Professor Alain Kohl

Affiliate (School of Infection & Immunity)

Centre for Virus Research, 464 Bearsden Road, Glasgow, G61 1qh

Research interests

Virus image CVR Supporting COVID-19 Research Response

Arboviruses are transmitted by arthropod vectors such as mosquitoes, midges or ticks to susceptible vertebrates. They can cause disease in humans and animals, displaying a variety of symptoms. Most arboviruses group into four RNA virus families, the Flaviviridae, Bunyaviridae, Togaviridae and Reoviridae.

Dengue virus, Zika virus (both of the Flaviridae family) and chikungunya virus (Togaviridae family) are particularly prominent human pathogens.

Dengue virus alone causes an important number of human infections each year, and chikungunya and Zika viruses has recently emerged in the Americas. Among animal pathogens, the Rift Valley fever virus is of particular interest to us.

We now know that arbovirus replication and dissemination in arthropod vectors leads to activation of a variety of host responses (immune signalling pathways, RNA interference, other responses) which control arboviruses, and this appears to have consequences also for transmission.

Studies on vector immune responses to arbovirus infection as well as viral interference with these response therefore do not just increase our overall understanding of virus/host interactions but may also lead to clues on how to best stop transmission from the arthropod vector.

We have an important number of virus and reporter systems available to study the viruses above as well as model arboviruses such as Semliki Forest virus or Bunymwera virus. Our work on arthropod cells is now being extended to study to live mosquitoes where we are currently establishing a genetic modification programme. We also investigate the effects of endosymbiotic Wolbachia bacteria on arbovirus transmission. A further interest of the group is focused on the host responses of vertebrate cells in response to virus infection, and virus-host interactions.

The CVR is dynamic environment to carry out modern virology work. We have access to state of the art facilities including insectaries at high containment level. Prospective students or post-doctoral fellows are encouraged to apply by email (alain.kohl@glasgow.ac.uk).

Publications

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Jump to: 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2000 | 1999 | 1997

Number of items: 147.

2024

Ribeiro da Silva, S. J. et al. (2024) Development and field validation of an RT-LAMP assay for the rapid detection of chikungunya virus in patient and mosquito samples. Clinical Microbiology and Infection, (doi: 10.1016/j.cmi.2024.03.004) (PMID:38460820) (Early Online Publication)

Tandavanitj, R., Setthapramote, C., De Lorenzo, G. , Sanchez-Velazquez, R., Clark, J. J., Rocchi, M., McInnes, C., Kohl, A. and Patel, A. H. (2024) Virus-like particles of louping ill virus elicit potent neutralizing antibodies targeting multimers of viral envelope protein. Vaccine, (doi: 10.1016/j.vaccine.2024.03.008) (In Press)

Rainey, S. M., Lefteri, D. A. , Darby, C., Kohl, A. , Merits, A. and Sinkins, S. P. (2024) Evidence of differences in cellular regulation of Wolbachia-mediated viral inhibition between alphaviruses and flaviviruses. Viruses, 16(1), 115. (doi: 10.3390/v16010115) (PMID:38257815) (PMCID:PMC10818798)

2023

Gonzalo Nadal, V. et al. (2023) Suspected tick-borne flavivirus meningoencephalomyelitis in dogs from the UK: six cases (2021). Journal of Small Animal Practice, (doi: 10.1111/jsap.13682) (PMID:37956993) (Early Online Publication)

Leggewie, M. et al. (2023) The Aedes aegypti RNA interference response against Zika virus in the context of co-infection with dengue and chikungunya viruses. PLoS Neglected Tropical Diseases, 17(7), e0011456. (doi: 10.1371/journal.pntd.0011456) (PMID:37440582) (PMCID:PMC10343070)

Ribeiro da Silva, S. J., Kohl, A. , Pena, L. and Pardee, K. (2023) Clinical and laboratory diagnosis of monkeypox (mpox): current status and future directions. iScience, 26(6), 106759. (doi: 10.1016/j.isci.2023.106759) (PMID:37206155) (PMCID:PMC10183700)

Laureti, M., Lee, R.-L., Bennett, A., Wilson, L. A., Sy, V. E., Kohl, A. and Dietrich, I. (2023) Rift Valley Fever Virus primes immune responses in Aedes aegypti cells. Pathogens, 12(4), 563. (doi: 10.3390/pathogens12040563) (PMID:37111448) (PMCID:PMC10146816)

Mancini, M. V. et al. (2023) Evaluation of an engineered Zika virus-like particle vaccine candidate in a mosquito-mouse transmission model. mSphere, 8(2), e00564-22. (doi: 10.1128/msphere.00564-22) (PMID:36840596) (PMCID:PMC10117074)

Pondeville, E. et al. (2023) Infravec2 guidelines for the design and operation of containment level 2 and 3 insectaries in Europe. Pathogens and Global Health, 117(3), pp. 293-307. (doi: 10.1080/20477724.2022.2108639) (PMID:35996820) (PMCID:PMC10081053)

Alexander, A. J.T. et al. (2023) Characterisation of the antiviral RNA interference response to Toscana virus in sand fly cells. PLoS Pathogens, 19(3), e1011283. (doi: 10.1371/journal.ppat.1011283) (PMID:36996243) (PMCID:PMC10112792)

Ayers, V. B., Huang, Y.-J. S., Dunlop, J. I., Kohl, A. , Brennan, B. , Higgs, S. and Vanlandingham, D. L. (2023) Immunogenicity of a candidate live attenuated vaccine for Rift Valley fever virus with a two-segmented genome. Viral Immunology, 36(1), pp. 33-40. (doi: 10.1089/vim.2022.0104) (PMID:36399689) (PMCID:PMC9885543)

Ayers, V. B., Huang, Y.-J. S., Kohl, A. , Dunlop, J. I., Hettenbach, S. M., Park, S. L., Higgs, S. and Vanlandingham, D. L. (2023) Comparison of immunogenicity between a candidate live attenuated vaccine and an inactivated vaccine for Cache Valley virus. Viral Immunology, 36(1), pp. 41-47. (doi: 10.1089/vim.2022.0103) (PMID:36622942) (PMCID:PMC9885547)

Ribeiro da Silva, S. J., Kohl, A. , Pena, L. and Pardee, K. (2023) Recent insights into SARS‐CoV‐2 omicron variant. Reviews in Medical Virology, 33(1), e2373. (doi: 10.1002/rmv.2373) (PMID:35662313) (PMCID:PMC9347414)

2022

Ayers, V. B., Huang, Y.-J. S., Dunlop, J. I., Kohl, A. , Brennan, B. , Higgs, S. and Vanlandingham, D. L. (2022) Replication kinetics of a candidate live-attenuated vaccine for Cache Valley virus in Aedes albopictus. Vector-Borne and Zoonotic Diseases, 22(11), pp. 553-558. (doi: 10.1089/vbz.2022.0053) (PMID:36354965) (PMCID:PMC9700352)

da Silva, S. J. R. et al. (2022) Two years into the COVID-19 pandemic: lessons learned. ACS Infectious Diseases, 8(9), pp. 1758-1814. (doi: 10.1021/acsinfecdis.2c00204) (PMID:35940589) (PMCID:PMC9380879)

Bamford, C. G.C., Aranday-Cortes, E. , Sanchez-Velazquez, R., Mullan, C., Kohl, A. , Patel, A. H. , Wilson, S. J. and McLauchlan, J. (2022) A human and rhesus macaque interferon-stimulated gene screen shows that over-expression of ARHGEF3/XPLN inhibits replication of hepatitis C virus and other flavivirids. Viruses, 14(8), 1655. (doi: 10.3390/v14081655) (PMID:36016278) (PMCID:PMC9414520)

Crawford, C. L. et al. (2022) SARM1 depletion slows axon degeneration in a CNS model of neurotropic viral infection. Frontiers in Molecular Neuroscience, 15, 860410. (doi: 10.3389/fnmol.2022.860410) (PMID:35493328) (PMCID:PMC9043327)

Bryden, S. R. et al. (2022) Exploration of immunological responses underpinning severe fever with thrombocytopenia syndrome virus infection reveals IL-6 as a therapeutic target in an immunocompromised mouse model. PNAS Nexus, 1(1), pgac024. (doi: 10.1093/pnasnexus/pgac024) (PMID:35529317) (PMCID:PMC9071185)

da Silva, S. J. R., de Lima, S. C., da Silva, R. C., Kohl, A. and Pena, L. (2022) Viral load in COVID-19 patients: implications for prognosis and vaccine efficacy in the context of emerging SARS-CoV-2 variants. Frontiers in Medicine, 8, 836826. (doi: 10.3389/fmed.2021.836826) (PMID:35174189) (PMCID:PMC8841511)

Gestuveo, R. et al. (2022) Mutational analysis of Aedes aegypti Dicer 2 provides insights into the biogenesis of antiviral exogenous small interfering RNAs. PLoS Pathogens, 18(1), e1010202. (doi: 10.1371/journal.ppat.1010202) (PMID:34990484) (PMCID:PMC8769306)

Grass, V. et al. (2022) Adaptation to host cell environment during experimental evolution of Zika virus. Communications Biology, 5, 1115. (doi: 10.1038/s42003-022-03902-y) (PMID:36271143) (PMCID:PMC9587232)

2021

Silva, S. J. R. et al. (2021) Widespread contamination of SARS‐CoV-2 on highly touched surfaces in Brazil during the second wave of the COVID ‐19 pandemic. Environmental Microbiology, 23(12), pp. 7382-7395. (doi: 10.1111/1462-2920.15855) (PMID:34863010)

Mayanja, M. N., Mwiine, F. N., Lutwama, J. J., Ssekagiri, A., Egesa, M., Thomson, E. C. and Kohl, A. (2021) Mosquito-borne arboviruses in Uganda: history, transmission and burden. Journal of General Virology, 102(10), 001680. (doi: 10.1099/jgv.0.001680) (PMID:34609940)

Persson, B. D., Nord, S., Lindqvist, R., Danskog, K., Överby, A. K., Kohl, A. , Willison, H. J. , Lenman, A. and Arnberg, N. (2021) BAF45b Is required for efficient Zika virus infection of HAP1 cells. Viruses, 13(10), 2007. (doi: 10.3390/v13102007) (PMCID:PMC8540262)

Almire, F., Terhzaz, S. , Terry, S., McFarlane, M. , Gestuveo, R. J., Szemiel, A. M., Varjak, M. , McDonald, A., Kohl, A. and Pondeville, E. (2021) Sugar feeding protects against arboviral infection by enhancing gut immunity in the mosquito vector Aedes aegypti. PLoS Pathogens, 17(9), e1009870. (doi: 10.1371/journal.ppat.1009870) (PMID:34473801) (PMCID:PMC8412342)

Baksmeier, C. et al. (2021) Modified recombinant human IgG1-Fc is superior to natural intravenous immunoglobulin at inhibiting immune-mediated demyelination. Immunology, 164(1), pp. 90-105. (doi: 10.1111/imm.13341) (PMID:33880776) (PMCID:PMC8358725)

Szemiel, A. M. et al. (2021) In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2. PLoS Pathogens, 17(9), e1009929. (doi: 10.1371/journal.ppat.1009929) (PMID:34534263) (PMCID:PMC8496873)

Schultz, V. et al. (2021) Oligodendrocytes are susceptible to Zika virus infection in a mouse model of perinatal exposure: implications for CNS complications. Glia, 69(8), pp. 2023-2036. (doi: 10.1002/glia.24010) (PMID:33942402) (PMCID:PMC9216243)

Scherer, C. et al. (2021) An Aedes aegypti-derived Ago2 knockout cell line to investigate arbovirus infections. Viruses, 13(6), 1066. (doi: 10.3390/v13061066) (PMID:34205194) (PMCID:PMC8227176)

Mayanja, M. N., Mwiine, F., Lutwama, J. J., Sssekagiri, A., Egesa, M., Thomson, E. C. and Kohl, A. (2021) Mosquito-borne arboviruses in Uganda: history, transmission and burden. Journal of General Virology, 102(6), 001615. (doi: 10.1099/jgv.0.001615) (PMID:34166178)

McFarlane, M. , Laureti, M., Levée, T., Terry, S., Kohl, A. and Pondeville, E. (2021) Improved transient silencing of gene expression in the mosquito female Aedes aegypti. Insect Molecular Biology, 30(3), pp. 355-365. (doi: 10.1111/imb.12700) (PMID:33715239)

Gestuveo, R. J., Royle, J., Donald, C. L. , Lamont, D. J., Hutchinson, E. C. , Merits, A., Kohl, A. and Varjak, M. (2021) Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection. Nature Communications, 12, 2766. (doi: 10.1038/s41467-021-22966-8) (PMID:33986255) (PMCID:PMC8119459)

Rihn, S. J. et al. (2021) A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biology, 19(2), e3001091. (doi: 10.1371/journal.pbio.3001091) (PMID:33630831) (PMCID:PMC7906417)

Gallo, G. et al. (2021) Interactions of viral proteins from pathogenic and low or non-pathogenic orthohantaviruses with human type I interferon signaling. Viruses, 13(1), 140. (doi: 10.3390/v13010140) (PMID:33478127) (PMCID:PMC7835746)

Schultz, V. et al. (2021) Zika virus infection leads to demyelination and axonal injury in mature CNS cultures. Viruses, 13(1), 91. (doi: 10.3390/v13010091) (PMID:33440758) (PMCID:PMC7827345)

De Lorenzo, G. et al. (2021) Zika virus-like particles bearing covalent dimer of envelope protein protect mice from lethal challenge. Journal of Virology, 95(1), e01415-20. (doi: 10.1128/JVI.01415-20) (PMID:33028720) (PMCID:PMCID: PMC7737734)

Eifan, S., Hanif, A., Nour, I., Alqahtani, S., Eisa, Z. M., Dafalla, O. and Kohl, A. (2021) Distribution and molecular identification of Culex pipiens and Culex tritaeniorhynchus as potential vectors of Rift Valley fever virus in Jazan, Saudi Arabia. Pathogens, 10(10), 1334. (doi: 10.3390/pathogens10101334)

Hyde, K., Sultana, N., Tran, A. C., Bileckaja, N., Donald, C. L. , Kohl, A. , Stanton, R. J. and Strang, B. L. (2021) Limited replication of human cytomegalovirus in a trophoblast cell line. Journal of General Virology, 102(11), 001683. (doi: 10.1099/jgv.0.001683)

Parker, M. D. et al. (2021) Subgenomic RNA identification in SARS-CoV-2 genomic sequencing data. Genome Research, 31, pp. 645-658. (doi: 10.1101/gr.268110.120) (PMID:33722935) (PMCID:PMC8015849)

2020

Aubry, F. et al. (2020) Enhanced Zika virus susceptibility of globally invasive Aedes aegypti populations. Science, 370(6519), pp. 991-996. (doi: 10.1126/science.abd3663) (PMID:33214283)

Sanchez Velazquez, R. et al. (2020) Generation of a reporter yellow fever virus for high throughput antiviral assays. Antiviral Research, 183, 104939. (doi: 10.1016/j.antiviral.2020.104939) (PMID:32980446) (PMCID:PMC7649875)

Donald, C. L. , Siriyasatien, P. and Kohl, A. (2020) Toxorhynchites species: A review of current knowledge. Insects, 11(11), 747. (doi: 10.3390/insects11110747)

Clark, J. J., Gilray, J., Orton, R. J. , Baird, M., Wilkie, G., da Silva Filipe, A. , Johnson, N., McInnes, C. J., Kohl, A. and Biek, R. (2020) Population genomics of louping ill virus provide new insights into the evolution of tick-borne flaviviruses. PLoS Neglected Tropical Diseases, 14(9), e0008133. (doi: 10.1371/journal.pntd.0008133) (PMID:32925939) (PMCID:PMC7515184)

da Silva, S. J. R., da Silva, C. T. A., Guarines, K. M., Mendes, R. P. G., Pardee, K., Kohl, A. and Pena, L. (2020) Clinical and laboratory diagnosis of SARS-CoV-2, the virus causing COVID-19. ACS Infectious Diseases, 6(9), pp. 2319-2336. (doi: 10.1021/acsinfecdis.0c00274) (PMID:32786280) (PMCID:PMC7441751)

Varjak, M. , Gestuveo, R. J., Burchmore, R. , Schnettler, E. and Kohl, A. (2020) aBravo is a novel Aedes aegypti antiviral protein that interacts with, but acts independently of, the exogenous siRNA pathway effector Dicer 2. Viruses, 12(7), 748. (doi: 10.3390/v12070748)

Schilling, M., Bridgeman, A., Gray, N., Hertzog, J., Hublitz, P., Kohl, A. and Rehwinkel, J. (2020) RIG-I plays a dominant role in the induction of transcriptional changes in Zika virus-infected cells and protects from virus-induced cell death. Cells, 9(6), 1476. (doi: 10.3390/cells9061476)

Royle, J. , Ramírez-Santana, C., Akpunarlieva, S., Donald, C. L. , Gestuveo, R. J., Anaya, J.-M., Merits, A., Burchmore, R. , Kohl, A. and Varjak, M. (2020) Glucose-regulated protein 78 interacts with Zika virus envelope protein and contributes to a productive infection. Viruses, 12(5), 524. (doi: 10.3390/v12050524)

Parry, R. et al. (2020) Identification and RNAi profile of a novel iflavirus infecting Senegalese Aedes vexans arabiensis mosquitoes. Viruses, 12(4), e440. (doi: 10.3390/v12040440) (PMID:32295109)

McFarlane, M. et al. (2020) The Aedes aegypti Domino orthologue p400 regulates antiviral exogenous small interfering RNA pathway activity and ago-2 expression. mSphere, 5(2), e00081-20. (doi: 10.1128/mSphere.00081-20) (PMID:32269152) (PMCID:PMC7142294)

Alexander, A. J.T. et al. (2020) Development of a reverse genetics system for Toscana virus (lineage A). Viruses, 12(4), 411. (doi: 10.3390/v12040411)

Mayanja, M. N., Mwiine, F. N., Kohl, A. , Thomson, E. C. and Lutwama, J. J. (2020) An update on the mosquito species composition and diversity in western and North Western Uganda. Journal of Entomology and Zoology Studies, 8(2), pp. 1074-1086.

Pezzi, L. et al. (2020) GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 5: entomological aspects. Antiviral Research, 174, 104670. (doi: 10.1016/j.antiviral.2019.104670) (PMID:31812638)

Ortega-López, L. D. , Pondeville, E., Kohl, A. , León, R., Pazmino Betancourth, M. , Almire, F., Torres-Valencia, S., Saldarriaga, S., Mirzai, N. and Ferguson, H. M. (2020) The mosquito electrocuting trap as an exposure-free method for measuring human-biting rates by Aedes mosquito vectors. Parasites and Vectors, 13, 31. (doi: 10.1186/s13071-020-3887-8) (PMID:31941536) (PMCID:PMC6961254)

Silva, S. J. R. d., Germano Mendes, R. P., Alves da Silva, C. T., Lorusso, A., Kohl, A. and Pena, L. (2020) Insights into SARS-CoV-2, the coronavirus underlying COVID-19: recent genomic data and the development of reverse genetics systems. Journal of General Virology, 101(10), pp. 1021-1024. (doi: 10.1099/jgv.0.001458) (PMID:32579100) (PMCID:PMC7660456)

2019

Tykalová, H., Selinger, M., Štěrba, J., Vavrušková, Z., Věchtová, P., Lieskovská, J., Kohl, A. , Schnettler, E. and Grubhoffer, L. (2019) Tick-borne encephalitis virus inhibits rRNA synthesis and host protein production in human cells of neural origin. PLoS Neglected Tropical Diseases, 13(9), e0007745. (doi: 10.1371/journal.pntd.0007745) (PMID:31560682) (PMCID:PMC6785130)

Kendall, C., Khalid, H., Müller, M., Banda, D. H., Kohl, A. , Merits, A., Stonehouse, N. J. and Tuplin, A. (2019) Structural and phenotypic analysis of Chikungunya virus RNA replication elements. Nucleic Acids Research, 47(17), pp. 9396-9312. (doi: 10.1093/nar/gkz640) (PMID:31350895) (PMCID:PMC6753490)

Modha, S. , Hughes, J. , Bianco, G., Ferguson, H. M. , Helm, B., Tong, L., Wilkie, G. S., Kohl, A. and Schnettler, E. (2019) Metaviromics reveals unknown viral diversity in the biting midge Culicoides impunctatus. Viruses, 11(9), 865. (doi: 10.3390/v11090865) (PMID:31533247) (PMCID:PMC6784199)

Lima, M. C. et al. (2019) The transcriptional and protein profile from human infected neuroprogenitor cells is strongly correlated to Zika virus microcephaly cytokines phenotype evidencing a persistent inflammation in the CNS. Frontiers in Immunology, 10, 1928. (doi: 10.3389/fimmu.2019.01928) (PMID:31474994) (PMCID:PMC6707094)

Ayers, V. B., Huang, Y.-J. S., Lyons, A. C., Park, S. L., Dunlop, J. I., Unlu, I., Kohl, A. , Higgs, S., Blitvich, B. J. and Vanlandingham, D. L. (2019) Infection and transmission of Cache Valley virus by Aedes albopictus and Aedes aegypti mosquitoes. Parasites and Vectors, 12(1), 384. (doi: 10.1186/s13071-019-3643-0) (PMID:31366369) (PMCID:PMC6670168)

Pezzi, L. et al. (2019) GloPID-R report on Chikungunya, O'nyong-nyong and Mayaro virus, part I: biological diagnostics. Antiviral Research, 166, pp. 66-81. (doi: 10.1016/j.antiviral.2019.03.009) (PMID:30905821)

Yen, P.-S., Chen, C.-H., Sreenu, V. , Kohl, A. and Failloux, A.-B. (2019) Assessing the potential interactions between cellular miRNA and arboviral genomic RNA in the Yellow Fever mosquito, Aedes aegypti. Viruses, 11(6), 540. (doi: 10.3390/v11060540) (PMID:31185697) (PMCID:PMC6631873)

Rezelj, V. V., Mottram, T. J., Hughes, J. , Elliott, R. M., Kohl, A. and Brennan, B. (2019) M segment-based minigenomes and virus-like particle assays as an approach to assess the potential of tick-borne Phlebovirus genome reassortment. Journal of Virology, 93(6), e02068-18. (doi: 10.1128/JVI.02068-18) (PMID:30567991) (PMCID:PMC6401446)

Zhuang, X. et al. (2019) The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication. Nature Communications, 10, (doi: 10.1038/s41467-019-08299-7) (PMID:30670689) (PMCID:PMC6343007)

2018

Donald, C. L. , Varjak, M. , Aguiar, E. R. G. R., Marques, J. T., Sreenu, V. B. , Schnettler, E. and Kohl, A. (2018) Antiviral RNA interference activity in cells of the predatory mosquito, Toxorhynchites amboinensis. Viruses, 10(12), 694. (doi: 10.3390/v10120694) (PMID:30563205) (PMCID:PMC6316411)

Dunlop, J. I. et al. (2018) Development of reverse genetics systems and investigation of host response antagonism and reassortment potential for Cache Valley and Kairi viruses, two emerging orthobunyaviruses of the Americas. PLoS Neglected Tropical Diseases, 12(10), e0006884. (doi: 10.1371/journal.pntd.0006884) (PMID:30372452) (PMCID:PMC6245839)

Campos, T. D. L., Durães-Carvalho, R., Rezende, A. M., de Carvalho, O. V., Kohl, A. , Wallau, G. L. and Pena, L. J. (2018) Revisiting key entry routes of human epidemic arboviruses into the mainland Americas through large-scale phylogenomics. International Journal of Genomics, 2018, 6941735. (doi: 10.1155/2018/6941735) (PMID:30402454) (PMCID:PMC6196792)

Ayers, V. B. et al. (2018) Culex tarsalis is a competent vector species for Cache Valley virus. Parasites and Vectors, 11, 519. (doi: 10.1186/s13071-018-3103-2) (PMID:30236148) (PMCID:PMC6149065)

Selinger, M., Wilkie, G. S., Tong, L., Gu, Q. , Schnettler, E., Grubhoffer, L. and Kohl, A. (2018) Corrigendum: Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection. Journal of General Virology, 99(8), pp. 1147-1149. (doi: 10.1099/jgv.0.001109) (PMID:30067173)

Hertzog, J. et al. (2018) Infection with a Brazilian isolate of Zika virus generates RIG‐I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signalling. European Journal of Immunology, 48(7), pp. 1120-1136. (doi: 10.1002/eji.201847483) (PMID:29572905) (PMCID:PMC6055886)

López-Camacho, C. et al. (2018) Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors. Nature Communications, 9, 2441. (doi: 10.1038/s41467-018-04859-5) (PMID:29934593) (PMCID:PMC6015009)

Dickson, L. B. et al. (2018) Diverse laboratory colonies of Aedes aegypti harbor the same adult midgut bacterial microbiome. Parasites and Vectors, 11, 207. (doi: 10.1186/s13071-018-2780-1) (PMID:29587819) (PMCID:PMC587006)

Zmurko, J., Vasey, D. B., Donald, C. L. , Armstrong, A. A., McKee, M. L., Kohl, A. and Clayton, R. F. (2018) Mitigating the risk of Zika virus contamination of raw materials and cell lines in the manufacture of biologicals. Journal of General Virology, 99, pp. 219-229. (doi: 10.1099/jgv.0.000995) (PMID:29239715) (PMCID:PMC5882083)

Varjak, M. , Dietrich, I., Sreenu, V. B. , Till, B. E., Merits, A., Kohl, A. and Schnettler, E. (2018) Spindle-E acts antivirally against alphaviruses in mosquito cells. Viruses, 10(2), 88. (doi: 10.3390/v10020088) (PMID:29463033) (PMCID:PMC5850395)

Hover, S., Foster, B., Fontana, J., Kohl, A. , Goldstein, S. A.N., Barr, J. N. and Mankouri, J. (2018) Bunyavirus requirement for endosomal K+ reveals new roles of cellular ion channels during infection. PLoS Pathogens, 14(1), e1006845. (doi: 10.1371/journal.ppat.1006845) (PMID:29352299) (PMCID:PMC5805358)

Lourenço-de-Oliveira, R., Marques, J. T., Sreenu, V. B. , Nten, C. A., Guimarães Rocha Aguiarr, E. R., Varjak, M. , Kohl, A. and Failloux, A.-B. (2018) Culex quinquefasciatus mosquitoes do not support replication of Zika virus. Journal of General Virology, 99, pp. 258-264. (doi: 10.1099/jgv.0.000949) (PMID:29076805) (PMCID:PMC5882084)

2017

Royle, J., Donald, C. L. , Merits, A., Kohl, A. and Varjak, M. (2017) Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses. Veterinary Journal, 230, pp. 62-64. (doi: 10.1016/j.tvjl.2017.10.009) (PMID:29102599) (PMCID:PMC5726355)

Varjak, M. , Donald, C. L. , Mottram, T. J., Sreenu, V. B. , Merits, A., Maringer, K., Schnettler, E. and Kohl, A. (2017) Characterization of the Zika virus induced small RNA response in Aedes aegypti cells. PLoS Neglected Tropical Diseases, 11(10), e0006010. (doi: 10.1371/journal.pntd.0006010) (PMID:29040304) (PMCID:PMC5667879)

Selinger, M., Wilkie, G. S., Tong, L., Gu, Q. , Schnettler, E., Grubhoffer, L. and Kohl, A. (2017) Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection. Journal of General Virology, 98(8), pp. 2043-2060. (doi: 10.1099/jgv.0.000853) (PMID:28786780)

Cumberworth, S. L. et al. (2017) Zika virus tropism and interactions in myelinating neural cell cultures: CNS cells and myelin are preferentially affected. Acta Neuropathologica Communications, 5, 50. (doi: 10.1186/s40478-017-0450-8) (PMID:28645311) (PMCID:PMC5481922)

Cumberworth, S., Clark, J. J., Kohl, A. and Donald, C. L. (2017) Inhibition of type I interferon induction and signalling by mosquito-borne flaviviruses. Cellular Microbiology, 19(5), e12737. (doi: 10.1111/cmi.12737) (PMID:28273394) (PMCID:PMC5413821)

Dietrich, I. et al. (2017) RNA interference restricts rift valley fever virus in multiple insect systems. mSphere, 2(3), 00090-17. (doi: 10.1128/mSphere.00090-17) (PMID:28497117) (PMCID:PMC5415632)

Varjak, M. et al. (2017) Aedes aegypti Piwi4 is a noncanonical PIWI protein involved in antiviral responses. mSphere, 2(3), 00144-17. (doi: 10.1128/mSphere.00144-17) (PMID:28497119) (PMCID:PMC5415634)

Burt, F. J. et al. (2017) Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen. Lancet Infectious Diseases, 17(4), e107-e117. (doi: 10.1016/S1473-3099(16)30385-1) (PMID:28159534)

Dietrich, I., Shi, X. , McFarlane, M. , Watson, M., Blomström, A.-L., Skelton, J. K., Kohl, A. , Elliott, R. M. and Schnettler, E. (2017) The antiviral RNAi response in vector and non-vector cells against orthobunya viruses. PLoS Neglected Tropical Diseases, 11(1), e0005272. (doi: 10.1371/journal.pntd.0005272) (PMID:28060823) (PMCID:PMC5245901)

Mottram, T. J., Li, P. , Dietrich, I., Shi, X. , Brennan, B. , Varjak, M. and Kohl, A. (2017) Mutational analysis of Rift Valley fever phlebovirus nucleocapsid protein indicates novel conserved, functional amino acids. PLoS Neglected Tropical Diseases, 11(12), e0006155. (doi: 10.1371/journal.pntd.0006155) (PMID:29267287) (PMCID:PMC5764413)

2016

Donald, C. L. et al. (2016) Full genome sequence and sfRNA interferon antagonist activity of Zika virus from Recife, Brazil. PLoS Neglected Tropical Diseases, 10(10), e0005048. (doi: 10.1371/journal.pntd.0005048) (PMID:27706161) (PMCID:PMC5051680)

Wijayanti, S. P. M., Porphyre, T., Chase-Topping, M., Rainey, S. M., McFarlane, M. , Schnettler, E., Biek, R. and Kohl, A. (2016) The importance of socio-economic versus environmental risk factors for reported dengue cases in Java, Indonesia. PLoS Neglected Tropical Diseases, 10(9), e0004964. (doi: 10.1371/journal.pntd.0004964) (PMID:27603137) (PMCID:PMC5014450)

Kohl, A. , Brennan, B. and Weber, F. (2016) Homage to Richard M. Elliott. Viruses, 8(8), 224. (doi: 10.3390/v8080224) (PMID:27517952) (PMCID:PMC4997586)

Pingen, M. , Bryden, S. R. , Pondeville, E., Schnettler, E., Kohl, A. , Merits, A., Fazakerley, J. K., Graham, G. J. and McKimmie, C. S. (2016) Host inflammatory response to mosquito bites enhances the severity of arbovirus infection. Immunity, 44(6), pp. 1455-1469. (doi: 10.1016/j.immuni.2016.06.002) (PMID:27332734) (PMCID:PMC4920956)

Rainey, S. M. et al. (2016) Wolbachia blocks viral genome replication early in infection without a transcriptional response by the endosymbiont or host small RNA pathways. PLoS Pathogens, 12(4), e1005536. (doi: 10.1371/journal.ppat.1005536) (PMID:27089431) (PMCID:PMC4835223)

Hover, S. et al. (2016) Modulation of potassium channels inhibits bunyavirus infection. Journal of Biological Chemistry, 291(7), pp. 3411-3422. (doi: 10.1074/jbc.M115.692673) (PMID:26677217) (PMCID:PMC4751384)

Gatherer, D. and Kohl, A. (2016) Zika virus: a previously slow pandemic spreads rapidly through the Americas. Journal of General Virology, 97, pp. 269-273. (doi: 10.1099/jgv.0.000381) (PMID:26684466)

McFarlane, M. and Kohl, A. (2016) Alphaviruses and their role in elucidating antiviral responses in mosquitoes. In: Mahalingam, S., Herrero, L. and Herring, B. (eds.) Alphaviruses: Current Biology. Caister Academic Press, pp. 77-88. ISBN 9781910190159 (doi: 10.21775/9781910190159.05)

Kohl, A. et al. (2016) Advancing vector biology research: a community survey for future directions, research applications and infrastructure requirements. Pathogens and Global Health, 110(4-5), pp. 164-172. (doi: 10.1080/20477724.2016.1211475) (PMID:27677378) (PMCID:PMC5072118)

Ndiaye, E. H. et al. (2016) Vector competence of Aedes vexans (Meigen), Culex poicilipes (Theobald) and Cx. quinquefasciatus Say from Senegal for West and East African lineages of Rift Valley fever virus. Parasites and Vectors, 9, 94. (doi: 10.1186/s13071-016-1383-y) (PMID:26897521) (PMCID:PMC4761212)

Wijayanti, S. P. M., Sunaryo, S., Suprihatin, S., McFarlane, M. , Rainey, S. M., Dietrich, I., Schnettler, E., Biek, R. and Kohl, A. (2016) Dengue in Java, Indonesia: relevance of mosquito indices as risk predictors. PLoS Neglected Tropical Diseases, 10(3), e0004500. (doi: 10.1371/journal.pntd.0004500) (PMID:26967524) (PMCID:PMC4788303)

2015

Brennan, B. et al. (2015) In memoriam – Richard M. Elliott (1954–2015). Journal of General Virology, 96(8), pp. 1975-1978. (doi: 10.1099/jgv.0.000241) (PMID:26315040)

Blomström, A.-L. et al. (2015) Transcriptome analysis reveals the host response to Schmallenberg virus in bovine cells and antagonistic effects of the NSs protein. BMC Genomics, 16, 324. (doi: 10.1186/s12864-015-1538-9) (PMID:25896169) (PMCID:PMC4404599)

Carissimo, G. et al. (2015) Antiviral immunity of Anopheles gambiaeis highly compartmentalized, with distinct roles for RNA interference and gut microbiota. Proceedings of the National Academy of Sciences of the United States of America, 112(2), E176-E185. (doi: 10.1073/pnas.1412984112) (PMID:25548172) (PMCID:PMC4299212)

Kean, J., Rainey, S., McFarlane, M. , Donald, C. , Schnettler, E., Kohl, A. and Pondeville, E. (2015) Fighting arbovirus transmission: natural and engineered control of vector competence in aedes mosquitoes. Insects, 6(1), pp. 236-278. (doi: 10.3390/insects6010236) (PMID:26463078) (PMCID:PMC4553541)

2014

Barry, G. et al. (2014) NSs protein of Schmallenberg virus counteracts the antiviral response of the cell by inhibiting its transcriptional machinery. Journal of General Virology, 95(Pt. 8), pp. 1640-1646. (doi: 10.1099/vir.0.065425-0)

McFarlane, M. et al. (2014) Characterization of Aedes aegypti innate-immune pathways that limit Chikungunya virus replication. PLoS Neglected Tropical Diseases, 8(7), e2994. (doi: 10.1371/journal.pntd.0002994) (PMID:25058001) (PMCID:PMC4109886)

Moniuszko, A., Rückert, C., Alberdi, M. P., Barry, G., Stevenson, B., Fazakerley, J. K., Kohl, A. and Bell-Sakyi, L. (2014) Coinfection of tick cell lines has variable effects on replication of intracellular bacterial and viral pathogens. Ticks and Tick-borne Diseases, 5(4), pp. 415-422. (doi: 10.1016/j.ttbdis.2014.01.010)

Rainey, S. M., Shah, P., Kohl, A. and Dietrich, I. (2014) Understanding the Wolbachia-mediated inhibition of arboviruses in mosquitoes: progress and challenges. Journal of General Virology, 95(3), pp. 517-530. (doi: 10.1099/vir.0.057422-0) (PMID:24343914)

Schnettler, E. et al. (2014) Induction and suppression of tick cell antiviral RNAi responses by tick-borne flaviviruses. Nucleic Acids Research, 42(14), pp. 9436-9446. (doi: 10.1093/nar/gku657)

2013

Watson, M., Schnettler, E. and Kohl, A. (2013) viRome: an R package for the visualization and analysis of viral small RNA sequence datasets. Bioinformatics, 29(15), pp. 1902-1903. (doi: 10.1093/bioinformatics/btt297) (PMID:23709497) (PMCID:PMC3712215)

Schnettler, E., Donald, C. L. , Human, S., Watson, M., Siu, R. W. C., McFarlane, M. , Fazakerley, J. K., Kohl, A. and Fragkoudis, R. (2013) Knockdown of piRNA pathway proteins results in enhanced Semliki forest virus production in mosquito cells. Journal of General Virology, 94(Pt. 7), pp. 1680-1689. (doi: 10.1099/vir.0.053850-0) (PMID:23559478) (PMCID:PMC3709635)

Barry, G., Alberdi, P., Schnettler, E., Weisheit, S., Kohl, A. , Fazakerley, J.K. and Bell-Sakyi, L. (2013) Gene silencing in tick cell lines using small interfering or long double-stranded RNA. Experimental and Applied Acarology, 59(3), pp. 319-338. (doi: 10.1007/s10493-012-9598-x)

Schnettler, E., Ratinier, M., Watson, M., Shaw, A. E., McFarlane, M., Varela, M., Elliott, R. M., Palmarini, M. and Kohl, A. (2013) RNA interference targets arbovirus replication in Culicoides cells. Journal of Virology, 87(5), pp. 2441-2454. (doi: 10.1128/JVI.02848-12) (PMID:23269795) (PMCID:PMC3571378)

Eifan, S., Schnettler, E., Dietrich, I., Kohl, A. and Blomstrom, A. (2013) Non-structural proteins of arthropod-borne bunyaviruses: roles and functions. Viruses, 5(10), pp. 2447-2468. (doi: 10.3390/v5102447)

Varela, M. et al. (2013) Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host. PLoS Pathogens, 9(1), e1003133. (doi: 10.1371/journal.ppat.1003133) (PMID:23326235) (PMCID:PMC3542112)

2012

Schnettler, E., Sterken, M. G., Leung, J. Y., Metz, S. W., Geertsema, C., Goldbach, R. W., Vlak, J. M., Kohl, A. , Khromykh, A. A.. and Pijlman, G. P. (2012) Noncoding flavivirus RNA displays RNA interference suppressor activity in insect and mammalian cells. Journal of Virology, 86(24), pp. 13486-13500. (doi: 10.1128/JVI.01104-12) (PMID:23035235) (PMCID:PMC3503047)

Donald, C. L. , Kohl, A. and Schnettler, E. (2012) New insights into control of arbovirus replication and spread by insect RNA interference pathways. Insects, 3(2), pp. 511-531. (doi: 10.3390/insects3020511)

Alberdi, M.P., Dalby, M.J. , Rodriguez-Andres, J., Fazakerley, J.K., Kohl, A. and Bell-Sakyi, L. (2012) Detection and identification of putative bacterial endosymbionts and endogenous viruses in tick cell lines. Ticks and Tick-borne Diseases, 3(3), pp. 137-146. (doi: 10.1016/j.ttbdis.2012.05.002)

Bell-Sakyi, L., Kohl, A. , Bente, D.A. and Fazakerley, J.K. (2012) Tick cell lines for study of Crimean-Congo hemorrhagic fever virus and other arboviruses. Vector-Borne and Zoonotic Diseases, 12(9), pp. 769-781. (doi: 10.1089/vbz.2011.0766)

Rodriguez-Andres, J. et al. (2012) Phenoloxidase activity acts as a mosquito innate immune response against infection with semliki forest virus. PLoS Pathogens, 8(11), e1002977. (doi: 10.1371/journal.ppat.1002977) (PMID:23144608) (PMCID:PMC3493465)

2011

Siu, R. W.C. et al. (2011) Antiviral RNA interference responses induced by Semliki Forest virus infection of mosquito cells: characterization, origin, and frequency-dependent functions of virus-derived small interfering RNAs. Journal of Virology, 85(6), pp. 2907-2917. (doi: 10.1128/JVI.02052-10)

2010

Santhakumar, D. et al. (2010) Combined agonist-antagonist genome-wide functional screening identifies broadly active antiviral microRNAs. Proceedings of the National Academy of Sciences of the United States of America, 107(31), pp. 13830-13835. (doi: 10.1073/pnas.1008861107)

Barry, G., Fragkoudis, R., Ferguson, M.C., Lulla, A., Merits, A., Kohl, A. and Fazakerley, J.K. (2010) Semliki Forest Virus-induced endoplasmic reticulum stress accelerates apoptotic death of mammalian cells. Journal of Virology, 84(14), pp. 7369-7377. (doi: 10.1128/JVI.02310-09)

Mankouri, J., Fragkoudis, R., Richards, K.H., Wetherill, L.F., Harris, M., Kohl, A. , Elliott, R.M. and Macdonald, A. (2010) Optineurin negatively regulates the induction of IFNβ in response to RNA virus infection. PLoS Pathogens, 6(2), e1000778. (doi: 10.1371/journal.ppat.1000778)

2009

Attarzadeh-Yazdi, G. et al. (2009) Cell-to-cell Spread of the RNA interference response suppresses Semliki Forest Virus (SFV) infection of mosquito cell cultures and cannot be antagonized by SFV. Journal of Virology, 83(11), pp. 5735-5748. (doi: 10.1128/JVI.02440-08)

Barry, G., Breakwell, L., Fragkoudis, R., Attarzadeh-Yazdi, G., Rodriguez-Andres, J., Kohl, A. and Fazakerley, J.K. (2009) PKR acts early in infection to suppress Semliki Forest virus production and strongly enhances the type I interferon response. Journal of General Virology, 90(6), pp. 1382-1391. (doi: 10.1099/vir.0.007336-0)

Fragkoudis, R., Attarzadeh-Yazdi, G., Nash, A.A., Fazakerley, J.K. and Kohl, A. (2009) Advances in dissecting mosquito innate immune responses to arbovirus infection. Journal of General Virology, 90(9), pp. 2061-2072. (doi: 10.1099/vir.0.013201-0)

Fragkoudis, R., Tamberg, N., Siu, R., Kiiver, K., Kohl, A. , Merits, A. and Fazakerley, J.K. (2009) Neurons and oligodendrocytes in the mouse brain differ in their ability to replicate Semliki Forest virus. Journal of Neurovirology, 15(1), pp. 57-70. (doi: 10.1080/13550280802482583)

Hart, T.J., Kohl, A. and Elliott, R.M. (2009) Role of the NSs protein in the zoonotic capacity of Orthobunyaviruses. Zoonoses and Public Health, 56(6-7), pp. 285-296. (doi: 10.1111/j.1863-2378.2008.01166.x)

2008

Fragkoudis, R., Chi, Y., Siu, R.W.C., Barry, G., Attarzadeh-Yazdi, G., Merits, A., Nash, A.A., Fazakerley, J.K. and Kohl, A. (2008) Semliki Forest virus strongly reduces mosquito host defence signaling. Insect Molecular Biology, 17(6), pp. 647-656. (doi: 10.1111/j.1365-2583.2008.00834.x)

2007

Fragkoudis, R., Breakwell, L., McKimmie, C., Boyd, A., Barry, G., Kohl, A. , Merits, A. and Fazakerley, J. K. (2007) The type I interferon system protects mice from Semliki Forest virus by preventing widespread virus dissemination in extraneural tissues, but does not mediate the restricted replication of avirulent virus in central nervous system neurons. Journal of General Virology, 88(12), pp. 3373-3384. (doi: 10.1099/vir.0.83191-0)

Blakqori, G. et al. (2007) La Crosse Bunyavirus nonstructural protein NSs serves to suppress the type I interferon system of mammalian hosts. Journal of Virology, 81(10), pp. 4991-4999. (doi: 10.1128/JVI.01933-06)

Shi, X. , Kohl, A. and Elliott, R.M. (2007) Role of the cytoplasmic tail domains of Bunyamwera orthobunyavirus glycoproteins Gn and Gc in virus assembly and morphogenesis. Journal of Virology, 81(18), pp. 10151-10160. (doi: 10.1128/JVI.00573-07)

2006

Léonard, V.H.J., Kohl, A. , Hart, T.J. and Elliott, R.M. (2006) Interaction of Bunyamwera Orthobunyavirus NSs protein with mediator protein MED8: a mechanism for inhibiting the interferon response. Journal of Virology, 80(19), pp. 9667-9675. (doi: 10.1128/JVI.00822-06)

Kohl, A. , Lowen, A.C., Leonard, V.H.J. and Elliott, R.M. (2006) Genetic elements regulating packaging of the Bunyamwera orthobunyavirus genome. Journal of General Virology, 87, pp. 177-187.

Shi, X. , Kohl, A. , Leonard, V.H.J., Li, P., McLees, A. and Elliott, R.M. (2006) Requirement of the N-terminal region of orthobunyavirus nonstructural protein NSm for virus assembly and morphogenesis. Journal of Virology, 80(16), pp. 8089-8099. (doi: 10.1128/JVI.00579-06)

2005

Leonard, V.H.J., Kohl, A. , Osborne, J.C., McLees, A. and Elliott, R.M. (2005) Homotypic interaction of Bunyamwera virus nucleocapsid protein. Journal of Virology, 79(20), pp. 13166-13172. (doi: 10.1128/JVI.79.20.13166-13172.2005)

2004

Kohl, A. , Dunn, E.F., Lowen, A.C. and Elliott, R.M. (2004) Complementarity, sequence and structural elements within the 3' and 5' non-coding regions of the Bunyamwera orthobunyavirus S segment determine promoter strength. Journal of General Virology, 85(11), pp. 3269-3278. (doi: 10.1099/vir.0.80407-0)

Billecocq, A., Spiegel, M., Vialat, P., Kohl, A. , Weber, F., Bouloy, M. and Haller, O. (2004) NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcription. Journal of Virology, 78(18), pp. 9798-9806. (doi: 10.1128/JVI.78.18.9798-9806.2004)

Elliott, R.M. and Kohl, A. (2004) Bunyavirus/mosquito interactions. In: Gillespie, S.H., Smith, G.L. and Osbourn, A.E. (eds.) Microbe-Vector Interactions in Vector-Borne Diseases. Series: Symposia of the Society for General Microbiology (63). Cambridge University Press: Cambridge, UK, pp. 91-102. ISBN 9780521843126

Kohl, A. , Dunn, E.F., Lowen, A.C. and Elliott, R.M. (2004) Complementarity, sequence and structural elements within the 3 ' and 5 ' non-coding regions of the Bunyamwera orthobunyavirus S segment determine promoter strength. Journal of General Virology, 85, pp. 3269-3278. (doi: 10.1099/vir.0.80407-0)

Kohl, A. , Hart, T.J., Noonan, C., Royall, E., Roberts, L.O. and Elliott, R.M. (2004) A Bunyamwera virus minireplicon system in mosquito cells. Journal of Virology, 78, pp. 5679-5685. (doi: 10.1128/JVI.78.11.5679-5685.2004)

2003

Kohl, A. , Bridgen, A., Dunn, E., Barr, J.N. and Elliott, R.M. (2003) Effects of a point mutation in the 3 ' end of the S genome segment of naturally occurring and engineered Bunyamwera viruses. Journal of General Virology, 84, pp. 789-793. (doi: 10.1099/vir.0.18963-0)

Kohl, A. , Bridgen, A., Dunn, E., Barr, J.N. and Elliott, R.M. (2003) Effects of a point mutation in the 3' end of the S genome segment of naturally occurring and engineered Bunyamwera viruses. Journal of General Virology, 84(4), pp. 789-793. (doi: 10.1099/vir.0.18963-0)

Kohl, A. , Clayton, R.F., Weber, F., Bridgen, A., Randall, R.E. and Elliott, R.M. (2003) Bunyamwera virus nonstructural protein NSs counteracts interferon regulatory factor 3-mediated induction of early cell death. Journal of Virology, 77, pp. 7999-8008. (doi: 10.1128/JVI.77.14.7999-8008.2003)

2000

Vialat, P., Billecocq, A., Kohl, A. and Bouloy, M. (2000) The S segment of Rift Valley fever Phlebovirus (Bunyaviridae) carries determinants for attenuation and virulence in mice. Journal of Virology, 74(3), pp. 1538-1543. (doi: 10.1128/JVI.74.3.1538-1543.2000)

1999

Kohl, A. , di Bartolo, V. and Bouloy, M. (1999) The Rift Valley fever virus nonstructural protein NSs is phosphorylated at serine residues located in casein kinase II consensus motifs in the carboxy-terminus. Virology, 263(2), pp. 517-525. (doi: 10.1006/viro.1999.9978)

Yadani, F.Z., Kohl, A. , Préhaud, C., Billecocq, A. and Bouloy, M. (1999) The carboxy-terminal acidic domain of Rift Valley Fever virus NSs protein is essential for the formation of filamentous structures but not for the nuclear localization of the protein. Journal of Virology, 73(6), pp. 5018-5025.

Kroll, M., Margottin, F., Kohl, A. , Renard, P., Durand, H., Concordet, J., Bachelerie, F., Arenzana-Seisdedos, F. and Benarous, R. (1999) Inducible degradation of Ikappa Balpha by the proteasome requires interaction with the F-box protein h-beta TrCP. Journal of Biological Chemistry, 274(12), pp. 7941-7945. (doi: 10.1074/jbc.274.12.7941)

Kohl, A. , Billecocq, A., Prehaud, C., Yadani, F.Z. and Bouloy, M. (1999) Transient gene expression in mammalian and mosquito cells using a recombinant Semliki Forest virus expressing T7 RNA polymerase. Applied Microbiology and Biotechnology, 53(1), pp. 51-56. (doi: 10.1007/s002530051613)

1997

Kohl, A. , Wittchen, K.-D. and Meinhardt, F. (1997) Rapid method for cloning a Ca(2+)-dependent metalloprotease from a gram-positive bacterium in Escherichia coli. BioTechniques, 22(1), pp. 58-59.

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