Dr Catherine Cloix
- Research Associate (Therapeutic Science Research)
telephone:
01413306283
email:
Catherine.Cloix@glasgow.ac.uk
Research Institute of Cancer Sciences, Beatson Institute for CRUK, Switchback Road, Glasgow, G61 1BD
Publications
2022
Koessinger, A. L. et al. (2022) Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics. Cell Death and Differentiation, 29(10), pp. 2089-2104. (doi: 10.1038/s41418-022-01001-3) (PMID:35473984) (PMCID:PMC9525582)
Cao, K. et al. (2022) Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage. Developmental Cell, 57(10), 1211-1225.e6. (doi: 10.1016/j.devcel.2022.03.019) (PMID:35447090)
2021
Bock, F. J. et al. (2021) Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death. Nature Communications, 12, 6572. (doi: 10.1038/s41467-021-26613-0) (PMID:34772930) (PMCID:PMC8590049)
Campbell, K. J. et al. (2021) Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function. Cell Death and Differentiation, 28(9), pp. 2589-2600. (doi: 10.1038/s41418-021-00773-4) (PMID:33785871) (PMCID:PMC8408186)
2020
Koessinger, A. L., Koessinger, D., Stevenson, K., Cloix, C., Mitchell, L., Nixon, C., Gomez-Roman, N. , Chalmers, A. J. , Norman, J. C. and Tait, S. W.G. (2020) Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts. Scientific Reports, 10, 15361. (doi: 10.1038/s41598-020-72322-x) (PMID:32958777) (PMCID:PMC7506024)
Roca Portoles, A., Blanco, G., Sumpton, D., Cloix, C., Mullin, M., Mackay, G. M., O'Neill, K., Lemgruber Soares, L. , Luo, X. and Tait, S. W.G. (2020) Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition. Cell Death and Disease, 11, 616. (doi: 10.1038/s41419-020-02867-2) (PMID:32792521) (PMCID:PMC7426836)
2018
Riley, J. S. et al. (2018) Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis. EMBO Journal, 37(17), e99238. (doi: 10.15252/embj.201899238) (PMID:30049712) (PMCID:PMC6120664)
Soriano, G., Cloix, C., Heilmann, M., Núñez-Olivera, E., Martínez-Abaigar, J. and Jenkins, G. I. (2018) Evolutionary conservation of structure and function of the UVR8 photoreceptor from the liverwort Marchantia polymorpha and the moss Physcomitrella patens. New Phytologist, 217(1), pp. 151-162. (doi: 10.1111/nph.14767) (PMID:28892172)
2017
Giampazolias, E. et al. (2017) Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nature Cell Biology, 19(9), pp. 1116-1129. (doi: 10.1038/ncb3596) (PMID:28846096) (PMCID:PMC5624512)
Hernandez-Fernaud, J. R. et al. (2017) Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity. Nature Communications, 8, 14206. (doi: 10.1038/ncomms14206) (PMID:28198360) (PMCID:PMC5316871)
2016
Sullivan, S. , Takemiya, A., Kharshiing, E., Cloix, C., Shimazaki, K.-i. and Christie, J. M. (2016) Functional characterisation of Arabidopsis phototropin 1 in the hypocotyl apex. Plant Journal, 88(6), pp. 907-920. (doi: 10.1111/tpj.13313) (PMID:27545835) (PMCID:PMC5215551)
Heilmann, M., Velanis, C. N., Cloix, C., Smith, B. O. , Christie, J. M. and Jenkins, G. I. (2016) Dimer/monomer status and in vivo function of salt-bridge mutants of the plant UV-B photoreceptor UVR8. Plant Journal, 88(1), pp. 71-81. (doi: 10.1111/tpj.13260) (PMID:27385642) (PMCID:PMC5091643)
Clarke, C. J. et al. (2016) The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis. Current Biology, 26(6), pp. 755-765. (doi: 10.1016/j.cub.2016.01.045) (PMID:26948875) (PMCID:PMC4819511)
2015
Ji, H., Wang, Y., Cloix, C., Li, K., Jenkins, G. I. , Wang, S., Shang, Z., Shi, Y., Yang, S. and Li, X. (2015) The arabidopsis RCC1 family protein TCF1 regulates freezing tolerance and cold acclimation through modulating lignin biosynthesis. PLoS Genetics, 11(9), e1005471. (doi: 10.1371/journal.pgen.1005471) (PMID:26393916) (PMCID:PMC4579128)
2012
Cloix, C., Kaiserli, E. , Heilmann, M., Baxter, K.J., Brown, B.A., O'Hara, A., Smith, B.O. , Christie, J.M. and Jenkins, G.I. (2012) C-terminal region of the UV-B photoreceptor UVR8 initiates signaling through interaction with the COP1 protein. Proceedings of the National Academy of Sciences of the United States of America, 109(40), pp. 16366-16370. (doi: 10.1073/pnas.1210898109)
2011
Rizzini, L. et al. (2011) Perception of UV-B by the arabidopsis UVR8 protein. Science, 332(6025), pp. 103-106. (doi: 10.1126/science.1200660) (PMID:21454788)
2009
Favory, J.-J. et al. (2009) Interaction of COP1 and UVR8 regulates UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis. EMBO Journal, 28(5), pp. 591-601. (doi: 10.1038/emboj.2009.4) (PMID:19165148) (PMCID:PMC2657586)
2005
Brown, B. A., Cloix, C., Jiang, G. H., Kaiserli, E. , Herzyk, P., Kliebenstein, D. J. and Jenkins, G. I. (2005) A UV-B-specific signaling component orchestrates plant UV protection. Proceedings of the National Academy of Sciences of the United States of America, 102, pp. 18225-18230. (doi: 10.1073/pnas.0507187102) (PMID:16330762) (PMCID:PMC1312397)
Articles
Koessinger, A. L. et al. (2022) Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics. Cell Death and Differentiation, 29(10), pp. 2089-2104. (doi: 10.1038/s41418-022-01001-3) (PMID:35473984) (PMCID:PMC9525582)
Cao, K. et al. (2022) Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage. Developmental Cell, 57(10), 1211-1225.e6. (doi: 10.1016/j.devcel.2022.03.019) (PMID:35447090)
Bock, F. J. et al. (2021) Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death. Nature Communications, 12, 6572. (doi: 10.1038/s41467-021-26613-0) (PMID:34772930) (PMCID:PMC8590049)
Campbell, K. J. et al. (2021) Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function. Cell Death and Differentiation, 28(9), pp. 2589-2600. (doi: 10.1038/s41418-021-00773-4) (PMID:33785871) (PMCID:PMC8408186)
Koessinger, A. L., Koessinger, D., Stevenson, K., Cloix, C., Mitchell, L., Nixon, C., Gomez-Roman, N. , Chalmers, A. J. , Norman, J. C. and Tait, S. W.G. (2020) Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts. Scientific Reports, 10, 15361. (doi: 10.1038/s41598-020-72322-x) (PMID:32958777) (PMCID:PMC7506024)
Roca Portoles, A., Blanco, G., Sumpton, D., Cloix, C., Mullin, M., Mackay, G. M., O'Neill, K., Lemgruber Soares, L. , Luo, X. and Tait, S. W.G. (2020) Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition. Cell Death and Disease, 11, 616. (doi: 10.1038/s41419-020-02867-2) (PMID:32792521) (PMCID:PMC7426836)
Riley, J. S. et al. (2018) Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis. EMBO Journal, 37(17), e99238. (doi: 10.15252/embj.201899238) (PMID:30049712) (PMCID:PMC6120664)
Soriano, G., Cloix, C., Heilmann, M., Núñez-Olivera, E., Martínez-Abaigar, J. and Jenkins, G. I. (2018) Evolutionary conservation of structure and function of the UVR8 photoreceptor from the liverwort Marchantia polymorpha and the moss Physcomitrella patens. New Phytologist, 217(1), pp. 151-162. (doi: 10.1111/nph.14767) (PMID:28892172)
Giampazolias, E. et al. (2017) Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nature Cell Biology, 19(9), pp. 1116-1129. (doi: 10.1038/ncb3596) (PMID:28846096) (PMCID:PMC5624512)
Hernandez-Fernaud, J. R. et al. (2017) Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity. Nature Communications, 8, 14206. (doi: 10.1038/ncomms14206) (PMID:28198360) (PMCID:PMC5316871)
Sullivan, S. , Takemiya, A., Kharshiing, E., Cloix, C., Shimazaki, K.-i. and Christie, J. M. (2016) Functional characterisation of Arabidopsis phototropin 1 in the hypocotyl apex. Plant Journal, 88(6), pp. 907-920. (doi: 10.1111/tpj.13313) (PMID:27545835) (PMCID:PMC5215551)
Heilmann, M., Velanis, C. N., Cloix, C., Smith, B. O. , Christie, J. M. and Jenkins, G. I. (2016) Dimer/monomer status and in vivo function of salt-bridge mutants of the plant UV-B photoreceptor UVR8. Plant Journal, 88(1), pp. 71-81. (doi: 10.1111/tpj.13260) (PMID:27385642) (PMCID:PMC5091643)
Clarke, C. J. et al. (2016) The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis. Current Biology, 26(6), pp. 755-765. (doi: 10.1016/j.cub.2016.01.045) (PMID:26948875) (PMCID:PMC4819511)
Ji, H., Wang, Y., Cloix, C., Li, K., Jenkins, G. I. , Wang, S., Shang, Z., Shi, Y., Yang, S. and Li, X. (2015) The arabidopsis RCC1 family protein TCF1 regulates freezing tolerance and cold acclimation through modulating lignin biosynthesis. PLoS Genetics, 11(9), e1005471. (doi: 10.1371/journal.pgen.1005471) (PMID:26393916) (PMCID:PMC4579128)
Cloix, C., Kaiserli, E. , Heilmann, M., Baxter, K.J., Brown, B.A., O'Hara, A., Smith, B.O. , Christie, J.M. and Jenkins, G.I. (2012) C-terminal region of the UV-B photoreceptor UVR8 initiates signaling through interaction with the COP1 protein. Proceedings of the National Academy of Sciences of the United States of America, 109(40), pp. 16366-16370. (doi: 10.1073/pnas.1210898109)
Rizzini, L. et al. (2011) Perception of UV-B by the arabidopsis UVR8 protein. Science, 332(6025), pp. 103-106. (doi: 10.1126/science.1200660) (PMID:21454788)
Favory, J.-J. et al. (2009) Interaction of COP1 and UVR8 regulates UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis. EMBO Journal, 28(5), pp. 591-601. (doi: 10.1038/emboj.2009.4) (PMID:19165148) (PMCID:PMC2657586)
Brown, B. A., Cloix, C., Jiang, G. H., Kaiserli, E. , Herzyk, P., Kliebenstein, D. J. and Jenkins, G. I. (2005) A UV-B-specific signaling component orchestrates plant UV protection. Proceedings of the National Academy of Sciences of the United States of America, 102, pp. 18225-18230. (doi: 10.1073/pnas.0507187102) (PMID:16330762) (PMCID:PMC1312397)