Dr Affar Karimullah

  • Research Fellow (School of Chemistry)

Research interests

Research Interests: My interest is to innovate new sensors for life science applications. Previously I have worked on using conducting polymers for in-situ detection of cell growth and stem cell differentiation to aid large scale cell culture activities. My current interests lie in the use of optical techniques to perform diagnostics and improve our capabilities for precision medicine. As part of my EPSRC UKRI Innovation Fellowship, I aim to use chiral nano-patterned gold surfaces to create biostructure sensitive assays that are able to detect serious medical conditions such as Sepsis and Invasive Aspergillosis in shorter periods of time and outside a laboratory setting. These Chiral Plasmonic Assayswill use technology pioneered in Glasgow, specifically, low cost Disposable Plasmonicsand Chiral Plasmonic Sensingthat will enable a commercially realisable technological breakthrough. 

My multidisciplinary group encompasses the fields of nanotechnology, optical instrument design, biochemistry and biomedical engineering. We create novel microscopy systems and metamaterials to push the boundaries of biosensing. Research commercialisation and impact is fundamental to our activity. Hence, industrial collaborations with HORIBA Scientific and Avacta Lifesciences are an important aspect to fulfilling the research and impact activities.

plasmic response and conformational change illustrative diagram


Research datasets

Jump to: 2018 | 2015
Number of items: 2.

2018

Paterson, G., Karimullah, A. , Smith, S., Kadodwala, M. and MacLaren, D. (2018) Symmetry Reduction and Shape Effects in Concave Chiral Plasmonic Structures. [Data Collection]

2015

Paterson, G., Karimullah, A. , Williamson, S. D. R., Kadodwala, M. and MacLaren, D. (2015) Electron energy loss spectroscopy of a chiral plasmonic structure. [Data Collection]

This list was generated on Fri Jul 19 07:16:09 2019 BST.

Publications

List by: Type | Date

Jump to: 2019 | 2018 | 2017 | 2016 | 2015 | 2013
Number of items: 12.

2019

Gilroy, C., Hashiyada, S., Endo, K., Karimullah, A. S. , Barron, L., Okamoto, H., Togawa, Y. and Kadodwala, M. (2019) Roles of superchirality and interference in chiral plasmonic biodetection. Journal of Physical Chemistry C, (doi:10.1021/acs.jpcc.9b02791) (Early Online Publication)

2018

Kelly, C., Tullius, R., Lapthorn, A. J. , Gadegaard, N. , Cooke, G. , Barron, L. D., Karimullah, A. S. , Rotello, V. M. and Kadodwala, M. (2018) Chiral plasmonic fields probe structural order of biointerfaces. Journal of the American Chemical Society, 140(27), pp. 8509-8517. (doi:10.1021/jacs.8b03634) (PMID:29909628)

Paterson, G. W. , Karimullah, A. S. , Smith, S. G., Kadodwala, M. and MacLaren, D. A. (2018) Symmetry reduction and shape effects in concave chiral plasmonic structures. Journal of Physical Chemistry C, 122(9), pp. 5049-5056. (doi:10.1021/acs.jpcc.7b12260)

Kelly, C., Khorashad, L. K., Gadegaard, N. , Barron, L. D., Govorov, A. O., Karimullah, A. S. and Kadodwala, M. (2018) Controlling metamaterial transparency with superchiral fields. ACS Photonics, 5(2), pp. 535-543. (doi:10.1021/acsphotonics.7b01071)

2017

Tullius, R. et al. (2017) Superchiral plasmonic phase sensitivity for fingerprinting of protein interface structure. ACS Nano, 11(12), pp. 12049-12056. (doi:10.1021/acsnano.7b04698) (PMID:29220155)

2016

Jack, C., Karimullah, A. S. , Leyman, R., Tullius, R., Rotello, V. M., Cooke, G. , Gadegaard, N. , Barron, L. D. and Kadodwala, M. (2016) Biomacromolecular stereostructure mediates mode hybridization in chiral plasmonic nanostructures. Nano Letters, 16(9), pp. 5806-5814. (doi:10.1021/acs.nanolett.6b02549) (PMID:27547978)

Jack, C. et al. (2016) Spatial control of chemical processes on nanostructures through nano-localized water heating. Nature Communications, 7, 10946. (doi:10.1038/ncomms10946) (PMID:26961708) (PMCID:PMC4792951)

2015

Karimullah, A. S. , Jack, C., Tullius, R., Rotello, V. M., Cooke, G. , Gadegaard, N. , Barron, L. D. and Kadodwala, M. (2015) Disposable plasmonics: plastic templated plasmonic metamaterials with tunable chirality. Advanced Materials, 27(37), pp. 5610-5616. (doi:10.1002/adma.201501816)

Paterson, G. W. , Karimullah, A. , Williamson, S. D. R., Kadodwala, M. and MacLaren, D. A. (2015) Electron energy loss spectroscopy of a chiral plasmonic structure. Journal of Physics: Conference Series, 644(1), 012005. (doi:10.1088/1742-6596/644/1/012005)

Tullius, R., Karimullah, A. S. , Rodier, M., Fitzpatrick, B., Gadegaard, N. , Barron, L. D., Rotello, V. M., Cooke, G. , Lapthorn, A. and Kadodwala, M. (2015) "Superchiral” spectroscopy: detection of protein higher order hierarchical structure with chiral plasmonic nanostructures. Journal of the American Chemical Society, 137(26), pp. 8380-8383. (doi:10.1021/jacs.5b04806) (PMID:26102606)

2013

Kadodwala, M. , Abdulrahman, N., Syme, C. D. , Jack, C., Barron, L. D., Karimullah, A. and Gadegaard, N. (2013) The origin of off–resonance non-linear optical activity of a gold chiral nanomaterial. Nanoscale, 5(24), pp. 12651-12657. (doi:10.1039/c3nr04746f)

Karimullah, A. S. , Cumming, D. R.S. , Riehle, M. and Gadegaard, N. (2013) Development of a conducting polymer cell impedance sensor. Sensors and Actuators B: Chemical, 176, pp. 667-674. (doi:10.1016/j.snb.2012.09.075)

This list was generated on Fri Jul 19 07:16:08 2019 BST.
Jump to: Articles
Number of items: 12.

Articles

Gilroy, C., Hashiyada, S., Endo, K., Karimullah, A. S. , Barron, L., Okamoto, H., Togawa, Y. and Kadodwala, M. (2019) Roles of superchirality and interference in chiral plasmonic biodetection. Journal of Physical Chemistry C, (doi:10.1021/acs.jpcc.9b02791) (Early Online Publication)

Kelly, C., Tullius, R., Lapthorn, A. J. , Gadegaard, N. , Cooke, G. , Barron, L. D., Karimullah, A. S. , Rotello, V. M. and Kadodwala, M. (2018) Chiral plasmonic fields probe structural order of biointerfaces. Journal of the American Chemical Society, 140(27), pp. 8509-8517. (doi:10.1021/jacs.8b03634) (PMID:29909628)

Paterson, G. W. , Karimullah, A. S. , Smith, S. G., Kadodwala, M. and MacLaren, D. A. (2018) Symmetry reduction and shape effects in concave chiral plasmonic structures. Journal of Physical Chemistry C, 122(9), pp. 5049-5056. (doi:10.1021/acs.jpcc.7b12260)

Kelly, C., Khorashad, L. K., Gadegaard, N. , Barron, L. D., Govorov, A. O., Karimullah, A. S. and Kadodwala, M. (2018) Controlling metamaterial transparency with superchiral fields. ACS Photonics, 5(2), pp. 535-543. (doi:10.1021/acsphotonics.7b01071)

Tullius, R. et al. (2017) Superchiral plasmonic phase sensitivity for fingerprinting of protein interface structure. ACS Nano, 11(12), pp. 12049-12056. (doi:10.1021/acsnano.7b04698) (PMID:29220155)

Jack, C., Karimullah, A. S. , Leyman, R., Tullius, R., Rotello, V. M., Cooke, G. , Gadegaard, N. , Barron, L. D. and Kadodwala, M. (2016) Biomacromolecular stereostructure mediates mode hybridization in chiral plasmonic nanostructures. Nano Letters, 16(9), pp. 5806-5814. (doi:10.1021/acs.nanolett.6b02549) (PMID:27547978)

Jack, C. et al. (2016) Spatial control of chemical processes on nanostructures through nano-localized water heating. Nature Communications, 7, 10946. (doi:10.1038/ncomms10946) (PMID:26961708) (PMCID:PMC4792951)

Karimullah, A. S. , Jack, C., Tullius, R., Rotello, V. M., Cooke, G. , Gadegaard, N. , Barron, L. D. and Kadodwala, M. (2015) Disposable plasmonics: plastic templated plasmonic metamaterials with tunable chirality. Advanced Materials, 27(37), pp. 5610-5616. (doi:10.1002/adma.201501816)

Paterson, G. W. , Karimullah, A. , Williamson, S. D. R., Kadodwala, M. and MacLaren, D. A. (2015) Electron energy loss spectroscopy of a chiral plasmonic structure. Journal of Physics: Conference Series, 644(1), 012005. (doi:10.1088/1742-6596/644/1/012005)

Tullius, R., Karimullah, A. S. , Rodier, M., Fitzpatrick, B., Gadegaard, N. , Barron, L. D., Rotello, V. M., Cooke, G. , Lapthorn, A. and Kadodwala, M. (2015) "Superchiral” spectroscopy: detection of protein higher order hierarchical structure with chiral plasmonic nanostructures. Journal of the American Chemical Society, 137(26), pp. 8380-8383. (doi:10.1021/jacs.5b04806) (PMID:26102606)

Kadodwala, M. , Abdulrahman, N., Syme, C. D. , Jack, C., Barron, L. D., Karimullah, A. and Gadegaard, N. (2013) The origin of off–resonance non-linear optical activity of a gold chiral nanomaterial. Nanoscale, 5(24), pp. 12651-12657. (doi:10.1039/c3nr04746f)

Karimullah, A. S. , Cumming, D. R.S. , Riehle, M. and Gadegaard, N. (2013) Development of a conducting polymer cell impedance sensor. Sensors and Actuators B: Chemical, 176, pp. 667-674. (doi:10.1016/j.snb.2012.09.075)

This list was generated on Fri Jul 19 07:16:08 2019 BST.