Dr Zhenbo Cao
- Research Associate (Molecular Biosciences)
telephone:
6453
email:
Zhenbo.Cao@glasgow.ac.uk
Lab 232, Davidson Building, Glasgow, G12 8QQ
Publications
2022
Oka, Ojore Benedict Valentine ORCID: https://orcid.org/0000-0003-3482-115X, Pierre, Arvin Shedrach, Pringle, Marie Anne
ORCID: https://orcid.org/0000-0002-1358-4610, Tungkum, Wanida, Cao, Zhenbo, Fleming, Bethany and Bulleid, Neil John
ORCID: https://orcid.org/0000-0002-9839-5279
(2022)
Activation of the UPR sensor ATF6α is regulated by its redox-dependent dimerization and ER retention by ERp18.
Proceedings of the National Academy of Sciences of the United States of America, 119(12),
e2122657119.
(doi: 10.1073/pnas.2122657119)
(PMID:35286189)
(PMCID:PMC8944254)
2020
Javitt, Gabriel, Cao, Zhenbo, Resnick, Efrat, Gabizon, Ronen, Bulleid, Neil ORCID: https://orcid.org/0000-0002-9839-5279 and Fass, Deborah
(2020)
Structure and electron-transfer pathway of the human methionine sulfoxide reductase MsrB3.
Antioxidants and Redox Signaling, 33(10),
pp. 665-678.
(doi: 10.1089/ars.2020.8037)
(PMID:32517586)
(PMCID:PMC7475093)
Cao, Xiaofei, Lilla, Sergio, Cao, Zhenbo, Pringle, Marie Anne, Oka, Ojore B.V. ORCID: https://orcid.org/0000-0003-3482-115X, Robinson, Philip J.
ORCID: https://orcid.org/0000-0003-2576-5010, Szmaja, Tomasz, Van Lith, Marcel, Zanivan, Sara and Bulleid, Neil
ORCID: https://orcid.org/0000-0002-9839-5279
(2020)
The mammalian cytosolic thioredoxin reductase pathway acts via a membrane 1 protein to reduce ER-localised proteins.
Journal of Cell Science, 133,
jcs241976.
(doi: 10.1242/jcs.241976)
(PMID:32184267)
(PMCID:PMC7197872)
2018
De Lucca Camargo, L. et al. (2018) Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension. Hypertension, 72(1), pp. 235-246. (doi: 10.1161/HYPERTENSIONAHA.118.10824) (PMID:29844144) (PMCID:PMC6004120)
Cao, Zhenbo, Mitchell, Lorna, Hsia, Oliver, Scarpa, Miriam, Caldwell, Stuart T. ORCID: https://orcid.org/0000-0003-1604-3462, Alfred, Arina D., Gennaris, Alexandra, Collet, Jean-Francois, Hartley, Richard C.
ORCID: https://orcid.org/0000-0003-1033-5405 and Bulleid, Neil J.
ORCID: https://orcid.org/0000-0002-9839-5279
(2018)
Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase.
Biochemical Journal, 475,
pp. 827-838.
(doi: 10.1042/BCJ20170929)
(PMID:29420254)
(PMCID:PMC6488974)
2017
De Lucca Camargo, Livia ORCID: https://orcid.org/0000-0002-7451-7147, Cesar Montezano, Augusto, Tsiropoulou, Sofia, Harvey, Adam, Hood, Katie, Cao, Zhenbo, Burchmore, Richard
ORCID: https://orcid.org/0000-0003-1663-9004, Bulleid, Neil
ORCID: https://orcid.org/0000-0002-9839-5279 and Touyz, Rhian
ORCID: https://orcid.org/0000-0003-0670-0887
(2017)
181 Nox compartmentalization and protein oxidation in vascular smooth muscle cells – implications in vascular dysfunction in hypertension.
Heart, 103(Suppl),
A125.1-A125.
(doi: 10.1136/heartjnl-2017-311726.179)
Poet, Greg J., Oka, Ojore B.V. ORCID: https://orcid.org/0000-0003-3482-115X, Van Lith, Marcel, Cao, Zhenbo, Robinson, Philip J.
ORCID: https://orcid.org/0000-0003-2576-5010, Pringle, Marie Anne
ORCID: https://orcid.org/0000-0002-1358-4610, Arnér, Elias S.J. and Bulleid, Neil
ORCID: https://orcid.org/0000-0002-9839-5279
(2017)
Cytosolic thioredoxin reductase 1 is required for correct disulfide formation in the ER.
EMBO Journal, 36(5),
pp. 693-702.
(doi: 10.15252/embj.201695336)
(PMID:28093500)
(PMCID:PMC5331760)
Cao, Zhenbo and Lindsay, John Gordon (2017) The peroxiredoxin family: an unfolding story. In: Harris, J. Robin and Marles-Wright, Jon (eds.) Macromolecular Protein Complexes. Series: Subcellular biochemistry (82). Springer, pp. 127-147. ISBN 9783319465012 (doi: 10.1007/978-3-319-46503-6_5)
2016
Cao, Zhenbo, Van Lith, Marcel, Mitchell, Lorna J., Pringle, Marie Anne ORCID: https://orcid.org/0000-0002-1358-4610, Inaba, Kenji and Bulleid, Neil J.
ORCID: https://orcid.org/0000-0002-9839-5279
(2016)
The membrane topology of vitamin K epoxide reductase is conserved between human isoforms and the bacterial enzyme.
Biochemical Journal, 473(7),
pp. 851-858.
(doi: 10.1042/bj20151223)
(PMID:26772871)
2015
Cao, Zhenbo and Bulleid, Neil J. ORCID: https://orcid.org/0000-0002-9839-5279
(2015)
Detecting peroxiredoxin hyperoxidation by one-dimensional isoelectric focusing.
Biophysics Reports, 1(1),
pp. 14-17.
(doi: 10.1007/s41048-015-0007-y)
(PMID:26942215)
(PMCID:PMC4762124)
Cao, Zhenbo, McGow, Donna P., Shepherd, Colin and Lindsay, J. Gordon (2015) Improved catenated structures of bovine peroxiredoxin III F190L reveal details of ring-ring interactions and a novel conformational state. PLoS ONE, 10(4), e0123303. (doi: 10.1371/journal.pone.0123303) (PMID:25906064) (PMCID:PMC4407889)
2014
Cao, Zhenbo, Subramaniam, Suraj and Bulleid, Neil J. ORCID: https://orcid.org/0000-0002-9839-5279
(2014)
Lack of an efficient endoplasmic reticulum-localized recycling system protects peroxiredoxin IV from hyperoxidation.
Journal of Biological Chemistry, 289(9),
pp. 5490-5498.
(doi: 10.1074/jbc.M113.529305)
Martin, Rachel E., Cao, Zhenbo and Bulleid, Neil J. ORCID: https://orcid.org/0000-0002-9839-5279
(2014)
Regulating the level of intracellular hydrogen peroxide: the role of peroxiredoxin IV.
Biochemical Society Transactions, 42(1),
pp. 42-46.
(doi: 10.1042/BST20130168)
2011
Cao, Z., Tavender, T.J., Roszak, A.W., Cogdell, R.J. ORCID: https://orcid.org/0000-0003-2119-6607 and Bulleid, N.J.
ORCID: https://orcid.org/0000-0002-9839-5279
(2011)
Crystal structure of reduced and of oxidized peroxiredoxin IV enzyme reveals a stable oxidized decamer and a non-disulfide-bonded intermediate in the catalytic cycle.
Journal of Biological Chemistry, 286(49),
pp. 42257-42266.
(doi: 10.1074/jbc.M111.298810)
2007
Cao, Z., Bhella, D. ORCID: https://orcid.org/0000-0003-2096-8310 and Lindsay, J.G.
(2007)
Reconstitution of the mitochondrial PrxII antioxidant defence pathway: General properties and factors affecting PrxII activity and oligomeric state.
Journal of Molecular Biology, 372,
pp. 1022-1033.
(doi: 10.1016/j.jmb.2007.07.018)
2005
Cao, Z.B., Roszak, A.W., Gourlay, L.J., Lindsay, J.G. and Isaacs, N.W. (2005) Bovine mitochondrial peroxiredoxin III forms a two-ring catenane. Structure, 13(11), pp. 1661-1664. (doi: 10.1016/i.str.2005.07.021)
Articles
Oka, Ojore Benedict Valentine ORCID: https://orcid.org/0000-0003-3482-115X, Pierre, Arvin Shedrach, Pringle, Marie Anne
ORCID: https://orcid.org/0000-0002-1358-4610, Tungkum, Wanida, Cao, Zhenbo, Fleming, Bethany and Bulleid, Neil John
ORCID: https://orcid.org/0000-0002-9839-5279
(2022)
Activation of the UPR sensor ATF6α is regulated by its redox-dependent dimerization and ER retention by ERp18.
Proceedings of the National Academy of Sciences of the United States of America, 119(12),
e2122657119.
(doi: 10.1073/pnas.2122657119)
(PMID:35286189)
(PMCID:PMC8944254)
Javitt, Gabriel, Cao, Zhenbo, Resnick, Efrat, Gabizon, Ronen, Bulleid, Neil ORCID: https://orcid.org/0000-0002-9839-5279 and Fass, Deborah
(2020)
Structure and electron-transfer pathway of the human methionine sulfoxide reductase MsrB3.
Antioxidants and Redox Signaling, 33(10),
pp. 665-678.
(doi: 10.1089/ars.2020.8037)
(PMID:32517586)
(PMCID:PMC7475093)
Cao, Xiaofei, Lilla, Sergio, Cao, Zhenbo, Pringle, Marie Anne, Oka, Ojore B.V. ORCID: https://orcid.org/0000-0003-3482-115X, Robinson, Philip J.
ORCID: https://orcid.org/0000-0003-2576-5010, Szmaja, Tomasz, Van Lith, Marcel, Zanivan, Sara and Bulleid, Neil
ORCID: https://orcid.org/0000-0002-9839-5279
(2020)
The mammalian cytosolic thioredoxin reductase pathway acts via a membrane 1 protein to reduce ER-localised proteins.
Journal of Cell Science, 133,
jcs241976.
(doi: 10.1242/jcs.241976)
(PMID:32184267)
(PMCID:PMC7197872)
De Lucca Camargo, L. et al. (2018) Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension. Hypertension, 72(1), pp. 235-246. (doi: 10.1161/HYPERTENSIONAHA.118.10824) (PMID:29844144) (PMCID:PMC6004120)
Cao, Zhenbo, Mitchell, Lorna, Hsia, Oliver, Scarpa, Miriam, Caldwell, Stuart T. ORCID: https://orcid.org/0000-0003-1604-3462, Alfred, Arina D., Gennaris, Alexandra, Collet, Jean-Francois, Hartley, Richard C.
ORCID: https://orcid.org/0000-0003-1033-5405 and Bulleid, Neil J.
ORCID: https://orcid.org/0000-0002-9839-5279
(2018)
Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase.
Biochemical Journal, 475,
pp. 827-838.
(doi: 10.1042/BCJ20170929)
(PMID:29420254)
(PMCID:PMC6488974)
De Lucca Camargo, Livia ORCID: https://orcid.org/0000-0002-7451-7147, Cesar Montezano, Augusto, Tsiropoulou, Sofia, Harvey, Adam, Hood, Katie, Cao, Zhenbo, Burchmore, Richard
ORCID: https://orcid.org/0000-0003-1663-9004, Bulleid, Neil
ORCID: https://orcid.org/0000-0002-9839-5279 and Touyz, Rhian
ORCID: https://orcid.org/0000-0003-0670-0887
(2017)
181 Nox compartmentalization and protein oxidation in vascular smooth muscle cells – implications in vascular dysfunction in hypertension.
Heart, 103(Suppl),
A125.1-A125.
(doi: 10.1136/heartjnl-2017-311726.179)
Poet, Greg J., Oka, Ojore B.V. ORCID: https://orcid.org/0000-0003-3482-115X, Van Lith, Marcel, Cao, Zhenbo, Robinson, Philip J.
ORCID: https://orcid.org/0000-0003-2576-5010, Pringle, Marie Anne
ORCID: https://orcid.org/0000-0002-1358-4610, Arnér, Elias S.J. and Bulleid, Neil
ORCID: https://orcid.org/0000-0002-9839-5279
(2017)
Cytosolic thioredoxin reductase 1 is required for correct disulfide formation in the ER.
EMBO Journal, 36(5),
pp. 693-702.
(doi: 10.15252/embj.201695336)
(PMID:28093500)
(PMCID:PMC5331760)
Cao, Zhenbo, Van Lith, Marcel, Mitchell, Lorna J., Pringle, Marie Anne ORCID: https://orcid.org/0000-0002-1358-4610, Inaba, Kenji and Bulleid, Neil J.
ORCID: https://orcid.org/0000-0002-9839-5279
(2016)
The membrane topology of vitamin K epoxide reductase is conserved between human isoforms and the bacterial enzyme.
Biochemical Journal, 473(7),
pp. 851-858.
(doi: 10.1042/bj20151223)
(PMID:26772871)
Cao, Zhenbo and Bulleid, Neil J. ORCID: https://orcid.org/0000-0002-9839-5279
(2015)
Detecting peroxiredoxin hyperoxidation by one-dimensional isoelectric focusing.
Biophysics Reports, 1(1),
pp. 14-17.
(doi: 10.1007/s41048-015-0007-y)
(PMID:26942215)
(PMCID:PMC4762124)
Cao, Zhenbo, McGow, Donna P., Shepherd, Colin and Lindsay, J. Gordon (2015) Improved catenated structures of bovine peroxiredoxin III F190L reveal details of ring-ring interactions and a novel conformational state. PLoS ONE, 10(4), e0123303. (doi: 10.1371/journal.pone.0123303) (PMID:25906064) (PMCID:PMC4407889)
Cao, Zhenbo, Subramaniam, Suraj and Bulleid, Neil J. ORCID: https://orcid.org/0000-0002-9839-5279
(2014)
Lack of an efficient endoplasmic reticulum-localized recycling system protects peroxiredoxin IV from hyperoxidation.
Journal of Biological Chemistry, 289(9),
pp. 5490-5498.
(doi: 10.1074/jbc.M113.529305)
Martin, Rachel E., Cao, Zhenbo and Bulleid, Neil J. ORCID: https://orcid.org/0000-0002-9839-5279
(2014)
Regulating the level of intracellular hydrogen peroxide: the role of peroxiredoxin IV.
Biochemical Society Transactions, 42(1),
pp. 42-46.
(doi: 10.1042/BST20130168)
Cao, Z., Tavender, T.J., Roszak, A.W., Cogdell, R.J. ORCID: https://orcid.org/0000-0003-2119-6607 and Bulleid, N.J.
ORCID: https://orcid.org/0000-0002-9839-5279
(2011)
Crystal structure of reduced and of oxidized peroxiredoxin IV enzyme reveals a stable oxidized decamer and a non-disulfide-bonded intermediate in the catalytic cycle.
Journal of Biological Chemistry, 286(49),
pp. 42257-42266.
(doi: 10.1074/jbc.M111.298810)
Cao, Z., Bhella, D. ORCID: https://orcid.org/0000-0003-2096-8310 and Lindsay, J.G.
(2007)
Reconstitution of the mitochondrial PrxII antioxidant defence pathway: General properties and factors affecting PrxII activity and oligomeric state.
Journal of Molecular Biology, 372,
pp. 1022-1033.
(doi: 10.1016/j.jmb.2007.07.018)
Cao, Z.B., Roszak, A.W., Gourlay, L.J., Lindsay, J.G. and Isaacs, N.W. (2005) Bovine mitochondrial peroxiredoxin III forms a two-ring catenane. Structure, 13(11), pp. 1661-1664. (doi: 10.1016/i.str.2005.07.021)
Book Sections
Cao, Zhenbo and Lindsay, John Gordon (2017) The peroxiredoxin family: an unfolding story. In: Harris, J. Robin and Marles-Wright, Jon (eds.) Macromolecular Protein Complexes. Series: Subcellular biochemistry (82). Springer, pp. 127-147. ISBN 9783319465012 (doi: 10.1007/978-3-319-46503-6_5)