Dr Suzie Humphrey

  • Technician (Bacteriology)

email: Suzie.Humphrey@glasgow.ac.uk

Institute of Infection, Inflammation and Immunity, Sir Graeme Davies Building, Room B232, 120 University Place, University of Glasgow, G12 8TA

ORCID iDhttps://orcid.org/0000-0002-9893-3209

Biography

I am a core technician in the Department of Bacteriology, with a particular focus on managing Health and Safety. Prior to becoming a technician, I was a PDRA for more than seven years. During this time, my research involved investigating host-pathogen interactions in bacteria associated with foodborne disease, and investigating the impact of bacteriophage-driven horizontal gene transfer in influencing the evolution and virulence of the clinically-relevant pathogen Staphylococcus aureus. I have extensive experience in molecular biology, including generating mutants and expression plasmids in a variety of host species, as well as considerable experience in tissue culture, confocal microscopy, flow cytometry, Southern blotting, SDS-PAGE, western blotting, RNA extraction, and qRT-PCR. I am now using these skills to provide broad support to a variety of research projects across the department.

Publications

List by: Type | Date

Jump to: 2021 | 2019 | 2017 | 2016
Number of items: 8.

2021

Fillol-Salom, A. , Bacigalupe, R., Humphrey, S. , Chiang, Y. N., Chen, J. and Penadés, J. R. (2021) Lateral transduction is inherent to the life cycle of the archetypical Salmonella phage P22. Nature Communications, 12, 6510. (doi: 10.1038/s41467-021-26520-4) (PMID:34751192) (PMCID:PMC8575938)

Humphrey, S. , Fillol-Salom, A. , Quiles-Puchalt, N., Ibarra-Chávez, R., Haag, A. F. , Chen, J. and Penadés, J. R. (2021) Bacterial chromosomal mobility via lateral transduction exceeds that of classical mobile genetic elements. Nature Communications, 12, 6509. (doi: 10.1038/s41467-021-26004-5) (PMID:34750368) (PMCID:PMC8575950)

Humphrey, S. , San Millán, Á., Toll-Riera, M., Connolly, J., Flor-Duro, A., Chen, J., Ubeda, C., MacLean, R. C. and Penadés, J. R. (2021) Staphylococcal phages and pathogenicity islands drive plasmid evolution. Nature Communications, 12, 5845. (doi: 10.1038/s41467-021-26101-5) (PMID:34615859) (PMCID:PMC8494744)

2019

Ciges-Tomas, J. R., Alite, C., Humphrey, S. , Donderis, J., Bowring, J. , Salvatella, X., Penadés, J. R. and Marina, A. (2019) The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature. Nature Communications, 10, 3676. (doi: 10.1038/s41467-019-11504-2) (PMID:31417084) (PMCID:PMC6695447)

2017

Alite, C., Humphrey, S. , Donderis, J., Maiques, E., Ciges-Tomas, J. R., Penadés, J. R. and Marina, A. (2017) Dissecting the link between the enzymatic activity and the SaPI inducing capacity of the phage 80α dUTPase. Scientific Reports, 7, 11234. (doi: 10.1038/s41598-017-11234-9) (PMID:28894239) (PMCID:PMC5593958)

de Vries, S. P.W. et al. (2017) Genome-wide fitness analyses of the foodborne pathogen Campylobacter jejuni in in vitro and in vivo models. Scientific Reports, 7, 1251. (doi: 10.1038/s41598-017-01133-4) (PMID:28455506) (PMCID:PMC5430854)

Martínez-Rubio, R., Quiles-Puchalt, N., Martí, M., Humphrey, S. , Ram, G., Smyth, D., Chen, J., Novick, R. P. and Penadés, J. R. (2017) Phage inducible islands in the gram-positive cocci. ISME Journal, 11(4), pp. 1029-1042. (doi: 10.1038/ismej.2016.163) (PMID:27959343) (PMCID:PMC5363835)

2016

Maiques, E., Quiles-Puchalt, N., Donderis, J., Ciges-Tomas, J. R., Alite, C., Bowring, J. Z. , Humphrey, S. , Penadés, J. R. and Marina, A. (2016) Another look at the mechanism involving trimeric dUTPases in Staphylococcus aureus pathogenicity island induction involves novel players in the party. Nucleic Acids Research, 44(11), pp. 5457-5469. (doi: 10.1093/nar/gkw317) (PMID:27112567) (PMCID:PMC4914113)

This list was generated on Sat Jan 28 07:05:53 2023 GMT.
Jump to: Articles
Number of items: 8.

Articles

Fillol-Salom, A. , Bacigalupe, R., Humphrey, S. , Chiang, Y. N., Chen, J. and Penadés, J. R. (2021) Lateral transduction is inherent to the life cycle of the archetypical Salmonella phage P22. Nature Communications, 12, 6510. (doi: 10.1038/s41467-021-26520-4) (PMID:34751192) (PMCID:PMC8575938)

Humphrey, S. , Fillol-Salom, A. , Quiles-Puchalt, N., Ibarra-Chávez, R., Haag, A. F. , Chen, J. and Penadés, J. R. (2021) Bacterial chromosomal mobility via lateral transduction exceeds that of classical mobile genetic elements. Nature Communications, 12, 6509. (doi: 10.1038/s41467-021-26004-5) (PMID:34750368) (PMCID:PMC8575950)

Humphrey, S. , San Millán, Á., Toll-Riera, M., Connolly, J., Flor-Duro, A., Chen, J., Ubeda, C., MacLean, R. C. and Penadés, J. R. (2021) Staphylococcal phages and pathogenicity islands drive plasmid evolution. Nature Communications, 12, 5845. (doi: 10.1038/s41467-021-26101-5) (PMID:34615859) (PMCID:PMC8494744)

Ciges-Tomas, J. R., Alite, C., Humphrey, S. , Donderis, J., Bowring, J. , Salvatella, X., Penadés, J. R. and Marina, A. (2019) The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature. Nature Communications, 10, 3676. (doi: 10.1038/s41467-019-11504-2) (PMID:31417084) (PMCID:PMC6695447)

Alite, C., Humphrey, S. , Donderis, J., Maiques, E., Ciges-Tomas, J. R., Penadés, J. R. and Marina, A. (2017) Dissecting the link between the enzymatic activity and the SaPI inducing capacity of the phage 80α dUTPase. Scientific Reports, 7, 11234. (doi: 10.1038/s41598-017-11234-9) (PMID:28894239) (PMCID:PMC5593958)

de Vries, S. P.W. et al. (2017) Genome-wide fitness analyses of the foodborne pathogen Campylobacter jejuni in in vitro and in vivo models. Scientific Reports, 7, 1251. (doi: 10.1038/s41598-017-01133-4) (PMID:28455506) (PMCID:PMC5430854)

Martínez-Rubio, R., Quiles-Puchalt, N., Martí, M., Humphrey, S. , Ram, G., Smyth, D., Chen, J., Novick, R. P. and Penadés, J. R. (2017) Phage inducible islands in the gram-positive cocci. ISME Journal, 11(4), pp. 1029-1042. (doi: 10.1038/ismej.2016.163) (PMID:27959343) (PMCID:PMC5363835)

Maiques, E., Quiles-Puchalt, N., Donderis, J., Ciges-Tomas, J. R., Alite, C., Bowring, J. Z. , Humphrey, S. , Penadés, J. R. and Marina, A. (2016) Another look at the mechanism involving trimeric dUTPases in Staphylococcus aureus pathogenicity island induction involves novel players in the party. Nucleic Acids Research, 44(11), pp. 5457-5469. (doi: 10.1093/nar/gkw317) (PMID:27112567) (PMCID:PMC4914113)

This list was generated on Sat Jan 28 07:05:53 2023 GMT.