2025

Kimpton, Louise M., Paun, L. Mihaela, Colebank, Mitchel J. and Volodina, Victoria (2025) Challenges and opportunities in uncertainty quantification for healthcare and biological systems. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 383(2292), 20240232. (doi: 10.1098/rsta.2024.0232) (PMID:40078151) (PMCID:PMC11904623)

Paun, L. Mihaela, Colebank, Mitchel J. and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2025) A comparison of Gaussian processes and polynomial chaos emulators in the context of haemodynamic pulse-wave propagation modelling. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 383(2292), 20240222. (doi: 10.1098/rsta.2024.0222) (PMID:40078149) (PMCID:PMC11904621)

Taylor-LaPole, Alyssa M., Paun, L. Mihaela, Lior, Dan, Weigand, Justin D., Puelz, Charles and Olufsen, Mette S. (2025) Parameter selection and optimization of a computational network model of blood flow in single-ventricle patients. Journal of the Royal Society: Interface, 22(223), 20240663. (doi: 10.1098/rsif.2024.0663) (PMID:40013336) (PMCID:PMC11865955)

2024

Paun, L. M. et al. (2024) SECRET: Statistical Emulation for Computational Reverse Engineering and Translation with applications in healthcare. Computer Methods in Applied Mechanics and Engineering, 430, 117193. (doi: 10.1016/j.cma.2024.117193)

Paun, Mihaela, Fensterseifer Schmidt, André, Mcginty, Sean ORCID: https://orcid.org/0000-0002-2428-2669 and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2024) Constrained Bayesian optimization with a cardiovascular application. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 480(2295), 20230371. (doi: 10.1098/rspa.2023.0371)

2022

Paun, L. Mihaela, Schmidt, André Fensterseifer, Mcginty, Sean ORCID: https://orcid.org/0000-0002-2428-2669 and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2022) Statistical Inference for Optimisation of Drug Delivery from Stents. In: Proceedings of the 4th International Conference on Statistics: Theory and Applications (ICSTA 22), Prague, Czech Republic, 28-30 July 2022, ISBN 9781990800085 (doi: 10.11159/icsta22.138)

Paun, L. Mihaela and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2022) Emulation-accelerated Hamiltonian Monte Carlo algorithms for parameter estimation and uncertainty quantification in differential equation models. Statistics and Computing, 32(1), 1. (doi: 10.1007/s11222-021-10060-4)

2021

Paun, L. Mihaela, Borowska, Agnieszka ORCID: https://orcid.org/0000-0001-9123-6227, Colebank, Mitchel J., Olufsen, Mette S. and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2021) Inference in Cardiovascular Modelling Subject to Medical Interventions. In: 3rd International Conference on Statistics: Theory and Applications (ICSTA'21), 29-31 Jul 2021, p. 109. ISBN 9781927877913 (doi: 10.11159/icsta21.109)

Paun, L. Mihaela and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2021) Markov chain Monte Carlo with Gaussian processes for fast parameter estimation and uncertainty quantification in a 1D fluid‐dynamics model of the pulmonary circulation. International Journal for Numerical Methods in Biomedical Engineering, 37(2), e3421. (doi: 10.1002/cnm.3421) (PMID:33249755) (PMCID:PMC7901000)

2020

Paun, L. Mihaela, Colebank, Mitchel J., Olufsen, Mette S., Hill, Nicholas A. ORCID: https://orcid.org/0000-0003-3079-828X and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2020) Assessing model mismatch and model selection in a Bayesian uncertainty quantification analysis of a fluid-dynamics model of pulmonary blood circulation. Journal of the Royal Society: Interface, 17(173), 20200886. (doi: 10.1098/rsif.2020.0886) (PMID:33353505)

Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 and Paun, L. Mihaela (2020) Closed-loop effects in cardiovascular clinical decision support. In: Ladde, Gangaram and Samia, Noelle (eds.) Proceedings of the 2nd International Conference on Statistics: Theory and Applications (ICSTA'20). Avestia Publishing: Ottawa, Canada, p. 128. ISBN 9781927877685 (doi: 10.11159/icsta20.128)

Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 and Paun, L. Mihaela (2020) Closed-loop effects in coupling cardiac physiological models to clinical interventions. In: Irigoien, Itziar, Lee, Dae-Jin, Martínez-Minaya, Joaquín and Rodríguez-Álvarez, María Xosé (eds.) Proceedings of the 35th International Workshop on Statistical Modelling. Servicio Editorial de la Universidad del País Vasco: Bilbao, Spain, pp. 120-125. ISBN 9788413192673

2019

Colebank, Mitchell J., Paun, L. Mihaela, Qureshi, M. Umar, Chesler, Naomi, Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413, Olufsen, Mette S. and Ellwein Fix, Laura (2019) Influence of image segmentation on one-dimensional fluid dynamics predictions in the mouse pulmonary arteries. Journal of the Royal Society: Interface, 16, 20190284. (doi: 10.1098/rsif.2019.0284)

Umar Qureshi, M., Colebank, Mitchel J., Paun, Luiza Mihaela, Ellwein, Laura, Chesler, Naomi, Haider, Mansoor A., Hill, Nicholas A. ORCID: https://orcid.org/0000-0003-3079-828X, Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 and Olufsen, Mette S. (2019) Hemodynamic assessment of pulmonary hypertension in mice: a model based analysis of the disease mechanism. Biomechanics and Modeling in Mechanobiology, 18(1), pp. 219-243. (doi: 10.1007/s10237-018-1078-8) (PMID:30284059)

2018

Păun, L. Mihaela, Qureshi, M. Umar, Colebank, Mitchel, Hill, Nicholas A. ORCID: https://orcid.org/0000-0003-3079-828X, Olufsen, Mette S., Haider, Mansoor A. and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2018) MCMC methods for inference in a mathematical model of pulmonary circulation. Statistica Neerlandica, 72(3), pp. 306-338. (doi: 10.1111/stan.12132)

Articles

Kimpton, Louise M., Paun, L. Mihaela, Colebank, Mitchel J. and Volodina, Victoria (2025) Challenges and opportunities in uncertainty quantification for healthcare and biological systems. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 383(2292), 20240232. (doi: 10.1098/rsta.2024.0232) (PMID:40078151) (PMCID:PMC11904623)

Paun, L. Mihaela, Colebank, Mitchel J. and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2025) A comparison of Gaussian processes and polynomial chaos emulators in the context of haemodynamic pulse-wave propagation modelling. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 383(2292), 20240222. (doi: 10.1098/rsta.2024.0222) (PMID:40078149) (PMCID:PMC11904621)

Taylor-LaPole, Alyssa M., Paun, L. Mihaela, Lior, Dan, Weigand, Justin D., Puelz, Charles and Olufsen, Mette S. (2025) Parameter selection and optimization of a computational network model of blood flow in single-ventricle patients. Journal of the Royal Society: Interface, 22(223), 20240663. (doi: 10.1098/rsif.2024.0663) (PMID:40013336) (PMCID:PMC11865955)

Paun, L. M. et al. (2024) SECRET: Statistical Emulation for Computational Reverse Engineering and Translation with applications in healthcare. Computer Methods in Applied Mechanics and Engineering, 430, 117193. (doi: 10.1016/j.cma.2024.117193)

Paun, Mihaela, Fensterseifer Schmidt, André, Mcginty, Sean ORCID: https://orcid.org/0000-0002-2428-2669 and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2024) Constrained Bayesian optimization with a cardiovascular application. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 480(2295), 20230371. (doi: 10.1098/rspa.2023.0371)

Paun, L. Mihaela and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2022) Emulation-accelerated Hamiltonian Monte Carlo algorithms for parameter estimation and uncertainty quantification in differential equation models. Statistics and Computing, 32(1), 1. (doi: 10.1007/s11222-021-10060-4)

Paun, L. Mihaela and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2021) Markov chain Monte Carlo with Gaussian processes for fast parameter estimation and uncertainty quantification in a 1D fluid‐dynamics model of the pulmonary circulation. International Journal for Numerical Methods in Biomedical Engineering, 37(2), e3421. (doi: 10.1002/cnm.3421) (PMID:33249755) (PMCID:PMC7901000)

Paun, L. Mihaela, Colebank, Mitchel J., Olufsen, Mette S., Hill, Nicholas A. ORCID: https://orcid.org/0000-0003-3079-828X and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2020) Assessing model mismatch and model selection in a Bayesian uncertainty quantification analysis of a fluid-dynamics model of pulmonary blood circulation. Journal of the Royal Society: Interface, 17(173), 20200886. (doi: 10.1098/rsif.2020.0886) (PMID:33353505)

Colebank, Mitchell J., Paun, L. Mihaela, Qureshi, M. Umar, Chesler, Naomi, Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413, Olufsen, Mette S. and Ellwein Fix, Laura (2019) Influence of image segmentation on one-dimensional fluid dynamics predictions in the mouse pulmonary arteries. Journal of the Royal Society: Interface, 16, 20190284. (doi: 10.1098/rsif.2019.0284)

Umar Qureshi, M., Colebank, Mitchel J., Paun, Luiza Mihaela, Ellwein, Laura, Chesler, Naomi, Haider, Mansoor A., Hill, Nicholas A. ORCID: https://orcid.org/0000-0003-3079-828X, Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 and Olufsen, Mette S. (2019) Hemodynamic assessment of pulmonary hypertension in mice: a model based analysis of the disease mechanism. Biomechanics and Modeling in Mechanobiology, 18(1), pp. 219-243. (doi: 10.1007/s10237-018-1078-8) (PMID:30284059)

Păun, L. Mihaela, Qureshi, M. Umar, Colebank, Mitchel, Hill, Nicholas A. ORCID: https://orcid.org/0000-0003-3079-828X, Olufsen, Mette S., Haider, Mansoor A. and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2018) MCMC methods for inference in a mathematical model of pulmonary circulation. Statistica Neerlandica, 72(3), pp. 306-338. (doi: 10.1111/stan.12132)

Book Sections

Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 and Paun, L. Mihaela (2020) Closed-loop effects in cardiovascular clinical decision support. In: Ladde, Gangaram and Samia, Noelle (eds.) Proceedings of the 2nd International Conference on Statistics: Theory and Applications (ICSTA'20). Avestia Publishing: Ottawa, Canada, p. 128. ISBN 9781927877685 (doi: 10.11159/icsta20.128)

Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 and Paun, L. Mihaela (2020) Closed-loop effects in coupling cardiac physiological models to clinical interventions. In: Irigoien, Itziar, Lee, Dae-Jin, Martínez-Minaya, Joaquín and Rodríguez-Álvarez, María Xosé (eds.) Proceedings of the 35th International Workshop on Statistical Modelling. Servicio Editorial de la Universidad del País Vasco: Bilbao, Spain, pp. 120-125. ISBN 9788413192673

Conference Proceedings

Paun, L. Mihaela, Schmidt, André Fensterseifer, Mcginty, Sean ORCID: https://orcid.org/0000-0002-2428-2669 and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2022) Statistical Inference for Optimisation of Drug Delivery from Stents. In: Proceedings of the 4th International Conference on Statistics: Theory and Applications (ICSTA 22), Prague, Czech Republic, 28-30 July 2022, ISBN 9781990800085 (doi: 10.11159/icsta22.138)

Paun, L. Mihaela, Borowska, Agnieszka ORCID: https://orcid.org/0000-0001-9123-6227, Colebank, Mitchel J., Olufsen, Mette S. and Husmeier, Dirk ORCID: https://orcid.org/0000-0003-1673-7413 (2021) Inference in Cardiovascular Modelling Subject to Medical Interventions. In: 3rd International Conference on Statistics: Theory and Applications (ICSTA'21), 29-31 Jul 2021, p. 109. ISBN 9781927877913 (doi: 10.11159/icsta21.109)