Dr Sharon Kelly
- Honorary Senior Research Fellow (School of Molecular Biosciences)
                        email: 
                        Sharon.Kelly@glasgow.ac.uk
                    
School of Molecular Biosciences, CMVLS, Joseph Black Bldg, University of Glasgow, G12 8QQ
Research interests
Manager of the Protein Characterisation Facility. Involved with collaborative studies encompassing the following main themes: protein structure and folding; protein-protein interactions; protein-ligand interactions; and protein-DNA interactions
Publications
2024
    
    Raynes, Jared K, Mata, Jitendra, Wilde, Karyn L, Carver, John A, Kelly, Sharon M. ORCID: https://orcid.org/0000-0002-3516-1387 and Holt, Carl 
ORCID: https://orcid.org/0000-0002-2087-1546
  
(2024)
  
Structure of biomimetic casein micelles: critical tests of the hydrophobic colloid and multivalent-binding models using recombinant deuterated and phosphorylated β-casein.
    
    Journal of Structural Biology: X, 9,
	 
      100096.
    
    (doi: 10.1016/j.yjsbx.2024.100096)
    (PMID:38318529) 
    (PMCID:PMC10840362) 
  
  
2022
    
    Zahid, Henna, Lau, Andy M., Kelly, Sharon M. ORCID: https://orcid.org/0000-0002-3516-1387, Karu, Kersti, Gor, Jayesh, Perkins, Stephen J. and McDermott, Lindsay C.
  
(2022)
  
Identification of diverse lipid‐binding modes in the groove of zinc α2 glycoprotein reveals its functional versatility.
    
    FEBS Journal, 289(7),
	  pp. 1876-1896.
     
    
    (doi: 10.1111/febs.16293)
    (PMID:34817923) 
     
  
  
    
    Neckebroeck, Albane, Kelly, Sharon M. ORCID: https://orcid.org/0000-0002-3516-1387, Smith, Brian O. 
ORCID: https://orcid.org/0000-0003-3363-4168 and Clark, J. Stephen 
ORCID: https://orcid.org/0000-0003-3935-0377
  
(2022)
  
Synthesis of the prototypical cyclopropyl dipeptide mimic and evaluation of its turn-inducing capability.
    
    Journal of Organic Chemistry, 87(1),
	  pp. 258-270.
     
    
    (doi: 10.1021/acs.joc.1c02344)
    (PMID:34913698) 
     
  
  
2019
Debnath, S. et al. (2019) Tunable supramolecular gels by varying thermal history. Chemistry: A European Journal, 25(33), pp. 7881-7887. (doi: 10.1002/chem.201806281) (PMID:30945773)
Tabudravu, J. N. et al. (2019) LC-HRMS-database screening metrics for rapid prioritization of samples to accelerate the discovery of structurally new natural products. Journal of Natural Products, 82(2), pp. 211-220. (doi: 10.1021/acs.jnatprod.8b00575) (PMID:30735391)
2018
    
    Southall, June ORCID: https://orcid.org/0000-0002-5496-1531, Henry, Sarah L., Gardiner, Alastair T., Roszak, Aleksander W., Mullen, William 
ORCID: https://orcid.org/0000-0002-5685-1563, Carey, Anne-Marie, Kelly, Sharon M. 
ORCID: https://orcid.org/0000-0002-3516-1387, de Percin Northumberland, Claire Ortmann and Cogdell, Richard J. 
ORCID: https://orcid.org/0000-0003-2119-6607
  
(2018)
  
Characterisation of a pucBA deletion mutant from Rhodopseudomonas palustris lacking all but the pucBAd genes.
    
    Photosynthesis Research, 135(1-3),
	  pp. 9-21.
     
    
    (doi: 10.1007/s11120-017-0386-7)
    (PMID:28567613) 
     
  
  
    
    Pages, Benjamin J., Sakoff, Jennette, Gilbert, Jayne, Zhang, Yingjie, Kelly, Sharon M. ORCID: https://orcid.org/0000-0002-3516-1387, Hoeschele, James D. and Aldrich-Wright, Janice R.
  
(2018)
  
Combining the platinum(ii) drug candidate kiteplatin with 1,10-phenanthroline analogues.
    
    Dalton Transactions, 47(7),
	  pp. 2101-2472.
     
    
    (doi: 10.1039/c7dt04108j)
    (PMID:29192713) 
     
  
  
2017
    
    Petersen, Jan, Inoue, Shin-ichiro, Kelly, Sharon M. ORCID: https://orcid.org/0000-0002-3516-1387, Sullivan, Stuart 
ORCID: https://orcid.org/0000-0002-1042-7855, Kinoshita, Toshinori and Christie, John M. 
ORCID: https://orcid.org/0000-0002-9976-0055
  
(2017)
  
Functional characterization of a constitutively active kinase variant of Arabidopsis phototropin 1.
    
    Journal of Biological Chemistry, 292(33),
	  pp. 13843-13852.
     
    
    (doi: 10.1074/jbc.M117.799643)
    (PMID:28663371) 
    (PMCID:PMC5566536) 
  
  
    
    Kulikov, Vladislav, Johnson, Naomi A.B., Surman, Andrew J. ORCID: https://orcid.org/0000-0002-2042-7373, Hutin, Marie, Kelly, Sharon K. 
ORCID: https://orcid.org/0000-0002-3516-1387, Hezwani, Mohammed, Long, De-Liang 
ORCID: https://orcid.org/0000-0003-3241-2379, Meyer, Gerd and Cronin, Leroy 
ORCID: https://orcid.org/0000-0001-8035-5757
  
(2017)
  
Spontaneous assembly of an organic-inorganic nucleic acid Z-DNA double-helix structure.
    
    Angewandte Chemie (International Edition), 56(4),
	  pp. 1141-1145.
     
    
    (doi: 10.1002/anie.201606658)
    (PMID:27900812) 
    (PMCID:PMC6057607) 
  
  
2016
    
    Cupellini, Lorenzo, Jurinovich, Sandro, Campetella, Marco, Caprasecca, Stefano, Guido, Ciro A., Kelly, Sharon M. ORCID: https://orcid.org/0000-0002-3516-1387, Gardiner, Alastair T., Cogdell, Richard 
ORCID: https://orcid.org/0000-0003-2119-6607 and Mennucci, Benedetta
  
(2016)
  
An Ab Initio description of the excitonic properties of LH2 and their temperature dependence.
    
    Journal of Physical Chemistry B, 120(44),
	  pp. 11348-11359.
     
    
    (doi: 10.1021/acs.jpcb.6b06585)
    (PMID:27791372) 
     
  
  
Grinter, R. et al. (2016) Structure of the bacterial plant-ferredoxin receptor FusA. Nature Communications, 7, 13308. (doi: 10.1038/ncomms13308) (PMID:27796364) (PMCID:PMC5095587)
    
    Pages, Benjamin J., Sakoff, Jennette, Gilbert, Jayne, Rodger, Alison, Chmel, Nikola P., Jones, Nykola C., Kelly, Sharon M. ORCID: https://orcid.org/0000-0002-3516-1387, Ang, Dale L. and Aldrich-Wright, Janice R.
  
(2016)
  
Multifaceted studies of the DNA interactions and In vitro cytotoxicity of anticancer polyaromatic platinum(II) complexes.
    
    Chemistry: A European Journal, 22(26),
	  pp. 8943-8954.
     
    
    (doi: 10.1002/chem.201601221)
    (PMID:27219069) 
     
  
  
    
    González-Jiminéz, Mario ORCID: https://orcid.org/0000-0002-8853-0588, Ramakrishnan, Gopakumar, Harwood, Thomas, Lapthorn, Adrian J. 
ORCID: https://orcid.org/0000-0002-2197-8134, Kelly, Sharon M. 
ORCID: https://orcid.org/0000-0002-3516-1387, Ellis, Elizabeth M. and Wynne, Klaas 
ORCID: https://orcid.org/0000-0002-5305-5940
  
(2016)
  
Observation of coherent delocalized phonon-like modes in DNA under physiological conditions.
    
    Nature Communications, 7,
	 
      11799.
    
    (doi: 10.1038/ncomms11799)
    (PMID:27248361) 
    (PMCID:PMC4895446) 
  
  
    
    Ashraf, Khuram U., Josts, Inokentijs, Mosbahi, Khedidja, Kelly, Sharon M. ORCID: https://orcid.org/0000-0002-3516-1387, Byron, Olwyn 
ORCID: https://orcid.org/0000-0001-7857-4520, Smith, Brian O. 
ORCID: https://orcid.org/0000-0003-3363-4168 and Walker, Daniel 
ORCID: https://orcid.org/0000-0002-4206-2942
  
(2016)
  
The potassium binding protein Kbp is a cytoplasmic potassium sensor.
    
    Structure, 24(5),
	  pp. 741-749.
     
    
    (doi: 10.1016/j.str.2016.03.017)
    (PMID:27112601) 
     
  
  
2015
Huang, S. et al. (2015) Discovery of a single monooxygenase that catalyzes carbamate formation and ring contraction in the biosynthesis of the legonmycins. Angewandte Chemie (International Edition), 54(43), pp. 12697-12701. (doi: 10.1002/anie.201502902) (PMID:26206556)
    
    Pappas, Charalampos G., Mutasa, Tapiwa, Frederix, Pim W.J.M., Fleming, Scott, Bai, Shuo, Debnath, Sisir, Kelly, Sharon ORCID: https://orcid.org/0000-0002-3516-1387, Gachagan, Anthony and Ulijn, Rein V.
  
(2015)
  
Transient supramolecular reconfiguration of peptide nanostructures using ultrasound.
    
    Materials Horizons, 2(2),
	  pp. 198-202.
     
    
    (doi: 10.1039/c4mh00223g)
     
     
  
  
    
    Duffy, Margaret, Ma, Jiangtao, Deng, Lin, Dakin, Rachel S., Uil, Taco, Custers, Jerome, Kelly, Sharon M. ORCID: https://orcid.org/0000-0002-3516-1387, McVey, John H., Nicklin, Stuart A. 
ORCID: https://orcid.org/0000-0002-9691-6210 and Baker, Andrew H.
  
(2015)
  
Manipulating adenovirus hexon hypervariable loops dictates immune neutralisation and coagulation factor X-dependent cell interaction in vitro and in vivo.
    
    PLoS Pathogens, 11(2),
	 
      e1004673.
    
    (doi: 10.1371/journal.ppat.1004673)
    (PMID:25658827) 
    (PMCID:PMC4450073) 
  
  
    
    Löhner, Alexander, Carey, Anne-Marie, Hacking, Kirsty, Picken, Nichola, Kelly, Sharon ORCID: https://orcid.org/0000-0002-3516-1387, Cogdell, Richard 
ORCID: https://orcid.org/0000-0003-2119-6607 and Köhler, Jürgen
  
(2015)
  
The origin of the split B800 absorption peak in the LH2 complexes from Allochromatium vinosum.
    
    Photosynthesis Research, 123(1),
	  pp. 23-31.
     
    
    (doi: 10.1007/s11120-014-0036-2)
     
     
  
  
2014
    
    Carey, Anne-Marie, Hacking, Kirsty, Picken, Nichola, Honkanen, Suvi, Kelly, Sharon ORCID: https://orcid.org/0000-0002-3516-1387, Niedzwiedzki, Dariusz M., Blankenship, Robert E., Shimizu, Yuuki, Wang-Otomo, Zheng-Yu and Cogdell, Richard J. 
ORCID: https://orcid.org/0000-0003-2119-6607
  
(2014)
  
Characterisation of the LH2 spectral variants produced by the photosynthetic purple sulphur bacterium Allochromatium vinosum.
    
    Biochimica et Biophysica Acta: Bioenergetics, 1837(11),
	  pp. 1849-1860.
     
    
    (doi: 10.1016/j.bbabio.2014.07.022)
     
     
  
  
    
    Paul, Stephanie, Alegre, Kamela O., Holdsworth, Scarlett R., Rice, Matthew, Brown, James A., McVeigh, Paul, Kelly, Sharon M. ORCID: https://orcid.org/0000-0002-3516-1387 and Law, Christopher J.
  
(2014)
  
A single-component multidrug transporter of the major facilitator superfamily is part of a network that protects Escherichia coli from bile salt stress.
    
    Molecular Microbiology, 92(4),
	  pp. 872-884.
     
    
    (doi: 10.1111/mmi.12597)
     
     
  
  
McCaughey, L. C. et al. (2014) Lectin-like bacteriocins from Pseudomonas spp. utilise D-rhamnose containing lipopolysaccharide as a cellular receptor. PLoS Pathogens, 10(2), e1003898. (doi: 10.1371/journal.ppat.1003898) (PMID:24516380) (PMCID:PMC3916391)
    
    Josts, Inokentijs, Grinter, Rhys, Kelly, Sharon M. ORCID: https://orcid.org/0000-0002-3516-1387, Mosbahi, Khedidja, Roszak, Aleksander, Cogdell, Richard 
ORCID: https://orcid.org/0000-0003-2119-6607, Smith, Brian O. 
ORCID: https://orcid.org/0000-0003-3363-4168, Byron, Olwyn 
ORCID: https://orcid.org/0000-0001-7857-4520 and Walker, Daniel 
ORCID: https://orcid.org/0000-0002-4206-2942
  
(2014)
  
Recombinant expression, purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal DUF490963–1138 domain of TamB from Escherichia coli.
    
    Acta Crystallographica. Section F: Structural Biology Communications, 70(9),
	  pp. 1272-1275.
     
    
    (doi: 10.1107/S2053230X14017403)
     
     
  
  
Ritorto, M. S. et al. (2014) Screening of DUB activity and specificity by MALDI-TOF mass spectrometry. Nature Communications, 5, (doi: 10.1038/ncomms5763)
2013
    
    Duffy, Margaret R., Parker, Alan L., Kalkman, Eric R., White, Katie, Kovalskyy, Dmytro, Kelly, Sharon M. ORCID: https://orcid.org/0000-0002-3516-1387 and Baker, Andrew H.
  
(2013)
  
Identification of novel small molecule inhibitors of adenovirus gene transfer using a high throughput screening approach.
    
    Journal of Controlled Release, 170(1),
	  pp. 132-140.
     
    
    (doi: 10.1016/j.jconrel.2013.05.007)
     
     
  
  
    
    Fleming, J.R., Morgan, R.E., Fyfe, P.K., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387 and Hunter, W.
  
(2013)
  
The architecture of trypanosoma brucei tubulin-binding cofactor B and implications for function.
    
    FEBS Journal, 280(14),
	  pp. 3270-3280.
     
    
    (doi: 10.1111/febs.12308)
     
     
  
  
2012
    
    Edkins, A.L., Borland, G., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Cogdell, R.J. 
ORCID: https://orcid.org/0000-0003-2119-6607, Ozanne, B.W. and Cushley, W.
  
(2012)
  
Analysis of the CD23-αv integrin interaction: a study with model peptides.
    
    Biochemical and Biophysical Research Communications, 422(2),
	  pp. 207-212.
     
    
    (doi: 10.1016/j.bbrc.2012.04.076)
     
     
  
  
Christie, J.M. et al. (2012) Plant UVR8 photoreceptor senses UV-B by tryptophan-mediated disruption of cross-dimer salt bridges. Science, 335(6075), pp. 1492-1496. (doi: 10.1126/science.1218091)
    
    Abdulrahman, N.A., Fan, Z., Tonooka, T., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Gadegaard, N. 
ORCID: https://orcid.org/0000-0002-3396-846X, Hendry, E., Govorov, A.O. and Kadodwala, M. 
ORCID: https://orcid.org/0000-0003-4989-5688
  
(2012)
  
Induced chirality through electromagnetic coupling between chiral molecular layers and plasmonic nanostructures.
    
    Nano Letters, 12(2),
	  pp. 977-983.
     
    
    (doi: 10.1021/nl204055r)
    (PMID:22263754) 
     
  
  
    
    Brand, G.D., Magalhães, M.T.Q., Tinoco, M.L.P., Aragão, F.J.L., Nicoli, J., Kelly, S. ORCID: https://orcid.org/0000-0002-3516-1387, Cooper, A. and Bloch Jr, C.
  
(2012)
  
Probing protein sequences as sources for encrypted antimicrobial peptides.
    
    PLoS ONE, 7(9),
	  e45848.
     
    
    (doi: 10.1371/journal.pone.0045848)
    (PMID:23029273) 
    (PMCID:PMC3461044) 
  
  
2011
    
    McEwan, A.R., Raab, A., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Feldmann, J. and Smith, M.C.M.
  
(2011)
  
Zinc is essential for high-affinity DNA binding and recombinase activity of φC31 integrase.
    
    Nucleic Acids Research, 39(14),
	  pp. 6137-6147.
     
    
    (doi: 10.1093/nar/gkr220)
     
     
  
  
    
    Coates, C.J., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387 and Nairn, J.
  
(2011)
  
Possible role of phosphatidylserine–hemocyanin interaction in the innate immune response of Limulus polyphemus.
    
    Developmental and Comparative Immunology, 35(2),
	  pp. 155-163.
     
    
    (doi: 10.1016/j.dci.2010.08.015)
     
     
  
  
2010
    
    Vijayakrishnan, S. ORCID: https://orcid.org/0000-0002-1895-1272, Kelly, S.M., Gilbert, R.J.C., Callow, P., Bhella, D. 
ORCID: https://orcid.org/0000-0003-2096-8310, Forsyth, T., Lindsay, J.G. and Byron, O.
  
(2010)
  
Solution structure and characterisation of the human pyruvate dehydrogenase complex core assembly.
    
    Journal of Molecular Biology, 399(1),
	  pp. 71-93.
     
    
    (doi: 10.1016/j.jmb.2010.03.043)
    (PMID:20361979) 
    (PMCID:PMC2880790) 
  
  
    
    Daniel, R.M., Peterson, M.E., Danson, M.J., Price, N.C., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Monk, C.R., Weinberg, C.S., Oudshoorn, M.L. and Lee, C.K.
  
(2010)
  
The molecular basis of the effect of temperature on enzyme activity.
    
    Biochemical Journal, 425(2),
	  pp. 353-360.
     
    
    (doi: 10.1042/BJ20091254)
     
     
  
  
    
    Fischer, K., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Watt, K., Price, N.C. and McEwan, I. J.
  
(2010)
  
Conformation of the Mineralocorticoid Receptor N-terminal Domain: Evidence for Induced and Stable Structure.
    
    Molecular Endocrinology, 24(10),
	  pp. 1935-1948.
     
    
    (doi: 10.1210/me.2010-0005)
     
     
  
  
    
    Houssen, W.E., Wright, S.H., Kalverda, A.P., Thompson, G.S., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387 and Jaspars, M.
  
(2010)
  
Solution structure of the leader sequence of the patellamide precursor peptide, PatE1-34.
    
    ChemBioChem, 11(13),
	  pp. 1867-1873.
     
    
    (doi: 10.1002/cbic.201000305)
     
     
  
  
    
    Patwardhan, S.V., Holt, S.A., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Kreiner, M., Perry, C.C. and van der Walle, C.F.
  
(2010)
  
Silica Condensation by a Silicatein α Homologue Involves Surface-Induced Transition to a Stable Structural Intermediate Forming a Saturated Monolayer.
    
    Biomacromolecules, 11(11),
	  pp. 3126-3135.
     
    
    (doi: 10.1021/bm100932e)
     
     
  
  
    
    Patwardhan, S.V., Holt, S.A., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Kreiner, M., Perry, C.C. and van der Walle, C.F.
  
(2010)
  
Silica condensation by a silicatein α homologue involves surface-induced transition to a stable structural intermediate forming a saturated monolayer.
    
    Biomacromolecules, 11(11),
	  pp. 3126-3135.
     
    
    (doi: 10.1021/bm100932e)
     
     
  
  
2009
    
    Cheung, G.Y.C., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Jess, T.J., Prior, S., Price, N.C., Parton, R.G. and Coote, J.G.
  
(2009)
  
Functional and structural studies on different forms of the adenylate cyclase toxin of Bordetella pertussis.
    
    Microbial Pathogenesis, 46(1),
	  pp. 36-42.
     
    
    (doi: 10.1016/j.micpath.2008.10.005)
     
     
  
  
Aran-Ponte, V., Brandie, F.M., Boyd, A.R., Kantidakis, T., Rideout, E.J., Kelly, S.M., Gould, G.W. and Bryant, N.J. (2009) Characterization of two distinct binding modes between syntaxin 4 and Munc18c. Biochemical Journal, 419(Pt3), pp. 655-660. (doi: 10.1042/BJ20082293) (PMID:19193195)
Cardoso, T. et al. (2009) Acetonitrile-induced unfolding of porcine pepsin A: a proposal for a critical role of hydration structures in conformational stability. International Journal of Biological Macromolecules, 45(3), pp. 213-220. (doi: 10.1016/j.ijbiomac.2009.05.006)
    
    Ganesan, A., Moore, B.D., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Price, N.C., Rolinski, O.J., Birch, D.J.S., Dunkin, I.R. and Halling, P.J.
  
(2009)
  
Optical spectroscopic methods for probing the conformational stability of immobilised enzymes.
    
    ChemPhysChem, 10(9-10),
	  pp. 1492-1499.
     
    
    (doi: 10.1002/cphc.200800759)
     
     
  
  
    
    Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387 and Price, N.C.
  
(2009)
  
Circular Dichroism: Studies of Proteins.
    
    
      In: 
      Encyclopedia of Life Sciences.
    
    
    Wiley.
        
        (doi: 10.1002/9780470015902.a0003043.pub2)
  
  
    
    Lamb, D., Mirsaliotis, A., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387 and Brighty, D.W.
  
(2009)
  
Basic residues are critical to the activity of peptide inhibitors of human T cell leukemia virus type 1 entry.
    
    Journal of Biological Chemistry, 284(10),
	  pp. 6575-6584.
     
    
    (doi: 10.1074/jbc.M806725200)
     
     
  
  
2008
    
    Pereira, P., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Gellert, P.R. and van der Walle, C.F.
  
(2008)
  
Interdomain mobility and conformational stability of type III fibronectin domain pairs control surface adsorption, desorption and unfolding.
    
    Colloids and Surfaces B: Biointerfaces, 64(1),
	  pp. 1-9.
     
    
    (doi: 10.1016/j.colsurfb.2007.12.015)
     
     
  
  
    
    Davies, P., Watts, K., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Clark, C., Price, N.C. and McEwan, I.J.
  
(2008)
  
Consequences of poly-glutamine repeat length for the conformation and folding of the androgen receptor amino-terminal domain.
    
    Journal of Molecular Endocrinology, 41,
	  pp. 301-314.
     
    
    (doi: 10.1677/JME-08-0042)
     
     
  
  
    
    Kreiner, M., Li, Z., Beattie, J., Kelly, SM. ORCID: https://orcid.org/0000-0002-3516-1387, Mardon, HJ. and van der Walle, C.F.
  
(2008)
  
Self-assembling multimeric integrin {alpha}5{beta}1 ligands for cell attachment and spreading.
    
    Protein Engineering Design and Selection, 21(9),
	  pp. 553-560.
     
    
    (doi: 10.1093/protein/gzn032)
     
     
  
  
Zhu, F., Davies, P., Thompsett, A.R., Kelly, S.M., Tranter, G.E., Hecht, L., Isaacs, N.W., Brown, D.R. and Barron, L.D. (2008) Raman optical activity and circular dichroism reveal dramatic differences in the influence of divalent copper and manganese ions on prion protein folding. Biochemistry, 47(8), pp. 2510-2517. (doi: 10.1021/bi7022893)
2007
    
    Jones, Matthew A. ORCID: https://orcid.org/0000-0002-3943-3968, Feeney, Kevin A., Kelly, Sharon M. 
ORCID: https://orcid.org/0000-0002-3516-1387 and Christie, John M. 
ORCID: https://orcid.org/0000-0002-9976-0055
  
(2007)
  
Mutational analysis of phototropin 1 provides insights into the mechanism underlying LOV2 signal transmission.
    
    Journal of Biological Chemistry, 282(9),
	  pp. 6405-6414.
     
    
    (doi: 10.1074/jbc.M605969200)
    (PMID:17164248) 
     
  
  
2003
Alexeev, D. et al. (2003) Synthesis, structural and biological studies of ubiquitin mutants containing (2S, 4S)-5-fluoroleucine residues strategically placed in the hydrophobic core. ChemBioChem, 4(9), pp. 894-896. (doi: 10.1002/cbic.200300699)
    
    Cerasoli, E., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Coggins, J.R., Lapthorn, A.J. 
ORCID: https://orcid.org/0000-0002-2197-8134, Clarke, D.T. and Price, N.C.
  
(2003)
  
Effects of salts on the function and conformational stability of shikimate kinase.
    
    Biochimica et Biophysica Acta: Proteins and Proteomics, 1648(1-2),
	  pp. 43-54.
     
    
    (doi: 10.1016/S1570-9639(03)00110-9)
     
     
  
  
    
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    Pereira, P., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Gellert, P.R. and van der Walle, C.F.
  
(2008)
  
Interdomain mobility and conformational stability of type III fibronectin domain pairs control surface adsorption, desorption and unfolding.
    
    Colloids and Surfaces B: Biointerfaces, 64(1),
	  pp. 1-9.
     
    
    (doi: 10.1016/j.colsurfb.2007.12.015)
     
     
  
  
    
    Davies, P., Watts, K., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Clark, C., Price, N.C. and McEwan, I.J.
  
(2008)
  
Consequences of poly-glutamine repeat length for the conformation and folding of the androgen receptor amino-terminal domain.
    
    Journal of Molecular Endocrinology, 41,
	  pp. 301-314.
     
    
    (doi: 10.1677/JME-08-0042)
     
     
  
  
    
    Kreiner, M., Li, Z., Beattie, J., Kelly, SM. ORCID: https://orcid.org/0000-0002-3516-1387, Mardon, HJ. and van der Walle, C.F.
  
(2008)
  
Self-assembling multimeric integrin {alpha}5{beta}1 ligands for cell attachment and spreading.
    
    Protein Engineering Design and Selection, 21(9),
	  pp. 553-560.
     
    
    (doi: 10.1093/protein/gzn032)
     
     
  
  
Zhu, F., Davies, P., Thompsett, A.R., Kelly, S.M., Tranter, G.E., Hecht, L., Isaacs, N.W., Brown, D.R. and Barron, L.D. (2008) Raman optical activity and circular dichroism reveal dramatic differences in the influence of divalent copper and manganese ions on prion protein folding. Biochemistry, 47(8), pp. 2510-2517. (doi: 10.1021/bi7022893)
    
    Jones, Matthew A. ORCID: https://orcid.org/0000-0002-3943-3968, Feeney, Kevin A., Kelly, Sharon M. 
ORCID: https://orcid.org/0000-0002-3516-1387 and Christie, John M. 
ORCID: https://orcid.org/0000-0002-9976-0055
  
(2007)
  
Mutational analysis of phototropin 1 provides insights into the mechanism underlying LOV2 signal transmission.
    
    Journal of Biological Chemistry, 282(9),
	  pp. 6405-6414.
     
    
    (doi: 10.1074/jbc.M605969200)
    (PMID:17164248) 
     
  
  
Alexeev, D. et al. (2003) Synthesis, structural and biological studies of ubiquitin mutants containing (2S, 4S)-5-fluoroleucine residues strategically placed in the hydrophobic core. ChemBioChem, 4(9), pp. 894-896. (doi: 10.1002/cbic.200300699)
    
    Cerasoli, E., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Coggins, J.R., Lapthorn, A.J. 
ORCID: https://orcid.org/0000-0002-2197-8134, Clarke, D.T. and Price, N.C.
  
(2003)
  
Effects of salts on the function and conformational stability of shikimate kinase.
    
    Biochimica et Biophysica Acta: Proteins and Proteomics, 1648(1-2),
	  pp. 43-54.
     
    
    (doi: 10.1016/S1570-9639(03)00110-9)
     
     
  
  
    
    Garofalo, A., Rowlinson, M.C., Amambua, N.A., Hughes, J.M., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Price, N.C., Cooper, A., Watson, D.G., Kennedy, M.W. 
ORCID: https://orcid.org/0000-0002-0970-5264 and Bradley, J.E.
  
(2003)
  
The FAR protein family of the nematode Caenorhabditis elegans - Differential lipid binding properties, structural characteristics, and developmental regulation.
    
    Journal of Biological Chemistry, 278,
	  pp. 8065-8074.
     
    
    (doi: 10.1074/jbc.M206278200)
     
     
  
  
    
    Ackerman, Claire J., Harnett, Margaret M. ORCID: https://orcid.org/0000-0001-5740-3028, Harnett, William, Kelly, Sharon M. 
ORCID: https://orcid.org/0000-0002-3516-1387, Svergun, Dmitri I. and Byron, Olwyn 
ORCID: https://orcid.org/0000-0001-7857-4520
  
(2003)
  
19 angstrom solution structure of the filarial nematode immunomodulatory protein, ES-62.
    
    Biophysical Journal, 84(1),
	  pp. 489-500.
     
    
    (doi: 10.1016/S0006-3495(03)74868-1)
    (PMID:12524301) 
    (PMCID:PMC1302629) 
  
  
    
    McCLelland, D.A., Aitken, J.D., Bhella, David ORCID: https://orcid.org/0000-0003-2096-8310, McNab, David, Mitchell, Joyce, Kelly, S.M. 
ORCID: https://orcid.org/0000-0002-3516-1387, Price, N.C. and Rixon, F.J.
  
(2002)
  
pH reduction as a trigger for dissociation of herpes simplex virus type 1 scaffolds.
    
    Journal of Virology, 76,
	  pp. 7407-7417.
     
    
    (doi: 10.1128/VJI.76.15.7407-7417.2002)
     
     
  
  
    
    McDermott, L., Moore, J., Brass, A., Price, N.C., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Cooper, A. and Kennedy, MW. 
ORCID: https://orcid.org/0000-0002-0970-5264
  
(2001)
  
Mutagenic and chemical modification of the ABA-1 allergen of the nematode Ascaris: Consequences for structure and lipid binding properties.
    
    Biochemistry, 40(33),
	  pp. 9918-9926.
     
    
    (doi: 10.1021/bi0026876)
     
     
  
  
    
    Kirkitadze, M.D., Barlow, P.N., Price, N.C., Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387, Boutell, C.J. 
ORCID: https://orcid.org/0000-0002-2970-7785, Rixon, F.J. and McClelland, D.A.
  
(1998)
  
The herpes simplex virus triplex protein, VP23, exists as a molten globule.
    
    Journal of Virology, 72(12),
	  pp. 10066-10072.
     
    
    
     
     
  
  
    
    Kennedy, Malcolm W. ORCID: https://orcid.org/0000-0002-0970-5264, Britton, Collette 
ORCID: https://orcid.org/0000-0002-5165-312X, Price, Nicholas C., Kelly, Sharon M. 
ORCID: https://orcid.org/0000-0002-3516-1387 and Cooper, Alan
  
(1995)
  
The DvA-1 polyprotein of the parasitic nematode Dictyocaulus viviparus. A small helix-rich lipid-binding protein.
    
    Journal of Biological Chemistry, 270(33),
	  pp. 19277-19281.
     
    
    (doi: 10.1074/jbc.270.33.19277)
    (PMID:7642601) 
     
  
  
Book Sections
    
    Kelly, S.M. ORCID: https://orcid.org/0000-0002-3516-1387 and Price, N.C.
  
(2009)
  
Circular Dichroism: Studies of Proteins.
    
    
      In: 
      Encyclopedia of Life Sciences.
    
    
    Wiley.
        
        (doi: 10.1002/9780470015902.a0003043.pub2)
  
  
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Solvation dynamics and structure around proteins and peptides: collective network motions vs. weak interactions
 Engineering and Physical Sciences Research Council
 2014 - 2017
 
- Ultrasensitive characterisation of biological structure with supertwisted light
 Leverhulme Trust
 2013 - 2016
 
- Bridging the GAP-EPSRC: Development of biosensing applications of superchiral fields
 Engineering and Physical Sciences Research Council
 2011 - 2012
 
- KTA-EPSRC: Superchiral light: The basis of a generic biosensing platform
 Engineering and Physical Sciences Research Council
 2009 - 2012
 
- Enhancement of Circular Dichroism facility
 Biotechnology and Biological Sciences Research Council
 2003 - 2006
 
Research datasets
2016
Gonzalez-Jimenez, M., Ramakrishnan, G., Harwood, T., Lapthorn, A. , Kelly, S. , Ellis, E. and Wynne, K. (2016) Observation of coherent delocalised phonon-like modes in DNA under physiological conditions. [Data Collection]
Additional information
Editorial Board
- 2004 - present: Current Protein and Peptide Science
Grant Advisory Board
- 2005 - present: Protein Circular Dichroism Data Bank - International Advisory Panel
- 2004 - present: Centre for Membrane Protein Structure and Dynamics, Daresbury - Associates Advisory Group
- - present: Protein Circular Dichroism Databank - International Scientific Advisory Board, with F. Formaggio (Padua, Italy), K. Gekko (HiSoR, Japan), N. Greenfield (NJMDS, USA), J-C. Maurizot (Orleans, France), A. Rodger (Warwick, UK), J. Sutherland (BNL,USA)
- - present: European Circular Dichroism Workshop, in collaboration with Prof. Alison Rodger of the University of Warwick
- - present: Anka Synchrotron, Karlsruhe, Germany - Member of CD project assessment panel, Centre for Protein and Membrane Structure and Dynamics
Invited International Presentations
- 2003: European Circular Dichroism Workshop - Annual Presentations
- 2003: UK - Circular Dichroism Users Group
Professional Learned Society
- 2002 - present: British Mass Spectrometry Society - Ordinary Member
- 2002 - present: Association of Biomolecular Resource Facilities - Ordinary Member
- 2002 - present: International Mass Spectrometry Society - Ordinary Member
- 1992 - present: Biochemical Society - Ordinary Member
