School of Cancer Sciences

Dr Alexander Raven

  • Research Fellow (Clinical Research Garscube)

Publications

List by: Type | Date

Jump to: 2026 | 2023 | 2021 | 2020
Number of items: 7.

2026

White, M. et al. (2026) MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance. Nature, 650(5102), pp. 748-758. (doi: 10.1038/s41586-025-09916-w) (PMID:41286180) (PMCID:PMC12916511)

Raven, A. et al. (2026) Hepatic zonation determines tumorigenic potential of mutant β-catenin. Nature, 649, pp. 739-748. (doi: 10.1038/s41586-025-09733-1) (PMID:41261129) (PMCID:PMC12804091)

Kanellos, G. et al. (2026) Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation. Nature Genetics, 58, pp. 100-115. (doi: 10.1038/s41588-025-02408-7) (PMID:41413654) (PMCID:PMC12807877)

2023

Vande Voorde, J. et al. (2023) Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target. Nature Metabolism, 5(8), pp. 1303-1318. (doi: 10.1038/s42255-023-00857-0) (PMID:37580540) (PMCID:PMC10447251)

2021

Heino, S. et al. (2021) Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas. Science Advances, 7(47), eabj0512. (doi: 10.1126/sciadv.abj0512) (PMID:34788095) (PMCID:PMC8598008)

Flanagan, D. J. et al. (2021) NOTUM from Apc-mutant cells biases clonal competition to initiate cancer. Nature, 594, pp. 430-435. (doi: 10.1038/s41586-021-03525-z) (PMID:34079124) (PMCID:PMC7615049)

2020

Wilson, D. H. et al. (2020) Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors. Nature Communications, 11, 445. (doi: 10.1038/s41467-020-14283-3) (PMID:31974352) (PMCID:PMC6978415)

This list was generated on Tue Sep 8 15:47:24 2026 BST.
Jump to: Articles
Number of items: 7.

Articles

White, M. et al. (2026) MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance. Nature, 650(5102), pp. 748-758. (doi: 10.1038/s41586-025-09916-w) (PMID:41286180) (PMCID:PMC12916511)

Raven, A. et al. (2026) Hepatic zonation determines tumorigenic potential of mutant β-catenin. Nature, 649, pp. 739-748. (doi: 10.1038/s41586-025-09733-1) (PMID:41261129) (PMCID:PMC12804091)

Kanellos, G. et al. (2026) Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation. Nature Genetics, 58, pp. 100-115. (doi: 10.1038/s41588-025-02408-7) (PMID:41413654) (PMCID:PMC12807877)

Vande Voorde, J. et al. (2023) Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target. Nature Metabolism, 5(8), pp. 1303-1318. (doi: 10.1038/s42255-023-00857-0) (PMID:37580540) (PMCID:PMC10447251)

Heino, S. et al. (2021) Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas. Science Advances, 7(47), eabj0512. (doi: 10.1126/sciadv.abj0512) (PMID:34788095) (PMCID:PMC8598008)

Flanagan, D. J. et al. (2021) NOTUM from Apc-mutant cells biases clonal competition to initiate cancer. Nature, 594, pp. 430-435. (doi: 10.1038/s41586-021-03525-z) (PMID:34079124) (PMCID:PMC7615049)

Wilson, D. H. et al. (2020) Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors. Nature Communications, 11, 445. (doi: 10.1038/s41467-020-14283-3) (PMID:31974352) (PMCID:PMC6978415)

This list was generated on Tue Sep 8 15:47:24 2026 BST.

Prior publications

Article

(2019) Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration Nature Cell Biology Alexander Raven. ISSN 1476-4679 (doi: 10.1038/s41556-019-0402-6)

Rayagiri SS, Ranaldi D, Raven A, Mohamad Azhar NIF, Lefebvre O, Zammit PS, Borycki AG (2018) Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal. Nature communications Europe PubMed Central. (doi: 10.1038/s41467-018-03425-3)

Ferreira-Gonzalez S et al. (2018) Paracrine cellular senescence exacerbates biliary injury and impairs regeneration. Nature communications Europe PubMed Central. (doi: 10.1038/s41467-018-03299-5)

Raven A et al. (2017) Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration. Europe PubMed Central. (doi: 10.1038/nature23015)