Dr Mark Bailey

  • Senior Lecturer (Life Sciences Biomolecular Sciences)
  • Associate (Institute of Molecular Cell & Systems Biology)

Research interests

Research Interests

Human genetics and molecular genetics: mapping and identification of disease genes in Mendelian and complex disorders; molecular pathology and gene therapy of human genetic disorders; Rett syndrome; Psychiatric disorders and psychological traits; Type 2 diabetes/obesity/body composition/performance; Ménière disease; gene family evolution; meme-gene co-evolution; evolution of the human brain.


Further information about our current research can be viewed here.


Publications

List by: Type | Date

Jump to: 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2007 | 2006 | 2005 | 2000 | 1999 | 1998 | 1997
Number of items: 63.

2019

Strawbridge, R. J. et al. (2019) Carotid intima-media thickness: novel loci, sex-specific effects and genetic correlations with obesity and glucometabolic traits in UK Biobank. Arteriosclerosis, Thrombosis, and Vascular Biology, (Accepted for Publication)

Gray, S. et al. (2019) Do physical activity, commuting mode, cardiorespiratory fitness and sedentary behaviours modify the genetic predisposition to higher BMI? Findings from a UK Biobank study. International Journal of Obesity, 43, pp. 1526-1538. (doi:10.1038/s41366-019-0381-5) (PMID:31168053)

Ward, J. et al. (2019) The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function. Molecular Psychiatry, (doi:10.1038/s41380-019-0439-8) (PMID:31168069) (Early Online Publication)

Johnston, K. J.A., Adams, M. J., Nicholl, B. I. , Ward, J., Strawbridge, R. , Ferguson, A., McIntosh, A., Bailey, M. E.S. and Smith, D. J. (2019) Genome-wide association study of multisite chronic pain in UK Biobank. PLoS Genetics, 15(6), e1008164. (doi:10.1371/journal.pgen.1008164) (PMID:31194737) (PMCID:PMC6592570)

Morris, J. et al. (2019) Genetic variation in CADM2 as a link between psychological traits and obesity. Scientific Reports, 9, 7339. (doi:10.1038/s41598-019-43861-9) (PMID:31089183) (PMCID:PMC6517397)

Celis-Morales, C. A. et al. (2019) The combination of physical activity and sedentary behaviors modifies the genetic predisposition to obesity. Obesity, 27(4), pp. 653-661. (doi:10.1002/oby.22417) (PMID:30900409)

Strawbridge, R. J. et al. (2019) Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide. EBioMedicine, 41, pp. 517-525. (doi:10.1016/j.ebiom.2019.02.005) (PMID:30745170) (PMCID:PMC6442001)

Ward, J. et al. (2019) Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure. Translational Psychiatry, 9, 327. (doi:10.1038/s41398-019-0635-y)

2018

Wyse, C. A. et al. (2018) Population-level seasonality in cardiovascular mortality, blood pressure, BMI and inflammatory cells in UK Biobank. Annals of Medicine, 50(5), pp. 410-419. (doi:10.1080/07853890.2018.1472389) (PMID:29724143)

Strawbridge, R. et al. (2018) Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression. Translational Psychiatry, 8, 178. (doi:10.1038/s41398-018-0236-1) (PMID:30181555) (PMCID:PMC6123450)

Boakye, D., Wyse, C.A., Morales-Celis, C.A. , Biello, S.M. , Bailey, M.E.S. , Dare, S., Ward, J., Gill, J.M.R. , Pell, J.P. and Mackay, D.F. (2018) Tobacco exposure and sleep disturbance in 498 208 UK Biobank participants. Journal of Public Health, 40(3), pp. 517-526. (doi:10.1093/pubmed/fdx102) (PMID:29040744)

Ferguson, A. et al. (2018) Genome-wide association study of circadian rhythmicity in 71,500 UK Biobank participants and polygenic association with mood instability. EBioMedicine, 35, pp. 279-287. (doi:10.1016/j.ebiom.2018.08.004) (PMID:30120083) (PMCID:PMC6154782)

Lyall, L. M. et al. (2018) Association of disrupted circadian rhythmicity with mood disorders, subjective wellbeing, and cognitive function: a cross-sectional study of 91 105 participants from the UK Biobank. Lancet Psychiatry, 5(6), pp. 507-514. (doi:10.1016/S2215-0366(18)30139-1) (PMID:29776774)

Lyall, L. M. et al. (2018) Seasonality of depressive symptoms in women but not in men: a cross-sectional study in the UK Biobank cohort. Journal of Affective Disorders, 229, pp. 296-305. (doi:10.1016/j.jad.2017.12.106) (PMID:29329063)

Strawbridge, R. J. et al. (2018) Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort. Translational Psychiatry, 8, 39. (doi:10.1038/s41398-017-0079-1) (PMID:29391395) (PMCID:PMC5804026)

2017

Hector, R. D. et al. (2017) CDKL5 variants: improving our understanding of a rare neurological disorder. Neurology Genetics, 3(6), e200. (doi:10.1212/NXG.0000000000000200) (PMID:29264392) (PMCID:PMC5732004)

Ward, J. et al. (2017) Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with major depressive disorder, anxiety disorder and schizophrenia. Translational Psychiatry, 7, 1264. (doi:10.1038/s41398-017-0012-7) (PMID:29187730) (PMCID:PMC5802589)

Bahey, N. G., Gadalla, K. K.E. , McGonigal, R., Bailey, M. E.S. , Edgar, J. M. and Cobb, S. R. (2017) Reduced axonal diameter of peripheral nerve fibres in a mouse model of Rett syndrome. Neuroscience, 358, pp. 261-268. (doi:10.1016/j.neuroscience.2017.06.061)

Gadalla, K. K.E. , Vudhironarit, T., Hector, R. D. , Sinnett, S., Bahey, N. G., Bailey, M. E.S. , Gray, S. J. and Cobb, S. R. (2017) Development of a novel AAV gene therapy cassette with improved safety features and efficacy in a mouse model of Rett syndrome. Molecular Therapy: Methods and Clinical Development, 5, pp. 180-190. (doi:10.1016/j.omtm.2017.04.007) (PMID:28497075) (PMCID:PMC5423329)

Sinnett, S. E., Hector, R. D. , Gadalla, K. K.E. , Heindel, C., Chen, D., Zaric, V., Bailey, M. E.S. , Cobb, S. R. and Gray, S. J. (2017) Improved MECP2 gene therapy extends the survival of MeCP2-null mice without apparent toxicity after intracisternal delivery. Molecular Therapy: Methods and Clinical Development, 5, pp. 106-115. (doi:10.1016/j.omtm.2017.04.006) (PMID:28497072) (PMCID:PMC5424572)

Celis-Morales, C. et al. (2017) Sleep characteristics modify the association between genetic predisposition to obesity and anthropometric measurements in 119,679 UK Biobank participants. American Journal of Clinical Nutrition, 105(4), pp. 980-990. (doi:10.3945/ajcn.116.147231)

Hector, R. D. , Dando, O., Ritakari, T. E., Kind, P. C., Bailey, M. E.S. and Cobb, S. R. (2017) Characterisation of Cdkl5 transcript isoforms in rat. Gene, 603, pp. 21-26. (doi:10.1016/j.gene.2016.12.001) (PMID:27940108)

Gianfagna, F. et al. (2017) The role of neuromedin U in adiposity regulation. Haplotype analysis in European children from the IDEFICS Cohort. PLoS ONE, 12(2), e0172698. (doi:10.1371/journal.pone.0172698) (PMID:28235053) (PMCID:PMC5325300)

Celis-Morales, C. et al. (2017) Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants. International Journal of Obesity, 41, pp. 1761-1768. (doi:10.1038/ijo.2017.169) (PMID:28736445)

Wyse, C. A. et al. (2017) Adverse metabolic and mental health outcomes associated with shiftwork in a population-based study of 277,168 workers in UK biobank. Annals of Medicine, 49(5), pp. 411-420. (doi:10.1080/07853890.2017.1292045) (PMID:28166415)

2016

Ross, P. D. et al. (2016) Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes. Human Molecular Genetics, 25(20), pp. 4389-4404. (doi:10.1093/hmg/ddw269) (PMID:28173151)

Lyall, D. M. et al. (2016) Alzheimer disease genetic risk factor APOE e4, and cognitive abilities in 111,739 UK Biobank participants. Age and Ageing, 45(4), pp. 511-517. (doi:10.1093/ageing/afw068) (PMID:27103599)

Hector, R. D. , Dando, O., Landsberger, N., Kilstrup-Nielsen, C., Kind, P. C., Bailey, M. E.S. and Cobb, S. R. (2016) Characterisation of CDKL5 transcript isoforms in human and mouse. PLoS ONE, 11(6), e0157758. (doi:10.1371/journal.pone.0157758) (PMID:27315173) (PMCID:PMC4912119)

Smith, D.J. et al. (2016) Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci. Molecular Psychiatry, 21(6), pp. 749-757. (doi:10.1038/mp.2016.49) (PMID:27067015)

2015

Qi, Q. et al. (2015) Dietary intake, FTOGenetic variants, and adiposity: a combined analysis of over 16,000 children and adolescents. Diabetes, 64(7), pp. 2467-2476. (doi:10.2337/db14-1629) (PMID:25720386)

Gadalla, K. K. E. , Ross, P. D., Hector, R. D. , Bahey, N. G., Bailey, M. E.S. and Cobb, S. R. (2015) Gene therapy for Rett syndrome: prospects and challenges. Future Neurology, 10(5), pp. 467-484. (doi:10.2217/fnl.15.29)

Wardle, S. L., Bailey, M. E. , Kilikevicius, A., Malkova, D. , Wilson, R. H. , Venckunas, T. and Moran, C. (2015) Plasma microRNA levels differ between endurance and strength athletes. PLoS ONE, 10(4), e0122107. (doi:10.1371/journal.pone.0122107) (PMID:25881132) (PMCID:PMC4400105)

2014

Gadalla, K. K.E. , Ross, P. D., Riddell, J. S. , Bailey, M. E.S. and Cobb, S. R. (2014) Gait analysis in a Mecp2 knockout mouse model of Rett syndrome reveals early-onset and progressive motor deficits. PLoS ONE, 9(11), e112889. (doi:10.1371/journal.pone.0112889) (PMID:25392929) (PMCID:PMC4231076)

2013

Wang, G. et al. (2013) Association analysis of ACE and ACTN3 in elite caucasian and east Asian swimmers. Medicine and Science in Sports and Exercise, 45(5), pp. 892-900. (doi:10.1249/MSS.0b013e31827c501f)

Gadalla, K.K.E. et al. (2013) Improved survival and reduced phenotypic severity following AAV9/MECP2 gene transfer to neonatal and juvenile male Mecp2 knockout mice. Molecular Therapy, 21(1), pp. 18-30. (doi:10.1038/mt.2012.200) (PMID:23011033) (PMCID:PMC3536818)

Celis-Morales, C. A. , Ghouri, N., Bailey, M.E.S. , Sattar, N. and Gill, J. M.R. (2013) Should physical activity recommendations be ethnicity-specific? Evidence from a cross-sectional study of south Asian and European men. PLoS ONE, 8(12), e82568. (doi:10.1371/journal.pone.0082568) (PMID:24349313) (PMCID:PMC3859604)

Gianfagna, F. et al. (2013) Understanding the links among neuromedin U Gene, beta2-adrenoceptor gene and bone health: an observational study in European children. PLoS ONE, 8(8), e70632. (doi:10.1371/journal.pone.0070632) (PMID:23936460) (PMCID:PMC3731254)

2012

Celis-Morales, C. A. , Perez-Bravo, F., Ibanez, L., Salas, C., Bailey, M. E.S. and Gill, J. M.R. (2012) Objective vs. self-reported physical activity and sedentary time: effects of measurement method on relationships with risk biomarkers. PLoS ONE, 7(5), e36345. (doi:10.1371/journal.pone.0036345) (PMID:22590532) (PMCID:PMC3348936)

2011

Weng, S.-M., Bailey, M. E.S. and Cobb, S. R. (2011) Rett syndrome: from bed to bench. Pediatrics and Neonatology, 52(6), pp. 309-316. (doi:10.1016/j.pedneo.2011.08.002)

Gadalla, K.K.E., Bailey, M.E.S. and Cobb, S.R. (2011) MeCP2 and Rett syndrome: reversibility and potential avenues for therapy. Biochemical Journal, 439(1), pp. 1-14. (doi:10.1042/BJ20110648)

Weng, S.-M., McLeod, F., Bailey, M.E.S. and Cobb, S.R. (2011) Synaptic plasticity deficits in an experimental model of Rett Syndrome: LTP saturation and its pharmacological reversal. Neuroscience, 180, pp. 314-321. (doi:10.1016/j.neuroscience.2011.01.061)

Koni, A.C., Scott, R.A., Wang, G., Bailey, M.E.S. , Peplies, J., Bammann, K. and Pitsiladis, Y.P. (2011) DNA yield and quality of saliva samples and suitability for large scale epidemiological studies in children. International Journal of Obesity, 35(Suppl.), S113-S118.

Celis-Morales, C.A. , Perez-Bravo, F., Ibañes, L., Sanzana, R., Hormazabal, E., Ulloa, N., Calvo, C., Bailey, M.E.S. and Gill, J.M.R. (2011) Insulin resistance in Chileans of European and indigenous descent: evidence for an ethnicity x environment interaction. PLoS ONE, 6(9), e24690. (doi:10.1371/journal.pone.0024690)

2010

Wilson, R.H., Moran, C.N., Cole, J., Pitsiladis, Y.P. and Bailey, M.E.S. (2010) Evolutionary history of the ADRB2 gene in humans. American Journal of Human Genetics, 86(3), pp. 490-493. (doi:10.1016/j.ajhg.2010.01.031)

Neul, J.L. et al. (2010) Rett Syndrome: Revised diagnostic criteria and nomenclature. Annals of Neurology, 68(6), pp. 944-950. (doi:10.1002/ana.22124)

Scott, R.A. et al. (2010) FTO genotype and adiposity in children: physical activity levels influence the effect of the risk genotype in adolescent males. European Journal of Human Genetics, 18(12), pp. 1339-1343. (doi:10.1038/ejhg.2010.131)

2009

Todd, A. J. , Polgár, E., Watt, C., Bailey, M. E.S. and Watanabe, M. (2009) Neurokinin 1 receptor-expressing projection neurons in laminae III and IV of the rat spinal cord have synaptic AMPA receptors that contain GluR2, GluR3 and GluR4 subunits. European Journal of Neuroscience, 29(4), pp. 718-726. (doi:10.1111/j.1460-9568.2009.06633.x) (PMID:19200070) (PMCID:PMC2695158)

Morrison, A. W., Bailey, M.E.S. and Morrison, G. A. J. (2009) Familial Ménière's disease: clinical and genetic aspects. Journal of Laryngology and Otology, 123(01), pp. 29-37. (doi:10.1017/S0022215108002788)

2007

Archer, H. et al. (2007) Correlation between clinical severity in patients with Rett Syndrome with a p.R168X or p.T158M MECP2 mutation, and the direction and degree of skewing of X-chromosome inactivation. Journal of Medical Genetics, 44, pp. 148-152. (doi:10.1136/jmg.2006.045260)

Lagou, V., Manios, Y., Moran, C., Bailey, M., Grammatikaki, E., Oikonomou, E., Ioannou, E., Moschonis, G., Wilson, R. and Pitsiladis, Y. (2007) Developmental changes in adiposity in toddlers and preschoolers in the GENESIS study and associations with the ACE I/D polymorphism. International Journal of Obesity, 31, pp. 1052-1060. (doi:10.1038/sj.ijo.0803605)

Moran, C., Yang, N., Bailey, M., Tsiokanos, A., Jamurtas, A., MacArthur, D., North, K., Pitsiladis, Y. and Wilson, R. (2007) Association analysis of the ACTN3 R577X polymorphism and complex quantitative body composition and performance phenotypes in adolescent Greeks. European Journal of Human Genetics, 15, pp. 88-93. (doi:10.1038/sj.ejhg.5201724)

2006

Knudsen, G., Neilson, T., Pedersen, J., Kerr, A., Schwartz, M., Hulten, M., Bailey, M. and Orstavik, K. (2006) Increased skewing of X chromosome inactivation in Rett syndrome patients and their mothers. European Journal of Human Genetics, 14, pp. 1189-1194. (doi:10.1038/sj.ejhg.5201682)

Moran, C., Vassilopoulos, C., Tsiokanos, A., Jamurtas, A., Bailey, M., Montgomery, H., Wilson, R. and Pitsiladis, Y. (2006) The associations of ACE polymorphisms with physical, physiological and skill parameters in adolescents. European Journal of Human Genetics, 14, pp. 332-339.

2005

Charman, T. et al. (2005) Dimensional phenotypic analysis and functional categorisation of mutations reveal novel genotype-phenotype associations in Rett syndrome. European Journal of Human Genetics, 13, pp. 1121-1130. (doi:10.1038/sj.ejhg.5201471) (PMID:16077736)

Jian, L., Archer, H., Ravine, D., Kerr, A., de Klerk, N., Christodoulou, J., Bailey, M. , Laurvick, C. and Leonard, H. (2005) p.R270X MECP2 mutation and mortality in Rett syndrome. European Journal of Human Genetics, 13, pp. 1235-1238. (doi:10.1038/sj.ejhg.5201479)

Moran, C.N., Vassilopoulos, C., Tsiokanos, A., Jamurtas, A., Bailey, M.E.S. , Wilson, R. and Pitsiladis, Y. (2005) Effects of interaction between angiotensin I-converting enzyme polymorphisms and lifestyle on adiposity in adolescent Greeks. Obesity Research, 13, pp. 1499-1504. (doi:10.1038/oby.2005.181) (PMID:16222048)

2000

Boucher, C. A., Winchester, C. L., Hamilton, G. M., Winter, A. D., Johnson, K. J. and Bailey, M. E.S. (2000) Structure, mapping and expression of the human gene encoding the homeodomain protein, SIX2. Gene, 247(1-2), pp. 145-151. (doi:10.1016/S0378-1119(00)00105-0) (PMID:10773454)

Xiang, F., Buervenich, S., Nicolao, P., Bailey, M. E.S. , Zhang, Z. and Anvret, M. (2000) Mutation screening in Rett syndrome patients. Journal of Medical Genetics, 37(4), pp. 250-255. (doi:10.1136/jmg.37.4.250) (PMID:10745042) (PMCID:PMC1734556)

1999

Bailey, M. E.S. , Albrecht, B. E., Johnson, K. J. and Darlison, M. G. (1999) Genetic linkage and radiation hybrid mapping of the three human GABAC receptor ρ subunit genes: GABRR1, GABRR2 and GABRR3. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1447(2-3), pp. 307-312. (doi:10.1016/S0167-4781(99)00167-0)

Bailey, M. E.S. , Matthews, D. A., Riley, B. P., Albrecht, B. E., Kostrzewa, M., Hicks, A. A., Harris, R., Müller, U., Darlison, M. G. and Johnson, K. J. (1999) Genomic mapping and evolution of human GABA A receptor subunit gene clusters. Mammalian Genome, 10(8), pp. 839-843. (doi:10.1007/s003359901101) (PMID:10430673)

Moncrieff, C. L., Bailey, M. E.S. , Morrison, N. and Johnson, K. J. (1999) Cloning and chromosomal localization of human Cdc42-binding protein kinase β. Genomics, 57(2), pp. 297-300. (doi:10.1006/geno.1999.5769)

1998

Burden, A. D., Hodgins, M., Tillman, D., Javed, S., Connor, M. and Bailey, M. (1998) Genetics of psoriasis: paternal inheritance and a locus on chromosome 6p. Journal of Investigative Dermatology, 110(6), pp. 958-960. (doi:10.1046/j.1523-1747.1998.00213.x) (PMID:9620305)

1997

Crowe, R. R., Wang, Z., Noyes, R., Albrecht, B. E., Darlison, M. G., Bailey, M. E.S. , Johnson, K. J. and Zoega, T. (1997) Candidate gene study of eight GABAA receptor subunits in panic disorder. American Journal of Psychiatry, 154(8), pp. 1096-1100. (doi:10.1176/ajp.154.8.1096) (PMID:9247395)

This list was generated on Thu Dec 5 05:47:14 2019 GMT.
Jump to: Articles
Number of items: 63.

Articles

Strawbridge, R. J. et al. (2019) Carotid intima-media thickness: novel loci, sex-specific effects and genetic correlations with obesity and glucometabolic traits in UK Biobank. Arteriosclerosis, Thrombosis, and Vascular Biology, (Accepted for Publication)

Gray, S. et al. (2019) Do physical activity, commuting mode, cardiorespiratory fitness and sedentary behaviours modify the genetic predisposition to higher BMI? Findings from a UK Biobank study. International Journal of Obesity, 43, pp. 1526-1538. (doi:10.1038/s41366-019-0381-5) (PMID:31168053)

Ward, J. et al. (2019) The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function. Molecular Psychiatry, (doi:10.1038/s41380-019-0439-8) (PMID:31168069) (Early Online Publication)

Johnston, K. J.A., Adams, M. J., Nicholl, B. I. , Ward, J., Strawbridge, R. , Ferguson, A., McIntosh, A., Bailey, M. E.S. and Smith, D. J. (2019) Genome-wide association study of multisite chronic pain in UK Biobank. PLoS Genetics, 15(6), e1008164. (doi:10.1371/journal.pgen.1008164) (PMID:31194737) (PMCID:PMC6592570)

Morris, J. et al. (2019) Genetic variation in CADM2 as a link between psychological traits and obesity. Scientific Reports, 9, 7339. (doi:10.1038/s41598-019-43861-9) (PMID:31089183) (PMCID:PMC6517397)

Celis-Morales, C. A. et al. (2019) The combination of physical activity and sedentary behaviors modifies the genetic predisposition to obesity. Obesity, 27(4), pp. 653-661. (doi:10.1002/oby.22417) (PMID:30900409)

Strawbridge, R. J. et al. (2019) Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide. EBioMedicine, 41, pp. 517-525. (doi:10.1016/j.ebiom.2019.02.005) (PMID:30745170) (PMCID:PMC6442001)

Ward, J. et al. (2019) Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure. Translational Psychiatry, 9, 327. (doi:10.1038/s41398-019-0635-y)

Wyse, C. A. et al. (2018) Population-level seasonality in cardiovascular mortality, blood pressure, BMI and inflammatory cells in UK Biobank. Annals of Medicine, 50(5), pp. 410-419. (doi:10.1080/07853890.2018.1472389) (PMID:29724143)

Strawbridge, R. et al. (2018) Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression. Translational Psychiatry, 8, 178. (doi:10.1038/s41398-018-0236-1) (PMID:30181555) (PMCID:PMC6123450)

Boakye, D., Wyse, C.A., Morales-Celis, C.A. , Biello, S.M. , Bailey, M.E.S. , Dare, S., Ward, J., Gill, J.M.R. , Pell, J.P. and Mackay, D.F. (2018) Tobacco exposure and sleep disturbance in 498 208 UK Biobank participants. Journal of Public Health, 40(3), pp. 517-526. (doi:10.1093/pubmed/fdx102) (PMID:29040744)

Ferguson, A. et al. (2018) Genome-wide association study of circadian rhythmicity in 71,500 UK Biobank participants and polygenic association with mood instability. EBioMedicine, 35, pp. 279-287. (doi:10.1016/j.ebiom.2018.08.004) (PMID:30120083) (PMCID:PMC6154782)

Lyall, L. M. et al. (2018) Association of disrupted circadian rhythmicity with mood disorders, subjective wellbeing, and cognitive function: a cross-sectional study of 91 105 participants from the UK Biobank. Lancet Psychiatry, 5(6), pp. 507-514. (doi:10.1016/S2215-0366(18)30139-1) (PMID:29776774)

Lyall, L. M. et al. (2018) Seasonality of depressive symptoms in women but not in men: a cross-sectional study in the UK Biobank cohort. Journal of Affective Disorders, 229, pp. 296-305. (doi:10.1016/j.jad.2017.12.106) (PMID:29329063)

Strawbridge, R. J. et al. (2018) Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort. Translational Psychiatry, 8, 39. (doi:10.1038/s41398-017-0079-1) (PMID:29391395) (PMCID:PMC5804026)

Hector, R. D. et al. (2017) CDKL5 variants: improving our understanding of a rare neurological disorder. Neurology Genetics, 3(6), e200. (doi:10.1212/NXG.0000000000000200) (PMID:29264392) (PMCID:PMC5732004)

Ward, J. et al. (2017) Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with major depressive disorder, anxiety disorder and schizophrenia. Translational Psychiatry, 7, 1264. (doi:10.1038/s41398-017-0012-7) (PMID:29187730) (PMCID:PMC5802589)

Bahey, N. G., Gadalla, K. K.E. , McGonigal, R., Bailey, M. E.S. , Edgar, J. M. and Cobb, S. R. (2017) Reduced axonal diameter of peripheral nerve fibres in a mouse model of Rett syndrome. Neuroscience, 358, pp. 261-268. (doi:10.1016/j.neuroscience.2017.06.061)

Gadalla, K. K.E. , Vudhironarit, T., Hector, R. D. , Sinnett, S., Bahey, N. G., Bailey, M. E.S. , Gray, S. J. and Cobb, S. R. (2017) Development of a novel AAV gene therapy cassette with improved safety features and efficacy in a mouse model of Rett syndrome. Molecular Therapy: Methods and Clinical Development, 5, pp. 180-190. (doi:10.1016/j.omtm.2017.04.007) (PMID:28497075) (PMCID:PMC5423329)

Sinnett, S. E., Hector, R. D. , Gadalla, K. K.E. , Heindel, C., Chen, D., Zaric, V., Bailey, M. E.S. , Cobb, S. R. and Gray, S. J. (2017) Improved MECP2 gene therapy extends the survival of MeCP2-null mice without apparent toxicity after intracisternal delivery. Molecular Therapy: Methods and Clinical Development, 5, pp. 106-115. (doi:10.1016/j.omtm.2017.04.006) (PMID:28497072) (PMCID:PMC5424572)

Celis-Morales, C. et al. (2017) Sleep characteristics modify the association between genetic predisposition to obesity and anthropometric measurements in 119,679 UK Biobank participants. American Journal of Clinical Nutrition, 105(4), pp. 980-990. (doi:10.3945/ajcn.116.147231)

Hector, R. D. , Dando, O., Ritakari, T. E., Kind, P. C., Bailey, M. E.S. and Cobb, S. R. (2017) Characterisation of Cdkl5 transcript isoforms in rat. Gene, 603, pp. 21-26. (doi:10.1016/j.gene.2016.12.001) (PMID:27940108)

Gianfagna, F. et al. (2017) The role of neuromedin U in adiposity regulation. Haplotype analysis in European children from the IDEFICS Cohort. PLoS ONE, 12(2), e0172698. (doi:10.1371/journal.pone.0172698) (PMID:28235053) (PMCID:PMC5325300)

Celis-Morales, C. et al. (2017) Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants. International Journal of Obesity, 41, pp. 1761-1768. (doi:10.1038/ijo.2017.169) (PMID:28736445)

Wyse, C. A. et al. (2017) Adverse metabolic and mental health outcomes associated with shiftwork in a population-based study of 277,168 workers in UK biobank. Annals of Medicine, 49(5), pp. 411-420. (doi:10.1080/07853890.2017.1292045) (PMID:28166415)

Ross, P. D. et al. (2016) Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes. Human Molecular Genetics, 25(20), pp. 4389-4404. (doi:10.1093/hmg/ddw269) (PMID:28173151)

Lyall, D. M. et al. (2016) Alzheimer disease genetic risk factor APOE e4, and cognitive abilities in 111,739 UK Biobank participants. Age and Ageing, 45(4), pp. 511-517. (doi:10.1093/ageing/afw068) (PMID:27103599)

Hector, R. D. , Dando, O., Landsberger, N., Kilstrup-Nielsen, C., Kind, P. C., Bailey, M. E.S. and Cobb, S. R. (2016) Characterisation of CDKL5 transcript isoforms in human and mouse. PLoS ONE, 11(6), e0157758. (doi:10.1371/journal.pone.0157758) (PMID:27315173) (PMCID:PMC4912119)

Smith, D.J. et al. (2016) Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci. Molecular Psychiatry, 21(6), pp. 749-757. (doi:10.1038/mp.2016.49) (PMID:27067015)

Qi, Q. et al. (2015) Dietary intake, FTOGenetic variants, and adiposity: a combined analysis of over 16,000 children and adolescents. Diabetes, 64(7), pp. 2467-2476. (doi:10.2337/db14-1629) (PMID:25720386)

Gadalla, K. K. E. , Ross, P. D., Hector, R. D. , Bahey, N. G., Bailey, M. E.S. and Cobb, S. R. (2015) Gene therapy for Rett syndrome: prospects and challenges. Future Neurology, 10(5), pp. 467-484. (doi:10.2217/fnl.15.29)

Wardle, S. L., Bailey, M. E. , Kilikevicius, A., Malkova, D. , Wilson, R. H. , Venckunas, T. and Moran, C. (2015) Plasma microRNA levels differ between endurance and strength athletes. PLoS ONE, 10(4), e0122107. (doi:10.1371/journal.pone.0122107) (PMID:25881132) (PMCID:PMC4400105)

Gadalla, K. K.E. , Ross, P. D., Riddell, J. S. , Bailey, M. E.S. and Cobb, S. R. (2014) Gait analysis in a Mecp2 knockout mouse model of Rett syndrome reveals early-onset and progressive motor deficits. PLoS ONE, 9(11), e112889. (doi:10.1371/journal.pone.0112889) (PMID:25392929) (PMCID:PMC4231076)

Wang, G. et al. (2013) Association analysis of ACE and ACTN3 in elite caucasian and east Asian swimmers. Medicine and Science in Sports and Exercise, 45(5), pp. 892-900. (doi:10.1249/MSS.0b013e31827c501f)

Gadalla, K.K.E. et al. (2013) Improved survival and reduced phenotypic severity following AAV9/MECP2 gene transfer to neonatal and juvenile male Mecp2 knockout mice. Molecular Therapy, 21(1), pp. 18-30. (doi:10.1038/mt.2012.200) (PMID:23011033) (PMCID:PMC3536818)

Celis-Morales, C. A. , Ghouri, N., Bailey, M.E.S. , Sattar, N. and Gill, J. M.R. (2013) Should physical activity recommendations be ethnicity-specific? Evidence from a cross-sectional study of south Asian and European men. PLoS ONE, 8(12), e82568. (doi:10.1371/journal.pone.0082568) (PMID:24349313) (PMCID:PMC3859604)

Gianfagna, F. et al. (2013) Understanding the links among neuromedin U Gene, beta2-adrenoceptor gene and bone health: an observational study in European children. PLoS ONE, 8(8), e70632. (doi:10.1371/journal.pone.0070632) (PMID:23936460) (PMCID:PMC3731254)

Celis-Morales, C. A. , Perez-Bravo, F., Ibanez, L., Salas, C., Bailey, M. E.S. and Gill, J. M.R. (2012) Objective vs. self-reported physical activity and sedentary time: effects of measurement method on relationships with risk biomarkers. PLoS ONE, 7(5), e36345. (doi:10.1371/journal.pone.0036345) (PMID:22590532) (PMCID:PMC3348936)

Weng, S.-M., Bailey, M. E.S. and Cobb, S. R. (2011) Rett syndrome: from bed to bench. Pediatrics and Neonatology, 52(6), pp. 309-316. (doi:10.1016/j.pedneo.2011.08.002)

Gadalla, K.K.E., Bailey, M.E.S. and Cobb, S.R. (2011) MeCP2 and Rett syndrome: reversibility and potential avenues for therapy. Biochemical Journal, 439(1), pp. 1-14. (doi:10.1042/BJ20110648)

Weng, S.-M., McLeod, F., Bailey, M.E.S. and Cobb, S.R. (2011) Synaptic plasticity deficits in an experimental model of Rett Syndrome: LTP saturation and its pharmacological reversal. Neuroscience, 180, pp. 314-321. (doi:10.1016/j.neuroscience.2011.01.061)

Koni, A.C., Scott, R.A., Wang, G., Bailey, M.E.S. , Peplies, J., Bammann, K. and Pitsiladis, Y.P. (2011) DNA yield and quality of saliva samples and suitability for large scale epidemiological studies in children. International Journal of Obesity, 35(Suppl.), S113-S118.

Celis-Morales, C.A. , Perez-Bravo, F., Ibañes, L., Sanzana, R., Hormazabal, E., Ulloa, N., Calvo, C., Bailey, M.E.S. and Gill, J.M.R. (2011) Insulin resistance in Chileans of European and indigenous descent: evidence for an ethnicity x environment interaction. PLoS ONE, 6(9), e24690. (doi:10.1371/journal.pone.0024690)

Wilson, R.H., Moran, C.N., Cole, J., Pitsiladis, Y.P. and Bailey, M.E.S. (2010) Evolutionary history of the ADRB2 gene in humans. American Journal of Human Genetics, 86(3), pp. 490-493. (doi:10.1016/j.ajhg.2010.01.031)

Neul, J.L. et al. (2010) Rett Syndrome: Revised diagnostic criteria and nomenclature. Annals of Neurology, 68(6), pp. 944-950. (doi:10.1002/ana.22124)

Scott, R.A. et al. (2010) FTO genotype and adiposity in children: physical activity levels influence the effect of the risk genotype in adolescent males. European Journal of Human Genetics, 18(12), pp. 1339-1343. (doi:10.1038/ejhg.2010.131)

Todd, A. J. , Polgár, E., Watt, C., Bailey, M. E.S. and Watanabe, M. (2009) Neurokinin 1 receptor-expressing projection neurons in laminae III and IV of the rat spinal cord have synaptic AMPA receptors that contain GluR2, GluR3 and GluR4 subunits. European Journal of Neuroscience, 29(4), pp. 718-726. (doi:10.1111/j.1460-9568.2009.06633.x) (PMID:19200070) (PMCID:PMC2695158)

Morrison, A. W., Bailey, M.E.S. and Morrison, G. A. J. (2009) Familial Ménière's disease: clinical and genetic aspects. Journal of Laryngology and Otology, 123(01), pp. 29-37. (doi:10.1017/S0022215108002788)

Archer, H. et al. (2007) Correlation between clinical severity in patients with Rett Syndrome with a p.R168X or p.T158M MECP2 mutation, and the direction and degree of skewing of X-chromosome inactivation. Journal of Medical Genetics, 44, pp. 148-152. (doi:10.1136/jmg.2006.045260)

Lagou, V., Manios, Y., Moran, C., Bailey, M., Grammatikaki, E., Oikonomou, E., Ioannou, E., Moschonis, G., Wilson, R. and Pitsiladis, Y. (2007) Developmental changes in adiposity in toddlers and preschoolers in the GENESIS study and associations with the ACE I/D polymorphism. International Journal of Obesity, 31, pp. 1052-1060. (doi:10.1038/sj.ijo.0803605)

Moran, C., Yang, N., Bailey, M., Tsiokanos, A., Jamurtas, A., MacArthur, D., North, K., Pitsiladis, Y. and Wilson, R. (2007) Association analysis of the ACTN3 R577X polymorphism and complex quantitative body composition and performance phenotypes in adolescent Greeks. European Journal of Human Genetics, 15, pp. 88-93. (doi:10.1038/sj.ejhg.5201724)

Knudsen, G., Neilson, T., Pedersen, J., Kerr, A., Schwartz, M., Hulten, M., Bailey, M. and Orstavik, K. (2006) Increased skewing of X chromosome inactivation in Rett syndrome patients and their mothers. European Journal of Human Genetics, 14, pp. 1189-1194. (doi:10.1038/sj.ejhg.5201682)

Moran, C., Vassilopoulos, C., Tsiokanos, A., Jamurtas, A., Bailey, M., Montgomery, H., Wilson, R. and Pitsiladis, Y. (2006) The associations of ACE polymorphisms with physical, physiological and skill parameters in adolescents. European Journal of Human Genetics, 14, pp. 332-339.

Charman, T. et al. (2005) Dimensional phenotypic analysis and functional categorisation of mutations reveal novel genotype-phenotype associations in Rett syndrome. European Journal of Human Genetics, 13, pp. 1121-1130. (doi:10.1038/sj.ejhg.5201471) (PMID:16077736)

Jian, L., Archer, H., Ravine, D., Kerr, A., de Klerk, N., Christodoulou, J., Bailey, M. , Laurvick, C. and Leonard, H. (2005) p.R270X MECP2 mutation and mortality in Rett syndrome. European Journal of Human Genetics, 13, pp. 1235-1238. (doi:10.1038/sj.ejhg.5201479)

Moran, C.N., Vassilopoulos, C., Tsiokanos, A., Jamurtas, A., Bailey, M.E.S. , Wilson, R. and Pitsiladis, Y. (2005) Effects of interaction between angiotensin I-converting enzyme polymorphisms and lifestyle on adiposity in adolescent Greeks. Obesity Research, 13, pp. 1499-1504. (doi:10.1038/oby.2005.181) (PMID:16222048)

Boucher, C. A., Winchester, C. L., Hamilton, G. M., Winter, A. D., Johnson, K. J. and Bailey, M. E.S. (2000) Structure, mapping and expression of the human gene encoding the homeodomain protein, SIX2. Gene, 247(1-2), pp. 145-151. (doi:10.1016/S0378-1119(00)00105-0) (PMID:10773454)

Xiang, F., Buervenich, S., Nicolao, P., Bailey, M. E.S. , Zhang, Z. and Anvret, M. (2000) Mutation screening in Rett syndrome patients. Journal of Medical Genetics, 37(4), pp. 250-255. (doi:10.1136/jmg.37.4.250) (PMID:10745042) (PMCID:PMC1734556)

Bailey, M. E.S. , Albrecht, B. E., Johnson, K. J. and Darlison, M. G. (1999) Genetic linkage and radiation hybrid mapping of the three human GABAC receptor ρ subunit genes: GABRR1, GABRR2 and GABRR3. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1447(2-3), pp. 307-312. (doi:10.1016/S0167-4781(99)00167-0)

Bailey, M. E.S. , Matthews, D. A., Riley, B. P., Albrecht, B. E., Kostrzewa, M., Hicks, A. A., Harris, R., Müller, U., Darlison, M. G. and Johnson, K. J. (1999) Genomic mapping and evolution of human GABA A receptor subunit gene clusters. Mammalian Genome, 10(8), pp. 839-843. (doi:10.1007/s003359901101) (PMID:10430673)

Moncrieff, C. L., Bailey, M. E.S. , Morrison, N. and Johnson, K. J. (1999) Cloning and chromosomal localization of human Cdc42-binding protein kinase β. Genomics, 57(2), pp. 297-300. (doi:10.1006/geno.1999.5769)

Burden, A. D., Hodgins, M., Tillman, D., Javed, S., Connor, M. and Bailey, M. (1998) Genetics of psoriasis: paternal inheritance and a locus on chromosome 6p. Journal of Investigative Dermatology, 110(6), pp. 958-960. (doi:10.1046/j.1523-1747.1998.00213.x) (PMID:9620305)

Crowe, R. R., Wang, Z., Noyes, R., Albrecht, B. E., Darlison, M. G., Bailey, M. E.S. , Johnson, K. J. and Zoega, T. (1997) Candidate gene study of eight GABAA receptor subunits in panic disorder. American Journal of Psychiatry, 154(8), pp. 1096-1100. (doi:10.1176/ajp.154.8.1096) (PMID:9247395)

This list was generated on Thu Dec 5 05:47:14 2019 GMT.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Enhancing efficiency of molecular therapies for Rett syndrome
    Rett Syndrome Association Scotland
    2018 - 2023
     
  • A gene therapy consortium to develop and evaluate next generation gene therapy approaches in Rett syndrome
    Rett Syndrome Research Trust
    2017 - 2018
     
  • Optimising MECP2 trans splicing for human translation
    Rett Syndrome Research Trust
    2017 - 2018
     
  • Trans-Splicing as a novel therapy for CDKL5 disorder
    CDKL5 UK
    2016 - 2017
     
  • Polygenic risk for depression and neuroticism as predictors of antidepressant response
    Chief Scientist Office
    2016 - 2016
     
  • Novel Gene-Based Therapeutic Approaches in Rett Syndrome and Allied Disorders
    Rett Syndrome Association Scotland
    2016 - 2018
     
  • Rett Syndrome Research
    Rett Syndrome Association Scotland
    2016 - 2018
     
  • Spliceosome-Mediated RNA Trans-Splicing Therapy in Rett syndrome
    Rett Syndrome Research Trust
    2016 - 2016
     
  • Developing and evaluating novel gene therapy approaches in Rett syndrome
    Chief Scientist Office
    2014 - 2016
     
  • Gene Therapy Consortium
    Rett Syndrome Research Trust
    2014 - 2017
     
  • Gene Therapy Consortium
    Rosetrees Trust
    2014 - 2017
     
  • Gene Therapy Consortium
    The Stoneygate Trust
    2014 - 2017
     
  • Is Protein Therapy a Viable Strategy in Rett Syndrome?
    Rett Syndrome Association Scotland
    2013 - 2016
     
  • Assessing the potential for gene therapy in Rett syndrome
    Rett Syndrome Association Scotland
    2011 - 2013
     
  • Improving the functioning of neurons in Rett Syndrome - linking basic neurobiology and therapeutic strategies
    Rett Syndrome Association Scotland
    2009 - 2011
     
  • An integrative approach to the identification of novel therapeutic targets in Rett syndrome
    Rett Syndrome Association Scotland
    2007 - 2009
     
  • Continued genotype-phenotype studies of Rett syndrome
    Rett Syndrome Association Scotland
    2006 - 2007
     
  • Molecular mechanisms controlling the regenerative response of dorsal root axons following avulsion injury
    Neurosciences Foundation
    2006 - 2008
     
  • Identification of genes predisposing to Meniere disease
    Deafness Research UK
    2005 - 2008
     
  • Extending genotype-phenotype studies of Rett syndrome using the British Isles Rett Survey database and the Rett Syndrome Behaviour Question.
    Rett Syndrome Research Trust
    2004 - 2006
     
  • Identification of genes predisposing to Meniere disease
    Defeating Deafness
    2003 - 2005
     

Supervision

Teaching

PGT teaching: Programme Director, MSc Bioinformatics, Polyomics and Systems Biology

UG teaching: Course leader, Level 4 Human Molecular Genetics option

 

Other teaching focuses on genetics, molecular genetics and molecular pathology of human disorders and models of disease in other organisms, as well as on genomics and functional genomics.


Research datasets

Jump to: 2019
Number of items: 1.

2019

Johnston, K., Adams, M. J., Nicholl, B. , Ward, J., Strawbridge, R. , Ferguson, A., McIntosh, A. M., Bailey, M. and Smith, D. (2019) Genome-wide association summary statistics for a genome-wide association study of multisite chronic pain. [Data Collection]

This list was generated on Thu Dec 5 10:44:39 2019 GMT.

Additional information

Grant Advisory Board

  • 2009 - present: International Rett Syndrome Foundation (IRSF) - Member of Scientific Review Board
  • 2006 - present: RettSearch - Clinical Trials Consortium, Invited Member
  • 2006 - present: Rett Syndrome Association Scotland - Member of Board of Medical Advisors
  • 2004 - present: IRSA International Rett Syndrome Phenotype Database - Member of reference panel of experts

Invited International Presentations

  • 2006: San Francisco, USA - NIH-Sponsored Workshop - Clinical Trials in Rett Syndrome: Potential for Early Intervention.

Prizes, Awards and Distinctions

  • 1998: SHERT/Cruden Scholarship

Professional Learned Society

  • 2005 - present: American Society of Human Genetics - Member
  • 2001 - present: Human Genome Organisation (HUGO) - Member

Research Fellowship

  • 1998 - 2002: Epilepsy Research Foundation - Joy Chisholm Fellowship