2024

Santi, A. et al. (2024) Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function. Science Signaling, (Accepted for Publication)

Fetit, R. et al. (2024) Characterising neutrophil subtypes in cancer using scRNA sequencing demonstrates the importance of IL-1β/CXCR2 axis in generation of metastasis specific neutrophils. Cancer Research Communications, 4(2), pp. 588-606. (doi: 10.1158/2767-9764.CRC-23-0319) (PMID:38358352) (PMCID:PMC10903300)

Derby, S. et al. (2024) Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalisation via macropinocytosis. Neuro-Oncology, (doi: 10.1093/neuonc/noad210) (PMID:37936324) (Early Online Publication)

2023

Farahmand, P. et al. (2023) Asbestos accelerates disease onset in a genetic model of malignant pleural mesothelioma. Frontiers in Toxicology, 5, 1200650. (doi: 10.3389/ftox.2023.1200650) (PMID:37441092) (PMCID:PMC10333928)

Schmidt, T. et al. (2023) eIF4A1-dependent mRNAs employ purine-rich 5’UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation. Nucleic Acids Research, 51(4), pp. 1859-1879. (doi: 10.1093/nar/gkad030) (PMID:36727461) (PMCID:PMC9976904)

2022

Leslie, J. et al. (2022) CXCR2 inhibition enables NASH-HCC immunotherapy. Gut, 71(10), pp. 2093-2106. (doi: 10.1136/gutjnl-2021-326259) (PMID:35477863) (PMCID:PMC9484388)

Müller, M. et al. (2022) Human-correlated genetic HCC models identify combination therapy for precision medicine [Pre-print]. Research Square, (doi: 10.21203/rs.3.rs-1638504/v1)

Humpton, T. J. et al. (2022) A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo. Science Signaling, 15(720), eabd9099. (doi: 10.1126/scisignal.abd9099) (PMID:35133863) (PMCID:PMC7612476)

2021

McCowan, J. et al. (2021) The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair. Science Immunology, 6(65), eabj2132. (doi: 10.1126/sciimmunol.abj2132) (PMID:34797692) (PMCID:PMC7612216)

Birch, J. et al. (2021) Inhibition of ATR prevents macropinocytosis driven retraction of neurites and opposes invasion in GBM. Research Square, (doi: 10.21203/rs.3.rs-967109/v1) (PMID:37936324)

Ntala, C. et al. (2021) Analysis of prostate cancer tumor microenvironment identifies reduced stromal CD4 effector T-cell infiltration in tumors with pelvic nodal metastasis. European Urology Open Science, 29, pp. 19-29. (doi: 10.1016/j.euros.2021.05.001) (PMID:34337530) (PMCID:PMC8317840)

McFarlane, A. J., Fercoq, F., Coffelt, S. B. and Carlin, L. M. (2021) Neutrophil dynamics in the tumor microenvironment. Journal of Clinical Investigation, 131(6), e143759. (doi: 10.1172/JCI143759) (PMID:33720040)

Brownlie, D., Doughty-Shenton, D., Soong, D. Y.H., Nixon, C., Carragher, N. O., Carlin, L. M. and Kitamura, T. (2021) Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β. Journal for ImmunoTherapy of Cancer, 9(1), e001740. (doi: 10.1136/jitc-2020-001740) (PMID:33472858) (PMCID:PMC7818844)

2020

Fercoq, F., Remion, E., Vallarino-Lhermitte, N., Alonso, J., Raveendran, L., Nixon, C., Le Quesne, J., Carlin, L. M. and Martin, C. (2020) Microfilaria-dependent thoracic pathology associated with eosinophilic and fibrotic polyps in filaria-infected rodents. Parasites and Vectors, 13, 531. (doi: 10.1186/s13071-020-04428-0) (PMID:33160409) (PMCID:PMC7648300)

Plant, T. et al. (2020) Semaphorin 3F signaling actively retains neutrophils at sites of inflammation. Journal of Clinical Investigation, 130(6), pp. 3221-3237. (doi: 10.1172/JCI130834) (PMID:32191647) (PMCID:PMC7259996)

Pillay, J. et al. (2020) Effect of the CXCR4 antagonist plerixafor on endogenous neutrophil dynamics in the bone marrow, lung and spleen. Journal of Leukocyte Biology, 107(6), pp. 1175-1185. (doi: 10.1002/JLB.1MA0420-571RR) (PMID:32374077)

Leung, E. Y.L. et al. (2020) NK cells augment oncolytic adenovirus cytotoxicity in ovarian cancer. Molecular Therapy - Oncolytics, 16, pp. 289-301. (doi: 10.1016/j.omto.2020.02.001) (PMID:32195317) (PMCID:PMC7068056)

2019

Patel, D. F. et al. (2019) Neutrophils restrain allergic airway inflammation by limiting ILC2 function and monocyte-dendritic cell antigen presentation. Science Immunology, 4(41), eaax7006. (doi: 10.1126/sciimmunol.aax7006) (PMID:31704734)

McCormick, B. et al. (2019) A negative feedback loop regulates integrin inactivation and promotes neutrophil recruitment to inflammatory sites. Journal of Immunology, 203(6), pp. 1579-1588. (doi: 10.4049/jimmunol.1900443) (PMID:31427445) (PMCID:PMC6731454)

Mackey, J. B.G., Coffelt, S. B. and Carlin, L. M. (2019) Neutrophil maturity in cancer. Frontiers in Immunology, 10, 1912. (doi: 10.3389/fimmu.2019.01912) (PMID:31474989) (PMCID:PMC6702268)

Puttur, F. et al. (2019) Pulmonary environmental cues drive group 2 innate lymphoid cell dynamics in mice and humans. Science Immunology, 4(36), eaav7638. (doi: 10.1126/sciimmunol.aav7638) (PMID:31175176) (PMCID:PMC6744282)

2018

Novo, D. et al. (2018) Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels. Nature Communications, 9, 5069. (doi: 10.1038/s41467-018-07339-y) (PMID:30498210) (PMCID:PMC6265295)

Riley, J. S. et al. (2018) Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis. EMBO Journal, 37(17), e99238. (doi: 10.15252/embj.201899238) (PMID:30049712) (PMCID:PMC6120664)

Brown, E., Carlin, L. M. , Nerlov, C., Lo Celso, C. and Poole, A. W. (2018) Multiple membrane extrusion sites drive megakaryocyte migration into bone marrow blood vessels. Life Science Alliance, 1(2), e201800061. (doi: 10.26508/lsa.201800061) (PMID:30393781) (PMCID:PMC6211653)

Tung, S. L. et al. (2018) Regulatory T cell-derived extracellular vesicles modify dendritic cell function. Scientific Reports, 8, 6065. (doi: 10.1038/s41598-018-24531-8) (PMID:29666503) (PMCID:PMC5904112)

Duarte, D. et al. (2018) Inhibition of endosteal vascular niche remodeling rescues hematopoietic stem cell loss in AML. Cell Stem Cell, 22(1), 64-77.e6. (doi: 10.1016/j.stem.2017.11.006) (PMID:29276143) (PMCID:PMC5766835)

2017

Reid, S. E. et al. (2017) Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium. EMBO Journal, 36(16), pp. 2373-2389. (doi: 10.15252/embj.201694912) (PMID:28694244) (PMCID:PMC5556271)

Secklehner, J., Lo Celso, C. and Carlin, L. M. (2017) Intravital microscopy in historic and contemporary immunology. Immunology and Cell Biology, 95(6), pp. 506-513. (doi: 10.1038/icb.2017.25) (PMID:28366932) (PMCID:PMC6095455)

Karadjian, G., Fercoq, F., Pionnier, N., Vallarino-Lhermitte, N., Lefoulon, E., Nieguitsila, A., Specht, S., Carlin, L. M. and Martin, C. (2017) Migratory phase of Litomosoides sigmodontis filarial infective larvae is associated with pathology and transient increase of S100A9 expressing neutrophils in the lung. PLoS Neglected Tropical Diseases, 11(5), e0005596. (doi: 10.1371/journal.pntd.0005596) (PMID:28486498) (PMCID:PMC5438187)

Irshad, S. et al. (2017) RORγt+ innate lymphoid cells promote lymph node metastasis of breast cancers. Cancer Research, 77(5), pp. 1083-1096. (doi: 10.1158/0008-5472.CAN-16-0598) (PMID:28082403)

2015

Collison, J. L., Carlin, L. M. , Eichmann, M., Geissmann, F. and Peakman, M. (2015) Heterogeneity in the locomotory behavior of human monocyte subsets over human vascular endothelium in vitro. Journal of Immunology, 195(3), pp. 1162-1170. (doi: 10.4049/jimmunol.1401806) (PMID:26085686)

Kostelec, P. D., Carlin, L. M. and Glocker, B. (2015) Learning to Detect and Track Cells for Quantitative Analysis of Time-Lapse Microscopic Image Sequences. In: 2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI), New York, NY, USA, 16-19 Apr 2015, pp. 1544-1547. ISBN 9781479923748 (doi: 10.1109/ISBI.2015.7164172)

2013

Carlin, L.M. , Auffray, C. and Geissmann, F. (2013) Measuring intravascular migration of mouse Ly6Clow monocytes in vivo using intravital microscopy. Current Protocols in Immunology, 101(1), 14.33.1-14.33.16. (doi: 10.1002/0471142735.im1433s101) (PMID:23564685)

Carlin, L. M. , Stamatiades, E. G., Auffray, C., Hanna, R. N., Glover, L., Vizcay-Barrena, G., Hedrick, C. C., Cook, H. T., Diebold, S. and Geissmann, F. (2013) Nr4a1-dependent Ly6Clow monocytes monitor endothelial cells and orchestrate their disposal. Cell, 153(2), pp. 362-375. (doi: 10.1016/j.cell.2013.03.010) (PMID:23582326) (PMCID:PMC3898614)

Bachy, V. et al. (2013) Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays. Proceedings of the National Academy of Sciences of the United States of America, 110(8), pp. 3041-3046. (doi: 10.1073/pnas.1214449110) (PMID:23386724) (PMCID:PMC3581957)

2012

Matthews, D. R. et al. (2012) A multi-functional imaging approach to high-content protein interaction screening. PLoS ONE, 7(4), e33231. (doi: 10.1371/journal.pone.0033231) (PMID:22506000) (PMCID:PMC3323588)

2011

Carlin, L. M. et al. (2011) A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse. Science Signaling, 4(201), ra81. (doi: 10.1126/scisignal.2001729) (PMID:22126964)

Hanna, R. N., Carlin, L. M. , Hubbeling, H. G., Nackiewicz, D., Green, A. M., Punt, J. A., Geissmann, F. and Hedrick, C. C. (2011) The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C− monocytes. Nature Immunology, 12(8), pp. 778-785. (doi: 10.1038/ni.2063) (PMID:21725321) (PMCID:PMC3324395)

2010

Heasman, S. J., Carlin, L. M. , Cox, S., Ng, T. and Ridley, A. J. (2010) Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration. Journal of Cell Biology, 190(4), pp. 553-563. (doi: 10.1083/jcb.201002067) (PMID:20733052) (PMCID:PMC2928012)

Matthew, D.R., Carlin, L.M. , Ofo, E., Barber, P.R., Vojnovic, B., Irving, M., Ng, T. and Ameer-Beg, S.M. (2010) Time-lapse FRET microscopy using fluorescence anisotropy. Journal of Microscopy, 237(1), pp. 51-62. (doi: 10.1111/j.1365-2818.2009.03301.x) (PMID:20055918)

Carlin, L. M. , Makrogianneli, K., Keppler, M., Fruhwirth, G. O. and Ng, T. (2010) Visualisation of signalling in immune cells. In: Marelli-Berg, F. M. and Nourshargh, S. (eds.) T-Cell Trafficking: Methods and Protocols. Series: Methods in molecular biology (616). Humana Press: New York, NY, pp. 97-113. ISBN 9781607614609 (doi: 10.1007/978-1-60761-461-6_7)

2009

Makrogianneli, K., Carlin, L. M. , Keppler, M. D., Matthews, D. R., Ofo, E., Coolen, A., Ameer-Beg, S. M., Barber, P. R., Vojnovic, B. and Ng, T. (2009) Integrating receptor signal inputs that influence small Rho GTPase activation dynamics at the immunological synapse. Molecular and Cellular Biology, 29(11), pp. 2997-3006. (doi: 10.1128/MCB.01008-08) (PMID:19307303) (PMCID:PMC2682016)

Agromayor, M., Carlton, J. G., Phelan, J. P., Matthews, D. R., Carlin, L. M. , Ameer-Beg, S., Bowers, K. and Martin-Serrano, J. (2009) Essential role of hIST1 in cytokinesis. Molecular Biology of the Cell, 20(5), pp. 1374-1387. (doi: 10.1091/mbc.E08-05-0474) (PMID:19129480) (PMCID:PMC2649264)

Barber, P.R., Ameer-Beg, S.M., Gilbey, J., Carlin, L.M. , Keppler, M., Ng, T.C. and Vojnovic, B. (2009) Multiphoton time-domain fluorescence lifetime imaging microscopy: practical application to protein–protein interactions using global analysis. Journal of the Royal Society: Interface, 6(Suppl1), S93-S105. (doi: 10.1098/rsif.2008.0451.focus) (PMCID:PMC2706460)

2008

Barber, P.R. et al. (2008) Towards High-Throughput FLIM for Protein-Protein Interaction Screening of Live Cells and Tissue Microarrays. In: 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Paris, France, 14-17 May 2008, pp. 356-359. ISBN 9781424420025 (doi: 10.1109/ISBI.2008.4541006)

Matthews, D. R. et al. (2008) A High-Content Screening Platform Utilizing Polarization Anisotropy and FLIM Microscopy. In: SPIE BiOS 2008, San Jose, CA, USA, 21-23 Jan 2008, pp. 685919-1. ISBN 9780819470348 (doi: 10.1117/12.763310)

2005

Carlin, L. M. , Yanagi, K., Verhoef, A., Noelte-'t Hoen, E. N.M., Yates, J., Gardner, L., Lamb, J., Lombardi, G., Dallman, M. J. and Davis, D. M. (2005) Secretion of IFN- and not IL-2 by anergic human T cells correlates with assembly of an immature immune synapse. Blood, 106(12), pp. 3874-3879. (doi: 10.1182/blood-2005-03-0996) (PMID:16099874)

2004

Vanherberghen, B., Andersson, K., Carlin, L. M. , Nolte-`t Hoen, E. N.M., Williams, G. S., Hoglund, P. and Davis, D. M. (2004) Human and murine inhibitory natural killer cell receptors transfer from natural killer cells to target cells. Proceedings of the National Academy of Sciences of the United States of America, 101(48), pp. 16873-16878. (doi: 10.1073/pnas.0406240101) (PMID:15550544) (PMCID:PMC534731)

Standeven, L. J., Carlin, L. M. , Borszcz, P., Davis, D. M. and Burshtyn, D. N. (2004) The actin cytoskeleton controls the efficiency of killer Ig-like receptor accumulation at inhibitory NK cell immune synapses. Journal of Immunology, 173(9), pp. 5617-5625. (doi: 10.4049/jimmunol.173.9.5617) (PMID:15494512)

2003

Davis, D. M., Igakura, T., McCann, F. E., Carlin, L. M. , Andersson, K., Vanherberghen, B., Sjöström, A., Bangham, C. R.M. and Höglund, P. (2003) The protean immune cell synapse: a supramolecular structure with many functions. Seminars in Immunology, 15(6), pp. 317-324. (doi: 10.1016/j.smim.2003.09.005) (PMID:15001170)

McCann, F. E., Vanherberghen, B., Eleme, K., Carlin, L. M. , Newsam, R. J., Goulding, D. and Davis, D. M. (2003) The size of the synaptic cleft and distinct distributions of filamentous actin, ezrin, CD43, and CD45 at activating and inhibitory human NK cell immune synapses. Journal of Immunology, 170(6), pp. 2862-2870. (doi: 10.4049/jimmunol.170.6.2862) (PMID:12626536)

2002

McCann, F. E., Suhling, K., Carlin, L. M. , Eleme, K., Taner, S. B., Yanagi, K., Vanherberghen, B., French, P. M.W. and Davis, D. M. (2002) Imaging immune surveillance by T cells and NK cells. Immunological Reviews, 189(1), pp. 179-192. (doi: 10.1034/j.1600-065X.2002.18915.x) (PMID:12445274)

2001

Carlin, L. , Eleme, K., McCann, F. E. and Davis, D. M. (2001) Intercellular transfer and supramolecular organization of human leukocyte antigen C at inhibitory natural killer cell immune synapses. Journal of Experimental Medicine, 194(10), pp. 1507-1517. (doi: 10.1084/jem.194.10.1507) (PMID:11714757) (PMCID:PMC2193674)

Articles

Santi, A. et al. (2024) Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function. Science Signaling, (Accepted for Publication)

Fetit, R. et al. (2024) Characterising neutrophil subtypes in cancer using scRNA sequencing demonstrates the importance of IL-1β/CXCR2 axis in generation of metastasis specific neutrophils. Cancer Research Communications, 4(2), pp. 588-606. (doi: 10.1158/2767-9764.CRC-23-0319) (PMID:38358352) (PMCID:PMC10903300)

Derby, S. et al. (2024) Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalisation via macropinocytosis. Neuro-Oncology, (doi: 10.1093/neuonc/noad210) (PMID:37936324) (Early Online Publication)

Farahmand, P. et al. (2023) Asbestos accelerates disease onset in a genetic model of malignant pleural mesothelioma. Frontiers in Toxicology, 5, 1200650. (doi: 10.3389/ftox.2023.1200650) (PMID:37441092) (PMCID:PMC10333928)

Schmidt, T. et al. (2023) eIF4A1-dependent mRNAs employ purine-rich 5’UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation. Nucleic Acids Research, 51(4), pp. 1859-1879. (doi: 10.1093/nar/gkad030) (PMID:36727461) (PMCID:PMC9976904)

Leslie, J. et al. (2022) CXCR2 inhibition enables NASH-HCC immunotherapy. Gut, 71(10), pp. 2093-2106. (doi: 10.1136/gutjnl-2021-326259) (PMID:35477863) (PMCID:PMC9484388)

Müller, M. et al. (2022) Human-correlated genetic HCC models identify combination therapy for precision medicine [Pre-print]. Research Square, (doi: 10.21203/rs.3.rs-1638504/v1)

Humpton, T. J. et al. (2022) A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo. Science Signaling, 15(720), eabd9099. (doi: 10.1126/scisignal.abd9099) (PMID:35133863) (PMCID:PMC7612476)

McCowan, J. et al. (2021) The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair. Science Immunology, 6(65), eabj2132. (doi: 10.1126/sciimmunol.abj2132) (PMID:34797692) (PMCID:PMC7612216)

Birch, J. et al. (2021) Inhibition of ATR prevents macropinocytosis driven retraction of neurites and opposes invasion in GBM. Research Square, (doi: 10.21203/rs.3.rs-967109/v1) (PMID:37936324)

Ntala, C. et al. (2021) Analysis of prostate cancer tumor microenvironment identifies reduced stromal CD4 effector T-cell infiltration in tumors with pelvic nodal metastasis. European Urology Open Science, 29, pp. 19-29. (doi: 10.1016/j.euros.2021.05.001) (PMID:34337530) (PMCID:PMC8317840)

McFarlane, A. J., Fercoq, F., Coffelt, S. B. and Carlin, L. M. (2021) Neutrophil dynamics in the tumor microenvironment. Journal of Clinical Investigation, 131(6), e143759. (doi: 10.1172/JCI143759) (PMID:33720040)

Brownlie, D., Doughty-Shenton, D., Soong, D. Y.H., Nixon, C., Carragher, N. O., Carlin, L. M. and Kitamura, T. (2021) Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β. Journal for ImmunoTherapy of Cancer, 9(1), e001740. (doi: 10.1136/jitc-2020-001740) (PMID:33472858) (PMCID:PMC7818844)

Fercoq, F., Remion, E., Vallarino-Lhermitte, N., Alonso, J., Raveendran, L., Nixon, C., Le Quesne, J., Carlin, L. M. and Martin, C. (2020) Microfilaria-dependent thoracic pathology associated with eosinophilic and fibrotic polyps in filaria-infected rodents. Parasites and Vectors, 13, 531. (doi: 10.1186/s13071-020-04428-0) (PMID:33160409) (PMCID:PMC7648300)

Plant, T. et al. (2020) Semaphorin 3F signaling actively retains neutrophils at sites of inflammation. Journal of Clinical Investigation, 130(6), pp. 3221-3237. (doi: 10.1172/JCI130834) (PMID:32191647) (PMCID:PMC7259996)

Pillay, J. et al. (2020) Effect of the CXCR4 antagonist plerixafor on endogenous neutrophil dynamics in the bone marrow, lung and spleen. Journal of Leukocyte Biology, 107(6), pp. 1175-1185. (doi: 10.1002/JLB.1MA0420-571RR) (PMID:32374077)

Leung, E. Y.L. et al. (2020) NK cells augment oncolytic adenovirus cytotoxicity in ovarian cancer. Molecular Therapy - Oncolytics, 16, pp. 289-301. (doi: 10.1016/j.omto.2020.02.001) (PMID:32195317) (PMCID:PMC7068056)

Patel, D. F. et al. (2019) Neutrophils restrain allergic airway inflammation by limiting ILC2 function and monocyte-dendritic cell antigen presentation. Science Immunology, 4(41), eaax7006. (doi: 10.1126/sciimmunol.aax7006) (PMID:31704734)

McCormick, B. et al. (2019) A negative feedback loop regulates integrin inactivation and promotes neutrophil recruitment to inflammatory sites. Journal of Immunology, 203(6), pp. 1579-1588. (doi: 10.4049/jimmunol.1900443) (PMID:31427445) (PMCID:PMC6731454)

Mackey, J. B.G., Coffelt, S. B. and Carlin, L. M. (2019) Neutrophil maturity in cancer. Frontiers in Immunology, 10, 1912. (doi: 10.3389/fimmu.2019.01912) (PMID:31474989) (PMCID:PMC6702268)

Puttur, F. et al. (2019) Pulmonary environmental cues drive group 2 innate lymphoid cell dynamics in mice and humans. Science Immunology, 4(36), eaav7638. (doi: 10.1126/sciimmunol.aav7638) (PMID:31175176) (PMCID:PMC6744282)

Novo, D. et al. (2018) Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels. Nature Communications, 9, 5069. (doi: 10.1038/s41467-018-07339-y) (PMID:30498210) (PMCID:PMC6265295)

Riley, J. S. et al. (2018) Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis. EMBO Journal, 37(17), e99238. (doi: 10.15252/embj.201899238) (PMID:30049712) (PMCID:PMC6120664)

Brown, E., Carlin, L. M. , Nerlov, C., Lo Celso, C. and Poole, A. W. (2018) Multiple membrane extrusion sites drive megakaryocyte migration into bone marrow blood vessels. Life Science Alliance, 1(2), e201800061. (doi: 10.26508/lsa.201800061) (PMID:30393781) (PMCID:PMC6211653)

Tung, S. L. et al. (2018) Regulatory T cell-derived extracellular vesicles modify dendritic cell function. Scientific Reports, 8, 6065. (doi: 10.1038/s41598-018-24531-8) (PMID:29666503) (PMCID:PMC5904112)

Duarte, D. et al. (2018) Inhibition of endosteal vascular niche remodeling rescues hematopoietic stem cell loss in AML. Cell Stem Cell, 22(1), 64-77.e6. (doi: 10.1016/j.stem.2017.11.006) (PMID:29276143) (PMCID:PMC5766835)

Reid, S. E. et al. (2017) Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium. EMBO Journal, 36(16), pp. 2373-2389. (doi: 10.15252/embj.201694912) (PMID:28694244) (PMCID:PMC5556271)

Secklehner, J., Lo Celso, C. and Carlin, L. M. (2017) Intravital microscopy in historic and contemporary immunology. Immunology and Cell Biology, 95(6), pp. 506-513. (doi: 10.1038/icb.2017.25) (PMID:28366932) (PMCID:PMC6095455)

Karadjian, G., Fercoq, F., Pionnier, N., Vallarino-Lhermitte, N., Lefoulon, E., Nieguitsila, A., Specht, S., Carlin, L. M. and Martin, C. (2017) Migratory phase of Litomosoides sigmodontis filarial infective larvae is associated with pathology and transient increase of S100A9 expressing neutrophils in the lung. PLoS Neglected Tropical Diseases, 11(5), e0005596. (doi: 10.1371/journal.pntd.0005596) (PMID:28486498) (PMCID:PMC5438187)

Irshad, S. et al. (2017) RORγt+ innate lymphoid cells promote lymph node metastasis of breast cancers. Cancer Research, 77(5), pp. 1083-1096. (doi: 10.1158/0008-5472.CAN-16-0598) (PMID:28082403)

Collison, J. L., Carlin, L. M. , Eichmann, M., Geissmann, F. and Peakman, M. (2015) Heterogeneity in the locomotory behavior of human monocyte subsets over human vascular endothelium in vitro. Journal of Immunology, 195(3), pp. 1162-1170. (doi: 10.4049/jimmunol.1401806) (PMID:26085686)

Carlin, L.M. , Auffray, C. and Geissmann, F. (2013) Measuring intravascular migration of mouse Ly6Clow monocytes in vivo using intravital microscopy. Current Protocols in Immunology, 101(1), 14.33.1-14.33.16. (doi: 10.1002/0471142735.im1433s101) (PMID:23564685)

Carlin, L. M. , Stamatiades, E. G., Auffray, C., Hanna, R. N., Glover, L., Vizcay-Barrena, G., Hedrick, C. C., Cook, H. T., Diebold, S. and Geissmann, F. (2013) Nr4a1-dependent Ly6Clow monocytes monitor endothelial cells and orchestrate their disposal. Cell, 153(2), pp. 362-375. (doi: 10.1016/j.cell.2013.03.010) (PMID:23582326) (PMCID:PMC3898614)

Bachy, V. et al. (2013) Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays. Proceedings of the National Academy of Sciences of the United States of America, 110(8), pp. 3041-3046. (doi: 10.1073/pnas.1214449110) (PMID:23386724) (PMCID:PMC3581957)

Matthews, D. R. et al. (2012) A multi-functional imaging approach to high-content protein interaction screening. PLoS ONE, 7(4), e33231. (doi: 10.1371/journal.pone.0033231) (PMID:22506000) (PMCID:PMC3323588)

Carlin, L. M. et al. (2011) A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse. Science Signaling, 4(201), ra81. (doi: 10.1126/scisignal.2001729) (PMID:22126964)

Hanna, R. N., Carlin, L. M. , Hubbeling, H. G., Nackiewicz, D., Green, A. M., Punt, J. A., Geissmann, F. and Hedrick, C. C. (2011) The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C− monocytes. Nature Immunology, 12(8), pp. 778-785. (doi: 10.1038/ni.2063) (PMID:21725321) (PMCID:PMC3324395)

Heasman, S. J., Carlin, L. M. , Cox, S., Ng, T. and Ridley, A. J. (2010) Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration. Journal of Cell Biology, 190(4), pp. 553-563. (doi: 10.1083/jcb.201002067) (PMID:20733052) (PMCID:PMC2928012)

Matthew, D.R., Carlin, L.M. , Ofo, E., Barber, P.R., Vojnovic, B., Irving, M., Ng, T. and Ameer-Beg, S.M. (2010) Time-lapse FRET microscopy using fluorescence anisotropy. Journal of Microscopy, 237(1), pp. 51-62. (doi: 10.1111/j.1365-2818.2009.03301.x) (PMID:20055918)

Makrogianneli, K., Carlin, L. M. , Keppler, M. D., Matthews, D. R., Ofo, E., Coolen, A., Ameer-Beg, S. M., Barber, P. R., Vojnovic, B. and Ng, T. (2009) Integrating receptor signal inputs that influence small Rho GTPase activation dynamics at the immunological synapse. Molecular and Cellular Biology, 29(11), pp. 2997-3006. (doi: 10.1128/MCB.01008-08) (PMID:19307303) (PMCID:PMC2682016)

Agromayor, M., Carlton, J. G., Phelan, J. P., Matthews, D. R., Carlin, L. M. , Ameer-Beg, S., Bowers, K. and Martin-Serrano, J. (2009) Essential role of hIST1 in cytokinesis. Molecular Biology of the Cell, 20(5), pp. 1374-1387. (doi: 10.1091/mbc.E08-05-0474) (PMID:19129480) (PMCID:PMC2649264)

Barber, P.R., Ameer-Beg, S.M., Gilbey, J., Carlin, L.M. , Keppler, M., Ng, T.C. and Vojnovic, B. (2009) Multiphoton time-domain fluorescence lifetime imaging microscopy: practical application to protein–protein interactions using global analysis. Journal of the Royal Society: Interface, 6(Suppl1), S93-S105. (doi: 10.1098/rsif.2008.0451.focus) (PMCID:PMC2706460)

Carlin, L. M. , Yanagi, K., Verhoef, A., Noelte-'t Hoen, E. N.M., Yates, J., Gardner, L., Lamb, J., Lombardi, G., Dallman, M. J. and Davis, D. M. (2005) Secretion of IFN- and not IL-2 by anergic human T cells correlates with assembly of an immature immune synapse. Blood, 106(12), pp. 3874-3879. (doi: 10.1182/blood-2005-03-0996) (PMID:16099874)

Vanherberghen, B., Andersson, K., Carlin, L. M. , Nolte-`t Hoen, E. N.M., Williams, G. S., Hoglund, P. and Davis, D. M. (2004) Human and murine inhibitory natural killer cell receptors transfer from natural killer cells to target cells. Proceedings of the National Academy of Sciences of the United States of America, 101(48), pp. 16873-16878. (doi: 10.1073/pnas.0406240101) (PMID:15550544) (PMCID:PMC534731)

Standeven, L. J., Carlin, L. M. , Borszcz, P., Davis, D. M. and Burshtyn, D. N. (2004) The actin cytoskeleton controls the efficiency of killer Ig-like receptor accumulation at inhibitory NK cell immune synapses. Journal of Immunology, 173(9), pp. 5617-5625. (doi: 10.4049/jimmunol.173.9.5617) (PMID:15494512)

Davis, D. M., Igakura, T., McCann, F. E., Carlin, L. M. , Andersson, K., Vanherberghen, B., Sjöström, A., Bangham, C. R.M. and Höglund, P. (2003) The protean immune cell synapse: a supramolecular structure with many functions. Seminars in Immunology, 15(6), pp. 317-324. (doi: 10.1016/j.smim.2003.09.005) (PMID:15001170)

McCann, F. E., Vanherberghen, B., Eleme, K., Carlin, L. M. , Newsam, R. J., Goulding, D. and Davis, D. M. (2003) The size of the synaptic cleft and distinct distributions of filamentous actin, ezrin, CD43, and CD45 at activating and inhibitory human NK cell immune synapses. Journal of Immunology, 170(6), pp. 2862-2870. (doi: 10.4049/jimmunol.170.6.2862) (PMID:12626536)

McCann, F. E., Suhling, K., Carlin, L. M. , Eleme, K., Taner, S. B., Yanagi, K., Vanherberghen, B., French, P. M.W. and Davis, D. M. (2002) Imaging immune surveillance by T cells and NK cells. Immunological Reviews, 189(1), pp. 179-192. (doi: 10.1034/j.1600-065X.2002.18915.x) (PMID:12445274)

Carlin, L. , Eleme, K., McCann, F. E. and Davis, D. M. (2001) Intercellular transfer and supramolecular organization of human leukocyte antigen C at inhibitory natural killer cell immune synapses. Journal of Experimental Medicine, 194(10), pp. 1507-1517. (doi: 10.1084/jem.194.10.1507) (PMID:11714757) (PMCID:PMC2193674)

Book Sections

Carlin, L. M. , Makrogianneli, K., Keppler, M., Fruhwirth, G. O. and Ng, T. (2010) Visualisation of signalling in immune cells. In: Marelli-Berg, F. M. and Nourshargh, S. (eds.) T-Cell Trafficking: Methods and Protocols. Series: Methods in molecular biology (616). Humana Press: New York, NY, pp. 97-113. ISBN 9781607614609 (doi: 10.1007/978-1-60761-461-6_7)

Conference Proceedings

Kostelec, P. D., Carlin, L. M. and Glocker, B. (2015) Learning to Detect and Track Cells for Quantitative Analysis of Time-Lapse Microscopic Image Sequences. In: 2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI), New York, NY, USA, 16-19 Apr 2015, pp. 1544-1547. ISBN 9781479923748 (doi: 10.1109/ISBI.2015.7164172)

Barber, P.R. et al. (2008) Towards High-Throughput FLIM for Protein-Protein Interaction Screening of Live Cells and Tissue Microarrays. In: 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Paris, France, 14-17 May 2008, pp. 356-359. ISBN 9781424420025 (doi: 10.1109/ISBI.2008.4541006)

Matthews, D. R. et al. (2008) A High-Content Screening Platform Utilizing Polarization Anisotropy and FLIM Microscopy. In: SPIE BiOS 2008, San Jose, CA, USA, 21-23 Jan 2008, pp. 685919-1. ISBN 9780819470348 (doi: 10.1117/12.763310)