Dr Catherine Cloix
- Research Associate (Therapeutic Science Research)
telephone:
01413306283
email:
Catherine.Cloix@glasgow.ac.uk
Research Institute of Cancer Sciences, Beatson Institute for CRUK, Switchback Road, Glasgow, G61 1BD
Publications
2024
Vringer, E. et al. (2024) Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response. EMBO Journal, 43(6), pp. 904-930. (doi: 10.1038/s44318-024-00044-1) (PMID:38337057) (PMCID:PMC10943237)
2023
Victorelli, S. et al. (2023) Apoptotic stress causes mtDNA release during senescence and drives the SASP. Nature, 622(7983), pp. 627-636. (doi: 10.1038/s41586-023-06621-4) (PMID:37821702) (PMCID:PMC10584674)
2022
Koessinger, A. L. et al. (2022) Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics. Cell Death and Differentiation, 29(10), pp. 2089-2104. (doi: 10.1038/s41418-022-01001-3) (PMID:35473984) (PMCID:PMC9525582)
Cao, K. et al. (2022) Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage. Developmental Cell, 57(10), 1211-1225.e6. (doi: 10.1016/j.devcel.2022.03.019) (PMID:35447090) (PMCID:PMC9616799)
2021
Bock, F. J. et al. (2021) Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death. Nature Communications, 12, 6572. (doi: 10.1038/s41467-021-26613-0) (PMID:34772930) (PMCID:PMC8590049)
Campbell, K. J. et al. (2021) Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function. Cell Death and Differentiation, 28(9), pp. 2589-2600. (doi: 10.1038/s41418-021-00773-4) (PMID:33785871) (PMCID:PMC8408186)
Koessinger, A. L. et al. (2021) Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics. bioRxiv, (doi: 10.1101/2021.06.13.448232)
2020
Koessinger, Anna L., Koessinger, Dominik, Stevenson, Katrina, Cloix, Catherine, Mitchell, Louise, Nixon, Colin, Gomez-Roman, Natividad ORCID: https://orcid.org/0000-0002-2325-7517, Chalmers, Anthony J.
ORCID: https://orcid.org/0000-0002-1746-7278, Norman, Jim C.
ORCID: https://orcid.org/0000-0002-0098-3014 and Tait, Stephen W.G.
ORCID: https://orcid.org/0000-0001-7697-132X
(2020)
Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts.
Scientific Reports, 10,
15361.
(doi: 10.1038/s41598-020-72322-x)
(PMID:32958777)
(PMCID:PMC7506024)
Roca Portoles, Alba, Blanco, Giovanny, Sumpton, David, Cloix, Catherine, Mullin, Margaret, Mackay, Gillian M., O'Neill, Katelyn, Lemgruber Soares, Leandro ORCID: https://orcid.org/0000-0003-2832-6806, Luo, Xu and Tait, Stephen W.G.
ORCID: https://orcid.org/0000-0001-7697-132X
(2020)
Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition.
Cell Death and Disease, 11,
616.
(doi: 10.1038/s41419-020-02867-2)
(PMID:32792521)
(PMCID:PMC7426836)
2018
Riley, J. S. et al. (2018) Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis. EMBO Journal, 37(17), e99238. (doi: 10.15252/embj.201899238) (PMID:30049712) (PMCID:PMC6120664)
Soriano, Gonzalo, Cloix, Catherine, Heilmann, Monika, Núñez-Olivera, Encarnación, Martínez-Abaigar, Javier and Jenkins, Gareth I. ORCID: https://orcid.org/0000-0002-1855-4875
(2018)
Evolutionary conservation of structure and function of the UVR8 photoreceptor from the liverwort Marchantia polymorpha and the moss Physcomitrella patens.
New Phytologist, 217(1),
pp. 151-162.
(doi: 10.1111/nph.14767)
(PMID:28892172)
2017
Giampazolias, E. et al. (2017) Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nature Cell Biology, 19(9), pp. 1116-1129. (doi: 10.1038/ncb3596) (PMID:28846096) (PMCID:PMC5624512)
Hernandez-Fernaud, J. R. et al. (2017) Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity. Nature Communications, 8, 14206. (doi: 10.1038/ncomms14206) (PMID:28198360) (PMCID:PMC5316871)
2016
Sullivan, Stuart ORCID: https://orcid.org/0000-0002-1042-7855, Takemiya, Atsushi, Kharshiing, Eros, Cloix, Catherine, Shimazaki, Ken-ichiro and Christie, John M.
ORCID: https://orcid.org/0000-0002-9976-0055
(2016)
Functional characterisation of Arabidopsis phototropin 1 in the hypocotyl apex.
Plant Journal, 88(6),
pp. 907-920.
(doi: 10.1111/tpj.13313)
(PMID:27545835)
(PMCID:PMC5215551)
Heilmann, Monika, Velanis, Christos N., Cloix, Catherine, Smith, Brian O. ORCID: https://orcid.org/0000-0003-3363-4168, Christie, John M.
ORCID: https://orcid.org/0000-0002-9976-0055 and Jenkins, Gareth I.
ORCID: https://orcid.org/0000-0002-1855-4875
(2016)
Dimer/monomer status and in vivo function of salt-bridge mutants of the plant UV-B photoreceptor UVR8.
Plant Journal, 88(1),
pp. 71-81.
(doi: 10.1111/tpj.13260)
(PMID:27385642)
(PMCID:PMC5091643)
Clarke, C. J. et al. (2016) The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis. Current Biology, 26(6), pp. 755-765. (doi: 10.1016/j.cub.2016.01.045) (PMID:26948875) (PMCID:PMC4819511)
2015
Ji, Hongtao, Wang, Youning, Cloix, Catherine, Li, Kexue, Jenkins, Gareth I. ORCID: https://orcid.org/0000-0002-1855-4875, Wang, Shuangfeng, Shang, Zhonglin, Shi, Yiting, Yang, Shuhua and Li, Xia
(2015)
The arabidopsis RCC1 family protein TCF1 regulates freezing tolerance and cold acclimation through modulating lignin biosynthesis.
PLoS Genetics, 11(9),
e1005471.
(doi: 10.1371/journal.pgen.1005471)
(PMID:26393916)
(PMCID:PMC4579128)
2012
Cloix, C., Kaiserli, E. ORCID: https://orcid.org/0000-0003-1517-4591, Heilmann, M., Baxter, K.J.
ORCID: https://orcid.org/0000-0001-8237-9103, Brown, B.A., O'Hara, A., Smith, B.O.
ORCID: https://orcid.org/0000-0003-3363-4168, Christie, J.M.
ORCID: https://orcid.org/0000-0002-9976-0055 and Jenkins, G.I.
ORCID: https://orcid.org/0000-0002-1855-4875
(2012)
C-terminal region of the UV-B photoreceptor UVR8 initiates signaling through interaction with the COP1 protein.
Proceedings of the National Academy of Sciences of the United States of America, 109(40),
pp. 16366-16370.
(doi: 10.1073/pnas.1210898109)
2011
Rizzini, L. et al. (2011) Perception of UV-B by the arabidopsis UVR8 protein. Science, 332(6025), pp. 103-106. (doi: 10.1126/science.1200660) (PMID:21454788)
2009
Favory, J.-J. et al. (2009) Interaction of COP1 and UVR8 regulates UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis. EMBO Journal, 28(5), pp. 591-601. (doi: 10.1038/emboj.2009.4) (PMID:19165148) (PMCID:PMC2657586)
2005
Brown, Bobby A., Cloix, Catherine, Jiang, Guang Huai, Kaiserli, Eirini ORCID: https://orcid.org/0000-0003-1517-4591, Herzyk, Pawel, Kliebenstein, Daniel J. and Jenkins, Gareth I.
(2005)
A UV-B-specific signaling component orchestrates plant UV protection.
Proceedings of the National Academy of Sciences of the United States of America, 102,
pp. 18225-18230.
(doi: 10.1073/pnas.0507187102)
(PMID:16330762)
(PMCID:PMC1312397)
Articles
Vringer, E. et al. (2024) Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response. EMBO Journal, 43(6), pp. 904-930. (doi: 10.1038/s44318-024-00044-1) (PMID:38337057) (PMCID:PMC10943237)
Victorelli, S. et al. (2023) Apoptotic stress causes mtDNA release during senescence and drives the SASP. Nature, 622(7983), pp. 627-636. (doi: 10.1038/s41586-023-06621-4) (PMID:37821702) (PMCID:PMC10584674)
Koessinger, A. L. et al. (2022) Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics. Cell Death and Differentiation, 29(10), pp. 2089-2104. (doi: 10.1038/s41418-022-01001-3) (PMID:35473984) (PMCID:PMC9525582)
Cao, K. et al. (2022) Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage. Developmental Cell, 57(10), 1211-1225.e6. (doi: 10.1016/j.devcel.2022.03.019) (PMID:35447090) (PMCID:PMC9616799)
Bock, F. J. et al. (2021) Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death. Nature Communications, 12, 6572. (doi: 10.1038/s41467-021-26613-0) (PMID:34772930) (PMCID:PMC8590049)
Campbell, K. J. et al. (2021) Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function. Cell Death and Differentiation, 28(9), pp. 2589-2600. (doi: 10.1038/s41418-021-00773-4) (PMID:33785871) (PMCID:PMC8408186)
Koessinger, A. L. et al. (2021) Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics. bioRxiv, (doi: 10.1101/2021.06.13.448232)
Koessinger, Anna L., Koessinger, Dominik, Stevenson, Katrina, Cloix, Catherine, Mitchell, Louise, Nixon, Colin, Gomez-Roman, Natividad ORCID: https://orcid.org/0000-0002-2325-7517, Chalmers, Anthony J.
ORCID: https://orcid.org/0000-0002-1746-7278, Norman, Jim C.
ORCID: https://orcid.org/0000-0002-0098-3014 and Tait, Stephen W.G.
ORCID: https://orcid.org/0000-0001-7697-132X
(2020)
Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts.
Scientific Reports, 10,
15361.
(doi: 10.1038/s41598-020-72322-x)
(PMID:32958777)
(PMCID:PMC7506024)
Roca Portoles, Alba, Blanco, Giovanny, Sumpton, David, Cloix, Catherine, Mullin, Margaret, Mackay, Gillian M., O'Neill, Katelyn, Lemgruber Soares, Leandro ORCID: https://orcid.org/0000-0003-2832-6806, Luo, Xu and Tait, Stephen W.G.
ORCID: https://orcid.org/0000-0001-7697-132X
(2020)
Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition.
Cell Death and Disease, 11,
616.
(doi: 10.1038/s41419-020-02867-2)
(PMID:32792521)
(PMCID:PMC7426836)
Riley, J. S. et al. (2018) Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis. EMBO Journal, 37(17), e99238. (doi: 10.15252/embj.201899238) (PMID:30049712) (PMCID:PMC6120664)
Soriano, Gonzalo, Cloix, Catherine, Heilmann, Monika, Núñez-Olivera, Encarnación, Martínez-Abaigar, Javier and Jenkins, Gareth I. ORCID: https://orcid.org/0000-0002-1855-4875
(2018)
Evolutionary conservation of structure and function of the UVR8 photoreceptor from the liverwort Marchantia polymorpha and the moss Physcomitrella patens.
New Phytologist, 217(1),
pp. 151-162.
(doi: 10.1111/nph.14767)
(PMID:28892172)
Giampazolias, E. et al. (2017) Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nature Cell Biology, 19(9), pp. 1116-1129. (doi: 10.1038/ncb3596) (PMID:28846096) (PMCID:PMC5624512)
Hernandez-Fernaud, J. R. et al. (2017) Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity. Nature Communications, 8, 14206. (doi: 10.1038/ncomms14206) (PMID:28198360) (PMCID:PMC5316871)
Sullivan, Stuart ORCID: https://orcid.org/0000-0002-1042-7855, Takemiya, Atsushi, Kharshiing, Eros, Cloix, Catherine, Shimazaki, Ken-ichiro and Christie, John M.
ORCID: https://orcid.org/0000-0002-9976-0055
(2016)
Functional characterisation of Arabidopsis phototropin 1 in the hypocotyl apex.
Plant Journal, 88(6),
pp. 907-920.
(doi: 10.1111/tpj.13313)
(PMID:27545835)
(PMCID:PMC5215551)
Heilmann, Monika, Velanis, Christos N., Cloix, Catherine, Smith, Brian O. ORCID: https://orcid.org/0000-0003-3363-4168, Christie, John M.
ORCID: https://orcid.org/0000-0002-9976-0055 and Jenkins, Gareth I.
ORCID: https://orcid.org/0000-0002-1855-4875
(2016)
Dimer/monomer status and in vivo function of salt-bridge mutants of the plant UV-B photoreceptor UVR8.
Plant Journal, 88(1),
pp. 71-81.
(doi: 10.1111/tpj.13260)
(PMID:27385642)
(PMCID:PMC5091643)
Clarke, C. J. et al. (2016) The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis. Current Biology, 26(6), pp. 755-765. (doi: 10.1016/j.cub.2016.01.045) (PMID:26948875) (PMCID:PMC4819511)
Ji, Hongtao, Wang, Youning, Cloix, Catherine, Li, Kexue, Jenkins, Gareth I. ORCID: https://orcid.org/0000-0002-1855-4875, Wang, Shuangfeng, Shang, Zhonglin, Shi, Yiting, Yang, Shuhua and Li, Xia
(2015)
The arabidopsis RCC1 family protein TCF1 regulates freezing tolerance and cold acclimation through modulating lignin biosynthesis.
PLoS Genetics, 11(9),
e1005471.
(doi: 10.1371/journal.pgen.1005471)
(PMID:26393916)
(PMCID:PMC4579128)
Cloix, C., Kaiserli, E. ORCID: https://orcid.org/0000-0003-1517-4591, Heilmann, M., Baxter, K.J.
ORCID: https://orcid.org/0000-0001-8237-9103, Brown, B.A., O'Hara, A., Smith, B.O.
ORCID: https://orcid.org/0000-0003-3363-4168, Christie, J.M.
ORCID: https://orcid.org/0000-0002-9976-0055 and Jenkins, G.I.
ORCID: https://orcid.org/0000-0002-1855-4875
(2012)
C-terminal region of the UV-B photoreceptor UVR8 initiates signaling through interaction with the COP1 protein.
Proceedings of the National Academy of Sciences of the United States of America, 109(40),
pp. 16366-16370.
(doi: 10.1073/pnas.1210898109)
Rizzini, L. et al. (2011) Perception of UV-B by the arabidopsis UVR8 protein. Science, 332(6025), pp. 103-106. (doi: 10.1126/science.1200660) (PMID:21454788)
Favory, J.-J. et al. (2009) Interaction of COP1 and UVR8 regulates UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis. EMBO Journal, 28(5), pp. 591-601. (doi: 10.1038/emboj.2009.4) (PMID:19165148) (PMCID:PMC2657586)
Brown, Bobby A., Cloix, Catherine, Jiang, Guang Huai, Kaiserli, Eirini ORCID: https://orcid.org/0000-0003-1517-4591, Herzyk, Pawel, Kliebenstein, Daniel J. and Jenkins, Gareth I.
(2005)
A UV-B-specific signaling component orchestrates plant UV protection.
Proceedings of the National Academy of Sciences of the United States of America, 102,
pp. 18225-18230.
(doi: 10.1073/pnas.0507187102)
(PMID:16330762)
(PMCID:PMC1312397)