Ms Afroditi Chatzi
- Research Associate (Molecular Biosciences)
telephone:
0141 330 6220
email:
Afroditi.Chatzi@glasgow.ac.uk
lab 412, Molecular Cell & Systems Biology, Davidson Building
Publications
2021
Ciosi, M. et al. (2021) Approaches to sequence the HTT CAG repeat expansion and quantify repeat length variation. Journal of Huntington's Disease, 10(1), pp. 53-74. (doi: 10.3233/jhd-200433) (PMID:33579864) (PMCID:PMC7990409)
2020
Lu, A. T. et al. (2020) DNA methylation study of Huntington's disease and motor progression in patients and in animal models. Nature Communications, 11, 4529. (doi: 10.1038/s41467-020-18255-5) (PMID:32913184) (PMCID:PMC7484780)
Ellis, N. et al. (2020) Genetic risk underlying psychiatric and cognitive symptoms in Huntington’s Disease. Biological Psychiatry, 87(9), pp. 857-865. (doi: 10.1016/j.biopsych.2019.12.010) (PMID:32087949)
2019
Lee, J.-M. et al. (2019) CAG repeat not polyglutamine length determines timing of Huntington’s disease onset. Cell, 178(4), 887-900.e14. (doi: 10.1016/j.cell.2019.06.036)
2018
Ging, H., Nethisinghe, S., Chatzi, A., Ciosi, M. , Monckton, D. G. and Giunti, P. (2018) Determining the CAG Repeat Mosaic in Post-mortem Human HD Brains. EHDN 2018 Plenary Meeting, Vienna, Austria, 14-16 Sep 2018.
Cardenas-Rodriguez, M., Chatzi, A. and Tokatlidis, K. (2018) Iron–sulfur clusters: from metals through mitochondria biogenesis to disease. Journal of Biological Inorganic Chemistry, 23(4), pp. 509-520. (doi: 10.1007/s00775-018-1548-6) (PMID:29511832) (PMCID:PMC6006200)
Egea, J. et al. (2018) Corrigendum to “European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” [Redox Biol. 13 (2017) 94–162]. Redox Biology, 14, pp. 694-696. (doi: 10.1016/j.redox.2017.10.001) (PMID:29107648)
2017
Egea, J. et al. (2017) European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). Redox Biology, 13, pp. 94-162. (doi: 10.1016/j.redox.2017.05.007) (PMID:28577489)
Kritsiligkou, P., Chatzi, A., Charalampous, G., Mironov, A., Grant, C. M. and Tokatlidis, K. (2017) Unconventional targeting of a thiol peroxidase to the mitochondrial intermembrane space facilitates oxidative protein folding. Cell Reports, 18(11), pp. 2729-2741. (doi: 10.1016/j.celrep.2017.02.053) (PMID:28297675) (PMCID:PMC5368413)
2016
Chatzi, A., Manganas, P. and Tokatlidis, K. (2016) Oxidative folding in the mitochondrial intermembrane space: a regulated process important for cell physiology and disease. Biochimica et Biophysica Acta: Molecular Cell Research, 1863(6 Pt.A), pp. 1298-1306. (doi: 10.1016/j.bbamcr.2016.03.023) (PMID:27033519)
2015
Hangen, E. et al. (2015) Interaction between AIF and CHCHD4 regulates respiratory chain biogenesis. Molecular Cell, 58(6), pp. 1001-1014. (doi: 10.1016/j.molcel.2015.04.020) (PMID:26004228)
2013
Chatzi, A., Sideris, D.P., Katrakili, N., Pozidis, C. and Tokatlidis, K. (2013) Biogenesis of yeast Mia40 - uncoupling folding from import and atypical recognition features. FEBS Journal, 280(20), pp. 4960-4969. (doi: 10.1111/febs.12482)
Chatzi, A. and Tokatlidis, K. (2013) The mitochondrial intermembrane space: a hub for oxidative folding linked to protein biogenesis. Antioxidants and Redox Signaling, 19(1), pp. 54-62. (doi: 10.1089/ars.2012.4855) (PMID:22901034)
2011
Banci, L., Bertini, I., Ciofi-Baffoni, S., Boscaro, F., Chatzi, A., Mikolajczyk, M., Tokatlidis, K. and Winkelmann, J. (2011) Anamorsin is a [2Fe-2S] cluster-containing substrate of the Mia40-dependent mitochondrial protein trapping machinery. Chemistry and Biology, 18(6), pp. 794-804. (doi: 10.1016/j.chembiol.2011.03.015) (PMID:21700214)
Articles
Ciosi, M. et al. (2021) Approaches to sequence the HTT CAG repeat expansion and quantify repeat length variation. Journal of Huntington's Disease, 10(1), pp. 53-74. (doi: 10.3233/jhd-200433) (PMID:33579864) (PMCID:PMC7990409)
Lu, A. T. et al. (2020) DNA methylation study of Huntington's disease and motor progression in patients and in animal models. Nature Communications, 11, 4529. (doi: 10.1038/s41467-020-18255-5) (PMID:32913184) (PMCID:PMC7484780)
Ellis, N. et al. (2020) Genetic risk underlying psychiatric and cognitive symptoms in Huntington’s Disease. Biological Psychiatry, 87(9), pp. 857-865. (doi: 10.1016/j.biopsych.2019.12.010) (PMID:32087949)
Lee, J.-M. et al. (2019) CAG repeat not polyglutamine length determines timing of Huntington’s disease onset. Cell, 178(4), 887-900.e14. (doi: 10.1016/j.cell.2019.06.036)
Cardenas-Rodriguez, M., Chatzi, A. and Tokatlidis, K. (2018) Iron–sulfur clusters: from metals through mitochondria biogenesis to disease. Journal of Biological Inorganic Chemistry, 23(4), pp. 509-520. (doi: 10.1007/s00775-018-1548-6) (PMID:29511832) (PMCID:PMC6006200)
Egea, J. et al. (2018) Corrigendum to “European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” [Redox Biol. 13 (2017) 94–162]. Redox Biology, 14, pp. 694-696. (doi: 10.1016/j.redox.2017.10.001) (PMID:29107648)
Egea, J. et al. (2017) European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). Redox Biology, 13, pp. 94-162. (doi: 10.1016/j.redox.2017.05.007) (PMID:28577489)
Kritsiligkou, P., Chatzi, A., Charalampous, G., Mironov, A., Grant, C. M. and Tokatlidis, K. (2017) Unconventional targeting of a thiol peroxidase to the mitochondrial intermembrane space facilitates oxidative protein folding. Cell Reports, 18(11), pp. 2729-2741. (doi: 10.1016/j.celrep.2017.02.053) (PMID:28297675) (PMCID:PMC5368413)
Chatzi, A., Manganas, P. and Tokatlidis, K. (2016) Oxidative folding in the mitochondrial intermembrane space: a regulated process important for cell physiology and disease. Biochimica et Biophysica Acta: Molecular Cell Research, 1863(6 Pt.A), pp. 1298-1306. (doi: 10.1016/j.bbamcr.2016.03.023) (PMID:27033519)
Hangen, E. et al. (2015) Interaction between AIF and CHCHD4 regulates respiratory chain biogenesis. Molecular Cell, 58(6), pp. 1001-1014. (doi: 10.1016/j.molcel.2015.04.020) (PMID:26004228)
Chatzi, A., Sideris, D.P., Katrakili, N., Pozidis, C. and Tokatlidis, K. (2013) Biogenesis of yeast Mia40 - uncoupling folding from import and atypical recognition features. FEBS Journal, 280(20), pp. 4960-4969. (doi: 10.1111/febs.12482)
Chatzi, A. and Tokatlidis, K. (2013) The mitochondrial intermembrane space: a hub for oxidative folding linked to protein biogenesis. Antioxidants and Redox Signaling, 19(1), pp. 54-62. (doi: 10.1089/ars.2012.4855) (PMID:22901034)
Banci, L., Bertini, I., Ciofi-Baffoni, S., Boscaro, F., Chatzi, A., Mikolajczyk, M., Tokatlidis, K. and Winkelmann, J. (2011) Anamorsin is a [2Fe-2S] cluster-containing substrate of the Mia40-dependent mitochondrial protein trapping machinery. Chemistry and Biology, 18(6), pp. 794-804. (doi: 10.1016/j.chembiol.2011.03.015) (PMID:21700214)
Conference or Workshop Item
Ging, H., Nethisinghe, S., Chatzi, A., Ciosi, M. , Monckton, D. G. and Giunti, P. (2018) Determining the CAG Repeat Mosaic in Post-mortem Human HD Brains. EHDN 2018 Plenary Meeting, Vienna, Austria, 14-16 Sep 2018.
