2023

Derby, S. et al. (2023) Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalisation via macropinocytosis. Neuro-Oncology, (doi: 10.1093/neuonc/noad210) (Accepted for Publication)

Koessinger, D. et al. (2023) Glioblastoma extracellular vesicles influence glial cell hyaluronic acid deposition to promote invasiveness. Neuro-Oncology Advances, 5(1), vdad067. (doi: 10.1093/noajnl/vdad067) (PMID:37334166) (PMCID:PMC10276538)

2021

Al-mubarak, H., Vallatos, A. , Gallagher, L., Birch, J., Chalmers, A.J. and Holmes, W.M. (2021) Evaluating potential of multi-parametric MRI using co-registered histology: Application to a mouse model of glioblastoma. Magnetic resonance imaging, 85, pp. 121-127. (doi: 10.1016/j.mri.2021.10.030) (PMID:34687852)

2019

Al-Mubarak, H., Vallatos, A. , Gallagher, L., Birch, J., Gilmour, L., Foster, J., Chalmers, A.J. and Holmes, W.M. (2019) Stacked in-plane histology for quantitative validation of non-invasive imaging biomarkers: application to an infiltrative brain tumour model. Journal of Neuroscience Methods, 326, 108372. (doi: 10.1016/j.jneumeth.2019.108372) (PMID:31348965)

Vallatos, A. , Al-Mubarak, H.F.I., Birch, J.L., Gallagher, L., Mullin, J.M., Gilmour, L., Holmes, W.M. and Chalmers, A.J. (2019) Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region. Journal of Magnetic Resonance Imaging, 50(2), pp. 529-540. (doi: 10.1002/jmri.26580) (PMID:30569620)

2018

Birch, J. L. et al. (2018) A novel small-molecule inhibitor of MRCK prevents radiation-driven invasion in glioblastoma. Cancer Research, 78(22), pp. 6509-6522. (doi: 10.1158/0008-5472.CAN-18-1697) (PMID:30279244)

2016

Birch, J. et al. (2016) The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma. Biology Open, 5(10), pp. 1371-1379. (doi: 10.1242/bio.019075) (PMID:27543055) (PMCID:PMC5087684)

Clarke, C. J. et al. (2016) The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis. Current Biology, 26(6), pp. 755-765. (doi: 10.1016/j.cub.2016.01.045) (PMID:26948875) (PMCID:PMC4819511)

2012

Harwood, A. J., Nuñez-Corcuera, B., Birch, J. L., Yamada, Y. and Williams, J. G. (2012) Transcriptional repression by a bZIP protein regulates Dictyostelium prespore differentiation. PLoS ONE, 7(1), e29895. (doi: 10.1371/journal.pone.0029895) (PMID:22253818) (PMCID:PMC3253789)

2011

Nunez-Corcuera, B., Birch, J. and Williams, J. G. (2011) A SET/MYND chromatin re-modelling protein regulates Dictyostelium prespore patterning. International Journal of Developmental Biology, 55(2), pp. 205-208. (doi: 10.1387/ijdb.113309bn) (PMID:21671223) (PMCID:PMC3586672)

2010

Barski, A., Chepelev, I., Liko, D., Cuddapah, S., Fleming, A., Birch, J., Cui, K., White, R.J. and Zhao, K. (2010) Pol II and its associated epigenetic marks are present at Pol III–transcribed noncoding RNA genes. Nature Structural and Molecular Biology, 17(5), pp. 629-634. (doi: 10.1038/nsmb.1806) (PMID:20418881) (PMCID:PMC2917008)

Kantidakis, T., Ramsbottom, B. A., Birch, J. L., Dowding, S. N. and White, R. J. (2010) mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1. Proceedings of the National Academy of Sciences of the United States of America, 107(26), pp. 11823-11828. (doi: 10.1073/pnas.1005188107) (PMID:20543138) (PMCID:PMC2900655)

2009

Birch, J. L., Tan, B. C.-M., Panov, K. I., Panova, T. B., Andersen, J. S., Owen-Hughes, T. A., Russell, J., Lee, S.-C. and Zomerdijk, J. C. B. M. (2009) FACT facilitates chromatin transcription by RNA polymerases I and III. EMBO Journal, 28(7), pp. 854-865. (doi: 10.1038/emboj.2009.33) (PMID:19214185) (PMCID:PMC2647773)

2008

Birch, J. L. and Zomerdijk, J. C. B. M. (2008) Structure and function of ribosomal RNA gene chromatin. Biochemical Society Transactions, 36(4), pp. 619-624. (doi: 10.1042/BST0360619) (PMID:18631128) (PMCID:PMC3858719)

Articles

Derby, S. et al. (2023) Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalisation via macropinocytosis. Neuro-Oncology, (doi: 10.1093/neuonc/noad210) (Accepted for Publication)

Koessinger, D. et al. (2023) Glioblastoma extracellular vesicles influence glial cell hyaluronic acid deposition to promote invasiveness. Neuro-Oncology Advances, 5(1), vdad067. (doi: 10.1093/noajnl/vdad067) (PMID:37334166) (PMCID:PMC10276538)

Al-mubarak, H., Vallatos, A. , Gallagher, L., Birch, J., Chalmers, A.J. and Holmes, W.M. (2021) Evaluating potential of multi-parametric MRI using co-registered histology: Application to a mouse model of glioblastoma. Magnetic resonance imaging, 85, pp. 121-127. (doi: 10.1016/j.mri.2021.10.030) (PMID:34687852)

Al-Mubarak, H., Vallatos, A. , Gallagher, L., Birch, J., Gilmour, L., Foster, J., Chalmers, A.J. and Holmes, W.M. (2019) Stacked in-plane histology for quantitative validation of non-invasive imaging biomarkers: application to an infiltrative brain tumour model. Journal of Neuroscience Methods, 326, 108372. (doi: 10.1016/j.jneumeth.2019.108372) (PMID:31348965)

Vallatos, A. , Al-Mubarak, H.F.I., Birch, J.L., Gallagher, L., Mullin, J.M., Gilmour, L., Holmes, W.M. and Chalmers, A.J. (2019) Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region. Journal of Magnetic Resonance Imaging, 50(2), pp. 529-540. (doi: 10.1002/jmri.26580) (PMID:30569620)

Birch, J. L. et al. (2018) A novel small-molecule inhibitor of MRCK prevents radiation-driven invasion in glioblastoma. Cancer Research, 78(22), pp. 6509-6522. (doi: 10.1158/0008-5472.CAN-18-1697) (PMID:30279244)

Birch, J. et al. (2016) The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma. Biology Open, 5(10), pp. 1371-1379. (doi: 10.1242/bio.019075) (PMID:27543055) (PMCID:PMC5087684)

Clarke, C. J. et al. (2016) The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis. Current Biology, 26(6), pp. 755-765. (doi: 10.1016/j.cub.2016.01.045) (PMID:26948875) (PMCID:PMC4819511)

Harwood, A. J., Nuñez-Corcuera, B., Birch, J. L., Yamada, Y. and Williams, J. G. (2012) Transcriptional repression by a bZIP protein regulates Dictyostelium prespore differentiation. PLoS ONE, 7(1), e29895. (doi: 10.1371/journal.pone.0029895) (PMID:22253818) (PMCID:PMC3253789)

Nunez-Corcuera, B., Birch, J. and Williams, J. G. (2011) A SET/MYND chromatin re-modelling protein regulates Dictyostelium prespore patterning. International Journal of Developmental Biology, 55(2), pp. 205-208. (doi: 10.1387/ijdb.113309bn) (PMID:21671223) (PMCID:PMC3586672)

Barski, A., Chepelev, I., Liko, D., Cuddapah, S., Fleming, A., Birch, J., Cui, K., White, R.J. and Zhao, K. (2010) Pol II and its associated epigenetic marks are present at Pol III–transcribed noncoding RNA genes. Nature Structural and Molecular Biology, 17(5), pp. 629-634. (doi: 10.1038/nsmb.1806) (PMID:20418881) (PMCID:PMC2917008)

Kantidakis, T., Ramsbottom, B. A., Birch, J. L., Dowding, S. N. and White, R. J. (2010) mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1. Proceedings of the National Academy of Sciences of the United States of America, 107(26), pp. 11823-11828. (doi: 10.1073/pnas.1005188107) (PMID:20543138) (PMCID:PMC2900655)

Birch, J. L., Tan, B. C.-M., Panov, K. I., Panova, T. B., Andersen, J. S., Owen-Hughes, T. A., Russell, J., Lee, S.-C. and Zomerdijk, J. C. B. M. (2009) FACT facilitates chromatin transcription by RNA polymerases I and III. EMBO Journal, 28(7), pp. 854-865. (doi: 10.1038/emboj.2009.33) (PMID:19214185) (PMCID:PMC2647773)

Birch, J. L. and Zomerdijk, J. C. B. M. (2008) Structure and function of ribosomal RNA gene chromatin. Biochemical Society Transactions, 36(4), pp. 619-624. (doi: 10.1042/BST0360619) (PMID:18631128) (PMCID:PMC3858719)