Professor Andrew Smith

Professor of Clinical Bacteriology (Dental School)

School of Medicine, Dentistry & Nursing, Level 9, 378 Sauchiehall Street, Glasgow Dental Hospital & School, Glasgow, G2 3JZ

Import to contacts

https://orcid.org/0000-0003-0580-4078

Biography

Andrew Smith is Professor of Clinical Bacteriology & Honorary Consultant Microbiologist for NHS Greater Glasgow & Clyde. He is the Director of the Bacterial Respiratory Infections Service, Scottish Microbiology Reference Laboratory (SMiRL), Glasgow Royal Infirmary and Lead Consultant for Oral and Maxillofacial Microbiology, NHS GG&C.

Previously, he has been the Microbiology Consultant Lead for Medical Device Decontamination NHS Glasgow & Clyde (NHS GG&C) for several years sitting on National and International committees. The lead for several National projects, grant funding and peer reviewed publications linked to decontamination in Primary and Secondary Care with the objective of reducing the risk of iatrogenic vCJD. A committee member of the CJD support network.

He is the current President of the Scottish Microbiology Association (http://www.sma.scot.nhs.uk) and Assistant editor of the Journal of Hospital Infection (http://jhiblogger.wordpress.com). Professor Smith is the current chair of the Scottish Antimicrobial Stewardship in Dentistry group (https://www.sapg.scot/about-us/current-projects/)

Research interests

Professor Smith leads a team of scientists and biomedical support workers within the NHS providing service, research and development linked to the following respiratory pathogens such as;

Haemophilus influenzae
Legionella pneumophila
Streptococcus pneumonia
Neisseria meningitidis
Streptococcus pyogenes
Bordetella pertussis

We also have a programme investigating the epidemiology and microbiology of severe odontogenic infections which links to the Dental Scottish Antimicrobial Prescribing Group.

Current research and development programmes

1. Lead PI (with Dr Claire Cameron, HPS) for the Scottish arm of the “Be on the TEAM- teenagers against meningitis” study aims: “Does the MenB vaccine reduce pharyngeal carriage of meningococci?”. Multi-centre UK study. Lead Investigator, Dr Matthew Snape, Oxford Vaccines Group.

2. Introducing real-time Whole Genome Sequencing for the Scottish Bacterial Respiratory Infections Service (excluding TB). Co-ordination of the Reference Laboratory service based on Level 5, New Lister Building, Glasgow Royal Infirmary in collaboration with Health Protection Scotland teams.

Publications

List by: Type | Date

Jump to: 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2001 | 1998

Number of items: 122.

2023

Moen, C. M., Paramjothy, K., Williamson, A., Coleman, H., Lou, X., Smith, A. and Douglas, C. M. (2023) A systematic review of the role of penicillin vs penicillin plus metronidazole in the management of peritonsillar abscess. Journal of Laryngology and Otology, 137(9), pp. 992-996. (doi: 10.1017/S0022215123000804) (PMID:37194922)

Shaw, D. et al. (2023) Trends in invasive bacterial diseases during the first 2 years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries and territories in the IRIS Consortium. Lancet Digital Health, 5(9), e582-e593. (doi: 10.1016/S2589-7500(23)00108-5) (PMID:37516557)

Davies, P. J.B., Russell, C. D., Morgan, A.-R., Taori, S. K., Lindsay, D., Ure, R., Brown, D. and Smith, A. (2023) Increase of severe pulmonary infections in adults caused by M1UK Streptococcus pyogenes, Central Scotland, UK. Emerging Infectious Diseases, 29(8), pp. 1638-1642. (doi: 10.3201/eid2908.230569) (PMID:37343545) (PMCID:PMC10370863)

Smith, A. , Bancroft, R., Ingle, D., Kirk, B., McDonnell, G. and Smith, S. (2023) Misinterpretation of medical device cleaning standards. Journal of Hospital Infection, 135, pp. 199-200. (doi: 10.1016/j.jhin.2023.02.009) (PMID:36889592)

Rodrigues, C.M.C., MacDonald, L., Ure, R., Smith, A. , Cameron, J.C. and Maiden, M.C.J. (2023) Exploiting real-time genomic surveillance data to assess 4CMenB meningococcal vaccine performance in Scotland, 2015 to 2022. mBio, 14(2), e00499-23. (doi: 10.1128/mbio.00499-23) (PMID:37036356) (PMCID:PMC10127610)

Holdstock, V. et al. (2023) National case series of group A streptococcus pleural empyema in children: clinical and microbiological features. Lancet Infectious Diseases, 23(2), pp. 154-156. (doi: 10.1016/S1473-3099(23)00008-7) (PMID:36634683)

Mentzer, A. J. et al. (2023) Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection. Nature Medicine, 29(1), pp. 147-157. (doi: 10.1038/s41591-022-02078-6) (PMID:36228659) (PMCID:PMC9873562)

2022

Carr, J. P. et al. (2022) Impact of meningococcal ACWY conjugate vaccines on pharyngeal carriage in adolescents: evidence for herd protection from the UK MenACWY programme. Clinical Microbiology and Infection, 28(12), 1649.e1-1649.e8. (doi: 10.1016/j.cmi.2022.07.004) (PMID:35840033)

Gorzynski, J., Wee, B., Llano, M., Alves, J., Cameron, R., McMenamin, J., Smith, A. , Lindsay, D. and Fitzgerald, J. R. (2022) Epidemiological analysis of Legionnaires' disease in Scotland: a genomic study. Lancet Microbe, 3(11), e835-e845. (doi: 10.1016/S2666-5247(22)00231-2) (PMID:36240833)

Pagnossin, D., Smith, A. , Oravcova, K. and Weir, W. (2022) Streptococcus canis, the underdog of the genus. Veterinary Microbiology, 273, 109524. (doi: 10.1016/j.vetmic.2022.109524) (PMID:35933975)

Cooper, L., Stankiewicz, N., Sneddon, J., Smith, A. and Seaton, R. A. (2022) Optimum length of treatment with systemic antibiotics in adults with dental infections: a systematic review. Evidence-Based Dentistry, (doi: 10.1038/s41432-022-0801-6) (PMID:36071280) (Early Online Publication)

Cooper, L., Stankiewicz, N., Sneddon, J., Seaton, R. A. and Smith, A. (2022) Indications for the use of metronidazole in the treatment of non-periodontal dental infections: a systematic review. JAC-Antimicrobial Resistance, 4(4), dlac072. (doi: 10.1093/jacamr/dlac072) (PMID:35959239) (PMCID:PMC9361036)

Savulescu, C. et al. (2022) Effectiveness of 10 and 13-valent pneumococcal conjugate vaccines against invasive pneumococcal disease in European children: SpIDnet observational multicentre study. Vaccine, 40(29), pp. 3963-3974. (doi: 10.1016/j.vaccine.2022.05.011) (PMID:35637067)

Cooper, L., Sneddon, J., Thompson, W., Guise, T., Robertson, D. and Smith, A. (2022) Tackling antimicrobial resistance in practice: dental students’ evaluation of university teaching supplemented by an online course. JAC-Antimicrobial Resistance, 4(2), dlac039. (doi: 10.1093/jacamr/dlac039) (PMID:35415610) (PMCID:PMC8994195)

Hanquet, G. et al. (2022) Serotype replacement after introduction of 10-valent and 13-valent pneumococcal conjugate vaccines in 10 countries, Europe. Emerging Infectious Diseases, 28(1), pp. 127-138. (doi: 10.3201/eid2801.210734) (PMID:34932457) (PMCID:PMC8714201)

2021

Wee, B. A. et al. (2021) Population analysis of Legionella pneumophila reveals a basis for resistance to complement-mediated killing. Nature Communications, 12, 7165. (doi: 10.1038/s41467-021-27478-z) (PMID:34887398) (PMCID:PMC8660822)

Swanson, P. A. et al. (2021) AZD1222/ChAdOx1 nCoV-19 vaccination induces a polyfunctional spike protein–specific T H 1 response with a diverse TCR repertoire. Science Translational Medicine, 13(620), eabj7211. (doi: 10.1126/scitranslmed.abj7211) (PMID:34591596)

Hillson, K., Clemens, S. C., Madhi, S. A., Voysey, M., Pollard, A. J., Minassian, A. M. and Oxford COVID Vaccine Trial Group, . (2021) Fertility rates and birth outcomes after ChAdOx1 nCoV-19 (AZD1222) vaccination. Lancet, 398(10312), pp. 1683-1684. (doi: 10.1016/S0140-6736(21)02282-0) (PMID:34688353) (PMCID:PMC8530465)

Robertson, D. and Smith, A. J. (2021) Significant increase in hospital admissions for the management of severe dental infection in England 2000-2020. Journal of Infection, 83(4), pp. 499-501. (doi: 10.1016/j.jinf.2021.07.009) (PMID:34289400)

Smith, A.J. (2021) The devil is in the validation and design; managing the risk from opportunistic pathogens in the dental unit. Journal of Hospital Infection, 114, pp. 61-62. (doi: 10.1016/j.jhin.2021.05.013) (PMID:34087260)

Freudenhammer, M. et al. (2021) Invasive Group B Streptococcus disease with recurrence and in multiples: Towards a better understanding of GBS late-onset sepsis. Frontiers in Immunology, 12, 617925. (doi: 10.3389/fimmu.2021.617925) (PMID:34149682) (PMCID:PMC8208644)

Brueggemann, A. B. et al. (2021) Changes in the incidence of invasive disease due to Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis during the COVID-19 pandemic in 26 countries and territories in the Invasive Respiratory Infection Surveillance Initiative: a prospective analysis of surveillance data. Lancet Digital Health, 3(6), e360-e370. (doi: 10.1016/S2589-7500(21)00077-7) (PMID:34045002) (PMCID:PMC8166576)

Collin, S. M. et al. (2021) Uncovering infant group B streptococcal (GBS) disease clusters in the UK and Ireland through genomic analysis: a population-based epidemiological study. Clinical Infectious Diseases, 72(9), e296-e302. (doi: 10.1093/cid/ciaa1087) (PMID:32766850)

MacLennan, J. M. et al. (2021) Meningococcal carriage in periods of high and low invasive meningococcal disease incidence in the United Kingdom – a cross-sectional, observational survey. Lancet Infectious Diseases, 21(5), pp. 677-687. (doi: 10.1016/S1473-3099(20)30842-2) (PMID:33482143)

Emary, K. R. W. et al. (2021) Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial. Lancet, 397(10282), pp. 1351-1362. (doi: 10.1016/S0140-6736(21)00628-0) (PMID:33798499) (PMCID:PMC8009612)

Pagnossin, D., Smith, A. , Weir, W. , Crestani, C., Lindsay, D., Ure, R. and Oravcova, K. (2021) Complete genome sequences of three invasive strains of Streptococcus pyogenes subtype emm5.23 isolated in Scotland. Microbiology Resource Announcements, 10(15), e00101-21. (doi: 10.1128/MRA.00101-21) (PMID:33858921) (PMCID:PMC8050963)

Voysey, M. et al. (2021) Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials. Lancet, 397(10277), pp. 881-891. (doi: 10.1016/S0140-6736(21)00432-3) (PMID:33617777) (PMCID:PMC7894131)

Voysey, M. et al. (2021) Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. Lancet, 397(10269), pp. 99-111. (doi: 10.1016/S0140-6736(20)32661-1) (PMID:33306989) (PMCID:PMC7723445)

Rodrigues, C. M.C., Jolley, K. A., Smith, A. , Cameron, J. C., Feavers, I. M. and Maiden, M. C.J. (2021) Meningococcal Deduced Vaccine Antigen Reactivity (MenDeVAR) Index: a rapid and accessible tool that exploits genomic data in public health and clinical microbiology applications. Journal of Clinical Microbiology, 59(1), e02161-20. (doi: 10.1128/JCM.02161-20) (PMID:33055180)

Flaxman, A. et al. (2021) Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002). Lancet, 398(10304), pp. 981-990. (doi: 10.1016/S0140-6736(21)01699-8) (PMID:34480858) (PMCID:PMC8409975)

Garcia Quesada, M. et al. (2021) Serotype distribution of remaining pneumococcal meningitis in the mature PCV10/13 period: findings from the PSERENADE project. Microorganisms, 9(4), 738. (doi: 10.3390/microorganisms9040738) (PMID:33916227) (PMCID:PMC8066874)

2020

Lucidarme, J. et al. (2020) Genomic analysis of the Meningococcal ST-4821 complex – western clade, potential sexual transmission and predicted antibiotic susceptibility and vaccine coverage. PLoS ONE, 15(12), e0243426. (doi: 10.1371/journal.pone.0243426) (PMID:33301524) (PMCID:PMC7728179)

Persoon, I. F., Stankiewicz, N., Smith, A. , de Soet, H. (J.J.) and Volgenant, C. M.C. (2020) A review of respiratory protection measures recommended in Europe for dental procedures during the COVID-19 pandemic. Journal of Hospital Infection, 106(2), pp. 330-331. (doi: 10.1016/j.jhin.2020.07.027)

Smith, A.J. , Palmer, N.O.A., Seaton, R.A. and Ternhag, A. (2020) Letter to the Editor: “Risk of adverse reactions to oral antibiotics prescribed by dentists". Journal of Dental Research, 99(7), p. 863. (doi: 10.1177/0022034520917143) (PMID:32282275)

Smith, A. , Al-Mahdi, R., Malcolm, W., Palmer, N., Dahlen, G. and Al-Haroni, M. (2020) Comparison of antimicrobial prescribing for dental and oral infections in England and Scotland with Norway and Sweden and their relative contribution to national consumption 2010–2016. BMC Oral Health, 20, 172. (doi: 10.1186/s12903-020-01163-x) (PMID:32546149) (PMCID:PMC7298788)

Musser, J. M. et al. (2020) Reduced in vitro susceptibility of Streptococcus pyogenes to beta-lactam antibiotics associated with mutations in the pbp2x gene is geographically widespread. Journal of Clinical Microbiology, 58(4), e01993-19. (doi: 10.1128/JCM.01993-19) (PMID:31996443)

2019

Bratcher, H. B. et al. (2019) UKMenCar4: a cross-sectional survey of asymptomatic meningococcal carriage amongst UK adolescents at a period of low invasive meningococcal disease incidence. Wellcome Open Research, 4, 118. (doi: 10.12688/wellcomeopenres.15362.2) (PMID:31544158) (PMCID:PMC6749934)

Hanquet, G. et al. (2019) Effect of childhood pneumococcal conjugate vaccination on invasive disease in older adults of 10 European countries: implications for adult vaccination. Thorax, 74(5), pp. 473-482. (doi: 10.1136/thoraxjnl-2018-211767) (PMID:30355641) (PMCID:PMC6484683)

O'Sullivan, C. P. et al. (2019) Group B streptococcal disease in UK and Irish infants younger than 90 days, 2014–15: a prospective surveillance study. Lancet Infectious Diseases, 19(1), pp. 83-90. (doi: 10.1016/S1473-3099(18)30555-3) (PMID:30497953)

2018

Smith, A. , Winter, S., Lappin, D., Sherriff, A. , McIvor, I., Philp, P., Suttner, N., Holmes, S. and Stewart, A. (2018) Reducing the risk of iatrogenic Creutzfeldt–Jakob disease by improving the cleaning of neurosurgical instruments. Journal of Hospital Infection, 100(3), e70-e76. (doi: 10.1016/j.jhin.2018.03.001) (PMID:29530742)

Winter, S., McDonagh, G., Lappin, D. and Smith, A.J. (2018) Assessing the efficacy and cost of detergents used in a primary care automated washer disinfector. British Dental Journal, 225, pp. 315-319. (doi: 10.1038/sj.bdj.2018.643) (PMID:30141495)

Brooks, D., Polubothu, P., Young, D., Booth, M.G. and Smith, A. (2018) Sepsis caused by bloodstream infection in patients in the intensive care unit: the impact of inactive empiric antimicrobial therapy on outcome. Journal of Hospital Infection, 98(4), pp. 369-374. (doi: 10.1016/j.jhin.2017.09.031) (PMID:28993134)

Rodrigues, C. M.C., Lucidarme, J., Borrow, R., Smith, A. , Cameron, J. C., Moxon, E. R. and Maiden, M. C.J. (2018) Genomic surveillance of 4CMenB vaccine antigenic variants among disease-causing Neisseria meningitidis isolates, United Kingdom, 2010–2016. Emerging Infectious Diseases, 24(4), pp. 673-682. (doi: 10.3201/eid2404.171480) (PMID:29553330) (PMCID:PMC5875271)

Smith, A. (2018) Metronidazole resistance: a hidden epidemic? British Dental Journal, 224(6), pp. 403-404. (doi: 10.1038/sj.bdj.2018.221) (PMID:29545544)

2017

Beres, S. B., Olsen, R. J., Saavedra, M. O., Ure, R., Reynolds, A., Lindsay, D. S.J., Smith, A. J. and Musser, J. M. (2017) Genome sequence analysis of emm89 Streptococcus pyogenes strains causing infections in Scotland, 2010–2016. Journal of Medical Microbiology, 66(12), pp. 1765-1773. (doi: 10.1099/jmm.0.000622) (PMID:29099690)

Winter, S., Smith, A. , Lappin, D., McDonagh, G. and Kirk, B. (2017) Failure of non-vacuum steam sterilization processes for dental handpieces. Journal of Hospital Infection, 97(4), pp. 343-347. (doi: 10.1016/j.jhin.2017.09.004)

Winter, S., Smith, A. , Lappin, D., McDonagh, G. and Kirk, B. (2017) Investigating steam penetration using thermometric methods in dental handpieces with narrow internal lumens during sterilizing processes with non-vacuum or vacuum processes. Journal of Hospital Infection, 97(4), pp. 338-342. (doi: 10.1016/j.jhin.2017.07.033) (PMID:28778810)

Winter, S., Smith, A. , Kirk, B. and Lappin, D. (2017) The influence of lubricating oil on the efficacy of steam sterilization processes used to decontaminate dental handpieces = Die Auswirkung von Pflegeöl auf die Wirksamkeit der Dampfsterilisation zur Dekontamination zahnärztlicher Handstücke. Hygiene and Medizin, 42(12), D149-D154.

Slotved, H.-C. et al. (2017) External quality assurance for laboratory identification and capsular typing of Streptococcus pneumoniae. Scientific Reports, 7, 13280. (doi: 10.1038/s41598-017-13605-8) (PMID:29038446) (PMCID:PMC5643306)

Savulescu, C. et al. (2017) Effect of high-valency pneumococcal conjugate vaccines on invasive pneumococcal disease in children in SpIDnet countries: an observational multicentre study. Lancet Respiratory Medicine, 5(8), pp. 648-656. (doi: 10.1016/S2213-2600(17)30110-8) (PMID:28359798)

Robertson, P., Smith, A. , Anderson, M., Stewart, J., Hamilton, K., McNamee, S. and Curran, E. T. (2017) Transmission of Salmonella enteritidis after endoscopic retrograde cholangiopancreatography because of inadequate endoscope decontamination. American Journal of Infection Control, 45(4), pp. 440-442. (doi: 10.1016/j.ajic.2016.11.024) (PMID:28063730)

Winter, S., Smith, A. , Kirk, B. and Lappin, D. (2017) The influence of lubricating oil on the efficacy of steam sterilization processes used to decontaminate dental handpieces. Zentralsterilisation = Central Services, 25(1), pp. 31-35.

2016

Lucidarme, J. et al. (2016) An international invasive meningococcal disease outbreak due to a novel and rapidly expanding serogroup W strain, Scotland and Sweden, July to August 2015. Eurosurveillance, 21(45), 30395. (doi: 10.2807/1560-7917.ES.2016.21.45.30395)

Smith-Palmer, A. et al. (2016) Outbreak of Neisseria meningitidis capsular group W among scouts returning from the World Scout Jamboree, Japan, 2015. Eurosurveillance, 21(45), 30392. (doi: 10.2807/1560-7917.ES.2016.21.45.30392)

Brooks, D., Smith, A. , Young, D., Fulton, R. and Booth, M. G. (2016) Mortality in intensive care: The impact of bacteremia and the utility of systemic inflammatory response syndrome. American Journal of Infection Control, 44(11), pp. 1291-1295. (doi: 10.1016/j.ajic.2016.04.214) (PMID:27339793)

Lima, C. M. A., Smith, A. J. , Fonseca Silva, A. S., Flório, F. M. and Zanin, L. (2016) Infection prevention and control in dental surgeries in the Pará state prison system in Brazil. American Journal of Infection Control, 44(11), pp. 1417-1418. (doi: 10.1016/j.ajic.2016.04.213) (PMID:27320900)

Lindsay, D. S.J., Brown, A. W., Scott, K. J., Denham, B., Thom, L., Rundell, G., Ure, R., Jones, B. and Smith, A. J. (2016) Circulating emm types of Streptococcus pyogenes in Scotland: 2011-2015. Journal of Medical Microbiology, 65(10), pp. 1229-1231. (doi: 10.1099/jmm.0.000335)

Brehony, C., Rodrigues, C. M.C., Borrow, R., Smith, A. , Cunney, R., Moxon, E. R. and Maiden, M. C.J. (2016) Distribution of Bexsero® Antigen Sequence Types (BASTs) in invasive meningococcal disease isolates: Implications for immunisation. Vaccine, 34(39), pp. 4690-4697. (doi: 10.1016/j.vaccine.2016.08.015) (PMID:27521232) (PMCID:PMC5012890)

Roy, K.M., Ahmed, S., Inkster, T., Smith, A. and Penrice, G. (2016) Managing the risk of viral haemorrhagic fever transmission in a non-high-level intensive care unit: experiences from a case of Crimean-Congo haemorrhagic fever in Scotland. Journal of Hospital Infection, 93(3), pp. 304-308. (doi: 10.1016/j.jhin.2016.02.023) (PMID:27174232)

Kirk, B., Smith, A. and Winter, S. (2016) Performance of Hollow Load Process Challenge Devices (HLPCDs) for the determination of air removal and steam penetration in porous load steam sterilization processes: Part 1 – The evolution of HLPCDs in standards and a review of the current supporting published evidence. Zentralsterilisation = Central Services, 24(5), pp. 308-314.

Kirk, B., Smith, A. and Winter, S. (2016) Performance of Hollow Load Process Challenge Devices (HLPCDs) for the determination of air removal and steam penetration in porous load steam sterilization processes: Part 2 - An evaluation of a number commercially produced HLPCDs. Zentralsterilisation = Central Services, 24(6), pp. 380-387.

2015

Deshpande, A., Smith, G.W.G. and Smith, A.J. (2015) Biofouling of surgical power tools during routine use. Journal of Hospital Infection, 90(3), pp. 179-185. (doi: 10.1016/j.jhin.2015.03.006) (PMID:25922337)

Robertson, P. et al. (2015) Risk-assessment-based approach to patients exposed to endoscopes contaminated with Pseudomonas spp. Journal of Hospital Infection, 90(1), pp. 66-69. (doi: 10.1016/j.jhin.2014.12.012) (PMID:25676110)

Hanratty, J., Changez, H., Smith, A. and Wales, C. (2015) Panton-valentine leukocidin positive staphylococcal aureus infections of the head and neck: case series and brief review of literature. Journal of Oral and Maxillofacial Surgery, 73(4), pp. 666-670. (doi: 10.1016/j.joms.2014.10.004) (PMID:25544295)

Robertson, D. P. , Keys, W., Rautemaa-Richardson, R. and Smith, A. J. (2015) Management of severe acute dental infections. British Medical Journal, 350, h1300. (doi: 10.1136/bmj.h1300) (PMID:25804417)

McCormack, M.G., Smith, A.J. , Akram, A.N., Jackson, M., Robertson, D. and Edwards, G. (2015) Staphylococcus aureus and the oral cavity: An overlooked source of carriage and infection? American Journal of Infection Control, 43(1), pp. 35-37. (doi: 10.1016/j.ajic.2014.09.015) (PMID:25564121)

2014

Khalsa, K., Smith, A. , Morrison, P., Shaw, D., Peat, M., Howard, P., Hamilton, K. and Stewart, A. (2014) Contamination of a purified water system by Aspergillus fumigatus in a new endoscopy reprocessing unit. American Journal of Infection Control, 42(12), pp. 1337-1339. (doi: 10.1016/j.ajic.2014.08.008)

Marek, A. et al. (2014) Endoscopy supply water and final rinse testing: five years of experience. Journal of Hospital Infection, 88(4), pp. 207-212. (doi: 10.1016/j.jhin.2014.09.004)

McDonagh, G. and Smith, A. J. (2014) Absence of practical skills addressed. Health Estate Journal, 68(8), pp. 23-28. (PMID:25282982)

Smith, G. and Smith, A. (2014) Microbial contamination of used dental handpieces. American Journal of Infection Control, 42(9), pp. 1019-1021. (doi: 10.1016/j.ajic.2014.06.008)

Lamb, K. E. et al. (2014) Trends in serotypes and sequence types among cases of invasive pneumococcal disease in Scotland, 1999–2010. Vaccine, 32(34), pp. 4356-4363. (doi: 10.1016/j.vaccine.2013.05.079)

Smith, A. , Smith, G., Lappin, D.F., Baxter, H.C., Jones, A. and Baxter, R.L. (2014) Dental handpiece contamination: a proteomics and surface analysis approach. Biofouling, 30(1), pp. 29-39. (doi: 10.1080/08927014.2013.839782)

2013

Smith, A. , Johnston, C., Inverarity, D., Slack, M., Diggle, M. and Mitchell, T. (2013) Investigating the role of pneumococcal neuraminidase A activity in isolates from pneumococcal haemolytic uraemic syndrome. Journal of Medical Microbiology, 62(11), pp. 1735-1742. (doi: 10.1099/jmm.0.063479-0)

Smith, A.J. (2013) Decontamination technology assessments – who assesses the assessments? British Dental Journal, 215(2), pp. 65-67. (doi: 10.1038/sj.bdj.2013.681)

2012

Smith, G.W.G., McNeil, J., Ramage, G. and Smith, A.J. (2012) In vitro evaluation of cleaning efficacy of detergents recommended for use on dental instruments. American Journal of Infection Control, 40(9), e255-e259. (doi: 10.1016/j.ajic.2012.05.009)

Teles, C., Smith, A. and Lang, S. (2012) Antibiotic modulation of the plasminogen binding ability of viridans group streptococci. Antimicrobial Agents and Chemotherapy, 56(1), pp. 458-463. (doi: 10.1128/AAC.00452-11)

de Pedro Cuesta, J. et al. (2012) Sensitivity to biases of case-control studies on medical procedures, particularly surgery and blood transfusion, and risk of Creutzfeldt-Jakob disease. Neuroepidemiology, 39(1), pp. 1-18. (doi: 10.1159/000339318)

Kirby, E. et al. (2012) Bioassay studies support the potential for iatrogenic transmission of variant Creutzfeldt Jakob Disease through dental procedures. PLoS ONE, 7(11), e49850. (doi: 10.1371/journal.pone.0049850) (PMID:23226225) (PMCID:PMC3511499)

Molesworth, A.M., Smith, A.J. , Everington, D., Ord, F., Watt, P., Will, R.G. and Ward, H.J.T. (2012) Risk factors for variant Creutzfeldt-Jakob disease in dental practice: a case-control study. British Dental Journal, 213(11), E19. (doi: 10.1038/sj.bdj.2012.1089)

2011

Vassey, M. et al. (2011) A quantitative assessment of residual protein levels on dental instruments reprocessed by manual, ultrasonic and automated cleaning methods. British Dental Journal, 210(9), E14. (doi: 10.1038/sj.bdj.2011.144)

Mabbott, F.A., Mullen, A.B., Smith, A. , Smith, G.L. and Boyter, A.C. (2011) Qualitative analysis of microbial contamination of inhalers. Journal of Hospital Infection, 77(3), pp. 277-278. (doi: 10.1016/j.jhin.2010.11.005)

Smith, G.W.G., Goldie, F., Long, S., Lappin, D.F., Ramage, G. and Smith, A.J. (2011) Quantitative analysis of residual protein contamination of podiatry instruments reprocessed through local and central decontamination units. Journal of Foot and Ankle Research, 4(2), (doi: 10.1186/1757-1146-4-2)

Teles, C., Smith, A. , Ramage, G. and Lang, S. (2011) Identification of clinically relevant viridans group streptococci by phenotypic and genotypic analysis. European Journal of Clinical Microbiology and Infectious Diseases, 30(2), pp. 243-250. (doi: 10.1007/s10096-010-1076-y)

Teles, C., Smith, A. , Ramage, G. and Lang, S. (2011) The role of streptococcal plasmin(ogen) binding in infective endocarditis. European Journal of Clinical Microbiology and Infectious Diseases, 30(1), pp. 127-129. (doi: 10.1007/s10096-010-1053-5)

2010

Cooper, P.R., Takahashi, Y., Graham, L.W., Simon, S., Imazato, S. and Smith, A.J. (2010) Inflammation–regeneration interplay in the dentine–pulp complex. Journal of Dentistry, 38(9), pp. 687-697. (doi: 10.1016/j.jdent.2010.05.016)

Johnston, C., Hinds, J., Smith, A. , van der Linden, M., Van Eldere, J. and Mitchell, T.J. (2010) Detection of large numbers of pneumococcal virulence genes in Streptococci of the Mitis group. Journal of Clinical Microbiology, 48(8), pp. 2762-2769. (doi: 10.1128/JCM.01746-09)

Jefferies, J.M., Smith, A.J., Edwards, G.F.S., McMenamin, J., Mitchell, T.J. and Clarke, S.C. (2010) Temporal analysis of invasive pneumococcal clones from Scotland illustrates fluctuations in diversity of serotype and genotype in the absence of pneumococcal conjugate vaccine. Journal of Clinical Microbiology, 48(1), pp. 87-96. (doi: 10.1128/JCM.01485-09)

Cooke, B. et al. (2010) Antibiotic resistance in invasive Streptococcus pneumoniae isolates identified in Scotland between 1999 and 2007. Journal of Medical Microbiology, 59(10), p. 1212. (doi: 10.1099/jmm.0.022954-0)

Jefferies, J. M. C., Tocheva, A. S., Rubery, H., Bennett, J., Garland, J., Christodoulides, M., Faust, S. N., Smith, A. , Mitchell, T.J. and Clarke, S. C. (2010) Identification of novel pneumolysin alleles from paediatric carriage isolates of Streptococcus pneumoniae. Journal of Medical Microbiology, 59(7), pp. 808-814. (doi: 10.1099/jmm.0.018663-0)

Smith, A. , Lockhart, D.E.A., Tyers, A. and Poxton, I.R. (2010) A survey of the identification and susceptibility testing of anaerobes in diagnostic microbiology laboratories in Scotland, UK. Journal of Antimicrobial Chemotherapy, 65(4), p. 805. (doi: 10.1093/jac/dkq010)

Smith, A.J. , Lockhart, D.E.A., McDonald, E., Creanor, S., Hurrell, D. and Bagg, J. (2010) Design of dental surgeries in relation to instrument decontamination. Journal of Hospital Infection, 76(4), pp. 340-344. (doi: 10.1016/j.jhin.2010.06.002)

2009

Smith, A. .J. , Creanor, S. and Hurrell, D. J. (2009) Survey of instrument decontamination in dental surgeries located in Scottish prisons. American Journal of Infection Control, 37(8), pp. 689-690. (doi: 10.1016/j.ajic.2009.04.282)

Smith, A., Creanor, S., Hurrell, D., Bagg, J. and McCowan, M. (2009) Management of infection control in dental practice. Journal of Hospital Infection, 71(4), pp. 353-358. (doi: 10.1016/j.jhin.2008.11.026)

Edwards, G.F., Johnstone, L., Paterson, G., McIntyre, J., McHugh, S., Smith, A. and Smith, A.J. (2009) Hand hygiene undertaken by students and staff in a dental teaching hospital. Journal of Hospital Infection, 71(2), pp. 188-189.

Lockhart, D., Chapman, K., Hurrell, D., Smith, A. and Smith, A. (2009) Evaluation of a course on the operation and management of a local decontamination unit for undergraduate dental students. British Dental Journal, 207(6), pp. 285-289.

Lockhart, D., Smith, A. and Smith, A. (2009) An evaluation of a pilot study of a web-based educational initiative for educating and training undergraduate dental students in infection prevention. British Dental Journal, 207(5), pp. 223-226.

Pye, A., Lockhart, D., Dawson, M., Murray, C., Smith, A. and Smith, A. (2009) A review of dental implants and infection. Journal of Hospital Infection, 72(2), pp. 104-110.

Robertson, D. and Smith, A.J. (2009) The microbiology of the acute dental abscess. Journal of Medical Microbiology, 58(2), pp. 155-162. (doi: 10.1099/jmm.0.003517-0)

Smith, A., Smith, A., Creanor, S. and Hurrell, D. (2009) Survey of instrument decontamination in dental surgeries located in Scottish prisons. American Journal of Infection Control, 37(8), pp. 689-690.

Smith, G. W. G., Smith, A. J. , Creanor, S., Hurrell, D., Bagg, J. and Lappin, D. F. (2009) Survey of the decontamination and maintenance of dental handpieces in general dental practice. British Dental Journal, 207(4), E7. (doi: 10.1038/sj.bdj.2009.761)

Smith, G., Smith, A. , Creanor, S., Hurrell, D., Bagg, J. and Lappin, D. (2009) Summary of: Survey of the decontamination and maintenance of dental handpieces in general dental practice. British Dental Journal, 207(4), pp. 160-161. (doi: 10.1038/sj.bdj.2009.742)

2008

Lockhart, D., Smith, A. and Smith, A. (2008) At the sharp end of general dental practice. British Dental Journal, pp. 40-43.

Roebuck, E., Strang, R., Green, I., Smith, A., Smith, A. and Walker, J. (2008) The availability and content of dental instrument manufacturers' decontamination information. British Dental Journal, 204(8),

2007

Bagg, J., Henry, M., Hurrell, D., Mathewson, H., McHugh, S. and Smith, A. (2007) A method for surveying instrument decontamination procedures in general dental practice. British Dental Journal, 202, (doi: 10.1038/bdj.2007.125)

Bagg, J., Hurrell, D., Irvine, G., McHugh, S. and Smith, A. (2007) Pre-sterilisation cleaning of re-usable instruments in general dental practice. British Dental Journal, 202, (doi: 10.1038/bdj.2007.124)

Bagg, J., Hurrell, D., McHugh, S. and Smith, A. (2007) Sterilisation of re-usable instruments in general dental practice. British Dental Journal, 203, (doi: 10.1038/bdj.2007.912)

Jefferies, J., Nieminen, L., Kirkham, L., Johnston, C., Smith, A. and Mitchell, T. (2007) Identification of a secreted cholesterol-dependent cytolysin (Mitilysin) from Streptococcus mitis. Journal of Bacteriology, 189, pp. 627-632. (doi: 10.1128/JB.01092-06)

Jefferies, J. et al. (2007) Presence of nonhemolytic pneumolysin in serotypes of Streptococcus pneumoniae associated with disease outbreaks. Journal of Infectious Diseases, 196, pp. 936-944. (doi: 10.1086/520091)

2006

Bryan, R., Hosey, M., Muir, M., Smith, A. and Wright, G. (2006) Dental follicle infection following a dog bite. International Journal of Paediatric Dentistry, 16, pp. 147-150.

Clarke, S., Edwards, G., Jefferies, J., McMenamin, J., Mitchell, T. and Smith, A. (2006) Pneumococci causing invasive disease in children prior to the introduction of pneumococcal conjugate vaccine in Scotland. Journal of Medical Microbiology, 55, pp. 1079-1084. (doi: 10.1099/jmm.0.46550-0)

Smith, A.J., Jefferies, J., Clarke, S.C., Dowson, C., Edwards, G.F.S. and Mitchel, T.J. (2006) Distribution of epidemic anti biotic-resistant pneumococcal clones in Scottish pneumococcal isolates analysed by multilocus sequence typing. Microbiology: SGM, 152, pp. 361-365. (doi: 10.1099/mic.0.28419-0)

2005

Fry, N. K., Duncan, J., Malnick, H., Warner, M., Smith, A. , Jackson, M. S. and Ayoub, A. (2005) Bordetella petrii clinical isolate. Emerging Infectious Diseases, 11(7), pp. 1131-1133. (doi: 10.3201/eid1107.050046) (PMID:16022798) (PMCID:PMC3371814)

Letters, S., Smith, A., McHugh, E. and Bagg, J. (2005) A study of visual and blood contamination on reprocessed endodontic files from general dental practice. British Dental Journal, 199, pp. 522-525. (doi: 10.1038/sj.bdj.4812811)

Smith, A., Patterson, C., Yarnell, J., Rumley, A., Ben Shlomo, Y. and Lowe, G. (2005) Which hemostatic markers add to the predictive value of conventional risk factors for coronary heart disease and ischemic stroke? The Caerphilly Study. Circulation, 112, pp. 3080-3087. (doi: 10.1161/CIRCULATIONAHA.105.557132)

Smith, A., Hall, V., Thakker, B. and Gemmell, C. (2005) Antimicrobial susceptibility testing of Actinomyces species with 12 antimicrobial agents. Journal of Antimicrobial Chemotherapy, 56, pp. 407-409. (doi: 10.1093/jac/dki206)

Smith, A., Letters, S., Lange, A., Perrett, D., McHugh, E. and Bagg, J. (2005) Residual protein levels on reprocessed dental instruments. Journal of Hospital Infection, 61, pp. 237-241. (doi: 10.1016/j.jhin.2005.01.021)

2004

Jefferies, J., Smith, A., Clarke, S., Dowson, C. and Mitchell, T. (2004) Genetic analysis of diverse disease-causing pneumococci indicates high levels of diversity within serotypes and capsule switching. Journal of Clinical Microbiology, 42, pp. 5681-5688. (doi: 10.1128/JCM.42.12.5681-5688.2004)

2003

Al, D., Morrison, D., Robertson, D., Smith, A. and Tang, M. (2003) Efficacy of oral hygiene products against MRSA and MSSA isolates. Journal of Antimicrobial Chemotherapy, 52(4), pp. 738-739.

Goodall, C., Leitch, J. and Smith, A. (2003) Antibiotic use among children attending for outpatient general anesthesia for dental extractions. Journal of Dental Research, 82, B107-B107.

Smith, A.J. , Morrison, D., Roberston, D., Tang, M.K. and Al-Doori, Z. (2003) Efficacy of oral hygine products against MRSA and MSSA isolates. Journal of Antimicrobial Chemotherapy, 52(4), 738 -739. (doi: 10.1093/jac/dkg394)

2001

Smith, A.J. , Cameron, S.O., Bagg, J. and Kennedy, D. (2001) Management of needlestick injuries in general dental practice. British Dental Journal, 190(12), pp. 645-650. (doi: 10.1038/sj.bdj.4801064)

1998

Smith, A.J. , Alexander, M., Mackenzie, D., Lennon, A., Riggio, M.P. and MacFarlane, T.W. (1998) Microbial factors and gingival crevicular fluid aspartate aminotransferase levels: a cross-sectional study. Journal of Clinical Periodontology, 25(4), pp. 334-339. (doi: 10.1111/j.1600-051X.1998.tb02450.x)

This list was generated on Fri Apr 19 15:31:14 2024 BST.

Jump to: Articles

Number of items: 122.

Articles

Pagnossin, D., Smith, A. , Oravcova, K. and Weir, W. (2022) Streptococcus canis, the underdog of the genus. Veterinary Microbiology, 273, 109524. (doi: 10.1016/j.vetmic.2022.109524) (PMID:35933975)

Smith, A. (2018) Metronidazole resistance: a hidden epidemic? British Dental Journal, 224(6), pp. 403-404. (doi: 10.1038/sj.bdj.2018.221) (PMID:29545544)

Kirk, B., Smith, A. and Winter, S. (2016) Performance of Hollow Load Process Challenge Devices (HLPCDs) for the determination of air removal and steam penetration in porous load steam sterilization processes: Part 2 - An evaluation of a number commercially produced HLPCDs. Zentralsterilisation = Central Services, 24(6), pp. 380-387.

Marek, A. et al. (2014) Endoscopy supply water and final rinse testing: five years of experience. Journal of Hospital Infection, 88(4), pp. 207-212. (doi: 10.1016/j.jhin.2014.09.004)

McDonagh, G. and Smith, A. J. (2014) Absence of practical skills addressed. Health Estate Journal, 68(8), pp. 23-28. (PMID:25282982)

Smith, G. and Smith, A. (2014) Microbial contamination of used dental handpieces. American Journal of Infection Control, 42(9), pp. 1019-1021. (doi: 10.1016/j.ajic.2014.06.008)

Smith, A.J. (2013) Decontamination technology assessments – who assesses the assessments? British Dental Journal, 215(2), pp. 65-67. (doi: 10.1038/sj.bdj.2013.681)

Pye, A., Lockhart, D., Dawson, M., Murray, C., Smith, A. and Smith, A. (2009) A review of dental implants and infection. Journal of Hospital Infection, 72(2), pp. 104-110.

Robertson, D. and Smith, A.J. (2009) The microbiology of the acute dental abscess. Journal of Medical Microbiology, 58(2), pp. 155-162. (doi: 10.1099/jmm.0.003517-0)

Lockhart, D., Smith, A. and Smith, A. (2008) At the sharp end of general dental practice. British Dental Journal, pp. 40-43.

Bagg, J., Hurrell, D., McHugh, S. and Smith, A. (2007) Sterilisation of re-usable instruments in general dental practice. British Dental Journal, 203, (doi: 10.1038/bdj.2007.912)

Bryan, R., Hosey, M., Muir, M., Smith, A. and Wright, G. (2006) Dental follicle infection following a dog bite. International Journal of Paediatric Dentistry, 16, pp. 147-150.

Al, D., Morrison, D., Robertson, D., Smith, A. and Tang, M. (2003) Efficacy of oral hygiene products against MRSA and MSSA isolates. Journal of Antimicrobial Chemotherapy, 52(4), pp. 738-739.

Goodall, C., Leitch, J. and Smith, A. (2003) Antibiotic use among children attending for outpatient general anesthesia for dental extractions. Journal of Dental Research, 82, B107-B107.

This list was generated on Fri Apr 19 15:31:14 2024 BST.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

Genomic investigation into Legionnaires' disease in Scotland
Chief Scientist Office
2016 - 2017
Ozone destruction of biofilms for high level decontamination in healthcare
Innovate UK
2015 - 2016
Reducing the risk of vCJD by improving the cleanability of neurosurgical instruments
Scottish Government
2014 - 2015
Investigating Dental Treatment as a Possible Risk Factor for CJD
Department of Health
2008 - 2010
Assessing the feasibility of accessing dental case records for detailed past dental histories in CJD cases and controls
Department of Health
2005 - 2006
Examination of the potential for transmission of variant CJD through dentistry
Health Protection Agency
2004 - 2010

Supervision

PhD students

1. Title: “Population genomic identification of bacterial traits linked to the outcome of Legionnaires’ disease”. Co-supervisor with Prof Ross Fitzgerald & Dr Brian Wee (University of Edinburgh, Primary Supervisor). MRC funded Doctoral Training Programme (DTP) in Precision Medicine. Student: Jamie Gorzynski @ed.ac.uk (commenced September 2018).

2. Title: “Molecular Epidemiology of virulence genes in Streptococcal species causing skin and soft tissue infection in man and animals”. Glasgow University PhD training programme. Co-supervisors Dr Kataina Oracova and Dr Willie Weir, Veterinary School, University of Glasgow. Student: Davide Pagnossin (commenced November 2019).

Masters students

The team regularly supervises Masters level projects for example,

a. “PCR for the fHbp gene in meningococcal culture negative specimens to determine coverage by the Bexsero fHbp vaccine antigen”. Student: Patrycja Szalczyk. Lab supervisor: Roisin Ure.

b. “Assessing the feasibility of replacing phenotypic AST with WGS informatics at the Scottish Meningococcal reference laboratory”. Student: Dr Michael Murphy. Co-supervisors: Rosin Ure & Odile Harrison (University of Oxford)

a. Genomic epidemiology of Legionnaires Disease in Scotland: towards effective outbreak investigation. Chief Scientist Office, Scotland.

b. Improving understanding and outcomes: Linking genomic, clinical and epidemiological data for meningococcal disease in Scotland. Meningitis Research Foundation.

Teaching

We have one of the best courses Internationally for teaching undergraduates decontamination sciences and infection prevention and control (IP&C) with a unique and dedicated teaching laboratory suite. Professor Smith is the only Clinical Microbiologist to have passed the UK Advanced Course in Sterilization Technology (ACIST). The teaching is based on our previous research programmes on medical device decontamination which has been widely published and quoted, for example, work by a prior departmental PhD student Dr Sandra Winter has demonstrated that a frequently used steam sterilizer in general dental practice fails to sterilise dental handpieces (Winter S, et al Failure of non-vacuum steam sterilization processes for dental handpieces. Journal of Hospital Infection 2017: 97(4): 343-347). We use this evidence based approach to underpin our teaching curriculum which is led and delivered by;

Lynne Cotter (Infection Prevention and Control)

And

Stuart Smith (Decontamination Sciences)

Dr AJ Smith

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Professor Andrew Smith

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