Dr Mark Salji
- Senior Clinical Lecturer, Honorary Clinical Senior Lecturer (School of Cancer Sciences)
Research interests
Research groups
Publications
2023
Taggart, Ruairidh, Dutto, Lorenzo, Leung, Hing Y. ORCID: https://orcid.org/0000-0002-3933-3975, Salji, Mark
ORCID: https://orcid.org/0000-0003-4261-3086 and Ahmad, Imran
ORCID: https://orcid.org/0000-0002-4404-1926
(2023)
A contemporary analysis of disease upstaging of Gleason 3+3 prostate cancer patients after Robot-Assisted Laparoscopic Prostatectomy (RALP).
Cancer Medicine, 12(22),
pp. 20830-20837.
(doi: 10.1002/cam4.6651)
(PMID:3792988)
(PMCID:PMC10709727)
Rushworth, L. K. et al. (2023) Phase II proof of concept study of atorvastatin in castration resistant prostate cancer. BJU International, 131(2), pp. 236-243. (doi: 10.1111/bju.15851) (PMID:35844167) (PMCID:PMC10087532)
2022
Freckmann, E. C. et al. (2022) Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging. Nature Communications, 13, 5317. (doi: 10.1038/s41467-022-32958-x) (PMID:36085324) (PMCID:PMC9463449)
Salji, M. J. et al. (2022) Multi-omics and pathway analysis identify potential roles for tumour n-acetyl aspartate accumulation in murine models of castration resistant prostate cancer. iScience, 25(4), 104056. (doi: 10.1016/j.isci.2022.104056) (PMID:35345457) (PMCID:PMC8957019)
O’Connell, S. P. et al. (2022) A model to detect significant prostate cancer integrating urinary peptide and extracellular vesicle RNA data. Cancers, 14(8), 1995. (doi: 10.3390/cancers14081995) (PMID:35454901) (PMCID:PMC9027643)
Gaba, Fortis, Tipping, William J., Salji, Mark ORCID: https://orcid.org/0000-0003-4261-3086, Faulds, Karen, Graham, Duncan and Leung, Hing Y.
ORCID: https://orcid.org/0000-0002-3933-3975
(2022)
Raman spectroscopy in prostate cancer: techniques, applications and advancements.
Cancers, 14(6),
1535.
(doi: 10.3390/cancers14061535)
(PMID:35326686)
(PMCID:PMC8946151)
Blomme, A. et al. (2022) THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer. EMBO Molecular Medicine, 14(3), e14764. (doi: 10.15252/emmm.202114764) (PMID:35014179) (PMCID:PMC8899912)
Adam, Catherine, Bray, Thomas L., Pérez-López, Ana M., Tan, Ee Hong, Rubio-Ruiz, Belén, Baillache, Daniel J., Houston, Douglas R., Salji, Mark J. ORCID: https://orcid.org/0000-0003-4261-3086, Leung, Hing Y.
ORCID: https://orcid.org/0000-0002-3933-3975 and Unciti-Broceta, Asier
(2022)
A 5-FU precursor designed to evade anabolic and catabolic drug pathways and activated by Pd chemistry in vitro and in vivo.
Journal of Medicinal Chemistry, 65(1),
pp. 552-561.
(doi: 10.1021/acs.jmedchem.1c01733)
(PMID:34979089)
2021
Martinez, R. S. et al. (2021) SLFN5 regulates LAT1-mediated mTOR activation in castration-resistant prostate cancer. Cancer Research, 81(13), pp. 3664-3678. (doi: 10.1158/0008-5472.CAN-20-3694) (PMID:33985973)
Ntala, C. et al. (2021) Analysis of prostate cancer tumor microenvironment identifies reduced stromal CD4 effector T-cell infiltration in tumors with pelvic nodal metastasis. European Urology Open Science, 29, pp. 19-29. (doi: 10.1016/j.euros.2021.05.001) (PMID:34337530) (PMCID:PMC8317840)
Cangiano, M. et al. (2021) Gene regulation network analysis on human prostate orthografts highlights a potential role for the JMJD6 regulon in clinical prostate cancer. Cancers, 13(9), 2094. (doi: 10.3390/cancers13092094) (PMID:33925994) (PMCID:PMC8123677)
2020
Blomme, A. et al. (2020) 2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer. Nature Communications, 11, 2508. (doi: 10.1038/s41467-020-16126-7) (PMID:32427840) (PMCID:PMC7237503)
Loveridge, C. J. et al. (2020) BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration. Oncogene, 39, pp. 1797-1806. (doi: 10.1038/s41388-019-1106-x) (PMID:31740786) (PMCID:PMC7033044)
2018
Salji, Mark ORCID: https://orcid.org/0000-0003-4261-3086, Hendry, Jane, Patel, Amit, Ahmad, Imran
ORCID: https://orcid.org/0000-0002-4404-1926, Nixon, Colin and Leung, Hing Y.
ORCID: https://orcid.org/0000-0002-3933-3975
(2018)
Peri-prostatic fat volume measurement as a predictive tool for castration resistance in advanced prostate cancer.
European Urology Focus, 4(6),
pp. 858-866.
(doi: 10.1016/j.euf.2017.01.019)
(PMID:28753854)
(PMCID:PMC6314965)
Bray, Thomas L., Salji, Mark ORCID: https://orcid.org/0000-0003-4261-3086, Brombin, Alessandro, Pérez-López, Ana M., Rubio-Ruiz, Belén, Galbraith, Laura C.A., Patton, E. Elizabeth, Leung, Hing Y.
ORCID: https://orcid.org/0000-0002-3933-3975 and Unciti-Broceta, Asier
(2018)
Bright insights into palladium-triggered local chemotherapy.
Chemical Science, 9(37),
pp. 7354-7361.
(doi: 10.1039/c8sc02291g)
(PMID:30542538)
(PMCID:PMC6237126)
Patel, R. et al. (2018) Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1. EMBO Molecular Medicine, 10(4), e8347. (doi: 10.15252/emmm.201708347) (PMID:29540470) (PMCID:PMC5887544)
2017
Winchester, Catherine L., Salji, Mark J. ORCID: https://orcid.org/0000-0003-4261-3086 and Kasivisvanathan, Veeru
(2017)
Gathering preliminary data.
Journal of Clinical Urology, 10(6),
pp. 568-572.
(doi: 10.1177/2051415817724713)
Loveridge, C. J. et al. (2017) Analysis of Nkx3.1:Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity. Scientific Reports, 7, 13241. (doi: 10.1038/s41598-017-13346-8) (PMID:29038439) (PMCID:PMC5643304)
2016
Salji, Mark ORCID: https://orcid.org/0000-0003-4261-3086, Ahmad, Imran
ORCID: https://orcid.org/0000-0002-4404-1926 and Winchester, Catherine
(2016)
Non-clinical research – laboratory based.
Journal of Clinical Urology, 9(6),
pp. 362-364.
(doi: 10.1177/2051415816650134)
Winchester, Catherine and Salji, Mark ORCID: https://orcid.org/0000-0003-4261-3086
(2016)
Writing a literature review.
Journal of Clinical Urology, 9(5),
pp. 308-312.
(doi: 10.1177/2051415816650133)
Ahmad, I. et al. (2016) Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer. Proceedings of the National Academy of Sciences of the United States of America, 113(29), pp. 8290-8295. (doi: 10.1073/pnas.1601571113) (PMID:27357679) (PMCID:PMC4961202)
Articles
Taggart, Ruairidh, Dutto, Lorenzo, Leung, Hing Y. ORCID: https://orcid.org/0000-0002-3933-3975, Salji, Mark
ORCID: https://orcid.org/0000-0003-4261-3086 and Ahmad, Imran
ORCID: https://orcid.org/0000-0002-4404-1926
(2023)
A contemporary analysis of disease upstaging of Gleason 3+3 prostate cancer patients after Robot-Assisted Laparoscopic Prostatectomy (RALP).
Cancer Medicine, 12(22),
pp. 20830-20837.
(doi: 10.1002/cam4.6651)
(PMID:3792988)
(PMCID:PMC10709727)
Rushworth, L. K. et al. (2023) Phase II proof of concept study of atorvastatin in castration resistant prostate cancer. BJU International, 131(2), pp. 236-243. (doi: 10.1111/bju.15851) (PMID:35844167) (PMCID:PMC10087532)
Freckmann, E. C. et al. (2022) Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging. Nature Communications, 13, 5317. (doi: 10.1038/s41467-022-32958-x) (PMID:36085324) (PMCID:PMC9463449)
Salji, M. J. et al. (2022) Multi-omics and pathway analysis identify potential roles for tumour n-acetyl aspartate accumulation in murine models of castration resistant prostate cancer. iScience, 25(4), 104056. (doi: 10.1016/j.isci.2022.104056) (PMID:35345457) (PMCID:PMC8957019)
O’Connell, S. P. et al. (2022) A model to detect significant prostate cancer integrating urinary peptide and extracellular vesicle RNA data. Cancers, 14(8), 1995. (doi: 10.3390/cancers14081995) (PMID:35454901) (PMCID:PMC9027643)
Gaba, Fortis, Tipping, William J., Salji, Mark ORCID: https://orcid.org/0000-0003-4261-3086, Faulds, Karen, Graham, Duncan and Leung, Hing Y.
ORCID: https://orcid.org/0000-0002-3933-3975
(2022)
Raman spectroscopy in prostate cancer: techniques, applications and advancements.
Cancers, 14(6),
1535.
(doi: 10.3390/cancers14061535)
(PMID:35326686)
(PMCID:PMC8946151)
Blomme, A. et al. (2022) THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer. EMBO Molecular Medicine, 14(3), e14764. (doi: 10.15252/emmm.202114764) (PMID:35014179) (PMCID:PMC8899912)
Adam, Catherine, Bray, Thomas L., Pérez-López, Ana M., Tan, Ee Hong, Rubio-Ruiz, Belén, Baillache, Daniel J., Houston, Douglas R., Salji, Mark J. ORCID: https://orcid.org/0000-0003-4261-3086, Leung, Hing Y.
ORCID: https://orcid.org/0000-0002-3933-3975 and Unciti-Broceta, Asier
(2022)
A 5-FU precursor designed to evade anabolic and catabolic drug pathways and activated by Pd chemistry in vitro and in vivo.
Journal of Medicinal Chemistry, 65(1),
pp. 552-561.
(doi: 10.1021/acs.jmedchem.1c01733)
(PMID:34979089)
Martinez, R. S. et al. (2021) SLFN5 regulates LAT1-mediated mTOR activation in castration-resistant prostate cancer. Cancer Research, 81(13), pp. 3664-3678. (doi: 10.1158/0008-5472.CAN-20-3694) (PMID:33985973)
Ntala, C. et al. (2021) Analysis of prostate cancer tumor microenvironment identifies reduced stromal CD4 effector T-cell infiltration in tumors with pelvic nodal metastasis. European Urology Open Science, 29, pp. 19-29. (doi: 10.1016/j.euros.2021.05.001) (PMID:34337530) (PMCID:PMC8317840)
Cangiano, M. et al. (2021) Gene regulation network analysis on human prostate orthografts highlights a potential role for the JMJD6 regulon in clinical prostate cancer. Cancers, 13(9), 2094. (doi: 10.3390/cancers13092094) (PMID:33925994) (PMCID:PMC8123677)
Blomme, A. et al. (2020) 2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer. Nature Communications, 11, 2508. (doi: 10.1038/s41467-020-16126-7) (PMID:32427840) (PMCID:PMC7237503)
Loveridge, C. J. et al. (2020) BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration. Oncogene, 39, pp. 1797-1806. (doi: 10.1038/s41388-019-1106-x) (PMID:31740786) (PMCID:PMC7033044)
Salji, Mark ORCID: https://orcid.org/0000-0003-4261-3086, Hendry, Jane, Patel, Amit, Ahmad, Imran
ORCID: https://orcid.org/0000-0002-4404-1926, Nixon, Colin and Leung, Hing Y.
ORCID: https://orcid.org/0000-0002-3933-3975
(2018)
Peri-prostatic fat volume measurement as a predictive tool for castration resistance in advanced prostate cancer.
European Urology Focus, 4(6),
pp. 858-866.
(doi: 10.1016/j.euf.2017.01.019)
(PMID:28753854)
(PMCID:PMC6314965)
Bray, Thomas L., Salji, Mark ORCID: https://orcid.org/0000-0003-4261-3086, Brombin, Alessandro, Pérez-López, Ana M., Rubio-Ruiz, Belén, Galbraith, Laura C.A., Patton, E. Elizabeth, Leung, Hing Y.
ORCID: https://orcid.org/0000-0002-3933-3975 and Unciti-Broceta, Asier
(2018)
Bright insights into palladium-triggered local chemotherapy.
Chemical Science, 9(37),
pp. 7354-7361.
(doi: 10.1039/c8sc02291g)
(PMID:30542538)
(PMCID:PMC6237126)
Patel, R. et al. (2018) Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1. EMBO Molecular Medicine, 10(4), e8347. (doi: 10.15252/emmm.201708347) (PMID:29540470) (PMCID:PMC5887544)
Winchester, Catherine L., Salji, Mark J. ORCID: https://orcid.org/0000-0003-4261-3086 and Kasivisvanathan, Veeru
(2017)
Gathering preliminary data.
Journal of Clinical Urology, 10(6),
pp. 568-572.
(doi: 10.1177/2051415817724713)
Loveridge, C. J. et al. (2017) Analysis of Nkx3.1:Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity. Scientific Reports, 7, 13241. (doi: 10.1038/s41598-017-13346-8) (PMID:29038439) (PMCID:PMC5643304)
Salji, Mark ORCID: https://orcid.org/0000-0003-4261-3086, Ahmad, Imran
ORCID: https://orcid.org/0000-0002-4404-1926 and Winchester, Catherine
(2016)
Non-clinical research – laboratory based.
Journal of Clinical Urology, 9(6),
pp. 362-364.
(doi: 10.1177/2051415816650134)
Winchester, Catherine and Salji, Mark ORCID: https://orcid.org/0000-0003-4261-3086
(2016)
Writing a literature review.
Journal of Clinical Urology, 9(5),
pp. 308-312.
(doi: 10.1177/2051415816650133)
Ahmad, I. et al. (2016) Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer. Proceedings of the National Academy of Sciences of the United States of America, 113(29), pp. 8290-8295. (doi: 10.1073/pnas.1601571113) (PMID:27357679) (PMCID:PMC4961202)
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- The role of PSMA related metabolites in the progression and treatment of Prostate Cancer
Urology Foundation
2024 - 2025
- N-Acetyl Aspartate in Castration Resistant Prostate Cancer
Prostate Cancer Foundation
2023 - 2026