Dr Kristina Kirschner
- Research Associate (Epigenetics)
Kristina received her PhD from the University of Edinburgh characterising one of the first premature ageing mouse models. Her interest in ageing and cancer continued throughout her postdoc at the CRUK Cambridge Institute and at the Department of Haematology at the University of Cambridge, where she worked on the functional genomics of p53 in senescence and on haematopoiesis in ageing using single cell approaches. Kristina recently moved to the Institute of Cancer Sciences at the University of Glasgow, continuing her work in cancer heterogeneity and age- dependence of tumorigenesis as a junior group leader. Kristina also runs the single cell genomics core facility for the Institute for Cancer Sciences.
Wellcome Trust ISSF Fellowship 2016-2018
EHA-ASH TRTH Training Fellowship 2018
Kristina is interested in the interplay between ageing and cancer, using a variety of model systems.
Current projects are:
- Elucidating heterogeneity in the ageing haematopoietic stem cell compartment
- Exploring secondary senescence pathways in vitro and in vivo
- Defining mutational and epigenetic changes in patients with Myeloproliferative Disease
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Elucidating metabolomics changes in myeloproliferative neoplasms
2019 - 2020
- Defining Epigenetic age as a novel tool for cancer grading
NHS Greater Glasgow and Clyde
2019 - 2019
- ERADICATION OF THE LEUKAEMIC CLONE IN MYELOPROLIFERATIVE NEOPLASMS
University of Manchester
2018 - 2019
- Support for Epigenetics research
Medical Research Council
2017 - 2017
- Fellowship Award:Elucidating the response of the aged transcriptome and genome to oncogenic stress in haematopoietic stem cells using single cell approaches
2016 - 2018
I currently supervise one Ph.D. student as primary supervisor entitled "Heterogeneity within the ageing human haemopoietic compartment and predisposition to cancer". This project is funded by the MRC DTP programme in collaboration with Prof. Mhairi Copland (UoG) and Dr. Tamir Chandra at the University if Edinburgh.
Kristina currently teaches on the Master for Cancer Sciences programme and is involved with Master of Research student training.