2024

Wiesheu, R. et al. (2024) IL-27 maintains cytotoxic Ly6C+ T cells that arise from immature precursors. EMBO Journal, 43(14), pp. 2878-2907. (doi: 10.1038/s44318-024-00133-1) (PMID:38816652) (PMCID:PMC11251046)

Donnelly, H. et al. (2024) Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells. Nature Communications, 15, 5791. (doi: 10.1038/s41467-024-50054-0) (PMID:38987295) (PMCID:PMC11237034)

Wei, J. et al. (2024) Risk of SARS-CoV-2 reinfection during multiple Omicron variant waves in the UK general population. Nature Communications, 15, 1008. (doi: 10.1038/s41467-024-44973-1) (PMID:38307854) (PMCID:PMC10837445)

2023

Malik, Natasha ORCID: https://orcid.org/0000-0002-1768-3544, Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, Almuhanna, Hassan N.B., Dunn, Karen M., Lees, Jamie, Cassels, Jennifer, Li, Jiatian, Nakagawa, Rinako, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Michie, Alison M. ORCID: https://orcid.org/0000-0002-5404-475X (2023) mTORC1-selective activation of translation elongation promotes disease progression in chronic lymphocytic leukemia. Leukemia, 37, pp. 2414-2425. (doi: 10.1038/s41375-023-02043-3) (PMID:37775560) (PMCID:PMC10681897)

Lees, Jamie, Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, Moles, Michael W. and Michie, Alison M. ORCID: https://orcid.org/0000-0002-5404-475X (2023) The discrete roles of individual FOXO transcription factor family members in B-cell malignancies. Frontiers in Immunology, 14, 1179101. (doi: 10.3389/fimmu.2023.1179101) (PMID:37275916) (PMCID:PMC10233034)

2022

Hay, J. et al. (2022) PKCβ facilitates leukemogenesis in chronic lymphocytic leukaemia by promoting constitutive BCR-mediated signalling. Cancers, 14(23), 6006. (doi: 10.3390/cancers14236006) (PMID:36497487) (PMCID:PMC9735720)

2021

Walker, A. S. et al. (2021) Tracking the emergence of SARS-CoV-2 alpha variant in the United Kingdom. New England Journal of Medicine, 385(27), pp. 2582-2585. (doi: 10.1056/NEJMc2103227) (PMID:34879193) (PMCID:PMC8693687)

Pouwels, K. B. et al. (2021) Effect of Delta variant on viral burden and vaccine effectiveness against new SARS-CoV-2 infections in the UK. Nature Medicine, 27(12), pp. 2127-2135. (doi: 10.1038/s41591-021-01548-7) (PMID:34650248) (PMCID:PMC8674129)

Wei, J. et al. (2021) Antibody responses to SARS-CoV-2 vaccines in 45,965 adults from the general population of the United Kingdom. Nature Microbiology, 6(9), pp. 1140-1149. (doi: 10.1038/s41564-021-00947-3) (PMID:34290390) (PMCID:PMC8294260)

Walker, A. S. et al. (2021) Ct threshold values, a proxy for viral load in community SARS-CoV-2 cases, demonstrate wide variation across populations and over time. eLife, 10, e64683. (doi: 10.7554/elife.64683) (PMID:34250907) (PMCID:PMC8282332)

Conway, D.I. et al. (2021) SARS-CoV-2 positivity in asymptomatic-screened dental patients. Journal of Dental Research, 100(6), pp. 583-590. (doi: 10.1177/00220345211004849) (PMID:33779355) (PMCID:PMC8138329)

Emary, K. R. W. et al. (2021) Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial. Lancet, 397(10282), pp. 1351-1362. (doi: 10.1016/S0140-6736(21)00628-0) (PMID:33798499) (PMCID:PMC8009612)

Pouwels, K. B. et al. (2021) Community prevalence of SARS-CoV-2 in England from April to November, 2020: results from the ONS Coronavirus Infection Survey. Lancet Public Health, 6(1), e30-e38. (doi: 10.1016/s2468-2667(20)30282-6) (PMID:33308423) (PMCID:PMC7786000)

2019

Loyola, L. et al. (2019) Disrupting MLV integrase:BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model. PLoS Pathogens, 15(12), e1008154. (doi: 10.1371/journal.ppat.1008154) (PMID:31815961) (PMCID:PMC6974304)

Malik, Natasha ORCID: https://orcid.org/0000-0002-1768-3544, Dunn, Karen M., Cassels, Jennifer, Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, Estell, Christopher, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Michie, Alison M. ORCID: https://orcid.org/0000-0002-5404-475X (2019) mTORC1 activity is essential for erythropoiesis and B cell lineage commitment. Scientific Reports, 9, 16917. (doi: 10.1038/s41598-019-53141-1) (PMID:31729420) (PMCID:PMC6858379)

Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, Moles, Michael W., Cassels, Jennifer and Michie, Alison M. ORCID: https://orcid.org/0000-0002-5404-475X (2019) Subcellular fractionation of primary chronic lymphocytic leukemia cells to monitor nuclear/ cytoplasmic protein trafficking. Journal of Visualized Experiments(152), e60426. (doi: 10.3791/60426) (PMID:31710039)

Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, Gilroy, Kathryn, Huser, Camille ORCID: https://orcid.org/0000-0002-3785-7556, Kilbey, Anna, Mcdonald, Alma, MacCallum, Amanda, Holroyd, Ailsa ORCID: https://orcid.org/0000-0001-8687-5286, Cameron, Ewan ORCID: https://orcid.org/0000-0001-8311-1491 and Neil, James C. ORCID: https://orcid.org/0000-0003-4447-8279 (2019) Collaboration of MYC and RUNX2 in lymphoma simulates T‐cell receptor signaling and attenuates p53 pathway activity. Journal of Cellular Biochemistry, 120(10), pp. 18332-18345. (doi: 10.1002/jcb.29143) (PMID:31257681) (PMCID:PMC6772115)

Cosimo, E. et al. (2019) AKT/mTORC2 inhibition activates FOXO1 function in CLL cells reducing B cell receptor-mediated survival. Clinical Cancer Research, 25(5), pp. 1574-1587. (doi: 10.1158/1078-0432.CCR-18-2036) (PMID:30559170) (PMCID:PMC6398589)

2018

Anderson, G. et al. (2018) RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins. Journal of Cellular Biochemistry, 119(3), pp. 2750-2762. (doi: 10.1002/jcb.26443) (PMID:29052866) (PMCID:PMC5813226)

2017

Hay, Jodie F. ORCID: https://orcid.org/0000-0002-2000-2578, Lappin, Katrina, Liberante, Fabio, Kettyle, Laura M., Matchett, Kyle B., Thompson, Alexander and Mills, Ken I. (2017) Integrated analysis of the molecular action of Vorinostat identifies epi-sensitised targets for combination therapy. Oncotarget, 8(40), pp. 67891-67903. (doi: 10.18632/oncotarget.18910) (PMID:28723639) (PMCID:PMC5620222)

Neil, James C. ORCID: https://orcid.org/0000-0003-4447-8279, Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578 and Borland, Gillian (2017) RUNX oncoproteins and miRNA networks. Oncotarget, 8(38), pp. 62818-62819. (doi: 10.18632/oncotarget.20673) (PMID:28968950) (PMCID:PMC5609882)

Neil, James C. ORCID: https://orcid.org/0000-0003-4447-8279, Gilroy, Kathryn, Borland, Gillian, Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, Terry, Anne and Kilbey, Anna (2017) The RUNX genes as conditional oncogenes: insights from retroviral targeting and mouse models. In: Groner, Yoram, Ito, Yoshiaki, Liu, Paul, Neil, James C., Speck, Nancy A. and van Wijnen, Andre (eds.) RUNX Proteins in Development and Cancer. Series: Advances in experimental medicine and biology (962). Springer, pp. 247-264. ISBN 9789811032318 (doi: 10.1007/978-981-10-3233-2_16)

2016

Borland, G. et al. (2016) Addiction to Runx1 is partially attenuated by loss of p53 in the Eμ-Myc lymphoma model. Oncotarget, 7(17), pp. 22973-22987. (doi: 10.18632/oncotarget.8554) (PMID:27056890) (PMCID:PMC5029604)

2013

McLornan, Donal, Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, McLaughlin, Kirsty, Holohan, Caitriona, Burnett, Alan K., Hills, Robert K., Johnston, Patrick G., Mills, Ken I., McMullin, Mary Frances and Longley, Daniel B. (2013) Prognostic and therapeutic relevance of c-FLIP in acute myeloid leukaemia. British Journal of Haematology, 160(2), pp. 188-198. (doi: 10.1111/bjh.12108) (PMID:23167276)

Articles

Wiesheu, R. et al. (2024) IL-27 maintains cytotoxic Ly6C+ T cells that arise from immature precursors. EMBO Journal, 43(14), pp. 2878-2907. (doi: 10.1038/s44318-024-00133-1) (PMID:38816652) (PMCID:PMC11251046)

Donnelly, H. et al. (2024) Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells. Nature Communications, 15, 5791. (doi: 10.1038/s41467-024-50054-0) (PMID:38987295) (PMCID:PMC11237034)

Wei, J. et al. (2024) Risk of SARS-CoV-2 reinfection during multiple Omicron variant waves in the UK general population. Nature Communications, 15, 1008. (doi: 10.1038/s41467-024-44973-1) (PMID:38307854) (PMCID:PMC10837445)

Malik, Natasha ORCID: https://orcid.org/0000-0002-1768-3544, Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, Almuhanna, Hassan N.B., Dunn, Karen M., Lees, Jamie, Cassels, Jennifer, Li, Jiatian, Nakagawa, Rinako, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Michie, Alison M. ORCID: https://orcid.org/0000-0002-5404-475X (2023) mTORC1-selective activation of translation elongation promotes disease progression in chronic lymphocytic leukemia. Leukemia, 37, pp. 2414-2425. (doi: 10.1038/s41375-023-02043-3) (PMID:37775560) (PMCID:PMC10681897)

Lees, Jamie, Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, Moles, Michael W. and Michie, Alison M. ORCID: https://orcid.org/0000-0002-5404-475X (2023) The discrete roles of individual FOXO transcription factor family members in B-cell malignancies. Frontiers in Immunology, 14, 1179101. (doi: 10.3389/fimmu.2023.1179101) (PMID:37275916) (PMCID:PMC10233034)

Hay, J. et al. (2022) PKCβ facilitates leukemogenesis in chronic lymphocytic leukaemia by promoting constitutive BCR-mediated signalling. Cancers, 14(23), 6006. (doi: 10.3390/cancers14236006) (PMID:36497487) (PMCID:PMC9735720)

Walker, A. S. et al. (2021) Tracking the emergence of SARS-CoV-2 alpha variant in the United Kingdom. New England Journal of Medicine, 385(27), pp. 2582-2585. (doi: 10.1056/NEJMc2103227) (PMID:34879193) (PMCID:PMC8693687)

Pouwels, K. B. et al. (2021) Effect of Delta variant on viral burden and vaccine effectiveness against new SARS-CoV-2 infections in the UK. Nature Medicine, 27(12), pp. 2127-2135. (doi: 10.1038/s41591-021-01548-7) (PMID:34650248) (PMCID:PMC8674129)

Wei, J. et al. (2021) Antibody responses to SARS-CoV-2 vaccines in 45,965 adults from the general population of the United Kingdom. Nature Microbiology, 6(9), pp. 1140-1149. (doi: 10.1038/s41564-021-00947-3) (PMID:34290390) (PMCID:PMC8294260)

Walker, A. S. et al. (2021) Ct threshold values, a proxy for viral load in community SARS-CoV-2 cases, demonstrate wide variation across populations and over time. eLife, 10, e64683. (doi: 10.7554/elife.64683) (PMID:34250907) (PMCID:PMC8282332)

Conway, D.I. et al. (2021) SARS-CoV-2 positivity in asymptomatic-screened dental patients. Journal of Dental Research, 100(6), pp. 583-590. (doi: 10.1177/00220345211004849) (PMID:33779355) (PMCID:PMC8138329)

Emary, K. R. W. et al. (2021) Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial. Lancet, 397(10282), pp. 1351-1362. (doi: 10.1016/S0140-6736(21)00628-0) (PMID:33798499) (PMCID:PMC8009612)

Pouwels, K. B. et al. (2021) Community prevalence of SARS-CoV-2 in England from April to November, 2020: results from the ONS Coronavirus Infection Survey. Lancet Public Health, 6(1), e30-e38. (doi: 10.1016/s2468-2667(20)30282-6) (PMID:33308423) (PMCID:PMC7786000)

Loyola, L. et al. (2019) Disrupting MLV integrase:BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model. PLoS Pathogens, 15(12), e1008154. (doi: 10.1371/journal.ppat.1008154) (PMID:31815961) (PMCID:PMC6974304)

Malik, Natasha ORCID: https://orcid.org/0000-0002-1768-3544, Dunn, Karen M., Cassels, Jennifer, Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, Estell, Christopher, Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Michie, Alison M. ORCID: https://orcid.org/0000-0002-5404-475X (2019) mTORC1 activity is essential for erythropoiesis and B cell lineage commitment. Scientific Reports, 9, 16917. (doi: 10.1038/s41598-019-53141-1) (PMID:31729420) (PMCID:PMC6858379)

Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, Moles, Michael W., Cassels, Jennifer and Michie, Alison M. ORCID: https://orcid.org/0000-0002-5404-475X (2019) Subcellular fractionation of primary chronic lymphocytic leukemia cells to monitor nuclear/ cytoplasmic protein trafficking. Journal of Visualized Experiments(152), e60426. (doi: 10.3791/60426) (PMID:31710039)

Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, Gilroy, Kathryn, Huser, Camille ORCID: https://orcid.org/0000-0002-3785-7556, Kilbey, Anna, Mcdonald, Alma, MacCallum, Amanda, Holroyd, Ailsa ORCID: https://orcid.org/0000-0001-8687-5286, Cameron, Ewan ORCID: https://orcid.org/0000-0001-8311-1491 and Neil, James C. ORCID: https://orcid.org/0000-0003-4447-8279 (2019) Collaboration of MYC and RUNX2 in lymphoma simulates T‐cell receptor signaling and attenuates p53 pathway activity. Journal of Cellular Biochemistry, 120(10), pp. 18332-18345. (doi: 10.1002/jcb.29143) (PMID:31257681) (PMCID:PMC6772115)

Cosimo, E. et al. (2019) AKT/mTORC2 inhibition activates FOXO1 function in CLL cells reducing B cell receptor-mediated survival. Clinical Cancer Research, 25(5), pp. 1574-1587. (doi: 10.1158/1078-0432.CCR-18-2036) (PMID:30559170) (PMCID:PMC6398589)

Anderson, G. et al. (2018) RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins. Journal of Cellular Biochemistry, 119(3), pp. 2750-2762. (doi: 10.1002/jcb.26443) (PMID:29052866) (PMCID:PMC5813226)

Hay, Jodie F. ORCID: https://orcid.org/0000-0002-2000-2578, Lappin, Katrina, Liberante, Fabio, Kettyle, Laura M., Matchett, Kyle B., Thompson, Alexander and Mills, Ken I. (2017) Integrated analysis of the molecular action of Vorinostat identifies epi-sensitised targets for combination therapy. Oncotarget, 8(40), pp. 67891-67903. (doi: 10.18632/oncotarget.18910) (PMID:28723639) (PMCID:PMC5620222)

Neil, James C. ORCID: https://orcid.org/0000-0003-4447-8279, Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578 and Borland, Gillian (2017) RUNX oncoproteins and miRNA networks. Oncotarget, 8(38), pp. 62818-62819. (doi: 10.18632/oncotarget.20673) (PMID:28968950) (PMCID:PMC5609882)

Borland, G. et al. (2016) Addiction to Runx1 is partially attenuated by loss of p53 in the Eμ-Myc lymphoma model. Oncotarget, 7(17), pp. 22973-22987. (doi: 10.18632/oncotarget.8554) (PMID:27056890) (PMCID:PMC5029604)

McLornan, Donal, Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, McLaughlin, Kirsty, Holohan, Caitriona, Burnett, Alan K., Hills, Robert K., Johnston, Patrick G., Mills, Ken I., McMullin, Mary Frances and Longley, Daniel B. (2013) Prognostic and therapeutic relevance of c-FLIP in acute myeloid leukaemia. British Journal of Haematology, 160(2), pp. 188-198. (doi: 10.1111/bjh.12108) (PMID:23167276)

Book Sections

Neil, James C. ORCID: https://orcid.org/0000-0003-4447-8279, Gilroy, Kathryn, Borland, Gillian, Hay, Jodie ORCID: https://orcid.org/0000-0002-2000-2578, Terry, Anne and Kilbey, Anna (2017) The RUNX genes as conditional oncogenes: insights from retroviral targeting and mouse models. In: Groner, Yoram, Ito, Yoshiaki, Liu, Paul, Neil, James C., Speck, Nancy A. and van Wijnen, Andre (eds.) RUNX Proteins in Development and Cancer. Series: Advances in experimental medicine and biology (962). Springer, pp. 247-264. ISBN 9789811032318 (doi: 10.1007/978-981-10-3233-2_16)