Dr Thimo Kurz

Honorary Senior Lecturer (School of Molecular Biosciences)

University of Glasgow, Davidson Building, Lab 241, G12 8QQ

Publications

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Jump to: 2024 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2006 | 2005 | 2003 | 2002

Number of items: 28.

2024

Ayuso-García, P. et al. (2024) Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination. Science Advances, 10(15), eadm7600. (doi: 10.1126/sciadv.adm7600) (PMID:38608019) (PMCID:PMC11014456)

2019

Keuss, Matthew J., Hjerpe, Roland, Hsia, Oliver, Gourlay, Robert, Burchmore, Richard ORCID: https://orcid.org/0000-0003-1663-9004, Trost, Matthias and Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 (2019) Unanchored tri-NEDD8 inhibits PARP-1 to protect from oxidative stress-induced cell death. EMBO Journal, 38, e100024. (doi: 10.15252/embj.2018100024) (PMID:30804002) (PMCID:PMC6418418)

2018

Thomas, Yann, Scott, Daniel C., Kristariyanto, Yosua Adi, Rinehart, Jesse, Clark, Kristopher, Cohen, Philip and Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 (2018) The NEDD8 E3 ligase DCNL5 is phosphorylated by IKK alpha during Toll-like receptor activation. PLoS ONE, 13(6), e0199197. (doi: 10.1371/journal.pone.0199197) (PMID:29958295) (PMCID:PMC6025869)

2017

Murthy, Meena, Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 and O'Shaughnessy, Kevin M. (2017) WNK signalling pathways in blood pressure regulation. Cellular and Molecular Life Sciences, 74(7), pp. 1261-1280. (doi: 10.1007/s00018-016-2402-z) (PMID:27815594) (PMCID:PMC5346417)

2016

Schumacher, Frances-Rose, Schubert, Steffen, Hannus, Michael, Sönnichsen, Birte, Ittrich, Carina, Kreideweiss, Stefan, Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 and Rippmann, Jörg F. (2016) RNAi screen for NRF2 inducers identifies targets that rescue primary lung epithelial cells from cigarette smoke induced radical stress. PLoS ONE, 11(11), e0166352. (doi: 10.1371/journal.pone.0166352) (PMID:27832175) (PMCID:PMC5104413)

Hjerpe, R. et al. (2016) UBQLN2 mediates autophagy-independent protein aggregate clearance by the proteasome. Cell, 166(4), pp. 935-949. (doi: 10.1016/j.cell.2016.07.001) (PMID:27477512) (PMCID:PMC5003816)

Murthy, Meena, Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 and O'Shaughnessy, Kevin M. (2016) ROMK expression remains unaltered in a mouse model of familial hyperkalemic hypertension caused by the CUL3Δ403‐459mutation. Physiological Reports, 4(13), e12850. (doi: 10.14814/phy2.12850) (PMID:27378813) (PMCID:PMC4945836)

Keuss, Matthew J., Thomas, Yann, Mcarthur, Robert, Wood, Nicola T., Knebel, Axel and Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 (2016) Characterisation of the mammalian family of DCN-type NEDD8 E3 ligases. Journal of Cell Science, 129(7), pp. 1441-1454. (doi: 10.1242/jcs.181784) (PMID:26906416)

2015

Schumacher, F.-R. et al. (2015) Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia. EMBO Molecular Medicine, 7(10), pp. 1285-1306. (doi: 10.15252/emmm.201505444) (PMID:26286618) (PMCID:PMC4604684)

Meir, M. et al. (2015) The COP9 signalosome is vital for timely repair of DNA double-strand breaks. Nucleic Acids Research, 43(9), pp. 4517-4530. (doi: 10.1093/nar/gkv270) (PMID:25855810) (PMCID:PMC4482063)

Bett, J.S. et al. (2015) Ubiquitin-C-terminal hydrolases cleave isopeptide and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers. Biochemical Journal, 466(3), pp. 489-498. (doi: 10.1042/BJ20141349) (PMID:25489924) (PMCID:PMC4353193)

2014

Schumacher, Frances-Rose, Sorrell, Fiona J., Alessi, Dario R., Bullock, Alex N. and Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 (2014) Structural and biochemical characterization of the KLHL3–WNK kinase interaction important in blood pressure regulation. Biochemical Journal, 460(2), pp. 237-246. (doi: 10.1042/BJ20140153) (PMID:24641320) (PMCID:PMC4019986)

2013

Ohta, Akihito, Schumacher, Frances-Rose, Mehellou, Youcef, Johnson, Clare, Knebel, Axel, Macartney, Thomas J., Wood, Nicola T., Alessi, Dario R. and Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 (2013) The CUL3–KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction. Biochemical Journal, 451(1), pp. 111-122. (doi: 10.1042/BJ20121903) (PMID:23387299) (PMCID:PMC3632089)

Zemla, Aleksandra, Thomas, Yann, Kedziora, Sylwia, Knebel, Axel, Wood, Nicola T., Rabut, Gwenaël and Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 (2013) CSN- and CAND1-dependent remodelling of the budding yeast SCF complex. Nature Communications, 4, 1641. (doi: 10.1038/ncomms2628) (PMID:23535662)

2012

Lee, David Wei, Peggie, Mark, Deak, Maria, Toth, Rachel, Gage, Zoe Olivia, Wood, Nicola, Schilde, Christina, Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 and Knebel, Axel (2012) The Dac-tag, an affinity tag based on penicillin-binding protein 5. Analytical Biochemistry, 428(1), pp. 64-72. (doi: 10.1016/j.ab.2012.06.007) (PMID:22705378)

Hjerpe, Roland, Thomas, Yann and Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 (2012) NEDD8 overexpression results in neddylation of ubiquitin substrates by the ubiquitin pathway. Journal of Molecular Biology, 421(1), pp. 27-29. (doi: 10.1016/j.jmb.2012.05.013) (PMID:22608973)

Hjerpe, Roland, Thomas, Yann, Chen, Jesse, Zemla, Aleksandra, Curran, Siobhan, Shpiro, Natalia, Dick, Lawrence R. and Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 (2012) Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes. Biochemical Journal, 441(3), pp. 927-939. (doi: 10.1042/BJ20111671) (PMID:22004789) (PMCID:PMC3280039)

2011

Rabut, Gwenaël, Le Dez, Gaëlle, Verma, Rati, Makhnevych, Taras, Knebel, Axel, Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993, Boone, Charles, Deshaies, Raymond J. and Peter, Matthias (2011) The TFIIH subunit Tfb3 regulates cullin neddylation. Molecular Cell, 43(3), pp. 488-495. (doi: 10.1016/j.molcel.2011.05.032) (PMID:21816351) (PMCID:PMC3186349)

2010

Scott, Daniel C., Monda, Julie K., Grace, Christy R.R., Duda, David M., Kriwacki, Richard W., Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 and Schulman, Brenda A. (2010) A Dual E3 mechanism for Rub1 ligation to Cdc53. Molecular Cell, 39(5), pp. 784-796. (doi: 10.1016/j.molcel.2010.08.030) (PMID:20832729) (PMCID:PMC3001161)

2009

Siergiejuk, Edyta, Scott, Daniel C., Schulman, Brenda A., Hofmann, Kay, Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 and Peter, Matthias (2009) Cullin neddylation and substrate-adaptors counteract SCF inhibition by the CAND1-like protein Lag2 in Saccharomyces cerevisiae. EMBO Journal, 28(24), pp. 3845-3856. (doi: 10.1038/emboj.2009.354) (PMID:19942853) (PMCID:PMC2797064)

Meyer-Schaller, Nathalie, Chou, Yang-Chieh, Sumara, Izabela, Martin, Dale D.O., Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993, Katheder, Nadja, Hofmann, Kay, Berthiaume, Luc G., Sicheri, Frank and Peter, Matthias (2009) The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes. Proceedings of the National Academy of Sciences of the United States of America, 106(30), pp. 12365-12370. (doi: 10.1073/pnas.0812528106) (PMID:19617556) (PMCID:PMC2718329)

2008

Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993, Chou, Yang-Chieh, Willems, Andrew R., Meyer-Schaller, Nathalie, Hecht, Marie-Lyn, Tyers, Mike, Peter, Matthias and Sicheri, Frank (2008) Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation. Molecular Cell, 29(1), pp. 23-35. (doi: 10.1016/j.molcel.2007.12.012) (PMID:18206966)

2006

Luke, Brian, Versini, Gwennaelle, Jaquenoud, Malika, Zaidi, Iram Waris, Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993, Pintard, Lionel, Pasero, Philippe and Peter, Matthias (2006) The cullin Rtt101p promotes replication fork progression through damaged DNA and natural pause sites. Current Biology, 16(8), pp. 786-792. (doi: 10.1016/j.cub.2006.02.071) (PMID:16631586)

Bowerman, Bruce and Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993 (2006) Degrade to create: developmental requirements for ubiquitin-mediated proteolysis during early C. elegans embryogenesis. Development, 133(5), pp. 773-784. (doi: 10.1242/dev.02276) (PMID:16469970)

2005

Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993, Özlü, Nurhan, Rudolf, Fabian, O'Rourke, Sean M., Luke, Brian, Hofmann, Kay, Hyman, Anthony A., Bowerman, Bruce and Peter, Matthias (2005) The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature, 435(7046), pp. 1257-1261. (doi: 10.1038/nature03662) (PMID:15988528)

2003

Pintard, L. et al. (2003) The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase. Nature, 425(6955), pp. 311-316. (doi: 10.1038/nature01959) (PMID:13679921)

Pintard, Lionel, Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993, Glaser, Sarah, Willis, John H., Peter, Matthias and Bowerman, Bruce (2003) Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans. Current Biology, 13(11), pp. 911-921. (doi: 10.1016/S0960-9822(03)00336-1) (PMID:12781129)

2002

Kurz, Thimo ORCID: https://orcid.org/0000-0003-0700-6993, Pintard, Lionel, Willis, John H., Hamill, Danielle R., Gönczy, Pierre, Peter, Matthias and Bowerman, Bruce (2002) Cytoskeletal regulation by the Nedd8 ubiquitin-like protein modification pathway. Science, 295(5558), pp. 1294-1298. (doi: 10.1126/science.1067765) (PMID:11847342)

This list was generated on Sun Jun 15 11:04:05 2025 BST.

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