Dr Julie-Myrtille Bourgognon

  • Lecturer (School of Psychology & Neuroscience Administration)

Research interests

As a neurocsientist, I focus on the molecular processes leading to stress and anxiety related behaviours;  I also spent several years studying neurodegeneration, neuroinflammation, and prion diseases, with a particular interest in GPCRs and nitric oxide. My interdisciplinary approach combined cellular and molecular biology, neuroimaging, electrophysiology and behavioral assays.

Publications

List by: Type | Date

Jump to: 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2013 | 2011 | 2010
Number of items: 14.

2022

Spiers, J. G., Cortina Chen, H.-J., Barry, T. L., Bourgognon, J.-M. and Steinert, J. R. (2022) Redox stress and metal dys-homeostasis appear as hallmarks of early prion disease pathogenesis in mice. Free Radical Biology and Medicine, 192, pp. 182-190. (doi: 10.1016/j.freeradbiomed.2022.09.025) (PMID:36170956)

2021

Bourgognon, J.-M. , Spiers, J. G., Robinson, S. W., Scheiblich, H., Glynn, P., Ortori, C., Bradley, S. J. , Tobin, A. B. and Steinert, J. R. (2021) Inhibition of neuroinflammatory nitric oxide signaling suppresses glycation and prevents neuronal dysfunction in mouse prion disease. Proceedings of the National Academy of Sciences of the United States of America, 118(10), e200957911. (doi: 10.1073/pnas.2009579118) (PMID:33653950)

Bourgognon, J.-M. , McColl, A., Suessmilch, M., Krishnadas, R. and Cavanagh, J. (2021) Stress, immune system and the brain. In: Textbook of Immunopsychiatry. Cambridge University Press: Cambridge, pp. 51-72. ISBN 9781108539623 (doi: 10.1017/9781108539623.004)

2020

Bourgognon, J.-M. and Cavanagh, J. (2020) The role of cytokines in modulating learning and memory and brain plasticity. Brain and Neuroscience Advances, 4, pp. 1-13. (doi: 10.1177/2398212820979802) (PMID:33415308) (PMCID:PMC7750764)

2019

Spiers, J. G., Chen, H.-J. C., Bourgognon, J.-M. and Steinert, J. R. (2019) Dysregulation of stress systems and nitric oxide signaling underlies neuronal dysfunction in Alzheimer's disease. Free Radical Biology and Medicine, 134, pp. 468-483. (doi: 10.1016/j.freeradbiomed.2019.01.025) (PMID:30716433)

2018

Steinert, J. R. and Bourgognon, J.-M. (2018) The metabolome identity: basis for discovery of biomarkers in neurodegeneration. Neural Regeneration Research, 14(3), pp. 387-390. (doi: 10.4103/1673-5374.245464) (PMID:30539802) (PMCID:PMC6334598)

Bourgognon, J.-M. , Spiers, J. G., Scheiblich, H., Antonov, A., Bradley, S. J. , Tobin, A. B. and Steinert, J. R. (2018) Alterations in neuronal metabolism contribute to the pathogenesis of prion disease. Cell Death and Differentiation, 25(8), pp. 1408-1425. (doi: 10.1038/s41418-018-0148-x) (PMID:29915278) (PMCID:PMC6113283)

Robinson, S. W. et al. (2018) Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability. PLoS Biology, 16(4), e2003611. (doi: 10.1371/journal.pbio.2003611) (PMID:29630591) (PMCID:PMC5890968)

2017

Bradley, S. J. et al. (2017) M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss. Journal of Clinical Investigation, 127(2), pp. 487-499. (doi: 10.1172/JCI87526) (PMID:27991860) (PMCID:PMC5272187)

2016

Butcher, A. J. et al. (2016) An antibody biosensor establishes the activation of the M1 muscarinic acetylcholine receptor during learning and memory. Journal of Biological Chemistry, 291(17), pp. 8862-8875. (doi: 10.1074/jbc.M115.681726) (PMID:26826123) (PMCID:PMC4861454)

Bradley, S. J. et al. (2016) Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction. Proceedings of the National Academy of Sciences of the United States of America, 113(16), pp. 4524-4529. (doi: 10.1073/pnas.1521706113) (PMID:27071102) (PMCID:PMC4843461)

2013

Bourgognon, J.-M. et al. (2013) Regulation of neuronal plasticity and fear by a dynamic change in PAR1–G protein coupling in the amygdala. Molecular Psychiatry, 18(10), pp. 1136-1145. (doi: 10.1038/mp.2012.133) (PMID:23032873) (PMCID:PMC3690134)

2011

Attwood, B. K. et al. (2011) Neuropsin cleaves EphB2 in the amygdala to control anxiety. Nature, 473(7347), pp. 372-375. (doi: 10.1038/nature09938) (PMID:21508957) (PMCID:PMC3145099)

2010

Poulin, B. et al. (2010) The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner. Proceedings of the National Academy of Sciences of the United States of America, 107(20), pp. 9440-9445. (doi: 10.1073/pnas.0914801107) (PMID:20439723) (PMCID:PMC2889095)

This list was generated on Fri Apr 26 15:34:45 2024 BST.
Jump to: Articles | Book Sections
Number of items: 14.

Articles

Spiers, J. G., Cortina Chen, H.-J., Barry, T. L., Bourgognon, J.-M. and Steinert, J. R. (2022) Redox stress and metal dys-homeostasis appear as hallmarks of early prion disease pathogenesis in mice. Free Radical Biology and Medicine, 192, pp. 182-190. (doi: 10.1016/j.freeradbiomed.2022.09.025) (PMID:36170956)

Bourgognon, J.-M. , Spiers, J. G., Robinson, S. W., Scheiblich, H., Glynn, P., Ortori, C., Bradley, S. J. , Tobin, A. B. and Steinert, J. R. (2021) Inhibition of neuroinflammatory nitric oxide signaling suppresses glycation and prevents neuronal dysfunction in mouse prion disease. Proceedings of the National Academy of Sciences of the United States of America, 118(10), e200957911. (doi: 10.1073/pnas.2009579118) (PMID:33653950)

Bourgognon, J.-M. and Cavanagh, J. (2020) The role of cytokines in modulating learning and memory and brain plasticity. Brain and Neuroscience Advances, 4, pp. 1-13. (doi: 10.1177/2398212820979802) (PMID:33415308) (PMCID:PMC7750764)

Spiers, J. G., Chen, H.-J. C., Bourgognon, J.-M. and Steinert, J. R. (2019) Dysregulation of stress systems and nitric oxide signaling underlies neuronal dysfunction in Alzheimer's disease. Free Radical Biology and Medicine, 134, pp. 468-483. (doi: 10.1016/j.freeradbiomed.2019.01.025) (PMID:30716433)

Steinert, J. R. and Bourgognon, J.-M. (2018) The metabolome identity: basis for discovery of biomarkers in neurodegeneration. Neural Regeneration Research, 14(3), pp. 387-390. (doi: 10.4103/1673-5374.245464) (PMID:30539802) (PMCID:PMC6334598)

Bourgognon, J.-M. , Spiers, J. G., Scheiblich, H., Antonov, A., Bradley, S. J. , Tobin, A. B. and Steinert, J. R. (2018) Alterations in neuronal metabolism contribute to the pathogenesis of prion disease. Cell Death and Differentiation, 25(8), pp. 1408-1425. (doi: 10.1038/s41418-018-0148-x) (PMID:29915278) (PMCID:PMC6113283)

Robinson, S. W. et al. (2018) Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability. PLoS Biology, 16(4), e2003611. (doi: 10.1371/journal.pbio.2003611) (PMID:29630591) (PMCID:PMC5890968)

Bradley, S. J. et al. (2017) M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss. Journal of Clinical Investigation, 127(2), pp. 487-499. (doi: 10.1172/JCI87526) (PMID:27991860) (PMCID:PMC5272187)

Butcher, A. J. et al. (2016) An antibody biosensor establishes the activation of the M1 muscarinic acetylcholine receptor during learning and memory. Journal of Biological Chemistry, 291(17), pp. 8862-8875. (doi: 10.1074/jbc.M115.681726) (PMID:26826123) (PMCID:PMC4861454)

Bradley, S. J. et al. (2016) Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction. Proceedings of the National Academy of Sciences of the United States of America, 113(16), pp. 4524-4529. (doi: 10.1073/pnas.1521706113) (PMID:27071102) (PMCID:PMC4843461)

Bourgognon, J.-M. et al. (2013) Regulation of neuronal plasticity and fear by a dynamic change in PAR1–G protein coupling in the amygdala. Molecular Psychiatry, 18(10), pp. 1136-1145. (doi: 10.1038/mp.2012.133) (PMID:23032873) (PMCID:PMC3690134)

Attwood, B. K. et al. (2011) Neuropsin cleaves EphB2 in the amygdala to control anxiety. Nature, 473(7347), pp. 372-375. (doi: 10.1038/nature09938) (PMID:21508957) (PMCID:PMC3145099)

Poulin, B. et al. (2010) The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner. Proceedings of the National Academy of Sciences of the United States of America, 107(20), pp. 9440-9445. (doi: 10.1073/pnas.0914801107) (PMID:20439723) (PMCID:PMC2889095)

Book Sections

Bourgognon, J.-M. , McColl, A., Suessmilch, M., Krishnadas, R. and Cavanagh, J. (2021) Stress, immune system and the brain. In: Textbook of Immunopsychiatry. Cambridge University Press: Cambridge, pp. 51-72. ISBN 9781108539623 (doi: 10.1017/9781108539623.004)

This list was generated on Fri Apr 26 15:34:45 2024 BST.

Teaching

I am a neuroscience lecturer teaching neuroscience to level 3 and 4 students, with an interest in methods that promote student engagement and support learning.


Dr Julie-Myrtille Bourgognon