2024

Borland, G., Wilkie, S. E., Thomson, J., Wang, Z., Tullett, J. M.A., Alic, N. and Selman, C. (2024) Polr3b heterozygosity in mice induces both beneficial and deleterious effects on health during ageing with no effect on lifespan. Aging Cell, (doi: 10.1111/acel.14141) (PMID:38465473) (Early Online Publication)

2021

Wilkie, S. E., Borland, G., Carter, R. N., Morton, N. M. and Selman, C. (2021) Hydrogen sulfide in ageing, longevity and disease. Biochemical Journal, 478(19), pp. 3485-3504. (doi: 10.1042/BCJ20210517) (PMID:34613340) (PMCID:PMC8589328)

Mulvey, L., Wilkie, S. E., Borland, G., Griffiths, K., Sinclair, A., McGuinness, D., Watson, D. G. and Selman, C. (2021) Strain-specific metabolic responses to long-term caloric restriction in female ILSXISS recombinant inbred mice. Molecular and Cellular Endocrinology, 535, 111376. (doi: 10.1016/j.mce.2021.111376) (PMID:34246728) (PMCID:PMC8417819)

Kulaberoglu, Y., Malik, Y., Borland, G., Selman, C. , Alic, N. and Tullet, J. M.A. (2021) RNA polymerase III, ageing and longevity. Frontiers in Genetics, 12, 705122. (doi: 10.3389/fgene.2021.705122) (PMID:34295356) (PMCID:PMC8290157)

2019

Loyola, L. et al. (2019) Disrupting MLV integrase:BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model. PLoS Pathogens, 15(12), e1008154. (doi: 10.1371/journal.ppat.1008154) (PMID:31815961) (PMCID:PMC6974304)

2018

Anderson, G. et al. (2018) RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins. Journal of Cellular Biochemistry, 119(3), pp. 2750-2762. (doi: 10.1002/jcb.26443) (PMID:29052866) (PMCID:PMC5813226)

2017

Neil, J. C. , Hay, J. and Borland, G. (2017) RUNX oncoproteins and miRNA networks. Oncotarget, 8(38), pp. 62818-62819. (doi: 10.18632/oncotarget.20673) (PMID:28968950) (PMCID:PMC5609882)

Kilbey, A. et al. (2017) Runx1 orchestrates sphingolipid metabolism and glucocorticoid resistance in lymphomagenesis. Journal of Cellular Biochemistry, 118(6), pp. 1432-1441. (doi: 10.1002/jcb.25802) (PMID:27869314) (PMCID:PMC5408393)

Neil, J. C. , Gilroy, K., Borland, G., Hay, J. , Terry, A. and Kilbey, A. (2017) The RUNX genes as conditional oncogenes: insights from retroviral targeting and mouse models. In: Groner, Y., Ito, Y., Liu, P., Neil, J. C., Speck, N. A. and van Wijnen, A. (eds.) RUNX Proteins in Development and Cancer. Series: Advances in experimental medicine and biology (962). Springer, pp. 247-264. ISBN 9789811032318 (doi: 10.1007/978-981-10-3233-2_16)

2016

Neil, J. C. , Borland, G. and Kilbey, A. (2016) Addiction to RUNX in lymphoma. Aging, 8(9), pp. 1832-1833. (doi: 10.18632/aging.101071) (PMID:27688195) (PMCID:PMC5076437)

Borland, G. et al. (2016) Addiction to Runx1 is partially attenuated by loss of p53 in the Eμ-Myc lymphoma model. Oncotarget, 7(17), pp. 22973-22987. (doi: 10.18632/oncotarget.8554) (PMID:27056890) (PMCID:PMC5029604)

2014

Huser, C. A. et al. (2014) Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis. PLoS Genetics, 10(2), e1004167. (doi: 10.1371/journal.pgen.1004167) (PMID:24586197) (PMCID:PMC3937229)

2012

Edkins, A.L., Borland, G., Kelly, S.M. , Cogdell, R.J. , Ozanne, B.W. and Cushley, W. (2012) Analysis of the CD23-αv integrin interaction: a study with model peptides. Biochemical and Biophysical Research Communications, 422(2), pp. 207-212. (doi: 10.1016/j.bbrc.2012.04.076)

Wiejak, J., Dunlop, J. , Gao, S., Borland, G. and Yarwood, S. J. (2012) Extracellular signal-regulated kinase mitogen-activated protein kinase-dependent SOCS-3 gene induction requires c-Jun, signal transducer and activator of transcription 3, and specificity protein 3 transcription factors. Molecular Pharmacology, 81(5), pp. 657-668. (doi: 10.1124/mol.111.076976)

Edkins, A.L., Borland, G., Acharya, M., Cogdell, R.J. , Ozanne, B.W. and Cushley, W. (2012) Differential regulation of monocyte cytokine release by αv and β2 integrins that bind CD23. Immunology, 136(2), pp. 241-251. (doi: 10.1111/j.1365-2567.2012.03576.x)

2010

Kilbey, A., Terry, A., Jenkins, A., Borland, G., Zhang, Q.F., Wakelam, M.J.O., Cameron, E.R. and Neil, J.C. (2010) Runx regulation of sphingolipid metabolism and survival signaling. Cancer Research, 70(14), pp. 5860-5869. (doi: 10.1158/0008-5472.CAN-10-0726)

2009

Borland, G., Bird, R. J., Palmer, T. M. and Yarwood, S. J. (2009) Activation of protein kinase Cα by EPAC1 is required for the ERK- and CCAAT/enhancer-binding protein β-dependent induction of the SOCS-3 gene by cyclic AMP in COS1 cells. Journal of Biological Chemistry, 284(26), pp. 17391-17403. (doi: 10.1074/jbc.M109.015370) (PMID:19423709) (PMCID:PMC2719379)

Borland, G., Smith, B.O. and Yarwood, S.J. (2009) EPAC proteins transduce diverse cellular actions of cAMP. British Journal of Pharmacology, 158(1), pp. 70-86. (doi: 10.1111/j.1476-5381.2008.00087.x)

2008

Yarwood, S.J., Borland, G., Sands, W.A. and Palmer, T.M. (2008) Identification of CCAAT/Enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene. Journal of Biological Chemistry, 283(11), pp. 6843-6853. (doi: 10.1074/jbc.M710342200)

2007

Borland, G., Edkins, A.L., Acharya, M., Matheson, J., White, L.J., Allen, J.M., Bonnefoy, J.-Y., Ozanne, B. W. and Cushley, W. (2007) vbeta5 Integrin Sustains Growth of Human Pre-B Cells through an RGD-independent Interaction with a Basic Domain of the CD23 Protein. Journal of Biological Chemistry, 282(37), pp. 27315-27326. (doi: 10.1074/jbc.M609335200)

Articles

Borland, G., Wilkie, S. E., Thomson, J., Wang, Z., Tullett, J. M.A., Alic, N. and Selman, C. (2024) Polr3b heterozygosity in mice induces both beneficial and deleterious effects on health during ageing with no effect on lifespan. Aging Cell, (doi: 10.1111/acel.14141) (PMID:38465473) (Early Online Publication)

Wilkie, S. E., Borland, G., Carter, R. N., Morton, N. M. and Selman, C. (2021) Hydrogen sulfide in ageing, longevity and disease. Biochemical Journal, 478(19), pp. 3485-3504. (doi: 10.1042/BCJ20210517) (PMID:34613340) (PMCID:PMC8589328)

Mulvey, L., Wilkie, S. E., Borland, G., Griffiths, K., Sinclair, A., McGuinness, D., Watson, D. G. and Selman, C. (2021) Strain-specific metabolic responses to long-term caloric restriction in female ILSXISS recombinant inbred mice. Molecular and Cellular Endocrinology, 535, 111376. (doi: 10.1016/j.mce.2021.111376) (PMID:34246728) (PMCID:PMC8417819)

Kulaberoglu, Y., Malik, Y., Borland, G., Selman, C. , Alic, N. and Tullet, J. M.A. (2021) RNA polymerase III, ageing and longevity. Frontiers in Genetics, 12, 705122. (doi: 10.3389/fgene.2021.705122) (PMID:34295356) (PMCID:PMC8290157)

Loyola, L. et al. (2019) Disrupting MLV integrase:BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model. PLoS Pathogens, 15(12), e1008154. (doi: 10.1371/journal.ppat.1008154) (PMID:31815961) (PMCID:PMC6974304)

Anderson, G. et al. (2018) RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins. Journal of Cellular Biochemistry, 119(3), pp. 2750-2762. (doi: 10.1002/jcb.26443) (PMID:29052866) (PMCID:PMC5813226)

Neil, J. C. , Hay, J. and Borland, G. (2017) RUNX oncoproteins and miRNA networks. Oncotarget, 8(38), pp. 62818-62819. (doi: 10.18632/oncotarget.20673) (PMID:28968950) (PMCID:PMC5609882)

Kilbey, A. et al. (2017) Runx1 orchestrates sphingolipid metabolism and glucocorticoid resistance in lymphomagenesis. Journal of Cellular Biochemistry, 118(6), pp. 1432-1441. (doi: 10.1002/jcb.25802) (PMID:27869314) (PMCID:PMC5408393)

Neil, J. C. , Borland, G. and Kilbey, A. (2016) Addiction to RUNX in lymphoma. Aging, 8(9), pp. 1832-1833. (doi: 10.18632/aging.101071) (PMID:27688195) (PMCID:PMC5076437)

Borland, G. et al. (2016) Addiction to Runx1 is partially attenuated by loss of p53 in the Eμ-Myc lymphoma model. Oncotarget, 7(17), pp. 22973-22987. (doi: 10.18632/oncotarget.8554) (PMID:27056890) (PMCID:PMC5029604)

Huser, C. A. et al. (2014) Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis. PLoS Genetics, 10(2), e1004167. (doi: 10.1371/journal.pgen.1004167) (PMID:24586197) (PMCID:PMC3937229)

Edkins, A.L., Borland, G., Kelly, S.M. , Cogdell, R.J. , Ozanne, B.W. and Cushley, W. (2012) Analysis of the CD23-αv integrin interaction: a study with model peptides. Biochemical and Biophysical Research Communications, 422(2), pp. 207-212. (doi: 10.1016/j.bbrc.2012.04.076)

Wiejak, J., Dunlop, J. , Gao, S., Borland, G. and Yarwood, S. J. (2012) Extracellular signal-regulated kinase mitogen-activated protein kinase-dependent SOCS-3 gene induction requires c-Jun, signal transducer and activator of transcription 3, and specificity protein 3 transcription factors. Molecular Pharmacology, 81(5), pp. 657-668. (doi: 10.1124/mol.111.076976)

Edkins, A.L., Borland, G., Acharya, M., Cogdell, R.J. , Ozanne, B.W. and Cushley, W. (2012) Differential regulation of monocyte cytokine release by αv and β2 integrins that bind CD23. Immunology, 136(2), pp. 241-251. (doi: 10.1111/j.1365-2567.2012.03576.x)

Kilbey, A., Terry, A., Jenkins, A., Borland, G., Zhang, Q.F., Wakelam, M.J.O., Cameron, E.R. and Neil, J.C. (2010) Runx regulation of sphingolipid metabolism and survival signaling. Cancer Research, 70(14), pp. 5860-5869. (doi: 10.1158/0008-5472.CAN-10-0726)

Borland, G., Bird, R. J., Palmer, T. M. and Yarwood, S. J. (2009) Activation of protein kinase Cα by EPAC1 is required for the ERK- and CCAAT/enhancer-binding protein β-dependent induction of the SOCS-3 gene by cyclic AMP in COS1 cells. Journal of Biological Chemistry, 284(26), pp. 17391-17403. (doi: 10.1074/jbc.M109.015370) (PMID:19423709) (PMCID:PMC2719379)

Borland, G., Smith, B.O. and Yarwood, S.J. (2009) EPAC proteins transduce diverse cellular actions of cAMP. British Journal of Pharmacology, 158(1), pp. 70-86. (doi: 10.1111/j.1476-5381.2008.00087.x)

Yarwood, S.J., Borland, G., Sands, W.A. and Palmer, T.M. (2008) Identification of CCAAT/Enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene. Journal of Biological Chemistry, 283(11), pp. 6843-6853. (doi: 10.1074/jbc.M710342200)

Borland, G., Edkins, A.L., Acharya, M., Matheson, J., White, L.J., Allen, J.M., Bonnefoy, J.-Y., Ozanne, B. W. and Cushley, W. (2007) vbeta5 Integrin Sustains Growth of Human Pre-B Cells through an RGD-independent Interaction with a Basic Domain of the CD23 Protein. Journal of Biological Chemistry, 282(37), pp. 27315-27326. (doi: 10.1074/jbc.M609335200)

Book Sections

Neil, J. C. , Gilroy, K., Borland, G., Hay, J. , Terry, A. and Kilbey, A. (2017) The RUNX genes as conditional oncogenes: insights from retroviral targeting and mouse models. In: Groner, Y., Ito, Y., Liu, P., Neil, J. C., Speck, N. A. and van Wijnen, A. (eds.) RUNX Proteins in Development and Cancer. Series: Advances in experimental medicine and biology (962). Springer, pp. 247-264. ISBN 9789811032318 (doi: 10.1007/978-981-10-3233-2_16)