Dr Monica Tsimbouri
- Research Technologist (Molecular Biosciences)
telephone:
01413307555
email:
Penelope.Tsimbouri@glasgow.ac.uk
room 492,, Institute of MC&SB, Advanced Research Centre, (ARC), 11 Chapel Lane,, Glasgow,, G11 6EW
Research interests
Publications
2026
Doherty-Boyd, W. S. et al. (2026) Synthetic peptide hydrogels as a model of the bone marrow niche demonstrate efficacy of a combined CRISPR-CAR T-cell therapy for acute myeloid leukaemia. Biomaterials, 328, 123803. (doi: 10.1016/j.biomaterials.2025.123803) (PMID:41187596)
Bispo, D. S.C. et al. (2026) Global metabolomics identifies new extracellular biomarkers of nanovibration-driven mesenchymal stem cells osteodifferentiation. Biomaterials Advances, 180, 214567. (doi: 10.1016/j.bioadv.2025.214567) (PMID:41129959)
2025
Tsigkos, Ioannis A., Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458, Salmeron-Sanchez, Manuel
ORCID: https://orcid.org/0000-0002-8112-2100 and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2025)
Sustained growth factor release driven cellular therapy indicates enhanced potential for regeneration upon mechanical injury.
Biomaterials Advances, 177,
214389.
(doi: 10.1016/j.bioadv.2025.214389)
(PMID:40570633)
2024
Young, Peter ORCID: https://orcid.org/0000-0002-1364-9787, Greer, Andrew I.M.
ORCID: https://orcid.org/0000-0003-2817-5884, Smith, Carol-Anne
ORCID: https://orcid.org/0000-0003-3461-7407, Silverwood, Robert, Tsimbouri, Penelope M.
ORCID: https://orcid.org/0000-0001-5124-7458, Meek, Dominic, Goodyear, Carl, Gadegaard, Nikolaj
ORCID: https://orcid.org/0000-0002-3396-846X and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2024)
Titanium surface synergy: strontium incorporation and controlled disorder nanotopography optimise osteoinduction.
ACS Applied Materials and Interfaces, 16(46),
pp. 63129-63141.
(doi: 10.1021/acsami.4c04117)
(PMID:39509174)
Cuahtecontzi Delint, R. et al. (2024) Nanotopography influences host-pathogen quorum sensing and facilitates selection of bioactive metabolites in mesenchymal stromal cells and pseudomonas aeruginosa co-cultures. ACS Applied Materials and Interfaces, 16(33), pp. 43374-43386. (doi: 10.1021/acsami.4c09291) (PMID:39113638) (PMCID:PMC11345723)
Donnelly, H. et al. (2024) Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells. Nature Communications, 15, 5791. (doi: 10.1038/s41467-024-50054-0) (PMID:38987295) (PMCID:PMC11237034)
López-Laguna, H. et al. (2024) Hybrid micro-/nanoprotein platform provides endocrine-like and extracellular matrix-like cell delivery of growth factors. ACS Applied Materials and Interfaces, 16(26), pp. 32930-32944. (doi: 10.1021/acsami.4c01210) (PMID:38888932) (PMCID:PMC11231985)
Doherty-Boyd, W. Sebastian, Tsimbouri, Monica P. ORCID: https://orcid.org/0000-0001-5124-7458, Donnelly, Hannah
ORCID: https://orcid.org/0000-0002-5154-9971 and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2024)
Building bones for blood and beyond: the growing field of bone marrow niche model development.
Experimental Hematology, 135,
104232.
(doi: 10.1016/j.exphem.2024.104232)
(PMID:38729553)
Ishak, Mohd I., Cuahtecontzi Delint, Rosalia, Liu, Xiayi, Xu, Wei, Tsimbouri, Penelope M. ORCID: https://orcid.org/0000-0001-5124-7458, Nobbs, Angela H, Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Su, Bo
(2024)
Nanotextured titanium inhibits bacterial activity and supports cell growth on 2D and 3D substrate: a co-culture study.
Biomaterials Advances, 158,
213766.
(doi: 10.1016/j.bioadv.2024.213766)
(PMID:38232578)
2023
Cuahtecontzi Delint, Rosalia, Ishak, I., Tsimbouri, Monica P. ORCID: https://orcid.org/0000-0001-5124-7458, Jayawarna, Vineetha, Nobbs, A., Salmeron-Sanchez, Manuel
ORCID: https://orcid.org/0000-0002-8112-2100, Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Su, B.
(2023)
In-Vitro Studies of 2D Orthopaedic Implants with Cell Instructive Nanotopographies.
TERMIS 2023 – European Chapter, Manchester, UK, 28–31 March 2023.
(doi: 10.1089/ten.tea.2023.29043.abstract)
Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)
Donnelly, Hannah ORCID: https://orcid.org/0000-0002-5154-9971, Vermeulen, Steven, Tsimbouri, Monica
ORCID: https://orcid.org/0000-0001-5124-7458 and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2023)
Cell–material interactions.
In: De Boer, Jan and Van Blitterswijk, Clemens A. (eds.)
Tissue Engineering.
Elsevier, pp. 261-292.
ISBN 9780128244593
(doi: 10.1016/B978-0-12-824459-3.00008-1)
2022
Xiao, Yinbo, Donnelly, Hannah ORCID: https://orcid.org/0000-0002-5154-9971, Sprott, Mark
ORCID: https://orcid.org/0000-0002-1990-9498, Luo, Jiajun, Jayawarna, Vineetha, Lemgruber, Leandro
ORCID: https://orcid.org/0000-0003-2832-6806, Tsimbouri, P. Monica
ORCID: https://orcid.org/0000-0001-5124-7458, Meek, R.M. Dominic, Salmeron-Sanchez, Manuel
ORCID: https://orcid.org/0000-0002-8112-2100 and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2022)
Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis.
Materials Today Bio, 16,
100367.
(doi: 10.1016/j.mtbio.2022.100367)
(PMID:35937570)
(PMCID:PMC9352550)
Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)
2021
Kennedy, John W., Tsimbouri, Monica ORCID: https://orcid.org/0000-0001-5124-7458, Campsie, Paul, Sood, Shatakshi, Childs, Peter G., Reid, Stuart, Young, Peter S.
ORCID: https://orcid.org/0000-0002-1364-9787, Meek, Dominic R. M., Goodyear, Carl S.
ORCID: https://orcid.org/0000-0001-5926-5941 and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2021)
Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures.
Scientific Reports, 11,
22741.
(doi: 10.1038/s41598-021-02139-9)
Hodgkinson, T. et al. (2021) The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science Advances, 7(9), eabb7921. (doi: 10.1126/sciadv.abb7921) (PMID:33637520) (PMCID:PMC7909882)
2020
Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)
2018
Waddell, Shona J., de Andrés, María C., Tsimbouri, Penelope M. ORCID: https://orcid.org/0000-0001-5124-7458, Alakpa, Enateri V., Cusack, Maggie, Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Oreffo, Richard O.C.
(2018)
Biomimetic oyster shell-replicated topography alters the behaviour of human skeletal stem cells.
Journal of Tissue Engineering, 9,
p. 2041731418794007.
(doi: 10.1177/2041731418794007)
(PMID:30202512)
(PMCID:PMC6124183)
Robertson, S. N. et al. (2018) Control of cell behaviour through nanovibrational stimulation: nanokicking. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 376(2120), 20170290. (doi: 10.1098/rsta.2017.0290) (PMID:29661978) (PMCID:PMC5915650)
Orapiriyakul, Wich, Young, Peter S. ORCID: https://orcid.org/0000-0002-1364-9787, Damiati, Laila and Tsimbouri, Penelope M.
ORCID: https://orcid.org/0000-0001-5124-7458
(2018)
Antibacterial surface modification of titanium implants in orthopaedics.
Journal of Tissue Engineering, 9,
pp. 1-16.
(doi: 10.1177/2041731418789838)
(PMID:30083308)
(PMCID:PMC6071164)
Allan, Christopher, Ker, Andrew, Smith, Carol-Anne ORCID: https://orcid.org/0000-0003-3461-7407, Tsimbouri, Penelope
ORCID: https://orcid.org/0000-0001-5124-7458, Borsoi, Juliana, O'Neill, Stewart, Gadegaard, Nikolaj
ORCID: https://orcid.org/0000-0002-3396-846X, Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Meek, Dominic
(2018)
Osteoblast response to disordered nanotopography.
Journal of Tissue Engineering, 9,
pp. 1-7.
(doi: 10.1177/2041731418784098)
(PMID:30034770)
(PMCID:PMC6048666)
AlQarni, S. et al. (2018) Lymphomas driven by Epstein-Barr virus nuclear antigen-1 (EBNA1) are dependant upon Mdm2. Oncogene, 37, pp. 3998-4012. (doi: 10.1038/s41388-018-0147-x) (PMID:29691476) (PMCID:PMC6054874)
Damiati, Laila, Eales, Marcus G., Nobbs, Angela H., Su, Bo, Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458, Salmeron-Sanchez, Manuel
ORCID: https://orcid.org/0000-0002-8112-2100 and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2018)
Impact of surface topography and coating on osteogenesis and bacterial attachment on titanium implants.
Journal of Tissue Engineering, 9,
pp. 1-16.
(doi: 10.1177/2041731418790694)
(PMID:30116518)
2017
Fraioli, R. et al. (2017) Towards the cell-instructive bactericidal substrate: exploring the combination of nanotopographical features and integrin selective synthetic ligands. Scientific Reports, 7, 16363. (doi: 10.1038/s41598-017-16385-3) (PMID:29180787) (PMCID:PMC5703844)
Thomson, Suzanne E., Charalambous, Chloe, Smith, Carol-Anne ORCID: https://orcid.org/0000-0003-3461-7407, Tsimbouri, Penelope M.
ORCID: https://orcid.org/0000-0001-5124-7458, Déjardin, Theophile, Kingham, Paul J., Hart, Andrew M. and Riehle, Mathis O.
ORCID: https://orcid.org/0000-0001-7988-1514
(2017)
Microtopographical cues promote peripheral nerve regeneration via transient mTORC2 activation.
Acta Biomaterialia, 60,
pp. 220-231.
(doi: 10.1016/j.actbio.2017.07.031)
(PMID:28754648)
(PMCID:PMC5593812)
Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)
Anderson, H., Llopis-Hernandez, V. ORCID: https://orcid.org/0000-0002-7616-7347, Sweeten, P., Donnelly, H., Gurden, R., Orapiriyakul, W., Salmeron-Sanchez, M.
ORCID: https://orcid.org/0000-0002-8112-2100, Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Tsimbouri, M.P.
ORCID: https://orcid.org/0000-0001-5124-7458
(2017)
Nanoscale surface cues and cell behaviour.
In: Hashmi, Saleem (ed.)
Reference Module in Materials Science and Materials Engineering.
Elsevier.
ISBN 9780128035818
(doi: 10.1016/B978-0-12-803581-8.10226-7)
2016
Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Fisher, L., Holloway, N., Sjostrom, T., Meek, R.M.D., Su, B. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2016)
Osteogenic and bactericidal surfaces from hydrothermal titania nanowires on titanium substrates.
Scientific Reports, 6,
36857.
(doi: 10.1038/srep36857)
(PMID:27857168)
(PMCID:PMC5114696)
Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Holloway, N., Fisher, L., Sjostrom, T., Nobbs, A.H., Meek, R.M.D., Su, B. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2016)
Osteogenic and Bactericidal Surfaces from Hydrothermal Titania Nanowires on Titanium Substrates.
The British Orthopaedic Research Society (BORS) Annual Conference, Glasgow, UK, 5-6 Sept 2016.
Young, P.S., Greer, A.I.M. ORCID: https://orcid.org/0000-0003-2817-5884, Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458, Meek, R.M.D., Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2016)
Precision-Engineered Nanotopographical Surfaces to Control Osteoclast Differentiation.
In: The British Orthopaedic Research Society (BORS) Annual Conference, Glasgow, UK, 5-6 Sept 2016,
Llopis-Hernández, Virginia ORCID: https://orcid.org/0000-0002-7616-7347, Cantini, Marco
ORCID: https://orcid.org/0000-0003-0326-1508, González-García, Cristina, Cheng, Zhe A., Yang, Jingli, Tsimbouri, Penelope M.
ORCID: https://orcid.org/0000-0001-5124-7458, García, Andrés J., Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Salmerón-Sánchez, Manuel
ORCID: https://orcid.org/0000-0002-8112-2100
(2016)
Material-driven fibronectin assembly for high-efficiency presentation of growth factors.
Science Advances, 2(8),
e1600188.
(doi: 10.1126/sciadv.1600188)
(PMID:27574702)
(PMCID:PMC5001810)
Silverwood, R. K. et al. (2016) Analysis of osteoclastogenesis/osteoblastogenesis on nanotopographical titania surfaces. Advanced Healthcare Materials, 5(8), pp. 947-955. (doi: 10.1002/adhm.201500664) (PMID:26890261)
Adekanmbi, Isaiah, Ferguson, Louisa, Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Riehle, Mathis
ORCID: https://orcid.org/0000-0001-7988-1514, Kubba, Haytham and Tanner, K.E.
ORCID: https://orcid.org/0000-0003-2257-0218
(2016)
Evaluation of Cell Viability of Biodegradable AZ31 Mg Alloy for Use in Paediatric Tracheal Stent after Long Term In Vitro Corrosion.
In: 10th World Biomaterials Congress, Montreal, Canada, 17-22 May 2016,
(doi: 10.3389/conf.FBIOE.2016.01.02513)
2015
Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458
(2015)
Adult stem cell responses to nanostimuli.
Journal of Functional Biomaterials, 6(3),
pp. 598-622.
(doi: 10.3390/jfb6030598)
(PMID:26193326)
(PMCID:PMC4598673)
Pemberton, Gabriel D., Childs, Peter, Reid, Stuart, Nikukar, Habib, Tsimbouri, Monica ORCID: https://orcid.org/0000-0001-5124-7458, Gadegaard, Nikolaj
ORCID: https://orcid.org/0000-0002-3396-846X, Curtis, Adam SG and Dalby, Matthew J
ORCID: https://orcid.org/0000-0002-0528-3359
(2015)
Nanoscale stimulation of osteoblastogenesis from mesenchymal stem cells: nanotopography and nanokicking.
Nanomedicine, 10(4),
pp. 547-560.
(doi: 10.2217/nnm.14.134)
(PMID:25723089)
Tsimbouri, Penelope M. ORCID: https://orcid.org/0000-0001-5124-7458, McNamara, Laura E., Alakpa, Enateri V., Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Turner, Lesley-Anne
(2015)
Cell material interactions.
In: van Blitterswijk, Clemens A. and de Boer, Jan (eds.)
Tissue Engineering.
Elsevier, pp. 217-251.
ISBN 9780124202108
(doi: 10.1016/B978-0-12-420145-3.00007-9)
Young, P.S., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X, Meek, R.M.D. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2015)
Osteoclastogenesis/osteoblastogenesis using human bone marrow-derived cocultures on nanotopographical polymer surfaces.
Nanomedicine, 10(6),
pp. 949-957.
(doi: 10.2217/nnm.14.146)
(PMID:25867859)
2014
Thomson, Suzanne E., Déjardin, Theo, Tsimbouri, Monica P. ORCID: https://orcid.org/0000-0001-5124-7458, Hart, Andrew M. and Riehle, Mathis O.
ORCID: https://orcid.org/0000-0001-7988-1514
(2014)
Combinational approaches to improve outcomes following peripheral nerve repair.
Journal of Plastic, Reconstructive and Aesthetic Surgery, 67(10),
p. 1465.
(doi: 10.1016/j.bjps.2014.08.032)
Curtis, Adam S and Tsimbouri, Penelope M ORCID: https://orcid.org/0000-0001-5124-7458
(2014)
Epigenesis: roles of nanotopography, nanoforces and nanovibration.
Expert Review of Medical Devices, 11(4),
pp. 417-423.
(doi: 10.1586/17434440.2014.916205)
McMurray, Rebecca J., Dalby, Matthew ORCID: https://orcid.org/0000-0002-0528-3359 and Tsimbouri, P. Monica
ORCID: https://orcid.org/0000-0001-5124-7458
(2014)
Using biomaterials to study stem cell mechanotransduction, growth and differentiation.
Journal of Tissue Engineering and Regenerative Medicine, 9(5),
pp. 528-539.
(doi: 10.1002/term.1957)
(PMID:25370612)
Silverwood, R.K., Fairhurst, P., Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Sjostrom, T., Young, P., Su, B., Meek, R.M.D. and Dalby, M.
ORCID: https://orcid.org/0000-0002-0528-3359
(2014)
Analysis of Osteoclastogenesis/Osteoblastogenesis Using Human Bone Marrow Derived Co-Cultures on Nanotopographical Titania Surfaces.
In: Glasgow Meeting of Orthopaedic Research (GLAMOR), Glasgow, UK, 28 Mar 2014,
Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Gadegaard, N., Burgess, K., White, K., Reynolds, P.
ORCID: https://orcid.org/0000-0001-7614-0008, Herzyk, P.
ORCID: https://orcid.org/0000-0002-7439-292X, Oreffo, R. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2014)
Nanotopographical effects on mesenchymal stem cell morphology and phenotype.
Journal of Cellular Biochemistry, 115(2),
pp. 380-390.
(doi: 10.1002/jcb.24673)
(PMID:24123223)
McNamara, Laura E., Dalby, Matthew J. ORCID: https://orcid.org/0000-0002-0528-3359 and Tsimbouri, Monica P.
ORCID: https://orcid.org/0000-0001-5124-7458
(2014)
The use of microarrays and fluorescence in situ hybridization for the study of mechanotransduction from topography.
Methods in Cell Biology, 119,
pp. 293-309.
(doi: 10.1016/B978-0-12-416742-1.00015-9)
(PMID:24439291)
2013
Seras-Franzoso, J., Peebo, K., Corchero, J.L., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Unzueta, U., Rinas, U., Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359, Vazquez, E., García-Fruitós, E. and Villaverde, A.
(2013)
A nanostructured bacterial bioscaffold for the sustained bottom-up delivery of protein drugs.
Nanomedicine, 8(10),
pp. 1587-1599.
(doi: 10.2217/nnm.12.188)
Herd, J.M., Joseph, J., McGarvey, M., Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Bennett, A., Meek, R.M.D. and Morrison, A.
(2013)
Intra-Operative Cell Salvage in Revision Hip Surgery.
In: Glasgow Meeting of Orthopaedic Research (GLAMOR), Glasgow, 2013,
Nikukar, H., Reid, S.W.J., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Riehle, M.O.
ORCID: https://orcid.org/0000-0001-7988-1514, Curtis, A.S.G. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2013)
Osteogenesis of mesenchymal stem cells by nanoscale mechanotransduction.
ACS Nano, 7(3),
pp. 2758-2767.
(doi: 10.1021/nn400202j)
Wiejak, Jolanta, Tsimbouri, Penelope M. ORCID: https://orcid.org/0000-0001-5124-7458, Herzyk, Pawel
ORCID: https://orcid.org/0000-0002-7439-292X, Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359, Hamilton, Graham and Yarwood, Stephen J.
(2013)
Genomic analysis of the role of transcription factor C/EBPδ in the regulation of cell behaviour on nanometric grooves.
Biomaterials, 34(8),
pp. 1967-1979.
(doi: 10.1016/j.biomaterials.2012.11.036)
(PMID:23245923)
(PMCID:PMC3543902)
Tsimbouri, Penelope M. ORCID: https://orcid.org/0000-0001-5124-7458, Murawski, Kate, Hamilton, Graham, Herzyk, Pawel
ORCID: https://orcid.org/0000-0002-7439-292X, Oreffo, Richard O.C., Gadegaard, Nikolaj
ORCID: https://orcid.org/0000-0002-3396-846X and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2013)
A genomics approach in determining nanotopographical effects on MSC phenotype.
Biomaterials, 34(9),
pp. 2177-2184.
(doi: 10.1016/j.biomaterials.2012.12.019)
(PMID:23312853)
(PMCID:PMC3573234)
Seras-Franzoso, J., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Burgess, K.V., Unzueta, U., Garcia-Fruitos, E., Vazquez, E., Villaverde, A. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2013)
Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces.
Nanomedicine, 9(2),
pp. 207-220.
(doi: 10.2217/nnm.13.43)
(PMID:23631503)
2012
Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, McMurray, R.J., Burgess, K.V., Alakpa, E.V., Reynolds, Paul
ORCID: https://orcid.org/0000-0001-7614-0008, Murawski, K., Kingham, E., Oreffo, R.O.C., Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2012)
Using nanotopography and metabolomics to identify biochemical effectors of multipotency.
ACS Nano, 6(11),
pp. 10239-10249.
(doi: 10.1021/nn304046m)
Dalby, M.J. ORCID: https://orcid.org/0000-0002-0528-3359, Macintyre, A., Roberts, J.N.
ORCID: https://orcid.org/0000-0002-8926-1041, Yang, J., Lee, L.C.Y., Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458 and McNamara, L.E.
(2012)
Nanosubstrates to illustrate differential adhesion mechanisms to fibronectin and vitronectin.
Nanomedicine, 7(1),
pp. 17-21.
(doi: 10.2217/nnm.11.172)
Dalby, M.J. ORCID: https://orcid.org/0000-0002-0528-3359, Macintyre, A., Roberts, J.N., Yang, J., Lee, L..L.C.Y., Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458 and McNamara, L.E.
(2012)
3D patterned agarose hydrogels for investigation of precursor cells in differentiation and chemoattraction.
Nanomedicine, 7(1),
pp. 17-21.
(doi: 10.2217/nnm.11.172)
Dalby, M.J. ORCID: https://orcid.org/0000-0002-0528-3359, Macintyre, A., Roberts, J.N., Yang, J., Lee, L.C.Y., Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458 and McNamara, L.E.
(2012)
Nanoporous titanium substrates for osteogenesis.
Nanomedicine, 7(1),
pp. 17-21.
(doi: 10.2217/nnm.11.172)
Dalby, M.J. ORCID: https://orcid.org/0000-0002-0528-3359, Macintyre, A., Roberts, J.N., Yang, J., Lee, L.C.Y., Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458 and McNamara, L.E.
(2012)
Research Highlights.
Nanomedicine, 7(1),
pp. 17-21.
(doi: 10.2217/nnm.11.172)
2011
McMurray, R.J., Gadegaard, N. ORCID: https://orcid.org/0000-0002-3396-846X, Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458, Burgess, K.V., McNamara, L.E., Tare, R., Murawski, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2011)
Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency.
Nature Materials, 10(8),
pp. 637-644.
(doi: 10.1038/nmat3058)
(PMID:21765399)
Kingham, E.J., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X, Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Oreffo, R.O.C.
(2011)
Nanotopography induced osteogenic differentiation of human stem cells.
Bone, 48(Sup. 2),
S108-S109.
(doi: 10.1016/j.bone.2011.03.177)
Hannigan, A., Qureshi, A.M., Nixon, C., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Jones, S., Philbey, A.W. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2011)
Lymphocyte deficiency limits Epstein-Barr virus latent membrane protein 1 induced chronic inflammation and carcinogenic pathology in vivo.
Molecular Cancer, 10(11),
pp. 1-20.
(doi: 10.1186/1476-4598-10-11)
Khokhar, A.Z., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X
(2011)
Development of ultra-hard stamps for titanium patterning.
In: 37th International Conference on Micro and Nano Engineering: MNE 2011, Berlin, 19 - 23 September 2011,
McNamara, L.E., McMurray, R.J., Dalby, M.J. ORCID: https://orcid.org/0000-0002-0528-3359 and Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458
(2011)
Surfaces and Cell Behavior.
Comprehensive Biomaterials, 4(409),
pp. 115-126.
(doi: 10.1016/B978-0-08-055294-1.00010-6)
Nokhbatolfoghahai, M., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Wilson, J.B. and Downie, J.R.
(2011)
Evolutionary analysis of genes involved in cement gland development in anurans.
Iranian Journal of Science and Technology, A3,
Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X, Burgess, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2011)
Mechanotransduction and skeletal stem cell differentiation in response to bioactive nanotopography.
Histology and Histopathology: Cellular and Molecular Biology, 26(S1),
31.012.
Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X, Oreffo, R.O.C. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2011)
Effects of nanotopography on cell adhesion, morphology and differentiation.
European Cells and Materials, 22(S2),
p. 14.
2010
McMurray, R.J., Gadegaard, N. ORCID: https://orcid.org/0000-0002-3396-846X, Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359, Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458, Maclaine, S., Meek, D., McNamara, L.E., Child, H. and Berry, C.C.
ORCID: https://orcid.org/0000-0002-6485-2187
(2010)
Research highlights.
Nanomedicine, 5(10),
pp. 1495-1499.
(doi: 10.2217/nnm.10.119)
Repellin, C.E, Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Philbey, A.W. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2010)
Lymphoid hyperplasia and lymphoma in transgenic mice expressing the small non-coding RNA, EBER1 of Epstein-Barr virus.
PLoS ONE, 5(2),
e9092.
(doi: 10.1371/journal.pone.0009092)
(PMID:20161707)
(PMCID:PMC2817001)
2009
Rossi, L., Riehle, M.O. ORCID: https://orcid.org/0000-0001-7988-1514, McNamara, L.E., Burchmore, R.
ORCID: https://orcid.org/0000-0003-1663-9004, Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359, McMurray, R.J., Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X, Ahmed, S. and Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458
(2009)
Research highlights.
Nanomedicine, 4(6),
pp. 613-617.
(doi: 10.2217/nnm.09.46)
2008
McLean, Adele, Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458 and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2008)
Massive Overexpression of Chitnase3-like 4 (YM2), CD30 and Immunoglobulin in LMP1 Induced Inflammation Associated Carcinogenesis.
13th International EBV Symposium, Guangzgou, China, 7-10 Nov 2008.
Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458, Chiou, Yih-Chy and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2008)
EBERs the Small Viral Non-coding RNAs are Tumourigenic and Disturb the Interferon Response in Vivo.
Beatson International Cancer Conference Cell Growth and Metabolism, Glasgow, UK, 15-18 Jun 2008.
Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Al-Sheikh, Y., Drotar, M. E., Cushley, W. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2008)
Epstein-Barr virus nuclear antigen-1 renders lymphocytes responsive to IL-2 but not IL-15 for survival.
Journal of General Virology, 89(11),
pp. 2821-2832.
(doi: 10.1099/vir.0.83296-0)
2007
Chiou, Yih-Chy, Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458 and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2007)
EBER1 – a Small Viral Non-coding RNA is Tumourigenic and Disturbs the Interferon Response in Vivo.
Beatson International Cancer Conference, Glasgow, UK, 16-20 Jun 2007.
Charalambous, C.T., Hannigan, A., Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, McPhee, G.M. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2007)
Latent membrane protein 1-induced EGFR signalling is negatively regulated by TGF prior to neoplasia.
Carcinogenesis, 28(8),
pp. 1839-1848.
(doi: 10.1093/carcin/bgm055)
2006
Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458, Al-Sheikh, Yazeed, Mclean, Adele, Drotar, Mark and Wilson, Joanna B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2006)
An Evaluation of the Contribution of EBNA1 Expression to Transgenic Mouse Lymphomagenesis.
12th International EBV Symposium, Boston, MA, USA, 08-12 Jul 2006.
2005
Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458 and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2005)
A viral oncogene which induces B-cells to survive in response to IL-2.
Experimental Hematology, 33(S7),
p. 112.
(doi: 10.1016/j.exphem.2005.05.017)
2004
Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458, Drotar, Mark, Hill, E. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2004)
EBNA1 Induces B-cells to Respond to IL-2 Survival Signals.
11th International EBV Symposium, Regensberg, Germany, 20-25 Sep 2004.
2003
Drotar, M.E., Silva, S., Barone, E., Campbell, D., Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Jurvansu, J., Bhatia, P., Klein, G. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2003)
Epstein-Barr virus nuclear antigen-1 and Myc cooperate in lymphomagenesis.
International Journal of Cancer, 106,
pp. 388-395.
(doi: 10.1002/ijc.11224)
(PMID:12845679)
2002
Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458 and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2002)
The Action of EBNA1 as an Oncogene in Vivo.
10th International Symposium on Epstein-Barr Virus and Associated Malignant Diseases, Cairns, Australia, 16-21 Jul 2002.
Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Drotar, M.E., Coy, J.L. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2002)
bcl-x(L) and RAG genes are induced and the response to IL-2 enhanced in E mu EBNA-1 transgenic mouse lymphocytes.
Oncogene, 21,
pp. 5182-5187.
(doi: 10.1038/sj.onc.1205490)
2001
Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, O'Donnell, M.A. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2001)
Selection and enrichment of B cells from lymphoid tissues.
In: Wilson, J.B,. and May, G.H.W. (eds.)
Epstein-Barr Virus Protocols.
Series: Methods in Molecular Biology (174).
The Humana Press Inc.: Totowa, N.J., pp. 411-421.
ISBN 9780896036901
(doi: 10.1385/1-59259-227-9:411)
2000
Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458, Cushley, William and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2000)
EBNA1 Mechanism of Action as an Oncogene.
9th Biennial Conference of the International Assoication for Research on Epstein-Barr Virus, New Haven, CT, USA, 22-27 Jun 2000.
Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458, Cushley, William and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2000)
EBNA-1 Action as an Oncogene.
10th TENOVUS Scotland Symposium: Gene Expression and Disease, Glasgow, UK, 10-12 Apr 2000.
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Building bones for blood and beyond: the growing field of bone marrow niche model development.
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Biomimetic oyster shell-replicated topography alters the behaviour of human skeletal stem cells.
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Antibacterial surface modification of titanium implants in orthopaedics.
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Osteogenic and bactericidal surfaces from hydrothermal titania nanowires on titanium substrates.
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(PMID:26193326)
(PMCID:PMC4598673)
Pemberton, Gabriel D., Childs, Peter, Reid, Stuart, Nikukar, Habib, Tsimbouri, Monica ORCID: https://orcid.org/0000-0001-5124-7458, Gadegaard, Nikolaj
ORCID: https://orcid.org/0000-0002-3396-846X, Curtis, Adam SG and Dalby, Matthew J
ORCID: https://orcid.org/0000-0002-0528-3359
(2015)
Nanoscale stimulation of osteoblastogenesis from mesenchymal stem cells: nanotopography and nanokicking.
Nanomedicine, 10(4),
pp. 547-560.
(doi: 10.2217/nnm.14.134)
(PMID:25723089)
Young, P.S., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X, Meek, R.M.D. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2015)
Osteoclastogenesis/osteoblastogenesis using human bone marrow-derived cocultures on nanotopographical polymer surfaces.
Nanomedicine, 10(6),
pp. 949-957.
(doi: 10.2217/nnm.14.146)
(PMID:25867859)
Thomson, Suzanne E., Déjardin, Theo, Tsimbouri, Monica P. ORCID: https://orcid.org/0000-0001-5124-7458, Hart, Andrew M. and Riehle, Mathis O.
ORCID: https://orcid.org/0000-0001-7988-1514
(2014)
Combinational approaches to improve outcomes following peripheral nerve repair.
Journal of Plastic, Reconstructive and Aesthetic Surgery, 67(10),
p. 1465.
(doi: 10.1016/j.bjps.2014.08.032)
Curtis, Adam S and Tsimbouri, Penelope M ORCID: https://orcid.org/0000-0001-5124-7458
(2014)
Epigenesis: roles of nanotopography, nanoforces and nanovibration.
Expert Review of Medical Devices, 11(4),
pp. 417-423.
(doi: 10.1586/17434440.2014.916205)
McMurray, Rebecca J., Dalby, Matthew ORCID: https://orcid.org/0000-0002-0528-3359 and Tsimbouri, P. Monica
ORCID: https://orcid.org/0000-0001-5124-7458
(2014)
Using biomaterials to study stem cell mechanotransduction, growth and differentiation.
Journal of Tissue Engineering and Regenerative Medicine, 9(5),
pp. 528-539.
(doi: 10.1002/term.1957)
(PMID:25370612)
Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Gadegaard, N., Burgess, K., White, K., Reynolds, P.
ORCID: https://orcid.org/0000-0001-7614-0008, Herzyk, P.
ORCID: https://orcid.org/0000-0002-7439-292X, Oreffo, R. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2014)
Nanotopographical effects on mesenchymal stem cell morphology and phenotype.
Journal of Cellular Biochemistry, 115(2),
pp. 380-390.
(doi: 10.1002/jcb.24673)
(PMID:24123223)
McNamara, Laura E., Dalby, Matthew J. ORCID: https://orcid.org/0000-0002-0528-3359 and Tsimbouri, Monica P.
ORCID: https://orcid.org/0000-0001-5124-7458
(2014)
The use of microarrays and fluorescence in situ hybridization for the study of mechanotransduction from topography.
Methods in Cell Biology, 119,
pp. 293-309.
(doi: 10.1016/B978-0-12-416742-1.00015-9)
(PMID:24439291)
Seras-Franzoso, J., Peebo, K., Corchero, J.L., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Unzueta, U., Rinas, U., Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359, Vazquez, E., García-Fruitós, E. and Villaverde, A.
(2013)
A nanostructured bacterial bioscaffold for the sustained bottom-up delivery of protein drugs.
Nanomedicine, 8(10),
pp. 1587-1599.
(doi: 10.2217/nnm.12.188)
Nikukar, H., Reid, S.W.J., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Riehle, M.O.
ORCID: https://orcid.org/0000-0001-7988-1514, Curtis, A.S.G. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2013)
Osteogenesis of mesenchymal stem cells by nanoscale mechanotransduction.
ACS Nano, 7(3),
pp. 2758-2767.
(doi: 10.1021/nn400202j)
Wiejak, Jolanta, Tsimbouri, Penelope M. ORCID: https://orcid.org/0000-0001-5124-7458, Herzyk, Pawel
ORCID: https://orcid.org/0000-0002-7439-292X, Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359, Hamilton, Graham and Yarwood, Stephen J.
(2013)
Genomic analysis of the role of transcription factor C/EBPδ in the regulation of cell behaviour on nanometric grooves.
Biomaterials, 34(8),
pp. 1967-1979.
(doi: 10.1016/j.biomaterials.2012.11.036)
(PMID:23245923)
(PMCID:PMC3543902)
Tsimbouri, Penelope M. ORCID: https://orcid.org/0000-0001-5124-7458, Murawski, Kate, Hamilton, Graham, Herzyk, Pawel
ORCID: https://orcid.org/0000-0002-7439-292X, Oreffo, Richard O.C., Gadegaard, Nikolaj
ORCID: https://orcid.org/0000-0002-3396-846X and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2013)
A genomics approach in determining nanotopographical effects on MSC phenotype.
Biomaterials, 34(9),
pp. 2177-2184.
(doi: 10.1016/j.biomaterials.2012.12.019)
(PMID:23312853)
(PMCID:PMC3573234)
Seras-Franzoso, J., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Burgess, K.V., Unzueta, U., Garcia-Fruitos, E., Vazquez, E., Villaverde, A. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2013)
Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces.
Nanomedicine, 9(2),
pp. 207-220.
(doi: 10.2217/nnm.13.43)
(PMID:23631503)
Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, McMurray, R.J., Burgess, K.V., Alakpa, E.V., Reynolds, Paul
ORCID: https://orcid.org/0000-0001-7614-0008, Murawski, K., Kingham, E., Oreffo, R.O.C., Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2012)
Using nanotopography and metabolomics to identify biochemical effectors of multipotency.
ACS Nano, 6(11),
pp. 10239-10249.
(doi: 10.1021/nn304046m)
Dalby, M.J. ORCID: https://orcid.org/0000-0002-0528-3359, Macintyre, A., Roberts, J.N.
ORCID: https://orcid.org/0000-0002-8926-1041, Yang, J., Lee, L.C.Y., Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458 and McNamara, L.E.
(2012)
Nanosubstrates to illustrate differential adhesion mechanisms to fibronectin and vitronectin.
Nanomedicine, 7(1),
pp. 17-21.
(doi: 10.2217/nnm.11.172)
Dalby, M.J. ORCID: https://orcid.org/0000-0002-0528-3359, Macintyre, A., Roberts, J.N., Yang, J., Lee, L..L.C.Y., Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458 and McNamara, L.E.
(2012)
3D patterned agarose hydrogels for investigation of precursor cells in differentiation and chemoattraction.
Nanomedicine, 7(1),
pp. 17-21.
(doi: 10.2217/nnm.11.172)
Dalby, M.J. ORCID: https://orcid.org/0000-0002-0528-3359, Macintyre, A., Roberts, J.N., Yang, J., Lee, L.C.Y., Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458 and McNamara, L.E.
(2012)
Nanoporous titanium substrates for osteogenesis.
Nanomedicine, 7(1),
pp. 17-21.
(doi: 10.2217/nnm.11.172)
Dalby, M.J. ORCID: https://orcid.org/0000-0002-0528-3359, Macintyre, A., Roberts, J.N., Yang, J., Lee, L.C.Y., Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458 and McNamara, L.E.
(2012)
Research Highlights.
Nanomedicine, 7(1),
pp. 17-21.
(doi: 10.2217/nnm.11.172)
McMurray, R.J., Gadegaard, N. ORCID: https://orcid.org/0000-0002-3396-846X, Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458, Burgess, K.V., McNamara, L.E., Tare, R., Murawski, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2011)
Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency.
Nature Materials, 10(8),
pp. 637-644.
(doi: 10.1038/nmat3058)
(PMID:21765399)
Kingham, E.J., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X, Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Oreffo, R.O.C.
(2011)
Nanotopography induced osteogenic differentiation of human stem cells.
Bone, 48(Sup. 2),
S108-S109.
(doi: 10.1016/j.bone.2011.03.177)
Hannigan, A., Qureshi, A.M., Nixon, C., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Jones, S., Philbey, A.W. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2011)
Lymphocyte deficiency limits Epstein-Barr virus latent membrane protein 1 induced chronic inflammation and carcinogenic pathology in vivo.
Molecular Cancer, 10(11),
pp. 1-20.
(doi: 10.1186/1476-4598-10-11)
McNamara, L.E., McMurray, R.J., Dalby, M.J. ORCID: https://orcid.org/0000-0002-0528-3359 and Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458
(2011)
Surfaces and Cell Behavior.
Comprehensive Biomaterials, 4(409),
pp. 115-126.
(doi: 10.1016/B978-0-08-055294-1.00010-6)
Nokhbatolfoghahai, M., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Wilson, J.B. and Downie, J.R.
(2011)
Evolutionary analysis of genes involved in cement gland development in anurans.
Iranian Journal of Science and Technology, A3,
Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X, Burgess, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2011)
Mechanotransduction and skeletal stem cell differentiation in response to bioactive nanotopography.
Histology and Histopathology: Cellular and Molecular Biology, 26(S1),
31.012.
Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X, Oreffo, R.O.C. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2011)
Effects of nanotopography on cell adhesion, morphology and differentiation.
European Cells and Materials, 22(S2),
p. 14.
McMurray, R.J., Gadegaard, N. ORCID: https://orcid.org/0000-0002-3396-846X, Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359, Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458, Maclaine, S., Meek, D., McNamara, L.E., Child, H. and Berry, C.C.
ORCID: https://orcid.org/0000-0002-6485-2187
(2010)
Research highlights.
Nanomedicine, 5(10),
pp. 1495-1499.
(doi: 10.2217/nnm.10.119)
Repellin, C.E, Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Philbey, A.W. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2010)
Lymphoid hyperplasia and lymphoma in transgenic mice expressing the small non-coding RNA, EBER1 of Epstein-Barr virus.
PLoS ONE, 5(2),
e9092.
(doi: 10.1371/journal.pone.0009092)
(PMID:20161707)
(PMCID:PMC2817001)
Rossi, L., Riehle, M.O. ORCID: https://orcid.org/0000-0001-7988-1514, McNamara, L.E., Burchmore, R.
ORCID: https://orcid.org/0000-0003-1663-9004, Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359, McMurray, R.J., Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X, Ahmed, S. and Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458
(2009)
Research highlights.
Nanomedicine, 4(6),
pp. 613-617.
(doi: 10.2217/nnm.09.46)
Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Al-Sheikh, Y., Drotar, M. E., Cushley, W. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2008)
Epstein-Barr virus nuclear antigen-1 renders lymphocytes responsive to IL-2 but not IL-15 for survival.
Journal of General Virology, 89(11),
pp. 2821-2832.
(doi: 10.1099/vir.0.83296-0)
Charalambous, C.T., Hannigan, A., Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, McPhee, G.M. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2007)
Latent membrane protein 1-induced EGFR signalling is negatively regulated by TGF prior to neoplasia.
Carcinogenesis, 28(8),
pp. 1839-1848.
(doi: 10.1093/carcin/bgm055)
Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458 and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2005)
A viral oncogene which induces B-cells to survive in response to IL-2.
Experimental Hematology, 33(S7),
p. 112.
(doi: 10.1016/j.exphem.2005.05.017)
Drotar, M.E., Silva, S., Barone, E., Campbell, D., Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Jurvansu, J., Bhatia, P., Klein, G. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2003)
Epstein-Barr virus nuclear antigen-1 and Myc cooperate in lymphomagenesis.
International Journal of Cancer, 106,
pp. 388-395.
(doi: 10.1002/ijc.11224)
(PMID:12845679)
Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Drotar, M.E., Coy, J.L. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2002)
bcl-x(L) and RAG genes are induced and the response to IL-2 enhanced in E mu EBNA-1 transgenic mouse lymphocytes.
Oncogene, 21,
pp. 5182-5187.
(doi: 10.1038/sj.onc.1205490)
Book Sections
Donnelly, Hannah ORCID: https://orcid.org/0000-0002-5154-9971, Vermeulen, Steven, Tsimbouri, Monica
ORCID: https://orcid.org/0000-0001-5124-7458 and Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2023)
Cell–material interactions.
In: De Boer, Jan and Van Blitterswijk, Clemens A. (eds.)
Tissue Engineering.
Elsevier, pp. 261-292.
ISBN 9780128244593
(doi: 10.1016/B978-0-12-824459-3.00008-1)
Anderson, H., Llopis-Hernandez, V. ORCID: https://orcid.org/0000-0002-7616-7347, Sweeten, P., Donnelly, H., Gurden, R., Orapiriyakul, W., Salmeron-Sanchez, M.
ORCID: https://orcid.org/0000-0002-8112-2100, Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Tsimbouri, M.P.
ORCID: https://orcid.org/0000-0001-5124-7458
(2017)
Nanoscale surface cues and cell behaviour.
In: Hashmi, Saleem (ed.)
Reference Module in Materials Science and Materials Engineering.
Elsevier.
ISBN 9780128035818
(doi: 10.1016/B978-0-12-803581-8.10226-7)
Tsimbouri, Penelope M. ORCID: https://orcid.org/0000-0001-5124-7458, McNamara, Laura E., Alakpa, Enateri V., Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Turner, Lesley-Anne
(2015)
Cell material interactions.
In: van Blitterswijk, Clemens A. and de Boer, Jan (eds.)
Tissue Engineering.
Elsevier, pp. 217-251.
ISBN 9780124202108
(doi: 10.1016/B978-0-12-420145-3.00007-9)
Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, O'Donnell, M.A. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2001)
Selection and enrichment of B cells from lymphoid tissues.
In: Wilson, J.B,. and May, G.H.W. (eds.)
Epstein-Barr Virus Protocols.
Series: Methods in Molecular Biology (174).
The Humana Press Inc.: Totowa, N.J., pp. 411-421.
ISBN 9780896036901
(doi: 10.1385/1-59259-227-9:411)
Conference or Workshop Item
Cuahtecontzi Delint, Rosalia, Ishak, I., Tsimbouri, Monica P. ORCID: https://orcid.org/0000-0001-5124-7458, Jayawarna, Vineetha, Nobbs, A., Salmeron-Sanchez, Manuel
ORCID: https://orcid.org/0000-0002-8112-2100, Dalby, Matthew J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Su, B.
(2023)
In-Vitro Studies of 2D Orthopaedic Implants with Cell Instructive Nanotopographies.
TERMIS 2023 – European Chapter, Manchester, UK, 28–31 March 2023.
(doi: 10.1089/ten.tea.2023.29043.abstract)
Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Holloway, N., Fisher, L., Sjostrom, T., Nobbs, A.H., Meek, R.M.D., Su, B. and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2016)
Osteogenic and Bactericidal Surfaces from Hydrothermal Titania Nanowires on Titanium Substrates.
The British Orthopaedic Research Society (BORS) Annual Conference, Glasgow, UK, 5-6 Sept 2016.
McLean, Adele, Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458 and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2008)
Massive Overexpression of Chitnase3-like 4 (YM2), CD30 and Immunoglobulin in LMP1 Induced Inflammation Associated Carcinogenesis.
13th International EBV Symposium, Guangzgou, China, 7-10 Nov 2008.
Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458, Chiou, Yih-Chy and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2008)
EBERs the Small Viral Non-coding RNAs are Tumourigenic and Disturb the Interferon Response in Vivo.
Beatson International Cancer Conference Cell Growth and Metabolism, Glasgow, UK, 15-18 Jun 2008.
Chiou, Yih-Chy, Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458 and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2007)
EBER1 – a Small Viral Non-coding RNA is Tumourigenic and Disturbs the Interferon Response in Vivo.
Beatson International Cancer Conference, Glasgow, UK, 16-20 Jun 2007.
Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458, Al-Sheikh, Yazeed, Mclean, Adele, Drotar, Mark and Wilson, Joanna B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2006)
An Evaluation of the Contribution of EBNA1 Expression to Transgenic Mouse Lymphomagenesis.
12th International EBV Symposium, Boston, MA, USA, 08-12 Jul 2006.
Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458, Drotar, Mark, Hill, E. and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2004)
EBNA1 Induces B-cells to Respond to IL-2 Survival Signals.
11th International EBV Symposium, Regensberg, Germany, 20-25 Sep 2004.
Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458 and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2002)
The Action of EBNA1 as an Oncogene in Vivo.
10th International Symposium on Epstein-Barr Virus and Associated Malignant Diseases, Cairns, Australia, 16-21 Jul 2002.
Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458, Cushley, William and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2000)
EBNA1 Mechanism of Action as an Oncogene.
9th Biennial Conference of the International Assoication for Research on Epstein-Barr Virus, New Haven, CT, USA, 22-27 Jun 2000.
Tsimbouri, Penelope ORCID: https://orcid.org/0000-0001-5124-7458, Cushley, William and Wilson, J.B.
ORCID: https://orcid.org/0000-0003-4715-2530
(2000)
EBNA-1 Action as an Oncogene.
10th TENOVUS Scotland Symposium: Gene Expression and Disease, Glasgow, UK, 10-12 Apr 2000.
Conference Proceedings
Young, P.S., Greer, A.I.M. ORCID: https://orcid.org/0000-0003-2817-5884, Tsimbouri, P.M.
ORCID: https://orcid.org/0000-0001-5124-7458, Meek, R.M.D., Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X and Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359
(2016)
Precision-Engineered Nanotopographical Surfaces to Control Osteoclast Differentiation.
In: The British Orthopaedic Research Society (BORS) Annual Conference, Glasgow, UK, 5-6 Sept 2016,
Adekanmbi, Isaiah, Ferguson, Louisa, Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Riehle, Mathis
ORCID: https://orcid.org/0000-0001-7988-1514, Kubba, Haytham and Tanner, K.E.
ORCID: https://orcid.org/0000-0003-2257-0218
(2016)
Evaluation of Cell Viability of Biodegradable AZ31 Mg Alloy for Use in Paediatric Tracheal Stent after Long Term In Vitro Corrosion.
In: 10th World Biomaterials Congress, Montreal, Canada, 17-22 May 2016,
(doi: 10.3389/conf.FBIOE.2016.01.02513)
Silverwood, R.K., Fairhurst, P., Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Sjostrom, T., Young, P., Su, B., Meek, R.M.D. and Dalby, M.
ORCID: https://orcid.org/0000-0002-0528-3359
(2014)
Analysis of Osteoclastogenesis/Osteoblastogenesis Using Human Bone Marrow Derived Co-Cultures on Nanotopographical Titania Surfaces.
In: Glasgow Meeting of Orthopaedic Research (GLAMOR), Glasgow, UK, 28 Mar 2014,
Herd, J.M., Joseph, J., McGarvey, M., Tsimbouri, P. ORCID: https://orcid.org/0000-0001-5124-7458, Bennett, A., Meek, R.M.D. and Morrison, A.
(2013)
Intra-Operative Cell Salvage in Revision Hip Surgery.
In: Glasgow Meeting of Orthopaedic Research (GLAMOR), Glasgow, 2013,
Khokhar, A.Z., Tsimbouri, P.M. ORCID: https://orcid.org/0000-0001-5124-7458, Dalby, M.J.
ORCID: https://orcid.org/0000-0002-0528-3359 and Gadegaard, N.
ORCID: https://orcid.org/0000-0002-3396-846X
(2011)
Development of ultra-hard stamps for titanium patterning.
In: 37th International Conference on Micro and Nano Engineering: MNE 2011, Berlin, 19 - 23 September 2011,
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Development of NanoKick Bioreactor
Biotechnology and Biological Sciences Research Council
2016 - 2017
- Using nanokicking to discover and exploit differences in mechanical response between normal and cancerous cells
Bone Cancer Research Trust
2015 - 2015
- Manipulation of primary cancer cells by nanotopography
Tenovus Scotland
2013 - 2013
- Manipulation of cancer cells by nanotopography: strategies to control migration, proliferation and apoptosis (ISSF Catalyst Fund)
Wellcome Trust
2011 - 2014
Supervision
- Das, Udipt Ranjan
Nanovibrational stimulation for mesenchymal stromal cell osteogenesis : investigating the relationship between osteogenesis and inflammation'' - Kalli, Paris Alexandros
Beating mesenchymal stem cell senescence with materials that organise growth factors