Miss Bethany Fleming

  • Technician (Molecular Biosciences)

Biography

Key Skills 

Grant Funded

I have 4 years of cell culture experience, producing primary and working cell banks for clients and maintenance of company stocks. I have worked with mammalian, insect, bird and stem cell lines, using a range of growth techniques. With regards to molecular lab techniques; PCR, gel electrophoresis, CRISPR/Cas9 system, protein expression, western blotting, cloning. 

The majority of my career so far has been spent in industry, working in a GMP lab environment for 3.5 years. This means adhering to all laws and regulations surrounding this, and therefore I am familiar with documentation, archiving, record keeping and so on to the standard of GMP requirements. My time in industry has allowed me the opportunity to work directly with clients as well as auditors from regulatory bodies such as FDA, MHRA etc. 

 

Research interests

I'm new to research, having graduated from University of Glasgow studying Virology in 2015 and gone straight into industry. Virology, along with other infection biology subjects, still remains of great interest to me. 

In my current role my group's focus is primarily looking at how proteins are made and delivered outside the cell and, in particular, how this delivery process breaks down during disease. With a particular focus on how cells fold and assemble proteins correctly. 

Publications

List by: Type | Date

Jump to: 2023 | 2022 | 2021
Number of items: 3.

2023

Robinson, Philip John ORCID logoORCID: https://orcid.org/0000-0003-2576-5010, Pringle, Marie Anne ORCID logoORCID: https://orcid.org/0000-0002-1358-4610, Fleming, Bethany and Bulleid, Neil John ORCID logoORCID: https://orcid.org/0000-0002-9839-5279 (2023) Distinct role of ERp57 and ERdj5 as a disulfide isomerase and reductase during ER protein folding. Journal of Cell Science, 136(2), jcs260656. (doi: 10.1242/jcs.260656) (PMID:36655611) (PMCID:PMC10022741)

2022

Oka, Ojore Benedict Valentine ORCID logoORCID: https://orcid.org/0000-0003-3482-115X, Pierre, Arvin Shedrach, Pringle, Marie Anne ORCID logoORCID: https://orcid.org/0000-0002-1358-4610, Tungkum, Wanida, Cao, Zhenbo, Fleming, Bethany and Bulleid, Neil John ORCID logoORCID: https://orcid.org/0000-0002-9839-5279 (2022) Activation of the UPR sensor ATF6α is regulated by its redox-dependent dimerization and ER retention by ERp18. Proceedings of the National Academy of Sciences of the United States of America, 119(12), e2122657119. (doi: 10.1073/pnas.2122657119) (PMID:35286189) (PMCID:PMC8944254)

2021

van Lith, Marcel, Pringle, Marie Anne ORCID logoORCID: https://orcid.org/0000-0002-1358-4610, Fleming, Bethany, Gaeta, Giorgia, Im, Jisu, Gilmore, Reid and Bulleid, Neil J. ORCID logoORCID: https://orcid.org/0000-0002-9839-5279 (2021) A cytosolic reductase pathway is required for efficient N-glycosylation of an STT3B-dependent acceptor site. Journal of Cell Science, 134(22), jcs259340. (doi: 10.1242/jcs.259340) (PMID:34734627) (PMCID:PMC8645230)

This list was generated on Mon Jun 16 02:18:35 2025 BST.
Jump to: Articles
Number of items: 3.

Articles

Robinson, Philip John ORCID logoORCID: https://orcid.org/0000-0003-2576-5010, Pringle, Marie Anne ORCID logoORCID: https://orcid.org/0000-0002-1358-4610, Fleming, Bethany and Bulleid, Neil John ORCID logoORCID: https://orcid.org/0000-0002-9839-5279 (2023) Distinct role of ERp57 and ERdj5 as a disulfide isomerase and reductase during ER protein folding. Journal of Cell Science, 136(2), jcs260656. (doi: 10.1242/jcs.260656) (PMID:36655611) (PMCID:PMC10022741)

Oka, Ojore Benedict Valentine ORCID logoORCID: https://orcid.org/0000-0003-3482-115X, Pierre, Arvin Shedrach, Pringle, Marie Anne ORCID logoORCID: https://orcid.org/0000-0002-1358-4610, Tungkum, Wanida, Cao, Zhenbo, Fleming, Bethany and Bulleid, Neil John ORCID logoORCID: https://orcid.org/0000-0002-9839-5279 (2022) Activation of the UPR sensor ATF6α is regulated by its redox-dependent dimerization and ER retention by ERp18. Proceedings of the National Academy of Sciences of the United States of America, 119(12), e2122657119. (doi: 10.1073/pnas.2122657119) (PMID:35286189) (PMCID:PMC8944254)

van Lith, Marcel, Pringle, Marie Anne ORCID logoORCID: https://orcid.org/0000-0002-1358-4610, Fleming, Bethany, Gaeta, Giorgia, Im, Jisu, Gilmore, Reid and Bulleid, Neil J. ORCID logoORCID: https://orcid.org/0000-0002-9839-5279 (2021) A cytosolic reductase pathway is required for efficient N-glycosylation of an STT3B-dependent acceptor site. Journal of Cell Science, 134(22), jcs259340. (doi: 10.1242/jcs.259340) (PMID:34734627) (PMCID:PMC8645230)

This list was generated on Mon Jun 16 02:18:35 2025 BST.