Dr Antoine Vallatos
- Senior Lecturer in MRI Physics & Translational Imaging Biomarker Development (School of Psychology & Neuroscience)
telephone:
01413304490
email:
Antoine.Vallatos@glasgow.ac.uk
Wellcome Surgical Institute, University of Glasgow, Garscube campus, Bearsden, United Kingdom, G61 1QH G61 1QH
Research interests
My research programme aims at streamlining imaging biomarkers to the clinics by methodically addressing the challenges at the interface between on one side MRI physics & imaging and on the other biology & medicine. My work lies at the intersection of these fields, covering the development of novel MRI modalities and applied biomarkers, and the systematic validation of both the MRI measure and the biomarker.
Main research interests:
- Magnetic Resonance Imaging (preclinical & clinical)
- NMR, Diffusion & Flow MRI
- Brain Perfusion and Blood-brain barrier permeability MRI
- MRI / histology correlation
- MRI phantom design and development for validation and multi-site harmonisation
- Neuro-radiology
Main biomedical applications:
- Tumour invasion (i.e. Brain tumours)
- Neurovascular diseases (i.e. stroke, small vessel disease)
- Neonatal encephalopathy
Publications
2025
Sarwar, M. Sulaiman, Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Lau, Cher Hon, Waldman, Adam, Dimartino, Simone and Thrippleton, Michael J.
(2025)
3D-printable phantoms for quantitative dynamic contrast-enhanced MRI.
Magnetic Resonance in Medicine,
(doi: 10.1002/mrm.30595)
(PMID:40523083)
(Early Online Publication)
Paterson, Samantha, Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Graff, Camille and Holmes, William
ORCID: https://orcid.org/0000-0002-0942-215X
(2025)
Quantitative multiple boli arterial spin labeling.
Magnetic Resonance Imaging, 119,
110361.
(doi: 10.1016/j.mri.2025.110361)
(PMID:39971260)
2024
Mintoft, Alison, Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X and Robertson, Nicola J.
(2024)
Mesenchymal Stromal Cell therapy for Hypoxic Ischemic Encephalopathy: future directions for combination therapy with hypothermia and/or melatonin.
Seminars in Perinatology, 48(5),
151929.
(doi: 10.1016/j.semperi.2024.151929)
(PMID:38902120)
2023
Paterson, Samantha, Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Rodgers, Jean
ORCID: https://orcid.org/0000-0002-2093-3882 and Holmes, William M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2023)
Application of diffusion weighted multiple boli ASL to a murine model of human African trypanosomiasis.
Scientific Reports, 13,
8684.
(doi: 10.1038/s41598-023-34665-z)
(PMID:37248398)
(PMCID:PMC10227057)
2022
Quick, S. et al. (2022) Loss of the heterogeneous expression of flippase ATP11B leads to cerebral small vessel disease in a normotensive rat model. Acta Neuropathologica, 144(2), pp. 283-303. (doi: 10.1007/s00401-022-02441-4) (PMID:35635573) (PMCID:PMC9288385)
2021
Vallatos, A. et al. (2021) Adaptive manufacturing for healthcare during the COVID-19 emergency and beyond. Frontiers in Medical Technology, 3, 702526. (doi: 10.3389/fmedt.2021.702526) (PMID:35047941) (PMCID:PMC8757720)
Al-Mubarak, Haitham F.I., Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X and Holmes, William M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2021)
Impact of turbulence-induced asymmetric propagators on the accuracy of phase-contrast velocimetry.
Journal of Magnetic Resonance, 325,
106929.
(doi: 10.1016/j.jmr.2021.106929)
(PMID:33713991)
Al-mubarak, H., Vallatos, A. ORCID: https://orcid.org/0000-0002-5202-056X, Gallagher, L., Birch, J.
ORCID: https://orcid.org/0000-0001-9522-8435, Chalmers, A.J.
ORCID: https://orcid.org/0000-0002-1746-7278 and Holmes, W.M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2021)
Evaluating potential of multi-parametric MRI using co-registered histology: Application to a mouse model of glioblastoma.
Magnetic resonance imaging, 85,
pp. 121-127.
(doi: 10.1016/j.mri.2021.10.030)
(PMID:34687852)
2019
Al-Mubarak, H., Vallatos, A. ORCID: https://orcid.org/0000-0002-5202-056X, Gallagher, L., Birch, J.
ORCID: https://orcid.org/0000-0001-9522-8435, Gilmour, L., Foster, J., Chalmers, A.J.
ORCID: https://orcid.org/0000-0002-1746-7278 and Holmes, W.M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2019)
Stacked in-plane histology for quantitative validation of non-invasive imaging biomarkers: application to an infiltrative brain tumour model.
Journal of Neuroscience Methods, 326,
108372.
(doi: 10.1016/j.jneumeth.2019.108372)
(PMID:31348965)
Vallatos, A. ORCID: https://orcid.org/0000-0002-5202-056X, Al-Mubarak, H.F.I., Birch, J.L.
ORCID: https://orcid.org/0000-0001-9522-8435, Gallagher, L., Mullin, J.M., Gilmour, L., Holmes, W.M.
ORCID: https://orcid.org/0000-0002-0942-215X and Chalmers, A.J.
ORCID: https://orcid.org/0000-0002-1746-7278
(2019)
Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region.
Journal of Magnetic Resonance Imaging, 50(2),
pp. 529-540.
(doi: 10.1002/jmri.26580)
(PMID:30569620)
Arroja, M.M.C., Reid, E. ORCID: https://orcid.org/0000-0002-2555-438X, Roy, L.A., Vallatos, A.V.
ORCID: https://orcid.org/0000-0002-5202-056X, Holmes, W.M.
ORCID: https://orcid.org/0000-0002-0942-215X, Nicklin, S.A.
ORCID: https://orcid.org/0000-0002-9691-6210, Work, L.M.
ORCID: https://orcid.org/0000-0002-6462-4109 and McCabe, C.
ORCID: https://orcid.org/0000-0003-3111-031X
(2019)
Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion.
Scientific Reports, 9,
3154.
(doi: 10.1038/s41598-019-39102-8)
(PMID:30816157)
(PMCID:PMC6395816)
2018
Birch, J. L. et al. (2018) A novel small-molecule inhibitor of MRCK prevents radiation-driven invasion in glioblastoma. Cancer Research, 78(22), pp. 6509-6522. (doi: 10.1158/0008-5472.CAN-18-1697) (PMID:30279244)
Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Al Mubarak, Haitham F.I., Mullin, James M. and Holmes, William M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2018)
Accuracy of phase-contrast velocimetry in systems with skewed intravoxel velocity distributions.
Journal of Magnetic Resonance, 296,
pp. 121-129.
(doi: 10.1016/j.jmr.2018.09.002)
(PMID:30245475)
Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Shukla, Matsyendra Nath, Mullin, James M., Phoenix, Vernon R.
ORCID: https://orcid.org/0000-0002-8682-5200 and Holmes, William M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2018)
The effect of displacement distribution asymmetry on the accuracy of phase-shift velocimetry in porous media.
Microporous and Mesoporous Materials, 269,
pp. 130-133.
(doi: 10.1016/j.micromeso.2017.11.048)
Holmes, William M. ORCID: https://orcid.org/0000-0002-0942-215X, Vallatos, Antoine
ORCID: https://orcid.org/0000-0002-5202-056X, Gilmour, Lesley and Chalmers, Anthony J.
ORCID: https://orcid.org/0000-0002-1746-7278
(2018)
Multiple boli arterial spin labelling for high signal-to-noise rodent brain perfusion imaging.
Magnetic Resonance in Medicine, 79(2),
pp. 1020-1030.
(doi: 10.1002/mrm.26706)
(PMID:28516482)
2016
Shukla, Matsyendra Nath, Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Phoenix, Vernon R.
ORCID: https://orcid.org/0000-0002-8682-5200 and Holmes, William M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2016)
Accurate phase-shift velocimetry in rock.
Journal of Magnetic Resonance, 267,
pp. 43-53.
(doi: 10.1016/j.jmr.2016.04.006)
(PMID:27111139)
2015
Vallatos, A. ORCID: https://orcid.org/0000-0002-5202-056X, Kirsch, R.M., Williams, R.A., Hammond, R.B., Jia, X., Bröckel, U. and Britton, M.M
(2015)
Probing composition and molecular mobility in thin spherical films using nuclear magnetic resonance measurements of diffusion.
Industrial and Engineering Chemistry Research, 54(26),
pp. 6825-6830.
(doi: 10.1021/acs.iecr.5b01700)
2013
Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Evans, Rhys, Thompson, Barnaby W., Taylor, Annette F. and Britton, Melanie M.
(2013)
Chemical patterns in translating vortices: Inter- and intra-cellular mixing effects.
Chaos: An Interdisciplinary Journal of Nonlinear Science, 23(2),
023115.
(doi: 10.1063/1.4807619)
2012
Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Wilson, Mark C.T., Taylor, Annette F. and Britton, Melanie M.
(2012)
Characterising stationary and translating vortex flow using magnetic resonance.
Europhysics Letters, 99(6),
p. 68001.
(doi: 10.1209/0295-5075/99/68001)
Articles
Sarwar, M. Sulaiman, Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Lau, Cher Hon, Waldman, Adam, Dimartino, Simone and Thrippleton, Michael J.
(2025)
3D-printable phantoms for quantitative dynamic contrast-enhanced MRI.
Magnetic Resonance in Medicine,
(doi: 10.1002/mrm.30595)
(PMID:40523083)
(Early Online Publication)
Paterson, Samantha, Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Graff, Camille and Holmes, William
ORCID: https://orcid.org/0000-0002-0942-215X
(2025)
Quantitative multiple boli arterial spin labeling.
Magnetic Resonance Imaging, 119,
110361.
(doi: 10.1016/j.mri.2025.110361)
(PMID:39971260)
Mintoft, Alison, Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X and Robertson, Nicola J.
(2024)
Mesenchymal Stromal Cell therapy for Hypoxic Ischemic Encephalopathy: future directions for combination therapy with hypothermia and/or melatonin.
Seminars in Perinatology, 48(5),
151929.
(doi: 10.1016/j.semperi.2024.151929)
(PMID:38902120)
Paterson, Samantha, Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Rodgers, Jean
ORCID: https://orcid.org/0000-0002-2093-3882 and Holmes, William M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2023)
Application of diffusion weighted multiple boli ASL to a murine model of human African trypanosomiasis.
Scientific Reports, 13,
8684.
(doi: 10.1038/s41598-023-34665-z)
(PMID:37248398)
(PMCID:PMC10227057)
Quick, S. et al. (2022) Loss of the heterogeneous expression of flippase ATP11B leads to cerebral small vessel disease in a normotensive rat model. Acta Neuropathologica, 144(2), pp. 283-303. (doi: 10.1007/s00401-022-02441-4) (PMID:35635573) (PMCID:PMC9288385)
Vallatos, A. et al. (2021) Adaptive manufacturing for healthcare during the COVID-19 emergency and beyond. Frontiers in Medical Technology, 3, 702526. (doi: 10.3389/fmedt.2021.702526) (PMID:35047941) (PMCID:PMC8757720)
Al-Mubarak, Haitham F.I., Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X and Holmes, William M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2021)
Impact of turbulence-induced asymmetric propagators on the accuracy of phase-contrast velocimetry.
Journal of Magnetic Resonance, 325,
106929.
(doi: 10.1016/j.jmr.2021.106929)
(PMID:33713991)
Al-mubarak, H., Vallatos, A. ORCID: https://orcid.org/0000-0002-5202-056X, Gallagher, L., Birch, J.
ORCID: https://orcid.org/0000-0001-9522-8435, Chalmers, A.J.
ORCID: https://orcid.org/0000-0002-1746-7278 and Holmes, W.M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2021)
Evaluating potential of multi-parametric MRI using co-registered histology: Application to a mouse model of glioblastoma.
Magnetic resonance imaging, 85,
pp. 121-127.
(doi: 10.1016/j.mri.2021.10.030)
(PMID:34687852)
Al-Mubarak, H., Vallatos, A. ORCID: https://orcid.org/0000-0002-5202-056X, Gallagher, L., Birch, J.
ORCID: https://orcid.org/0000-0001-9522-8435, Gilmour, L., Foster, J., Chalmers, A.J.
ORCID: https://orcid.org/0000-0002-1746-7278 and Holmes, W.M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2019)
Stacked in-plane histology for quantitative validation of non-invasive imaging biomarkers: application to an infiltrative brain tumour model.
Journal of Neuroscience Methods, 326,
108372.
(doi: 10.1016/j.jneumeth.2019.108372)
(PMID:31348965)
Vallatos, A. ORCID: https://orcid.org/0000-0002-5202-056X, Al-Mubarak, H.F.I., Birch, J.L.
ORCID: https://orcid.org/0000-0001-9522-8435, Gallagher, L., Mullin, J.M., Gilmour, L., Holmes, W.M.
ORCID: https://orcid.org/0000-0002-0942-215X and Chalmers, A.J.
ORCID: https://orcid.org/0000-0002-1746-7278
(2019)
Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region.
Journal of Magnetic Resonance Imaging, 50(2),
pp. 529-540.
(doi: 10.1002/jmri.26580)
(PMID:30569620)
Arroja, M.M.C., Reid, E. ORCID: https://orcid.org/0000-0002-2555-438X, Roy, L.A., Vallatos, A.V.
ORCID: https://orcid.org/0000-0002-5202-056X, Holmes, W.M.
ORCID: https://orcid.org/0000-0002-0942-215X, Nicklin, S.A.
ORCID: https://orcid.org/0000-0002-9691-6210, Work, L.M.
ORCID: https://orcid.org/0000-0002-6462-4109 and McCabe, C.
ORCID: https://orcid.org/0000-0003-3111-031X
(2019)
Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion.
Scientific Reports, 9,
3154.
(doi: 10.1038/s41598-019-39102-8)
(PMID:30816157)
(PMCID:PMC6395816)
Birch, J. L. et al. (2018) A novel small-molecule inhibitor of MRCK prevents radiation-driven invasion in glioblastoma. Cancer Research, 78(22), pp. 6509-6522. (doi: 10.1158/0008-5472.CAN-18-1697) (PMID:30279244)
Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Al Mubarak, Haitham F.I., Mullin, James M. and Holmes, William M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2018)
Accuracy of phase-contrast velocimetry in systems with skewed intravoxel velocity distributions.
Journal of Magnetic Resonance, 296,
pp. 121-129.
(doi: 10.1016/j.jmr.2018.09.002)
(PMID:30245475)
Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Shukla, Matsyendra Nath, Mullin, James M., Phoenix, Vernon R.
ORCID: https://orcid.org/0000-0002-8682-5200 and Holmes, William M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2018)
The effect of displacement distribution asymmetry on the accuracy of phase-shift velocimetry in porous media.
Microporous and Mesoporous Materials, 269,
pp. 130-133.
(doi: 10.1016/j.micromeso.2017.11.048)
Holmes, William M. ORCID: https://orcid.org/0000-0002-0942-215X, Vallatos, Antoine
ORCID: https://orcid.org/0000-0002-5202-056X, Gilmour, Lesley and Chalmers, Anthony J.
ORCID: https://orcid.org/0000-0002-1746-7278
(2018)
Multiple boli arterial spin labelling for high signal-to-noise rodent brain perfusion imaging.
Magnetic Resonance in Medicine, 79(2),
pp. 1020-1030.
(doi: 10.1002/mrm.26706)
(PMID:28516482)
Shukla, Matsyendra Nath, Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Phoenix, Vernon R.
ORCID: https://orcid.org/0000-0002-8682-5200 and Holmes, William M.
ORCID: https://orcid.org/0000-0002-0942-215X
(2016)
Accurate phase-shift velocimetry in rock.
Journal of Magnetic Resonance, 267,
pp. 43-53.
(doi: 10.1016/j.jmr.2016.04.006)
(PMID:27111139)
Vallatos, A. ORCID: https://orcid.org/0000-0002-5202-056X, Kirsch, R.M., Williams, R.A., Hammond, R.B., Jia, X., Bröckel, U. and Britton, M.M
(2015)
Probing composition and molecular mobility in thin spherical films using nuclear magnetic resonance measurements of diffusion.
Industrial and Engineering Chemistry Research, 54(26),
pp. 6825-6830.
(doi: 10.1021/acs.iecr.5b01700)
Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Evans, Rhys, Thompson, Barnaby W., Taylor, Annette F. and Britton, Melanie M.
(2013)
Chemical patterns in translating vortices: Inter- and intra-cellular mixing effects.
Chaos: An Interdisciplinary Journal of Nonlinear Science, 23(2),
023115.
(doi: 10.1063/1.4807619)
Vallatos, Antoine ORCID: https://orcid.org/0000-0002-5202-056X, Wilson, Mark C.T., Taylor, Annette F. and Britton, Melanie M.
(2012)
Characterising stationary and translating vortex flow using magnetic resonance.
Europhysics Letters, 99(6),
p. 68001.
(doi: 10.1209/0295-5075/99/68001)