Ms Duangkamon Loesbanluechai

  • Research Assistant (Host-Parasite Interactions & Pathogenesis)

Biography

February 2021-Present:  Postdoctoral Researcher, School of Biodiversity, One health & Veterinary medicine, University of Glasgow

2016 – 2020: Ph.D. in Molecular Medicine, Mahidol University                                  

2013 – 2015: M.Sc. in Clinical Haematology Sciences, Chulalongkorn University

2009 – 2012: B.Sc. in Medical Technology, Chulalongkorn University

Research interests

I have strong interests in parasite biology and the application of genome editing tools to dissect the biology of malaria parasites. Such approaches are important to understand the genetic factors controlling key aspects of the parasite life cycle such as transmission by the mosquitoes and provide tools to identify and validate candidate targets that would form the basis of urgent interventions needed to eliminate malaria. 

I completed my PhD at Mahidol University with additional funding from Newton Fund-TRF to undertake a research project at the Wellcome Sanger Institute. During this time, I used CRISPR/ Cas9 genome editing tools to generate mutant P. falciparum parasites which enabled us to identify parasite single nucleotide polymorphisms associated with drug resistance in Southeast Asia and the likely mechanisms driving these phenotypes.

I joined the Howick group in School of Biodiversity, One Health and Veterinary medicine at University of Glasgow in February 2021 as a postdoctoral researcher. Here, I’m currently working on the transmission stages of Plasmodium falciparum parasites with a goal of identifying the genetic determinants of vector-parasite tropism and how this varies between different mosquito species driving disease transmission.

Research groups

Publications

List by: Type | Date

Jump to: 2024 | 2021 | 2019 | 2018 | 2016
Number of items: 7.

2024

Xie, S. et al. (2024) Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature Communications, 15, 937. (doi: 10.1038/s41467-024-45224-z) (PMID:38297033) (PMCID:PMC10831071)

2021

Kümpornsin, K. et al. (2021) Lumefantrine attenuates Plasmodium falciparum artemisinin resistance during the early ring stage. International Journal for Parasitology: Drugs and Drug Resistance, 17, pp. 186-190. (doi: 10.1016/j.ijpddr.2021.09.005) (PMID:34673330) (PMCID:PMC8528645)

Atsawawaranunt, K. et al. (2021) COVID-19 transmission among healthcare workers at a quarantine facility in Thailand: genomic and outbreak investigations. American Journal of Tropical Medicine and Hygiene, 105(2), pp. 421-424. (doi: 10.4269/ajtmh.21-0344) (PMID:34170846) (PMCID:PMC8437180)

Mungaomklang, A. et al. (2021) Pitfalls of exceptions for COVID-19 travel quarantine: lessons from a dignitary visit to Thailand. Journal of Travel Medicine, 28(2), taab010. (doi: 10.1093/jtm/taab010) (PMID:33506268) (PMCID:PMC7901055)

2019

Loesbanluechai, D. et al. (2019) Overexpression of plasmepsin II and plasmepsin III does not directly cause reduction in Plasmodium falciparum sensitivity to artesunate, chloroquine and piperaquine. International Journal for Parasitology: Drugs and Drug Resistance, 9, pp. 16-22. (doi: 10.1016/j.ijpddr.2018.11.004) (PMID:30580023) (PMCID:PMC6304341)

2018

Bunditvorapoom, D. et al. (2018) Fitness loss under amino acid starvation in artemisinin-resistant Plasmodium falciparum isolates from Cambodia. Scientific Reports, 8(1), 12622. (doi: 10.1038/s41598-018-30593-5) (PMID:30135481) (PMCID:PMC6105667)

2016

Kochakarn, T., Kotanan, N., Kümpornsin, K., Loesbanluechai, D. , Thammasatta, M., Auewarakul, P., Wilairat, P. and Chookajorn, T. (2016) Comparative genome analysis between Southeast Asian and South American Zika viruses. Asian Pacific Journal of Tropical Medicine, 9(11), pp. 1048-1054. (doi: 10.1016/j.apjtm.2016.10.002) (PMID:27890363)

This list was generated on Fri May 24 06:39:09 2024 BST.
Jump to: Articles
Number of items: 7.

Articles

Xie, S. et al. (2024) Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature Communications, 15, 937. (doi: 10.1038/s41467-024-45224-z) (PMID:38297033) (PMCID:PMC10831071)

Kümpornsin, K. et al. (2021) Lumefantrine attenuates Plasmodium falciparum artemisinin resistance during the early ring stage. International Journal for Parasitology: Drugs and Drug Resistance, 17, pp. 186-190. (doi: 10.1016/j.ijpddr.2021.09.005) (PMID:34673330) (PMCID:PMC8528645)

Atsawawaranunt, K. et al. (2021) COVID-19 transmission among healthcare workers at a quarantine facility in Thailand: genomic and outbreak investigations. American Journal of Tropical Medicine and Hygiene, 105(2), pp. 421-424. (doi: 10.4269/ajtmh.21-0344) (PMID:34170846) (PMCID:PMC8437180)

Mungaomklang, A. et al. (2021) Pitfalls of exceptions for COVID-19 travel quarantine: lessons from a dignitary visit to Thailand. Journal of Travel Medicine, 28(2), taab010. (doi: 10.1093/jtm/taab010) (PMID:33506268) (PMCID:PMC7901055)

Loesbanluechai, D. et al. (2019) Overexpression of plasmepsin II and plasmepsin III does not directly cause reduction in Plasmodium falciparum sensitivity to artesunate, chloroquine and piperaquine. International Journal for Parasitology: Drugs and Drug Resistance, 9, pp. 16-22. (doi: 10.1016/j.ijpddr.2018.11.004) (PMID:30580023) (PMCID:PMC6304341)

Bunditvorapoom, D. et al. (2018) Fitness loss under amino acid starvation in artemisinin-resistant Plasmodium falciparum isolates from Cambodia. Scientific Reports, 8(1), 12622. (doi: 10.1038/s41598-018-30593-5) (PMID:30135481) (PMCID:PMC6105667)

Kochakarn, T., Kotanan, N., Kümpornsin, K., Loesbanluechai, D. , Thammasatta, M., Auewarakul, P., Wilairat, P. and Chookajorn, T. (2016) Comparative genome analysis between Southeast Asian and South American Zika viruses. Asian Pacific Journal of Tropical Medicine, 9(11), pp. 1048-1054. (doi: 10.1016/j.apjtm.2016.10.002) (PMID:27890363)

This list was generated on Fri May 24 06:39:09 2024 BST.