Dr Kevin Rattigan

  • Research Associate (Paul O'Gorman Leukaemia Research Centre)

email: Kevin.Rattigan@glasgow.ac.uk

Cancer Sciences

Publications

List by: Type | Date

Jump to: 2023 | 2021 | 2020 | 2018
Number of items: 7.

2023

Woodley, K. et al. (2023) Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death. Nature Communications, 14, 2132. (doi: 10.1038/s41467-023-37652-0) (PMID:37059720) (PMCID:PMC10104861)

Rattigan, K., Zarou, M.-M. and Helgason, G. V. (2023) Metabolism in stem cell driven leukaemia: parallels between haematopoiesis and immunity. Blood Cells, Molecules, and Diseases, (doi: 10.1182/blood.2022018258) (PMID:36634302) (In Press)

2021

Ianniciello, A. et al. (2021) ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy. Science Translational Medicine, 13(613), eabd5016. (doi: 10.1126/scitranslmed.abd5016) (PMID:34586834)

2020

Rodgers, L. C., Cole, J., Rattigan, K. M., Barrett, M. P. , Kurian, N., McInnes, I. B. and Goodyear, C. S. (2020) The rheumatoid synovial environment alters fatty acid metabolism in human monocytes and enhances CCL20 secretion. Rheumatology, 59(4), pp. 869-878. (doi: 10.1093/rheumatology/kez378) (PMID:31497857)

2018

Ianniciello, A., Rattigan, K. M. and Helgason, G. V. (2018) The ins and outs of autophagy and metabolism in hematopoietic and leukemic stem cells: food for thought. Frontiers in Cell and Developmental Biology, 6, 120. (doi: 10.3389/fcell.2018.00120) (PMID:30320108) (PMCID:PMC6169402)

Steketee, P. C. et al. (2018) Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei. PLoS Neglected Tropical Diseases, 12(5), e0006450. (doi: 10.1371/journal.pntd.0006450) (PMID:29758036) (PMCID:PMC5976210)

Rattigan, K. M., Pountain, A. W. , Regnault, C., Achcar, F. , Vincent, I. M. , Goodyear, C. S. and Barrett, M. P. (2018) Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli. PLoS ONE, 13(3), e0194126. (doi: 10.1371/journal.pone.0194126) (PMID:29538444) (PMCID:PMC5851634)

This list was generated on Fri Jun 9 19:58:17 2023 BST.
Jump to: Articles
Number of items: 7.

Articles

Woodley, K. et al. (2023) Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death. Nature Communications, 14, 2132. (doi: 10.1038/s41467-023-37652-0) (PMID:37059720) (PMCID:PMC10104861)

Rattigan, K., Zarou, M.-M. and Helgason, G. V. (2023) Metabolism in stem cell driven leukaemia: parallels between haematopoiesis and immunity. Blood Cells, Molecules, and Diseases, (doi: 10.1182/blood.2022018258) (PMID:36634302) (In Press)

Ianniciello, A. et al. (2021) ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy. Science Translational Medicine, 13(613), eabd5016. (doi: 10.1126/scitranslmed.abd5016) (PMID:34586834)

Rodgers, L. C., Cole, J., Rattigan, K. M., Barrett, M. P. , Kurian, N., McInnes, I. B. and Goodyear, C. S. (2020) The rheumatoid synovial environment alters fatty acid metabolism in human monocytes and enhances CCL20 secretion. Rheumatology, 59(4), pp. 869-878. (doi: 10.1093/rheumatology/kez378) (PMID:31497857)

Ianniciello, A., Rattigan, K. M. and Helgason, G. V. (2018) The ins and outs of autophagy and metabolism in hematopoietic and leukemic stem cells: food for thought. Frontiers in Cell and Developmental Biology, 6, 120. (doi: 10.3389/fcell.2018.00120) (PMID:30320108) (PMCID:PMC6169402)

Steketee, P. C. et al. (2018) Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei. PLoS Neglected Tropical Diseases, 12(5), e0006450. (doi: 10.1371/journal.pntd.0006450) (PMID:29758036) (PMCID:PMC5976210)

Rattigan, K. M., Pountain, A. W. , Regnault, C., Achcar, F. , Vincent, I. M. , Goodyear, C. S. and Barrett, M. P. (2018) Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli. PLoS ONE, 13(3), e0194126. (doi: 10.1371/journal.pone.0194126) (PMID:29538444) (PMCID:PMC5851634)

This list was generated on Fri Jun 9 19:58:17 2023 BST.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • MRC IAA: Therapeutic enzyme to exploit tyrosine dependency in leukaemia
    Medical Research Council
    2023 - 2023
     
  • MRC CiC:Therapeutic enzyme to exploit tyrosine dependency in leukaemia
    Medical Research Council
    2023 - 2023
     
  • Validation of a therapeutic enzyme to exploit tyrosine dependency in leukaemia.
    Beatson Cancer Charity
    2023 - 2024
     
  • Development of therapeutic enzyme to targeting tyrosine dependency in leukaemia
    Tenovus Scotland
    2022 - 2023
     
  • Elucidating metabolomics changes in myeloproliferative neoplasms
    Tenovus Scotland
    2019 - 2020