Professor Richard Reeve
- Professor of Population and Ecosystem Health (Institute of Biodiversity Animal Health & Comparative Medicine)
- Associate (School of Life Sciences)
I am a co-director of the Boyd Orr Centre for Population and Ecosystem Health at the University of Glasgow, where I have been based since coming back into academia in 2007. I am a professor in the Institute of Biodiversity, Animal Health and Comparative Medicine. I am an affiliate PI in the MRC / University of Glasgow Centre for Virus Research and a member of the Glasgow Centre for International Development.
I am a modeller in population and ecosystem health with a background in artificial intelligence and machine learning. I moved into the life sciences in 2007 to study diversity. My work focusses on developing the connections between different fields that use diversity measures, from the level of the transcript to the ecosystem, and the underlying mathematics.
On the application side, I have a particular focus on the measurement of biodiversity of ecosystems, particularly plants, where we work to assemble the spatially and temporally incomplete global data on plant abundance into an understanding of the impact of climate and land use change on species distributions. I currently work on the impact of Landscape Decision making on biodiversity within the UK, working for several years with Peatland ACTION within NatureScot, Scotland's Nature Agency, and more recently beginning similar work with Natural Resources Wales on Welsh peatland restoration.
On the mathematical side, my interests are in the spatial and temporal partitioning of diversity, and how we can identify areas in an ecosystem or viral phenotypes that are novel, that contribute particularly to overall diversity of the system, or that are changing faster than their surroundings.
I also work on how to use measurements of similarity amongst individuals in diversity measures to improve our understanding of the true diversity of different systems - this has led to work with FAO and WHO on the antigenic similarity of viruses, especially foot-and-mouth disease and flu, where I work on the relationship between their genotypic and phenotypic evolution. This has applications in vaccine selection, which is a diversity-related problem, in this case one of maximising the diversity of viruses covered by a specific vaccine.
I also work with colleagues interested in the emergence of antimicrobial resistance phenotypes and genotypes, and how we can identify sources of novel phenotypes from their background diversity or similarity to existing strains, and also on the diversity of the major histocompatibility complex in sheep and cattle, and its relationship to disease resistance.
Much of my work involves the application of mathematical, computational and statistical tools to underexploited biological datasets, particularly focussing on pathogens and vaccines, where large amounts of data are collected on protection for testing purposes which can be reused to investigate vaccine:immune system interaction. I am more generally interested in epidemiological systems and host-pathogen interactions, particularly how they affect our ability to predict the effects of vaccines in the real world.
I have also recently jointly led a COVID-19 consortium, with my focus being particularly on the development of a data pipeline to trace the pathway from FAIR (Findable, Accessible, Interoperable, Resuable) data all the way through to policy advice.
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Open Epidemiology for COVID-19: a transparent, traceable, open source pipeline for reproducible science
2021 - 2022
- Simulating UK plant biodiversity under climate change to aid landscape decision making
2020 - 2022
- Landscape Decisions: Towards a new framework for using land assets programme
2019 - 2020
- Construction of FMDV-specific phage-display libraries and epitope identification for improved FMD vaccines generation
2019 - 2020
- Protecting poultry from avian influenza H5 and H7 virus infections in South East Asia
2018 - 2020
- BBSRC GCRF Fund Impact Accelerator Extension - Boyd Orr
2017 - 2018
- Mathematical Theory and Biological Applications of Diversity
2016 - 2018
- BBSRC IAAF - Boyd Orr Tanzania Research Accelerator
2016 - 2017
- Quinquennial Core Funds
2016 - 2021
- Improving the efficacy of malaria prevention in an insecticide resistant Africa
2016 - 2019
- An effective vaccination programme for the eradication of foot-and-mouth disease from India
2014 - 2017
- The influence of selective breeding on MHC diversity
2014 - 2017
- Assessing the impact of foot-and-mouth disease vaccination programmes
2013 - 2017
- SULSA LEADERS Application
2013 - 2015
- The Mathematics of Biodiversity.
2012 - 2012
- Pirbirght Institute External Research Fellowship
2012 - 2017
- Improving the quality of FMD (Foot-and-mouth disease) vaccines by understanding the correlation of vaccine-induced protection with humoral and cellular inmmune responses
2011 - 2014
- Towards the strategic control of foot-and-mouth disease in Africa: new techniques for a neglected problem
2010 - 2014
- Towards potency by serological assessment - modelling new and archived FMD challenge data from vaccinated cattle
2010 - 2011
- Arnold, Matthew
The Wellcome Trust - Integrative Infection Biology programme