Dr Malcolm Donaldson

Honorary Senior Research Fellow (School of Medicine, Dentistry & Nursing)

email: Malcolm.Donaldson@glasgow.ac.uk

Section of Child Health, University of Glasgow School of Medicine, University Avenue, Glasgow, G12 8QQ

Publications

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Number of items: 76.

2022

Wood, C. L., Morrison, N., Cole, M., Donaldson, M., Dunger, D. B., Wood, R., Pearce, S. H.S. and Cheetham, T. D. (2022) Initial response of young people with thyrotoxicosis to block and replace or dose titration thionamide. European Thyroid Journal, 11(1), e210043. (doi: 10.1530/etj-21-0043) (PMID:34981745) (PMCID:PMC9142802)

2021

McNally, R., Jones, J. H., Shaikh, M. G., Donaldson, M., Blakey, K. and Cheetham, T. (2021) Congenital hypothyroidism: Space-time clustering of thyroid dysgenesis indicates a role for environmental factors in disease etiology. Thyroid, 31(6), pp. 876-883. (doi: 10.1089/thy.2020.0005) (PMID:33183175) (PMCID:PMC8215409)

McVey, L. C., Fletcher, A. , Murtaza, M., Donaldson, M., Wong, S. C. and Mason, A. (2021) Skeletal disproportion in girls with Turner syndrome and longitudinal change with growth promoting therapy. Clinical Endocrinology, 94(5), pp. 797-803. (doi: 10.1111/cen.14413) (PMID:33410185)

2020

Kallali, W., Gray, E., Mehdi, M. Z., Lindsay, R. , Metherell, L. A., Buonocore, F., Suntharalingham, J. P., Achermann, J. C. and Donaldson, M. (2020) Long-term outcome of partial P450 side-chain cleavage enzyme deficiency in three brothers: the importance of early diagnosis. European Journal of Endocrinology, 182(3), K15-K24. (doi: 10.1530/eje-19-0696) (PMID:31917682)

Mansour, C., Ouarezki, Y., Jones, J. H., Green, M., Stenhouse, E. J., Irwin, G., Hermanns, P., Pohlenz, J. and Donaldson, M. D. C. (2020) Determination of thyroid volume in infants with suspected congenital hypothyroidism—the limitations of both subjective and objective evaluation. BJR Open, 2(1), 20200001. (doi: 10.1259/bjro.20200001)

2018

Çizmecioğlu, F. M., Jones, J. H., Forsyth Paterson, W., Kherra, S., Kourime, M., McGowan, R., Shaikh, M. G. and Donaldson, M. (2018) Neonatal features of the Prader-Willi syndrome; the case for making the diagnosis during the first week of life. Journal of Clinical Research in Pediatric Endocrinology, 10(3), pp. 264-273. (doi: 10.4274/jcrpe.0029) (PMID:29553044) (PMCID:PMC6083474)

Kourime, M., McGowan, S., Al Towati, M., Ahmed, S. F. , Stewart, G., Williamson, S., Hunter, I. and Donaldson, M. D.C. (2018) Long-term outcome of thyrotoxicosis in childhood and adolescence in the west of Scotland: the case for long-term antithyroid treatment and the importance of initial counselling. Archives of Disease in Childhood, 103(7), pp. 637-642. (doi: 10.1136/archdischild-2017-313454) (PMID:29269558) (PMCID:PMC6047164)

Bensalah, M. et al. (2018) Cortisol evaluation during the acute phase of traumatic brain injury - a prospective study. Clinical Endocrinology, 88(5), pp. 627-636. (doi: 10.1111/cen.13562) (PMID:29405355)

Ouarezki, Y., Cizmecioglu, F. M., Mansour, C., Jones, J. H., Gault, E. J., Mason, A. and Donaldson, M. (2018) Measured parental height in Turner syndrome—a valuable but underused diagnostic tool. European Journal of Pediatrics, 177(2), pp. 171-179. (doi: 10.1007/s00431-017-3045-2) (PMID:29255949)

2017

Mansour, C., Ouarezki, Y., Jones, J., Fitch, M., Smith, S., Mason, A. and Donaldson, M. (2017) Trends in Scottish newborn screening programme for congenital hypothyroidism 1980-2014: strategies for reducing age at notification after initial and repeat sampling. Archives of Disease in Childhood, 102(10), pp. 936-941. (doi: 10.1136/archdischild-2016-312156) (PMID:28600385)

2016

Pokrovska, T., Jones, J., Shaikh, M. G., Smith, S. and Donaldson, M. D.C. (2016) How well does the capillary thyroid-stimulating hormone test for newborn thyroid screening predict the venous free thyroxine level. Archives of Disease in Childhood, 101(6), pp. 539-545. (doi: 10.1136/archdischild-2015-309529) (PMID:26966265) (PMCID:PMC4893081)

Ahmid, M. et al. (2016) An audit of the management of childhood-onset growth hormone deficiency during young adulthood in Scotland. International Journal of Pediatric Endocrinology, 2016, 6. (doi: 10.1186/s13633-016-0024-8) (PMID:6985190) (PMCID:PMC479349)

2015

Montgomery Sardar, C. , Kinmond, S., Siddique, J., Cooper, A., McGowan, S., Paterson, W., Donnelly, S., Gault, E.J. and Donaldson, M. (2015) Short stature screening by accurate length measurement in infants with a birth weight <9th Centile. Hormone Research in Paediatrics, 83(6), pp. 400-407. (doi: 10.1159/000376611) (PMID:25847071)

McGowan, S., Jones, J., McMillan, D. , McLaughlin, K., Smith, S., Leyland, K., Charleton, P. and Donaldson, M. (2015) Screening for hypothyroidism in Down syndrome using the capillary thyroid stimulating hormone method. Journal of Pediatrics, 166(4), 1013-1017.e2. (doi: 10.1016/j.jpeds.2014.12.035) (PMID:25648292)

Khan, M. J., Humayun, K. N., Donaldson, M., Ahmed, S. F. and Shaikh, M. G. (2015) Longitudinal changes in body mass index in children with craniopharyngioma. Hormone Research in Paediatrics, 82(6), pp. 372-379. (doi: 10.1159/000368798) (PMID:25359623)

Chen, S. C., McDevitt, H., Clement, W. A., Wynne, D. M., Mason, A., Donaldson, M. D.C., Ahmed, S. F. and Shaikh, M. G. (2015) Early identification of pituitary dysfunction in congenital nasal pyriform aperture stenosis: recommendations based on experience in a single centre. Hormone Research in Paediatrics, 83(5), pp. 302-310. (doi: 10.1159/000369805) (PMID:25791686)

2014

Jensen, R.B. et al. (2014) A randomised controlled trial evaluating IGF1 titration in contrast to current GH dosing strategies in children born small for gestational age: the North European Small-for-Gestational-Age Study. European Journal of Endocrinology, 171(4), pp. 509-518. (doi: 10.1530/EJE-14-0419) (PMID:25080293)

Lim, D., Gault, E., Kubba, H., Morrissey, M., Wynne, D. and Donaldson, M. (2014) Cholesteatoma has a high prevalence in Turner syndrome, highlighting the need for earlier diagnosis and the potential benefits of otoscopy training for paediatricians. Acta Paediatrica, 103(7), e282-e287. (doi: 10.1111/apa.12622)

Hermanns, P., Shepherd, S., Mansor, M., Schulga, J., Jones, J., Donaldson, M. and Pohlenz, J. (2014) A new mutation in the promoter region of the PAX8 gene causes true congenital hypothyroidism with thyroid hypoplasia in a girl with Down's syndrome. Thyroid, 24(6), pp. 939-944. (doi: 10.1089/thy.2013.0248)

Perry, R. J., Gault, E.-J., Paterson, W. F., Dunger, D. B. and Donaldson, M. D.C. (2014) Effect of oxandrolone and timing of oral ethinylestradiol initiation on pubertal progression, height velocity and bone maturation in the UK turner study. Hormone Research in Paediatrics, 81(5), pp. 298-308. (doi: 10.1159/000356924)

Sas, T.C.J. et al. (2014) Safety and efficacy of oxandrolone in growth hormone-treated girls with turner syndrome: evidence from recent studies and recommendations for use. Hormone Research in Paediatrics, 81(5), pp. 289-297. (doi: 10.1159/000358195)

Léger, J., Olivieri, A., Donaldson, M., Torresani, T., Krude, H., van Vliet, G., Polak, M. and Butler, G. (2014) European Society for Paediatric Endocrinology Consensus Guidelines on Screening, Diagnosis, and Management of Congenital Hypothyroidism. Hormone Research in Paediatrics, 81(2), pp. 80-103. (doi: 10.1159/000358198)

Lucaccioni, L., Schwahn, B. C., Donaldson, M. and Giacomozzi, C. (2014) Central precocious puberty in a 3 year-old girl with Phenylketonuria: a rare association? BMC Endocrine Disorders, 14, 38. (doi: 10.1186/1472-6823-14-38) (PMID:24773629) (PMCID:PMC4013055)

2013

Donaldson, M. and Jones, J. (2013) Optimising outcome in congenital hypothyroidism; current opinions on best practice in initial assessment and subsequent management. Journal of Clinical Research in Pediatric Endocrinology, 5(S1), pp. 13-21. (doi: 10.4274/Jcrpe.849)

Lucas-Herald, A., Bradley, T., Hermanns, P., Jones, J., Attaie, M., Thompson, E., Pohlenz, J. and Donaldson, M. (2013) Novel heterozygous thyrotropin receptor mutation presenting with neonatal hyperthyrotropinaemia, mild thyroid hypoplasia and absent uptake on radioisotope scan. Journal of Pediatric Endocrinology and Metabolism, 26(5-6), pp. 583-586. (doi: 10.1515/jpem-2012-0308)

2011

Raine, J.E., Donaldson, M.D.C., Gregory, J.W. and van Vliet, G. (2011) Practical endocrinology and diabetes in children. Wiley-Blackwell. ISBN 978-1-4051-9634-5

Gault, E.J., Perry, R.J., Cole, T.J., Casey, S., Paterson, W.M., Hindmarsh, P.J., Betts, P., Dunger, D.B. and Donaldson, M.D.C. (2011) The impact of oxandolone and timing of pubertal induction on final height in Turner sydrome: a randomised, double-blind, placebo-controlled trial. British Medical Journal, 342(d1980), pp. 1-9. (doi: 10.1136/bmj.d1980)

McGowan, S., Jones, J., Brown, A., Reynolds, L., Leyland, K., Charleton, P., Rahim, M., Mansor, M., Ritha, S. and Donaldson, M. (2011) Capillary TSH screening programme for Down's syndrome in Scotland, 1997-2009. Archives of Disease in Childhood, 96(12), pp. 1113-1117. (doi: 10.1136/archdischild-2011-300124)

2010

Connell, N.A., Paterson, W.F., Wallace, A.M. and Donaldson, M.D.C. (2010) Adrenal function and mortality in children and adolescents with Prader-Willi syndrome attending a single centre from 1991-2009. Clinical Endocrinology, 73(5), pp. 686-688. (doi: 10.1111/j.1365-2265.2010.03853.x)

Jones, J.H., Attaie, M., Maroo, S., Neumann, D., Perry, R. and Donaldson, M.D.C. (2010) Heterogeneous tissue in the thyroid fossa on ultrasound in infants with proven thyroid ectopia on isotope scan—a diagnostic trap. Pediatric Radiology, 40(5), pp. 725-731. (doi: 10.1007/s00247-009-1492-2)

Mason, A., McNeill, E., Wallace, A., Connell, J.M. and Donaldson, M.D.C. (2010) Sexual precocity in a 4 year old boy. British Medical Journal, 340, c2319. (doi: 10.1136/bmj.c2319)

Paterson, W.F. et al. (2010) Exaggerated adrenarche in a cohort of Scottish children: clinical features and biochemistry. Clinical Endocrinology, 72(4), pp. 496-501. (doi: 10.1111/j.1365-2265.2009.03739.x)

Andrade, A.C., Baron, J., Manolagas, S.C., Shaw, N.J., Rappold, G.A., Donaldson, M.D.C., Gault, E.J. and Sävendahl, L. (2010) Hormones and genes of importance in bone physiology and their influence on bone mineralization and growth in Turner Syndrome. Hormone Research in Paediatrics, 73(3), pp. 161-165. (doi: 10.1159/000284356)

Cole, T.J., Donaldson, M.D.C. and Ben-Shlomo, Y. (2010) SITAR--a useful instrument for growth curve analysis. International Journal of Epidemiology, 39(6), pp. 1558-1566. (doi: 10.1093/ije/dyq115)

2009

Veeramani, A.K.L., Higgins, P., Butler, S., Donaldson, M.D.C., Dougan, E., Duncan, R., Murday, V. and Ahmed, S.F. (2009) Diagnostic use of skeletal survey in suspected skeletal dysplasia. Journal of Clinical Research in Pediatric Endocrinology, 1(6), p. 270. (doi: 10.4274/jcrpe.v1i6.270)

Gault, E.J. and Donaldson, M.D.C. (2009) Oestrogen replacement in Turner syndrome: current prescribing practice in the UK. Clinical Endocrinology, 71(5), pp. 753-755. (doi: 10.1111/j.1365-2265.2009.03579.x)

Jones, J.H. and Donaldson, M.D.C. (2009) Audit of initial management of congenital hypothyroidism in the United Kingdom--comparison of UK practice with European and UK guidelines. Journal of Pediatric Endocrinology and Metabolism, 22(11), pp. 1017-1025.

Morrison, S.C., Durward, B.R., Watt, G.F. and Donaldson, M.D. (2009) Prediction of anthropometric foot characteristics in children. Journal of the American Podiatric Medical Association, 99(6), pp. 497-502.

Ucar, S.K., Paterson, W.F., Donaldson, M.D.C. and Young, D. (2009) Ethinyl estradiol treatment for growth limitation in girls with Marfan's syndrome--experience from a single center. Endocrine Research, 34(4), pp. 109-120.

2008

Jones, J.H., Gellen, B., Paterson, W.F., Beaton, S. and Donaldson, M.D.C. (2008) Effect of high versus low initial doses of L-thyroxine for congenital hypothyroidism on thyroid function and somatic growth. Archives of Disease in Childhood, 93(11), pp. 940-944. (doi: 10.1136/adc.2007.120618)

Perry, R.J., Ainine, A., Butler, S. and Donaldson, M.D.C. (2008) Hypoechoic thyroid nodules on ultrasound 4 years after prenatal exposure to radioiodine: resolution with thyroxine therapy. Acta Paediatrica, 97(4), pp. 509-512. (doi: 10.1111/j.1651-2227.2008.00725.x)

Hughes, A., Stewart, L., Chapple, J., McColl, J.H. , Donaldson, M.D., Kelnar, C., Zabihollah, M., Ahmed, S.F. and Reilly, J. (2008) Randomized, controlled trial of a best-practice individualized behavioral program for treatment of childhood overweight: Scottish childhood overweight treatment trial (SCOTT). Pediatrics, 121(3), E539-E546. (doi: 10.1542/peds.2007-1786)

Hughes, A.R., Stewart, L., Chapple, J., McColl, J.H. , Donaldson, M.D.C., Kelnar, C.J.H., Zabihollah, M., Ahmed, S.F. and Reilly, J.J. (2008) Randomized, controlled trial of a best-practice individualized behavioral program for treatment of childhood overweight: Scottish childhood overweight treatment trial (SCOTT). Pediatrics, 121(3), e539-e546. (doi: 10.1542/peds.2007-1786)

Morrison, S., Durward, B., Watt, G. and Donaldson, M. (2008) The influence of body mass on the temporal parameters of peripubescent gait. Gait and Posture, 27(4), pp. 719-721.

Popova, G., Paterson, W.F., Brown, A. and Donaldson, M.D.C. (2008) Hashimoto’s Thyroiditis in Down’s Syndrome: Clinical presentation and evolution. Hormone Research in Paediatrics, 70(5), pp. 278-284. (doi: 10.1159/000157874)

2007

Ahmad, I. , Paterson, W.F., Lin, L., Adlard, P., Duncan, P. and Donaldson, M.D.C. (2007) A novel missense mutation in Dax-1 with an unusual presentation of X-linked adrenal hypoplasia congenita. Hormone Research, 68(1), pp. 32-37. (doi: 10.1159/000099835)

Camacho-Hubner, C., Donaldson, M., Dutton, G., Kelly, B., Newman, W., Paterson, W., Savage, M. and Tolmie, J. (2007) Deterioration of visual acuity associated with growth hormone therapy in a child with extreme short stature and high hypermetropia. Hormone Research, 67(2), pp. 67-72.

Donaldson, M.D.C., Morrison, C., Lees, C., McNeill, E., Howatson, A.G., Paton, J.Y. and McWilliam, R. (2007) Fatal and near-fatal encephalopathy with hyponatraemia in two siblings with fluticasone-induced adrenal suppression. Acta Paediatrica, 96(5), pp. 769-772. (doi: 10.1111/j.1651-2227.2007.00251.x)

Donaldson, M., Durward, B., Morrison, S. and Watt, G. (2007) Anthropometric foot structure of peripubescent children with excessive versus normal body mass - A cross-sectional study. Journal of the American Podiatric Medical Association, 97, pp. 366-370.

2006

Beaton, S., Croft, G., Donaldson, M., Jones, J., Mackenzie, J. and Young, D. (2006) Improvement in screening performance and diagnosis of congenital hypothyroidism in Scotland 1979-2003. Archives of Disease in Childhood, 91(8), pp. 680-685.

Beaton, S., Donaldson, M., Galloway, P., Jardine, E., McNeill, E., Paton, J. and Young, D. (2006) Adrenal responses to low dose synthetic ACTH (Synacthen) in children receiving high dose inhaled fluticasone. Archives of Disease in Childhood, 91, pp. 808-813. (doi: 10.1136/adc.2005.087247)

Donaldson, M., Jones, J., Maclennan, A., Maroo, S. and Perry, R. (2006) Combined ultrasound and isotope scanning is more informative in the diagnosis of congenital hypothyroidism than single scanning. Archives of Disease in Childhood, 91(12), pp. 972-976.

Donaldson, M., Kubba, H., Macara, L., Pohlenz, J., Reynolds, B., Simpson, J. and Watt, A. (2006) Goitrous congenital hypothyroidism in a twin pregnancy causing respiratory obstruction at birth: Implications for management. Acta Paediatrica, 95(11), pp. 1345-1348.

Donaldson, M., Dunger, D., Gault, E. and Tan, K. (2006) Optimising management in Turner syndrome: from infancy to adult transfer. Archives of Disease in Childhood, 91, pp. 513-520. (doi: 10.1136/adc.2003.035907)

2005

Abd, A., Donaldson, M., Peterson, P. and Tawfik, S. (2005) Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy presenting with severe keratopathy in an Egyptian patient with a homozygous R139X mutation. Hormone Research, 64, pp. 96-99. (doi: 10.1159/000088307)

Cizmecioglu, F., Doherty, A., Donaldson, M., Paterson, W. and Young, D. (2005) Measured versus reported parental height. Archives of Disease in Childhood, 90(9), pp. 941-942.

Donaldson, M., Murray, P. and Paterson, W. (2005) Maternal age in patients with septo-optic dysplasia. Journal of Pediatric Endocrinology and Metabolism, 18(5), pp. 471-476.

Donaldson, M. and Walley, R. (2005) An investigation of executive function abilities in adults with Prader-Willi syndrome. Journal of Intellectual Disability Research, 49, pp. 613-625.

2004

Donaldson, M., McNeill, E., Paterson, W. and Young, D. (2004) Auxological outcome and time to menarche following long-acting goserelin therapy in girls with central precocious or early puberty. Clinical Endocrinology, 61(5), pp. 626-634.

2003

Donaldson, M., Koppel, D., Longman, C., Paterson, W., Tolmie, J. and Whiteford, M. (2003) Craniosynostosis associated with intracranial calcification: a novel recessive syndrome. Clinical Dysmorphology, 12(4), pp. 215-220.

Donaldson, M. (2003) Cranial MRI scans are indicated in all girls with central precocious puberty - Commentary. Archives of Disease in Childhood, 88(5), pp. 417-418.

Donaldson, M., Kelly, B. and Paterson, W. (2003) Final height outcome and value of height prediction in boys with constitutional delay in growth and adolescence treated with intramuscular testosterone 125 mg per month for 3 months. Clinical Endocrinology, 58(3), pp. 267-272.

Donaldson, M. and Paterson, W. (2003) Growth hormone therapy in the Prader-Willi syndrome. Archives of Disease in Childhood, 88(4), pp. 283-285.

Donaldson, M., Gault, E., Paterson, W. and Young, D. (2003) Improved final height in Turner's syndrome following growth-promoting treatment at a single centre. Acta Paediatrica, 92, pp. 1033-1038. (doi: 10.1080/08035250310004315)

2002

Donaldson, M., Findlay, C. and Perry, R. (2002) Cushing's syndrome, growth impairment, and occult adrenal suppression associated with intranasal steroids. Archives of Disease in Childhood, 87(1), pp. 45-48.

Donaldson, M., Galloway, P., McNeill, E. and Paterson, W. (2002) Safety of the insulin tolerance test. Archives of Disease in Childhood, 87(4), pp. 354-356.

Donaldson, M., Hollman, A. and Paterson, W. (2002) Poor uterine development in Turner syndrome with oral oestrogen therapy. Clinical Endocrinology, 56(3), pp. 359-365.

Donaldson, M., Hollman, A., Perry, R. and Wood, A. (2002) Ultrasound of the thyroid gland in the newborn: normative data. Archives of Disease in Childhood, 87(3), pp. 209-211.

Donaldson, M., Joss, S., Paterson, W. and Tolmie, J. (2002) Cleft palate, hypotelorism, and hypospadias: Schilbach-Rott syndrome. American Journal of Medical Genetics Part A, 113(1), pp. 105-107.

2001

Betts, P., Butler, G., Donaldson, M., Dunger, D., Johnston, D., Kelnar, C., Kirk, J., Price, D. and Wilton, P. (2001) Short stature in Noonan syndrome: response to growth hormone therapy. Archives of Disease in Childhood, 84(5), pp. 440-443. (doi: 10.1136/adc.84.5.440)

Blair, J., Donaldson, M., Hollman, A. and Tolmie, J. (2001) Phenotype, ovarian function, and growth in patients with 45,X/47,XXX Turner mosaicism: Implications for prenatal counseling and estrogen therapy at puberty. Journal of Pediatrics, 139(5), pp. 724-728.

Donaldson, M. (2001) What is the role of growth-hormone therapy in short children who were small for gestational age? Lancet, 358(9279), pp. 347-348.

Donaldson, M. et al. (2001) Procedure for neonatal screening for congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Hormone Research, 55, pp. 201-205.

Donaldson, M., Findlay, C. and Watt, G. (2001) Foot problems in Turner's syndrome. Journal of Pediatrics, 138(5), pp. 775-777.

Donaldson, M., Galloway, P. and Wallace, A. (2001) Sex hormone binding globulin concentration as a prepubertal marker for hyperinsulinaemia in obesity. Archives of Disease in Childhood, 85, pp. 489-491.

1990

Donaldson, M. D.C., Chambers, R. E., Woolridge, M. W. and Whicher, J. T. (1990) Alpha1-microglobulin, beta2-microglobulin and retinol binding protein in childhood febrile illness and renal disease. Pediatric Nephrology, 4(4), pp. 314-318. (doi: 10.1007/BF00862506) (PMID:1698438)

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