher, L., Birch, J., Chalmers, A.J. and Holmes, W.M. (2021) Evaluating potential of multi-parametric MRI using co-registered histology: Application to a mouse model of glioblastoma. Magnetic resonance imaging, 85, pp. 121-127. (doi: 10.1016/j.mri.2021.10.030) (PMID:34687852)

2020

Alshuhri, M. S. , Gallagher, L., McCabe, C. and Holmes, W. M. (2020) Change in CSF dynamics responsible for ICP elevation after ischemic stroke in rats: a new mechanism for unexplained END? Translational Stroke Research, 11, pp. 310-318. (doi: 10.1007/s12975-019-00719-6)

2019

Al-Mubarak, H., Vallatos, A., Gallagher, L., Birch, J., Gilmour, L., Foster, J., Chalmers, A.J. and Holmes, W.M. (2019) Stacked in-plane histology for quantitative validation of non-invasive imaging biomarkers: application to an infiltrative brain tumour model. Journal of Neuroscience Methods, 326, 108372. (doi: 10.1016/j.jneumeth.2019.108372) (PMID:31348965)

Vallatos, A., Al-Mubarak, H.F.I., Birch, J.L., Gallagher, L., Mullin, J.M., Gilmour, L., Holmes, W.M. and Chalmers, A.J. (2019) Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region. Journal of Magnetic Resonance Imaging, 50(2), pp. 529-540. (doi: 10.1002/jmri.26580) (PMID:30569620)

Arroja, M.M.C., Reid, E. , Roy, L.A., Vallatos, A.V., Holmes, W.M. , Nicklin, S.A. , Work, L.M. and McCabe, C. (2019) Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion. Scientific Reports, 9, 3154. (doi: 10.1038/s41598-019-39102-8) (PMID:30816157) (PMCID:PMC6395816)

Jones, F. E. et al. (2019) 4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease. Human Molecular Genetics, 28(4), pp. 628-638. (doi: 10.1093/hmg/ddy369) (PMID:30351356) (PMCID:PMC6360271)

2018

Birch, J. L. et al. (2018) A novel small-molecule inhibitor of MRCK prevents radiation-driven invasion in glioblastoma. Cancer Research, 78(22), pp. 6509-6522. (doi: 10.1158/0008-5472.CAN-18-1697) (PMID:30279244)

Vallatos, A., Al Mubarak, H. F.I., Mullin, J. M. and Holmes, W. M. (2018) Accuracy of phase-contrast velocimetry in systems with skewed intravoxel velocity distributions. Journal of Magnetic Resonance, 296, pp. 121-129. (doi: 10.1016/j.jmr.2018.09.002) (PMID:30245475)

Vallatos, A., Shukla, M. N., Mullin, J. M., Phoenix, V. R. and Holmes, W. M. (2018) The effect of displacement distribution asymmetry on the accuracy of phase-shift velocimetry in porous media. Microporous and Mesoporous Materials, 269, pp. 130-133. (doi: 10.1016/j.micromeso.2017.11.048)

Merrifield, G. D., Brydges, N. M., Hall, L., Mullin, J., Gallagher, L., Pizzi, R. and Holmes, W. M. (2018) Measures of cardiac function in Theraphosidae spiders using in vivo magnetic resonance imaging. Physiological Entomology, 43(3), pp. 207-213. (doi: 10.1111/phen.12245)

Deuchar, G. A., Brennan, D., Holmes, W. M. , Shaw, M., Macrae, I. M. and Santosh, C. (2018) Perfluorocarbon Enhanced Glasgow Oxygen Level Dependent (GOLD) magnetic resonance metabolic imaging identifies the penumbra following acute ischemic stroke. Theranostics, 8(6), pp. 1706-1722. (doi: 10.7150/thno.21685)

Holmes, W. M. , Vallatos, A., Gilmour, L. and Chalmers, A. J. (2018) Multiple boli arterial spin labelling for high signal-to-noise rodent brain perfusion imaging. Magnetic Resonance in Medicine, 79(2), pp. 1020-1030. (doi: 10.1002/mrm.26706) (PMID:28516482)

Thow, L. A., MacDonald, K., Holmes, W. M. , Muir, K. W. , Macrae, I. M. and Dewar, D. (2018) Hyperglycaemia does not increase perfusion deficits after focal cerebral ischaemia in male Wistar rats. Brain and Neuroscience Advances, 2, pp. 1-13. (doi: 10.1177/2398212818794820)

2017

Merrifield, G. D., Mullin, J., Gallagher, L., Tucker, C., Jansen, M. A., Denvir, M. and Holmes, W. M. (2017) Rapid and recoverable in vivo magnetic resonance imaging of the adult zebrafish at 7T. Magnetic Resonance Imaging, 37, pp. 9-15. (doi: 10.1016/j.mri.2016.10.013) (PMID:27751860) (PMCID:PMC5344283)

Faller, K. M.E., Leach, J., Johnston, P. , Holmes, W. M. , Macrae, I. M. and Frenguelli, B. G. (2017) Proof of concept and feasibility studies examining the influence of combination ribose, adenine and allopurinol treatment on stroke outcome in the rat. Brain and Neuroscience Advances, 1, pp. 1-13. (doi: 10.1177/2398212817717112)

2016

Milidonis, X., Lennen, R. J., Jansen, M. A., Mueller, S., Boehm-Sturm, P., Holmes, W. M. , Sena, E. S., Macleod, M. R. and Marshall, I. (2016) Multicenter evaluation of geometric accuracy of MRI protocols used in experimental stroke. PLoS ONE, 11(9), e0162545. (doi: 10.1371/journal.pone.0162545) (PMID:27603704) (PMCID:PMC5014410)

Lavery, C. A., Kurowska-Stolarska, M. , Holmes, W. , Donnelly, I., Caslake, M., Collier, A., Baker, A. H. and Miller, A. M. (2016) miR-34a-/- mice are susceptible to diet-induced obesity. Obesity, 24(8), pp. 1741-1751. (doi: 10.1002/oby.21561) (PMID:27377585) (PMCID:PMC4979678)

Lopez Gonzalez, M.R., Foo, S.Y., Holmes, W.M. , Stewart, W. , Condon, B., Muir, K.W. , Welch, G. and Forbes, K.P. (2016) Atherosclerotic carotid plaque composition: a 3T and 7T MRI-histology correlation study. Journal of Neuroimaging, 26(4), pp. 406-413. (doi: 10.1111/jon.12332) (PMID:26919134)

Shukla, M. N., Vallatos, A., Phoenix, V. R. and Holmes, W. M. (2016) Accurate phase-shift velocimetry in rock. Journal of Magnetic Resonance, 267, pp. 43-53. (doi: 10.1016/j.jmr.2016.04.006) (PMID:27111139)

2015

Lakshmanan, S., Holmes, W.M. , Sloan, W.T. and Phoenix, V.R. (2015) Characterization of nanoparticle transport through quartz and dolomite gravels by magnetic resonance imaging. International Journal of Environmental Science and Technology, 12(10), pp. 3373-3384. (doi: 10.1007/s13762-015-0767-4)

Lakshmanan, S., Haynes, H., Vignaga, E., Ockleford, A.-M. and Holmes, W. (2015) The emerging use of magnetic resonance imaging to study river bed dynamics. Spectroscopy Europe, 27(5), pp. 6-8.

Lakshmanan, S., Holmes, W. M. , Sloan, W. T. and Phoenix, V. R. (2015) Nanoparticle transport in saturated porous medium using magnetic resonance imaging. Chemical Engineering Journal, 266, pp. 156-162. (doi: 10.1016/j.cej.2014.12.076)

Murtha, L. A., McLeod, D. D., Pepperall, D., McCann, S. K., Beard, D. J., Tomkins, A. J., Holmes, W. M. , McCabe, C. , Macrae, I. M. and Spratt, N. J. (2015) Intracranial pressure elevation after ischemic stroke in rats: cerebral edema is not the only cause, and short-duration mild hypothermia is a highly effective preventive therapy. Journal of Cerebral Blood Flow and Metabolism, 35, pp. 592-600. (doi: 10.1038/jcbfm.2014.230) (PMID:25515213)

Baskerville, T. A., Macrae, I. M., Holmes, W. M. and McCabe, C. (2015) The influence of gender on ‘tissue at risk’ in acute stroke: A diffusion-weighted magnetic resonance imaging study in a rat model of focal cerebral ischaemia. Journal of Cerebral Blood Flow and Metabolism, 36(2), pp. 381-386. (doi: 10.1177/0271678X15606137) (PMID:26661149)

Pawlikowski, J.S. et al. (2015) Acute inhibition of MEK suppresses congenital melanocytic nevus syndrome in a murine model driven by activated NRAS and Wnt signaling. Journal of Investigative Dermatology, 135(8), pp. 2093-2101. (doi: 10.1038/jid.2015.114) (PMID:25815427) (PMCID:PMC4539947)

2014

Rodie, M., Welsh, M., Holmes, W. , Wudy, S., Hartmann, M., Macrae, I. M. and Ahmed, S. F. (2014) Early Androgen Blockade Influences Longer-Term Brain Metabolism As Assessed By Magnetic Resonance Spectroscopy. In: Endocrine Society's 96th Annual Meeting and Expo, Chicago, IL, USA, 21-24 Jun 2014,

Douglas, F.J., MacLaren, D.A. , Tuna, F., Holmes, W.H. , Berry, C.C. and Murrie, M. (2014) Formation of octapod MnO nanoparticles with enhanced magnetic properties through kinetically-controlled thermal decomposition of polynuclear manganese complexes. Nanoscale, 6(1), p. 172. (doi: 10.1039/C3NR04832B)

Lakshmanan, S., Pender, G., Haynes, H. and Holmes, W. (2014) Characterization of flow transport within pore spaces of an open-work gravel bed. International Journal of Engineering and Technology, 3(4), pp. 457-463. (doi: 10.14419/ijet.v3i4.3430)

Mazen, M. M., MacLellan, S., Dufes, C., Holmes, W. M. , Condon, B., Uchegbu, I. F. and Schätzlein, A. G. (2014) Size-tuneable nanometric MRI contrast agents for the imaging of molecular weight dependent transport processes. Pharmaceutical Nanotechnology, 2(3), pp. 129-137. (doi: 10.2174/2211738503999141222224739)

Murray, K.N., Girard, S., Holmes, W.M. , Parkes, L.M., Williams, S.R., Parry-Jones, A.R. and Allan, S.M. (2014) Systemic inflammation impairs tissue reperfusion through endothelin-dependent mechanisms in cerebral ischemia. Stroke, 45(11), pp. 3412-3419. (doi: 10.1161/STROKEAHA.114.006613) (PMID:25228257) (PMCID:PMC4363555)

Robertson, C. A., McCabe, C. , Lopez-Gonzalez, M. R., Deuchar, G. A., Dani, K., Holmes, W. M. , Muir, K. W. , Santosh, C. and Macrae, I. M. (2014) Detection of ischemic penumbra using combined perfusion and T2* oxygen challenge imaging. International Journal of Stroke, 10(1), pp. 42-50. (doi: 10.1111/ijs.12327)

Wetterling, F., Gallagher, L., Mullin, J., Holmes, W. M. , McCabe, C. , Macrae, I. M. and Fagan, A. J. (2014) Sodium-23 magnetic resonance imaging has potential for improving penumbra detection but not for estimating stroke onset time. Journal of Cerebral Blood Flow and Metabolism, 35(1), pp. 103-110. (doi: 10.1038/jcbfm.2014.174)

2013

Howard, L.E., Holmes, W.M., Ferrando, S., Maclaine, J.S., Kelsh, R.N., Ramsey, A., Abel, R.L. and Cox, J.P.L. (2013) Functional nasal morphology of chimaerid fishes. Journal of Morphology, 274(9), pp. 987-1009. (doi: 10.1002/jmor.20156)

Ramanan, B., Holmes, W.M. , Sloan, W.T. and Phoenix, V.R. (2013) Magnetic resonance imaging of mass transport and structure inside a phototrophic biofilm. Current Microbiology, 66(5), pp. 456-461. (doi: 10.1007/s00284-012-0292-3)

Brittain, J.F. et al. (2013) An MRI-histological study of white matter in stroke-free SHRSP. Journal of Cerebral Blood Flow and Metabolism, 33(5), pp. 760-763. (doi: 10.1038/jcbfm.2013.14)

Tarr, D., Graham, D. , Roy, L.A., Holmes, W.M. , McCabe, C. , Macrae, I.M., Muir, K.W. and Dewar, D. (2013) Hyperglycemia accelerates apparent diffusion coefficient-defined lesion growth after focal cerebral ischemia in rats with and without features of metabolic syndrome. Journal of Cerebral Blood Flow and Metabolism, 33(10), pp. 1556-1563. (doi: 10.1038/jcbfm.2013.107)

2012

Haynes, H., Ockelford, A.-M., Vignaga, E. and Holmes, W.M. (2012) A new approach to define surface/sub-surface transition in gravel beds. Acta Geophysica, 60(6), pp. 1589-1606. (doi: 10.2478/s11600-012-0067-z)

Reid, E. , Graham, D. , Lopez-Gonzalez, M. R., Holmes, W. M. , Macrae, I. M. and McCabe, C. (2012) Penumbra detection using PWI/DWI mismatch MRI in a rat stroke model with and without comorbidity: comparison of methods. Journal of Cerebral Blood Flow and Metabolism, 32(9), pp. 1765-1777. (doi: 10.1038/jcbfm.2012.69) (PMID:22669479) (PMCID:PMC3434632)

Baskerville, T., McCabe, C. , Weir, C.J., Macrae, I.M. and Holmes, W. (2012) Noninvasive MRI measurement of CBF: evaluating an arterial spin labelling sequence with ^99mTc- HMPAO CBF autoradiography in a rat stroke model. Journal of Cerebral Blood Flow and Metabolism, 32(6), pp. 973-977. (doi: 10.1038/jcbfm.2012.19) (PMID:22472604) (PMCID:PMC3367221)

Ramanan, B., Holmes, W.M. , Sloan, W.T. and Phoenix, V.R. (2012) Investigation of nanoparticle transport inside coarse-grained geological media using magnetic resonance imaging. Environmental Science and Technology, 46(1), pp. 360-366. (doi: 10.1021/es2012726) (PMID:22091923)

Haynes, H. and Holmes, W.M. (2012) Imaging sediment structure: the emerging use of Magnetic Resonance Imaging (MRI) for 3D analysis of sediment structures and internal flow processes. In: Clarke, L.E. (ed.) Geomorphological Techniques. British Society for Geomorphology: London.

Holmes, W.M. , Lopez-Gonzalez, M.R., Gallagher, L., Deuchar, G., Macrae, I. and Santosh, C. (2012) Novel MRI detection of the ischemic penumbra: direct assessment of metabolic integrity. NMR in Biomedicine, 25(2), pp. 295-304. (doi: 10.1002/nbm.1748)

2011

Ruest, T., Holmes, W.M. , Barrie, J.A., Griffiths, I.R., Anderson, T.J. , Dewar, D. and Edgar, J.M. (2011) High-resolution diffusion tensor imaging of fixed brain in a mouse model of Pelizaeus-Merzbacher disease: comparison with quantitative measures of white matter pathology. NMR in Biomedicine, 24(10), pp. 1369-1379. (doi: 10.1002/nbm.1700)

Baskerville, T., Deuchar, G. A., McCabe, C. , Robertson, C. A., Holmes, W. M. , Santosh, C. and Macrae, I. M. (2011) Influence of 100% and 40% oxygen on penumbral blood flow, oxygen level, and T2*-weighted MRI in a rat stroke model. Journal of Cerebral Blood Flow and Metabolism, 31(8), pp. 1799-1806. (doi: 10.1038/jcbfm.2011.65)

Robertson, C. A., McCabe, C. , Gallagher, L., Lopez Gonzalez, M. d., Holmes, W. M. , Condon, B., Muir, K. W. , Santosh, C. and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 2. Validation based on the consequences of reperfusion. Journal of Cerebral Blood Flow and Metabolism, 31(8), pp. 1788-1798. (doi: 10.1038/jcbfm.2011.67)

Robertson, C. A., McCabe, C. , Gallagher, L., Lopez-Gonzalez, M. d., Holmes, W. M. , Condon, B., Muir, K. W. , Santosh, C. and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography. Journal of Cerebral Blood Flow and Metabolism, 31, pp. 1778-1787. (doi: 10.1038/jcbfm.2011.66)

Holmes, W.M. , Cotton, R., Xuan, V.B., Rygg, A.D., Craven, B.A., Abel, R.L., Slack, R. and Cox, J.P.L. (2011) Three-dimensional structure of the nasal passageway of a hagfish and its implications for olfaction. Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 294(6), pp. 1045-1056. (doi: 10.1002/ar.21382)

Moldrich, R.X. et al. (2011) Fgfr3 regulates development of the caudal telencephalon. Developmental Dynamics, 240(6), pp. 1586-1599. (doi: 10.1002/dvdy.22636) (PMID:21491541)

Glasgow University and Greater Glasgow and Clyde Health Board (2011) Improved Method of Determining Metabolic Function. .

2010

Miller, A. M., Asquith, D. L., Hueber, A. J., Anderson, L. A., Holmes, W. M. , McKenzie, A. N., Xu, D., Sattar, N. , McInnes, I. B. and Liew, F. Y. (2010) Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice. Circulation Research, 107(5), pp. 650-658. (doi: 10.1161/CIRCRESAHA.110.218867) (PMID:20634488) (PMCID:PMC4254700)

Dani, K. A., Santosh, C., Brennan, D., McCabe, C. , Holmes, W. M. , Condon, B., Hadley, D. M., Macrae, I. M., Shaw, M. and Muir, K. W. (2010) T2*-weighted magnetic resonance imaging with hyperoxia in acute ischemic stroke. Annals of Neurology, 68(1), pp. 37-47. (doi: 10.1002/ana.22032)

Ramanan, B., Holmes, W.M. , Sloan, W.T. and Phoenix, V.R. (2010) Application of Paramagnetically Tagged Molecules for Magnetic Resonance Imaging of Biofilm Mass Transport Processes. Applied and Environmental Microbiology, 76(12), pp. 4027-4036. (doi: 10.1128/AEM.03016-09)

2009

Haynes, H., Vignaga, E. and Holmes, W.M. (2009) Using magnetic resonance imaging for experimental analysis of fine-sediment infiltration into gravel beds. Sedimentology, 56(7), pp. 1961-1975. (doi: 10.1111/j.1365-3091.2009.01064.x)

Holmes, W.H. , McCabe, C. , Mullin, J.M., Condon, B. and Bain, M.M. (2009) In ovo non-invasive quantification of the myocardial function and mass of chick embryos using magnetic resonance imaging. NMR in Biomedicine, 22(7), pp. 745-752. (doi: 10.1002/nbm.1386)

2008

Santosh, C. et al. (2008) Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra. Journal of Cerebral Blood Flow and Metabolism, 28(10), pp. 1742-1753. (doi: 10.1038/jcbfm.2008.56)

Phoenix, V.R. and Holmes, W.M. (2008) Magnetic resonance imaging of structure, diffusivity, and copper immobilization in a phototrophic biofilm. Applied and Environmental Microbiology, 74(15), pp. 4934-4943. (doi: 10.1128/AEM.02783-07)

Holmes, W.M., McCabe, C., Mullin, J.M., Condon, B. and Bain, M.M. (2008) Noninvasive self-gated magnetic resonance cardiac imaging of developing chick embryos in ovo. Circulation, 117(21), E346-E347. (doi: 10.1161/CIRCULATIONAHA.107.747154)

Phoenix, V.R. , Holmes, W.M. and Ramanan, B. (2008) Magnetic resonance imaging (MRI) of heavy-metal transport and fate in an artificial biofilm. Mineralogical Magazine, 72(1), pp. 483-486. (doi: 10.1180/minmag.2008.072.1.483)

Holmes, W., Maclellan, S., Condon, B., Dufes, C., Evans, T. , Uchegbu, I. and Schatzlein, A. (2008) High-resolution 3D isotropic MR imaging of mouse flank tumours obtained in vivo with solenoid RF micro-coil. Physics in Medicine and Biology, 53(2), pp. 505-513. (doi: 10.1088/0031-9155/53/2/015)

2006

Lopez-Gonzalez, M., Holmes, W. and Callaghan, P. (2006) Rheo-NMR phenomena of wormlike micelles. Soft Matter, 2(10), pp. 855-869.

2005

Watts, J., Gabruzsk, J. and Holmes, W. (2005) Ligand-mediated anticodon conformational changes occur during tRNA methylation by a TrmD methyltransferase. Biochemistry, 44(17), pp. 6629-6639.

2004

Holmes, W., Callaghan, P., Vlassopoulos, D. and Roovers, J. (2004) Shear banding phenomena in ultrasoft colloidal glasses. Journal of Rheology, 48(5), pp. 1085-1102.

Holmes, W., Lopez-Gonzalez, M. and Callaghan, P. (2004) Shear-induced constraint to amphiphile chain dynamics in wormlike micelles. Europhysics Letters, 66(1), pp. 132-138.

Holmes, W., Lopez-Gonzalez, M. and Callaghan, P. (2004) Shear-induced constraint to amphiphile chain dynamics in wormlike micelles (vol 66, pg 132, 2004). Europhysics Letters, 66(3), p. 464.

Holmes, W. and Packer, K. (2004) Investigation of phase trapping by secondary imbibition within Fontainebleau sandstone. Chemical Engineering Science, 59(14), pp. 2891-2898.

Lopez-Gonzalez, M., Holmes, W., Callaghan, P. and Photinos, P. (2004) Shear banding fluctuations and nematic order in wormlike micelles. Physical Review Letters, 93(26),

2003

Holmes, W., Lopez-Gonzalez, M. and Callaghan, P. (2003) Fluctuations in shear-banded flow seen by NMR velocimetry. Europhysics Letters, 64(2), pp. 274-280.

Holmes, W. and Packer, K. (2003) Investigation of two phase flow and phase trapping by secondary imbibition within fontainebleau sandstone. Magnetic Resonance Imaging, 21(3-4), pp. 389-391.

2002

Holmes, W. and Packer, K. (2002) Investigation of thin surface-wetting films in two-phase saturated porous media. Magnetic Resonance in Chemistry, 40, S20-S28.

2001

Holmes, W., De Panfilis, C. and Packer, K. (2001) Diffusion in thin films on the surface of a porous solid. Magnetic Resonance Imaging, 19(3-4), pp. 525-526.

Holmes, W., Graham, R. and Packer, K. (2001) Diffusion in surface-wetting films in a two-phase saturated porous solid characterised by pulsed magnetic field gradient NMR. Chemical Engineering Journal, 83(1), pp. 33-38.

2000

Graham, R.G., Holmes, W.M., De Panfilis, C. and Packer, K.J. (2000) Characterisation of locally anisotropic structures within isotropic porous solids using 2-D pulsed field gradient NMR. Chemical Physics Letters, 332(3-4), pp. 319-323. (doi: 10.1016/S0009-2614(00)01279-3)

Articles

Guan, D., Zhuan, X., Holmes, W. , Luo, X. and Gao, H. (2021) Modelling of fibre dispersion and its effects on cardiac mechanics from diastole to systole. Journal of Engineering Mathematics, 128, 1. (doi: 10.1007/s10665-021-10102-w)

Al-Mubarak, H. F.I., Vallatos, A. and Holmes, W. M. (2021) Impact of turbulence-induced asymmetric propagators on the accuracy of phase-contrast velocimetry. Journal of Magnetic Resonance, 325, 106929. (doi: 10.1016/j.jmr.2021.106929) (PMID:33713991)

Al-mubarak, H., Vallatos, A., Gallagher, L., Birch, J., Chalmers, A.J. and Holmes, W.M. (2021) Evaluating potential of multi-parametric MRI using co-registered histology: Application to a mouse model of glioblastoma. Magnetic resonance imaging, 85, pp. 121-127. (doi: 10.1016/j.mri.2021.10.030) (PMID:34687852)

Alshuhri, M. S. , Gallagher, L., McCabe, C. and Holmes, W. M. (2020) Change in CSF dynamics responsible for ICP elevation after ischemic stroke in rats: a new mechanism for unexplained END? Translational Stroke Research, 11, pp. 310-318. (doi: 10.1007/s12975-019-00719-6)

Al-Mubarak, H., Vallatos, A., Gallagher, L., Birch, J., Gilmour, L., Foster, J., Chalmers, A.J. and Holmes, W.M. (2019) Stacked in-plane histology for quantitative validation of non-invasive imaging biomarkers: application to an infiltrative brain tumour model. Journal of Neuroscience Methods, 326, 108372. (doi: 10.1016/j.jneumeth.2019.108372) (PMID:31348965)

Vallatos, A., Al-Mubarak, H.F.I., Birch, J.L., Gallagher, L., Mullin, J.M., Gilmour, L., Holmes, W.M. and Chalmers, A.J. (2019) Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region. Journal of Magnetic Resonance Imaging, 50(2), pp. 529-540. (doi: 10.1002/jmri.26580) (PMID:30569620)

Arroja, M.M.C., Reid, E. , Roy, L.A., Vallatos, A.V., Holmes, W.M. , Nicklin, S.A. , Work, L.M. and McCabe, C. (2019) Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion. Scientific Reports, 9, 3154. (doi: 10.1038/s41598-019-39102-8) (PMID:30816157) (PMCID:PMC6395816)

Jones, F. E. et al. (2019) 4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease. Human Molecular Genetics, 28(4), pp. 628-638. (doi: 10.1093/hmg/ddy369) (PMID:30351356) (PMCID:PMC6360271)

Birch, J. L. et al. (2018) A novel small-molecule inhibitor of MRCK prevents radiation-driven invasion in glioblastoma. Cancer Research, 78(22), pp. 6509-6522. (doi: 10.1158/0008-5472.CAN-18-1697) (PMID:30279244)

Vallatos, A., Al Mubarak, H. F.I., Mullin, J. M. and Holmes, W. M. (2018) Accuracy of phase-contrast velocimetry in systems with skewed intravoxel velocity distributions. Journal of Magnetic Resonance, 296, pp. 121-129. (doi: 10.1016/j.jmr.2018.09.002) (PMID:30245475)

Vallatos, A., Shukla, M. N., Mullin, J. M., Phoenix, V. R. and Holmes, W. M. (2018) The effect of displacement distribution asymmetry on the accuracy of phase-shift velocimetry in porous media. Microporous and Mesoporous Materials, 269, pp. 130-133. (doi: 10.1016/j.micromeso.2017.11.048)

Merrifield, G. D., Brydges, N. M., Hall, L., Mullin, J., Gallagher, L., Pizzi, R. and Holmes, W. M. (2018) Measures of cardiac function in Theraphosidae spiders using in vivo magnetic resonance imaging. Physiological Entomology, 43(3), pp. 207-213. (doi: 10.1111/phen.12245)

Deuchar, G. A., Brennan, D., Holmes, W. M. , Shaw, M., Macrae, I. M. and Santosh, C. (2018) Perfluorocarbon Enhanced Glasgow Oxygen Level Dependent (GOLD) magnetic resonance metabolic imaging identifies the penumbra following acute ischemic stroke. Theranostics, 8(6), pp. 1706-1722. (doi: 10.7150/thno.21685)

Holmes, W. M. , Vallatos, A., Gilmour, L. and Chalmers, A. J. (2018) Multiple boli arterial spin labelling for high signal-to-noise rodent brain perfusion imaging. Magnetic Resonance in Medicine, 79(2), pp. 1020-1030. (doi: 10.1002/mrm.26706) (PMID:28516482)

Thow, L. A., MacDonald, K., Holmes, W. M. , Muir, K. W. , Macrae, I. M. and Dewar, D. (2018) Hyperglycaemia does not increase perfusion deficits after focal cerebral ischaemia in male Wistar rats. Brain and Neuroscience Advances, 2, pp. 1-13. (doi: 10.1177/2398212818794820)

Merrifield, G. D., Mullin, J., Gallagher, L., Tucker, C., Jansen, M. A., Denvir, M. and Holmes, W. M. (2017) Rapid and recoverable in vivo magnetic resonance imaging of the adult zebrafish at 7T. Magnetic Resonance Imaging, 37, pp. 9-15. (doi: 10.1016/j.mri.2016.10.013) (PMID:27751860) (PMCID:PMC5344283)

Faller, K. M.E., Leach, J., Johnston, P. , Holmes, W. M. , Macrae, I. M. and Frenguelli, B. G. (2017) Proof of concept and feasibility studies examining the influence of combination ribose, adenine and allopurinol treatment on stroke outcome in the rat. Brain and Neuroscience Advances, 1, pp. 1-13. (doi: 10.1177/2398212817717112)

Milidonis, X., Lennen, R. J., Jansen, M. A., Mueller, S., Boehm-Sturm, P., Holmes, W. M. , Sena, E. S., Macleod, M. R. and Marshall, I. (2016) Multicenter evaluation of geometric accuracy of MRI protocols used in experimental stroke. PLoS ONE, 11(9), e0162545. (doi: 10.1371/journal.pone.0162545) (PMID:27603704) (PMCID:PMC5014410)

Lavery, C. A., Kurowska-Stolarska, M. , Holmes, W. , Donnelly, I., Caslake, M., Collier, A., Baker, A. H. and Miller, A. M. (2016) miR-34a-/- mice are susceptible to diet-induced obesity. Obesity, 24(8), pp. 1741-1751. (doi: 10.1002/oby.21561) (PMID:27377585) (PMCID:PMC4979678)

Lopez Gonzalez, M.R., Foo, S.Y., Holmes, W.M. , Stewart, W. , Condon, B., Muir, K.W. , Welch, G. and Forbes, K.P. (2016) Atherosclerotic carotid plaque composition: a 3T and 7T MRI-histology correlation study. Journal of Neuroimaging, 26(4), pp. 406-413. (doi: 10.1111/jon.12332) (PMID:26919134)

Shukla, M. N., Vallatos, A., Phoenix, V. R. and Holmes, W. M. (2016) Accurate phase-shift velocimetry in rock. Journal of Magnetic Resonance, 267, pp. 43-53. (doi: 10.1016/j.jmr.2016.04.006) (PMID:27111139)

Lakshmanan, S., Holmes, W.M. , Sloan, W.T. and Phoenix, V.R. (2015) Characterization of nanoparticle transport through quartz and dolomite gravels by magnetic resonance imaging. International Journal of Environmental Science and Technology, 12(10), pp. 3373-3384. (doi: 10.1007/s13762-015-0767-4)

Lakshmanan, S., Haynes, H., Vignaga, E., Ockleford, A.-M. and Holmes, W. (2015) The emerging use of magnetic resonance imaging to study river bed dynamics. Spectroscopy Europe, 27(5), pp. 6-8.

Lakshmanan, S., Holmes, W. M. , Sloan, W. T. and Phoenix, V. R. (2015) Nanoparticle transport in saturated porous medium using magnetic resonance imaging. Chemical Engineering Journal, 266, pp. 156-162. (doi: 10.1016/j.cej.2014.12.076)

Murtha, L. A., McLeod, D. D., Pepperall, D., McCann, S. K., Beard, D. J., Tomkins, A. J., Holmes, W. M. , McCabe, C. , Macrae, I. M. and Spratt, N. J. (2015) Intracranial pressure elevation after ischemic stroke in rats: cerebral edema is not the only cause, and short-duration mild hypothermia is a highly effective preventive therapy. Journal of Cerebral Blood Flow and Metabolism, 35, pp. 592-600. (doi: 10.1038/jcbfm.2014.230) (PMID:25515213)

Baskerville, T. A., Macrae, I. M., Holmes, W. M. and McCabe, C. (2015) The influence of gender on ‘tissue at risk’ in acute stroke: A diffusion-weighted magnetic resonance imaging study in a rat model of focal cerebral ischaemia. Journal of Cerebral Blood Flow and Metabolism, 36(2), pp. 381-386. (doi: 10.1177/0271678X15606137) (PMID:26661149)

Pawlikowski, J.S. et al. (2015) Acute inhibition of MEK suppresses congenital melanocytic nevus syndrome in a murine model driven by activated NRAS and Wnt signaling. Journal of Investigative Dermatology, 135(8), pp. 2093-2101. (doi: 10.1038/jid.2015.114) (PMID:25815427) (PMCID:PMC4539947)

Douglas, F.J., MacLaren, D.A. , Tuna, F., Holmes, W.H. , Berry, C.C. and Murrie, M. (2014) Formation of octapod MnO nanoparticles with enhanced magnetic properties through kinetically-controlled thermal decomposition of polynuclear manganese complexes. Nanoscale, 6(1), p. 172. (doi: 10.1039/C3NR04832B)

Lakshmanan, S., Pender, G., Haynes, H. and Holmes, W. (2014) Characterization of flow transport within pore spaces of an open-work gravel bed. International Journal of Engineering and Technology, 3(4), pp. 457-463. (doi: 10.14419/ijet.v3i4.3430)

Mazen, M. M., MacLellan, S., Dufes, C., Holmes, W. M. , Condon, B., Uchegbu, I. F. and Schätzlein, A. G. (2014) Size-tuneable nanometric MRI contrast agents for the imaging of molecular weight dependent transport processes. Pharmaceutical Nanotechnology, 2(3), pp. 129-137. (doi: 10.2174/2211738503999141222224739)

Murray, K.N., Girard, S., Holmes, W.M. , Parkes, L.M., Williams, S.R., Parry-Jones, A.R. and Allan, S.M. (2014) Systemic inflammation impairs tissue reperfusion through endothelin-dependent mechanisms in cerebral ischemia. Stroke, 45(11), pp. 3412-3419. (doi: 10.1161/STROKEAHA.114.006613) (PMID:25228257) (PMCID:PMC4363555)

Robertson, C. A., McCabe, C. , Lopez-Gonzalez, M. R., Deuchar, G. A., Dani, K., Holmes, W. M. , Muir, K. W. , Santosh, C. and Macrae, I. M. (2014) Detection of ischemic penumbra using combined perfusion and T2* oxygen challenge imaging. International Journal of Stroke, 10(1), pp. 42-50. (doi: 10.1111/ijs.12327)

Wetterling, F., Gallagher, L., Mullin, J., Holmes, W. M. , McCabe, C. , Macrae, I. M. and Fagan, A. J. (2014) Sodium-23 magnetic resonance imaging has potential for improving penumbra detection but not for estimating stroke onset time. Journal of Cerebral Blood Flow and Metabolism, 35(1), pp. 103-110. (doi: 10.1038/jcbfm.2014.174)

Howard, L.E., Holmes, W.M., Ferrando, S., Maclaine, J.S., Kelsh, R.N., Ramsey, A., Abel, R.L. and Cox, J.P.L. (2013) Functional nasal morphology of chimaerid fishes. Journal of Morphology, 274(9), pp. 987-1009. (doi: 10.1002/jmor.20156)

Ramanan, B., Holmes, W.M. , Sloan, W.T. and Phoenix, V.R. (2013) Magnetic resonance imaging of mass transport and structure inside a phototrophic biofilm. Current Microbiology, 66(5), pp. 456-461. (doi: 10.1007/s00284-012-0292-3)

Brittain, J.F. et al. (2013) An MRI-histological study of white matter in stroke-free SHRSP. Journal of Cerebral Blood Flow and Metabolism, 33(5), pp. 760-763. (doi: 10.1038/jcbfm.2013.14)

Tarr, D., Graham, D. , Roy, L.A., Holmes, W.M. , McCabe, C. , Macrae, I.M., Muir, K.W. and Dewar, D. (2013) Hyperglycemia accelerates apparent diffusion coefficient-defined lesion growth after focal cerebral ischemia in rats with and without features of metabolic syndrome. Journal of Cerebral Blood Flow and Metabolism, 33(10), pp. 1556-1563. (doi: 10.1038/jcbfm.2013.107)

Haynes, H., Ockelford, A.-M., Vignaga, E. and Holmes, W.M. (2012) A new approach to define surface/sub-surface transition in gravel beds. Acta Geophysica, 60(6), pp. 1589-1606. (doi: 10.2478/s11600-012-0067-z)

Reid, E. , Graham, D. , Lopez-Gonzalez, M. R., Holmes, W. M. , Macrae, I. M. and McCabe, C. (2012) Penumbra detection using PWI/DWI mismatch MRI in a rat stroke model with and without comorbidity: comparison of methods. Journal of Cerebral Blood Flow and Metabolism, 32(9), pp. 1765-1777. (doi: 10.1038/jcbfm.2012.69) (PMID:22669479) (PMCID:PMC3434632)

Baskerville, T., McCabe, C. , Weir, C.J., Macrae, I.M. and Holmes, W. (2012) Noninvasive MRI measurement of CBF: evaluating an arterial spin labelling sequence with ^99mTc- HMPAO CBF autoradiography in a rat stroke model. Journal of Cerebral Blood Flow and Metabolism, 32(6), pp. 973-977. (doi: 10.1038/jcbfm.2012.19) (PMID:22472604) (PMCID:PMC3367221)

Ramanan, B., Holmes, W.M. , Sloan, W.T. and Phoenix, V.R. (2012) Investigation of nanoparticle transport inside coarse-grained geological media using magnetic resonance imaging. Environmental Science and Technology, 46(1), pp. 360-366. (doi: 10.1021/es2012726) (PMID:22091923)

Holmes, W.M. , Lopez-Gonzalez, M.R., Gallagher, L., Deuchar, G., Macrae, I. and Santosh, C. (2012) Novel MRI detection of the ischemic penumbra: direct assessment of metabolic integrity. NMR in Biomedicine, 25(2), pp. 295-304. (doi: 10.1002/nbm.1748)

Ruest, T., Holmes, W.M. , Barrie, J.A., Griffiths, I.R., Anderson, T.J. , Dewar, D. and Edgar, J.M. (2011) High-resolution diffusion tensor imaging of fixed brain in a mouse model of Pelizaeus-Merzbacher disease: comparison with quantitative measures of white matter pathology. NMR in Biomedicine, 24(10), pp. 1369-1379. (doi: 10.1002/nbm.1700)

Baskerville, T., Deuchar, G. A., McCabe, C. , Robertson, C. A., Holmes, W. M. , Santosh, C. and Macrae, I. M. (2011) Influence of 100% and 40% oxygen on penumbral blood flow, oxygen level, and T2*-weighted MRI in a rat stroke model. Journal of Cerebral Blood Flow and Metabolism, 31(8), pp. 1799-1806. (doi: 10.1038/jcbfm.2011.65)

Robertson, C. A., McCabe, C. , Gallagher, L., Lopez Gonzalez, M. d., Holmes, W. M. , Condon, B., Muir, K. W. , Santosh, C. and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 2. Validation based on the consequences of reperfusion. Journal of Cerebral Blood Flow and Metabolism, 31(8), pp. 1788-1798. (doi: 10.1038/jcbfm.2011.67)

Robertson, C. A., McCabe, C. , Gallagher, L., Lopez-Gonzalez, M. d., Holmes, W. M. , Condon, B., Muir, K. W. , Santosh, C. and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography. Journal of Cerebral Blood Flow and Metabolism, 31, pp. 1778-1787. (doi: 10.1038/jcbfm.2011.66)

Holmes, W.M. , Cotton, R., Xuan, V.B., Rygg, A.D., Craven, B.A., Abel, R.L., Slack, R. and Cox, J.P.L. (2011) Three-dimensional structure of the nasal passageway of a hagfish and its implications for olfaction. Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 294(6), pp. 1045-1056. (doi: 10.1002/ar.21382)

Moldrich, R.X. et al. (2011) Fgfr3 regulates development of the caudal telencephalon. Developmental Dynamics, 240(6), pp. 1586-1599. (doi: 10.1002/dvdy.22636) (PMID:21491541)

Miller, A. M., Asquith, D. L., Hueber, A. J., Anderson, L. A., Holmes, W. M. , McKenzie, A. N., Xu, D., Sattar, N. , McInnes, I. B. and Liew, F. Y. (2010) Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice. Circulation Research, 107(5), pp. 650-658. (doi: 10.1161/CIRCRESAHA.110.218867) (PMID:20634488) (PMCID:PMC4254700)

Dani, K. A., Santosh, C., Brennan, D., McCabe, C. , Holmes, W. M. , Condon, B., Hadley, D. M., Macrae, I. M., Shaw, M. and Muir, K. W. (2010) T2*-weighted magnetic resonance imaging with hyperoxia in acute ischemic stroke. Annals of Neurology, 68(1), pp. 37-47. (doi: 10.1002/ana.22032)

Ramanan, B., Holmes, W.M. , Sloan, W.T. and Phoenix, V.R. (2010) Application of Paramagnetically Tagged Molecules for Magnetic Resonance Imaging of Biofilm Mass Transport Processes. Applied and Environmental Microbiology, 76(12), pp. 4027-4036. (doi: 10.1128/AEM.03016-09)

Haynes, H., Vignaga, E. and Holmes, W.M. (2009) Using magnetic resonance imaging for experimental analysis of fine-sediment infiltration into gravel beds. Sedimentology, 56(7), pp. 1961-1975. (doi: 10.1111/j.1365-3091.2009.01064.x)

Holmes, W.H. , McCabe, C. , Mullin, J.M., Condon, B. and Bain, M.M. (2009) In ovo non-invasive quantification of the myocardial function and mass of chick embryos using magnetic resonance imaging. NMR in Biomedicine, 22(7), pp. 745-752. (doi: 10.1002/nbm.1386)

Santosh, C. et al. (2008) Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra. Journal of Cerebral Blood Flow and Metabolism, 28(10), pp. 1742-1753. (doi: 10.1038/jcbfm.2008.56)

Phoenix, V.R. and Holmes, W.M. (2008) Magnetic resonance imaging of structure, diffusivity, and copper immobilization in a phototrophic biofilm. Applied and Environmental Microbiology, 74(15), pp. 4934-4943. (doi: 10.1128/AEM.02783-07)

Holmes, W.M., McCabe, C., Mullin, J.M., Condon, B. and Bain, M.M. (2008) Noninvasive self-gated magnetic resonance cardiac imaging of developing chick embryos in ovo. Circulation, 117(21), E346-E347. (doi: 10.1161/CIRCULATIONAHA.107.747154)

Phoenix, V.R. , Holmes, W.M. and Ramanan, B. (2008) Magnetic resonance imaging (MRI) of heavy-metal transport and fate in an artificial biofilm. Mineralogical Magazine, 72(1), pp. 483-486. (doi: 10.1180/minmag.2008.072.1.483)

Holmes, W., Maclellan, S., Condon, B., Dufes, C., Evans, T. , Uchegbu, I. and Schatzlein, A. (2008) High-resolution 3D isotropic MR imaging of mouse flank tumours obtained in vivo with solenoid RF micro-coil. Physics in Medicine and Biology, 53(2), pp. 505-513. (doi: 10.1088/0031-9155/53/2/015)

Lopez-Gonzalez, M., Holmes, W. and Callaghan, P. (2006) Rheo-NMR phenomena of wormlike micelles. Soft Matter, 2(10), pp. 855-869.

Watts, J., Gabruzsk, J. and Holmes, W. (2005) Ligand-mediated anticodon conformational changes occur during tRNA methylation by a TrmD methyltransferase. Biochemistry, 44(17), pp. 6629-6639.

Holmes, W., Callaghan, P., Vlassopoulos, D. and Roovers, J. (2004) Shear banding phenomena in ultrasoft colloidal glasses. Journal of Rheology, 48(5), pp. 1085-1102.

Holmes, W., Lopez-Gonzalez, M. and Callaghan, P. (2004) Shear-induced constraint to amphiphile chain dynamics in wormlike micelles. Europhysics Letters, 66(1), pp. 132-138.

Holmes, W., Lopez-Gonzalez, M. and Callaghan, P. (2004) Shear-induced constraint to amphiphile chain dynamics in wormlike micelles (vol 66, pg 132, 2004). Europhysics Letters, 66(3), p. 464.

Holmes, W. and Packer, K. (2004) Investigation of phase trapping by secondary imbibition within Fontainebleau sandstone. Chemical Engineering Science, 59(14), pp. 2891-2898.

Lopez-Gonzalez, M., Holmes, W., Callaghan, P. and Photinos, P. (2004) Shear banding fluctuations and nematic order in wormlike micelles. Physical Review Letters, 93(26),

Holmes, W., Lopez-Gonzalez, M. and Callaghan, P. (2003) Fluctuations in shear-banded flow seen by NMR velocimetry. Europhysics Letters, 64(2), pp. 274-280.

Holmes, W. and Packer, K. (2003) Investigation of two phase flow and phase trapping by secondary imbibition within fontainebleau sandstone. Magnetic Resonance Imaging, 21(3-4), pp. 389-391.

Holmes, W. and Packer, K. (2002) Investigation of thin surface-wetting films in two-phase saturated porous media. Magnetic Resonance in Chemistry, 40, S20-S28.

Holmes, W., De Panfilis, C. and Packer, K. (2001) Diffusion in thin films on the surface of a porous solid. Magnetic Resonance Imaging, 19(3-4), pp. 525-526.

Holmes, W., Graham, R. and Packer, K. (2001) Diffusion in surface-wetting films in a two-phase saturated porous solid characterised by pulsed magnetic field gradient NMR. Chemical Engineering Journal, 83(1), pp. 33-38.

Graham, R.G., Holmes, W.M., De Panfilis, C. and Packer, K.J. (2000) Characterisation of locally anisotropic structures within isotropic porous solids using 2-D pulsed field gradient NMR. Chemical Physics Letters, 332(3-4), pp. 319-323. (doi: 10.1016/S0009-2614(00)01279-3)

Book Sections

Haynes, H. and Holmes, W.M. (2012) Imaging sediment structure: the emerging use of Magnetic Resonance Imaging (MRI) for 3D analysis of sediment structures and internal flow processes. In: Clarke, L.E. (ed.) Geomorphological Techniques. British Society for Geomorphology: London.

Conference Proceedings

Rodie, M., Welsh, M., Holmes, W. , Wudy, S., Hartmann, M., Macrae, I. M. and Ahmed, S. F. (2014) Early Androgen Blockade Influences Longer-Term Brain Metabolism As Assessed By Magnetic Resonance Spectroscopy. In: Endocrine Society's 96th Annual Meeting and Expo, Chicago, IL, USA, 21-24 Jun 2014,

Patents

Glasgow University and Greater Glasgow and Clyde Health Board (2011) Improved Method of Determining Metabolic Function. .