2024

Badve, S. V. et al. (2024) Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes: a meta-analysis of randomised controlled trials. Lancet Diabetes and Endocrinology, (doi: 10.1016/S2213-8587(24)00271-7) (PMID:39608381) (In Press)

Ho, F. K. et al. (2024) A proteomics-based approach for prediction of different cardiovascular diseases and dementia. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.070454) (PMID:39540306) (Early Online Publication)

Krentz, A., Jacob, S., Heiss, C., Sattar, N. , Lim, S., Khunti, K. and Eckel, R. H. (2024) Corrigendum to “Rising to the challenge of cardio-renal-metabolic disease in the 21st century: Translating evidence into best clinical practice to prevent and manage atherosclerosis” [Atherosclerosis, Vol 396, (September 2024), 118528]. Atherosclerosis, 398, p. 118610. (doi: 10.1016/j.atherosclerosis.2024.118610) (PMID:39341753)

Rochmawati, I. D., Deo, S. , Lees, J. S. , Mark, P. B. , Sattar, N. , Celis-Morales, C. , Pell, J. P. , Welsh, P. and Ho, F. K. (2024) Adding traditional and emerging biomarkers for risk assessment in secondary prevention: a prospective cohort study of 20,656 patients with cardiovascular disease. European Journal of Preventive Cardiology, (doi: 10.1093/eurjpc/zwae352) (PMID:39474888) (Early Online Publication)

Xiong, X. et al. (2024) Associations of serum lipid traits with fracture and osteoporosis: a prospective cohort study from the UK Biobank. Journal of Cachexia, Sarcopenia and Muscle, (doi: 10.1002/jcsm.13611) (PMID:39468953) (Early Online Publication)

Handelsman, Y. et al. (2024) DCRM 2.0: Multispecialty practice recommendations for the management of diabetes, cardiorenal, and metabolic diseases. Metabolism, 159, 155931. (doi: 10.1016/j.metabol.2024.155931) (PMID:38852020)

Liu, Q., Celis-Morales, C. , Lees, J. S. , Sattar, N. , Ho, F., Pell, J. P. , Mark, P. B. and Welsh, P. (2024) Change in physical activity and its association with decline in kidney function: A UK Biobank-based cohort study. Journal of Cachexia, Sarcopenia and Muscle, 15(5), pp. 2046-2055. (doi: 10.1002/jcsm.13551) (PMID:39155482) (PMCID:PMC11446710)

Aman, A. , Slob, E. A.W., Ward, J. , Sattar, N. and Strawbridge, R. (2024) Investigating the association of the effect of genetically proxied PCSK9i with mood disorders using cis-pQTLs: A drug-target Mendelian randomization study. PLoS ONE, 19(9), e0310396. (doi: 10.1371/journal.pone.0310396) (PMID:39325747)

Anderson, J. J., Deo, S. V. , Welsh, P. , Mackay, D. F. , Ho, F. K., Ferguson, L. D. , Celis-Morales, C. , Gill, J.R. , Pell, J. P. and Sattar, N. (2024) In which common chronic conditions can (or cannot) obesity and lifestyle factors explain higher concentrations of C-reactive protein? Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15949) (Early Online Publication)

Morrow, A. et al. (2024) Zibotentan in microvascular angina: a randomized, placebo-controlled, crossover trial. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.069901) (PMID:39217504) (Early Online Publication)

Haney, D. et al. (2024) High-sensitivity troponin T, NT-proBNP, and cognitive outcomes in SPRINT. Hypertension, 81(9), pp. 1956-1965. (doi: 10.1161/HYPERTENSIONAHA.124.22876) (PMID:38957975)

Krentz, A., Jacob, S., Heiss, C., Sattar, N. , Lim, S., Khunti, K. and Eckel, R. H. (2024) Rising to the challenge of cardio-renal-metabolic disease in the 21st century: translating evidence into best clinical practice to prevent and manage atherosclerosis. Atherosclerosis, 396, 118528. (doi: 10.1016/j.atherosclerosis.2024.118528) (PMID:39154392)

Seferović, P. M. et al. (2024) Diabetic myocardial disorder. A clinical consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases. European Journal of Heart Failure, 26(9), pp. 1893-1903. (doi: 10.1002/ejhf.3347) (PMID:38896048)

Liu, Q., Celis-Morales, C. , Sattar, N. and Welsh, P. (2024) Association of glycaemic control with intraocular pressure in a large general population: Results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865) (Early Online Publication)

Liu, Q., Celis-Morales, C. , Sattar, N. and Welsh, P. (2024) Association of glycemic control with intraocular pressure in a large general population: results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865) (PMID:39157858) (Early Online Publication)

McLaren, J., Gao, X., Ghouri, N. , Freeman, D. J. , Richardson, J. , Sattar, N. and Gill, J. M.R. (2024) Weight gain leads to greater adverse metabolic responses in South Asian compared with white European men: the GlasVEGAS study. Nature Metabolism, 6(8), pp. 1632-1645. (doi: 10.1038/s42255-024-01101-z) (PMID:39152223) (PMCID:PMC11349579) (Early Online Publication)

Petermann-Rocha, F., Zhou, Z. , Mathers, J. C., Celis-Morales, C. , Raubenheimer, D., Sattar, N. , Pell, J. P., Forrest, E. and Ho, F. K. (2024) Diet modifies the association between alcohol consumption and severe alcohol-related liver disease incidence. Nature Communications, 15(1), 6880. (doi: 10.1038/s41467-024-51314-9) (PMID:39128919) (PMCID:PMC11317484)

Carberry, J. et al. (2024) Empagliflozin to prevent progressive adverse remodelling after myocardial infarction (EMPRESS-MI): rationale and design. ESC Heart Failure, 11(4), pp. 2001-2012. (doi: 10.1002/ehf2.14830) (PMID:38715187) (PMCID:PMC11287338)

Wade, K. H., Timpson, N. J., Hamilton, F. W., Sattar, N. , Carslake, D. and Davey Smith, G. (2024) Response to “Importance of method assumptions”. Obesity, 32(8), pp. 1419-1420. (doi: 10.1002/oby.24056) (PMID:38773930) (PMCID:PMC7616298)

Churuangsuk, C., Catchpole, A., Talwar, D., Welsh, P. , Sattar, N. , Combet Aspray, E. and Lean, M. E.J. (2024) Low thiamine status in adults following low-carbohydrate / ketogenic diets: a cross-sectional comparative study of micronutrient intake and status. European Journal of Nutrition, (doi: 10.1007/s00394-024-03459-y) (PMID:38967675) (Early Online Publication)

Ahmed, A., Cule, M., Bell, J. D., Sattar, N. and Yaghootkar, H. (2024) Differing genetic variants associated with liver fat and their contrasting relationships with cardiovascular diseases and cancer. Journal of Hepatology, (doi: 10.1016/j.jhep.2024.06.030) (PMID:38960375) (Early Online Publication)

Conrad, N. et al. (2024) Temporal trends and patterns in cardiovascular disease incidence: a population-based study in 22 million individuals. British Medical Journal, 385, e078523. (doi: 10.1136/bmj-2023-078523) (PMID:38925788) (PMCID:PMC11203392)

Canning, J. et al. (2024) Methods applied to neonatal dried blood spot samples for secondary research purposes: a scoping review. Critical Reviews in Clinical Laboratory Sciences, (doi: 10.1080/10408363.2024.2360996) (PMID:38855982) (Early Online Publication)

Abraham, A. et al. (2024) Genetic evidence for distinct biological mechanisms that link adiposity to type 2 diabetes: toward precision medicine. Diabetes, 73(6), pp. 1012-1025. (doi: 10.2337/db23-1005) (PMID:38530928) (PMCID:PMC11109787)

Helmink, M. A. G. et al. (2024) Lifetime and 10-year cardiovascular risk prediction in individuals with type 1 diabetes: the LIFE-T1D model. Diabetes, Obesity and Metabolism, 26(6), pp. 2229-2238. (doi: 10.1111/dom.15531) (PMID:38456579)

Rutter, M. K. et al. (2024) Indirect effects of the COVID-19 pandemic on diagnosing, monitoring, and prescribing in people with diabetes and strategies for diabetes service recovery internationally. Diabetes Research and Clinical Practice, 212, 111693. (doi: 10.1016/j.diabres.2024.111693) (PMID:38719027)

Lawson, C. A. et al. (2024) Long COVID and cardiovascular disease: a prospective cohort study. Open Heart, 11, e002662. (doi: 10.1136/openhrt-2024-002662) (PMID:38802280) (PMCID:PMC11131117)

Sattar, N. , Lee, M. M.Y. and McGuire, D. K. (2024) What the SELECT trial of semaglutide means for clinicians. Nature Medicine, 30(7), pp. 1830-1831. (doi: 10.1038/s41591-024-03013-7) (PMID:38796654)

Sattar, N. , Neeland, I. J. and McGuire, D. K. (2024) Obesity and cardiovascular disease: a new dawn. Circulation, 149(21), pp. 1621-1623. (doi: 10.1161/CIRCULATIONAHA.123.065485) (PMID:38768272)

Hageman, S. H..J. et al. (2024) Prediction of individual lifetime cardiovascular risk and potential treatment benefit: development and recalibration of the LIFE-CVD2 model to four European risk regions. European Journal of Preventive Cardiology, (doi: 10.1093/eurjpc/zwae174) (PMID:38752762) (Early Online Publication)

Hillary, R. F. et al. (2024) Blood-based epigenome-wide analyses of chronic low-grade inflammation across diverse population cohorts. Cell Genomics, 4(5), 100544. (doi: 10.1016/j.xgen.2024.100544) (PMID:38692281) (PMCID:PMC11099341)

Cardoso, P. et al. (2024) Phenotype-based targeted treatment of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes. Diabetologia, 67(5), pp. 822-836. (doi: 10.1007/s00125-024-06099-3) (PMID:38388753) (PMCID:PMC10955037)

Carey, I. M. et al. (2024) Effects of long-term HbA1c variability on serious infection risks in patients with type 2 diabetes and the influence of age, sex and ethnicity: A cohort study of primary care data. Diabetes Research and Clinical Practice, 211, 111641. (doi: 10.1016/j.diabres.2024.111641) (PMID:38548108)

Heerspink, H. L., Tuttle, K. R., Pavo, I., Haupt, A., Yang, Z., Wiese, R. J., Hemmingway, A., Cherney, D. I., Sattar, N. and Jacob, S. (2024) Tirzepatide Reduces Albuminuria in Patients with T2D: Post-hoc Pooled Analysis of SURPASS 1-5. 58th German Diabetes Association (DDG) Diabetes Congress, Berlin, Germany, 08-11 May 2024. (doi: 10.1055/s-0044-1785384)

Karjalainen, M. K. et al. (2024) Genome-wide characterization of circulating metabolic biomarkers. Nature, 628, pp. 130-138. (doi: 10.1038/s41586-024-07148-y) (PMID:38448586) (PMCID:PMC10990933)

Sattar, N. , Presslie, C., Rutter, M. K. and McGuire,, D. K. (2024) Cardiovascular and kidney risks in individuals with type 2 diabetes: contemporary understanding with greater emphasis on excess adiposity. Diabetes Care, 47(4), pp. 531-543. (doi: 10.2337/dci23-0041) (PMID:38412040)

Berthon, W. et al. (2024) Ongoing burden and recent trends in severe hospitalised hypoglycaemia events in people with type 1 and type 2 diabetes in Scotland: A nationwide cohort study 2016-2022. Diabetes Research and Clinical Practice, 210, 111642. (doi: 10.1016/j.diabres.2024.111642) (PMID:38548109)

Ferreira, J. P. et al. (2024) Insulin‐like growth factor binding protein‐7 concentrations in chronic heart failure: results from the EMPEROR programme. European Journal of Heart Failure, 26(4), pp. 806-816. (doi: 10.1002/ejhf.3227) (PMID:38587259)

Ferreira, J. P. et al. (2024) Carbohydrate antigen 125 concentrations across the ejection fraction spectrum in chronic heart failure: the EMPEROR programme. European Journal of Heart Failure, 26(4), pp. 788-802. (doi: 10.1002/ejhf.3166) (PMID:38439582)

Lean, M. E.J. et al. (2024) 5-year follow-up of the randomised Diabetes Remission Clinical Trial (DiRECT) of continued support for weight loss maintenance in the UK: an extension study. Lancet Diabetes and Endocrinology, 12(4), pp. 233-246. (doi: 10.1016/S2213-8587(23)00385-6) (PMID:38423026)

Sattar, N. et al. (2024) Body mass index and cardiorenal outcomes in the EMPEROR-Preserved trial: principal findings and meta-analysis with the DELIVER trial. European Journal of Heart Failure, 26(4), pp. 900-909. (doi: 10.1002/ejhf.3221) (PMID:38558521)

Harrington, J., Felker, G. M., Januzzi, J. L., Lam, C. S.P., Lingvay, I., Pagidipati, N. J., Sattar, N. , Van Spall, H. G.C., Verma, S. and McGuire, D. K. (2024) Worth their weight? An update on new and emerging pharmacologic agents for obesity and their potential role for persons with cardiac conditions. Current Cardiology Reports, 26(3), pp. 61-71. (doi: 10.1007/s11886-023-02016-z) (PMID:38551786)

Suzuki, K. et al. (2024) Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature, 627(8003), pp. 347-357. (doi: 10.1038/s41586-024-07019-6) (PMID:38374256)

Haag, L. et al. (2024) Baseline characteristics in the Remote Diet Intervention to REduce long-COVID Symptoms Trial (ReDIRECT). NIHR Open Research, 4, 7. (doi: 10.3310/nihropenres.13522.1) (PMID:39145102) (PMCID:PMC11320183)

Deo, S. V. et al. (2024) Impact of residential social deprivation on prediction of heart failure in patients with type 2 diabetes: External validation and recalibration of the WATCH-DM score using real world data. Circulation: Cardiovascular Quality and Outcomes, 17(3), pp. 267-276. e010166. (doi: 10.1161/circoutcomes.123.010166) (PMID:38328913)

Ferguson, L. D. , Molenberghs, G., Verbeke, G., Rahimi, K., Rao, S., McInnes, I. B. , McMurray, J. J.V. , Sattar, N. and Conrad, N. (2024) Gout and incidence of 12 cardiovascular diseases: a case–control study including 152 663 individuals with gout and 709 981 matched controls. Lancet Rheumatology, 6(3), e156-e167. (doi: 10.1016/S2665-9913(23)00338-7)

Morrow, A. J. et al. (2024) Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization. Communications Medicine, 4, 32. (doi: 10.1038/s43856-024-00455-5) (PMID:38418616) (PMCID:PMC10901805)

Bull, C. J. et al. (2024) Impact of weight loss on cancer-related proteins in serum: results from a cluster randomised controlled trial of individuals with type 2 diabetes. EBioMedicine, 100, 104977. (doi: 10.1016/j.ebiom.2024.104977) (PMID:38290287) (PMCID:PMC10844806)

Chybowska, A. D. et al. (2024) Epigenetic contributions to clinical risk prediction of cardiovascular disease. Circulation: Genomic and Precision Medicine, 17(1), e004265. (doi: 10.1161/CIRCGEN.123.004265) (PMID:38288591)

Welsh, P. et al. (2024) Elevated lipoprotein(a) increases risk of subsequent major adverse cardiovascular events (MACE) and coronary revascularisation in incident ASCVD patients: a cohort study from the UK biobank. Atherosclerosis, 389, 117437. (doi: 10.1016/j.atherosclerosis.2023.117437) (PMID:38219651)

Farhat, G., Mellor, D. D., Sattar, N. , Harvie, M., Issa, B. and Rutter, M. K. (2024) Effectiveness of lifestyle interventions/culturally bespoke programmes in South Asian ethnic groups targeting weight loss for prevention and/or remission of type 2 diabetes: A systematic review and meta‐analysis of intervention trials. Journal of Human Nutrition and Dietetics, (doi: 10.1111/jhn.13279) (PMID:38234263) (Early Online Publication)

Aronne, L. J. et al. (2024) Continued treatment with Tirzepatide for maintenance of weight reduction in adults with obesity: The SURMOUNT-4 randomized clinical trial. JAMA: Journal of the American Medical Association, 331(1), pp. 38-48. (doi: 10.1001/jama.2023.24945) (PMID:38078870)

MacKenzie, R. M. et al. (2024) Clinical outcomes and adverse events of bariatric surgery in adults with severe obesity in Scotland: the SCOTS observational cohort study. Health Technology Assessment, 28(7), (doi: 10.3310/UNAW6331)

Corbin, L. J. et al. (2024) The metabolomic signature of weight loss and remission in the Diabetes Remission Clinical Trial (DiRECT). Diabetologia, 67(1), pp. 74-87. (doi: 10.1007/s00125-023-06019-x) (PMID:37878066) (PMCID:PMC10709482)

Lee, M. M.Y. , Kondo, T., Campbell, R. T., Petrie, M. C. , Sattar, N. , Solomon, S. D., Vaduganathan, M., Jhund, P. S. and McMurray, J. J.V. (2024) Effects of Renin-Angiotensin system blockers on outcomes from COVID-19: a systematic review and meta-analysis of randomised controlled trials. European Heart Journal: Cardiovascular Pharmacotherapy, 10(1), pp. 68-80. (doi: 10.1093/ehjcvp/pvad067) (PMID:37740450) (PMCID:PMC10766905)

Sofianopoulou, E. et al. (2024) Estimating dose—response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and revised Mendelian randomization analyses. Lancet Diabetes and Endocrinology, 12(1), E2-E11. (doi: 10.1016/S2213-8587(23)00287-5) (PMID:38048800)

2023

Lee, M. M.Y. , Lean, M. E.J. , Sattar, N. and Petrie, M. C. (2023) Appetite and its regulation: Are there palatable interventions for heart failure? Current Heart Failure Reports, 21, pp. 1-4. (doi: 10.1007/s11897-023-00637-7) (PMID:38133864) (PMCID:PMC10827951)

Donin, A., Nightingale, C. M., Sattar, N. , Fraser, W. D., Owen, C. G., Cook, D. G. and Whincup, P. H. (2023) Cross-sectional study of the associations between circulating vitamin D concentrations and insulin resistance in children aged 9-10 years of South Asian, black African Caribbean and white European origins. Journal of Epidemiology and Community Health, (doi: 10.1136/jech-2023-220626) (PMID:38123968) (Early Online Publication)

Welsh, P. et al. (2023) Multiple cardiac biomarkers to improve prediction of cardiovascular events: findings from the Generation Scotland Scottish Family Health Study. Clinical Chemistry, 70(2), pp. 403-413. (doi: 10.1093/clinchem/hvad205) (PMID:38069915)

Sattar, N. , Deanfield, J. and Delles, C. (2023) Impact of intentional weight loss in cardiometabolic disease: what we know about timing of benefits on differing outcomes? Cardiovascular Research, 119(18), e167-e171. (doi: 10.1093/cvr/cvac186) (PMID:36683167)

Berry, C. et al. (2023) Mental health symptoms and illness trajectory following COVID-19 hospitalization: A cohort study. Heart and Mind, 7(4), pp. 235-245. (doi: 10.4103/hm.HM-D-23-00037)

Goudswaard, L. J. et al. (2023) Using trials of caloric restriction and bariatric surgery to explore the effects of body mass index on the circulating proteome. Scientific Reports, 13, 21077. (doi: 10.1038/s41598-023-47030-x) (PMID:38030643) (PMCID:PMC10686974)

Ferguson, L. , McInnes, I.B., Sattar, N. and Conrad, N. (2023) Gout is Associated with Increased Cardiovascular Risk: Results from Analysis of the CPRD Dataset. ESC Congress 2023, Amsterdam, Netherlands, 25–28 August 2023. (doi: 10.1093/eurheartj/ehad655.2771)

Petermann-Rocha, F., Deo, S. , Lyall, D. , Orkaby, A. R., Quinn, T. J. , Sattar, N. , Celis-Morales, C. , Pell, J. P. and Ho, F. K. (2023) Association between the AHA Life's Essential 8 score and incident all-cause dementia: a prospective cohort study from UK Biobank. Current Problems in Cardiology, 48(11), 101934. (doi: 10.1016/j.cpcardiol.2023.101934) (PMID:37422047)

Ranglani, S., Ward, J. , Sattar, N. , Strawbridge, R. J. and Lyall, D. M. (2023) Testing for associations between HbA1c levels, polygenic risk and brain health in UK Biobank (N = 39 283). Diabetes, Obesity and Metabolism, 25(11), pp. 3136-3143. (doi: 10.1111/dom.15207) (PMID:37435691)

Sattar, N. et al. (2023) Prediction of cardiometabolic health through changes in plasma proteins with intentional weight loss in the DiRECT and DIADEM-I randomised clinical trials of type 2 diabetes remission. Diabetes Care, 46(11), pp. 1949-1957. (doi: 10.2337/dc23-0602) (PMID:37756566) (PMCID:PMC10628468)

Al Ozairi, E. et al. (2023) The effect of home-based resistance exercise training in people with type 2 diabetes: a randomized controlled trial. Diabetes/Metabolism Research and Reviews, 39(7), e3677. (doi: 10.1002/dmrr.3677) (PMID:37330638)

Boonpor, J. et al. (2023) Associations and predictive performance of eleven anthropometric measures with incident type 2 diabetes: a prospective cohort study from the UK Biobank. Obesity, 31(10), pp. 2648-2657. (doi: 10.1002/oby.23849) (PMID:37724055)

Malik, M. E. et al. (2023) Initiation of SGLT2 inhibitors and GLP-1 receptor agonists according to level of frailty in people with type 2 diabetes and cardiovascular disease in Denmark: a cross-sectional, nationwide study. Lancet Healthy Longevity, 4(10), e552-e560. (doi: 10.1016/S2666-7568(23)00164-2) (PMID:37734395)

Richardson, J. , Sattar, N. , AlOzairi, E., Dawwas, B., Raj, J., Nappoe, A., Alshammari, S. and Patil, S. (2023) Within an International Research Project, Visits to Collaborator Sites Informs Staff Training Needs, and Contributes to Successful Project Delivery. British Association for Nursing in Cardiovascular Care Conference (BANCC 2023), Coventry, UK, 15 Sept 2023.

Osadnik, K. et al. (2023) Metabolic syndrome is associated with similar long-term prognosis in non-obese and obese patients. An analysis of 45 615 patients from the nationwide LIPIDOGRAM 2004-2015 cohort studies. European Journal of Preventive Cardiology, 30(12), pp. 1195-1204. (doi: 10.1093/eurjpc/zwad101) (PMID:37039119)

Taquet, M. et al. (2023) Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization. Nature Medicine, (doi: 10.1038/s41591-023-02525-y) (PMID:37653345) (Early Online Publication)

Mangion, K. et al. (2023) Post-COVID-19 illness and associations with sex and gender. BMC Cardiovascular Disorders, 23, 389. (doi: 10.1186/s12872-023-03412-7) (PMID:37553628) (PMCID:PMC10408208)

Haag, L. et al. (2023) The remote diet intervention to reduce Long COVID symptoms trial (ReDIRECT): protocol for a randomised controlled trial to determine the effectiveness and cost-effectiveness of a remotely delivered supported weight management programme for people with Long COVID and excess weight, with personalised improvement goals. NIHR Open Research, 2, 57. (doi: 10.3310/nihropenres.13315.2) (PMID:37881302) (PMCID:PMC10593354)

Karusheva, Y. et al. (2023) Association of GDF15 levels with body mass index and endocrine status in β-thalassaemia. Clinical Endocrinology, 99(2), pp. 182-189. (doi: 10.1111/cen.14897) (PMID:36806122)

Zhou, Z., Parra-Soto, S., Boonpor, J., Petermann-Rocha, F., Welsh, P. , Mark, P. B. , Sattar, N. , Pell, J. P. , Celis-Morales, C. and Ho, F. K. (2023) Exploring the underlying mechanisms linking adiposity and cardiovascular disease: a prospective cohort study of 404,332 UK Biobank participants. Current Problems in Cardiology, 48(8), 101715. (doi: 10.1016/j.cpcardiol.2023.101715) (PMID:37004891)

Mohebi, R. et al. (2023) Insulin growth factor axis and cardio-renal risk in diabetic kidney disease: an analysis from the CREDENCE trial. Cardiovascular Diabetology, 22, 176. (doi: 10.1186/s12933-023-01916-2) (PMID:37438734) (PMCID:PMC10339517)

Docherty, K. F. et al. (2023) Association of carbohydrate antigen 125 on the response to dapagliflozin in patients with heart failure. Journal of the American College of Cardiology, 82(2), pp. 142-157. (doi: 10.1016/j.jacc.2023.05.011) (PMID:37407113)

Boonpor, J. et al. (2023) Association between walking pace and incident type 2 diabetes by adiposity levels – a prospective cohort study from the UK Biobank. Diabetes, Obesity and Metabolism, 25(7), pp. 1900-1910. (doi: 10.1111/dom.15053) (PMID:36951683)

Lee, M. M.Y. and Sattar, N. (2023) A review of current key guidelines for managing high risk patients with diabetes and heart failure and future prospects. Diabetes, Obesity and Metabolism, 25(S3), pp. 33-47. (doi: 10.1111/dom.15085) (PMID:37041663)

Soltanisarvestani, M., Lynskey, N., Gray, S. , Gill, J. M.R. , Pell, J. P. , Sattar, N. , Welsh, P. , Ho, F. K., Celis-Morales, C. and Petermann-Rocha, F. (2023) Associations of grip strength and walking pace with mortality in stroke survivors: a prospective study from UK Biobank. Scandinavian Journal of Medicine and Science in Sports, 33(7), pp. 1190-1200. (doi: 10.1111/sms.14352) (PMID:36932055)

Verma, S. et al. (2023) Presence of peripheral artery disease is associated with increased risk of heart failure events: insights from EMPEROR-Pooled. Arteriosclerosis, Thrombosis, and Vascular Biology, 43(7), pp. 1334-1337. (doi: 10.1161/ATVBAHA.123.319156) (PMID:37199158) (PMCID:PMC10281175)

Sattar, N. et al. (2023) Years of cardiovascular complications and risk factors in patients with type 2 diabetes: a nationwide Swedish cohort study. Circulation, 147(25), pp. 1872-1886. (doi: 10.1161/CIRCULATIONAHA.122.063374) (PMID:37154040)

Conrad, N. et al. (2023) Incidence, prevalence, and co-occurrence of autoimmune disorders over time and by age, sex, and socioeconomic status: a population-based cohort study of 22 million individuals in the UK. Lancet, 401(10391), pp. 1878-1890. (doi: 10.1016/S0140-6736(23)00457-9) (PMID:37156255)

Schreiner, A. D. and Sattar, N. (2023) Identifying patients with nonalcoholic fatty liver disease in primary care: how and for what benefit? Journal of Clinical Medicine, 12(12), 4001. (doi: 10.3390/jcm12124001) (PMID:37373694) (PMCID:PMC10298910)

Yeoh, S. E. et al. (2023) Endothelin-1, outcomes in patients with heart failure and reduced ejection fraction, and effects of dapagliflozin: findings from DAPA-HF. Circulation, 147(22), pp. 1670-1683. (doi: 10.1161/CIRCULATIONAHA.122.063327) (PMID:37039015) (PMCID:PMC10212584)

Boonpor, J. et al. (2023) Dose–response relationship between device-measured physical activity and incident type 2 diabetes: findings from the UK Biobank prospective cohort study. BMC Medicine, 21, 191. (doi: 10.1186/s12916-023-02851-5) (PMID:37226202) (PMCID:PMC10210409)

Aletaha, D. et al. (2023) Consensus statement on blocking interleukin-6 receptor and interleukin-6 in inflammatory conditions: an update. Annals of the Rheumatic Diseases, 82(6), pp. 773-787. (doi: 10.1136/ard-2022-222784) (PMID:35953263)

Girerd, N. et al. (2023) Protein biomarkers of new-onset heart failure: insights from the Heart Omics and Ageing cohort, the Atherosclerosis Risk in Communities Study, and the Framingham Heart Study. Circulation: Heart Failure, 16(5), pp. 426-441. (doi: 10.1161/CIRCHEARTFAILURE.122.009694) (PMID:37192292) (PMCID:PMC10179982)

Holman, N. , Barron, E., Young, B., Gregg, E. W., Khunti, K., Valabhji, J. and Sattar, N. (2023) Comparative incidence of diabetes following hospital admission for COVID-19 and pneumonia: a cohort study. Diabetes Care, 46(5), pp. 938-943. (doi: 10.2337/dc22-0670) (PMID:36657086)

Sattar, N. (2023) Statins and diabetes: what are the connections? Best Practice and Research: Clinical Endocrinology and Metabolism, 37(3), 101749. (doi: 10.1016/j.beem.2023.101749) (PMID:36858834)

Wang, H. et al. (2023) Cardiovascular safety in type 2 diabetes with sulfonylureas as second-line drugs: a nation-wide population-based comparative safety study. Diabetes Care, 46(5), pp. 967-977. (doi: 10.2337/dc22-1238) (PMID:36944118) (PMCID:PMC10154665)

Butt, J. H. et al. (2023) Anthropometric measures and adverse outcomes in heart failure with reduced ejection fraction: revisiting the obesity paradox. European Heart Journal, 44(13), pp. 1136-1153. (doi: 10.1093/eurheartj/ehad083) (PMID:36944496) (PMCID:PMC10111968)

Al-Sawaf, O. et al. (2023) Body composition and lung cancer-associated cachexia in TRACERx. Nature Medicine, 29(4), pp. 846-858. (doi: 10.1038/s41591-023-02232-8) (PMID:37045997) (PMCID:PMC7614477)

Conrad, N., McInnes, I. B. , Mcmurray, J. J.V. and Sattar, N. (2023) Patients with a range of rheumatic diseases are at increased risk of cardiovascular disorders towards a re-evaluation of the European League against Rheumatism (EULAR)'s recommendations for cardiovascular risk management? Annals of the Rheumatic Diseases, 82(4), pp. 457-459. (doi: 10.1136/ard-2022-223315) (PMID:36442979)

Petermann-Rocha, F., Deo, S. , Celis-Morales, C. , Ho, F. K., Bahuguna, P. , McAllister, D. , Sattar, N. and Pell, J. P. (2023) An opportunity for prevention: associations between the Life's Essential 8 score and cardiovascular incidence using prospective data from UK Biobank. Current Problems in Cardiology, 48(4), 101540. (doi: 10.1016/j.cpcardiol.2022.101540) (PMID:36528209)

Gerstein, H. C. et al. (2023) Exploring the relationship between efpeglenatide dose and cardiovascular outcomes in type 2 diabetes: insights from the AMPLITUDE-O trial. Circulation, 147(3), pp. 1004-1013. (doi: 10.1161/CIRCULATIONAHA.122.063716) (PMID:36802715)

Tabák, A. G., Sattar, N. and Kivimäki, M. (2023) Response by Tabák et al to letters regarding article, “Risk of macrovascular and microvascular disease in diabetes diagnosed using oral glucose tolerance test with and without confirmation by hemoglobin A1c: the Whitehall II cohort study”. Circulation, 147(12), pp. 988-989. (doi: 10.1161/CIRCULATIONAHA.123.063545) (PMID:36944036)

Adamson, C. et al. (2023) IGFBP-7 and outcomes in heart failure with reduced ejection fraction: findings from DAPA-HF. JACC: Heart Failure, 11(3), pp. 291-304. (doi: 10.1016/j.jchf.2022.09.004) (PMID:36592046)

Cassidy, S. et al. (2023) Physical activity, inactivity and sleep during the Diabetes Remission Clinical Trial (DiRECT). Diabetic Medicine, 40(3), e15010. (doi: 10.1111/dme.15010) (PMID:36398460)

Holman, N. , Khunti, K., Wild, S. H., Sattar, N. , Knighton, P., Young, B., Gregg, E. W., Bakhai, C. and Valabhji, J. (2023) Care processes in people in remission from type 2 diabetes: a cohort study using the National Diabetes Audit. Diabetic Medicine, 40(3), e15016. (doi: 10.1111/dme.15016) (PMID:36440921) (PMCID:PMC10108144)

Chu, W., Lynskey, N., Iain-Ross, J., Pell, J. P. , Sattar, N. , Ho, F. K., Welsh, P. , Celis-Morales, C. and Petermann-Rocha, F. (2023) Identifying the biomarker profile of pre-frail and frail people: a cross-sectional analysis from UK Biobank. International Journal of Environmental Research and Public Health, 20(3), 2421. (doi: 10.3390/ijerph20032421) (PMID:36767787) (PMCID:PMC9915970)

Chua, S. Y.L. et al. (2023) Associations between HbA1c across the normal range, diagnosed, and undiagnosed diabetes and retinal layer thickness in UK Biobank cohort. Translational Vision Science and Technology, 12(2), 25. (doi: 10.1167/tvst.12.2.25) (PMID:36795065) (PMCID:PMC9940769)

Deo, S. et al. (2023) Lipid-lowering in ‘very high risk’ patients undergoing coronary artery bypass surgery and its projected reduction in risk for recurrent vascular events: A Monte Carlo stepwise simulation approach. Journal of Cardiovascular Pharmacology, 81(2), pp. 120-128. (doi: 10.1097/FJC.0000000000001374) (PMID:36315474)

Malik, M. E. et al. (2023) Clinical cardiovascular phenotypes and the pattern of future events in patients with type 2 diabetes. Clinical Research in Cardiology, 112(2), pp. 215-226. (doi: 10.1007/s00392-022-02016-z) (PMID:35396632)

Sattar, N. , Welsh, P. , Leslie, W. S., Thom, G. , McCombie, L., Brosnahan, N. , Richardson, J. , Gill, J. M. R. , Crawford, L. and Lean, M. E. J. (2023) Dietary weight-management for type 2 diabetes remissions in South Asians: the South Asian diabetes remission randomised trial for proof-of-concept and feasibility (STANDby). Lancet Regional Health – Southeast Asia, 9, 100111. (doi: 10.1016/j.lansea.2022.100111) (PMID:36777452) (PMCID:PMC9904218)

Shields, B. M., Angwin, C. D., Shepherd, M. H., Britten, N., Jones, A. G., Sattar, N. , Holman, R., Pearson, E. R. and Hattersley, A. T. (2023) Patient preference for second- and third-line therapies in type 2 diabetes: a prespecified secondary endpoint of the TriMaster study. Nature Medicine, 29(2), pp. 384-391. (doi: 10.1038/s41591-022-02121-6) (PMID:36477734) (PMCID:PMC7614215)

Ward, J. et al. (2023) Testing for association between exonic glucagon-like peptide 1 receptor mutation with physical and brain health traits in UK Biobank. Diabetes, Obesity and Metabolism, 25(2), pp. 623-627. (doi: 10.1111/dom.14879) (PMID:36181450)

Rawshani, A. et al. (2023) Cardiac arrhythmias and conduction abnormalities in patients with type 2 diabetes. Scientific Reports, 13, 1192. (doi: 10.1038/s41598-023-27941-5) (PMID:36681691) (PMCID:PMC9867726)

Verma, S. et al. (2023) Empagliflozin in black versus white patients with heart failure: analysis of EMPEROR-pooled. Circulation, 147(1), pp. 101-104. (doi: 10.1161/circulationaha.122.062644) (PMID:36342827)

Anker, S. D. et al. (2023) Weight change and clinical outcomes in heart failure with reduced ejection fraction: insights from EMPEROR-Reduced. European Journal of Heart Failure, 25(1), pp. 117-127. (doi: 10.1002/ejhf.2728) (PMID:36325584)

Bleken Østergaard, H. et al. (2023) Estimating individual lifetime risk of incident cardiovascular events in adults with type 2 diabetes: an update and geographical calibration of the DIAbetes Lifetime perspective model (DIAL2). European Journal of Preventive Cardiology, 30(1), pp. 61-69. (doi: 10.1093/eurjpc/zwac232) (PMID:36208182)

Hastie, C. E. , Foster, H. M.E. , Jani, B. D. , O'Donnell, C. A. , Ho, F. K., Pell, J. P. , Sattar, N. , Katikireddi, S. V. , Mair, F. S. and Nicholl, B. I. (2023) Chronic pain and COVID-19 hospitalisation and mortality: a UK Biobank cohort study. Pain, 164(1), pp. 84-90. (doi: 10.1097/j.pain.0000000000002663) (PMID:35452027) (PMCID:PMC9756431)

Iliodromiti, S. et al. (2023) Liver, visceral and subcutaneous fat in men and women of South Asian and white European descent: a systematic review and meta-analysis of new and published data. Diabetologia, 66(1), pp. 44-56. (doi: 10.1007/s00125-022-05803-5) (PMID:36224274) (PMCID:PMC9729139)

Sattar, N. , McMurray, J. J. V. , McInnes, I. B. , Aroda, V. R. and Lean, M. E. J. (2023) Treating chronic diseases without tackling excess adiposity promotes multimorbidity. Lancet Diabetes and Endocrinology, 11(1), pp. 58-62. (doi: 10.1016/S2213-8587(22)00317-5) (PMID:36460014)

Sykes, R. et al. (2023) Adjudicated myocarditis and multisystem illness trajectory in healthcare workers post-COVID-19. Open Heart, 10(1), e002192. (doi: 10.1136/openhrt-2022-002192) (PMID:36822817) (PMCID:PMC9950584)

Welsh, P. and Sattar, N. (2023) To apoB or not to apoB: new arguments, but basis for widespread implementation remains elusive. Clinical Chemistry, 69(1), pp. 3-5. (doi: 10.1093/clinchem/hvac183) (PMID:36427190)

Zonneveld, M. H., Noordam, R., Sabayan, B., Stott, D. J. , Mooijaart, S. P., Blauw, G. J., Jukema, J. W., Sattar, N. and Trompet, S. (2023) Weight loss, visit-to-visit body weight variability and cognitive function in older individuals. Age and Ageing, 52(1), afac312. (doi: 10.1093/ageing/afac312) (PMID:36626325)

Lean, M. E.J. , Taylor, R. and Sattar, N. (2023) Determination of autoantibodies in type 2 diabetes: one simple way to improve classification. Reply by Lean et al to Ludvigsson J [letter]. Diabetologia, 66, pp. 958-959. (doi: 10.1007/s00125-022-05863-7) (PMID:36690837) (PMCID:PMC9870768)

2022

White, S. L., Pasupathy, D., Begum, S., Sattar, N. , Nelson, S. M. , Seed, P. and Poston, L. (2022) Gestational diabetes in women with obesity; an analysis of clinical history and simple clinical/anthropometric measures. PLoS ONE, 17(12), e0279642. (doi: 10.1371/journal.pone.0279642) (PMID:36584215) (PMCID:PMC9803279)

Aman, A. , Slob, E. A.W., Ward, J. , Cullen, B. , Graham, N., Lyall, D. M. , Sattar, N. and Strawbridge, R. J. (2022) Investigating the potential impact of PCSK9-inhibitors on mood disorders using eQTL-based Mendelian randomization. PLoS ONE, 17(12), e0279381. (doi: 10.1371/journal.pone.0279381) (PMID:36580462) (PMCID:PMC9799310)

Zannad, F. et al. (2022) Effect of empagliflozin on circulating proteomics in heart failure: mechanistic insights from the EMPEROR program. European Heart Journal, 43(48), pp. 4991-5002. (doi: 10.1093/eurheartj/ehac495) (PMID:36017745)

Marx, N., Husain, M., Lehrke, M., Verma, S. and Sattar, N. (2022) GLP-1 receptor agonists for the reduction of atherosclerotic cardiovascular risk in patients with type 2 diabetes. Circulation, 146(24), pp. 1882-1894. (doi: 10.1161/CIRCULATIONAHA.122.059595) (PMID:36508493)

Ahmed, A., Sattar, N. and Yaghootkar, H. (2022) Advancing a causal role of type 2 diabetes and its components in developing macro‐ and microvascular complications via genetic studies. Diabetic Medicine, 39(12), e14982. (doi: 10.1111/dme.14982) (PMID:36256488)

Dennis, J. M. et al. (2022) Development of a treatment selection algorithm for SGLT2 and DPP-4 inhibitor therapies in people with type 2 diabetes: a retrospective cohort study. Lancet Digital Health, 4(12), e873-e883. (doi: 10.1016/S2589-7500(22)00174-1) (PMID:36427949)

Deo, S. V. , McAllister, D. A. , Al-Kindi, S., Elgudin, Y., Chu, D., Pell, J. and Sattar, N. (2022) Trends in prescriptions of cardioprotective diabetic agents after coronary artery bypass grafting among U.S. veterans. Diabetes Care, 45(12), pp. 3054-3057. (doi: 10.2337/dc22-0570) (PMID:36256925)

Gerstein, H. C. and Sattar, N. (2022) Reduction in heart failure outcomes with SGLT2 inhibitors irrespective of glycaemic status. Lancet Diabetes and Endocrinology, 10(12), pp. 831-832. (doi: 10.1016/S2213-8587(22)00313-8) (PMID:36372068)

Østergaard, H. B. et al. (2022) Development and validation of a lifetime risk model for kidney failure and treatment benefit in type 2 diabetes: 10-year and lifetime risk prediction models. Clinical Journal of the American Society of Nephrology, 17(12), pp. 1783-1791. (doi: 10.2215/CJN.05020422) (PMID:36332974)

Rosengren, A. et al. (2022) COVID-19 in people aged 18-64 in Sweden in the first year of the pandemic: Key factors for severe disease and death. Global Epidemiology, 4, 100095. (doi: 10.1016/j.gloepi.2022.100095) (PMID:36447481) (PMCID:PMC9683858)

Sharma, A., Lee-Ødegård, S., Qvigstad, E., Sommer, C., Sattar, N. , Gill, J. M.R. , Gulseth, H. L., Sollid, S. T., Nermoen, I. and Birkeland, K. I. (2022) Beta cell function, hepatic insulin clearance, and insulin sensitivity in South Asian and Nordic women after gestational diabetes mellitus. Diabetes, 71(12), pp. 2530-2538. (doi: 10.2337/db22-0622) (PMID:36112815)

Wang, J. et al. (2022) Association of maternal lipid levels with birth weight and cord blood insulin: a Bayesian network analysis. BMJ Open, 12(12), e064122. (doi: 10.1136/bmjopen-2022-064122) (PMID:36581404) (PMCID:PMC9806023)

Kilpi, F., Soares, A. G., Clayton, G. L., Fraser, A., Welsh, P. , Sattar, N. , Nelson, S. M. , Tilling, K. and Lawlor, D. A. (2022) Changes in women’s physical function in mid-life by reproductive age and hormones: a longitudinal study. BMC Women's Health, 22, 473. (doi: 10.1186/s12905-022-02070-9) (PMID:36434722) (PMCID:PMC9700972)

Mark, P. B. and Sattar, N. (2022) Implementation, not hesitation, for SGLT2 inhibition as foundational therapy for chronic kidney disease. Lancet, 400(10365), pp. 1745-1747. (doi: 10.1016/S0140-6736(22)02164-X) (PMID:36351457)

Paterson, C., Hinterberg, M. A., Morrow, A. J. , Sykes, R. , Mangion, K., Welsh, P. , McConnachie, A. , Sattar, N. , Berry, C. and Williams, S. A. (2022) Utility of a Proteomic Surrogate for Cardiovascular Outcomes to Predict and Monitor COVID-19 Induced Myocarditis. American Heart Association's 2022 Scientific Sessions and the American Heart Association's 2022 Resuscitation Science Symposium, Chicago, Illinois, USA, 04-07 Nov 2022. (doi: 10.1161/circ.146.suppl_1.12132)

Karusheva, Y. et al. (2022) Common H202D variant in GDF-15 does not affect its bioactivity but can significantly interfere with measurement of its circulating levels. Journal of Applied Laboratory Medicine, 7(6), pp. 1388-1400. (doi: 10.1093/jalm/jfac055) (PMID:35796717)

Lopez-Jimenez, F. et al. (2022) Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity Federation. European Journal of Preventive Cardiology, 29(17), pp. 2218-2237. (doi: 10.1093/eurjpc/zwac187) (PMID:36007112)

Yengo, L. et al. (2022) A saturated map of common genetic variants associated with human height. Nature Communications, 610, pp. 704-712. (doi: 10.1038/s41586-022-05275-y) (PMID:36224396) (PMCID:PMC9605867)

Butterly, E. et al. (2022) Calibrating a network meta-analysis of diabetes trials of sodium glucose cotransporter 2 inhibitors, glucagon-like peptide-1 receptor analogues and dipeptidyl peptidase-4 inhibitors to a representative routine population: a systematic review protocol. BMJ Open, 12(10), e066491. (doi: 10.1136/bmjopen-2022-066491) (PMID:36302574) (PMCID:PMC9621152)

McGurnaghan, S. J. et al. (2022) Cohort profile: the Scottish Diabetes Research Network national diabetes cohort – a population-based cohort of people with diabetes in Scotland. BMJ Open, 12(10), e063046. (doi: 10.1136/bmjopen-2022-063046) (PMID:36223968) (PMCID:PMC9562713)

McMurray, J. J. V. and Sattar, N. (2022) Heart failure: now centre-stage in diabetes. Lancet Diabetes and Endocrinology, 10(10), pp. 689-691. (doi: 10.1016/S2213-8587(22)00249-2) (PMID:36057271)

Rosengren, A. et al. (2022) Severe COVID‐19 in people 55 and older during the first year of the pandemic in Sweden. Journal of Internal Medicine, 292(4), pp. 641-653. (doi: 10.1111/joim.13522) (PMID:35612518) (PMCID:PMC9348046)

Welsh, P. et al. (2022) Reference ranges for NT-proBNP (N-terminal pro-B-type natriuretic peptide) and risk factors for higher NT-proBNP concentrations in a large general population cohort. Circulation: Heart Failure, 15(10), pp. 957-967. (doi: 10.1161/CIRCHEARTFAILURE.121.009427) (PMID:36098049) (PMCID:PMC9561238)

Docherty, K. F. et al. (2022) Iron deficiency in heart failure and effect of dapagliflozin: findings from DAPA-HF. Circulation, 146(13), pp. 980-994. (doi: 10.1161/CIRCULATIONAHA.122.060511) (PMID:35971840) (PMCID:PMC9508991)

Tabák, A. G., Brunner, E. J., Lindbohm, J. V., Singh-Manoux, A., Shipley, M. J., Sattar, N. and Kivimäki, M. (2022) Risk of macrovascular and microvascular disease in diabetes diagnosed using oral glucose tolerance test with and without confirmation by hemoglobin A1c: the Whitehall II cohort study. Circulation, 146(13), pp. 995-1005. (doi: 10.1161/CIRCULATIONAHA.122.059430) (PMID:36004644) (PMCID:PMC9508989)

Sharma, A., Nermoen, I., Qvigstad, E., Tran, A. T., Sommer, C., Sattar, N. , Gill, J. M.R. , Gulseth, H. L., Sollid, S. T. and Birkeland, K. I. (2022) High prevalence and significant ethnic differences in actionable HbA 1C after gestational diabetes mellitus in women living in Norway. BMC Medicine, 20, 318. (doi: 10.1186/s12916-022-02515-w) (PMID:36138475) (PMCID:PMC9502889)

Ho, F. K. et al. (2022) Association between device-measured physical activity and incident heart failure: a prospective cohort study of 94 739 UK Biobank participants. Circulation, 146(12), pp. 883-891. (doi: 10.1161/CIRCULATIONAHA.122.059663) (PMID:36036153)

Toth, P. P., Bray, S., Villa, G., Palagashvili, T., Sattar, N. , Stroes, E. S. G. and Worth, G. M. (2022) Network meta‐analysis of randomized trials evaluating the comparative efficacy of lipid‐lowering therapies added to maximally tolerated statins for the reduction of low‐density lipoprotein cholesterol. Journal of the American Heart Association, 11(18), e025551. (doi: 10.1161/JAHA.122.025551) (PMID:36073669) (PMCID:PMC9683660)

Madjedi, K. M. et al. (2022) The association between serum lipids and intraocular pressure in two large UK cohorts. Ophthalmology, 129(9), pp. 986-996. (doi: 10.1016/j.ophtha.2022.04.023) (PMID:35500606)

Nazarzadeh, M. et al. (2022) Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis. Lancet Diabetes and Endocrinology, 10(9), pp. 645-654. (doi: 10.1016/S2213-8587(22)00172-3) (PMID:35878651) (PMCID:PMC9622419)

Clayton, G. L., Soares, A. G., Kilpi, F., Fraser, A., Welsh, P. , Sattar, N. , Nelson, S. M. , Tilling, K. and Lawlor, D. A. (2022) Cardiovascular health in the menopause transition: a longitudinal study of up to 3892 women with up to four repeated measures of risk factors. BMC Medicine, 20, 299. (doi: 10.1186/s12916-022-02454-6) (PMID:35974322) (PMCID:PMC9382827)

Sattar, N. , Anker, S. D., Butler, J. and Verma, S. (2022) Obesity, heart failure, and SGLT2 inhibition: DECLARE-TIMI 58 provides insights. European Heart Journal, 43(31), pp. 2968-2970. (doi: 10.1093/eurheartj/ehab709) (PMID:34618015)

Höhn, A. et al. (2022) Large socioeconomic gap in period life expectancy and life years spent with complications of diabetes in the Scottish population with type 1 diabetes, 2013–2018. PLoS ONE, 17(8), e0271110. (doi: 10.1371/journal.pone.0271110) (PMID:35951518) (PMCID:PMC9371295)

Deo, S. V. , Marsia, S., McAllister, D. A. , Elgudin, Y., Sattar, N. and Pell, J. P. (2022) The time-varying cardiovascular benefits of glucagon like peptide-1 receptor agonist therapy in patients with type 2 diabetes mellitus: evidence from large multinational trials. Diabetes, Obesity and Metabolism, 24(8), pp. 1607-1616. (doi: 10.1111/dom.14738) (PMID:35491516)

Valabhji, J., Barron, E., Gorton, T., Bakhai, C., Kar, P., Young, B., Khunti, K., Holman, N. , Sattar, N. and Wareham, N. J. (2022) Associations between reductions in routine care delivery and non-COVID-19-related mortality in people with diabetes in England during the COVID-19 pandemic: a population-based parallel cohort study. Lancet Diabetes and Endocrinology, 10(8), pp. 561-570. (doi: 10.1016/S2213-8587(22)00131-0) (PMID:35636440) (PMCID:PMC9141683)

Lee, M. M.Y. et al. (2022) Effect of empagliflozin on kidney biochemical and imaging outcomes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF). Circulation, 146(4), pp. 364-367. (doi: 10.1161/CIRCULATIONAHA.122.059851) (PMID:35877829)

Kimenai, D. M. et al. (2022) Socioeconomic deprivation: an important, largely unrecognized risk factor in primary prevention of cardiovascular disease. Circulation, 146(3), pp. 240-248. (doi: 10.1161/CIRCULATIONAHA.122.060042) (PMID:35748241)

Sattar, N. , McGuire, D. K. and Gill, J. M.R. (2022) High circulating triglycerides are most commonly a marker of ectopic fat accumulation: connecting the clues to advance lifestyle interventions. Circulation, 146(2), pp. 77-79. (doi: 10.1161/CIRCULATIONAHA.122.060411) (PMID:35858157)

Colaço, K. et al. (2022) Association of cardiac biomarkers with cardiovascular outcomes in patients with psoriatic arthritis and psoriasis: a longitudinal cohort study. Arthritis and Rheumatology, 74(7), pp. 1184-1192. (doi: 10.1002/art.42079) (PMID:35261189)

Thygesen, J. H. et al. (2022) COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records. Lancet Digital Health, 7(4), e542-e557. (doi: 10.1016/S2589-7500(22)00091-7) (PMID:35690576) (PMCID:PMC9179175)

Davis, T. M. E., Giczewska, A., Lokhnygina, Y., Mentz, R. J., Sattar, N. and Holman, R. R. (2022) Effect of race on cardiometabolic responses to once-weekly exenatide: insights from the Exenatide Study of Cardiovascular Event Lowering (EXSCEL). Cardiovascular Diabetology, 21, 116. (doi: 10.1186/s12933-022-01555-z) (PMID:35761271) (PMCID:PMC9238154)

Du Puy, R. S. et al. (2022) No effect of levothyroxine on hemoglobin in older adults with subclinical hypothyroidism: pooled results from 2 randomized controlled trials. Journal of Clinical Endocrinology and Metabolism, 107(6), e2339-e2347. (doi: 10.1210/clinem/dgac106) (PMID:35218666)

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Ho, F. K. et al. (2022) Association of gamma-glutamyltransferase levels with total mortality, liver-related, and cardiovascular outcomes: a prospective cohort study in the UK Biobank. EClinicalMedicine, 48, 101435. (doi: 10.1016/j.eclinm.2022.101435) (PMID:35706481) (PMCID:PMC9112033)

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2021

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Thom, G. et al. (2021) Predictors of type 2 diabetes in the Diabetes Remission Clinical Trial (DiRECT). Diabetic Medicine, 38(8), e14395. (doi: 10.1111/dme.14395) (PMID:32870520)

Lee, M. M.Y. , McMurray, J. J.V. , Jhund, P. S. , Petrie, M. C. and Sattar, N. (2021) Response by Lee et al to letter regarding article, "Effect of Empagliflozin on Left Ventricular Volumes in Patients With Type 2 Diabetes, or Prediabetes, and Heart Failure With Reduced Ejection Fraction (SUGAR-DM-HF)". Circulation, 144(3), e40. (doi: 10.1161/CIRCULATIONAHA.121.055067) (PMID:34279995)

Sattar, N. and McGuire, D. K. (2021) Prevention of CV outcomes in antihyperglycemic drug-naïve patients with type 2 diabetes with, or at elevated risk of, atherosclerotic cardiovascular disease: to start or not to start with metformin. European Heart Journal, 42(26), pp. 2574-2576. (doi: 10.1093/eurheartj/ehaa879) (PMID:33200189)

Krzemień, P. et al. (2021) Serum antinuclear autoantibodies are associated with measures of oxidative stress and lifestyle factors - analysis of LIPIDOGRAM2015 and LIPIDOGEN2015 studies. Archives of Medical Science, 19(5), (doi: 10.5114/aoms/139313)

Gerstein, H. C. et al. (2021) Cardiovascular and renal outcomes with efpeglenatide in type 2 diabetes. New England Journal of Medicine, (doi: 10.1056/NEJMoa2108269) (PMID:34215025)

Brosnahan, N. , Leslie, W., McCombie, L., Barnes, A., Thom, G. , McConnachie, A. , Messow, C. M. , Sattar, N. , Taylor, R. and Lean, M. E.J. (2021) Brief formula low‐energy‐diet for relapse management during weight loss maintenance in the Diabetes Remission Clinical Trial (DiRECT). Journal of Human Nutrition and Dietetics, 34(3), pp. 472-479. (doi: 10.1111/jhn.12839) (PMID:33406285)

Chen, J. et al. (2021) The trans-ancestral genomic architecture of glycemic traits. Nature Genetics, 53(6), pp. 840-860. (doi: 10.1038/s41588-021-00852-9) (PMID:34059833) (PMCID:PMC7610958)

Eastwood, S. V., Mathur, R., Sattar, N. , Smeeth, L., Bhaskaran, K. and Chaturvedi, N. (2021) Ethnic differences in guideline-indicated statin initiation for people with type 2 diabetes in UK primary care, 2006–2019: a cohort study. PLoS Medicine, 18(6), e1003672. (doi: 10.1371/journal.pmed.1003672) (PMID:34185782) (PMCID:PMC8241069)

Höhn, A. et al. (2021) The association of polypharmacy and high-risk drug classes with adverse health outcomes in the Scottish population with type 1 diabetes. Diabetologia, 64, pp. 1309-1319. (doi: 10.1007/s00125-021-05394-7) (PMID:33608768) (PMCID:PMC8099818)

Sattar, N. and Januzzi, J. L. (2021) Can biomarkers help find the ‘sweet spot’ for treating patients with diabetes? European Journal of Heart Failure, 23(6), pp. 1037-1039. (doi: 10.1002/ejhf.2175) (PMID:33786946)

Timmons, J. G. et al. (2021) Metformin and carotid intima-media thickness in never-smokers with type 1 diabetes: the REMOVAL trial. Diabetes, Obesity and Metabolism, 23(6), pp. 1371-1378. (doi: 10.1111/dom.14350) (PMID:33591613)

Schunk, S. J. et al. (2021) Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. European Heart Journal, 42(18), pp. 1742-1756. (doi: 10.1093/eurheartj/ehab107) (PMID:33748830)

Lee, M. M.Y. , Ghouri, N. , McGuire, D. K., Rutter, M. K. and Sattar, N. (2021) Meta-analyses of results from randomized outcome trials comparing cardiovascular effects of SGLT2i and GLP-1RA in Asian vs. White patients with and without type 2 diabetes. Diabetes Care, 44(5), pp. 1236-1241. (doi: 10.2337/dc20-3007) (PMID:33707305)

Khunti, K. et al. (2021) Prescription of glucose-lowering therapies and risk of COVID-19 mortality in people with type 2 diabetes: a nationwide observational study in England. Lancet Diabetes and Endocrinology, 9(5), pp. 293-303. (doi: 10.1016/S2213-8587(21)00050-4) (PMID:33798464) (PMCID:PMC8009618)

Mutambudzi, M. et al. (2021) Occupation and risk of severe COVID-19: prospective cohort study of 120 075 UK Biobank participants. Occupational and Environmental Medicine, 78(5), pp. 307-314. (doi: 10.1136/oemed-2020-106731) (PMID:33298533)

Rawshani, A. et al. (2021) Severe COVID-19 in people with type 1 and type 2 diabetes in Sweden: a nationwide retrospective cohort study. Lancet Regional Health - Europe, 4, 100105. (doi: 10.1016/j.lanepe.2021.100105) (PMID:33969336) (PMCID:PMC8086507)

Sattar, N. and Forouhi, N. G. (2021) More evidence for 5-a-day for fruit and vegetables and a greater need for translating dietary research evidence to practice. Circulation, 143(17), pp. 1655-1658. (doi: 10.1161/CIRCULATIONAHA.121.053293) (PMID:33900834)

Höskuldsdóttir, G., Sattar, N. , Miftaraj, M., Näslund, I., Ottosson, J., Franzén, S., Svensson, A.-M. and Eliasson, B. (2021) Potential effects of bariatric surgery on the incidence of heart failure and atrial fibrillation in patients with type 2 diabetes mellitus and obesity and on mortality in patients with preexisting heart failure: a nationwide, matched, observational cohort study. Journal of the American Heart Association, 10(7), e019323. (doi: 10.1161/JAHA.120.019323) (PMID:33754795) (PMCID:PMC8174344)

Ferguson, L. D. , Linge, J., Leinhard, O. D., Woodward, R., Hall Barrientos, P., Roditi, G., Radjenovic, A. , McInnes, I. B. , Siebert, S. and Sattar, N. (2021) Psoriatic arthritis is associated with adverse body composition predictive of greater coronary heart disease and type 2 diabetes propensity – a cross-sectional study. Rheumatology, 60(4), pp. 1858-1862. (doi: 10.1093/rheumatology/keaa604) (PMID:33147607)

Packer, M. et al. (2021) Empagliflozin in patients with heart failure, reduced ejection fraction, and volume overload EMPEROR-Reduced trial. Journal of the American College of Cardiology, 77(11), pp. 1381-1392. (doi: 10.1016/j.jacc.2021.01.033) (PMID:33736819)

Petermann-Rocha, F., Parra-Soto, S., Gray, S. , Anderson, J. , Welsh, P. , Gill, J. , Sattar, N. , Ho, F. K., Celis-Morales, C. and Pell, J. P. (2021) Vegetarians, fish, poultry and meat-eaters: who has higher risk of CVD incidence and mortality? A prospective study from UK Biobank. European Heart Journal, 42(12), pp. 1136-1143. (doi: 10.1093/eurheartj/ehaa939) (PMID:33313747)

Bos, M. M. et al. (2021) Investigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses. BMC Medicine, 19(1), p. 69. (doi: 10.1186/s12916-021-01939-0) (PMID:33731105) (PMCID:PMC7971964)

Ferguson, L. D. , Sattar, N. and McInnes, I. B. (2021) Managing cardiovascular risk in patients with rheumatic disease. Medical Clinics of North America, 105(2), pp. 247-262. (doi: 10.1016/j.mcna.2020.09.010) (PMID:33589100)

Thom, G. et al. (2021) Weight loss induced increase in fasting ghrelin concentration is a predictor of weight regain: evidence from the Diabetes Remission Clinical Trial. Diabetes, Obesity and Metabolism, 23(3), pp. 711-719. (doi: 10.1111/dom.14274) (PMID:33369058)

Lee, M. M.Y. et al. (2021) Effect of empagliflozin on left ventricular volumes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF). Circulation, 143(6), pp. 516-525. (doi: 10.1161/CIRCULATIONAHA.120.052186) (PMID:33186500) (PMCID:PMC7864599)

Al Ozairi, E. et al. (2021) Skeletal muscle and metabolic health – how do we increase muscle mass and function in people with type 2 diabetes. Journal of Clinical Endocrinology and Metabolism, 106(2), pp. 309-317. (doi: 10.1210/clinem/dgaa835) (PMID:33336682)

Bhopal, R. et al. (2021) Diabetes incidence in a high-risk UK population at 7 years: linkage of the Prevention of Diabetes and Obesity in South Asians (PODOSA) trial to the Scottish Diabetes Register. Diabetic Medicine, 38(2), e14369. (doi: 10.1111/dme.14369) (PMID:32738831)

Chiesa, S. T. et al. (2021) Determinants of intima-media thickness in the young: the ALSPAC Study. JACC: Cardiovascular Imaging, 14(2), pp. 468-478. (doi: 10.1016/j.jcmg.2019.08.026) (PMID:31607674) (PMCID:PMC7851110)

Donin, A. S. et al. (2021) Evaluating an intervention to increase cereal fiber intake in children: a randomized controlled feasibility trial. Journal of Nutrition, 151(2), pp. 379-386. (doi: 10.1093/jn/nxaa347) (PMID:33296467) (PMCID:PMC7849987)

Gerstein, H. C., Branch, K., Heenan, L., Del Prato, S., Khurmi, N. S., Lam, C. S.P., Pratley, R., Rosenstock, J. and Sattar, N. (2021) Design and baseline characteristics of the AMPLITUDE-O cardiovascular outcomes trial of efpeglenatide, a weekly glucagon-like peptide-1 receptor agonist. Diabetes, Obesity and Metabolism, 23(2), pp. 318-323. (doi: 10.1111/dom.14223) (PMID:33026143)

Hastie, C. , Pell, J. and Sattar, N. (2021) Vitamin D and COVID-19 infection and mortality in UK Biobank. European Journal of Nutrition, 60, pp. 545-548. (doi: 10.1007/s00394-020-02372-4) (PMID:32851419) (PMCID:PMC7449523)

Inzucchi, S. E., Davies, M. J., Khunti, K., Trivedi, P., George, J. T., Zwiener, I., Johansen, O. E. and Sattar, N. (2021) Empagliflozin treatment effects across categories of baseline HbA1c, body weight and blood pressure as an add-on to metformin in patients with type 2 diabetes. Diabetes, Obesity and Metabolism, 23(2), pp. 425-433. (doi: 10.1111/dom.14234) (PMID:33084149) (PMCID:PMC7839733)

Maznyczka, A. M. et al. (2021) Effect of coronary flow on intracoronary alteplase: a prespecified analysis from a randomised trial. Heart, 107(4), pp. 299-312. (doi: 10.1136/heartjnl-2020-317828) (PMID:33436493)

McGurnaghan, S. J. et al. (2021) Risks of and risk factors for COVID-19 disease in people with diabetes: a cohort study of the total population of Scotland. Lancet Diabetes and Endocrinology, 9(2), pp. 82-93. (doi: 10.1016/S2213-8587(20)30405-8) (PMID:33357491) (PMCID:PMC7832778)

Lagou, V. et al. (2021) Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nature Communications, 12, 24. (doi: 10.1038/s41467-020-19366-9) (PMID:33402679) (PMCID:PMC7785747)

Lyall, D. M. , Ward, J. , Banach, M., Smith, G. D., Gill, J. G. , Pell, J. P. , Holmes, M. V. and Sattar, N. (2021) PCSK9 genetic variants and cognitive abilities: a large-scale Mendelian randomization study. Archives of Medical Science, 17(1), pp. 241-244. (doi: 10.5114/aoms/127226)

Sattar, N. , Boyle, J. G. and Al-Ozairi, E. (2021) Testosterone replacement to prevent type 2 diabetes? Not just yet. Lancet Diabetes and Endocrinology, 9(1), pp. 5-6. (doi: 10.1016/S2213-8587(20)30373-9) (PMID:33338416)

Anderson, A. S. et al. (2021) A novel approach to increasing community capacity for weight management a volunteer-delivered programme (ActWELL) initiated within breast screening clinics: a randomised controlled trial. International Journal of Behavioral Nutrition and Physical Activity, 18, 34. (doi: 10.1186/s12966-021-01099-7) (PMID:33676538) (PMCID:PMC7936444)

Anderson, J. J. et al. (2021) Ethnic differences in prevalence of actionable HbA1c levels in UK Biobank: implications for screening. BMJ Open Diabetes Research and Care, 9(1), e002176. (doi: 10.1136/bmjdrc-2021-002176) (PMID:34353880) (PMCID:PMC8344314)

Edqvist, J., Rawshani, A., Rawshani, A., Adiels, M., Franzén, S., Bjorck, L., Svensson, A.-M., Lind, M., Sattar, N. and Rosengren, A. (2021) Trajectories in HbA1c and other risk factors among adults with type 1 diabetes by age at onset. BMJ Open Diabetes Research and Care, 9(1), e002187. (doi: 10.1136/bmjdrc-2021-002187) (PMID:34059526) (PMCID:PMC8169495)

2020

Goncalves Soares, A., Kilpi, F., Fraser, A., Nelson, S. M. , Sattar, N. , Welsh, P. I. , Tilling, K. and Lawlor, D. A. (2020) Longitudinal changes in reproductive hormones through the menopause transition in the Avon Longitudinal Study of Parents and Children (ALSPAC). Scientific Reports, 10, 21258. (doi: 10.1038/s41598-020-77871-9) (PMID:33277550) (PMCID:PMC7718240)

Mangion, K. et al. (2020) The Chief Scientist Office cardiovascular and pulmonary imaging in SARS Coronavirus disease-19 (CISCO-19) study. Cardiovascular Research, 116(14), pp. 2185-2196. (doi: 10.1093/cvr/cvaa209) (PMID:32702087) (PMCID:PMC7454350)

Al-Mrabeh, A., Hollingsworth, K. G., Shaw, J. A.M., McConnachie, A. , Sattar, N. , Lean, M. E.J. and Taylor, R. (2020) 2-year remission of type 2 diabetes and pancreas morphology: a post-hoc analysis of the DiRECT open-label, cluster-randomised trial. Lancet Diabetes and Endocrinology, 8(12), pp. 939-948. (doi: 10.1016/S2213-8587(20)30303-X) (PMID:33031736)

Angwin, C. et al. (2020) TriMaster: randomised double-blind crossover study of a DPP4 inhibitor, SGLT2 inhibitor and thiazolidinedione as second-line or third-line therapy in patients with type 2 diabetes who have suboptimal glycaemic control on metformin treatment with or without a sulfonylurea—a MASTERMIND study protocol. BMJ Open, 10(12), e042784. (doi: 10.1136/bmjopen-2020-042784) (PMID:33371044) (PMCID:PMC7754630)

Ferguson, A. C. et al. (2020) Association of SBP and BMI with cognitive and structural brain phenotypes in UK Biobank. Journal of Hypertension, 38(12), pp. 2482-2489. (doi: 10.1097/HJH.0000000000002579) (PMID:32665523)

Surendran, P. et al. (2020) Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nature Genetics, 52(12), pp. 1314-1332. (doi: 10.1038/s41588-020-00713-x) (PMID:33230300) (PMCID:PMC7610439)

Ho, F. K. et al. (2020) Modifiable and non-modifiable risk factors for COVID-19, and comparison to risk factors for influenza and pneumonia: results from a UK Biobank prospective cohort study. BMJ Open, 10, e040402. (doi: 10.1136/bmjopen-2020-040402) (PMID:33444201) (PMCID:PMC7678347)

Petermann-Rocha, F. et al. (2020) Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank. BMC Medicine, 18, 355. (doi: 10.1186/s12916-020-01822-4) (PMID:33167965) (PMCID:PMC7652674)

Ho, F. K. et al. (2020) Is older age associated with COVID-19 mortality in the absence of other risk factors? General population cohort study of 470,034 participants. PLoS ONE, 15(11), e0241824. (doi: 10.1371/journal.pone.0241824) (PMID:33152008) (PMCID:PMC7644030)

Foster, H. M.E. , Ho, F. K., Sattar, N. , Welsh, P. , Pell, J. P. , Gill, J. M.R. , Gray, S. R. and Celis-Morales, C. A. (2020) Understanding how much TV is too much: a non-linear analysis of the association between television viewing time and adverse health outcomes. Mayo Clinic Proceedings, 95(11), pp. 2429-2441. (doi: 10.1016/j.mayocp.2020.04.035) (PMID:32713607)

McCartney, P. J. et al. (2020) Low-dose intracoronary alteplase during primary percutaneous coronary intervention in patients with acute myocardial infarction: the T-TIME three-arm RCT. Efficacy and Mechanism Evaluation, 7(5), (doi: 10.3310/eme07050) (PMID:33175484)

Morrow, A. J. et al. (2020) Rationale and design of the Medical Research Council precision medicine with Zibotentan in microvascular angina (PRIZE) trial. American Heart Journal, 229, pp. 70-80. (doi: 10.1016/j.ahj.2020.07.007) (PMID:32942043)

Hrund Björnsdottir, H., Rawshani, A., Rawshani, A., Franzén, S., Svensson, A.-M., Sattar, N. and Gudbjörnsdottir, S. (2020) A national observation study of cancer incidence and mortality risks in type 2 diabetes compared to the background population over time. Scientific Reports, 10, 17376. (doi: 10.1038/s41598-020-73668-y) (PMID:33060631) (PMCID:PMC7566479)

Packer, M. et al. (2020) Cardiovascular and renal outcomes with empagliflozin in heart failure. New England Journal of Medicine, 383(15), pp. 1413-1424. (doi: 10.1056/NEJMoa2022190) (PMID:32865377)

Barron, E. et al. (2020) Associations of type 1 and type 2 diabetes with COVID-19-related mortality in England: a whole-population study. Lancet Diabetes and Endocrinology, 8(10), pp. 813-822. (doi: 10.1016/S2213-8587(20)30272-2) (PMID:32798472) (PMCID:PMC7426088)

Holman, N. et al. (2020) Risk factors for COVID-19-related mortality in people with type 1 and type 2 diabetes in England: a population-based cohort study. Lancet Diabetes and Endocrinology, 8(10), pp. 823-833. (doi: 10.1016/S2213-8587(20)30271-0) (PMID:32798471) (PMCID:PMC7426091)

Donnelly, L. A., Dennis, J. M., Coleman, R. L., Sattar, N. , Hattersley, A. T., Holman, R. R. and Pearson, E. R. (2020) Risk of anemia with metformin use in type 2 diabetes: a MASTERMIND study. Diabetes Care, 43(10), pp. 2493-2499. (doi: 10.2337/dc20-1104) (PMID:32801130) (PMCID:PMC7510037)

Erzurumluoglu, A. M. et al. (2020) Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. Molecular Psychiatry, 25(10), pp. 2392-2409. (doi: 10.1038/s41380-018-0313-0) (PMID:30617275) (PMCID:PMC7515840)

Lyall, D. M. et al. (2020) Association between APOE e4 and white matter hyperintensity volume, but not total brain volume or white matter integrity. Brain Imaging and Behavior, 14(5), pp. 1468-1476. (doi: 10.1007/s11682-019-00069-9) (PMID:30903549) (PMCID:PMC7572345)

Martinez-Amezcua, P. et al. (2020) The upcoming epidemic of heart failure in South Asia. Circulation: Heart Failure, 13(10), e007218. (doi: 10.1161/CIRCHEARTFAILURE.120.007218) (PMID:32962410)

Ford, T. J. et al. (2020) Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction. European Heart Journal, 41(34), pp. 3239-3252. (doi: 10.1093/eurheartj/ehz915) (PMID:31972008) (PMCID:PMC7557475)

Caparrotta, T. M. et al. (2020) Prescribing paradigm shift? Applying the 2019 European Society of Cardiology-led guidelines on diabetes, prediabetes, and cardiovascular disease to assess eligibility for sodium-glucose cotransporter 2 inhibitors or glucagon-like peptide 1 receptor agonists as first-line monotherapy (or add-on to metformin monotherapy) in type 2 diabetes in Scotland. Diabetes Care, 43(9), pp. 2034-2041. (doi: 10.2337/dc20-0120) (PMID:32581068)

Ferrannini, E., Murthy, A. C., Lee, Y.-h., Muscelli, E., Weiss, S., Ostroff, R. M., Sattar, N. , Williams, S. A. and Ganz, P. (2020) Mechanisms of sodium-glucose cotransporter-2 inhibition: insights from large-scale proteomics. Diabetes Care, 43(9), pp. 2183-2189. (doi: 10.2337/dc20-0456) (PMID:32527800)

Sattar, N. et al. (2020) BMI and future risk for COVID-19 infection and death across sex, age and ethnicity: preliminary findings from UK biobank. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 14(5), pp. 1149-1151. (doi: 10.1016/j.dsx.2020.06.060) (PMID:32668401) (PMCID:PMC7326434)

McQueenie, R. et al. (2020) Multimorbidity, polypharmacy, and COVID-19 infection within the UK Biobank cohort. PLoS ONE, 15(8), e0238091. (doi: 10.1371/journal.pone.0238091) (PMID:32817712) (PMCID:PMC7440632)

Ferguson, A. C. et al. (2020) Alzheimer’s disease susceptibility gene apolipoprotein e (APOE) and blood biomarkers in UK Biobank (N=395,769). Journal of Alzheimer's Disease, 76(4), pp. 1541-1551. (doi: 10.3233/JAD-200338) (PMID:32651323)

O’Reilly, J. E. et al. (2020) Time trends in deaths before age 50 years in people with type 1 diabetes: a nationwide analysis from Scotland 2004–2017. Diabetologia, 63(8), pp. 1626-1636. (doi: 10.1007/s00125-020-05173-w) (PMID:32451572) (PMCID:PMC7351819)

Petermann-Rocha, F., Ho, K. F., Welsh, P. , Mackay, D. , Brown, R., Gill, J. M.R. , Sattar, N. , Gray, S. R. , Pell, J. P. and Celis-Morales, C. A. (2020) Physical capability markers used to define sarcopenia and their association with cardiovascular and respiratory outcomes and all-cause mortality: a prospective study from UK Biobank. Maturitas, 138, pp. 69-75. (doi: 10.1016/j.maturitas.2020.04.017) (PMID:32471663)

Wright, A. K., Welsh, P. , Gill, J. M.R. , Kontopantelis, E., Emsley, R., Buchan, I., Ashcroft, D. M., Rutter, M. K. and Sattar, N. (2020) Age-, sex- and ethnicity-related differences in body weight, blood pressure, HbA1c and lipid levels at the diagnosis of type 2 diabetes relative to people without diabetes. Diabetologia, 63, pp. 1542-1553. (doi: 10.1007/s00125-020-05169-6) (PMID:32435821) (PMCID:PMC7351865)

Sattar, N. and Welsh, P. (2020) The obesity paradox in secondary prevention: a weighty intervention or a wait for more evidence? European Heart Journal, 41(28), pp. 2678-2680. (doi: 10.1093/eurheartj/ehaa398) (PMID:32459827)

Boal, A. H., Gill, J. M.R. and Sattar, N. (2020) Shorter sleep: a new potential target to address cardiovascular and metabolic risk? Cardiovascular Research, 116(8), pp. 1407-1409. (doi: 10.1093/cvr/cvz330) (PMID:31834352)

Hastie, C. E. et al. (2020) Vitamin D concentrations and COVID-19 infection in UK Biobank. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 14(4), pp. 561-565. (doi: 10.1016/j.dsx.2020.04.050) (PMID:32413819) (PMCID:PMC7204679)

Sattar, N. , McInnes, I. B. and McMurray, J. J.V. (2020) Obesity a risk factor for severe COVID-19 infection: multiple potential mechanisms. Circulation, 142(1), pp. 4-6. (doi: 10.1161/CIRCULATIONAHA.120.047659) (PMID:32320270)

Al Ozairi, E. et al. (2020) Protocol for a randomised controlled trial to investigate the effect of home and gym-based resistance exercise training on glycaemic control, body composition and muscle strength. Trials, 21, 557. (doi: 10.1186/s13063-020-04480-2) (PMID:32571396) (PMCID:PMC7310149)

Harrison, E. M. et al. (2020) Ethnicity and outcomes from COVID-19: the ISARIC CCP-UK prospective observational cohort study of hospitalised patients. SSRN Electronic Journal, (doi: 10.2139/ssrn.3618215) (Submitted)

Ho, F. K., Celis-Morales, C. , Gray, S. R. , Petermann-Rocha, F., Lyall, D. , Mackay, D. , Sattar, N. , Minnis, H. and Pell, J. P. (2020) Child maltreatment and cardiovascular disease: quantifying mediation pathways using UK Biobank. BMC Medicine, 18, 143. (doi: 10.1186/s12916-020-01603-z) (PMID:32527275) (PMCID:PMC7291652)

Henson, J. et al. (2020) Predictors of the acute postprandial response to breaking up prolonged sitting. Medicine and Science in Sports and Exercise, 52(6), pp. 1385-1393. (doi: 10.1249/MSS.0000000000002249) (PMID:31895295)

Niedzwiedz, C. L. et al. (2020) Ethnic and socioeconomic differences in SARS-CoV-2 infection: prospective cohort study using UK Biobank. BMC Medicine, 18, 160. (doi: 10.1186/s12916-020-01640-8) (PMID:32466757) (PMCID:PMC7255908)

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Welsh, C. E. et al. (2020) Grip strength and walking pace and cardiovascular disease risk prediction in 406,834 UK Biobank participants. Mayo Clinic Proceedings, 95(5), pp. 879-888. (doi: 10.1016/j.mayocp.2019.12.032) (PMID:32299669)

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Anderson, J. J. , Gray, S. R. , Welsh, P. , Mackay, D. F. , Celis-Morales, C. A. , Lyall, D. M. , Forbes, J., Sattar, N. , Gill, J. M.R. and Pell, J. P. (2020) The associations of sugar-sweetened, artificially sweetened and naturally sweet juices with all-cause mortality in 198,285 UK Biobank participants: a prospective cohort study. BMC Medicine, 18(1), 97. (doi: 10.1186/s12916-020-01554-5) (PMID:32326961)

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White, S. L. et al. (2020) Metabolic phenotyping by treatment modality in obese women with gestational diabetes suggests diverse pathophysiology: An exploratory study. PLoS ONE, 15(4), e0230658. (doi: 10.1371/journal.pone.0230658) (PMID:32240196) (PMCID:PMC7117764)

Sattar, N. (2020) Type 2 diabetes-related sex differences in cardiovascular risk: reasons, ramifications and clinical realities. European Heart Journal, 41(13), pp. 1354-1356. (doi: 10.1093/eurheartj/ehz914) (PMID:31860071)

Zhyzhneuskaya, S. V., Al-Mrabeh, A., Peters, C., Barnes, A., Aribisala, B., Hollingsworth, K. G., McConnachie, A. , Sattar, N. , Lean, M. E.J. and Taylor, R. (2020) Time course of normalization of functional β-cell capacity in the Diabetes Remission Clinical Trial after weight loss in type 2 diabetes. Diabetes Care, 43(4), pp. 813-820. (doi: 10.2337/dc19-0371) (PMID:32060017)

Welsh, C. et al. (2020) Association of injury related hospital admissions with commuting by bicycle in the UK: prospective population based study. British Medical Journal, 368, m336. (doi: 10.1136/bmj.m336) (PMID:32161038) (PMCID:PMC7190046)

Zijlstra, L. E., Trompet, S., Mooijaart, S. P., van Buren, M., Sattar, N. , Stott, D. J. and Jukema, J. W. (2020) The association of kidney function and cognitive decline in older patients at risk of cardiovascular disease: a longitudinal data analysis. BMC Nephrology, 21, 81. (doi: 10.1186/s12882-020-01745-5) (PMID:32138689) (PMCID:PMC7059260)

Ho, F. K. et al. (2020) Associations of fat and carbohydrate intake with cardiovascular disease and mortality: prospective cohort study of UK Biobank participants. British Medical Journal, 368(8238), m688. (doi: 10.1136/bmj.m688) (PMID:32188587)

Lee, M. M.Y. , Petrie, M. C. , McMurray, J. J.V. and Sattar, N. (2020) How do SGLT2 (sodium-glucose cotransporter 2) inhibitors and GLP-1 (glucagon-like peptide-1) receptor agonists reduce cardiovascular outcomes? Arteriosclerosis, Thrombosis, and Vascular Biology, 40(3), pp. 506-522. (doi: 10.1161/atvbaha.119.311904) (PMID:31996025)

Sattar, N. , Gill, J. M.R. and Alazawi, W. (2020) Improving prevention strategies for cardiometabolic disease. Nature Medicine, 26(3), pp. 320-325. (doi: 10.1038/s41591-020-0786-7) (PMID:32152584)

Al-Mrabeh, A. et al. (2020) Hepatic lipoprotein export and remission of human type 2 diabetes after weight loss. Cell Metabolism, 31(2), 233-249.e4. (doi: 10.1016/j.cmet.2019.11.018) (PMID:31866441)

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Garton, M., McInnes, I. B. and Sattar, N. (2020) Comment on: Lipid screening and statins alongside disease-modifying anti-rheumatic drugs for patients with rheumatoid arthritis. Rheumatology, 59(2), pp. 453-454. (doi: 10.1093/rheumatology/kez613) (PMID:31873738) (PMCID:31873738)

Rankin, A. J. et al. (2020) Comparing the interobserver reproducibility of different regions of interest on multi-parametric renal magnetic resonance imaging in healthy volunteers, patients with heart failure and renal transplant recipients. Magnetic Resonance Materials in Physics, Biology and Medicine, 33, pp. 103-112. (doi: 10.1007/s10334-019-00809-4) (PMID:31823275) (PMCID:PMC7021749)

Sillars, A., Ho, F. K., Pell, J. P. , Gill, J. M.R. , Sattar, N. , Gray, S. and Celis-Morales, C. (2020) Sex differences in the association of risk factors for heart failure incidence and mortality. Heart, 106(3), pp. 203-212. (doi: 10.1136/heartjnl-2019-314878) (PMID:31366573)

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Shah, S. et al. (2020) Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure. Nature Communications, 11, 163. (doi: 10.1038/s41467-019-13690-5) (PMID:31919418) (PMCID:PMC6952380)

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Shivakumar, O., Sattar, N. and Wheeler, D. C. (2020) Sodium-glucose cotransporter 2 inhibitor effects on cardiovascular outcomes in chronic kidney disease. Nephrology Dialysis Transplantation, 35(Supple), i43-i47. (doi: 10.1093/ndt/gfz292) (PMID:32003831) (PMCID:PMC6993195)

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Lim, S., Oh, T. J., Dawson, J. and Sattar, N. (2020) Diabetes drugs and stroke risk: intensive versus conventional glucose‐lowering strategies, and implications of recent cardiovascular outcome trials. Diabetes, Obesity and Metabolism, 22(1), pp. 6-15. (doi: 10.1111/dom.13850) (PMID:31379119)

Yates, T. et al. (2020) Metabolic effects of breaking prolonged sitting with standing or light walking in older South Asians and White Europeans: a randomized acute study. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 75(1), pp. 139-146. (doi: 10.1093/gerona/gly252) (PMID:30403772) (PMCID:PMC6909896)

Coll, A. P. et al. (2020) GDF15 mediates the effects of metformin on body weight and energy balance. Nature, 578, pp. 444-448. (doi: 10.1038/s41586-019-1911-y) (PMID:31875646) (PMCID:PMC7234839)

Henson, J., Edwardson, C. L., Davies, M. J., Gill, J. M.R. , Heaney, L. M., Khunti, K., Ng, L., Sattar, N. , Zaccardi, F. and Yates, T. (2020) Physical activity and lipidomics in a population at high risk of type 2 diabetes mellitus. Journal of Sports Sciences, 38(10), pp. 1150-1160. (doi: 10.1080/02640414.2020.1744836) (PMID:32228122)

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Rey-Lopez, J. P., Ho, F. K.W., Foster, H. M.E. , Petermann-Rocha, F., Sattar, N. , Pell, J. P. , Gill, J. M.R. , Gray, S. R. and Celis-Morales, C. A. (2020) Does the association between physical capability and mortality differ by deprivation? Findings from the UK Biobank population-based cohort study. Journal of Sports Sciences, 38(23), pp. 2732-2739. (doi: 10.1080/02640414.2020.1797438) (PMID:32723006)

Robertson, J., Lindgren, M., Schaufelberger, M., Adiels, M., Björck, L., Lundberg, C. E., Sattar, N. , Rosengren, A. and Åberg, M. (2020) Body Mass Index in young women and risk of cardiomyopathy: a long-term follow-up study in Sweden. Circulation, 141(7), pp. 520-529. (doi: 10.1161/CIRCULATIONAHA.119.044056) (PMID:32065765) (PMCID:PMC7017947)

2019

Badjatiya, A. et al. (2019) Clinical outcomes in patients with type 2 diabetes mellitus and peripheral artery disease. Circulation: Cardiovascular Interventions, 12(12), e008018. (doi: 10.1161/CIRCINTERVENTIONS.119.008018) (PMID:31752517)

Eastwood, S. V., Chaturvedi, N., Sattar, N. , Welsh, P. I. , Hughes, A. D. and Tillin, T. (2019) Impact of kidney function on cardiovascular risk and mortality: a comparison of South Asian and European cohorts. American Journal of Nephrology, 50(6), pp. 425-433. (doi: 10.1159/000503873) (PMID:31665726) (PMCID:PMC6892637)

Ferguson, L. D. , Brown, R., Celis-Morales, C. , Welsh, P. , Lyall, D. M. , Pell, J. P. , McInnes, I. B. , Siebert, S. and Sattar, N. (2019) Association of central adiposity with psoriasis, psoriatic arthritis and rheumatoid arthritis: a cross-sectional study of the UK Biobank. Rheumatology, 58(12), pp. 2137-2142. (doi: 10.1093/rheumatology/kez192) (PMID:31131407) (PMCID:PMC6880847)

Ford, T. J. et al. (2019) Ischemia and no obstructive coronary artery disease: prevalence and correlates of coronary vasomotion disorders. Circulation: Cardiovascular Interventions, 12(12), e008126. (doi: 10.1161/CIRCINTERVENTIONS.119.008126) (PMID:31833416) (PMCID:PMC6924940)

Sillars, A. and Sattar, N. (2019) Management of lipid abnormalities in patients with diabetes. Current Cardiology Reports, 21(11), 147. (doi: 10.1007/s11886-019-1246-1) (PMID:31758270) (PMCID:PMC6874523)

Tillin, T. et al. (2019) Yoga and Cardiovascular Health Trial (YACHT): a UK-based randomised mechanistic study of a yoga intervention plus usual care versus usual care alone following an acute coronary event. BMJ Open, 9(11), e030119. (doi: 10.1136/bmjopen-2019-030119) (PMID:31685500) (PMCID:PMC6858127)

Ferguson, L. , Welsh, P. , Brown, R., Tindell, A., Kerrigan, S., Sattar, N. , McInnes, I. and Siebert, S. (2019) Effect of Phosphodiesterase 4 Inhibition with Apremilast on Cardiometabolic Outcomes in Psoriatic Arthritis – Initial Results from the Immune Metabolic Associations in Psoriatic Arthritis (IMAPA) Study. In: 2019 ACR/ARP Annual Meeting, Atlanta, GA, 8-13 November 2019,

Lees, J. S. et al. (2019) Glomerular filtration rate by differing measures, albuminuria and prediction of cardiovascular disease, mortality and end-stage kidney disease. Nature Medicine, 25, pp. 1753-1760. (doi: 10.1038/s41591-019-0627-8) (PMID:31700174) (PMCID:PMC6858876)

Sattar, N. and Preiss, D. (2019) Research digest: new horizons in heart failure therapy. Lancet Diabetes and Endocrinology, 7(11), p. 832. (doi: 10.1016/S2213-8587(19)30315-8) (PMID:31621593)

Sillars, A. et al. (2019) Association of fitness and grip-strength with heart failure: findings from the UK Biobank population-based study. Mayo Clinic Proceedings, 94(11), pp. 2230-2240. (doi: 10.1016/j.mayocp.2019.04.041) (PMID:31685151)

Steell, L. et al. (2019) Dose-response associations of cardiorespiratory fitness with all-cause mortality and incidence and mortality of cancer and cardiovascular and respiratory diseases: the UK Biobank cohort study. British Journal of Sports Medicine, 53(21), pp. 1371-1378. (doi: 10.1136/bjsports-2018-099093) (PMID:30796106)

Clark, D. W. et al. (2019) Associations of autozygosity with a broad range of human phenotypes. Nature Communications, 10, 4957. (doi: 10.1038/s41467-019-12283-6) (PMID:31673082) (PMCID:PMC6823371)

Schmidt, A. F. et al. (2019) Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. BMC Cardiovascular Disorders, 19, 240. (doi: 10.1186/s12872-019-1187-z) (PMID:31664920) (PMCID:PMC6820948)

Alexander, M. et al. (2019) Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults. British Medical Journal, 367, l5367. (doi: 10.1136/bmj.l5367) (PMID:31594780) (PMCID:PMC6780322)

Anker, S. D. et al. (2019) Evaluation of the effects of sodium–glucose co‐transporter 2 inhibition with empagliflozin on morbidity and mortality in patients with chronic heart failure and a preserved ejection fraction: rationale for and design of the EMPEROR‐Preserved Trial. European Journal of Heart Failure, 21(10), pp. 1279-1287. (doi: 10.1002/ejhf.1596) (PMID:31523904)

Lee, M. M.Y. , Sattar, N. , McMurray, J. J.V. and Packard, C. J. (2019) Statins in the prevention and treatment of heart failure: a review of the evidence. Current Atherosclerosis Reports, 21(10), 41. (doi: 10.1007/s11883-019-0800-z)

Muilwijk, M. et al. (2019) Contribution of type 2 diabetes to all-cause mortality, cardiovascular disease incidence and cancer incidence in white Europeans and South Asians: findings from the UK Biobank population-based cohort study. BMJ Open Diabetes Research and Care, 7(1), e000765. (doi: 10.1136/bmjdrc-2019-000765) (PMID:31908795) (PMCID:PMC6936483)

Ochs, A., McGurnaghan, S., Black, M. W., Leese, G. P., Philip, S., Sattar, N. , Styles, C., Wild, S. H., McKeigue, P. M. and Colhoun, H. M. (2019) Use of personalised risk-based screening schedules to optimise workload and sojourn time in screening programmes for diabetic retinopathy: a retrospective cohort study. PLoS Medicine, 16(10), e1002945. (doi: 10.1371/journal.pmed.1002945)

Packer, M. et al. (2019) Evaluation of the effect of sodium–glucose co‐transporter 2 inhibition with empagliflozin on morbidity and mortality of patients with chronic heart failure and a reduced ejection fraction: rationale for and design of the EMPEROR‐Reduced trial. European Journal of Heart Failure, 21(10), pp. 1270-1278. (doi: 10.1002/ejhf.1536) (PMID:31584231)

Mazidi, M., Katsiki, N., Mikhailidis, D. P., Sattar, N. and Banach, M. (2019) Lower carbohydrate diets and all-cause and cause-specific mortality: a population-based cohort study and pooling of prospective studies. European Heart Journal, 40(34), pp. 2870-2879. (doi: 10.1093/eurheartj/ehz174) (PMID:31004146)

Ho, F. K.W. et al. (2019) The association between handgrip strength and future health outcomes does not differ if grip strength is used in absolute or relative terms: a prospective cohort study. Age and Ageing, 48(5), pp. 683-691. (doi: 10.1093/ageing/afz068) (PMID:31204772)

Iliodromiti, S., Sattar, N. , Delles, C. , Nelson, S. M. , Gill, J. M.R. and Lumsden, M. (2019) Menopausal hot flashing and endothelial function in two vascular beds: findings from a cross-sectional study of postmenopausal women. Menopause, 26(9), pp. 1002-1009. (doi: 10.1097/GME.0000000000001386) (PMID:31453962)

Kitas, G. D. et al. (2019) A multicenter, randomized, placebo‐controlled trial of atorvastatin for the primary prevention of cardiovascular events in patients with rheumatoid arthritis. Arthritis and Rheumatology, 71(9), pp. 1437-1449. (doi: 10.1002/art.40892) (PMID:30983166) (PMCID:PMC6771601)

Kristensen, S. L., Rorth, R., Jhund, P. S. , Docherty, K. , Sattar, N. , Preiss, D. , Kober, L., Petrie, M. C. and McMurray, J. J.V. (2019) Cardiovascular, mortality and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials. Lancet Diabetes and Endocrinology, 7(10), pp. 776-785. (doi: 10.1016/S2213-8587(19)30249-9) (PMID:31422062)

Mackay, A., Mackay, D.F. , Celis-Morales, C.A. , Lyall, D.M. , Gray, S.R. , Sattar, N. , Gill, J.M.R. , Pell, J.P. and Anderson, J.J. (2019) The association between driving time and unhealthy lifestyles: a cross-sectional, general population study of 386 493 UK Biobank participants. Journal of Public Health, 41(3), pp. 527-534. (doi: 10.1093/pubmed/fdy155) (PMID:30239914)

Sattar, N. (2019) Diabetes management gains: teaching old dogs new tricks. Diabetic Medicine, 36(9), pp. 1072-1074. (doi: 10.1111/dme.14068) (PMID:31271670)

Tromp, J. et al. (2019) Microvascular disease in patients with diabetes with heart failure and reduced ejection versus preserved ejection fraction. Diabetes Care, 42(9), pp. 1792-1799. (doi: 10.2337/dc18-2515) (PMID:31292141)

Deelen, J. et al. (2019) A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals. Nature Communications, 10, 3346. (doi: 10.1038/s41467-019-11311-9) (PMID:31431621) (PMCID:PMC6702196)

Welsh, C. et al. (2019) Comparison of conventional lipoprotein tests and apolipoproteins in the prediction of cardiovascular disease: data from UK Biobank. Circulation, 140(7), pp. 542-552. (doi: 10.1161/CIRCULATIONAHA.119.041149) (PMID:31216866) (PMCID:PMC6693929)

Gray, S. et al. (2019) Do physical activity, commuting mode, cardiorespiratory fitness and sedentary behaviours modify the genetic predisposition to higher BMI? Findings from a UK Biobank study. International Journal of Obesity, 43, pp. 1526-1538. (doi: 10.1038/s41366-019-0381-5) (PMID:31168053)

Jenum, A. K. et al. (2019) Effects of dietary and physical activity interventions on the risk of type 2 diabetes in South Asians: meta-analysis of individual participant data from randomised controlled trials. Diabetologia, 62(8), pp. 1337-1348. (doi: 10.1007/s00125-019-4905-2) (PMID:31201437)

Mair, C. et al. (2019) Glycaemic control trends in people with type 1 diabetes in Scotland 2004–2016. Diabetologia, 62(8), pp. 1375-1384. (doi: 10.1007/s00125-019-4900-7) (PMID:31104095) (PMCID:PMC6647722)

Welsh, C. E. , Welsh, P. , Jhund, P. , Sattar, N. and Mark, P. B. (2019) Response by Welsh et al to letter regarding article “Urinary sodium excretion, blood pressure, and risk of future cardiovascular disease and mortality in subjects without prior cardiovascular disease”. Hypertension, 74, e27-e28. (doi: 10.1161/HYPERTENSIONAHA.119.13349) (PMID:31230548)

Dangardt, F. et al. (2019) Association between fat mass through adolescence and arterial stiffness: a population-based study from The Avon Longitudinal Study of Parents and Children. Lancet Child and Adolescent Health, 3(7), pp. 474-481. (doi: 10.1016/S2352-4642(19)30105-1) (PMID:31126896) (PMCID:PMC6558973)

Dennis, J. M., Henley, W. E., McGovern, A. P., Farmer, A. J., Sattar, N. , Holman, R. R., Pearson, E. R., Hattersley, A. T., Shields, B. M. and Jones, A. G. (2019) Time trends in prescribing of type 2 diabetes drugs, glycaemic response and risk factors: a retrospective analysis of primary care data, 2010–2017. Diabetes, Obesity and Metabolism, 21(7), pp. 1576-1584. (doi: 10.1111/dom.13687) (PMID:30828962) (PMCID:PMC6618851)

Edqvist, J., Rawshani, A., Adiels, M., Björck, L., Lind, M., Svensson, A.-M., Gudbjörnsdottir, S., Sattar, N. and Rosengren, A. (2019) BMI, mortality, and cardiovascular outcomes in type 1 diabetes: findings against an obesity paradox. Diabetes Care, 42(7), pp. 1297-1304. (doi: 10.2337/dc18-1446) (PMID:31048408)

Robertson, J., Schaufelberger, M., Lindgren, M., Adiels, M., Schiöler, L., Torén, K., McMurray, J. , Sattar, N. , Åberg, M. and Rosengren, A. (2019) Higher body mass index in adolescence predicts cardiomyopathy risk in midlife: long-term follow-up among Swedish men. Circulation, 140, pp. 117-125. (doi: 10.1161/circulationaha.118.039132) (PMID:31132859) (PMCID:PMC6635044)

Lyall, D. M. et al. (2019) Assessing for interaction between APOE ε4, sex and lifestyle on cognitive abilities. Neurology, 92, e2691-e2698. (doi: 10.1212/WNL.0000000000007551) (PMID:31028125) (PMCID:PMC6556094)

Malik, R. et al. (2019) Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nature Genetics, (doi: 10.1038/s41588-019-0449-0) (PMID:31160810)

Brazel, D. M. et al. (2019) Exome chip meta-analysis fine maps causal variants and elucidates the genetic architecture of rare coding variants in smoking and alcohol use. Biological Psychiatry, 85(11), pp. 946-955. (doi: 10.1016/j.biopsych.2018.11.024) (PMID:30679032)

Haig, C. et al. (2019) Current smoking and prognosis after acute ST-segment elevation myocardial infarction: new pathophysiological insights. JACC: Cardiovascular Imaging, 12(6), pp. 993-1003. (doi: 10.1016/j.jcmg.2018.05.022) (PMID:30031700) (PMCID:PMC6547246)

Lean, M. E.J. and Sattar, N. (2019) Da Qing 30 years on: more reasons to extend diabetes prevention. Lancet Diabetes and Endocrinology, 7(6), pp. 417-419. (doi: 10.1016/S2213-8587(19)30138-X) (PMID:31031111)

Welsh, C. et al. (2019) Urinary sodium excretion, blood pressure and risk of future cardiovascular disease and mortality in subjects without prior cardiovascular disease. Hypertension, 73, pp. 1202-1209. (doi: 10.1161/HYPERTENSIONAHA.119.12726) (PMID:31067194)

Welsh, P. et al. (2019) Cardiac troponin T and troponin I in the general population: comparing and contrasting their genetic determinants and associations with outcomes. Circulation, 139(24), pp. 2754-2764. (doi: 10.1161/CIRCULATIONAHA.118.038529) (PMID:31014085) (PMCID:PMC6571179)

Wright, A. K., Kontopantelis, E., Emsley, R., Buchan, I., Mamas, M. A., Sattar, N. , Ashcroft, D. M. and Rutter, M. K. (2019) Cardiovascular risk and risk factor management in type 2 diabetes mellitus: a population-based cohort study assessing sex disparities. Circulation, 139(24), pp. 2742-2753. (doi: 10.1161/CIRCULATIONAHA.118.039100) (PMID:30986362)

Alexander, M. et al. (2019) Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts. BMC Medicine, 17, 95. (doi: 10.1186/s12916-019-1321-x)

Sattar, N. , Rawshani, A., Franzén, S., Rawshani, A., Svensson, A.-M., Rosengren, A., McGuire, D. K., Eliasson, B. and Gudbjörnsdottir, S. (2019) Age at diagnosis of type 2 diabetes mellitus and associations with cardiovascular and mortality risks findings from the Swedish National Diabetes Registry. Circulation, 139(19), pp. 2228-2237. (doi: 10.1161/CIRCULATIONAHA.118.037885) (PMID:30955347)

Ferreira, J. P. et al. (2019) Proteomic bioprofiles and mechanistic pathways of progression to heart failure: the HOMAGE study. Circulation, 12(5), e005897. (doi: 10.1161/CIRCHEARTFAILURE.118.005897) (PMID:31104495)

Lean, M. E.J. et al. (2019) Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial. Lancet Diabetes and Endocrinology, 7(5), pp. 344-355. (doi: 10.1016/S2213-8587(19)30068-3) (PMID:30852132)

Rawshani, A. et al. (2019) Relative prognostic importance and optimal levels of risk factors for mortality and cardiovascular outcomes in type 1 diabetes mellitus. Circulation, 139(16), pp. 1900-1912. (doi: 10.1161/CIRCULATIONAHA.118.037454) (PMID:30798638)

McGovern, A. P., Dennis, J. M., Shields, B. M., Hattersley, A. T., Pearson, E. R., Jones, A. G. and , (2019) What to do with diabetes therapies when HbA1c lowering is inadequate: add, switch, or continue? A MASTERMIND study. BMC Medicine, 17, 79. (doi: 10.1186/s12916-019-1307-8) (PMID:30979373) (PMCID:PMC6460517)

Celis-Morales, C. A. et al. (2019) The combination of physical activity and sedentary behaviors modifies the genetic predisposition to obesity. Obesity, 27(4), pp. 653-661. (doi: 10.1002/oby.22417) (PMID:30900409)

Kuh, D., Cooper, R., Sattar, N. , Welsh, P. , Hardy, R. and Ben-Shlomo, Y. (2019) Systemic inflammation and cardio-renal organ damage biomarkers in middle age are associated with physical capability up to 9 years later: findings from a British birth cohort study. Circulation, 139(17), pp. 1988-1999. (doi: 10.1161/CIRCULATIONAHA.118.037332) (PMID:30667283) (PMCID:PMC6485301)

Maznyczka, A. M. et al. (2019) Sex-based associations with microvascular injury and outcomes after ST-segment elevation myocardial infarction. Open Heart, 6(1), e000979. (doi: 10.1136/openhrt-2018-000979) (PMID:31168381) (PMCID:PMC6519583)

McGurnaghan, S. J. et al. (2019) The effect of dapagliflozin on glycaemic control and other cardiovascular disease risk factors in type 2 diabetes mellitus: a real-world observational study. Diabetologia, 62(4), pp. 621-632. (doi: 10.1007/s00125-018-4806-9) (PMID:30631892)

Patel, R. S. et al. (2019) Association of chromosome 9p21 with subsequent coronary heart disease events: a GENUIS-CHD study of individual participant data. Circulation: Genomic and Precision Medicine, 12(4), e002471. (doi: 10.1161/CIRCGEN.119.002471) (PMID:30897348)

Welsh, P. , Papacosta, O., Ramsay, S., Whincup, P., McMurray, J. , Wannamethee, G. and Sattar, N. (2019) High sensitivity troponin T and incident heart failure in older men: British Regional Heart Study. Journal of Cardiac Failure, 25(4), pp. 230-237. (doi: 10.1016/j.cardfail.2018.08.002) (PMID:30103019) (PMCID:PMC7083232)

Patel, R. et al. (2019) Subsequent event risk in individuals with established coronary heart disease: design and rationale of the GENIUS-CHD Consortium. Circulation: Genomic and Precision Medicine, (doi: 10.1161/CIRCGEN.119.002470) (PMID:30896328)

Rankin, N. J. , Burgess, K., Weidt, S., Wannamethee, G., Sattar, N. and Welsh, P. (2019) High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry. Annals of Clinical Biochemistry, 56(3), pp. 397-407. (doi: 10.1177/0004563219830432) (PMID:30832481) (PMCID:PMC6498755)

Celis-Morales, C. A. et al. (2019) Walking pace is associated with lower risk of all-cause and cause-specific mortality. Medicine and Science in Sports and Exercise, 51(3), pp. 472-480. (doi: 10.1249/MSS.0000000000001795) (PMID:30303933)

Read, S. H., Fischbacher, C. M., Colhoun, H. M., Gasevic, D., Kerssens, J. J., McAllister, D. A. , Sattar, N. and Wild, S. H. (2019) Trends in incidence and case fatality of acute myocardial infarction, angina and coronary revascularisation in people with and without type 2 diabetes in Scotland between 2006 and 2015. Diabetologia, 62(3), pp. 418-425. (doi: 10.1007/s00125-018-4796-7) (PMID:30656362) (PMCID:PMC7019674)

Steell, L. , Sillars, A., Welsh, P. , Iliodromiti, S., Wong, S.C. , Pell, J.P. , Sattar, N. , Gill, J.M.R. , Celis, C. and Gray, S.R. (2019) Associations of dietary protein intake with bone mineral density: an observational study in 70,215 UK Biobank participants. Bone, 120, pp. 38-43. (doi: 10.1016/j.bone.2018.10.003) (PMID:30292817)

Larsson, S. C. et al. (2019) Serum magnesium and calcium levels in relation to ischemic stroke. Neurology, 92(9), e944-e950. (doi: 10.1212/WNL.0000000000007001) (PMID:30804065) (PMCID:PMC6404465)

Sattar, N. (2019) Advances in the clinical management of type 2 diabetes: a brief history of the past 15 years and challenges for the future. BMC Medicine, 17, 46. (doi: 10.1186/s12916-019-1281-1) (PMID:30803451) (PMCID:PMC6390346)

Pennells, L. et al. (2019) Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies. European Heart Journal, 40(7), pp. 621-631. (doi: 10.1093/eurheartj/ehy653) (PMID:30476079) (PMCID:PMC6374687)

Wyke, S. et al. (2019) The effect of a programme to improve men's sedentary time and physical activity: the European Fans in Training (EuroFIT) randomised controlled trial. PLoS Medicine, 16(2), e1002736. (doi: 10.1371/journal.pmed.1002736) (PMID:30721231) (PMCID:PMC6363143)

Armitage, J. et al. (2019) Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials. Lancet, 393(10170), pp. 407-415. (doi: 10.1016/S0140-6736(18)31942-1) (PMID:30712900) (PMCID:PMC6429627)

Ferreira, J. P. et al. (2019) Potential spironolactone effects on collagen metabolism biomarkers in patients with uncontrolled blood pressure. Heart, 105(4), pp. 307-314. (doi: 10.1136/heartjnl-2018-313182) (PMID:30121630)

Petrie, J. R. and Sattar, N. (2019) Excess cardiovascular risk in type 1 diabetes mellitus. Circulation, 139(6), pp. 744-747. (doi: 10.1161/circulationaha.118.038137) (PMID:30715940)

Budu-Aggrey, A. et al. (2019) Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study. PLoS Medicine, 16(1), e1002739. (doi: 10.1371/journal.pmed.1002739) (PMID:30703100) (PMCID:PMC6354959)

Mills, H. L. et al. (2019) The effect of a lifestyle intervention in obese pregnant women on gestational metabolic profiles: findings from the UK Pregnancies Better Eating and Activity Trial (UPBEAT) randomised controlled trial. BMC Medicine, 17, 15. (doi: 10.1186/s12916-018-1248-7) (PMID:30661507) (PMCID:PMC6340185)

McCartney, P. J. et al. (2019) Effect of low-dose intracoronary alteplase during primary percutaneous coronary intervention on microvascular obstruction in patients with acute myocardial infarction: a randomized clinical trial. JAMA: Journal of the American Medical Association, 321(1), pp. 56-68. (doi: 10.1001/jama.2018.19802) (PMID:30620371) (PMCID:PMC6583564)

Lee, M. M. Y. , McMurray, J. J.V. , Lorenzo-Almorós, A., Kristensen, S. L., Sattar, N. , Jhund, P. S. and Petrie, M. C. (2019) Diabetic cardiomyopathy. Heart, 105(4), pp. 337-345. (doi: 10.1136/heartjnl-2016-310342) (PMID:30337334)

Ferguson, L. D. , Siebert, S. , McInnes, I. B. and Sattar, N. (2019) Cardiometabolic comorbidities in RA and PsA: lessons learned and future directions. Nature Reviews Rheumatology, 15, pp. 461-474. (doi: 10.1038/s41584-019-0256-0) (PMID:31292564)

Logue, J. , Sattar, N. and Freeman, D. (2019) Obesity. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 419-427. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_39)

Logue, J. , Sattar, N. and Freeman, D. (2019) Obesity. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 419-427. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_39)

2018

Chauhan, A. et al. (2018) Scientific Business Abstracts of the 112th Annual Meeting of the Association of Physicians of Great Britain and Ireland. QJM: An International Journal of Medicine, 111(12), pp. 920-924. (doi: 10.1093/qjmed/hcy193) (PMID:31222346)

Mentz, R. J. et al. (2018) Effects of once-weekly exenatide on clinical outcomes in patients with preexisting cardiovascular disease: prespecified analysis from EXSCEL. Circulation, 138(22), pp. 2576-2578. (doi: 10.1161/CIRCULATIONAHA.118.036811) (PMID:30571356)

Wade, K. H. et al. (2018) Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses. Circulation, 138(20), pp. 2187-2201. (doi: 10.1161/CIRCULATIONAHA.117.033278) (PMID:30524135) (PMCID:PMC6250296)

Ligthart, S. et al. (2018) Genome analyses of >200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders. American Journal of Human Genetics, 103(5), pp. 691-706. (doi: 10.1016/j.ajhg.2018.09.009) (PMID:30388399) (PMCID:PMC6218410)

Anderson, A. S. et al. (2018) Randomised controlled trial to assess the impact of a lifestyle intervention (ActWELL) in women invited to NHS breast screening. BMJ Open, 8(11), e024136. (doi: 10.1136/bmjopen-2018-024136) (PMID:30413516) (PMCID:PMC6231585)

Celis-Morales, C.A. et al. (2018) Associations of dietary protein intake with fat free mass and grip strength: cross-sectional study in 146,816 UK Biobank participants. American Journal of Epidemiology, 187(11), pp. 2405-2414. (doi: 10.1093/aje/kwy134) (PMID:29961893)

Mahajan, A. et al. (2018) Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nature Genetics, 50, pp. 1505-1513. (doi: 10.1038/s41588-018-0241-6) (PMID:30297969)

Sliz, E. et al. (2018) Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment. Circulation, 138(22), pp. 2499-2512. (doi: 10.1161/CIRCULATIONAHA.118.034942) (PMID:30524137)

Wade, K. H., Carslake, D., Sattar, N. , Davey Smith, G. and Timpson, N. J. (2018) BMI and mortality in UK Biobank: revised estimates using Mendelian randomization. Obesity, 26(11), pp. 1796-1806. (doi: 10.1002/oby.22313) (PMID:30358150)

Welsh, P. et al. (2018) Comparison between high-sensitivity cardiac troponin T and cardiac troponin I in a large general population cohort. Clinical Chemistry, 64(11), pp. 1607-1616. (doi: 10.1373/clinchem.2018.292086) (PMID:30126950)

Taylor, R., Adamson, A. J., Sattar, N. , Lean, M. E.J. and Mathers, J. C. (2018) VLCD for weight loss and remission of type 2 diabetes? - Authors' reply. Lancet, 392(10155), p. 1307. (doi: 10.1016/S0140-6736(18)31892-0) (PMID:30322575)

Taylor, R., Al-Mrabeh, A., Zhyzhneuskaya, S., Peters, C., Barnes, A. C., Aribisala, B. S., Hollingsworth, K. G., Mathers, J., Sattar, N. and Lean, M. E.J. (2018) Remission of human type 2 diabetes requires decrease in liver and pancreas fat content but is dependent upon capacity for beta cell recovery. Cell Metabolism, 28, pp. 1-10. (doi: 10.1016/j.cmet.2018.07.003) (PMID:30078554)

Cusi, K., Sattar, N. , García-Pérez, L.-E., Pavo, I., Yu, M., Robertson, K. E., Karanikas, C. A. and Haupt, A. (2018) Dulaglutide decreases plasma aminotransferases in people with type 2 diabetes in a pattern consistent with liver fat reduction: a post hoc analysis of the AWARD programme. Diabetic Medicine, 35(10), pp. 1434-1439. (doi: 10.1111/dme.13697) (PMID:29869810)

Rutter, M. K. and Sattar, N. (2018) Personalised blood pressure ranges in type 2 diabetes? Lancet Diabetes and Endocrinology, 6(10), pp. 761-763. (doi: 10.1016/S2213-8587(18)30002-0) (PMID:29396247)

Sattar, N. , Fitchett, D., Hantel, S., George, J. T. and Zinman, B. (2018) Empagliflozin is associated with improvements in liver enzymes potentially consistent with reductions in liver fat: results from randomised trials including the EMPA-REG OUTCOME® trial. Diabetologia, 61(10), pp. 2155-2163. (doi: 10.1007/s00125-018-4702-3) (PMID:30066148) (PMCID:PMC6133166)

Jenkins, D. A., Bowden, J., Robinson, H. A., Sattar, N. , Loos, R. J.F., Rutter, M. K. and Sperrin, M. (2018) Adiposity-mortality relationships in type 2 diabetes, coronary heart disease and cancer subgroups in the UK Biobank, and their modification by smoking. Diabetes Care, 41(9), pp. 1878-1886. (doi: 10.2337/dc17-2508) (PMID:29970414)

Read, S. H. et al. (2018) Performance of cardiovascular disease risk scores in people diagnosed with type 2 diabetes: external validation using data from the national Scottish diabetes register. Diabetes Care, 41(9), pp. 2010-2018. (doi: 10.2337/dc18-0578) (PMID:30002197)

Williams, B. et al. (2018) 2018 ESC/ESH Guidelines for the management of arterial hypertension. European Heart Journal, 39(33), pp. 3021-3104. (doi: 10.1093/eurheartj/ehy339) (PMID:30165516)

Carberry, J. et al. (2018) Persistent iron within the infarct core after ST-segment elevation myocardial infarction: implications for left ventricular remodeling and health outcomes. JACC: Cardiovascular Imaging, 11(9), pp. 1248-1256. (doi: 10.1016/j.jcmg.2017.08.027) (PMID:29153575) (PMCID:PMC6130225)

Carrick, D. et al. (2018) Hypertension, microvascular pathology and prognosis after an acute myocardial infarction. Hypertension, 72(3), pp. 720-730. (doi: 10.1161/HYPERTENSIONAHA.117.10786) (PMID:30012869) (PMCID:PMC6080885)

van der Laan, S. W. et al. (2018) Genetic susceptibility loci for cardiovascular disease and their impact on atherosclerotic plaques. Circulation: Genomic and Precision Medicine, 11(9), e002115. (doi: 10.1161/CIRCGEN.118.002115)

Rawshani, A. et al. (2018) Risk factors, mortality, and cardiovascular outcomes in patients with type 2 diabetes. New England Journal of Medicine, 379(7), pp. 633-644. (doi: 10.1056/NEJMoa1800256) (PMID:30110583)

Alexander, M. et al. (2018) Real-world data reveal a diagnostic gap in non-alcoholic fatty liver disease. BMC Medicine, 16, 130. (doi: 10.1186/s12916-018-1103-x) (PMID:30099968) (PMCID:PMC6088429)

Rawshani, A., Sattar, N. , Franzén, S., Rawshani, A., Hattersley, A. T., Svensson, A.-M., Eliasson, B. and Gudbjörnsdottir, S. (2018) Excess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study. Lancet, 392(10146), pp. 477-486. (doi: 10.1016/S0140-6736(18)31506-X) (PMID:30129464) (PMCID:PMC6828554)

Bennett-Britton, I., Teyhan, A., Macleod, J., Sattar, N. , Davey Smith, G. and Ben-Shlomo, Y. (2018) Response to: 'On the approach for determining association between changes in marital quality and cardiovascular disease risk factors' by MM Pike. Journal of Epidemiology and Community Health, 72(8), pp. 759-760. (doi: 10.1136/jech-2018-210797) (PMID:29848581)

Bodde, M. C., Welsh, P. , Bergheanu, S. C., Lijfering, W. M., Mertens, B., Liem, A.-H., van der Laarse, A., Sattar, N. and Jukema, J.W. (2018) A rapid (differential) effect of rosuvastatin and atorvastatin on high-sensitivity cardiac Troponin-I in subjects with stable cardiovascular disease. Clinical Pharmacology and Therapeutics, 104(2), pp. 311-316. (doi: 10.1002/cpt.1095) (PMID:29672821)

Muilwijk, M. et al. (2018) Dietary and physical activity recommendations to prevent type 2 diabetes in South Asian adults: a systematic review. PLoS ONE, 13(7), e0200681. (doi: 10.1371/journal.pone.0200681) (PMID:30011314) (PMCID:PMC6047810)

Burgess, S. et al. (2018) Association of LPA variants with risk of coronary disease and the implications for lipoprotein(a)-lowering therapies. JAMA Cardiology, 3(7), pp. 619-627. (doi: 10.1001/jamacardio.2018.1470) (PMID:29926099)

Colombo, M. et al. (2018) Apolipoprotein CIII and N-terminal prohormone b-type natriuretic peptide as independent predictors for cardiovascular disease in type 2 diabetes. Atherosclerosis, 274, pp. 182-190. (doi: 10.1016/j.atherosclerosis.2018.05.014) (PMID:29793175)

Ford, T. J. et al. (2018) Rationale and design of the British Heart Foundation (BHF) Coronary Microvascular Angina (CorMicA) stratified medicine clinical trial. American Heart Journal, 201, pp. 86-94. (doi: 10.1016/j.ahj.2018.03.010) (PMID:29803987) (PMCID:PMC6018570)

Ghouri, N. , Hussain, S., Mohammed, R., Beshyah, S. A., Chowdhury, T. A., Sattar, N. and Sheikh, A. (2018) Diabetes, driving and fasting during Ramadan: the interplay between secular and religious law. BMJ Open Diabetes Research and Care, 6(1), e000520. (doi: 10.1136/bmjdrc-2018-000520) (PMID:29892339) (PMCID:PMC5992469)

Welsh, P. et al. (2018) Circulating amino acids and the risk of macrovascular, microvascular, and mortality outcomes in individuals with type 2 diabetes: results from the ADVANCE trial. Diabetologia, 61(7), pp. 1581-1591. (doi: 10.1007/s00125-018-4619-x) (PMID:29728717) (PMCID:PMC6445481)

West, J., Lawlor, D. A., Santorelli, G., Collings, P., Whincup, P. H., Sattar, N. A. , Farrar, D. and Wright, J. (2018) Associations of social and economic and pregnancy exposures with blood pressure in UK White British and Pakistani children age 4/5. Scientific Reports, 8, 8966. (doi: 10.1038/s41598-018-27316-1) (PMID:29895845) (PMCID:PMC5997744)

Corcoran, D. et al. (2018) Rationale and design of the Coronary Microvascular Angina Cardiac Magnetic Resonance imaging (CorCMR) diagnostic study: the CorMicA CMR sub-study. Open Heart, 5(2), e000924. (doi: 10.1136/openhrt-2018-000924) (PMID:30687508) (PMCID:PMC6326326)

Ginsberg, H. N., Farnier, M., Robinson, J. G., Cannon, C. P., Sattar, N. , Baccara-Dinet, M. T., Letierce, A., Bujas-Bobanovic, M., Louie, M. J. and Colhoun, H. M. (2018) Efficacy and safety of alirocumab in individuals with Diabetes Mellitus: pooled analyses from five placebo-controlled phase 3 studies. Diabetes Therapy, 9(3), pp. 1317-1334. (doi: 10.1007/s13300-018-0439-8) (PMID:29779195) (PMCID:PMC5984942)

Welsh, C. et al. (2018) Association of total and differential leukocyte counts with cardiovascular disease and mortality in the UK Biobank. Arteriosclerosis, Thrombosis, and Vascular Biology, 38(6), pp. 1415-1423. (doi: 10.1161/ATVBAHA.118.310945) (PMID:29699973)

Celis-Morales, C. et al. (2018) Associations of discretionary screen time with mortality, cardiovascular disease and cancer are attenuated by strength, fitness and physical activity: findings from the UK Biobank study. BMC Medicine, 16, 77. (doi: 10.1186/s12916-018-1063-1) (PMID:29792209) (PMCID:PMC5966877)

Celis-Morales, C. A. et al. (2018) Associations of grip strength with cardiovascular, respiratory, and cancer outcomes and all cause mortality: prospective cohort study of half a million UK Biobank participants. British Medical Journal, 361, k1651. (doi: 10.1136/bmj.k1651) (PMID:29739772) (PMCID:PMC5939721)

Iliodromiti, S. et al. (2018) The impact of confounding on the associations of different adiposity measures with the incidence of cardiovascular disease: a cohort study of 296 535 adults of white European descent. European Heart Journal, 39(17), pp. 1514-1520. (doi: 10.1093/eurheartj/ehy057) (PMID:29718151) (PMCID:PMC5930252)

Vaucher, J. et al. (2018) Cannabis use and risk of schizophrenia: a Mendelian randomization study. Molecular Psychiatry, 23(5), pp. 1287-1292. (doi: 10.1038/mp.2016.252) (PMID:28115737) (PMCID:PMC5984096)

Wood, A. M. et al. (2018) Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies. Lancet, 391(10129), pp. 1513-1523. (doi: 10.1016/S0140-6736(18)30134-X) (PMID:29676281)

Botha, S., Forde, L., MacNaughton, S., Shearer, R., Lindsay, R. , Sattar, N. , Morrison, D., Welsh, P. and Logue, J. (2018) The effect of non-surgical weight management on weight and glycaemic control in people with type 2 diabetes: a comparison of interventional and non-interventional outcomes at three years. Diabetes, Obesity and Metabolism, 20(4), pp. 879-888. (doi: 10.1111/dom.13171) (PMID:29178635)

Delles, C. et al. (2018) Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997. European Journal of Heart Failure, 20, pp. 663-673. (doi: 10.1002/ejhf.1076) (PMID:29226610) (PMCID:PMC5947152)

Dennis, J. M. et al. (2018) Precision medicine in type 2 diabetes: clinical markers of insulin resistance are associated with altered short- and long-term glycemic response to DPP-4 inhibitor therapy. Diabetes Care, 41(4), pp. 705-712. (doi: 10.2337/dc17-1827) (PMID:29386249)

Griffin, S. J. et al. (2018) Metformin in non-diabetic hyperglycaemia: the GLINT feasibility RCT. Health Technology Assessment, 22(18), (doi: 10.3310/hta22180) (PMID:29652246)

Mahajan, A. et al. (2018) Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Nature Genetics, 50(4), pp. 559-571. (doi: 10.1038/s41588-018-0084-1) (PMID:29632382)

Malik, R. et al. (2018) Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nature Genetics, 50(4), pp. 524-537. (doi: 10.1038/s41588-018-0058-3) (PMID:29531354) (PMCID:PMC5968830)

von Birgelen, C. et al. (2018) "Silent" diabetes and clinical outcome after treatment with contemporary drug-eluting stents: the BIO-RESORT silent diabetes study. JACC: Cardiovascular Interventions, 11(5), pp. 448-459. (doi: 10.1016/j.jcin.2017.10.038) (PMID:29454724)

Parsons, T. J., Sartini, C., Welsh, P. , Sattar, N. , Ash, S., Lennon, L. T., Wannamethee, S. G., Lee, I.-M., Whincup, P. H. and Jefferis, B. J. (2018) Objectively measured physical activity and cardiac biomarkers: A cross sectional population based study in older men. International Journal of Cardiology, 254, pp. 322-327. (doi: 10.1016/j.ijcard.2017.11.003) (PMID:29407114) (PMCID:PMC5958950)

Edqvist, J., Rawshani, A., Adiels, M., Björck, L., Lind, M., Svensson, A.-M., Gudbjörnsdottir, S., Sattar, N. and Rosengren, A. (2018) BMI and mortality in patients with new-onset type 2 diabetes: a comparison with age- and sex-matched control subjects from the general population. Diabetes Care, 41(3), pp. 458-493. (doi: 10.2337/dc17-1309) (PMID:29298801)

Greene, S. J. et al. (2018) Prevalent and incident heart failure in cardiovascular outcome trials of patients with type 2 diabetes. Journal of the American College of Cardiology, 71(12), pp. 1379-1390. (doi: 10.1016/j.jacc.2018.01.047) (PMID:29534825)

Steinarsson, A. O., Rawshani, A., Gudbjörnsdottir, S., Franzén, S., Svensson, A.-M. and Sattar, N. (2018) Short-term progression of cardiometabolic risk factors in relation to age at type 2 diabetes diagnosis: a longitudinal observational study of 100,606 individuals from the Swedish National Diabetes Register. Diabetologia, 61(3), pp. 599-606. (doi: 10.1007/s00125-017-4532-8) (PMID:29318343) (PMCID:PMC6448968)

Taylor, R. et al. (2018) Clinical and metabolic features of the randomised controlled Diabetes Remission Clinical Trial (DiRECT) cohort. Diabetologia, 61(3), pp. 589-598. (doi: 10.1007/s00125-017-4503-0) (PMID:29188339)

Nelson, S. M. , Haig, C. , McConnachie, A. , Sattar, N. , Ring, S. M., Smith, G. D. , Lawlor, D. A. and Lindsay, R. S. (2018) Maternal thyroid function and child educational attainment: prospective cohort study. British Medical Journal, 360, k452. (doi: 10.1136/bmj.k452) (PMID:29463525) (PMCID:PMC5819484)

Lean, M. E.J. et al. (2018) Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. Lancet, 391(10120), pp. 541-551. (doi: 10.1016/S0140-6736(17)33102-1) (PMID:29221645)

Wang, Q., Ferreira, D. L. S., Nelson, S. M. , Sattar, N. , Ala-Korpela, M. and Lawlor, D. A. (2018) Metabolic characterization of menopause: cross-sectional and longitudinal evidence. BMC Medicine, 16, 17. (doi: 10.1186/s12916-018-1008-8) (PMID:29402284) (PMCID:PMC5800033)

Corcoran, D. et al. (2018) The effects of remote ischaemic preconditioning on coronary artery function in patients with stable coronary artery disease. International Journal of Cardiology, 252, pp. 24-30. (doi: 10.1016/j.ijcard.2017.10.082) (PMID:29249435) (PMCID:PMC5761717)

Anderson, J. J. , Darwis, N. D.M., Mackay, D. F. , Celis-Morales, C. , Lyall, D. M. , Sattar, N. , Gill, J. M.R. and Pell, J. P. (2018) Red and processed meat consumption and breast cancer: UK Biobank cohort study and meta-analysis. European Journal of Cancer, 90, pp. 73-82. (doi: 10.1016/j.ejca.2017.11.022)

Ferguson, L.D. , Ntuk, U.E., Celis-Morales, C. , Mackay, D.F. , Pell, J.P. , Gill, J.M.R. and Sattar, N. (2018) Men across a range of ethnicities have a higher prevalence of diabetes: findings from a cross-sectional study of 500000 UK Biobank participants. Diabetic Medicine, 35(2), pp. 270-276. (doi: 10.1111/dme.13551) (PMID:29171078)

Toth, P. P., Sattar, N. , Blom, D. J., Martin, S. S., Jones, S. R., Monsalvo, M. L., Elliott, M., Davis, M., Somaratne, R. and Preiss, D. (2018) Effect of evolocumab on lipoprotein particles. American Journal of Cardiology, 121(3), pp. 308-314. (doi: 10.1016/j.amjcard.2017.10.028) (PMID:29221604)

Welsh, P. et al. (2018) Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study. European Journal of Heart Failure, 20(2), pp. 268-277. (doi: 10.1002/ejhf.988) (PMID:28960777) (PMCID:PMC6607475)

Wild, S. H. et al. (2018) Cardiovascular disease, cancer, and mortality among people with type 2 diabetes and alcoholic or nonalcoholic fatty liver disease hospital admission. Diabetes Care, 41(2), pp. 341-347. (doi: 10.2337/dc17-1590) (PMID:29167212)

Onyiaodike, C. C. et al. (2018) Pre-conception maternal erythrocyte saturated to unsaturated fatty acid ratio predicts pregnancy after natural cycle frozen embryo transfer. Scientific Reports, 8, 1216. (doi: 10.1038/s41598-018-19500-0) (PMID:29352147) (PMCID:PMC5775249)

Jiang, X. et al. (2018) Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. Nature Communications, 9, 260. (doi: 10.1038/s41467-017-02662-2) (PMID:29343764) (PMCID:PMC5772647)

Gale, C. R. et al. (2018) The epigenetic clock and objectively measured sedentary and walking behavior in older adults: the Lothian Birth Cohort 1936. Clinical Epigenetics, 10, 4. (doi: 10.1186/s13148-017-0438-z) (PMID:29321814) (PMCID:PMC5759300)

Floyd, J.S. et al. (2018) Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group. Pharmacogenomics Journal, 18(1), pp. 127-135. (doi: 10.1038/tpj.2016.90) (PMID:27958378) (PMCID:PMC5468495)

Read, S.H. et al. (2018) Incident ischaemic stroke and Type 2 diabetes: trends in incidence and case fatality in Scotland 2004–2013. Diabetic Medicine, 35(1), pp. 99-106. (doi: 10.1111/dme.13528) (PMID:29044687)

Walker, J., Colhoun, H., Livingstone, S., McCrimmon, R., Petrie, J. , Sattar, N. and Wild, S. (2018) Type 2 diabetes, socioeconomic status and life expectancy in Scotland (2012-2014): a population-based observational study. Diabetologia, 61(1), pp. 108-116. (doi: 10.1007/s00125-017-4478-x) (PMID:29075822) (PMCID:PMC6448945)

West, J., Santorelli, G., Whincup, P. H., Smith, L., Sattar, N. A. , Cameron, N., Farrar, D., Collings, P., Wright, J. and Lawlor, D. A. (2018) Association of maternal exposures with adiposity at age 4/5 years in white British and Pakistani children: findings from the Born in Bradford study. Diabetologia, 61(1), pp. 242-252. (doi: 10.1007/s00125-017-4457-2) (PMID:29064033) (PMCID:PMC6046463)

McAllister, D. A. et al. (2018) Incidence of hospitalisation for heart failure and case-fatality among 3.25 million people with and without diabetes. Circulation, 138(24), pp. 2774-2785. (doi: 10.1161/CIRCULATIONAHA.118.034986) (PMID:29950404) (PMCID:PMC6287897)

Noonan, J. et al. (2018) In vivo multiplex molecular imaging of vascular inflammation using surface-enhanced Raman spectroscopy. Theranostics, 8(22), pp. 6195-6209. (doi: 10.7150/thno.28665) (PMID:30613292) (PMCID:PMC6299693)

2017

Carberry, J. et al. (2017) Persistence of infarct zone T2 hyperintensity at 6 months after acute ST-elevation myocardial infarction: incidence, pathophysiology and prognostic implications. Circulation: Cardiovascular Imaging, 10(12), e006586. (doi: 10.1161/CIRCIMAGING.117.006586) (PMID:29242240) (PMCID:PMC5753833)

Celis-Morales, C. A. et al. (2017) Associations between diabetes and both cardiovascular disease and all-cause mortality are modified by grip strength: evidence from UK Biobank, a prospective population-based cohort study. Diabetes Care, 40(12), pp. 1710-1718. (doi: 10.2337/dc17-0921) (PMID:28986505)

Vieira, M. C. et al. (2017) Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study. BMC Medicine, 15, 194. (doi: 10.1186/s12916-017-0956-8) (PMID:29096631) (PMCID:PMC5669007)

Bennett-Britton, I., Teyhan, A., Macleod, J., Sattar, N. , Davey Smith, G. and Ben-Shlomo, Y. (2017) Changes in marital quality over 6 years and its association with cardiovascular disease risk factors in men: findings from the ALSPAC prospective cohort study. Journal of Epidemiology and Community Health, 71(11), pp. 1094-1100. (doi: 10.1136/jech-2017-209178) (PMID:28993473)

Sartini, C., Whincup, P. H., Wannamethee, S. G., Jefferis, B. J., Lennon, L., Lowe, G. D.O., Welsh, P. , Sattar, N. and Morris, R. W. (2017) Associations of time of day with cardiovascular disease risk factors measured in older men: results from the British Regional Heart Study. BMJ Open, 7(11), e018264. (doi: 10.1136/bmjopen-2017-018264) (PMID:29133328) (PMCID:PMC5695475)

Sattar, N. , Toth, P. P., Blom, D. J., Koren, M. J., Soran, H., Uhart, M., Elliott, M., Cyrille, M., Somaratne, R. and Preiss, D. (2017) Effect of the proprotein convertase subtilisin/kexin type 9 inhibitor evolocumab on glycemia, body weight, and new-onset diabetes mellitus. American Journal of Cardiology, 120(9), pp. 1521-1527. (doi: 10.1016/j.amjcard.2017.07.047) (PMID:28844508)

Butler, J. et al. (2017) The potential role and rationale for treatment of heart failure with sodium-glucose co-transporter 2 inhibitors. European Journal of Heart Failure, 19(11), pp. 1390-1400. (doi: 10.1002/ejhf.933) (PMID:28836359)

Holman, R. R. et al. (2017) Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial. Lancet Diabetes and Endocrinology, 5(11), pp. 877-886. (doi: 10.1016/S2213-8587(17)30309-1) (PMID:28917545)

Welsh, P. , Grassia, G., Botha, S., Sattar, N. and Maffia, P. (2017) Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? British Journal of Pharmacology, 174(22), pp. 3898-3913. (doi: 10.1111/bph.13818) (PMID:28409825) (PMCID:PMC5660005)

Joshi, P. K. et al. (2017) Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. Nature Communications, 8, 910. (doi: 10.1038/s41467-017-00934-5) (PMID:29030599) (PMCID:PMC5715013)

Johns, E. and Sattar, N. (2017) Cardiovascular and mortality risks in migrant South Asians with type 2 diabetes: are we winning the battle? Current Diabetes Reports, 17, 100. (doi: 10.1007/s11892-017-0929-5) (PMID:28920146)

Toth, P. P. et al. (2017) Systematic review and network meta-analysis on the efficacy of evolocumab and other therapies for the management of lipid levels in hyperlipidemia. Journal of the American Heart Association, 6(10), e005367. (doi: 10.1161/JAHA.116.005367) (PMID:28971955)

White, S. L., Pasupathy, D., Sattar, N. , Nelson, S. M. , Lawlor, D. A., Briley, A. L., Seed, P. T., Welsh, P. and Poston, L. (2017) Metabolic profiling of gestational diabetes in obese women during pregnancy. Diabetologia, 60(10), pp. 1903-1912. (doi: 10.1007/s00125-017-4380-6) (PMID:28766127)

Zhao, W. et al. (2017) Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. Nature Genetics, 49(10), pp. 1450-1457. (doi: 10.1038/ng.3943) (PMID:28869590)

Robertson, J., Porter, D., Sattar, N. , Packard, C. J. , Caslake, M., McInnes, I. and McCarey, D. (2017) Interleukin-6 blockade raises LDL via reduced catabolism rather than via increased synthesis: a cytokine-specific mechanism for cholesterol changes in rheumatoid arthritis. Annals of the Rheumatic Diseases, 76(11), pp. 1949-1952. (doi: 10.1136/annrheumdis-2017-211708) (PMID:28916714)

McCombie, L., Leslie, W., Taylor, R., Kennon, B., Sattar, N. and Lean, M. E.J. (2017) Beating type 2 diabetes into remission. British Medical Journal, 358, j4030. (doi: 10.1136/bmj.j4030) (PMID:28903916)

Price, A. H., Weir, C. J., Welsh, P. , McLachlan, S., Strachan, M. W.J., Sattar, N. and Price, J. F. (2017) Comparison of non-traditional biomarkers, and combinations of biomarkers, for vascular risk prediction in people with type 2 diabetes: The Edinburgh Type 2 Diabetes Study. Atherosclerosis, 264, pp. 67-73. (doi: 10.1016/j.atherosclerosis.2017.07.009) (PMID:28777936) (PMCID:PMC5603967)

Ridker, P. M. et al. (2017) Antiinflammatory therapy with canakinumab for atherosclerotic disease. New England Journal of Medicine, 377(12), pp. 1119-1131. (doi: 10.1056/NEJMoa1707914) (PMID:28845751)

Rudnicka, A. R., Nightingale, C. M., Donin, A. S., Sattar, N. , Cook, D. G., Whincup, P. H. and Owen, C. G. (2017) Sleep duration and risk of type 2 diabetes. Pediatrics, 140(3), e20170338. (doi: 10.1542/peds.2017-0338) (PMID:28811317)

Wannamethee, S. G., Welsh, P. , Papacosta, O., Ellins, E. A., Halcox, J. P.J., Whincup, P. H. and Sattar, N. (2017) Circulating soluble receptor for advanced glycation end product: cross-sectional associations with cardiac markers and subclinical vascular disease in older men with and without diabetes. Atherosclerosis, 264, pp. 36-43. (doi: 10.1016/j.atherosclerosis.2017.07.008) (PMID:28759844) (PMCID:PMC5603971)

Ferguson, L. D. and Sattar, N. (2017) Impact of obesity on cardiovascular disease. In: Sbraccia, P. and Finer, N. (eds.) Obesity: Pathogenesis, Diagnosis, and Treatment. Series: Endocrinology (4). Springer International Publishing, pp. 1-21. ISBN 9783319476858 (doi: 10.1007/978-3-319-47685-8_25-1)

Januzzi, J. L., Butler, J., Jarolim, P., Sattar, N. , Vijapurkar, U., Desai, M. and Davies, M. J. (2017) Effects of canagliflozin on cardiovascular biomarkers in older adults with type 2 diabetes. Journal of the American College of Cardiology, 70(6), pp. 704-712. (doi: 10.1016/j.jacc.2017.06.016) (PMID:28619659)

Willeit, P. et al. (2017) High-sensitivity cardiac troponin concentration and risk of first-ever cardiovascular outcomes: literature-based meta-analysis involving 154,052 participants. Journal of the American College of Cardiology, 70(5), pp. 558-568. (doi: 10.1016/j.jacc.2017.05.062) (PMID:28750699) (PMCID:PMC5527070)

Jenks, S. J., Conway, B. R., McLachlan, S., Teoh, W. L., Williamson, R. M., Webb, D. J., Welsh, P. , Sattar, N. , Strachan, M. W.J. and Price, J. F. (2017) Cardiovascular disease biomarkers are associated with declining renal function in type 2 diabetes. Diabetologia, 60(8), pp. 1400-1408. (doi: 10.1007/s00125-017-4297-0) (PMID:28528401) (PMCID:PMC5491560)

Lyall, D. M. et al. (2017) Association of body mass index with cardiometabolic disease in the UK Biobank: a Mendelian randomization study. JAMA Cardiology, 2(8), pp. 882-889. (doi: 10.1001/jamacardio.2016.5804) (PMID:28678979) (PMCID:PMC5710596)

Ntuk, U.E., Celis-Morales, C.A. , Mackay, D.F. , Sattar, N. , Pell, J.P. and Gill, J.M.R. (2017) Association between grip strength and diabetes prevalence in black, South Asian, and white European ethnic groups: a cross-sectional study of 418,656 UK Biobank participants. Diabetic Medicine, 34(8), pp. 1120-1128. (doi: 10.1111/dme.13323) (PMID:28144980)

Petrie, J. R. et al. (2017) Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial. Lancet Diabetes and Endocrinology, 5(8), pp. 597-609. (doi: 10.1016/S2213-8587(17)30194-8) (PMID:28615149) (PMCID:PMC5641446)

Ohkuma, T. et al. (2017) Cardiac stress and inflammatory markers as predictors of heart failure in patients with type 2 diabetes: the ADVANCE trial. Diabetes Care, 40(9), pp. 1203-1209. (doi: 10.2337/dc17-0509) (PMID:28684396)

Nightingale, C. M., Rudnicka, A. R., Donin, A. S., Sattar, N. , Cook, D. G., Whincup, P. H. and Owen, C. G. (2017) Screen time is associated with adiposity and insulin resistance in children. Archives of Disease in Childhood, 102(7), pp. 612-616. (doi: 10.1136/archdischild-2016-312016) (PMID:28288985) (PMCID:PMC5519944)

Patel, N. et al. (2017) Infant adiposity following a randomised controlled trial of a behavioural intervention in obese pregnancy. International Journal of Obesity, 41(7), pp. 1018-1026. (doi: 10.1038/ijo.2017.44) (PMID:28216644)

Zewinger, S. et al. (2017) Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study. Lancet Diabetes and Endocrinology, 5(7), pp. 534-543. (doi: 10.1016/S2213-8587(17)30096-7) (PMID:28566218)

Huda, S. S., Jordan, F., Bray, J., Love, G., Payne, R., Sattar, N. and Freeman, D. J. (2017) Visceral adipose tissue activated macrophage content and inflammatory adipokine secretion is higher in pre-eclampsia than in healthy pregnancy. Clinical Science, 131(13), pp. 1529-1540. (doi: 10.1042/CS20160832) (PMID:28566469) (PMCID:PMC6376613)

van den Berg, M. E. et al. (2017) Discovery of novel heart rate-associated loci using the Exome Chip. Human Molecular Genetics, 26(12), pp. 2346-2363. (doi: 10.1093/hmg/ddx113) (PMID:28379579) (PMCID:PMC5458336)

Dale, C. E. et al. (2017) Causal associations of adiposity and body fat distribution with coronary heart disease, stroke subtypes, and type 2 diabetes mellitus: a Mendelian randomization analysis. Circulation, 135(24), pp. 2373-2388. (doi: 10.1161/CIRCULATIONAHA.116.026560) (PMID:28500271) (PMCID:PMC5515354)

Sattar, N. and Preiss, D. (2017) Reverse causality in cardiovascular epidemiological research: more common than imagined? Circulation, 135(24), pp. 2369-2372. (doi: 10.1161/CIRCULATIONAHA.117.028307) (PMID:28606949)