Ms Assya Legrini
- Research Associate (Clinical Research Garscube)
Publications
2025
Hatthakarnkul, P. et al. (2025) The characteristic of epithelial-specific phenotypes and immunosuppressive microenvironment in the context of tumour budding in colorectal cancer. bioRxiv, Mar 7. (doi: 10.1101/2025.03.05.641608)
2024
Stankey, C.T. et al. (2024) A disease-associated gene desert directs macrophage inflammation through ETS2. Nature, 630(8016), pp. 447-456. (doi: 10.1038/s41586-024-07501-1) (PMID:38839969)
Pennel, K. A.F. et al. (2024) JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors. Journal of Experimental and Clinical Cancer Research, 43, 64. (doi: 10.1186/s13046-024-02958-4) (PMID:38424636) (PMCID:PMC10905886)
2023
Sykes, R. A. et al. (2023) Vascular mechanisms of post-COVID-19 conditions: rho-kinase is a novel target for therapy. European Heart Journal: Cardiovascular Pharmacotherapy, 9(4), pp. 371-386. (doi: 10.1093/ehjcvp/pvad025) (PMID:37019821) (PMCID:PMC10236521)
Wood, C. S. et al. (2023) Spatially resolved transcriptomics deconvolutes prognostic histological subgroups in patients with colorectal cancer and synchronous liver metastases. Cancer Research, 83(8), pp. 1329-1344. (doi: 10.1158/0008-5472.CAN-22-2794) (PMID:37057593) (PMCID:PMC10102851)
2022
Fisher, N. C. et al. (2022) Biological misinterpretation of transcriptional signatures in tumour samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data. Clinical Cancer Research, 28(18), pp. 4056-4069. (doi: 10.1158/1078-0432.CCR-22-1102) (PMID:35792866) (PMCID:PMC9475248)
Dreyer, Stephan B., Upstill-Goddard, Rosie, Legrini, Assya ORCID: https://orcid.org/0000-0001-5377-3048, Biankin, Andrew V.
ORCID: https://orcid.org/0000-0002-0362-5597, Jamieson, Nigel B.
ORCID: https://orcid.org/0000-0002-9552-4725 and Chang, David K.
ORCID: https://orcid.org/0000-0002-4821-3078
(2022)
Genomic and molecular analyses identify molecular subtypes of pancreatic cancer recurrence.
Gastroenterology, 162(1),
320-324.e4.
(doi: 10.1053/j.gastro.2021.09.022)
(PMID:34534536)
(PMCID:PMC8721486)
Dreyer, S., Upstill-Goddard, R., Legrini, A. ORCID: https://orcid.org/0000-0001-5377-3048, Biankin, A.
ORCID: https://orcid.org/0000-0002-0362-5597, Jamieson, N.
ORCID: https://orcid.org/0000-0002-9552-4725 and Chang, D.
ORCID: https://orcid.org/0000-0002-4821-3078
(2022)
Genomic and Molecular Analyses Identify Molecular Subtypes of Pancreatic Cancer Recurrence.
15th World Congress of the International Hepato-Pancreato-Biliary Association, New York, USA, 30 Mar - 02 Apr 2022.
S44-S45.
(doi: 10.1016/j.hpb.2022.05.086)
Articles
Hatthakarnkul, P. et al. (2025) The characteristic of epithelial-specific phenotypes and immunosuppressive microenvironment in the context of tumour budding in colorectal cancer. bioRxiv, Mar 7. (doi: 10.1101/2025.03.05.641608)
Stankey, C.T. et al. (2024) A disease-associated gene desert directs macrophage inflammation through ETS2. Nature, 630(8016), pp. 447-456. (doi: 10.1038/s41586-024-07501-1) (PMID:38839969)
Pennel, K. A.F. et al. (2024) JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors. Journal of Experimental and Clinical Cancer Research, 43, 64. (doi: 10.1186/s13046-024-02958-4) (PMID:38424636) (PMCID:PMC10905886)
Sykes, R. A. et al. (2023) Vascular mechanisms of post-COVID-19 conditions: rho-kinase is a novel target for therapy. European Heart Journal: Cardiovascular Pharmacotherapy, 9(4), pp. 371-386. (doi: 10.1093/ehjcvp/pvad025) (PMID:37019821) (PMCID:PMC10236521)
Wood, C. S. et al. (2023) Spatially resolved transcriptomics deconvolutes prognostic histological subgroups in patients with colorectal cancer and synchronous liver metastases. Cancer Research, 83(8), pp. 1329-1344. (doi: 10.1158/0008-5472.CAN-22-2794) (PMID:37057593) (PMCID:PMC10102851)
Fisher, N. C. et al. (2022) Biological misinterpretation of transcriptional signatures in tumour samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data. Clinical Cancer Research, 28(18), pp. 4056-4069. (doi: 10.1158/1078-0432.CCR-22-1102) (PMID:35792866) (PMCID:PMC9475248)
Dreyer, Stephan B., Upstill-Goddard, Rosie, Legrini, Assya ORCID: https://orcid.org/0000-0001-5377-3048, Biankin, Andrew V.
ORCID: https://orcid.org/0000-0002-0362-5597, Jamieson, Nigel B.
ORCID: https://orcid.org/0000-0002-9552-4725 and Chang, David K.
ORCID: https://orcid.org/0000-0002-4821-3078
(2022)
Genomic and molecular analyses identify molecular subtypes of pancreatic cancer recurrence.
Gastroenterology, 162(1),
320-324.e4.
(doi: 10.1053/j.gastro.2021.09.022)
(PMID:34534536)
(PMCID:PMC8721486)
Conference or Workshop Item
Dreyer, S., Upstill-Goddard, R., Legrini, A. ORCID: https://orcid.org/0000-0001-5377-3048, Biankin, A.
ORCID: https://orcid.org/0000-0002-0362-5597, Jamieson, N.
ORCID: https://orcid.org/0000-0002-9552-4725 and Chang, D.
ORCID: https://orcid.org/0000-0002-4821-3078
(2022)
Genomic and Molecular Analyses Identify Molecular Subtypes of Pancreatic Cancer Recurrence.
15th World Congress of the International Hepato-Pancreato-Biliary Association, New York, USA, 30 Mar - 02 Apr 2022.
S44-S45.
(doi: 10.1016/j.hpb.2022.05.086)