Professor Shauna Culshaw

  • Professor of Periodontology and Immunology (Dental School)

email: Shauna.Culshaw@glasgow.ac.uk

School of Medicine, Dentistry & Nursing, L14 Level 9, 378 Sauchiehall Street, Glasgow Dental Hospital & School, Glasgow, G2 3JZ

Import to contacts

ORCID iDhttps://orcid.org/0000-0002-9653-5629

Biography

Shauna is an Honorary Consultant in Periodontics, Senior Clinical Lecturer, Clinical Research Facility Lead and Lead for Undergraduate teaching in Periodontics.  During undergraduate dental training in Glasgow, she completed an intercalated degree in immunology. These studies extended to an intercalated PhD examining the role of cytokines in inflammation. In 2011, she completed specialist training in Periodontics and the following year, commenced an Honorary Consultant Post in Periodontics, at the same time becoming the first dentist to be awarded the Scottish Funding Council’s Senior Clinical Research Fellowship. Currently, Shauna treats patients referred for specialist periodontal care; leads a research group focused on the local and systemic consequences of the immune response in the oral cavity; and trains undergraduate and postgraduate students, NHS hospital and University staff.

Research interests

Also investigating local and systemic consequences of the immune response in the oral cavity: 

Jason Brown

PhD Student, University of West of Scotland
Investigating innate lymphoid cells in the oral cavity.

"Jason graduated from Durham University in 2014 with a BSc in Biomedical Science, before completing a MPhil at the Liverpool University Dental School the following academic year. In 2015 Jason started his PhD jointly at University of the West of Scotland and Glasgow University investigating the immune response in periodontitis"

Robert Reilly

Clinical Research Fellow, PhD Student
Leukocyte trafficking in the oral mucosa

"As a Dentist I am interested in identifying how the immune system works in the mouth.  My research aims to identify the mechanisms that causes T-Cells to move to the mouth in health and disease.  By understanding these mechanisms it may identify new treatments for a range of oral diseases."

Laura Cameron

PhD Student, Industrial PhD Partnership with Dentsply Sirona
Investigating the immune response after periodontal treatment

Michael Paterson

Specialist Registrar in Restorative Dentistry, undertaking a research MSc investigating how treatment for gum disease affects the body as a whole.  

Recent Group Members:

Jennifer Malcolm 

Post-Doctorate Research assistant funded by Arthritis Research UK
Investigating the immune response to citrullinated antigen

"Jennifer graduated from Glasgow Caledonian University with a B.Sc (Hons) in Microbiology in 2008. Jennifer then moved to the Glasgow Dental School to undertake her PhD to investigating the relationship between salivary immune responses and the oral biofilm development in young children, which was awarded in 2013. Jennifer currently works at the Institute for Infection, Immunity and Inflammation, investigating how post translational antigen modification alters the immune response."

Ana Adrados

Ana Adrados Planell graduated from Universitat Politècnica de València with a M.Eng. in Agricultural Engineering with intensification in Biotechnology and Breeding in 2010, and an M.Sc. in Biotechology in 2014. In 2011 Ana took up a position as a research assistant at the Institute of Molecular Recognition and Technological Development (IDM) to work with microarray technology of nucleic acids. In 2012, Ana moved to Glasgow to take up the Marie-Curie ITN-RAPID PhD studentship investigating the role of citrullination in the host response to periodontal infection and its relation to autoimmunity, in particular rheumatoid arthritis.

http://www.birmingham.ac.uk/rapid

Lauren Campbell

Lauren graduated from the University of Strathclyde in June 2013 with First Class Honours in Biomedical Science. In September 2013, Lauren started the Sir Jules Thorn PhD studentship, at the Institute for Infection Immunity and Inflammation, investigating the T cells found in gingiva in health and disease.

Collaborators

John Butcher  - University of the West of Scotland
http://www.uws.ac.uk/staff-profiles/science/john-butcher/ 

Alex Mira - Centro Superior de Investigación en Salud Pública - Valencia
http://centros.csisp.gva.es/web/oral-microbiome-laboratory/people

Publications

List by: Type | Date

Jump to: 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2008 | 2007 | 2005 | 2004 | 2003 | 2001
Number of items: 55.

2024

Lopez‐Oliva, I., Malcolm, J. and Culshaw, S. (2024) Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases. Periodontology 2000, (doi: 10.1111/prd.12530) (Early Online Publication)

Rosier, B. T. et al. (2024) Publisher Correction: Nitrate reduction capacity of the oral microbiota is impaired in periodontitis: potential implications for systemic nitric oxide availability. International Journal of Oral Science, 16, 8. (doi: 10.1038/s41368-024-00283-2) (PMID:38272860) (PMCID:PMC10811215)

2023

Aminu, A. Q. et al. (2023) Inequalities in access to NHS primary care dental services in Scotland during the COVID-19 pandemic. British Dental Journal, (doi: 10.1038/s41415-023-5856-z) (PMID:37225842) (PMCID:PMC10208681) (Early Online Publication)

Johnston, W. et al. (2023) Longitudinal changes in subgingival biofilm composition following periodontal treatment. Journal of Periodontology, (doi: 10.1002/JPER.22-0749) (PMID:36960491) (Early Online Publication)

Malcolm, J. et al. (2023) C-terminal citrullinated peptide alters antigen-specific APC:T cell interactions leading to breach of immune tolerance. Journal of Autoimmunity, 135, 102994. (doi: 10.1016/j.jaut.2023.102994) (PMID:36706535)

Paterson, M., Johnston, W., Sherriff, A. and Culshaw, S. (2023) Periodontal instrumentation technique: an exploratory analysis of clinical outcomes and financial aspects. British Dental Journal, (doi: 10.1038/s41415-022-5405-1) (PMID:36624308) (Early Online Publication)

2022

Burns, J. et al. (2022) A Health Inequalities Impact Assessment of the surveillance of COVID-19 in asymptomatic patients attending dental settings in Scotland. Community Dental Health, 39(4), pp. 254-259. (PMID:36283070)

Piela, K., Watson, P., Donnelly, R., Goulding, M., Henriquez, F. L., MacKay, W. and Culshaw, S. (2022) Aerosol reduction efficacy of different intra-oral suction devices during ultrasonic scaling and high-speed handpiece use. BMC Oral Health, 22, 388. (doi: 10.1186/s12903-022-02386-w) (PMID:36068515) (PMCID:PMC9447970)

Wemyss, C. et al. (2022) Improving participation and engagement with a COVID-19 surveillance programme in an outpatient setting. BMJ Open Quality, 11(1), e001700. (doi: 10.1136/bmjoq-2021-001700) (PMID:35347067) (PMCID:PMC8960458)

Brennan, M. T. et al. (2022) Efficacy and safety of a novel mucoadhesive clobetasol patch for treatment of erosive oral lichen planus: A phase 2 randomized clinical trial. Journal of Oral Pathology and Medicine, 51(1), pp. 86-97. (doi: 10.1111/jop.13270) (PMID:34907617)

2021

Conway, D.I. et al. (2021) SARS-CoV-2 positivity in asymptomatic-screened dental patients. Journal of Dental Research, 100(6), pp. 583-590. (doi: 10.1177/00220345211004849) (PMID:33779355) (PMCID:PMC8138329)

Johnston, W., Rosier, B.T., Artacho, A., Paterson, M., Piela, K., Delaney, C., Brown, J.L. , Ramage, G. , Mira, A. and Culshaw, S. (2021) Mechanical biofilm disruption causes microbial and immunological shifts in periodontitis patients. Scientific Reports, 11, 9796. (doi: 10.1038/s41598-021-89002-z) (PMID:33963212) (PMCID:PMC8105330)

Davison, E., Johnston, W., Piela, K., Rosier, B. T., Paterson, M., Mira, A. and Culshaw, S. (2021) The subgingival plaque microbiome, systemic antibodies against bacteria and citrullinated proteins following periodontal therapy. Pathogens, 10(2), 193. (doi: 10.3390/pathogens10020193) (PMID:33578802) (PMCID:PMC7916579)

2020

Johnston, W., Paterson, M., Piela, K. M., Davison, E., Simpson, A., Goulding, M., Ramage, G. , Sherriff, A. and Culshaw, S. (2020) The systemic inflammatory response following hand instrumentation versus ultrasonic instrumentation—a randomized controlled trial. Journal of Clinical Periodontology, 47(9), pp. 1087-1097. (doi: 10.1111/jcpe.13342) (PMID:32628781)

2019

Brown, J. L. , Johnston, W., Delaney, C., Short, B., Butcher, M. C., Young, T., Butcher, J., Riggio, M. , Culshaw, S. and Ramage, G. (2019) Polymicrobial oral biofilm models: simplifying the complex. Journal of Medical Microbiology, 68(11), pp. 1573-1584. (doi: 10.1099/jmm.0.001063) (PMID:31524581)

Reilly, R. J.R., Johnston, W. and Culshaw, S. (2019) Autoimmunity and the oral cavity. Current Oral Health Reports, 6(1), pp. 1-8. (doi: 10.1007/s40496-019-0203-9)

Brown, J. L. , Johnston, W., Delaney, C., Rajendran, R., Butcher, J., Khan, S., Bradshaw, D., Ramage, G. and Culshaw, S. (2019) Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells. Scientific Reports, 9, 15779. (doi: 10.1038/s41598-019-52115-7) (PMID:31673005) (PMCID:PMC6823452)

Ramage, G. et al. (2019) Impact of frequency of denture cleaning on microbial and clinical parameters - a bench to chairside approach. Journal of Oral Microbiology, 11(1), 1538437. (doi: 10.1080/20002297.2018.1538437) (PMID:30598732) (PMCID:PMC6225516)

2018

Brown, J.L. , Campbell, L., Malcolm, J. , Adrados Planell, A., Butcher, J.P. and Culshaw, S. (2018) Enrichment of innate lymphoid cell populations in gingival tissue. Journal of Dental Research, 97(12), pp. 1399-1405. (doi: 10.1177/0022034518782141) (PMID:29928824)

Taylor, G., Culshaw, S. , Armas, J., Savarrio, L. and Goodall, C. (2018) A case report of Parry Romberg Syndrome initially presenting as periodontitis. Oral Surgery, 11(2), pp. 131-135. (doi: 10.1111/ors.12315)

Simon-Soro, A., Sherriff, A. , Sadique, S., Ramage, G. , Macpherson, L. , Mira, A., Culshaw, S. and Malcolm, J. (2018) Combined analysis of the salivary microbiome and host defence peptides predicts dental disease. Scientific Reports, 8, 1484. (doi: 10.1038/s41598-018-20085-x) (PMID:29367728) (PMCID:PMC5784018)

2017

Culshaw, S. (2017) Peridontal disease: its impact on restorative dentistry. Primary Dental Journal, 6(1), pp. 25-31. (PMID:28376960)

Connolly, E., Millhouse, E., Doyle, R., Culshaw, S. , Ramage, G. and Moran, G.P. (2017) The Porphyromonas gingivalis hemagglutinins HagB and HagC are major mediators of adhesion and biofilm formation. Molecular Oral Microbiology, 32(1), pp. 35-47. (doi: 10.1111/omi.12151) (PMID:28051836)

Culshaw, S. (2017) Periodontal disease: its impact on restorative dentistry. Primary Dental Journal, 6(1), pp. 25-31. (PMID:28376960)

2016

Stephen, A. S., Millhouse, E., Sherry, L. , Aduse-Opoku, J., Culshaw, S. , Ramage, G. , Bradshaw, D. J., Burnett, G. R. and Allaker, R. P. (2016) In vitro effect of Porphyromonas gingivalis methionine gamma lyase on biofilm composition and oral inflammatory response. PLoS ONE, 11(12), e0169157. (doi: 10.1371/journal.pone.0169157) (PMID:28033374) (PMCID:PMC5199072)

Ramage, G. , Lappin, D.F., Millhouse, E., Malcolm, J. , Jose, A., Yang, J., Bradshaw, D.J., Pratten, J.R. and Culshaw, S. (2016) The epithelial cell response to health and disease associated oral biofilm models. Journal of Periodontal Research, 52(3), pp. 325-333. (doi: 10.1111/jre.12395) (PMID:27330034) (PMCID:PMC5412879)

Malcolm, J. et al. (2016) Mast cells contribute to Porphyromonas gingivalis–induced bone loss. Journal of Dental Research, 95(6), pp. 704-710. (doi: 10.1177/0022034516634630) (PMID:26933137)

Fisher, B. A. et al. (2016) Erratum to: Smoking, Porphyromonas gingivalis and the immune response to citrullinated autoantigens before the clinical onset of rheumatoid arthritis in a Southern European nested case–control study. BMC Musculoskeletal Disorders, 17, 62. (doi: 10.1186/s12891-016-0916-z) (PMID:26849877) (PMCID:PMC4744449)

Campbell, L., Millhouse, E., Malcolm, J. and Culshaw, S. (2016) T cells, teeth and tissue destruction - what do T cells do in periodontal disease? Molecular Oral Microbiology, 31(6), pp. 445-456. (doi: 10.1111/omi.12144) (PMID:26505640)

2015

Fisher, B. A. et al. (2015) Smoking, Porphyromonas gingivalis and the immune response to citrullinated autoantigens before the clinical onset of rheumatoid arthritis in a Southern European nested case–control study. BMC Musculoskeletal Disorders, 16, 331. (doi: 10.1186/s12891-015-0792-y) (PMID:26537917) (PMCID:PMC4634856)

Malcolm, J. et al. (2015) IL-33 exacerbates periodontal disease through induction of RANKL. Journal of Dental Research, 94(7), pp. 968-975. (doi: 10.1177/0022034515577815) (PMID:25808546)

Simón-Soro, Á., D’Auria, G., Collado, M. C., Džunková, M., Culshaw, S. and Mira, A. (2015) Revealing microbial recognition by specific antibodies. BMC Microbiology, 15, 132. (doi: 10.1186/s12866-015-0456-y) (PMID:26134992) (PMCID:PMC4489363)

Oliver-Bell, J., Butcher, J.P., Malcolm, J. , Macleod, M.K.L. , Adrados Planell, A., Campbell, L., Nibbs, R.J.B. , Garside, P. , McInnes, I.B. and Culshaw, S. (2015) Periodontitis in the absence of B cells and specific anti-bacterial antibody. Oral Microbiology and Immunology, 30(2), pp. 160-169. (doi: 10.1111/omi.12082) (PMID:25219939)

Shahzad, M., Millhouse, E., Culshaw, S. , Edwards, C. A. , Ramage, G. and Combet, E. (2015) Selected dietary (poly)phenols inhibit periodontal pathogen growth and biofilm formation. Food and Function, 6(3), pp. 719-729. (doi: 10.1039/C4FO01087F) (PMID:25585200)

Awang, R. A. et al. (2015) Erratum to: Clinical associations between IL-17 family cytokines and periodontitis and potential differential roles for IL-17A and IL-17E in periodontal immunity. Inflammation Research, 64(1), p. 83. (doi: 10.1007/s00011-014-0788-3)

2014

Azman, R. et al. (2014) Clinical associations between IL-17 family cytokines and periodontitis and potential differential roles for IL-17A and IL-17E in periodontal immunity. Inflammation Research, 63(12), pp. 1001-1012. (doi: 10.1007/s00011-014-0776-7) (PMID:25369802)

Millhouse, E., Jose, A., Sherry, L. , Lappin, D. F., Patel, N., Middleton, A. M., Pratten, J., Culshaw, S. and Ramage, G. (2014) Development of an in vitro periodontal biofilm model for assessing antimicrobial and host modulatory effects of bioactive molecules. BMC Oral Health, 14(1), p. 80. (doi: 10.1186/1472-6831-14-80)

Macpherson, A., Zoheir, N., Awang, R. A., Culshaw, S. , Ramage, G. , Lappin, D. F. and Nile, C. J. (2014) The alpha 7 nicotinic receptor agonist PHA-543613 hydrochloride inhibits Porphyromonas gingivalis-induced expression of interleukin-8 by oral keratinocytes. Inflammation Research, 63(7), pp. 557-568. (doi: 10.1007/s00011-014-0725-5)

Malcolm, J. , Sherriff, A. , Lappin, D. F., Ramage, G. , Conway, D. I. , Macpherson, L. M. and Culshaw, S. (2014) Salivary antimicrobial proteins associate with age-related changes in streptococcal composition in dental plaque. Molecular Oral Microbiology, 29(6), pp. 284-293. (doi: 10.1111/omi.12058)

Quirke, A.-M. et al. (2014) Heightened immune response to autocitrullinated porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis. Annals of the Rheumatic Diseases, 73(1), pp. 263-269. (doi: 10.1136/annrheumdis-2012-202726) (PMID:23463691) (PMCID:PMC3888615)

2013

Lappin, D.F., Apatzidou, D., Quirke, A.M., Oliver-Bell, J., Butcher, J.P., Kinane, D.F., Riggio, M.P. , Venables, P., McInnes, I.B. and Culshaw, S. (2013) Influence of periodontal disease, porphyromonas gingivalisand cigarette smoking on systemic anti-citrullinated peptide antibody titres. Journal of Clinical Periodontology, 40(10), pp. 907-915. (doi: 10.1111/jcpe.12138) (PMID:23902301)

Sherry, L. , Millhouse, E., Lappin, D. F., Murray, C., Culshaw, S. , Nile, C. J. and Ramage, G. (2013) Investigating the biological properties of carbohydrate derived fulvic acid (CHD-FA) as a potential novel therapy for the management of oral biofilm infections. BMC Oral Health, 13, p. 47. (doi: 10.1186/1472-6831-13-47)

2012

Ramage, G. , Milligan, S., Lappin, D. F., Sherry, L. , Sweeney, P., Williams, C., Bagg, J. and Culshaw, S. (2012) Antifungal, cytotoxic, and immunomodulatory properties of tea tree oil and its derivative components: potential role in management of oral candidosis in cancer patients. Frontiers in Microbiology, 3, p. 220. (doi: 10.3389/fmicb.2012.00220)

Farquharson, D., Butcher, J.P. and Culshaw, S. (2012) Periodontitis, porphyromonas, and the pathogenesis of rheumatoid arthritis. Mucosal Immunology, 5(2), pp. 112-120. (doi: 10.1038/mi.2011.66)

2011

Butcher, J.P., Malcolm, J. , Benson, R.A. , Deng, D.M., Brewer, J.M. , Garside, P. and Culshaw, S. (2011) Effects of streptococcus mutans on dendritic cell activation and function. Journal of Dental Research, 90(10), pp. 1221-1227. (doi: 10.1177/0022034511412970)

Culshaw, S. , McInnes, I. B. and Liew, F. Y. (2011) What can the periodontal community learn from the pathophysiology of rheumatoid arthritis? Journal of Clinical Periodontology, 38(S11), pp. 106-113. (doi: 10.1111/j.1600-051X.2010.01669.x) (PMID:21323707)

2010

Ramage, G. , Culshaw, S. , Jones, B. and Williams, C. (2010) Are we any closer to beating the biofilm: novel methods of biofilm control. Current Opinion in Infectious Diseases, 23(6), pp. 560-566. (doi: 10.1097/QCO.0b013e32833e5850) (PMID:20717027)

Wegner, N., Wait, R., Sroka, A., Eick, S., Nguyen, K.-A., Lundberg, K., Kinloch, A., Culshaw, S. , Potempa, J. and Venables, P.J. (2010) Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis. Arthritis and Rheumatism, 62(9), pp. 2662-2672. (doi: 10.1002/art.27552)

2008

Culshaw, S.E. , Millington, O.R., Brewer, J.M. and McInnes, I. (2008) Murine neutrophils present class II restricted antigen. Immunology Letters, 118(1), pp. 49-54. (doi: 10.1016/j.imlet.2008.02.008) (PMID:18400308) (PMCID:PMC2430030)

Nogueira, R. D., King, W. F., Gunda, G., Culshaw, S. , Taubman, M. A., Mattos-Graner, R. O. and Smith, D. J. (2008) Mutans Streptococcal infection induces salivary antibody to virulence proteins and associated functional domains. Infection and Immunity, 76(8), pp. 3606-3613. (doi: 10.1128/IAI.00214-08)

2007

Culshaw, S. , LaRosa, K., Tolani, H., Han, X., Eastcott, J. W., Smith, D. J. and Taubman, M. A. (2007) Immunogenic and protective potential of mutans streptococcal glucosyltransferase peptide constructs selected by major histocompatibility complex class II allele binding. Infection and Immunity, 75(2), pp. 915-923. (doi: 10.1128/IAI.01582-06)

2005

Culshaw, S. , Leung, B., Gracie, J., Campbell, C., Thomson, D., Gemmell, C., Liew, F. and McInnes, I. (2005) Prior elevation of IL-18 promotes rapid early IFN-gamma production during staphylococcal infection. European Journal of Immunology, 35, pp. 1438-1444. (doi: 10.1002/ejui.200425661) (PMID:15789357)

2004

Leung, B.P., Xu, D., Culshaw, S. , McInnes, I. B. and Liew, .Y. (2004) A novel therapy of murine collagen-induced arthritis with soluble T1/ST2. Journal of Immunology, 173(1), pp. 145-150. (doi: 10.4049/jimmunol.173.1.145) (PMID:15210768)

2003

Cannetti, C. O., Leung, B. P., Culshaw, S. , McInnes, I. B. , Cunha, F. Q. and Liew, F. Y. (2003) IL-18 enhances collagen-induced arthritis by recruiting neutrophils via TNF-alpha and leukotriene B-4. Journal of Immunology, 171, pp. 1009-1015. (doi: 10.4049/jimmunol.171.2.1009) (PMID:12847274)

2001

Leung, B. P., Culshaw, S. , Gracie, J. A., Hunter, D., Canetti, C. A., Campbell, C., Cunha, F., Liew, F. Y. and McInnes, I. B. (2001) A role for IL-18 in neutrophil activation. Journal of Immunology, 167, pp. 2879-2886. (doi: 10.4049/jimmunol.167.5.2879) (PMID:11509635)

This list was generated on Thu Apr 18 04:25:08 2024 BST.
Jump to: Articles
Number of items: 55.

Articles

Lopez‐Oliva, I., Malcolm, J. and Culshaw, S. (2024) Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases. Periodontology 2000, (doi: 10.1111/prd.12530) (Early Online Publication)

Rosier, B. T. et al. (2024) Publisher Correction: Nitrate reduction capacity of the oral microbiota is impaired in periodontitis: potential implications for systemic nitric oxide availability. International Journal of Oral Science, 16, 8. (doi: 10.1038/s41368-024-00283-2) (PMID:38272860) (PMCID:PMC10811215)

Aminu, A. Q. et al. (2023) Inequalities in access to NHS primary care dental services in Scotland during the COVID-19 pandemic. British Dental Journal, (doi: 10.1038/s41415-023-5856-z) (PMID:37225842) (PMCID:PMC10208681) (Early Online Publication)

Johnston, W. et al. (2023) Longitudinal changes in subgingival biofilm composition following periodontal treatment. Journal of Periodontology, (doi: 10.1002/JPER.22-0749) (PMID:36960491) (Early Online Publication)

Malcolm, J. et al. (2023) C-terminal citrullinated peptide alters antigen-specific APC:T cell interactions leading to breach of immune tolerance. Journal of Autoimmunity, 135, 102994. (doi: 10.1016/j.jaut.2023.102994) (PMID:36706535)

Paterson, M., Johnston, W., Sherriff, A. and Culshaw, S. (2023) Periodontal instrumentation technique: an exploratory analysis of clinical outcomes and financial aspects. British Dental Journal, (doi: 10.1038/s41415-022-5405-1) (PMID:36624308) (Early Online Publication)

Burns, J. et al. (2022) A Health Inequalities Impact Assessment of the surveillance of COVID-19 in asymptomatic patients attending dental settings in Scotland. Community Dental Health, 39(4), pp. 254-259. (PMID:36283070)

Piela, K., Watson, P., Donnelly, R., Goulding, M., Henriquez, F. L., MacKay, W. and Culshaw, S. (2022) Aerosol reduction efficacy of different intra-oral suction devices during ultrasonic scaling and high-speed handpiece use. BMC Oral Health, 22, 388. (doi: 10.1186/s12903-022-02386-w) (PMID:36068515) (PMCID:PMC9447970)

Wemyss, C. et al. (2022) Improving participation and engagement with a COVID-19 surveillance programme in an outpatient setting. BMJ Open Quality, 11(1), e001700. (doi: 10.1136/bmjoq-2021-001700) (PMID:35347067) (PMCID:PMC8960458)

Brennan, M. T. et al. (2022) Efficacy and safety of a novel mucoadhesive clobetasol patch for treatment of erosive oral lichen planus: A phase 2 randomized clinical trial. Journal of Oral Pathology and Medicine, 51(1), pp. 86-97. (doi: 10.1111/jop.13270) (PMID:34907617)

Conway, D.I. et al. (2021) SARS-CoV-2 positivity in asymptomatic-screened dental patients. Journal of Dental Research, 100(6), pp. 583-590. (doi: 10.1177/00220345211004849) (PMID:33779355) (PMCID:PMC8138329)

Johnston, W., Rosier, B.T., Artacho, A., Paterson, M., Piela, K., Delaney, C., Brown, J.L. , Ramage, G. , Mira, A. and Culshaw, S. (2021) Mechanical biofilm disruption causes microbial and immunological shifts in periodontitis patients. Scientific Reports, 11, 9796. (doi: 10.1038/s41598-021-89002-z) (PMID:33963212) (PMCID:PMC8105330)

Davison, E., Johnston, W., Piela, K., Rosier, B. T., Paterson, M., Mira, A. and Culshaw, S. (2021) The subgingival plaque microbiome, systemic antibodies against bacteria and citrullinated proteins following periodontal therapy. Pathogens, 10(2), 193. (doi: 10.3390/pathogens10020193) (PMID:33578802) (PMCID:PMC7916579)

Johnston, W., Paterson, M., Piela, K. M., Davison, E., Simpson, A., Goulding, M., Ramage, G. , Sherriff, A. and Culshaw, S. (2020) The systemic inflammatory response following hand instrumentation versus ultrasonic instrumentation—a randomized controlled trial. Journal of Clinical Periodontology, 47(9), pp. 1087-1097. (doi: 10.1111/jcpe.13342) (PMID:32628781)

Brown, J. L. , Johnston, W., Delaney, C., Short, B., Butcher, M. C., Young, T., Butcher, J., Riggio, M. , Culshaw, S. and Ramage, G. (2019) Polymicrobial oral biofilm models: simplifying the complex. Journal of Medical Microbiology, 68(11), pp. 1573-1584. (doi: 10.1099/jmm.0.001063) (PMID:31524581)

Reilly, R. J.R., Johnston, W. and Culshaw, S. (2019) Autoimmunity and the oral cavity. Current Oral Health Reports, 6(1), pp. 1-8. (doi: 10.1007/s40496-019-0203-9)

Brown, J. L. , Johnston, W., Delaney, C., Rajendran, R., Butcher, J., Khan, S., Bradshaw, D., Ramage, G. and Culshaw, S. (2019) Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells. Scientific Reports, 9, 15779. (doi: 10.1038/s41598-019-52115-7) (PMID:31673005) (PMCID:PMC6823452)

Ramage, G. et al. (2019) Impact of frequency of denture cleaning on microbial and clinical parameters - a bench to chairside approach. Journal of Oral Microbiology, 11(1), 1538437. (doi: 10.1080/20002297.2018.1538437) (PMID:30598732) (PMCID:PMC6225516)

Brown, J.L. , Campbell, L., Malcolm, J. , Adrados Planell, A., Butcher, J.P. and Culshaw, S. (2018) Enrichment of innate lymphoid cell populations in gingival tissue. Journal of Dental Research, 97(12), pp. 1399-1405. (doi: 10.1177/0022034518782141) (PMID:29928824)

Taylor, G., Culshaw, S. , Armas, J., Savarrio, L. and Goodall, C. (2018) A case report of Parry Romberg Syndrome initially presenting as periodontitis. Oral Surgery, 11(2), pp. 131-135. (doi: 10.1111/ors.12315)

Simon-Soro, A., Sherriff, A. , Sadique, S., Ramage, G. , Macpherson, L. , Mira, A., Culshaw, S. and Malcolm, J. (2018) Combined analysis of the salivary microbiome and host defence peptides predicts dental disease. Scientific Reports, 8, 1484. (doi: 10.1038/s41598-018-20085-x) (PMID:29367728) (PMCID:PMC5784018)

Culshaw, S. (2017) Peridontal disease: its impact on restorative dentistry. Primary Dental Journal, 6(1), pp. 25-31. (PMID:28376960)

Connolly, E., Millhouse, E., Doyle, R., Culshaw, S. , Ramage, G. and Moran, G.P. (2017) The Porphyromonas gingivalis hemagglutinins HagB and HagC are major mediators of adhesion and biofilm formation. Molecular Oral Microbiology, 32(1), pp. 35-47. (doi: 10.1111/omi.12151) (PMID:28051836)

Culshaw, S. (2017) Periodontal disease: its impact on restorative dentistry. Primary Dental Journal, 6(1), pp. 25-31. (PMID:28376960)

Stephen, A. S., Millhouse, E., Sherry, L. , Aduse-Opoku, J., Culshaw, S. , Ramage, G. , Bradshaw, D. J., Burnett, G. R. and Allaker, R. P. (2016) In vitro effect of Porphyromonas gingivalis methionine gamma lyase on biofilm composition and oral inflammatory response. PLoS ONE, 11(12), e0169157. (doi: 10.1371/journal.pone.0169157) (PMID:28033374) (PMCID:PMC5199072)

Ramage, G. , Lappin, D.F., Millhouse, E., Malcolm, J. , Jose, A., Yang, J., Bradshaw, D.J., Pratten, J.R. and Culshaw, S. (2016) The epithelial cell response to health and disease associated oral biofilm models. Journal of Periodontal Research, 52(3), pp. 325-333. (doi: 10.1111/jre.12395) (PMID:27330034) (PMCID:PMC5412879)

Malcolm, J. et al. (2016) Mast cells contribute to Porphyromonas gingivalis–induced bone loss. Journal of Dental Research, 95(6), pp. 704-710. (doi: 10.1177/0022034516634630) (PMID:26933137)

Fisher, B. A. et al. (2016) Erratum to: Smoking, Porphyromonas gingivalis and the immune response to citrullinated autoantigens before the clinical onset of rheumatoid arthritis in a Southern European nested case–control study. BMC Musculoskeletal Disorders, 17, 62. (doi: 10.1186/s12891-016-0916-z) (PMID:26849877) (PMCID:PMC4744449)

Campbell, L., Millhouse, E., Malcolm, J. and Culshaw, S. (2016) T cells, teeth and tissue destruction - what do T cells do in periodontal disease? Molecular Oral Microbiology, 31(6), pp. 445-456. (doi: 10.1111/omi.12144) (PMID:26505640)

Fisher, B. A. et al. (2015) Smoking, Porphyromonas gingivalis and the immune response to citrullinated autoantigens before the clinical onset of rheumatoid arthritis in a Southern European nested case–control study. BMC Musculoskeletal Disorders, 16, 331. (doi: 10.1186/s12891-015-0792-y) (PMID:26537917) (PMCID:PMC4634856)

Malcolm, J. et al. (2015) IL-33 exacerbates periodontal disease through induction of RANKL. Journal of Dental Research, 94(7), pp. 968-975. (doi: 10.1177/0022034515577815) (PMID:25808546)

Simón-Soro, Á., D’Auria, G., Collado, M. C., Džunková, M., Culshaw, S. and Mira, A. (2015) Revealing microbial recognition by specific antibodies. BMC Microbiology, 15, 132. (doi: 10.1186/s12866-015-0456-y) (PMID:26134992) (PMCID:PMC4489363)

Oliver-Bell, J., Butcher, J.P., Malcolm, J. , Macleod, M.K.L. , Adrados Planell, A., Campbell, L., Nibbs, R.J.B. , Garside, P. , McInnes, I.B. and Culshaw, S. (2015) Periodontitis in the absence of B cells and specific anti-bacterial antibody. Oral Microbiology and Immunology, 30(2), pp. 160-169. (doi: 10.1111/omi.12082) (PMID:25219939)

Shahzad, M., Millhouse, E., Culshaw, S. , Edwards, C. A. , Ramage, G. and Combet, E. (2015) Selected dietary (poly)phenols inhibit periodontal pathogen growth and biofilm formation. Food and Function, 6(3), pp. 719-729. (doi: 10.1039/C4FO01087F) (PMID:25585200)

Awang, R. A. et al. (2015) Erratum to: Clinical associations between IL-17 family cytokines and periodontitis and potential differential roles for IL-17A and IL-17E in periodontal immunity. Inflammation Research, 64(1), p. 83. (doi: 10.1007/s00011-014-0788-3)

Azman, R. et al. (2014) Clinical associations between IL-17 family cytokines and periodontitis and potential differential roles for IL-17A and IL-17E in periodontal immunity. Inflammation Research, 63(12), pp. 1001-1012. (doi: 10.1007/s00011-014-0776-7) (PMID:25369802)

Millhouse, E., Jose, A., Sherry, L. , Lappin, D. F., Patel, N., Middleton, A. M., Pratten, J., Culshaw, S. and Ramage, G. (2014) Development of an in vitro periodontal biofilm model for assessing antimicrobial and host modulatory effects of bioactive molecules. BMC Oral Health, 14(1), p. 80. (doi: 10.1186/1472-6831-14-80)

Macpherson, A., Zoheir, N., Awang, R. A., Culshaw, S. , Ramage, G. , Lappin, D. F. and Nile, C. J. (2014) The alpha 7 nicotinic receptor agonist PHA-543613 hydrochloride inhibits Porphyromonas gingivalis-induced expression of interleukin-8 by oral keratinocytes. Inflammation Research, 63(7), pp. 557-568. (doi: 10.1007/s00011-014-0725-5)

Malcolm, J. , Sherriff, A. , Lappin, D. F., Ramage, G. , Conway, D. I. , Macpherson, L. M. and Culshaw, S. (2014) Salivary antimicrobial proteins associate with age-related changes in streptococcal composition in dental plaque. Molecular Oral Microbiology, 29(6), pp. 284-293. (doi: 10.1111/omi.12058)

Quirke, A.-M. et al. (2014) Heightened immune response to autocitrullinated porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis. Annals of the Rheumatic Diseases, 73(1), pp. 263-269. (doi: 10.1136/annrheumdis-2012-202726) (PMID:23463691) (PMCID:PMC3888615)

Lappin, D.F., Apatzidou, D., Quirke, A.M., Oliver-Bell, J., Butcher, J.P., Kinane, D.F., Riggio, M.P. , Venables, P., McInnes, I.B. and Culshaw, S. (2013) Influence of periodontal disease, porphyromonas gingivalisand cigarette smoking on systemic anti-citrullinated peptide antibody titres. Journal of Clinical Periodontology, 40(10), pp. 907-915. (doi: 10.1111/jcpe.12138) (PMID:23902301)

Sherry, L. , Millhouse, E., Lappin, D. F., Murray, C., Culshaw, S. , Nile, C. J. and Ramage, G. (2013) Investigating the biological properties of carbohydrate derived fulvic acid (CHD-FA) as a potential novel therapy for the management of oral biofilm infections. BMC Oral Health, 13, p. 47. (doi: 10.1186/1472-6831-13-47)

Ramage, G. , Milligan, S., Lappin, D. F., Sherry, L. , Sweeney, P., Williams, C., Bagg, J. and Culshaw, S. (2012) Antifungal, cytotoxic, and immunomodulatory properties of tea tree oil and its derivative components: potential role in management of oral candidosis in cancer patients. Frontiers in Microbiology, 3, p. 220. (doi: 10.3389/fmicb.2012.00220)

Farquharson, D., Butcher, J.P. and Culshaw, S. (2012) Periodontitis, porphyromonas, and the pathogenesis of rheumatoid arthritis. Mucosal Immunology, 5(2), pp. 112-120. (doi: 10.1038/mi.2011.66)

Butcher, J.P., Malcolm, J. , Benson, R.A. , Deng, D.M., Brewer, J.M. , Garside, P. and Culshaw, S. (2011) Effects of streptococcus mutans on dendritic cell activation and function. Journal of Dental Research, 90(10), pp. 1221-1227. (doi: 10.1177/0022034511412970)

Culshaw, S. , McInnes, I. B. and Liew, F. Y. (2011) What can the periodontal community learn from the pathophysiology of rheumatoid arthritis? Journal of Clinical Periodontology, 38(S11), pp. 106-113. (doi: 10.1111/j.1600-051X.2010.01669.x) (PMID:21323707)

Ramage, G. , Culshaw, S. , Jones, B. and Williams, C. (2010) Are we any closer to beating the biofilm: novel methods of biofilm control. Current Opinion in Infectious Diseases, 23(6), pp. 560-566. (doi: 10.1097/QCO.0b013e32833e5850) (PMID:20717027)

Wegner, N., Wait, R., Sroka, A., Eick, S., Nguyen, K.-A., Lundberg, K., Kinloch, A., Culshaw, S. , Potempa, J. and Venables, P.J. (2010) Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis. Arthritis and Rheumatism, 62(9), pp. 2662-2672. (doi: 10.1002/art.27552)

Culshaw, S.E. , Millington, O.R., Brewer, J.M. and McInnes, I. (2008) Murine neutrophils present class II restricted antigen. Immunology Letters, 118(1), pp. 49-54. (doi: 10.1016/j.imlet.2008.02.008) (PMID:18400308) (PMCID:PMC2430030)

Nogueira, R. D., King, W. F., Gunda, G., Culshaw, S. , Taubman, M. A., Mattos-Graner, R. O. and Smith, D. J. (2008) Mutans Streptococcal infection induces salivary antibody to virulence proteins and associated functional domains. Infection and Immunity, 76(8), pp. 3606-3613. (doi: 10.1128/IAI.00214-08)

Culshaw, S. , LaRosa, K., Tolani, H., Han, X., Eastcott, J. W., Smith, D. J. and Taubman, M. A. (2007) Immunogenic and protective potential of mutans streptococcal glucosyltransferase peptide constructs selected by major histocompatibility complex class II allele binding. Infection and Immunity, 75(2), pp. 915-923. (doi: 10.1128/IAI.01582-06)

Culshaw, S. , Leung, B., Gracie, J., Campbell, C., Thomson, D., Gemmell, C., Liew, F. and McInnes, I. (2005) Prior elevation of IL-18 promotes rapid early IFN-gamma production during staphylococcal infection. European Journal of Immunology, 35, pp. 1438-1444. (doi: 10.1002/ejui.200425661) (PMID:15789357)

Leung, B.P., Xu, D., Culshaw, S. , McInnes, I. B. and Liew, .Y. (2004) A novel therapy of murine collagen-induced arthritis with soluble T1/ST2. Journal of Immunology, 173(1), pp. 145-150. (doi: 10.4049/jimmunol.173.1.145) (PMID:15210768)

Cannetti, C. O., Leung, B. P., Culshaw, S. , McInnes, I. B. , Cunha, F. Q. and Liew, F. Y. (2003) IL-18 enhances collagen-induced arthritis by recruiting neutrophils via TNF-alpha and leukotriene B-4. Journal of Immunology, 171, pp. 1009-1015. (doi: 10.4049/jimmunol.171.2.1009) (PMID:12847274)

Leung, B. P., Culshaw, S. , Gracie, J. A., Hunter, D., Canetti, C. A., Campbell, C., Cunha, F., Liew, F. Y. and McInnes, I. B. (2001) A role for IL-18 in neutrophil activation. Journal of Immunology, 167, pp. 2879-2886. (doi: 10.4049/jimmunol.167.5.2879) (PMID:11509635)

This list was generated on Thu Apr 18 04:25:08 2024 BST.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Patient-public involvement in dental research
    NHS Greater Glasgow and Clyde
    2022 - 2023
     
  • The ENHANCE-D Study - ENHANCing smoking cEssation interventions in Dentistry
    National Institute for Health Research
    2021 - 2024
     
  • Continuation of covid surveillance in dental settings
    Public Health Scotland
    2020 - 2021
     
  • Covid-19 community surveillance in dental centres across Scotland.
    Health Protection Scotland
    2020 - 2021
     
  • Investigating changes in nitrate-reducing bacteria after non-surgical periodontal therapy A pilot study to assess the effects of non-surgical periodontal therapy on nitrate reducing bacteria in the dental plaque microbiome.
    Oral and Dental Research Trust
    2019 - 2021
     
  • Mucosal Postcodes - Understanding T-Cell Trafficking in the Oral Mucosa
    Medical Research Council (MRC)
    2019 - 2022
     
  • Do biological anti-resorptive treatments for osteoporosis impact oral health
    NHS Greater Glasgow and Clyde Endowment Funds
    2018 - 2019
     
  • Understanding Gingival Leukocyte Address Codes
    Oral and Dental Research Trust
    2017 - 2018
     
  • Investigating the immune response to citrullinated antigen
    Arthritis Research UK
    2015 - 2018
     
  • The biology of social inequality: an investigation of the interaction between social and biological factors and dental disease in Scottish preschool children
    Glasgow Children`s Hospital Charity
    2014 - 2015
     
  • Development of bioinformatic analysis pipelines to integrate transcriptomic and metabolomic data to map the alpha 7 nicotinic receptor... (ISSF Catalyst)
    Wellcome Trust
    2013 - 2014
     
  • The role of mast cells in inflammation initiated in the oral mucosa
    Chief Scientist Office
    2012 - 2013
     
  • Do age-related changes in acetylcholine production by oral keratinocytes impact on the pathogenesis of peridontal disease?
    Dunhill Medical Trust
    2012 - 2014
     
  • RAPID: Rheumatoid arthritis and periodonteal inflammatory disease
    European Commission
    2012 - 2016
     
  • Scottish Senior Clinical Fellowship Scheme J22731 MVM
    Scottish Funding Council
    2012 - 2016
     
  • What is the role of Interleukin-33 in periodontal disease
    Royal College of Surgeons of Edinburgh
    2011 - 2012
     
  • Characterisation of T cell differentiation in response to the periodontal pathogen Porthyromonas gingivalis.
    Oral and Dental Research Trust
    2011 - 2012
     
  • Does IL-17E have a regulatory role in periodontal disease via effects on oral keratinocytes?
    Tenovus Scotland
    2011 - 2012
     
  • Gums and Joints
    European Commission
    2010 - 2014
     
  • Dissecting the adaptive immune response to cariogenic bacteria in the oral cavity
    Wellcome Trust
    2010 - 2010
     
  • Inflammatory mediators in periodontal disease
    British Society of Periodontology
    2010 - 2010
     
  • The Inflammatory Response to Periodontal Pathogens
    Microbiology Society
    2010 - 2010
     
  • Cytokines in periodontal disease
    Royal College of Physicians & Surgeons of Glasgow
    2009 - 2010
     
  • Dissecting the adaptive immune response to cariogenic bacteria in the oral cavity
    Medical Research Scotland
    2009 - 2010
     
  • The relationship betweeen the host response and oral biofilm development
    Tenovus Scotland
    2009 - 2010
     
  • Dissecting the role of the human Th17 cell in chronic inflammation
    British Society of Periodontology
    2008 - 2009
     

Supervision

  • Piela, Krystyna
    Holding the front line – maintaining barrier integrity in the mouth

Shauna Culshaw