Dr Sreenu Vattipally
- Research Scientist (Virology)
telephone:
0141 3304019
email:
Sreenu.Vattipally@glasgow.ac.uk
MRC-University of Glasgow Centre for Virus Research (CVR), Sir Michael Stoker Building, 464 Bearsden Road, Glasgow, G61 1QH
Biography
About Me
I am a bioinformatics research scientist at the MRC-University of Glasgow Centre for Virus Research (CVR). My work centres on employing advanced computational analysis to decode virus biology and evolution. I am deeply passionate about formulating novel algorithms and theoretical models that map the complexities of viral-host interactions. By bridging traditional bioinformatics with cutting-edge artificial intelligence, I aim to uncover the underlying mechanisms of viral pathogenesis and immune evasion.
Research Focus & Key Contributions
My research targets high-consequence pathogens, driving forward our understanding of viruses through genomic and structural analysis:
-
Pathogen Genomics: Leading whole-genome sequence assembly, annotation, and variant identification for SARS-CoV-2, Mpox, Hepatitis C Virus (HCV), and African Swine Fever Virus (ASFV).
-
STOP-HCV UK Consortium: Developed bespoke computational pipelines to analyse Next-Generation Sequencing (NGS) data, enabling the assembly of whole HCV genomes and the identification of resistance-associated substitutions.
-
Algorithmic Innovation: Created Tanoti, a novel NGS read mapping program specifically engineered to align and map highly variable reads from rapidly mutating viruses like HCV.
-
Host-Pathogen Interactions: Investigating the human immune factors involved in the spontaneous clearance of HCV, alongside predicting and modelling protein-protein interactions (PPI).
AI & Computational Expertise
I actively leverage Artificial Intelligence to push the boundaries of viral research and structural biology:
-
Structural Bioinformatics: Utilising AI for network analysis of residue interactions, protein modelling, and the computational design of protein binders engineered to block viral interactions.
-
Advanced Tool Development: Designing and deploying RAG-based AI agents, developing custom software solutions, and building web-based applications and robust databases to support broad scientific inquiry.
Academic Journey
-
Postdoctoral Fellowship: MRC Weatherall Institute of Molecular Medicine (WIMM), University of Oxford
-
PhD in Bioinformatics: University of Hyderabad, India
-
MSc in Microbiology & BSc in Biology: Osmania University, Hyderabad, India
See my publications on Google Scholar
Publications
2026
Immanuel, Omega Mathew, Fabiyi, Olaoluwa Tolulope, Issabekova, Zhanar Bakytzhanovna, Oshakbayev, Kuat P., Abuova, Gulzhan, Konysbekova, Aliya, Vattipally, Sreenu B. ORCID: https://orcid.org/0000-0001-6673-4697, Bajpai, Ram and Abidi, Syed Hani
(2026)
Prevalence of circulating hepatitis C virus genotypes and drug-resistant variants in former Soviet Union countries: a scoping review with genotype meta-analysis.
International Journal of Infectious Diseases,
(doi: 10.1016/j.ijid.2026.108871)
(PMID:42269919)
(Early Online Publication)
2025
Immanuel, Omega Mathew, Fabiyi, Olaoluwa Tolulope, Oshakbayev, Kuat P., Gulzhan, Abuova, Konysbekova, Aliya, Vattipally, Sreenu B. ORCID: https://orcid.org/0000-0001-6673-4697, Ali, Syed and Hani Abidi, Syed
(2025)
A bibliometric analysis of the HCV drug-resistant majority and minority variants.
International Journal of Environmental Research and Public Health, 22(11),
1670.
(doi: 10.3390/ijerph22111670)
Tate, M. et al. (2025) Clinical effectiveness, safety and viral mutagenicity of oral favipiravir for COVID-19: results from a community-based, open-label, randomised, phase III trial. Antimicrobial Agents and Chemotherapy, 69(8), e0005425. (doi: 10.1128/aac.00054-25) (PMID:40552814)
Wood, M. et al. (2025) Inherited chromosomally integrated human herpesvirus 6: regional variation in prevalence, association with angina, and identification of ancestral viral lineages in two large UK studies. Journal of Virology, 99(7), e0216024. (doi: 10.1128/jvi.02160-24) (PMID:40470957) (PMCID:PMC12282103)
Ashraf, S. et al. (2025) Uncovering the viral aetiology of undiagnosed acute febrile illness in Uganda using metagenomic sequencing. Nature Communications, 16, 2844. (doi: 10.1038/s41467-025-57696-8) (PMID:40122843) (PMCID:PMC11930947)
2024
Ahovègbé, L. et al. (2024) Hepatitis C virus diversity and treatment outcomes in Benin; a prospective cohort study. Lancet Microbe, 5(7), pp. 697-706. (doi: 10.1016/S2666-5247(24)00041-7) (PMID:38889738)
Spinard, E. et al. (2024) Near-complete genome sequences of multiple genotype 1 African swine fever virus isolates from 2016 to 2018 in Cameroon. Microbiology Resource Announcements, 13(4), e00978-23. (doi: 10.1128/mra.00978-23) (PMID:38477459) (PMCID:PMC11008206)
2023
Leggewie, M. et al. (2023) The Aedes aegypti RNA interference response against Zika virus in the context of co-infection with dengue and chikungunya viruses. PLoS Neglected Tropical Diseases, 17(7), e0011456. (doi: 10.1371/journal.pntd.0011456) (PMID:37440582) (PMCID:PMC10343070)
Jagtap, Swati V., Brink, Jorn, Frank, Svea C., Badusche, Marlis, Leggewie, Mayke, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Fuss, Janina, Schnettler, Esther and Altinli, Mine
(2023)
Agua Salud alphavirus infection, dissemination and transmission in Aedes aegypti mosquitoes.
Viruses, 15(5),
1113.
(doi: 10.3390/v15051113)
(PMID:37243199)
(PMCID:PMC10223791)
Alexander, A. J.T. et al. (2023) Characterisation of the antiviral RNA interference response to Toscana virus in sand fly cells. PLoS Pathogens, 19(3), e1011283. (doi: 10.1371/journal.ppat.1011283) (PMID:36996243) (PMCID:PMC10112792)
Altinli, Mine, Leggewie, Mayke, Schulze, Jonny, Gyanwali, Rashwita, Badusche, Marlis, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Fuss, Janina and Schnettler, Esther
(2023)
Antiviral RNAi response in Culex quinquefasciatus-derived HSU cells.
Viruses, 15(2),
436.
(doi: 10.3390/v15020436)
(PMID:36851650)
(PMCID:PMC9968050)
2022
Sugrue, E. et al. (2022) The apparent interferon resistance of transmitted HIV-1 is possibly a consequence of enhanced replicative fitness. PLoS Pathogens, 18(11), e1010973. (doi: 10.1371/journal.ppat.1010973) (PMID:36399512) (PMCID:PMC9718408)
Aranday-Cortes, E. et al. (2022) Real-world outcomes of direct-acting antiviral treatment and retreatment in United Kingdom–based patients infected with hepatitis C virus genotypes/subtypes endemic in Africa. Journal of Infectious Diseases, 226(6), pp. 995-1004. (doi: 10.1093/infdis/jiab110) (PMID:33668068) (PMCID:PMC9492310)
Xu, Ru, Rong, Xia, Aranday-Cortes, Elihu, Vattipally, Sreenu ORCID: https://orcid.org/0000-0001-6673-4697, Hughes, Joseph
ORCID: https://orcid.org/0000-0003-2556-2563, McLauchlan, John
ORCID: https://orcid.org/0000-0003-2217-9948 and Fu, Yongshui
(2022)
The transmission route and selection pressure in HCV subtype 3a and 3b Chinese infections: evolutionary kinetics and selective force analysis.
Viruses, 14(7),
1514.
(doi: 10.3390/v14071514)
(PMID:35891494)
(PMCID:PMC9324606)
Aggarwal, D. et al. (2022) Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission. Nature Communications, 13, 1012. (doi: 10.1038/s41467-022-28371-z) (PMID:35197443) (PMCID:PMC8866425)
Aggarwal, D. et al. (2022) Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission. Nature Communications, 13, 751. (doi: 10.1038/s41467-021-27942-w) (PMID:35136068) (PMCID:PMC8826310)
Gestuveo, R. et al. (2022) Mutational analysis of Aedes aegypti Dicer 2 provides insights into the biogenesis of antiviral exogenous small interfering RNAs. PLoS Pathogens, 18(1), e1010202. (doi: 10.1371/journal.ppat.1010202) (PMID:34990484) (PMCID:PMC8769306)
Twohig, K. A. et al. (2022) Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study. Lancet Infectious Diseases, 22(1), pp. 35-42. (doi: 10.1016/S1473-3099(21)00475-8) (PMID:34461056) (PMCID:PMC8397301)
2021
Vöhringer, H. S. et al. (2021) Genomic reconstruction of the SARS-CoV-2 epidemic in England. Nature, 600(7889), pp. 506-511. (doi: 10.1038/s41586-021-04069-y) (PMID:34649268) (PMCID:PMC8674138)
Falci Finardi, Nicole, Kim, HyeongJun, Hernandez, Lee Z., Russell, Matthew R. G., Ho, Catherine M-K, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Wenham, Hannah A., Merritt, Andy and Strang, Blair L.
(2021)
Identification and characterization of bisbenzimide compounds that inhibit human cytomegalovirus replication.
Journal of General Virology, 102(12),
001702.
(doi: 10.1099/jgv.0.001702)
(PMID:34882533)
Li, K. K. et al. (2021) Genetic epidemiology of SARS-CoV-2 transmission in renal dialysis units - a high risk community-hospital interface. Journal of Infection, 83(1), pp. 96-103. (doi: 10.1016/j.jinf.2021.04.020) (PMID:33895226) (PMCID:PMC8061788)
Scherer, C. et al. (2021) An Aedes aegypti-derived Ago2 knockout cell line to investigate arbovirus infections. Viruses, 13(6), 1066. (doi: 10.3390/v13061066) (PMID:34205194) (PMCID:PMC8227176)
Davis, C. A. et al. (2021) Hepatitis E virus: whole genome sequencing as a new tool for understanding HEV epidemiology and phenotypes. Journal of Clinical Virology, 139, 104738. (doi: 10.1016/j.jcv.2021.104738) (PMID:33933822)
Graham, M. S. et al. (2021) Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study. Lancet Public Health, 6(5), e335-e345. (doi: 10.1016/S2468-2667(21)00055-4)
Volz, E. et al. (2021) Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England. Nature, 593(7858), pp. 266-269. (doi: 10.1038/s41586-021-03470-x) (PMID:33767447)
Thomson, E. C. et al. (2021) Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity. Cell, 184(5), 1171-1187.e20. (doi: 10.1016/j.cell.2021.01.037) (PMID:33621484) (PMCID:PMC7843029)
Da Silva Filipe, A. et al. (2021) Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland. Nature Microbiology, 6(1), pp. 112-122. (doi: 10.1038/s41564-020-00838-z) (PMID:33349681)
2020
Gilbert, M. et al. (2020) Distemper, extinction and vaccination of the Amur tiger. Proceedings of the National Academy of Sciences of the United States of America, 117(50), pp. 31954-31962. (doi: 10.1073/pnas.2000153117) (PMID:33229566) (PMCID:PMC7749280)
Mokaya, J. et al. (2020) Evidence of tenofovir resistance in chronic hepatitis B virus (HBV) infection: An observational case series of South African adults. Journal of Clinical Virology, 129, 104548. (doi: 10.1016/j.jcv.2020.104548) (PMID:32663786) (PMCID:PMC7408481)
Alexander, A. J.T. et al. (2020) Development of a reverse genetics system for Toscana virus (lineage A). Viruses, 12(4), 411. (doi: 10.3390/v12040411)
2019
Jerome, H. et al. (2019) Metagenomic next-generation sequencing aids the diagnosis of viral infections in febrile returning travellers. Journal of Infection, 79(4), pp. 383-388. (doi: 10.1016/j.jinf.2019.08.003) (PMID:31398374) (PMCID:PMC6859916)
Ansari, M. A. et al. (2019) Interferon lambda 4 impacts the genetic diversity of hepatitis C virus. eLife, 8, e42463. (doi: 10.7554/eLife.42463) (PMID:31478835) (PMCID:PMC6721795)
Suárez, N. M. et al. (2019) Human cytomegalovirus genomes sequenced directly from clinical material: variation, multiple-strain infection, recombination and gene loss. Journal of Infectious Diseases, 220(5), pp. 781-791. (doi: 10.1093/infdis/jiz208) (PMID:31050742) (PMCID:PMC6667795)
Wignall-Fleming, Elizabeth B., Hughes, David J., Vattipally, Sreenu ORCID: https://orcid.org/0000-0001-6673-4697, Modha, Sejal
ORCID: https://orcid.org/0000-0002-8440-885X, Goodbourn, Steve, Davison, Andrew J.
ORCID: https://orcid.org/0000-0002-4991-9128 and Randall, Richard E.
(2019)
Analysis of paramyxovirus transcription and replication by high-throughput sequencing.
Journal of Virology, 93(17),
e00571-19.
(doi: 10.1128/JVI.00571-19)
(PMID:31189700)
(PMCID:PMC6694822)
Bamford, Connor, Wignall-Fleming, Elizabeth, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Randall, Richard, Duprex, Paul and Rima, Bertus
(2019)
Unusual, stable replicating viruses generated from mumps virus cDNA clones.
PLoS ONE, 14(7),
e0219168.
(doi: 10.1371/journal.pone.0219168)
(PMID:31276568)
(PMCID:PMC6611571)
Yen, Pei-Shi, Chen, Chun-Hong, Sreenu, Vattipally ORCID: https://orcid.org/0000-0001-6673-4697, Kohl, Alain
ORCID: https://orcid.org/0000-0002-1523-9458 and Failloux, Anna-Bella
(2019)
Assessing the potential interactions between cellular miRNA and arboviral genomic RNA in the Yellow Fever mosquito, Aedes aegypti.
Viruses, 11(6),
540.
(doi: 10.3390/v11060540)
(PMID:31185697)
(PMCID:PMC6631873)
Davis, C. et al. (2019) New highly diverse hepatitis C strains detected in sub‐Saharan Africa have unknown susceptibility to direct‐acting antiviral treatments. Hepatology, 69(4), pp. 1426-1441. (doi: 10.1002/hep.30342) (PMID:30387174) (PMCID:PMC6492010)
2018
Donald, Claire L. ORCID: https://orcid.org/0000-0002-4370-0707, Varjak, Margus
ORCID: https://orcid.org/0000-0003-2608-5148, Aguiar, Eric Roberto Guimarães Rocha, Marques, João T., Sreenu, Vatipally B.
ORCID: https://orcid.org/0000-0001-6673-4697, Schnettler, Esther and Kohl, Alain
ORCID: https://orcid.org/0000-0002-1523-9458
(2018)
Antiviral RNA interference activity in cells of the predatory mosquito, Toxorhynchites amboinensis.
Viruses, 10(12),
694.
(doi: 10.3390/v10120694)
(PMID:30563205)
(PMCID:PMC6316411)
Franzke, K. et al. (2018) Detection, infection dynamics and small RNA response against Culex Y virus in mosquito-derived cells. Journal of General Virology, 99, pp. 1739-1745. (doi: 10.1099/jgv.0.001173) (PMID:30394867)
Dunlop, J. I. et al. (2018) Development of reverse genetics systems and investigation of host response antagonism and reassortment potential for Cache Valley and Kairi viruses, two emerging orthobunyaviruses of the Americas. PLoS Neglected Tropical Diseases, 12(10), e0006884. (doi: 10.1371/journal.pntd.0006884) (PMID:30372452) (PMCID:PMC6245839)
Masembe, Charles ORCID: https://orcid.org/0000-0002-9581-0414, Sreenu, Vattipally B.
ORCID: https://orcid.org/0000-0001-6673-4697, Da Silva Filipe, Ana
ORCID: https://orcid.org/0000-0002-9442-2903, Wilkie, Gavin S., Ogweng, Peter, Mayega, Francis Johnson, Muwanika, Vincent B., Biek, Roman
ORCID: https://orcid.org/0000-0003-3471-5357, Palmarini, Massimo
ORCID: https://orcid.org/0000-0001-7007-4070 and Davison, Andrew J.
ORCID: https://orcid.org/0000-0002-4991-9128
(2018)
Genome sequences of five African swine fever virus genotype IX isolates from domestic pigs in Uganda.
Microbiology Resource Announcements, 7(13),
e01018-18.
(doi: 10.1128/mra.01018-18)
(PMID:30533685)
(PMCID:PMC6256554)
McNaughton, A.L., Sreenu, V.B. ORCID: https://orcid.org/0000-0001-6673-4697, Wilkie, G., Gunson, R., Templeton, K. and Leitch, E.C.M.
(2018)
Prevalence of mixed genotype hepatitis C virus infections in the UK as determined by genotype‐specific PCR and deep sequencing.
Journal of Viral Hepatitis, 25(5),
pp. 524-534.
(doi: 10.1111/jvh.12849)
(PMID:29274184)
(PMCID:PMC5947153)
da Silva Filipe, A. et al. (2018) Reply to: "Reply to: 'Response to DAA therapy in the NHS England Early Access Programme for rare HCV subtypes from low and middle income countries'". Journal of Hepatology, 68(4), pp. 864-866. (doi: 10.1016/j.jhep.2017.11.044) (PMID:29339112)
Lourenço-de-Oliveira, Ricardo, Marques, João T., Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Nten, Célestine Atyame, Guimarães Rocha Aguiarr, Eric Roberto, Varjak, Margus
ORCID: https://orcid.org/0000-0003-2608-5148, Kohl, Alain
ORCID: https://orcid.org/0000-0002-1523-9458 and Failloux, Anna-Bella
(2018)
Culex quinquefasciatus mosquitoes do not support replication of Zika virus.
Journal of General Virology, 99,
pp. 258-264.
(doi: 10.1099/jgv.0.000949)
(PMID:29076805)
(PMCID:PMC5882084)
2017
da Silva Filipe, A. et al. (2017) Response to DAA therapy in the NHS England early access programme for rare HCV subtypes from low and middle income countries. Journal of Hepatology, 67(6), pp. 1348-1350. (doi: 10.1016/j.jhep.2017.06.035) (PMID:28789880)
Varjak, Margus ORCID: https://orcid.org/0000-0003-2608-5148, Donald, Claire L.
ORCID: https://orcid.org/0000-0002-4370-0707, Mottram, Timothy J., Sreenu, Vattipally B.
ORCID: https://orcid.org/0000-0001-6673-4697, Merits, Andres, Maringer, Kevin, Schnettler, Esther and Kohl, Alain
ORCID: https://orcid.org/0000-0002-1523-9458
(2017)
Characterization of the Zika virus induced small RNA response in Aedes aegypti cells.
PLoS Neglected Tropical Diseases, 11(10),
e0006010.
(doi: 10.1371/journal.pntd.0006010)
(PMID:29040304)
(PMCID:PMC5667879)
Varjak, M. et al. (2017) Aedes aegypti Piwi4 is a noncanonical PIWI protein involved in antiviral responses. mSphere, 2(3), 00144-17. (doi: 10.1128/mSphere.00144-17) (PMID:28497119) (PMCID:PMC5415634)
2016
Schnettler, Esther, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Mottram, Timothy and McFarlane, Melanie
ORCID: https://orcid.org/0000-0002-8392-2291
(2016)
Wolbachia restricts insect specific flavivirus infection in Aedes aegypti cells.
Journal of General Virology, 97(11),
pp. 3024-3029.
(doi: 10.1099/jgv.0.000617)
(PMID:27692043)
(PMCID:PMC5120408)
Thomson, E. et al. (2016) Comparison of next-generation sequencing technologies for the comprehensive assessment of full-length hepatitis C viral genomes. Journal of Clinical Microbiology, 54(10), pp. 2470-2484. (doi: 10.1128/JCM.00330-16) (PMID:27385709) (PMCID:PMC5035407)
Polachek, William S., Moshrif, Hanan F., Franti, Michael, Coen, Donald M., Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697 and Strang, Blair L.
(2016)
High-throughput small interfering RNA screening identifies phosphatidylinositol 3-kinase class II alpha as important for production of human cytomegalovirus virions.
Journal of Virology, 90(18),
pp. 8360-8371.
(doi: 10.1128/JVI.01134-16)
(PMID:27412598)
Jacobs, M. et al. (2016) Late Ebola virus relapse causing meningoencephalitis: a case report. Lancet, 388(10043), pp. 498-503. (doi: 10.1016/S0140-6736(16)30386-5) (PMID:27209148) (PMCID:PMC4967715)
Orton, R.J. ORCID: https://orcid.org/0000-0002-3389-4325, Gu, Q.
ORCID: https://orcid.org/0000-0002-1201-6734, Hughes, J.
ORCID: https://orcid.org/0000-0003-2556-2563, Maabar, M., Modha, S.
ORCID: https://orcid.org/0000-0002-8440-885X, Vattipally, Sreenu
ORCID: https://orcid.org/0000-0001-6673-4697, Wilkie, G.S. and Davison, A.
ORCID: https://orcid.org/0000-0002-4991-9128
(2016)
Bioinformatics tools for analysing viral genomic data.
Revue scientifique et technique (International Office of Epizootics), 35(1),
pp. 241-285.
(doi: 10.20506/rst.35.1.2432)
(PMID:27217183)
2015
Jerome, Hanna, Vattipally, Sreenu B. ORCID: https://orcid.org/0000-0001-6673-4697 and Thomson, Emma C.
ORCID: https://orcid.org/0000-0003-1482-0889
(2015)
Can we identify potential viral zoonoses before they cross the species barrier?
Microbiology Today, 42(4),
pp. 150-153.
Chang, C.-H. et al. (2015) HIV-infected sex workers with beneficial HLA-variants are potential hubs for selection of HIV-1 recombinants that may affect disease progression. Scientific Reports, 5, 11253. (doi: 10.1038/srep11253) (PMID:26082240) (PMCID:PMC4469978)
Gaunt, Eleanor, Harvala, Heli, Osterback, Riikka, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Thomson, Emma
ORCID: https://orcid.org/0000-0003-1482-0889, Waris, Matti and Simmonds, Peter
(2015)
Genetic characterization of human coxsackievirus A6 variants associated with atypical hand, foot and mouth disease: a potential role of recombination in emergence and pathogenicity.
Journal of General Virology, 96(5),
pp. 1067-1079.
(doi: 10.1099/vir.0.000062)
(PMID:25614593)
(PMCID:PMC4631059)
2014
Tenzer, S. et al. (2014) HIV-1 adaptation to antigen processing results in population-level immune evasion and affects subtype diversification. Cell Reports, 7(2), pp. 448-463. (doi: 10.1016/j.celrep.2014.03.031)
2013
Leggewie, M., Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Abdelrahman, T., Leitch, E. Carol, Wilkie, G., Klymenko, T., Muir, D., Thursz, M., Main, J. and Thomson, E.C.
ORCID: https://orcid.org/0000-0003-1482-0889
(2013)
Natural NS3 resistance polymorphisms occur frequently prior to treatment in HIV-positive patients with acute hepatitis C.
AIDS, 27(15),
pp. 2485-2488.
(doi: 10.1097/QAD.0b013e328363b1f9)
(PMID:23770494)
2011
Carmo, Alexandre M. and Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697
(2011)
A systematic and thorough search for domains of the scavenger receptor cysteine-rich Group-B family in the human genome.
In: Mahdavi, Mahmood A. (ed.)
Bioinformatics: Trends and Methodologies.
IntechOpen.
ISBN 9789533072821
(doi: 10.5772/19462)
2009
Gonçalves, C. M. et al. (2009) Molecular cloning and analysis of SSc5D, a new member of the scavenger receptor cysteine-rich superfamily. Molecular Immunology, 46(13), pp. 2585-2596. (doi: 10.1016/j.molimm.2009.05.006) (PMID:19535143)
2008
Abidi, S. Hussain I., Dong, Tao, Vuong, Mai T., Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Rowland-Jones, Sarah L., Evans, Edward J. and Davis, Simon J.
(2008)
Differential remodeling of a T-cell transcriptome following CD8- versus CD3-induced signaling.
Cell Research, 18(6),
pp. 641-648.
(doi: 10.1038/cr.2008.56)
(PMID:18475290)
(PMCID:PMC2731849)
2007
Hene, Lawrence, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Vuong, Mai T., Abidi, S. Hussain I., Sutton, Julian K., Rowland-Jones, Sarah L., Davis, Simon J. and Evans, Edward J.
(2007)
Deep analysis of cellular transcriptomes – LongSAGE versus classic MPSS.
BMC Genomics, 8(1),
333.
(doi: 10.1186/1471-2164-8-333)
(PMID:17892551)
(PMCID:PMC2104538)
Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Kumar, Pankaj, Nagaraju, Javaregowda and Nagarajaram, Hampapathalu A.
(2007)
Simple sequence repeats in mycobacterial genomes.
Journal of Biosciences, 32(1),
pp. 3-15.
(doi: 10.1007/s12038-007-0002-7)
(PMID:17426376)
2006
Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Kumar, Pankaj, Nagaraju, Javaregowda and Nagarajaram, Hampapthalu A.
(2006)
Microsatellite polymorphism across the M. tuberculosis and M. bovis genomes: Implications on genome evolution and plasticity.
BMC Genomics, 7(1),
78.
(doi: 10.1186/1471-2164-7-78)
(PMID:16603092)
(PMCID:PMC1501019)
2005
Prasad, M.D. et al. (2005) SilkSatDb: a microsatellite database of the silkworm, Bombyx mori. Nucleic Acids Research, 33(Suppl1), D403-D406. (doi: 10.1093/nar/gki099) (PMID:15608226) (PMCID:PMC540053)
Gundu, R.K., Swamynathan, S., Sreenu, V.B. ORCID: https://orcid.org/0000-0001-6673-4697, Pavan, N., Acharya, S. and Nagarajaram, H.A.
(2005)
Frontiers in bioinformatics research: the biodiversity issues.
In: Tandon, Pramod, Sharma, Manju and Swarup, Renu (eds.)
Biodiversity: Status and Prospects.
Narosa Publishing House: New Dehli.
ISBN 9788173196768
2003
Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Alevoor, Vishwanath, Javaregowda, Nagaraju and Nagarajaram, Hampapathalu A.
(2003)
MICdb: database of prokaryotic microsatellites.
Nucleic Acids Research, 31(1),
pp. 106-108.
(doi: 10.1093/nar/gkg002)
(PMID:12519959)
(PMCID:PMC165449)
Ranjitkumar, G., Pavan, M. Narendar, Bose, B., Swaminathan, S., Geetha, T., Prashanthi, P., Prasad, B. Phani, Sreenu, V.B. ORCID: https://orcid.org/0000-0001-6673-4697, Achary, M. Sridhar and Nagarajaram, H.A.
(2003)
EMBnet India Node (EIN) at the Centre for DNA Fingerprinting and Diagnostics: serving the Indian sub-continent in bioinformatics.
Bioinformatics India, 1(2),
pp. 67-77.
Sreenu, V.B. ORCID: https://orcid.org/0000-0001-6673-4697, Ranjitkumar, G., Swaminathan, S., Priya, S., Bose, B., Pavan, M.N., Thanu, G., Nagaraju, J. and Nagarajaram, H.A.
(2003)
MICAS: a fully automated web server for microsatellite extraction and analysis from prokaryote and viral genomic sequences.
Applied Bioinformatics, 2(3),
pp. 165-168.
(PMID:15130803)
2002
Kamal, Ahmed, Ramesh, G., Laxman, N., Ramulu, P., Srinivas, O., Neelima, K., Kondapi, Anand K., Sreenu, V.B. ORCID: https://orcid.org/0000-0001-6673-4697 and Nagarajaram, H.A.
(2002)
Design, synthesis, and evaluation of new noncross-linking pyrrolobenzodiazepine dimers with efficient DNA binding ability and potent antitumor activity.
Journal of Medicinal Chemistry, 45(21),
pp. 4679-4688.
(doi: 10.1021/jm020124h)
(PMID:12361394)
Articles
Immanuel, Omega Mathew, Fabiyi, Olaoluwa Tolulope, Issabekova, Zhanar Bakytzhanovna, Oshakbayev, Kuat P., Abuova, Gulzhan, Konysbekova, Aliya, Vattipally, Sreenu B. ORCID: https://orcid.org/0000-0001-6673-4697, Bajpai, Ram and Abidi, Syed Hani
(2026)
Prevalence of circulating hepatitis C virus genotypes and drug-resistant variants in former Soviet Union countries: a scoping review with genotype meta-analysis.
International Journal of Infectious Diseases,
(doi: 10.1016/j.ijid.2026.108871)
(PMID:42269919)
(Early Online Publication)
Immanuel, Omega Mathew, Fabiyi, Olaoluwa Tolulope, Oshakbayev, Kuat P., Gulzhan, Abuova, Konysbekova, Aliya, Vattipally, Sreenu B. ORCID: https://orcid.org/0000-0001-6673-4697, Ali, Syed and Hani Abidi, Syed
(2025)
A bibliometric analysis of the HCV drug-resistant majority and minority variants.
International Journal of Environmental Research and Public Health, 22(11),
1670.
(doi: 10.3390/ijerph22111670)
Tate, M. et al. (2025) Clinical effectiveness, safety and viral mutagenicity of oral favipiravir for COVID-19: results from a community-based, open-label, randomised, phase III trial. Antimicrobial Agents and Chemotherapy, 69(8), e0005425. (doi: 10.1128/aac.00054-25) (PMID:40552814)
Wood, M. et al. (2025) Inherited chromosomally integrated human herpesvirus 6: regional variation in prevalence, association with angina, and identification of ancestral viral lineages in two large UK studies. Journal of Virology, 99(7), e0216024. (doi: 10.1128/jvi.02160-24) (PMID:40470957) (PMCID:PMC12282103)
Ashraf, S. et al. (2025) Uncovering the viral aetiology of undiagnosed acute febrile illness in Uganda using metagenomic sequencing. Nature Communications, 16, 2844. (doi: 10.1038/s41467-025-57696-8) (PMID:40122843) (PMCID:PMC11930947)
Ahovègbé, L. et al. (2024) Hepatitis C virus diversity and treatment outcomes in Benin; a prospective cohort study. Lancet Microbe, 5(7), pp. 697-706. (doi: 10.1016/S2666-5247(24)00041-7) (PMID:38889738)
Spinard, E. et al. (2024) Near-complete genome sequences of multiple genotype 1 African swine fever virus isolates from 2016 to 2018 in Cameroon. Microbiology Resource Announcements, 13(4), e00978-23. (doi: 10.1128/mra.00978-23) (PMID:38477459) (PMCID:PMC11008206)
Leggewie, M. et al. (2023) The Aedes aegypti RNA interference response against Zika virus in the context of co-infection with dengue and chikungunya viruses. PLoS Neglected Tropical Diseases, 17(7), e0011456. (doi: 10.1371/journal.pntd.0011456) (PMID:37440582) (PMCID:PMC10343070)
Jagtap, Swati V., Brink, Jorn, Frank, Svea C., Badusche, Marlis, Leggewie, Mayke, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Fuss, Janina, Schnettler, Esther and Altinli, Mine
(2023)
Agua Salud alphavirus infection, dissemination and transmission in Aedes aegypti mosquitoes.
Viruses, 15(5),
1113.
(doi: 10.3390/v15051113)
(PMID:37243199)
(PMCID:PMC10223791)
Alexander, A. J.T. et al. (2023) Characterisation of the antiviral RNA interference response to Toscana virus in sand fly cells. PLoS Pathogens, 19(3), e1011283. (doi: 10.1371/journal.ppat.1011283) (PMID:36996243) (PMCID:PMC10112792)
Altinli, Mine, Leggewie, Mayke, Schulze, Jonny, Gyanwali, Rashwita, Badusche, Marlis, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Fuss, Janina and Schnettler, Esther
(2023)
Antiviral RNAi response in Culex quinquefasciatus-derived HSU cells.
Viruses, 15(2),
436.
(doi: 10.3390/v15020436)
(PMID:36851650)
(PMCID:PMC9968050)
Sugrue, E. et al. (2022) The apparent interferon resistance of transmitted HIV-1 is possibly a consequence of enhanced replicative fitness. PLoS Pathogens, 18(11), e1010973. (doi: 10.1371/journal.ppat.1010973) (PMID:36399512) (PMCID:PMC9718408)
Aranday-Cortes, E. et al. (2022) Real-world outcomes of direct-acting antiviral treatment and retreatment in United Kingdom–based patients infected with hepatitis C virus genotypes/subtypes endemic in Africa. Journal of Infectious Diseases, 226(6), pp. 995-1004. (doi: 10.1093/infdis/jiab110) (PMID:33668068) (PMCID:PMC9492310)
Xu, Ru, Rong, Xia, Aranday-Cortes, Elihu, Vattipally, Sreenu ORCID: https://orcid.org/0000-0001-6673-4697, Hughes, Joseph
ORCID: https://orcid.org/0000-0003-2556-2563, McLauchlan, John
ORCID: https://orcid.org/0000-0003-2217-9948 and Fu, Yongshui
(2022)
The transmission route and selection pressure in HCV subtype 3a and 3b Chinese infections: evolutionary kinetics and selective force analysis.
Viruses, 14(7),
1514.
(doi: 10.3390/v14071514)
(PMID:35891494)
(PMCID:PMC9324606)
Aggarwal, D. et al. (2022) Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission. Nature Communications, 13, 1012. (doi: 10.1038/s41467-022-28371-z) (PMID:35197443) (PMCID:PMC8866425)
Aggarwal, D. et al. (2022) Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission. Nature Communications, 13, 751. (doi: 10.1038/s41467-021-27942-w) (PMID:35136068) (PMCID:PMC8826310)
Gestuveo, R. et al. (2022) Mutational analysis of Aedes aegypti Dicer 2 provides insights into the biogenesis of antiviral exogenous small interfering RNAs. PLoS Pathogens, 18(1), e1010202. (doi: 10.1371/journal.ppat.1010202) (PMID:34990484) (PMCID:PMC8769306)
Twohig, K. A. et al. (2022) Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study. Lancet Infectious Diseases, 22(1), pp. 35-42. (doi: 10.1016/S1473-3099(21)00475-8) (PMID:34461056) (PMCID:PMC8397301)
Vöhringer, H. S. et al. (2021) Genomic reconstruction of the SARS-CoV-2 epidemic in England. Nature, 600(7889), pp. 506-511. (doi: 10.1038/s41586-021-04069-y) (PMID:34649268) (PMCID:PMC8674138)
Falci Finardi, Nicole, Kim, HyeongJun, Hernandez, Lee Z., Russell, Matthew R. G., Ho, Catherine M-K, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Wenham, Hannah A., Merritt, Andy and Strang, Blair L.
(2021)
Identification and characterization of bisbenzimide compounds that inhibit human cytomegalovirus replication.
Journal of General Virology, 102(12),
001702.
(doi: 10.1099/jgv.0.001702)
(PMID:34882533)
Li, K. K. et al. (2021) Genetic epidemiology of SARS-CoV-2 transmission in renal dialysis units - a high risk community-hospital interface. Journal of Infection, 83(1), pp. 96-103. (doi: 10.1016/j.jinf.2021.04.020) (PMID:33895226) (PMCID:PMC8061788)
Scherer, C. et al. (2021) An Aedes aegypti-derived Ago2 knockout cell line to investigate arbovirus infections. Viruses, 13(6), 1066. (doi: 10.3390/v13061066) (PMID:34205194) (PMCID:PMC8227176)
Davis, C. A. et al. (2021) Hepatitis E virus: whole genome sequencing as a new tool for understanding HEV epidemiology and phenotypes. Journal of Clinical Virology, 139, 104738. (doi: 10.1016/j.jcv.2021.104738) (PMID:33933822)
Graham, M. S. et al. (2021) Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study. Lancet Public Health, 6(5), e335-e345. (doi: 10.1016/S2468-2667(21)00055-4)
Volz, E. et al. (2021) Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England. Nature, 593(7858), pp. 266-269. (doi: 10.1038/s41586-021-03470-x) (PMID:33767447)
Thomson, E. C. et al. (2021) Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity. Cell, 184(5), 1171-1187.e20. (doi: 10.1016/j.cell.2021.01.037) (PMID:33621484) (PMCID:PMC7843029)
Da Silva Filipe, A. et al. (2021) Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland. Nature Microbiology, 6(1), pp. 112-122. (doi: 10.1038/s41564-020-00838-z) (PMID:33349681)
Gilbert, M. et al. (2020) Distemper, extinction and vaccination of the Amur tiger. Proceedings of the National Academy of Sciences of the United States of America, 117(50), pp. 31954-31962. (doi: 10.1073/pnas.2000153117) (PMID:33229566) (PMCID:PMC7749280)
Mokaya, J. et al. (2020) Evidence of tenofovir resistance in chronic hepatitis B virus (HBV) infection: An observational case series of South African adults. Journal of Clinical Virology, 129, 104548. (doi: 10.1016/j.jcv.2020.104548) (PMID:32663786) (PMCID:PMC7408481)
Alexander, A. J.T. et al. (2020) Development of a reverse genetics system for Toscana virus (lineage A). Viruses, 12(4), 411. (doi: 10.3390/v12040411)
Jerome, H. et al. (2019) Metagenomic next-generation sequencing aids the diagnosis of viral infections in febrile returning travellers. Journal of Infection, 79(4), pp. 383-388. (doi: 10.1016/j.jinf.2019.08.003) (PMID:31398374) (PMCID:PMC6859916)
Ansari, M. A. et al. (2019) Interferon lambda 4 impacts the genetic diversity of hepatitis C virus. eLife, 8, e42463. (doi: 10.7554/eLife.42463) (PMID:31478835) (PMCID:PMC6721795)
Suárez, N. M. et al. (2019) Human cytomegalovirus genomes sequenced directly from clinical material: variation, multiple-strain infection, recombination and gene loss. Journal of Infectious Diseases, 220(5), pp. 781-791. (doi: 10.1093/infdis/jiz208) (PMID:31050742) (PMCID:PMC6667795)
Wignall-Fleming, Elizabeth B., Hughes, David J., Vattipally, Sreenu ORCID: https://orcid.org/0000-0001-6673-4697, Modha, Sejal
ORCID: https://orcid.org/0000-0002-8440-885X, Goodbourn, Steve, Davison, Andrew J.
ORCID: https://orcid.org/0000-0002-4991-9128 and Randall, Richard E.
(2019)
Analysis of paramyxovirus transcription and replication by high-throughput sequencing.
Journal of Virology, 93(17),
e00571-19.
(doi: 10.1128/JVI.00571-19)
(PMID:31189700)
(PMCID:PMC6694822)
Bamford, Connor, Wignall-Fleming, Elizabeth, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Randall, Richard, Duprex, Paul and Rima, Bertus
(2019)
Unusual, stable replicating viruses generated from mumps virus cDNA clones.
PLoS ONE, 14(7),
e0219168.
(doi: 10.1371/journal.pone.0219168)
(PMID:31276568)
(PMCID:PMC6611571)
Yen, Pei-Shi, Chen, Chun-Hong, Sreenu, Vattipally ORCID: https://orcid.org/0000-0001-6673-4697, Kohl, Alain
ORCID: https://orcid.org/0000-0002-1523-9458 and Failloux, Anna-Bella
(2019)
Assessing the potential interactions between cellular miRNA and arboviral genomic RNA in the Yellow Fever mosquito, Aedes aegypti.
Viruses, 11(6),
540.
(doi: 10.3390/v11060540)
(PMID:31185697)
(PMCID:PMC6631873)
Davis, C. et al. (2019) New highly diverse hepatitis C strains detected in sub‐Saharan Africa have unknown susceptibility to direct‐acting antiviral treatments. Hepatology, 69(4), pp. 1426-1441. (doi: 10.1002/hep.30342) (PMID:30387174) (PMCID:PMC6492010)
Donald, Claire L. ORCID: https://orcid.org/0000-0002-4370-0707, Varjak, Margus
ORCID: https://orcid.org/0000-0003-2608-5148, Aguiar, Eric Roberto Guimarães Rocha, Marques, João T., Sreenu, Vatipally B.
ORCID: https://orcid.org/0000-0001-6673-4697, Schnettler, Esther and Kohl, Alain
ORCID: https://orcid.org/0000-0002-1523-9458
(2018)
Antiviral RNA interference activity in cells of the predatory mosquito, Toxorhynchites amboinensis.
Viruses, 10(12),
694.
(doi: 10.3390/v10120694)
(PMID:30563205)
(PMCID:PMC6316411)
Franzke, K. et al. (2018) Detection, infection dynamics and small RNA response against Culex Y virus in mosquito-derived cells. Journal of General Virology, 99, pp. 1739-1745. (doi: 10.1099/jgv.0.001173) (PMID:30394867)
Dunlop, J. I. et al. (2018) Development of reverse genetics systems and investigation of host response antagonism and reassortment potential for Cache Valley and Kairi viruses, two emerging orthobunyaviruses of the Americas. PLoS Neglected Tropical Diseases, 12(10), e0006884. (doi: 10.1371/journal.pntd.0006884) (PMID:30372452) (PMCID:PMC6245839)
Masembe, Charles ORCID: https://orcid.org/0000-0002-9581-0414, Sreenu, Vattipally B.
ORCID: https://orcid.org/0000-0001-6673-4697, Da Silva Filipe, Ana
ORCID: https://orcid.org/0000-0002-9442-2903, Wilkie, Gavin S., Ogweng, Peter, Mayega, Francis Johnson, Muwanika, Vincent B., Biek, Roman
ORCID: https://orcid.org/0000-0003-3471-5357, Palmarini, Massimo
ORCID: https://orcid.org/0000-0001-7007-4070 and Davison, Andrew J.
ORCID: https://orcid.org/0000-0002-4991-9128
(2018)
Genome sequences of five African swine fever virus genotype IX isolates from domestic pigs in Uganda.
Microbiology Resource Announcements, 7(13),
e01018-18.
(doi: 10.1128/mra.01018-18)
(PMID:30533685)
(PMCID:PMC6256554)
McNaughton, A.L., Sreenu, V.B. ORCID: https://orcid.org/0000-0001-6673-4697, Wilkie, G., Gunson, R., Templeton, K. and Leitch, E.C.M.
(2018)
Prevalence of mixed genotype hepatitis C virus infections in the UK as determined by genotype‐specific PCR and deep sequencing.
Journal of Viral Hepatitis, 25(5),
pp. 524-534.
(doi: 10.1111/jvh.12849)
(PMID:29274184)
(PMCID:PMC5947153)
da Silva Filipe, A. et al. (2018) Reply to: "Reply to: 'Response to DAA therapy in the NHS England Early Access Programme for rare HCV subtypes from low and middle income countries'". Journal of Hepatology, 68(4), pp. 864-866. (doi: 10.1016/j.jhep.2017.11.044) (PMID:29339112)
Lourenço-de-Oliveira, Ricardo, Marques, João T., Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Nten, Célestine Atyame, Guimarães Rocha Aguiarr, Eric Roberto, Varjak, Margus
ORCID: https://orcid.org/0000-0003-2608-5148, Kohl, Alain
ORCID: https://orcid.org/0000-0002-1523-9458 and Failloux, Anna-Bella
(2018)
Culex quinquefasciatus mosquitoes do not support replication of Zika virus.
Journal of General Virology, 99,
pp. 258-264.
(doi: 10.1099/jgv.0.000949)
(PMID:29076805)
(PMCID:PMC5882084)
da Silva Filipe, A. et al. (2017) Response to DAA therapy in the NHS England early access programme for rare HCV subtypes from low and middle income countries. Journal of Hepatology, 67(6), pp. 1348-1350. (doi: 10.1016/j.jhep.2017.06.035) (PMID:28789880)
Varjak, Margus ORCID: https://orcid.org/0000-0003-2608-5148, Donald, Claire L.
ORCID: https://orcid.org/0000-0002-4370-0707, Mottram, Timothy J., Sreenu, Vattipally B.
ORCID: https://orcid.org/0000-0001-6673-4697, Merits, Andres, Maringer, Kevin, Schnettler, Esther and Kohl, Alain
ORCID: https://orcid.org/0000-0002-1523-9458
(2017)
Characterization of the Zika virus induced small RNA response in Aedes aegypti cells.
PLoS Neglected Tropical Diseases, 11(10),
e0006010.
(doi: 10.1371/journal.pntd.0006010)
(PMID:29040304)
(PMCID:PMC5667879)
Varjak, M. et al. (2017) Aedes aegypti Piwi4 is a noncanonical PIWI protein involved in antiviral responses. mSphere, 2(3), 00144-17. (doi: 10.1128/mSphere.00144-17) (PMID:28497119) (PMCID:PMC5415634)
Schnettler, Esther, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Mottram, Timothy and McFarlane, Melanie
ORCID: https://orcid.org/0000-0002-8392-2291
(2016)
Wolbachia restricts insect specific flavivirus infection in Aedes aegypti cells.
Journal of General Virology, 97(11),
pp. 3024-3029.
(doi: 10.1099/jgv.0.000617)
(PMID:27692043)
(PMCID:PMC5120408)
Thomson, E. et al. (2016) Comparison of next-generation sequencing technologies for the comprehensive assessment of full-length hepatitis C viral genomes. Journal of Clinical Microbiology, 54(10), pp. 2470-2484. (doi: 10.1128/JCM.00330-16) (PMID:27385709) (PMCID:PMC5035407)
Polachek, William S., Moshrif, Hanan F., Franti, Michael, Coen, Donald M., Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697 and Strang, Blair L.
(2016)
High-throughput small interfering RNA screening identifies phosphatidylinositol 3-kinase class II alpha as important for production of human cytomegalovirus virions.
Journal of Virology, 90(18),
pp. 8360-8371.
(doi: 10.1128/JVI.01134-16)
(PMID:27412598)
Jacobs, M. et al. (2016) Late Ebola virus relapse causing meningoencephalitis: a case report. Lancet, 388(10043), pp. 498-503. (doi: 10.1016/S0140-6736(16)30386-5) (PMID:27209148) (PMCID:PMC4967715)
Orton, R.J. ORCID: https://orcid.org/0000-0002-3389-4325, Gu, Q.
ORCID: https://orcid.org/0000-0002-1201-6734, Hughes, J.
ORCID: https://orcid.org/0000-0003-2556-2563, Maabar, M., Modha, S.
ORCID: https://orcid.org/0000-0002-8440-885X, Vattipally, Sreenu
ORCID: https://orcid.org/0000-0001-6673-4697, Wilkie, G.S. and Davison, A.
ORCID: https://orcid.org/0000-0002-4991-9128
(2016)
Bioinformatics tools for analysing viral genomic data.
Revue scientifique et technique (International Office of Epizootics), 35(1),
pp. 241-285.
(doi: 10.20506/rst.35.1.2432)
(PMID:27217183)
Jerome, Hanna, Vattipally, Sreenu B. ORCID: https://orcid.org/0000-0001-6673-4697 and Thomson, Emma C.
ORCID: https://orcid.org/0000-0003-1482-0889
(2015)
Can we identify potential viral zoonoses before they cross the species barrier?
Microbiology Today, 42(4),
pp. 150-153.
Chang, C.-H. et al. (2015) HIV-infected sex workers with beneficial HLA-variants are potential hubs for selection of HIV-1 recombinants that may affect disease progression. Scientific Reports, 5, 11253. (doi: 10.1038/srep11253) (PMID:26082240) (PMCID:PMC4469978)
Gaunt, Eleanor, Harvala, Heli, Osterback, Riikka, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Thomson, Emma
ORCID: https://orcid.org/0000-0003-1482-0889, Waris, Matti and Simmonds, Peter
(2015)
Genetic characterization of human coxsackievirus A6 variants associated with atypical hand, foot and mouth disease: a potential role of recombination in emergence and pathogenicity.
Journal of General Virology, 96(5),
pp. 1067-1079.
(doi: 10.1099/vir.0.000062)
(PMID:25614593)
(PMCID:PMC4631059)
Tenzer, S. et al. (2014) HIV-1 adaptation to antigen processing results in population-level immune evasion and affects subtype diversification. Cell Reports, 7(2), pp. 448-463. (doi: 10.1016/j.celrep.2014.03.031)
Leggewie, M., Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Abdelrahman, T., Leitch, E. Carol, Wilkie, G., Klymenko, T., Muir, D., Thursz, M., Main, J. and Thomson, E.C.
ORCID: https://orcid.org/0000-0003-1482-0889
(2013)
Natural NS3 resistance polymorphisms occur frequently prior to treatment in HIV-positive patients with acute hepatitis C.
AIDS, 27(15),
pp. 2485-2488.
(doi: 10.1097/QAD.0b013e328363b1f9)
(PMID:23770494)
Gonçalves, C. M. et al. (2009) Molecular cloning and analysis of SSc5D, a new member of the scavenger receptor cysteine-rich superfamily. Molecular Immunology, 46(13), pp. 2585-2596. (doi: 10.1016/j.molimm.2009.05.006) (PMID:19535143)
Abidi, S. Hussain I., Dong, Tao, Vuong, Mai T., Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Rowland-Jones, Sarah L., Evans, Edward J. and Davis, Simon J.
(2008)
Differential remodeling of a T-cell transcriptome following CD8- versus CD3-induced signaling.
Cell Research, 18(6),
pp. 641-648.
(doi: 10.1038/cr.2008.56)
(PMID:18475290)
(PMCID:PMC2731849)
Hene, Lawrence, Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Vuong, Mai T., Abidi, S. Hussain I., Sutton, Julian K., Rowland-Jones, Sarah L., Davis, Simon J. and Evans, Edward J.
(2007)
Deep analysis of cellular transcriptomes – LongSAGE versus classic MPSS.
BMC Genomics, 8(1),
333.
(doi: 10.1186/1471-2164-8-333)
(PMID:17892551)
(PMCID:PMC2104538)
Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Kumar, Pankaj, Nagaraju, Javaregowda and Nagarajaram, Hampapathalu A.
(2007)
Simple sequence repeats in mycobacterial genomes.
Journal of Biosciences, 32(1),
pp. 3-15.
(doi: 10.1007/s12038-007-0002-7)
(PMID:17426376)
Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Kumar, Pankaj, Nagaraju, Javaregowda and Nagarajaram, Hampapthalu A.
(2006)
Microsatellite polymorphism across the M. tuberculosis and M. bovis genomes: Implications on genome evolution and plasticity.
BMC Genomics, 7(1),
78.
(doi: 10.1186/1471-2164-7-78)
(PMID:16603092)
(PMCID:PMC1501019)
Prasad, M.D. et al. (2005) SilkSatDb: a microsatellite database of the silkworm, Bombyx mori. Nucleic Acids Research, 33(Suppl1), D403-D406. (doi: 10.1093/nar/gki099) (PMID:15608226) (PMCID:PMC540053)
Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697, Alevoor, Vishwanath, Javaregowda, Nagaraju and Nagarajaram, Hampapathalu A.
(2003)
MICdb: database of prokaryotic microsatellites.
Nucleic Acids Research, 31(1),
pp. 106-108.
(doi: 10.1093/nar/gkg002)
(PMID:12519959)
(PMCID:PMC165449)
Ranjitkumar, G., Pavan, M. Narendar, Bose, B., Swaminathan, S., Geetha, T., Prashanthi, P., Prasad, B. Phani, Sreenu, V.B. ORCID: https://orcid.org/0000-0001-6673-4697, Achary, M. Sridhar and Nagarajaram, H.A.
(2003)
EMBnet India Node (EIN) at the Centre for DNA Fingerprinting and Diagnostics: serving the Indian sub-continent in bioinformatics.
Bioinformatics India, 1(2),
pp. 67-77.
Sreenu, V.B. ORCID: https://orcid.org/0000-0001-6673-4697, Ranjitkumar, G., Swaminathan, S., Priya, S., Bose, B., Pavan, M.N., Thanu, G., Nagaraju, J. and Nagarajaram, H.A.
(2003)
MICAS: a fully automated web server for microsatellite extraction and analysis from prokaryote and viral genomic sequences.
Applied Bioinformatics, 2(3),
pp. 165-168.
(PMID:15130803)
Kamal, Ahmed, Ramesh, G., Laxman, N., Ramulu, P., Srinivas, O., Neelima, K., Kondapi, Anand K., Sreenu, V.B. ORCID: https://orcid.org/0000-0001-6673-4697 and Nagarajaram, H.A.
(2002)
Design, synthesis, and evaluation of new noncross-linking pyrrolobenzodiazepine dimers with efficient DNA binding ability and potent antitumor activity.
Journal of Medicinal Chemistry, 45(21),
pp. 4679-4688.
(doi: 10.1021/jm020124h)
(PMID:12361394)
Varjak, Margus ORCID: https://orcid.org/0000-0003-2608-5148, Dietrich, Isabelle, Sreenu, Vattipally B.
ORCID: https://orcid.org/0000-0001-6673-4697, Till, Bethan Eluned, Merits, Andres, Kohl, Alain
ORCID: https://orcid.org/0000-0002-1523-9458 and Schnettler, Esther
Spindle-E acts antivirally against alphaviruses in mosquito cells.
Viruses, 10(2),
88.
(doi: 10.3390/v10020088)
(PMID:29463033)
(PMCID:PMC5850395)
Book Sections
Carmo, Alexandre M. and Sreenu, Vattipally B. ORCID: https://orcid.org/0000-0001-6673-4697
(2011)
A systematic and thorough search for domains of the scavenger receptor cysteine-rich Group-B family in the human genome.
In: Mahdavi, Mahmood A. (ed.)
Bioinformatics: Trends and Methodologies.
IntechOpen.
ISBN 9789533072821
(doi: 10.5772/19462)
Gundu, R.K., Swamynathan, S., Sreenu, V.B. ORCID: https://orcid.org/0000-0001-6673-4697, Pavan, N., Acharya, S. and Nagarajaram, H.A.
(2005)
Frontiers in bioinformatics research: the biodiversity issues.
In: Tandon, Pramod, Sharma, Manju and Swarup, Renu (eds.)
Biodiversity: Status and Prospects.
Narosa Publishing House: New Dehli.
ISBN 9788173196768
Supervision
Master's Projects
| Project title | Student | Year |
|---|---|---|
| Microsatellite analysis of African Swine Fever Virus (ASFV) | S.C. | 2017 |
| COVID-19 evolution – A bioinformatic analysis of the spike protein | D.A. | 2020 |
| SARS-CoV-2 Spike Protein Variant Analysis | R.D | 2021 |
| Mutational Analysis of the Nonstructural Protein 2 (NS3) Encoded Region in SASR-CoV-2 | M.K. | 2021 |
| Identification of compensatory mutations through bioinformatic analysis of SARS-CoV-2 variants from GISAID | P.T | 2022 |
|
The identification and analysis of SARS-CoV-2 M protein sequence variants for compensatory mutation by bioinformatic methods |
X.D. | 2022 |
|
Analysis of Microsatellite Variations in Monkeypox Virus – A Bioinformatic Approach |
H.Z. | 2023 |
|
Analysis of microsatellite variations in the SARS-CoV-2 genome |
W.K. | 2023 |
| An Mpox genome assembly pipeline for Nanopore tiled amplicon sequencing | S.M. | 2023 |
|
Identification of Compensatory Mutations in Monkeypox Variants through Bioinformatic Analysis |
Y.H. | 2023 |
Research datasets
2021
Scherer, C., Knowles, J., Vattipally, S. , Fredericks, A., Fuss, J., Maringer, K., Fernandez-Sesma, A., Merits, A., Varjak, M. , Kohl, A. and Schnettler, E. (2021) An Aedes aegypti-derived Ago2 knockout cell line to investigate arbovirus infections. [Data Collection]
2020
Gilbert, M., Sulikhan, N., Uphyrkina, O., Goncharuk, M., Kerley, L., Hernandez Castro, E., Reeve, R. , Seimon, T., McAloose, D., Seryodkin, I. V., Naidenko, S. V., Davis, C. A., Wilkie, G. S., Vattipally, S. , Adamson, W., Hinds, C., Thomson, E. , Willett, B. , Hosie, M. , Logan, N., McDonald, M. , Ossiboff, R. J., Shevtsova, E. I., Belyakin, S., Yurlova, A. A., Osofsky, S. A., Miquelle, D. G., Matthews, L. and Cleaveland, S. (2020) Distemper, extinction and vaccination of the Amur tiger. [Data Collection]
Alexander, A., Confort, M.-P., Desloire, S., Dunlop, J., Kuchi, S., Vattipally, S. , Mair, D., Wilkie, G., Da Silva Felipe, A., Brennan, B. , Ratinier, M., Arnaud, F. and Kohl, A. (2020) Development of a reverse genetics system for Toscana virus (lineage A). [Data Collection]
