Dr David Bryant

  • Senior Lecturer (Beatson Institute for Cancer Research)

Research interests

Link to research page in CRUK Beatson Institute


Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Dissecting the role of the metastasis-promoting protein Podocalyxin
    The Royal Society
    2017 - 2019
     

Publications

List by: Type | Date

Jump to: 2018 | 2017 | 2016 | 2015 | 2014 | 2012 | 2011 | 2010 | 2008 | 2007 | 2005 | 2004
Number of items: 28.

2018

Román-Fernández, Á. , Roignot, J., Sandilands, E., Nacke, M., Mansour, M. A., McGarry, L., Shanks, E., Mostov, K. E. and Bryant, D. M. (2018) The phospholipid PI(3,4)P2 is an apical identity determinant. Nature Communications, 9, 5041. (doi:10.1038/s41467-018-07464-8) (PMID:30487552) (PMCID:PMC6262019)

2017

Datta, A., Sandilands, E., Mostov, K. E. and Bryant, D. M. (2017) Fibroblast-derived HGF drives acinar lung cancer cell polarization through integrin-dependent RhoA-ROCK1 inhibition. Cellular Signalling, 40, pp. 91-98. (doi:10.1016/j.cellsig.2017.09.001) (PMID:28888686)

Gao, L., Yang, Z., Hiremath, C., Zimmerman, S. E., Long, B., Brakeman, P. R., Mostov, K. E., Bryant, D. M. , Luby-Phelps, K. and Marciano, D. K. (2017) Developing renal tubules orient cell division via Afadin to position the tubule lumen. Development, 144(19), pp. 3511-3520. (doi:10.1242/dev.148908) (PMID:28860115)

Reid, S. E. et al. (2017) Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium. EMBO Journal, 36(16), pp. 2373-2389. (doi:10.15252/embj.201694912) (PMID:28694244) (PMCID:PMC5556271)

Bryant, D. and Johnson, A. (2017) Meeting report - Intercellular interactions in context: towards a mechanistic understanding of cells in organs. Journal of Cell Science, 130(13), pp. 2083-2085. (doi:10.1242/jcs.205740) (PMID:28738319)

Ruch, T. R., Bryant, D. M. , Mostov, K. E., Engel, J. N. and Yap, A. (2017) Par3 integrates Tiam1 and phosphatidylinositol 3-kinase signaling to change apical membrane identity. Molecular Biology of the Cell, 28(2), pp. 252-260. (doi:10.1091/mbc.E16-07-0541) (PMID:27881661)

2016

Bryant, D. M. and Yap, A. S. (2016) Editorial overview: Membrane traffic and cell polarity. Traffic, 17(12), pp. 1231-1232. (doi:10.1111/tra.12433) (PMID:27885792)

Roman-Fernandez, A. and Bryant, D. M. (2016) Complex polarity: building multicellular tissues through apical membrane traffic. Traffic, 17(12), pp. 1244-1261. (doi:10.1111/tra.12417) (PMID:27281121)

Yang, Z., Zimmerman, S. E., Tsunezumi, J., Braitsch, C., Trent, C., Bryant, D. M. , Cleaver, O., González-Manchón, C. and Marciano, D. K. (2016) Role of CD34 family members in lumen formation in the developing kidney. Developmental Biology, 418(1), pp. 66-74. (doi:10.1016/j.ydbio.2016.08.009) (PMID:27542690)

2015

Overeem, A. W., Bryant, D. M. and van IJzendoorn, S. C.D. (2015) Mechanisms of apical–basal axis orientation and epithelial lumen positioning. Trends in Cell Biology, 25(8), pp. 476-485. (doi:10.1016/j.tcb.2015.04.002) (PMID:25941134)

2014

Bryant, D. M. et al. (2014) A molecular switch for the orientation of epithelial cell polarization. Developmental Cell, 31(2), pp. 171-187. (doi:10.1016/j.devcel.2014.08.027) (PMID:25307480) (PMCID:PMC4248238)

Tran, C. S. et al. (2014) Host cell polarity proteins participate in innate immunity to Pseudomonas aeruginosa infection. Cell Host and Microbe, 15(5), pp. 636-643. (doi:10.1016/j.chom.2014.04.007) (PMID:24832456) (PMCID:PMC4062193)

2012

Apodaca, G., Gallo, L. I. and Bryant, D. M. (2012) Role of membrane traffic in the generation of epithelial cell asymmetry. Nature Cell Biology, 14(12), pp. 1235-1243. (doi:10.1038/ncb2635)

Gálvez-Santisteban, M. et al. (2012) Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells. Nature Cell Biology, 14(8), pp. 838-849. (doi:10.1038/ncb2541) (PMID:22820376) (PMCID:PMC3433678)

2011

Su, T., Chapin, S. J., Bryant, D. M. , Shewan, A. M., Young, K. and Mostov, K. E. (2011) Reduced immunoglobulin A transcytosis associated with immunoglobulin A nephropathy and nasopharyngeal carcinoma. Journal of Biological Chemistry, 286(52), pp. 44921-44925. (doi:10.1074/jbc.M111.296731)

Lepanto, P., Bryant, D. M. , Rossello, J., Datta, A., Mostov, K. E. and Kierbel, A. (2011) Pseudomonas aeruginosa interacts with epithelial cells rapidly forming aggregates that are internalized by a Lyn-dependent mechanism. Cellular Microbiology, 13(8), pp. 1212-1222. (doi:10.1111/j.1462-5822.2011.01611.x)

Marciano, D. K., Brakeman, P. R., Lee, C.-Z., Spivak, N., Eastburn, D. J., Bryant, D. M. , Beaudoin, G. M., Hofmann, I., Mostov, K. E. and Reichardt, L. F. (2011) p120 catenin is required for normal renal tubulogenesis and glomerulogenesis. Development, 138(10), pp. 2099-2109. (doi:10.1242/dev.056564)

Roland, J. T., Bryant, D. M. , Datta, A., Itzen, A., Mostov, K. E. and Goldenring, J. R. (2011) Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization. Proceedings of the National Academy of Sciences of the United States of America, 108(7), pp. 2789-2794. (doi:10.1073/pnas.1010754108)

Datta, A., Bryant, D. M. and Mostov, K. E. (2011) Molecular regulation of lumen morphogenesis. Current Biology, 21(3), R126-R136. (doi:10.1016/j.cub.2010.12.003)

2010

Su, T. et al. (2010) A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor. Nature Cell Biology, 12(12), pp. 1143-1153. (doi:10.1038/ncb2118)

Bryant, D. M. , Datta, A., Rodríguez-Fraticelli, A. E., Peränen, J., Martín-Belmonte, F. and Mostov, K. E. (2010) A molecular network for de novo generation of the apical surface and lumen. Nature Cell Biology, 12(11), pp. 1035-1045. (doi:10.1038/ncb2106)

2008

Bryant, D. M. and Mostov, K. E. (2008) From cells to organs: building polarized tissue. Nature Reviews Molecular Cell Biology, 9(11), pp. 887-901. (doi:10.1038/nrm2523)

Yu, W., Shewan, A. M., Brakeman, P., Eastburn, D. J., Datta, A., Bryant, D. M. , Fan, Q.-W., Weiss, W. A., Zegers, M. M.P. and Mostov, K. E. (2008) Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarity. EMBO Reports, 9(9), pp. 923-929. (doi:10.1038/embor.2008.135)

2007

Bryant, D. and Mostov, K. (2007) Development: inflationary pressures. Nature, 449(7162), pp. 549-550. (doi:10.1038/449549a)

Bryant, D. M. , Kerr, M. C., Hammond, L. A., Joseph, S. R., Mostov, K. E., Teasdale, R. D. and Stow, J. L. (2007) EGF induces macropinocytosis and SNX1-modulated recycling of E-cadherin. Journal of Cell Science, 120(10), pp. 1818-1828. (doi:10.1242/​jcs.000653)

2005

Bryant, D. M., and Stow, J. L. (2005) Nuclear translocation of cell-surface receptors: lessons from fibroblast growth factor. Traffic, 6(10), pp. 947-953. (doi:10.1111/j.1600-0854.2005.00332.x)

Bryant, D. M. , Wylie, F. G. and Stow, J. L. (2005) Regulation of endocytosis, nuclear translocation, and signaling of fibroblast growth factor receptor 1 by E-cadherin. Molecular Biology of the Cell, 16(1), pp. 14-23. (doi:10.1091/mbc.E04-09-0845)

2004

Bryant, D. M. and Stow, J. L. (2004) The ins and outs of E-cadherin trafficking. Trends in Cell Biology, 14(8), pp. 427-34. (doi:10.1016/j.tcb.2004.07.007)

This list was generated on Mon Jun 24 11:20:29 2019 BST.
Jump to: Articles
Number of items: 28.

Articles

Román-Fernández, Á. , Roignot, J., Sandilands, E., Nacke, M., Mansour, M. A., McGarry, L., Shanks, E., Mostov, K. E. and Bryant, D. M. (2018) The phospholipid PI(3,4)P2 is an apical identity determinant. Nature Communications, 9, 5041. (doi:10.1038/s41467-018-07464-8) (PMID:30487552) (PMCID:PMC6262019)

Datta, A., Sandilands, E., Mostov, K. E. and Bryant, D. M. (2017) Fibroblast-derived HGF drives acinar lung cancer cell polarization through integrin-dependent RhoA-ROCK1 inhibition. Cellular Signalling, 40, pp. 91-98. (doi:10.1016/j.cellsig.2017.09.001) (PMID:28888686)

Gao, L., Yang, Z., Hiremath, C., Zimmerman, S. E., Long, B., Brakeman, P. R., Mostov, K. E., Bryant, D. M. , Luby-Phelps, K. and Marciano, D. K. (2017) Developing renal tubules orient cell division via Afadin to position the tubule lumen. Development, 144(19), pp. 3511-3520. (doi:10.1242/dev.148908) (PMID:28860115)

Reid, S. E. et al. (2017) Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium. EMBO Journal, 36(16), pp. 2373-2389. (doi:10.15252/embj.201694912) (PMID:28694244) (PMCID:PMC5556271)

Bryant, D. and Johnson, A. (2017) Meeting report - Intercellular interactions in context: towards a mechanistic understanding of cells in organs. Journal of Cell Science, 130(13), pp. 2083-2085. (doi:10.1242/jcs.205740) (PMID:28738319)

Ruch, T. R., Bryant, D. M. , Mostov, K. E., Engel, J. N. and Yap, A. (2017) Par3 integrates Tiam1 and phosphatidylinositol 3-kinase signaling to change apical membrane identity. Molecular Biology of the Cell, 28(2), pp. 252-260. (doi:10.1091/mbc.E16-07-0541) (PMID:27881661)

Bryant, D. M. and Yap, A. S. (2016) Editorial overview: Membrane traffic and cell polarity. Traffic, 17(12), pp. 1231-1232. (doi:10.1111/tra.12433) (PMID:27885792)

Roman-Fernandez, A. and Bryant, D. M. (2016) Complex polarity: building multicellular tissues through apical membrane traffic. Traffic, 17(12), pp. 1244-1261. (doi:10.1111/tra.12417) (PMID:27281121)

Yang, Z., Zimmerman, S. E., Tsunezumi, J., Braitsch, C., Trent, C., Bryant, D. M. , Cleaver, O., González-Manchón, C. and Marciano, D. K. (2016) Role of CD34 family members in lumen formation in the developing kidney. Developmental Biology, 418(1), pp. 66-74. (doi:10.1016/j.ydbio.2016.08.009) (PMID:27542690)

Overeem, A. W., Bryant, D. M. and van IJzendoorn, S. C.D. (2015) Mechanisms of apical–basal axis orientation and epithelial lumen positioning. Trends in Cell Biology, 25(8), pp. 476-485. (doi:10.1016/j.tcb.2015.04.002) (PMID:25941134)

Bryant, D. M. et al. (2014) A molecular switch for the orientation of epithelial cell polarization. Developmental Cell, 31(2), pp. 171-187. (doi:10.1016/j.devcel.2014.08.027) (PMID:25307480) (PMCID:PMC4248238)

Tran, C. S. et al. (2014) Host cell polarity proteins participate in innate immunity to Pseudomonas aeruginosa infection. Cell Host and Microbe, 15(5), pp. 636-643. (doi:10.1016/j.chom.2014.04.007) (PMID:24832456) (PMCID:PMC4062193)

Apodaca, G., Gallo, L. I. and Bryant, D. M. (2012) Role of membrane traffic in the generation of epithelial cell asymmetry. Nature Cell Biology, 14(12), pp. 1235-1243. (doi:10.1038/ncb2635)

Gálvez-Santisteban, M. et al. (2012) Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells. Nature Cell Biology, 14(8), pp. 838-849. (doi:10.1038/ncb2541) (PMID:22820376) (PMCID:PMC3433678)

Su, T., Chapin, S. J., Bryant, D. M. , Shewan, A. M., Young, K. and Mostov, K. E. (2011) Reduced immunoglobulin A transcytosis associated with immunoglobulin A nephropathy and nasopharyngeal carcinoma. Journal of Biological Chemistry, 286(52), pp. 44921-44925. (doi:10.1074/jbc.M111.296731)

Lepanto, P., Bryant, D. M. , Rossello, J., Datta, A., Mostov, K. E. and Kierbel, A. (2011) Pseudomonas aeruginosa interacts with epithelial cells rapidly forming aggregates that are internalized by a Lyn-dependent mechanism. Cellular Microbiology, 13(8), pp. 1212-1222. (doi:10.1111/j.1462-5822.2011.01611.x)

Marciano, D. K., Brakeman, P. R., Lee, C.-Z., Spivak, N., Eastburn, D. J., Bryant, D. M. , Beaudoin, G. M., Hofmann, I., Mostov, K. E. and Reichardt, L. F. (2011) p120 catenin is required for normal renal tubulogenesis and glomerulogenesis. Development, 138(10), pp. 2099-2109. (doi:10.1242/dev.056564)

Roland, J. T., Bryant, D. M. , Datta, A., Itzen, A., Mostov, K. E. and Goldenring, J. R. (2011) Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization. Proceedings of the National Academy of Sciences of the United States of America, 108(7), pp. 2789-2794. (doi:10.1073/pnas.1010754108)

Datta, A., Bryant, D. M. and Mostov, K. E. (2011) Molecular regulation of lumen morphogenesis. Current Biology, 21(3), R126-R136. (doi:10.1016/j.cub.2010.12.003)

Su, T. et al. (2010) A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor. Nature Cell Biology, 12(12), pp. 1143-1153. (doi:10.1038/ncb2118)

Bryant, D. M. , Datta, A., Rodríguez-Fraticelli, A. E., Peränen, J., Martín-Belmonte, F. and Mostov, K. E. (2010) A molecular network for de novo generation of the apical surface and lumen. Nature Cell Biology, 12(11), pp. 1035-1045. (doi:10.1038/ncb2106)

Bryant, D. M. and Mostov, K. E. (2008) From cells to organs: building polarized tissue. Nature Reviews Molecular Cell Biology, 9(11), pp. 887-901. (doi:10.1038/nrm2523)

Yu, W., Shewan, A. M., Brakeman, P., Eastburn, D. J., Datta, A., Bryant, D. M. , Fan, Q.-W., Weiss, W. A., Zegers, M. M.P. and Mostov, K. E. (2008) Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarity. EMBO Reports, 9(9), pp. 923-929. (doi:10.1038/embor.2008.135)

Bryant, D. and Mostov, K. (2007) Development: inflationary pressures. Nature, 449(7162), pp. 549-550. (doi:10.1038/449549a)

Bryant, D. M. , Kerr, M. C., Hammond, L. A., Joseph, S. R., Mostov, K. E., Teasdale, R. D. and Stow, J. L. (2007) EGF induces macropinocytosis and SNX1-modulated recycling of E-cadherin. Journal of Cell Science, 120(10), pp. 1818-1828. (doi:10.1242/​jcs.000653)

Bryant, D. M., and Stow, J. L. (2005) Nuclear translocation of cell-surface receptors: lessons from fibroblast growth factor. Traffic, 6(10), pp. 947-953. (doi:10.1111/j.1600-0854.2005.00332.x)

Bryant, D. M. , Wylie, F. G. and Stow, J. L. (2005) Regulation of endocytosis, nuclear translocation, and signaling of fibroblast growth factor receptor 1 by E-cadherin. Molecular Biology of the Cell, 16(1), pp. 14-23. (doi:10.1091/mbc.E04-09-0845)

Bryant, D. M. and Stow, J. L. (2004) The ins and outs of E-cadherin trafficking. Trends in Cell Biology, 14(8), pp. 427-34. (doi:10.1016/j.tcb.2004.07.007)

This list was generated on Mon Jun 24 11:20:29 2019 BST.