Dr Beatriz Castejon Vega
- Research Associate (Molecular Biosciences)
https://orcid.org/0000-0003-0286-2395Publications
2023
Castejon-Vega, B. , Cordero, M. D. and Sanz, A. (2023) How the disruption of mitochondrial redox signalling contributes to ageing. Antioxidants, 12(4), 831. (doi: 10.3390/antiox12040831) (PMID:37107206) (PMCID:PMC10135186)
2021
Castejón-Vega, B. et al. (2021) L-arginine ameliorates defective autophagy in GM2 gangliosidoses by mTOR modulation. Cells, 10(11), 3122. (doi: 10.3390/cells10113122)
González‐Dominguez, A., Montañez, R., Castejón‐Vega, B. , Nuñez‐Vasco, J., Lendines‐Cordero, D., Wang, C., Mbalaviele, G., Navarro‐Pando, J. M., Alcocer‐Gómez, E. and Cordero, M. D. (2021) Inhibition of the NLRP3 inflammasome improves lifespan in animal murine model of Hutchinson–Gilford progeria. EMBO Molecular Medicine, 13(10), e14012. (doi: 10.15252/emmm.202114012) (PMID:34448355) (PMCID:PMC8495449)
Navarro-Pando, J. M. et al. (2021) Inhibition of the NLRP3 inflammasome prevents ovarian aging. Science Advances, 7(1), eabc7409. (doi: 10.1126/sciadv.abc7409) (PMID:33523841) (PMCID:PMC7775749)
Castejón-Vega, B. , Battino, M., Quiles, J. L., Bullon, B., Cordero, M. D. and Bullón, P. (2021) Potential role of the mitochondria for the dermatological treatment of Papillon-Lefèvre. Antioxidants, 10(1), 95. (doi: 10.3390/antiox10010095) (PMID:33445524) (PMCID:PMC7827181)
2020
Nicolás-Ávila, J. A. et al. (2020) A network of macrophages supports mitochondrial homeostasis in the heart. Cell, 183(1), 94-109.e23. (doi: 10.1016/j.cell.2020.08.031) (PMID:32937105)
Gallego, P., Castejón-Vega, B. , del Campo, J. A. and Cordero, M. D. (2020) The absence of NLRP3-inflammasome modulates hepatic fibrosis progression, lipid metabolism, and inflammation in KO NLRP3 mice during aging. Cells, 9(10), 2148. (doi: 10.3390/cells9102148) (PMID:32977490) (PMCID:PMC7598267)
Rodríguez-Hernández, M. A. et al. (2020) Integrated molecular signaling involving mitochondrial dysfunction and alteration of cell metabolism induced by tyrosine kinase inhibitors in cancer. Redox Biology, 36, 101510. (doi: 10.1016/j.redox.2020.101510) (PMID:32593127) (PMCID:PMC7322178)
Anderson, R. et al. (2020) NLRP3 inflammasome inhibition by MCC950 in aged mice improves health via enhanced autophagy and PPARα activity. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 75(8), pp. 1457-1464. (doi: 10.1093/gerona/glz239) (PMID:31603987)
Cañadas-Lozano, D., Marín-Aguilar, F., Castejón-Vega, B. , Ryffel, B., Navarro-Pando, J. M., Ruiz-Cabello, J., Alcocer-Gómez, E., Bullón, P. and Cordero, M. D. (2020) Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice. GeroScience, 42(2), pp. 715-725. (doi: 10.1007/s11357-019-00151-6) (PMID:31975052) (PMCID:PMC7206474)
Marín‐Aguilar, F. et al. (2020) NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice. Aging Cell, 19(1), e13050. (doi: 10.1111/acel.13050) (PMID:31625260) (PMCID:PMC6974709)
2018
Bullón, P. et al. (2018) Autophagic dysfunction in patients with Papillon-Lefèvre syndrome is restored by recombinant cathepsin C treatment. Journal of Allergy and Clinical Immunology, 142(4), 1131-1143.e7. (doi: 10.1016/j.jaci.2018.01.018) (PMID:29410039)
2016
Villanueva-Paz, M. et al. (2016) Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells. Genes and Cancer, 7(7-8), pp. 260-277. (doi: 10.18632/genesandcancer.114) (PMID:27738496) (PMCID:PMC5059116)
Articles
Castejon-Vega, B. , Cordero, M. D. and Sanz, A. (2023) How the disruption of mitochondrial redox signalling contributes to ageing. Antioxidants, 12(4), 831. (doi: 10.3390/antiox12040831) (PMID:37107206) (PMCID:PMC10135186)
Castejón-Vega, B. et al. (2021) L-arginine ameliorates defective autophagy in GM2 gangliosidoses by mTOR modulation. Cells, 10(11), 3122. (doi: 10.3390/cells10113122)
González‐Dominguez, A., Montañez, R., Castejón‐Vega, B. , Nuñez‐Vasco, J., Lendines‐Cordero, D., Wang, C., Mbalaviele, G., Navarro‐Pando, J. M., Alcocer‐Gómez, E. and Cordero, M. D. (2021) Inhibition of the NLRP3 inflammasome improves lifespan in animal murine model of Hutchinson–Gilford progeria. EMBO Molecular Medicine, 13(10), e14012. (doi: 10.15252/emmm.202114012) (PMID:34448355) (PMCID:PMC8495449)
Navarro-Pando, J. M. et al. (2021) Inhibition of the NLRP3 inflammasome prevents ovarian aging. Science Advances, 7(1), eabc7409. (doi: 10.1126/sciadv.abc7409) (PMID:33523841) (PMCID:PMC7775749)
Castejón-Vega, B. , Battino, M., Quiles, J. L., Bullon, B., Cordero, M. D. and Bullón, P. (2021) Potential role of the mitochondria for the dermatological treatment of Papillon-Lefèvre. Antioxidants, 10(1), 95. (doi: 10.3390/antiox10010095) (PMID:33445524) (PMCID:PMC7827181)
Nicolás-Ávila, J. A. et al. (2020) A network of macrophages supports mitochondrial homeostasis in the heart. Cell, 183(1), 94-109.e23. (doi: 10.1016/j.cell.2020.08.031) (PMID:32937105)
Gallego, P., Castejón-Vega, B. , del Campo, J. A. and Cordero, M. D. (2020) The absence of NLRP3-inflammasome modulates hepatic fibrosis progression, lipid metabolism, and inflammation in KO NLRP3 mice during aging. Cells, 9(10), 2148. (doi: 10.3390/cells9102148) (PMID:32977490) (PMCID:PMC7598267)
Rodríguez-Hernández, M. A. et al. (2020) Integrated molecular signaling involving mitochondrial dysfunction and alteration of cell metabolism induced by tyrosine kinase inhibitors in cancer. Redox Biology, 36, 101510. (doi: 10.1016/j.redox.2020.101510) (PMID:32593127) (PMCID:PMC7322178)
Anderson, R. et al. (2020) NLRP3 inflammasome inhibition by MCC950 in aged mice improves health via enhanced autophagy and PPARα activity. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 75(8), pp. 1457-1464. (doi: 10.1093/gerona/glz239) (PMID:31603987)
Cañadas-Lozano, D., Marín-Aguilar, F., Castejón-Vega, B. , Ryffel, B., Navarro-Pando, J. M., Ruiz-Cabello, J., Alcocer-Gómez, E., Bullón, P. and Cordero, M. D. (2020) Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice. GeroScience, 42(2), pp. 715-725. (doi: 10.1007/s11357-019-00151-6) (PMID:31975052) (PMCID:PMC7206474)
Marín‐Aguilar, F. et al. (2020) NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice. Aging Cell, 19(1), e13050. (doi: 10.1111/acel.13050) (PMID:31625260) (PMCID:PMC6974709)
Bullón, P. et al. (2018) Autophagic dysfunction in patients with Papillon-Lefèvre syndrome is restored by recombinant cathepsin C treatment. Journal of Allergy and Clinical Immunology, 142(4), 1131-1143.e7. (doi: 10.1016/j.jaci.2018.01.018) (PMID:29410039)
Villanueva-Paz, M. et al. (2016) Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells. Genes and Cancer, 7(7-8), pp. 260-277. (doi: 10.18632/genesandcancer.114) (PMID:27738496) (PMCID:PMC5059116)