Dr Sarah Meek

  • Lecturer (Medicine)
  • Associate (Institute of Cancer Sciences)

telephone: 01413307549
email: Sarah.Meek@glasgow.ac.uk

School of Medicine, Dentistry & Nursing, Undergraduate Medical School, Room 507, Wolfson Medical School Building, Gilmorehill Campus, Glasgow, G12 8QQ

Research interests

 

Current Teaching

  • Fellow of the Institute for Learning and Teaching in Higher Education
  • Co-Lead Educator for Glasgow University’s first MOOC (massive open online course), ‘Cancer in the 21st Century – the Genomic Revolution’
  • MSc Translational Medical Sciences
  • MSc Cancer Sciences
  • MRes Molecular Medicine
    - Deputy Director; Introductory Course Co-Coordinator; Tutorial Series and Research Placement Coordinator; teacher
  • PhD Thesis Committee Member and Advisor
  • Undergraduate MBChB programme
    - Year 2 / Phase 2 MBChB Endocrinology Coordinator; Years 1 & 2 PBL facilitator; Years 1 & 2 assessment
  • Pre-Masters in Medical Science
  • Non-University teaching / outreach in secondary schools and at Glasgow and Edinburgh Science Festivals

Current Scholarship Interests

  • Threshold concepts in learning and teaching
  • Medical & science education
  • Interdisciplinary education
  • MOOCs and e-learning

Publications

  • University of Glasgow Learning and Teaching Conference, April 2014
    Poster: The Making of a MOOC: Reflections from the Journey
    Leah Marks, Sarah Meek, Camille Huser and Louise Blakemore

    Massive Open Online Courses (MOOCs) have been variously hailed as ‘the next big thing’ in education or a ‘bubble waiting to burst’. “Cancer in the 21st Century - The Genomic Revolution” is the University of Glasgow’s first MOOC. It lasts six weeks and is divided into six key topics, covering the past, present and future of cancer causes, diagnosis and treatment. The MOOC is hosted on Futurelearn (FL), the first UK-based provider. We summarise the lessons we have learned in developing this course, and highlight issues for further consideration.

  • 6th  NAIRTL Annual Conference  / 4th Biennial International Threshold Concepts Conference, Dublin, Ireland, July 2012
    Poster: Threshold Concepts and Troublesome Knowledge in the First Year Curriculum at a UK Medical School
    Sarah Meek and Susan Jamieson

    In Meyer and Land’s model, Threshold Concepts (TCs) are ‘gateway’ concepts which students must grasp in order for subsequent higher-level learning. They are often troublesome for students to learn, and for staff to teach well. This study used qualitative analysis of questionnaire and interview data to identify several areas that experienced staff regard as ‘troublesome’ for students in the first year of a Problem-based learning (PBL) curriculum at a UK Medical School.

    We identified several troublesome areas, of which several map to previously-proposed TCs, including scale, dynamics (spatial and temporal), integration and link-making, equilibrium, metalearning, and discipline-based ways of organising and using knowledge. Additional areas, such as the Hierarchy of Systems model, a systems approach to integrating different medical disciplines, and specific skills, were also identified, and we discuss whether these indicate novel TCs. Several of the areas identified as troublesome are central to non-judgemental, patient-centred practice, which is a GMC requirement in medical training and professional development. Finally, we identified mathematical and spatio-temporal models, analogies, appropriate assessments, experiential and contextual learning, and staff modelling, as teaching methods that staff can use to help students grasp troublesome areas.

    View poster published in conference proceedings here [15mb PDF].

  • Watkins JL, Lewandowski KT, Meek SE, Storz P, Toker A, Piwnica-Worms H. 2008 Proc Natl Acad Sci U S A. 105(47):18378-83.  Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association.
  • Eckert M, Meek SE, Ball KL. 2006 J Biol Chem. 281(32):23092-102. A novel repressor domain is required for maximal growth inhibition by the IRF-1 tumor suppressor.
  • Harthill JE, Meek SE, Morrice N, Peggie MW, Borch J, Wong BH, Mackintosh C. 2006 Plant J. 47(2):211-23. Phosphorylation and 14-3-3 binding of Arabidopsis trehalose-phosphate synthase 5 in response to 2-deoxyglucose.

  • Puc J, Keniry M, Li HS, Pandita TK, Choudhury AD, Memeo L, Mansukhani M, Murty VV, Gaciong Z, Meek SE, Piwnica-Worms H, Hibshoosh H, Parsons R. 2005 Cancer Cell. 7(2):193-204. Lack of PTEN sequesters CHK1 and initiates genetic instability.
  • Meek SE, Lane WS, Piwnica-Worms H. 2004 J Biol Chem. 279(31):32046-54. Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.
  • Kulma A, Villadsen D, Campbell DG, Meek SE, Harthill JE, Nielsen TH, MacKintosh C. 2004 Plant J. 37(5):654-67. Phosphorylation and 14-3-3 binding of Arabidopsis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
  • Moorhead GB, Meek SE, Douglas P, Bridges D, Smith CS, Morrice N, MacKintosh C. 2003  Eur J. Biochem 270(6):1356-62. Purification of a plant nucleotide pyrophosphatase as a protein that interferes with nitrate reductase and glutamine synthetase assays.
  • Bulavin DV, Higashimoto Y, Demidenko ZN, Meek S, Graves P, Phillips C, Zhao H, Moody SA, Appella E, Piwnica-Worms H, Fornace AJ 2003 Nature Cell Biol. 5(6):545-51. Dual phosphorylation controls Cdc25 phosphatases .and mitotic entry.
  • MacKintosh C, Meek SE. 2001 Cell Mol Life Sci. 58(2):205-14. Regulation of plant NR activity by reversible phosphorylation, 14-3-3 proteins and proteolysis.
  • *Cotelle V, *Meek SE, Provan F, Milne FC, Morrice N, MacKintosh C. 2000 EMBO J. 19(12):2869-76. 14-3-3s regulate global cleavage of their diverse binding partners in sugar-starved Arabidopsis cells (*joint first authors)
  • Meek S, Morrice N, MacKintosh C. 1999 FEBS Lett. 457(3):494-8. Microcystin affinity purification of plant protein phosphatases: PP1C, PP5 and a regulatory A-subunit of PP2A.
  • Moorhead G, Douglas P, Cotelle V, Harthill J, Morrice N, Meek S, Deiting U, Stitt M, Scarabel M, Aitken A, MacKintosh C. 1999 Plant J. 18(1):1-12. Phosphorylation-dependent interactions between enzymes of plant metabolism and 14-3-3 proteins.

Publications

List by: Type | Date

Jump to: 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2010 | 2008 | 2006 | 2005 | 2004 | 2003 | 2001 | 2000 | 1999
Number of items: 28.

2020

Blakemore, L. M., Meek, S. E.M. and Marks, L. K. (2020) Equipping learners to evaluate online health care resources: longitudinal study of learning design strategies in a health care massive open online course. Journal of Medical Internet Research, 22(2), e15177. (doi: 10.2196/15177)

Meek, S. E.M., Neve, H. and Wearn, A. (2020) Threshold concepts and troublesome knowledge. In: Netsel, D., Reedy, G., McKenna, L. and Gough, S. (eds.) Clinical Education for the Health Professions: Theory and Practice. Springer: Singapore. ISBN 9789811533433 (doi:10.1007/978-981-13-6106-7_25-1)

2019

Huser, C. , Marks, L., Linn, A. and Meek, S. (2019) Student-created online teaching resources for students. In: Rea, P. M. (ed.) Biomedical Visualisation, Volume 4. Series: Advances in experimental medicine and biology (1171). Springer International Publishing: Cham, pp. 37-46. ISBN 9783030242800 (doi:10.1007/978-3-030-24281-7_4)

Neve, H. and Meek, S. (2019) Is Self-Regulated Learning a Threshold Concept? An Audio-Diary Study of PBL in Two UK Medical Schools. AMEE 2019, Vienna, Austria, 24-28 Aug 2019. p. 368.

Grant, R., McKernan, M., Meek, S., Huser, C. and Jamieson, S. (2019) Audit of Representation of Protected Characteristics in Learning Materials in a Block of the MBChB. 9th National Scottish Medical Education Conference, Edinburgh, UK, 9-10 May 2019.

Grant, R., Huser, C. , McKernan, M. and Meek, S. (2019) Representation of Protected Characteristics in the Undergraduate Medical Curriculum: a Pilot Audit​. 9th National Scottish Medical Education Conference, Edinburgh, UK, 09-10 May 2019.

2018

Meek, S., Gilbert, K. and Neve, H. (2018) Using the Threshold Concept Framework to Explore Student Learning by PBL in Two UK Medical Schools. ISSOTL18: Toward a Learning Culture, Bergen, Norway, 24-27 Oct 2018.

Marks, L. and Meek, S. (2018) Blending MOOCs into medical education. MedEdPublish, 7(1), pp. 60-63. (doi: 10.15694/mep.2018.0000060.1)

2017

Meek, S. E.M., Blakemore, L. and Marks, L. (2017) Is peer review an appropriate form of assessment in a MOOC? Student participation and performance in formative peer review. Assessment and Evaluation in Higher Education, 42(6), pp. 1000-1013. (doi: 10.1080/02602938.2016.1221052)

2016

Marks, L., Meek, S., Huser, C. and Blakemore, L. (2016) Playing the Numbers Game: Students as Assessors in a MOOC Context. 9th Annual University of Glasgow Learning and Teaching Conference, Glasgow, UK, 12 Apr 2016.

Marks, L., Meek, S. and Jackson, M. (2016) Using MOOCs to Increase Exposure to Genomics in an Undergraduate Medical Curriculum. The European Human Genetics Conference 2016, Barcelona, Spain, 21-24 May 2016.

Marks, L., Meek, S. and Jackson, M. (2016) What to do with a MOOC? Using the Latest e-Learning Trend to Enhance Medical Education. HEA Health and Social Care Conference, Glasgow, UK, 24-25 Feb 2016.

2015

Meek, S., Marks, L. and Blakemore, L. (2015) Is Peer Review an Appropriate Assessment and Feedback Tool for a MOOC? AMEE eLearning Symposium, Glasgow, Scotland, 06-09 Sep 2015.

2014

Marks, L., Meek, S., Huser, C. and Blakemore, L. (2014) The Making of a MOOC: Reflections from the Journey! 7th Annual University of Glasgow Learning and Teaching Conference, Glasgow, UK, 10 Apr 2014.

Meek, S. and Jamieson, S. (2014) Threshold concepts and troublesome knowledge in the first year curriculum at a UK medical school [Poster]. In: O'Mahoney, C., Buchanan, A., O'Rourke, M. and Higgs, B. (eds.) Threshold Concepts: from Personal Practice to Communities of Practice: Proceedings of the National Academy’s Sixth Annual Conference and the Fourth Biennial Threshold Concepts Conference. NAIRTL. ISBN 9781906642594

2010

Narayan, V., Meek, S. E.M. and Ball, K. L. (2010) p53 and Immunity. In: Ayed, A. and Hupp, T. (eds.) p53. Series: Molecular biology intelligence unit. Springer: Boston, MA, pp. 178-186. ISBN 9781441982315 (doi:10.1007/978-1-4419-8231-5_12)

2008

Watkins, J. L., Lewandowski, K. T., Meek, S. E.M., Storz, P., Toker, A. and Piwnica-Worms, H. (2008) Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association. Proceedings of the National Academy of Sciences of the United States of America, 105(47), pp. 18378-18383. (doi: 10.1073/pnas.0809661105)

2006

Eckert, M., Meek, S. E.M. and Ball, K. L. (2006) A novel repressor domain is required for maximal growth inhibition by the IRF-1 tumor suppressor. Journal of Biological Chemistry, 281(32), pp. 23092-23102. (doi: 10.1074/jbc.M512589200)

Harthill, J. E., Meek, S. E.M., Morrice, N., Peggie, M. W., Borch, J., Wong, B. H. C. and MacKintosh, C. (2006) Phosphorylation and 14-3-3 binding of Arabidopsis trehalose-phosphate synthase 5 in response to 2-deoxyglucose. Plant Journal, 47(2), pp. 211-223. (doi: 10.1111/j.1365-313X.2006.02780.x)

2005

Puc, J. et al. (2005) Lack of PTEN sequesters CHK1 and initiates genetic instability. Cancer Cell, 7(2), pp. 193-204. (doi: 10.1016/j.ccr.2005.01.009)

2004

Kulma, A., Villadsen, D., Campbell, D. G., Meek, S. E.M., Harthill, J. E., Nielsen, T. H. and MacKintosh, C. (2004) Phosphorylation and 14-3-3 binding of Arabidopsis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Plant Journal, 37(5), pp. 654-667. (doi: 10.1111/j.1365-313X.2003.01992.x)

Meek, S. E.M., Lane, W. S. and Piwnica-Worms, H. (2004) Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins. Journal of Biological Chemistry, 279(31), pp. 32046-32054. (doi: 10.1074/jbc.M403044200)

2003

Bulavin, D. V. et al. (2003) Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nature Cell Biology, 5(6), pp. 545-551. (doi: 10.1038/ncb994)

Moorhead, G. B.G., Meek, S. E.M., Douglas, P., Bridges, D., Smith, C. S., Morrice, N. and MacKintosh, C. (2003) Purification of a plant nucleotide pyrophosphatase as a protein that interferes with nitrate reductase and glutamine synthetase assays. European Journal of Biochemistry, 270(6), pp. 1356-1362. (doi: 10.1046/j.1432-1033.2003.03509.x)

2001

MacKintosh, C. and Meek, S.E.M. (2001) Regulation of plant NR activity by reversible phosphorylation, 14-3-3 proteins and proteolysis. Cellular and Molecular Life Sciences, 58(2), pp. 205-214. (doi: 10.1007/PL00000848)

2000

Cotelle, V., Meek, S. E.M., Provan, F., Milne, F. C., Morrice, N. and MacKintosh, C. (2000) 14-3-3s regulate global cleavage of their diverse binding partners in sugar-starved Arabidopsis cells. EMBO Journal, 19(12), pp. 2869-2876. (doi: 10.1093/emboj/19.12.2869)

1999

Meek, S., Morrice, N. and MacKintosh, C. (1999) Microcystin affinity purification of plant protein phosphatases: PP1C, PP5 and a regulatory A-subunit of PP2A. FEBS Letters, 457(3), pp. 494-498. (doi: 10.1016/S0014-5793(99)01093-5)

Moorhead, G. et al. (1999) Phosphorylation-dependent interactions between enzymes of plant metabolism and 14-3-3 proteins. Plant Journal, 18(1), pp. 1-12. (doi: 10.1046/j.1365-313X.1999.00417.x)

This list was generated on Sat Sep 18 19:19:09 2021 BST.
Number of items: 28.

Articles

Blakemore, L. M., Meek, S. E.M. and Marks, L. K. (2020) Equipping learners to evaluate online health care resources: longitudinal study of learning design strategies in a health care massive open online course. Journal of Medical Internet Research, 22(2), e15177. (doi: 10.2196/15177)

Marks, L. and Meek, S. (2018) Blending MOOCs into medical education. MedEdPublish, 7(1), pp. 60-63. (doi: 10.15694/mep.2018.0000060.1)

Meek, S. E.M., Blakemore, L. and Marks, L. (2017) Is peer review an appropriate form of assessment in a MOOC? Student participation and performance in formative peer review. Assessment and Evaluation in Higher Education, 42(6), pp. 1000-1013. (doi: 10.1080/02602938.2016.1221052)

Watkins, J. L., Lewandowski, K. T., Meek, S. E.M., Storz, P., Toker, A. and Piwnica-Worms, H. (2008) Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association. Proceedings of the National Academy of Sciences of the United States of America, 105(47), pp. 18378-18383. (doi: 10.1073/pnas.0809661105)

Eckert, M., Meek, S. E.M. and Ball, K. L. (2006) A novel repressor domain is required for maximal growth inhibition by the IRF-1 tumor suppressor. Journal of Biological Chemistry, 281(32), pp. 23092-23102. (doi: 10.1074/jbc.M512589200)

Harthill, J. E., Meek, S. E.M., Morrice, N., Peggie, M. W., Borch, J., Wong, B. H. C. and MacKintosh, C. (2006) Phosphorylation and 14-3-3 binding of Arabidopsis trehalose-phosphate synthase 5 in response to 2-deoxyglucose. Plant Journal, 47(2), pp. 211-223. (doi: 10.1111/j.1365-313X.2006.02780.x)

Puc, J. et al. (2005) Lack of PTEN sequesters CHK1 and initiates genetic instability. Cancer Cell, 7(2), pp. 193-204. (doi: 10.1016/j.ccr.2005.01.009)

Kulma, A., Villadsen, D., Campbell, D. G., Meek, S. E.M., Harthill, J. E., Nielsen, T. H. and MacKintosh, C. (2004) Phosphorylation and 14-3-3 binding of Arabidopsis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Plant Journal, 37(5), pp. 654-667. (doi: 10.1111/j.1365-313X.2003.01992.x)

Meek, S. E.M., Lane, W. S. and Piwnica-Worms, H. (2004) Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins. Journal of Biological Chemistry, 279(31), pp. 32046-32054. (doi: 10.1074/jbc.M403044200)

Bulavin, D. V. et al. (2003) Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nature Cell Biology, 5(6), pp. 545-551. (doi: 10.1038/ncb994)

Moorhead, G. B.G., Meek, S. E.M., Douglas, P., Bridges, D., Smith, C. S., Morrice, N. and MacKintosh, C. (2003) Purification of a plant nucleotide pyrophosphatase as a protein that interferes with nitrate reductase and glutamine synthetase assays. European Journal of Biochemistry, 270(6), pp. 1356-1362. (doi: 10.1046/j.1432-1033.2003.03509.x)

MacKintosh, C. and Meek, S.E.M. (2001) Regulation of plant NR activity by reversible phosphorylation, 14-3-3 proteins and proteolysis. Cellular and Molecular Life Sciences, 58(2), pp. 205-214. (doi: 10.1007/PL00000848)

Cotelle, V., Meek, S. E.M., Provan, F., Milne, F. C., Morrice, N. and MacKintosh, C. (2000) 14-3-3s regulate global cleavage of their diverse binding partners in sugar-starved Arabidopsis cells. EMBO Journal, 19(12), pp. 2869-2876. (doi: 10.1093/emboj/19.12.2869)

Meek, S., Morrice, N. and MacKintosh, C. (1999) Microcystin affinity purification of plant protein phosphatases: PP1C, PP5 and a regulatory A-subunit of PP2A. FEBS Letters, 457(3), pp. 494-498. (doi: 10.1016/S0014-5793(99)01093-5)

Moorhead, G. et al. (1999) Phosphorylation-dependent interactions between enzymes of plant metabolism and 14-3-3 proteins. Plant Journal, 18(1), pp. 1-12. (doi: 10.1046/j.1365-313X.1999.00417.x)

Book Sections

Meek, S. E.M., Neve, H. and Wearn, A. (2020) Threshold concepts and troublesome knowledge. In: Netsel, D., Reedy, G., McKenna, L. and Gough, S. (eds.) Clinical Education for the Health Professions: Theory and Practice. Springer: Singapore. ISBN 9789811533433 (doi:10.1007/978-981-13-6106-7_25-1)

Huser, C. , Marks, L., Linn, A. and Meek, S. (2019) Student-created online teaching resources for students. In: Rea, P. M. (ed.) Biomedical Visualisation, Volume 4. Series: Advances in experimental medicine and biology (1171). Springer International Publishing: Cham, pp. 37-46. ISBN 9783030242800 (doi:10.1007/978-3-030-24281-7_4)

Meek, S. and Jamieson, S. (2014) Threshold concepts and troublesome knowledge in the first year curriculum at a UK medical school [Poster]. In: O'Mahoney, C., Buchanan, A., O'Rourke, M. and Higgs, B. (eds.) Threshold Concepts: from Personal Practice to Communities of Practice: Proceedings of the National Academy’s Sixth Annual Conference and the Fourth Biennial Threshold Concepts Conference. NAIRTL. ISBN 9781906642594

Narayan, V., Meek, S. E.M. and Ball, K. L. (2010) p53 and Immunity. In: Ayed, A. and Hupp, T. (eds.) p53. Series: Molecular biology intelligence unit. Springer: Boston, MA, pp. 178-186. ISBN 9781441982315 (doi:10.1007/978-1-4419-8231-5_12)

Conference or Workshop Item

Neve, H. and Meek, S. (2019) Is Self-Regulated Learning a Threshold Concept? An Audio-Diary Study of PBL in Two UK Medical Schools. AMEE 2019, Vienna, Austria, 24-28 Aug 2019. p. 368.

Grant, R., McKernan, M., Meek, S., Huser, C. and Jamieson, S. (2019) Audit of Representation of Protected Characteristics in Learning Materials in a Block of the MBChB. 9th National Scottish Medical Education Conference, Edinburgh, UK, 9-10 May 2019.

Grant, R., Huser, C. , McKernan, M. and Meek, S. (2019) Representation of Protected Characteristics in the Undergraduate Medical Curriculum: a Pilot Audit​. 9th National Scottish Medical Education Conference, Edinburgh, UK, 09-10 May 2019.

Meek, S., Gilbert, K. and Neve, H. (2018) Using the Threshold Concept Framework to Explore Student Learning by PBL in Two UK Medical Schools. ISSOTL18: Toward a Learning Culture, Bergen, Norway, 24-27 Oct 2018.

Marks, L., Meek, S., Huser, C. and Blakemore, L. (2016) Playing the Numbers Game: Students as Assessors in a MOOC Context. 9th Annual University of Glasgow Learning and Teaching Conference, Glasgow, UK, 12 Apr 2016.

Marks, L., Meek, S. and Jackson, M. (2016) Using MOOCs to Increase Exposure to Genomics in an Undergraduate Medical Curriculum. The European Human Genetics Conference 2016, Barcelona, Spain, 21-24 May 2016.

Marks, L., Meek, S. and Jackson, M. (2016) What to do with a MOOC? Using the Latest e-Learning Trend to Enhance Medical Education. HEA Health and Social Care Conference, Glasgow, UK, 24-25 Feb 2016.

Meek, S., Marks, L. and Blakemore, L. (2015) Is Peer Review an Appropriate Assessment and Feedback Tool for a MOOC? AMEE eLearning Symposium, Glasgow, Scotland, 06-09 Sep 2015.

Marks, L., Meek, S., Huser, C. and Blakemore, L. (2014) The Making of a MOOC: Reflections from the Journey! 7th Annual University of Glasgow Learning and Teaching Conference, Glasgow, UK, 10 Apr 2014.

This list was generated on Sat Sep 18 19:19:09 2021 BST.