Mr Ryan Ritchie

  • Laboratory Technician (Parasitology)

Publications

List by: Type | Date

Jump to: 2025 | 2023 | 2022 | 2021 | 2020 | 2018 | 2017 | 2016 | 2015 | 2013
Number of items: 15.

2025

Richards, S. et al. (2025) Longitudinal observational (single cohort) study on the causes of trypanocide failure in cases of african animal trypanosomosis in cattle near wildlife protected areas of Northern Tanzania. PLoS Neglected Tropical Diseases, 19(1), e0012541. (doi: 10.1371/journal.pntd.0012541) (PMID:39836697) (PMCID:PMC11785308)

2023

Rao, S. P. S. et al. (2023) Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science, 380(6652), pp. 1349-1356. (doi: 10.1126/science.adh0614) (PMID:37384702)

2022

Koester, D. C. et al. (2022) Discovery of novel quinoline-based proteasome inhibitors for human African trypanosomiasis (HAT). Journal of Medicinal Chemistry, 65(17), pp. 11776-11787. (doi: 10.1021/acs.jmedchem.2c00791) (PMID:35993839) (PMCID:PMC9469205)

Alpizar-Sosa, E. A. et al. (2022) Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response. PLoS Neglected Tropical Diseases, 16(9), e0010779. (doi: 10.1371/journal.pntd.0010779) (PMID:36170238) (PMCID:PMC9581426)

2021

Steketee, P. C. et al. (2021) Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition. PLoS Pathogens, 17(7), e1009734. (doi: 10.1371/journal.ppat.1009734) (PMID:34310651) (PMCID:PMC8384185)

McNae, I. W. et al. (2021) Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice. Nature Communications, 12, 1052. (doi: 10.1038/s41467-021-21273-6) (PMID:33594070) (PMCID:PMC7887271)

2020

Saldivia, M. et al. (2020) Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors. Nature Microbiology, 5(10), pp. 1207-1216. (doi: 10.1038/s41564-020-0745-6) (PMID:32661312) (PMCID:PMC7610364)

Rao, S. P.S. et al. (2020) Anti-Trypanosomal proteasome inhibitors cure hemolymphatic and meningoencephalic murine infection models of African Trypanosomiasis. Tropical Medicine and Infectious Disease, 5(1), 28. (doi: 10.3390/tropicalmed5010028) (PMID:32079320) (PMCID:PMC7157554)

Ritchie, Ryan, Barrett, Michael P. ORCID logoORCID: https://orcid.org/0000-0001-9447-3519, Mottram, Jeremy C. ORCID logoORCID: https://orcid.org/0000-0001-5574-3766 and Myburgh, Elmarie ORCID logoORCID: https://orcid.org/0000-0002-2007-5902 (2020) In vivo bioluminescence imaging to assess compound efficacy against Trypanosoma brucei. In: Michels, Paul A.M., Ginger, Michael L. and Zilberstein, Dan (eds.) Trypanosomatids: Methods and Protocols. Series: Methods in molecular biology (2116). Humana Press: New York, NY, pp. 801-817. ISBN 9781071602935 (doi: 10.1007/978-1-0716-0294-2_48)

2018

Ritchie, Neil D., Ritchie, Ryan, Bayes, Hannah K., Mitchell, Tim J. and Evans, Tom J. ORCID logoORCID: https://orcid.org/0000-0002-4140-6352 (2018) IL-17 can be protective or deleterious in murine pneumococcal pneumonia. PLoS Pathogens, 14(5), e1007099. (doi: 10.1371/journal.ppat.1007099) (PMID:29813133) (PMCID:PMC5993294)

Herbert, Jenny A., Mitchell, Andrea M., Ritchie, Ryan, Ma, Jiangtao, Ross-Hutchinson, Kirsty and Mitchell, Timothy J. (2018) Expression of the lux genes in Streptococcus pneumoniae modulates pilus expression and virulence. PLoS ONE, 13(1), e0189426. (doi: 10.1371/journal.pone.0189426) (PMID:29342160) (PMCID:PMC5771582)

2017

Fernandez-Cortes, Fernando, Serafim, Tiago D., Wilkes, Jonathan M. ORCID logoORCID: https://orcid.org/0000-0002-0920-6967, Jones, Nathaniel G., Ritchie, Ryan, McCulloch, Richard ORCID logoORCID: https://orcid.org/0000-0001-5739-976X and Mottram, Jeremy C. ORCID logoORCID: https://orcid.org/0000-0001-5574-3766 (2017) RNAi screening identifies Trypanosoma brucei stress response protein kinases required for survival in the mouse. Scientific Reports, 7, 6156. (doi: 10.1038/s41598-017-06501-8) (PMID:28733613) (PMCID:PMC5522463)

2016

Myburgh, Elmarie ORCID logoORCID: https://orcid.org/0000-0002-2007-5902, Ritchie, Ryan, Goundry, Amy Louise, O’Neill, Kerry, Marchesi, Francesco ORCID logoORCID: https://orcid.org/0000-0003-1179-5788 and Devaney, Eileen ORCID logoORCID: https://orcid.org/0000-0002-1935-834X (2016) Attempts to image the early inflammatory response during infection with the lymphatic filarial nematode Brugia pahangi in a mouse model. PLoS ONE, 11(12), e0168602. (doi: 10.1371/journal.pone.0168602) (PMID:27992545) (PMCID:PMC5161388)

2015

Coles, Jonathan A., Myburgh, Elmarie ORCID logoORCID: https://orcid.org/0000-0002-2007-5902, Ritchie, Ryan, Hamilton, Alana, Rodgers, Jean ORCID logoORCID: https://orcid.org/0000-0002-2093-3882, Mottram, Jeremy C. ORCID logoORCID: https://orcid.org/0000-0001-5574-3766, Barrett, Michael P. ORCID logoORCID: https://orcid.org/0000-0001-9447-3519 and Brewer, James M. ORCID logoORCID: https://orcid.org/0000-0001-7933-0915 (2015) Intravital imaging of a massive lymphocyte response in the cortical dura of mice after peripheral infection by trypanosomes. PLoS Neglected Tropical Diseases, 9(4), e0003714. (doi: 10.1371/journal.pntd.0003714) (PMID:25881126) (PMCID:PMC4400075)

2013

Myburgh, E. ORCID logoORCID: https://orcid.org/0000-0002-2007-5902, Coles, J.A., Ritchie, R., Kennedy, P.G.E., McLatchie, A., Rodgers, J. ORCID logoORCID: https://orcid.org/0000-0002-2093-3882, Taylor, M., Barrett, M. ORCID logoORCID: https://orcid.org/0000-0001-9447-3519, Brewer, J. ORCID logoORCID: https://orcid.org/0000-0001-7933-0915 and Mottram, J.C. ORCID logoORCID: https://orcid.org/0000-0001-5574-3766 (2013) In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis. PLoS Neglected Tropical Diseases, 7(8), e2384. (doi: 10.1371/journal.pntd.0002384)

This list was generated on Tue Jul 1 04:23:04 2025 BST.
Jump to: Articles | Book Sections
Number of items: 15.

Articles

Richards, S. et al. (2025) Longitudinal observational (single cohort) study on the causes of trypanocide failure in cases of african animal trypanosomosis in cattle near wildlife protected areas of Northern Tanzania. PLoS Neglected Tropical Diseases, 19(1), e0012541. (doi: 10.1371/journal.pntd.0012541) (PMID:39836697) (PMCID:PMC11785308)

Rao, S. P. S. et al. (2023) Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science, 380(6652), pp. 1349-1356. (doi: 10.1126/science.adh0614) (PMID:37384702)

Koester, D. C. et al. (2022) Discovery of novel quinoline-based proteasome inhibitors for human African trypanosomiasis (HAT). Journal of Medicinal Chemistry, 65(17), pp. 11776-11787. (doi: 10.1021/acs.jmedchem.2c00791) (PMID:35993839) (PMCID:PMC9469205)

Alpizar-Sosa, E. A. et al. (2022) Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response. PLoS Neglected Tropical Diseases, 16(9), e0010779. (doi: 10.1371/journal.pntd.0010779) (PMID:36170238) (PMCID:PMC9581426)

Steketee, P. C. et al. (2021) Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition. PLoS Pathogens, 17(7), e1009734. (doi: 10.1371/journal.ppat.1009734) (PMID:34310651) (PMCID:PMC8384185)

McNae, I. W. et al. (2021) Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice. Nature Communications, 12, 1052. (doi: 10.1038/s41467-021-21273-6) (PMID:33594070) (PMCID:PMC7887271)

Saldivia, M. et al. (2020) Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors. Nature Microbiology, 5(10), pp. 1207-1216. (doi: 10.1038/s41564-020-0745-6) (PMID:32661312) (PMCID:PMC7610364)

Rao, S. P.S. et al. (2020) Anti-Trypanosomal proteasome inhibitors cure hemolymphatic and meningoencephalic murine infection models of African Trypanosomiasis. Tropical Medicine and Infectious Disease, 5(1), 28. (doi: 10.3390/tropicalmed5010028) (PMID:32079320) (PMCID:PMC7157554)

Ritchie, Neil D., Ritchie, Ryan, Bayes, Hannah K., Mitchell, Tim J. and Evans, Tom J. ORCID logoORCID: https://orcid.org/0000-0002-4140-6352 (2018) IL-17 can be protective or deleterious in murine pneumococcal pneumonia. PLoS Pathogens, 14(5), e1007099. (doi: 10.1371/journal.ppat.1007099) (PMID:29813133) (PMCID:PMC5993294)

Herbert, Jenny A., Mitchell, Andrea M., Ritchie, Ryan, Ma, Jiangtao, Ross-Hutchinson, Kirsty and Mitchell, Timothy J. (2018) Expression of the lux genes in Streptococcus pneumoniae modulates pilus expression and virulence. PLoS ONE, 13(1), e0189426. (doi: 10.1371/journal.pone.0189426) (PMID:29342160) (PMCID:PMC5771582)

Fernandez-Cortes, Fernando, Serafim, Tiago D., Wilkes, Jonathan M. ORCID logoORCID: https://orcid.org/0000-0002-0920-6967, Jones, Nathaniel G., Ritchie, Ryan, McCulloch, Richard ORCID logoORCID: https://orcid.org/0000-0001-5739-976X and Mottram, Jeremy C. ORCID logoORCID: https://orcid.org/0000-0001-5574-3766 (2017) RNAi screening identifies Trypanosoma brucei stress response protein kinases required for survival in the mouse. Scientific Reports, 7, 6156. (doi: 10.1038/s41598-017-06501-8) (PMID:28733613) (PMCID:PMC5522463)

Myburgh, Elmarie ORCID logoORCID: https://orcid.org/0000-0002-2007-5902, Ritchie, Ryan, Goundry, Amy Louise, O’Neill, Kerry, Marchesi, Francesco ORCID logoORCID: https://orcid.org/0000-0003-1179-5788 and Devaney, Eileen ORCID logoORCID: https://orcid.org/0000-0002-1935-834X (2016) Attempts to image the early inflammatory response during infection with the lymphatic filarial nematode Brugia pahangi in a mouse model. PLoS ONE, 11(12), e0168602. (doi: 10.1371/journal.pone.0168602) (PMID:27992545) (PMCID:PMC5161388)

Coles, Jonathan A., Myburgh, Elmarie ORCID logoORCID: https://orcid.org/0000-0002-2007-5902, Ritchie, Ryan, Hamilton, Alana, Rodgers, Jean ORCID logoORCID: https://orcid.org/0000-0002-2093-3882, Mottram, Jeremy C. ORCID logoORCID: https://orcid.org/0000-0001-5574-3766, Barrett, Michael P. ORCID logoORCID: https://orcid.org/0000-0001-9447-3519 and Brewer, James M. ORCID logoORCID: https://orcid.org/0000-0001-7933-0915 (2015) Intravital imaging of a massive lymphocyte response in the cortical dura of mice after peripheral infection by trypanosomes. PLoS Neglected Tropical Diseases, 9(4), e0003714. (doi: 10.1371/journal.pntd.0003714) (PMID:25881126) (PMCID:PMC4400075)

Myburgh, E. ORCID logoORCID: https://orcid.org/0000-0002-2007-5902, Coles, J.A., Ritchie, R., Kennedy, P.G.E., McLatchie, A., Rodgers, J. ORCID logoORCID: https://orcid.org/0000-0002-2093-3882, Taylor, M., Barrett, M. ORCID logoORCID: https://orcid.org/0000-0001-9447-3519, Brewer, J. ORCID logoORCID: https://orcid.org/0000-0001-7933-0915 and Mottram, J.C. ORCID logoORCID: https://orcid.org/0000-0001-5574-3766 (2013) In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis. PLoS Neglected Tropical Diseases, 7(8), e2384. (doi: 10.1371/journal.pntd.0002384)

Book Sections

Ritchie, Ryan, Barrett, Michael P. ORCID logoORCID: https://orcid.org/0000-0001-9447-3519, Mottram, Jeremy C. ORCID logoORCID: https://orcid.org/0000-0001-5574-3766 and Myburgh, Elmarie ORCID logoORCID: https://orcid.org/0000-0002-2007-5902 (2020) In vivo bioluminescence imaging to assess compound efficacy against Trypanosoma brucei. In: Michels, Paul A.M., Ginger, Michael L. and Zilberstein, Dan (eds.) Trypanosomatids: Methods and Protocols. Series: Methods in molecular biology (2116). Humana Press: New York, NY, pp. 801-817. ISBN 9781071602935 (doi: 10.1007/978-1-0716-0294-2_48)

This list was generated on Wed Jul 2 06:24:33 2025 BST.