2021

Connolly, J. P.R., Turner, N. C.A., Hallam, J., Rimbi, P. T., Flett, T., McCormack, M. J., Roe, A. J. and O'Boyle, N. (2021) D-serine induces distinct transcriptomes in diverse Escherichia coli pathotypes. Microbiology, 167(10), 001093. (doi: 10.1099/mic.0.001093) (PMID:34623236)

O'Boyle, N. and Roe, A. J. (2021) Heterogeneity in populations of enterohaemorrhagic Escherichia coli undergoing D-serine adaptation. Current Genetics, 67(2), pp. 221-224. (doi: 10.1007/s00294-020-01130-7) (PMID:33219834)

Mordue, J., O'Boyle, N., Gadegaard, N. and Roe, A. J. (2021) The force awakens: the dark side of mechanosensing in bacterial pathogens. Cellular Signalling, 78, 109867. (doi: 10.1016/j.cellsig.2020.109867) (PMID:33279672)

Connolly, J. P.R., Roe, A. J. and O'Boyle, N. (2021) Prokaryotic life finds a way: insights from evolutionary experimentation in bacteria. Critical Reviews in Microbiology, 47(1), pp. 126-140. (doi: 10.1080/1040841X.2020.1854172) (PMID:33332206)

2020

O'Boyle, N., Berry, C. C. and Davies, R. L. (2020) Differentiated ovine tracheal epithelial cells support the colonisation of pathogenic and non-pathogenic strains of Mannheimia haemolytica. Scientific Reports, 10, 14971. (doi: 10.1038/s41598-020-71604-8) (PMID:32917945) (PMCID:PMC7486916)

O'Boyle, N., Connolly, J. P.R., Tucker, N. P. and Roe, A. J. (2020) Genomic plasticity of pathogenic Escherichia coli mediates D-serine tolerance via multiple adaptive mechanisms. Proceedings of the National Academy of Sciences of the United States of America, 117(36), pp. 22484-22493. (doi: 10.1073/pnas.2004977117) (PMID:32848072) (PMCID:PMC7486766)

Connolly, J. P.R., O'Boyle, N. and Roe, A. J. (2020) Widespread strain-specific distinctions in chromosomal binding dynamics of a highly conserved Escherichia coli transcription factor. mBio, 11, e01058-20. (doi: 10.1128/mBio.01058-20) (PMID:32576674) (PMCID:PMC7315121)

O'Boyle, N., Turner, N. C.A., Roe, A. J. and Connolly, J. P.R. (2020) Plastic circuits: regulatory flexibility in fine tuning pathogen success. Trends in Microbiology, 28(5), pp. 360-371. (doi: 10.1016/j.tim.2020.01.002) (PMID:32298614)

Fox, S., Goswami, C. , Holden, M., Connolly, J. P.R., Mordue, J., O'Boyle, N., Roe, A. , Connor, M., Leanord, A. and Evans, T. J. (2020) A highly conserved complete accessory Escherichia coli type III secretion system 2 is widespread in bloodstream isolates of the ST69 lineage. Scientific Reports, 10, 4135. (doi: 10.1038/s41598-020-61026-x) (PMID:32139768) (PMCID:PMC7058095)

2019

Connolly, J. P.R., O'Boyle, N., Turner, N., Browning, D. F. and Roe, A. J. (2019) Distinct intra-species virulence mechanisms regulated by a conserved transcription factor. Proceedings of the National Academy of Sciences of the United States of America, 116(39), pp. 19695-19704. (doi: 10.1073/pnas.1903461116) (PMID:31501343) (PMCID:PMC6765310)

McHugh, R. E., O'Boyle, N., Connolly, J. P.R., Hoskisson, P. A. and Roe, A. J. (2019) Characterisation of the mode of action of Aurodox, a Type III secretion system inhibitor from Streptomyces goldiniensis. Infection and Immunity, 87(2), e00595-18. (doi: 10.1128/IAI.00595-18) (PMID:30455200) (PMCID:PMC6346137)

2018

O'Boyle, N., Sutherland, E., Berry, C. C. and Davies, R. L. (2018) Optimisation of growth conditions for ovine airway epithelial cell differentiation at an air-liquid interface. PLoS ONE, 13(3), e0193998. (doi: 10.1371/journal.pone.0193998) (PMID:29518140) (PMCID:PMC5843276)

O'Boyle, N., Connolly, J. P.R. and Roe, A. J. (2018) Tracking elusive cargo: Illuminating spatio-temporal type 3 effector protein dynamics using reporters. Cellular Microbiology, 20(1), e12797. (doi: 10.1111/cmi.12797) (PMID:29087624) (PMCID:PMC5765406)

Connolly, J. P.R. et al. (2018) Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion. Nature Communications, 9, 4187. (doi: 10.1038/s41467-018-06701-4) (PMID:30305622) (PMCID:PMC6180029)

2017

O'Boyle, N., Sutherland, E., Berry, C. C. and Davies, R. L. (2017) Temporal dynamics of ovine airway epithelial cell differentiation at an air-liquid interface. PLoS ONE, 12(7), e0181583. (doi: 10.1371/journal.pone.0181583) (PMID:28746416) (PMCID:PMC5529025)

Articles

Connolly, J. P.R., Turner, N. C.A., Hallam, J., Rimbi, P. T., Flett, T., McCormack, M. J., Roe, A. J. and O'Boyle, N. (2021) D-serine induces distinct transcriptomes in diverse Escherichia coli pathotypes. Microbiology, 167(10), 001093. (doi: 10.1099/mic.0.001093) (PMID:34623236)

O'Boyle, N. and Roe, A. J. (2021) Heterogeneity in populations of enterohaemorrhagic Escherichia coli undergoing D-serine adaptation. Current Genetics, 67(2), pp. 221-224. (doi: 10.1007/s00294-020-01130-7) (PMID:33219834)

Mordue, J., O'Boyle, N., Gadegaard, N. and Roe, A. J. (2021) The force awakens: the dark side of mechanosensing in bacterial pathogens. Cellular Signalling, 78, 109867. (doi: 10.1016/j.cellsig.2020.109867) (PMID:33279672)

Connolly, J. P.R., Roe, A. J. and O'Boyle, N. (2021) Prokaryotic life finds a way: insights from evolutionary experimentation in bacteria. Critical Reviews in Microbiology, 47(1), pp. 126-140. (doi: 10.1080/1040841X.2020.1854172) (PMID:33332206)

O'Boyle, N., Berry, C. C. and Davies, R. L. (2020) Differentiated ovine tracheal epithelial cells support the colonisation of pathogenic and non-pathogenic strains of Mannheimia haemolytica. Scientific Reports, 10, 14971. (doi: 10.1038/s41598-020-71604-8) (PMID:32917945) (PMCID:PMC7486916)

O'Boyle, N., Connolly, J. P.R., Tucker, N. P. and Roe, A. J. (2020) Genomic plasticity of pathogenic Escherichia coli mediates D-serine tolerance via multiple adaptive mechanisms. Proceedings of the National Academy of Sciences of the United States of America, 117(36), pp. 22484-22493. (doi: 10.1073/pnas.2004977117) (PMID:32848072) (PMCID:PMC7486766)

Connolly, J. P.R., O'Boyle, N. and Roe, A. J. (2020) Widespread strain-specific distinctions in chromosomal binding dynamics of a highly conserved Escherichia coli transcription factor. mBio, 11, e01058-20. (doi: 10.1128/mBio.01058-20) (PMID:32576674) (PMCID:PMC7315121)

O'Boyle, N., Turner, N. C.A., Roe, A. J. and Connolly, J. P.R. (2020) Plastic circuits: regulatory flexibility in fine tuning pathogen success. Trends in Microbiology, 28(5), pp. 360-371. (doi: 10.1016/j.tim.2020.01.002) (PMID:32298614)

Fox, S., Goswami, C. , Holden, M., Connolly, J. P.R., Mordue, J., O'Boyle, N., Roe, A. , Connor, M., Leanord, A. and Evans, T. J. (2020) A highly conserved complete accessory Escherichia coli type III secretion system 2 is widespread in bloodstream isolates of the ST69 lineage. Scientific Reports, 10, 4135. (doi: 10.1038/s41598-020-61026-x) (PMID:32139768) (PMCID:PMC7058095)

Connolly, J. P.R., O'Boyle, N., Turner, N., Browning, D. F. and Roe, A. J. (2019) Distinct intra-species virulence mechanisms regulated by a conserved transcription factor. Proceedings of the National Academy of Sciences of the United States of America, 116(39), pp. 19695-19704. (doi: 10.1073/pnas.1903461116) (PMID:31501343) (PMCID:PMC6765310)

McHugh, R. E., O'Boyle, N., Connolly, J. P.R., Hoskisson, P. A. and Roe, A. J. (2019) Characterisation of the mode of action of Aurodox, a Type III secretion system inhibitor from Streptomyces goldiniensis. Infection and Immunity, 87(2), e00595-18. (doi: 10.1128/IAI.00595-18) (PMID:30455200) (PMCID:PMC6346137)

O'Boyle, N., Sutherland, E., Berry, C. C. and Davies, R. L. (2018) Optimisation of growth conditions for ovine airway epithelial cell differentiation at an air-liquid interface. PLoS ONE, 13(3), e0193998. (doi: 10.1371/journal.pone.0193998) (PMID:29518140) (PMCID:PMC5843276)

O'Boyle, N., Connolly, J. P.R. and Roe, A. J. (2018) Tracking elusive cargo: Illuminating spatio-temporal type 3 effector protein dynamics using reporters. Cellular Microbiology, 20(1), e12797. (doi: 10.1111/cmi.12797) (PMID:29087624) (PMCID:PMC5765406)

Connolly, J. P.R. et al. (2018) Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion. Nature Communications, 9, 4187. (doi: 10.1038/s41467-018-06701-4) (PMID:30305622) (PMCID:PMC6180029)

O'Boyle, N., Sutherland, E., Berry, C. C. and Davies, R. L. (2017) Temporal dynamics of ovine airway epithelial cell differentiation at an air-liquid interface. PLoS ONE, 12(7), e0181583. (doi: 10.1371/journal.pone.0181583) (PMID:28746416) (PMCID:PMC5529025)