Dr Quan Gu
- Bioinformatician (Virology)
telephone:
01413304019
email:
Quan.Gu@glasgow.ac.uk
RI of Infection, Immun & Inflam, Centre for Virus Research
https://orcid.org/0000-0002-1201-6734Biography
Quan Gu is currently a Research Bioinformatician at MRC-University of Glasgow Centre for Virus Research. Prior to his position at Glasgow, he was a postdoctoral research associate in Bioinformatics at Imperial College London.
Research interests
Viral genomics & bioinformatics programme
Quan Gu's broad research interests include:
Transcriptomics analysis including RNA-Seq and scRNA-Seq;
Machine learning and pattern recognition;
Nuclear magnetic resonance and mass spectrum data modeling and analysis.
Publications
2023
Cao, G. et al. (2023) Single-cell dissection of cervical cancer reveals key subsets of the tumor immune microenvironment. EMBO Journal, 42(16), e110757. (doi: 10.15252/embj.2022110757) (PMID:37427448)
Pinto, R. M. et al. (2023) BTN3A3 evasion promotes the zoonotic potential of influenza A viruses. Nature, 619(7969), pp. 338-347. (doi: 10.1038/s41586-023-06261-8) (PMID:37380775)
Hardy, A. et al. (2023) The timing and magnitude of the type I interferon response are correlated with disease tolerance in arbovirus infection. mBio, 14(3), e0010123. (doi: 10.1128/mbio.00101-23) (PMID:37097030) (PMCID:PMC10294695)
2022
Chai, H., Gu, Q. , Robertson, D. L. and Hughes, J. (2022) Defining the characteristics of interferon-alpha–stimulated human genes: insight from expression data and machine learning. GigaScience, 11, giac103. (doi: 10.1093/gigascience/giac103) (PMID:36399061) (PMCID:PMC9673497)
Chai, H., Gu, Q. , Hughes, J. and Robertson, D. L. (2022) In silico prediction of HIV-1-host molecular interactions and their directionality. PLoS Computational Biology, 18(2), e1009720. (doi: 10.1371/journal.pcbi.1009720) (PMID:35134057) (PMCID:PMC8856524)
2021
Amat, J. A.R. et al. (2021) Long-term adaptation following influenza A virus host shifts results in increased within-host viral fitness due to higher replication rates, broader dissemination within the respiratory epithelium and reduced tissue damage. PLoS Pathogens, 17(12), e1010174. (doi: 10.1371/journal.ppat.1010174) (PMID:34919598) (PMCID:PMC8735595)
Herder, V. et al. (2021) Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defences. PLoS Biology, 19(12), e3001065. (doi: 10.1371/journal.pbio.3001065) (PMID:34932557) (PMCID:PMC8765667)
Wickenhagen, A. et al. (2021) A prenylated dsRNA sensor protects against severe COVID-19. Science, 374(6567), eabj3624. (doi: 10.1126/science.abj3624) (PMID:34581622)
Lau, B. et al. (2021) Human cytomegalovirus RNA2.7 is required for upregulating multiple cellular genes to promote cell motility and viral spread late in lytic infection. Journal of Virology, 95(20), e00698-21. (doi: 10.1128/JVI.00698-21) (PMID:34346763) (PMCID:PMC8475523)
Shaw, A. E. et al. (2021) The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. PLoS Biology, 19(9), e3001352. (doi: 10.1371/journal.pbio.3001352) (PMID:34491982) (PMCID:PMC8423302)
Baksmeier, C. et al. (2021) Modified recombinant human IgG1-Fc is superior to natural intravenous immunoglobulin at inhibiting immune-mediated demyelination. Immunology, 164(1), pp. 90-105. (doi: 10.1111/imm.13341) (PMID:33880776) (PMCID:PMC8358725)
Gallo, G. et al. (2021) Interactions of viral proteins from pathogenic and low or non-pathogenic orthohantaviruses with human type I interferon signaling. Viruses, 13(1), 140. (doi: 10.3390/v13010140) (PMID:33478127) (PMCID:PMC7835746)
Schultz, V. et al. (2021) Zika virus infection leads to demyelination and axonal injury in mature CNS cultures. Viruses, 13(1), 91. (doi: 10.3390/v13010091) (PMID:33440758) (PMCID:PMC7827345)
2020
Dimitrov, D. and Gu, Q. (2020) BingleSeq: A user-friendly R package for bulk and single-cell RNA-Seq data analysis. PeerJ, 8, e10469. (doi: 10.7717/peerj.10469) (PMID:33391870) (PMCID:PMC7761193)
Lau, B. , Kerr, K., Gu, Q. , Nightingale, K., Antrobus, R., Suarez, N. M., Stanton, R. J., Wang, E. C., Weekes, M. P. and Davison, A. J. (2020) Human cytomegalovirus long non-coding RNA1.2 suppresses extracellular release of the pro-inflammatory cytokine IL-6 by blocking NF-κB activation. Frontiers in Cellular and Infection Microbiology, 10, 361. (doi: 10.3389/fcimb.2020.00361) (PMID:32793512)
Sook Yuin Ho, J. et al. (2020) Hybrid gene origination creates human-virus chimeric proteins during infection. Cell, 181(7), 1502-1517.e23. (doi: 10.1016/j.cell.2020.05.035) (PMID:32559462) (PMCID:PMC7323901)
2019
McFarlane, S. et al. (2019) The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection. PLoS Pathogens, 15(3), e1007667. (doi: 10.1371/journal.ppat.1007667) (PMID:30901352) (PMCID:PMC6472835)
2018
Gu, Q. and Veselkov, K. (2018) Bi-clustering of metabolic data using matrix factorization tools. Methods, 151, pp. 12-20. (doi: 10.1016/j.ymeth.2018.02.004) (PMID:29438828) (PMCID:PMC6297113)
Selinger, M., Wilkie, G. S., Tong, L., Gu, Q. , Schnettler, E., Grubhoffer, L. and Kohl, A. (2018) Corrigendum: Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection. Journal of General Virology, 99(8), pp. 1147-1149. (doi: 10.1099/jgv.0.001109) (PMID:30067173)
Chauché, C., Nogales, A., Zhu, H., Goldfarb, D., Shanizza A.I., A., Gu, Q. , Parrish, C.R., Martínez-Sobrido, L., Marshall, J.F. and Murcia, P.R. (2018) Mammalian adaptation of an avian influenza A virus involves stepwise changes in NS1. Journal of Virology, 92(5), e01875-17. (doi: 10.1128/JVI.01875-17) (PMID:29237841) (PMCID:PMC5809720)
2017
Shaw, A. E. et al. (2017) Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses. PLoS Biology, 15(12), e2004086. (doi: 10.1371/journal.pbio.2004086) (PMID:29253856) (PMCID:PMC574750)
Bhome, R. et al. (2017) Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression. Aging, 9(12), pp. 2666-2694. (doi: 10.18632/aging.101355) (PMID:29283887)
Klymenko, T. et al. (2017) RNA-Seq analysis of differentiated keratinocytes reveals a massive response to late events during human papillomavirus 16 infection, including loss of epithelial barrier function. Journal of Virology, 91(24), e01001-17. (doi: 10.1128/JVI.01001-17) (PMID:29021401) (PMCID:PMC5709591)
Selinger, M., Wilkie, G. S., Tong, L., Gu, Q. , Schnettler, E., Grubhoffer, L. and Kohl, A. (2017) Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection. Journal of General Virology, 98(8), pp. 2043-2060. (doi: 10.1099/jgv.0.000853) (PMID:28786780)
Dumas, M.-E. et al. (2017) Microbial-host co-metabolites are prodromal markers predicting phenotypic heterogeneity in behavior, obesity, and impaired glucose tolerance. Cell Reports, 20(1), pp. 136-148. (doi: 10.1016/j.celrep.2017.06.039) (PMID:28683308)
2016
Dumas, M.-E. et al. (2016) Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series. Genome Medicine, 8, 101. (doi: 10.1186/s13073-016-0352-6) (PMID:27716393) (PMCID:PMC5045612)
Ratinier, M., Shaw, A. E., Barry, G., Gu, Q. , Di Gialleonardo, L., Janowicz, A., Varela, M., Randall, R. E., Caporale, M. and Palmarini, M. (2016) Bluetongue virus NS4 protein is an interferon antagonist and a determinant of virus virulence. Journal of Virology, 90(11), pp. 5427-5439. (doi: 10.1128/JVI.00422-16) (PMID:27009961) (PMCID:PMC4934764)
Orton, R.J. , Gu, Q. , Hughes, J. , Maabar, M., Modha, S. , Vattipally, S. , Wilkie, G.S. and Davison, A. (2016) Bioinformatics tools for analysing viral genomic data. Revue scientifique et technique (International Office of Epizootics), 35(1), pp. 241-285. (doi: 10.20506/rst.35.1.2432) (PMID:27217183)
2015
Gu, Q. , Ding, Y.-S. and Zhang, T.-L. (2015) An ensemble classifier based prediction of G-protein-coupled receptor classes in low homology. Neurocomputing, 154, pp. 110-118. (doi: 10.1016/j.neucom.2014.12.013)
Blomström, A.-L. et al. (2015) Transcriptome analysis reveals the host response to Schmallenberg virus in bovine cells and antagonistic effects of the NSs protein. BMC Genomics, 16, 324. (doi: 10.1186/s12864-015-1538-9) (PMID:25896169) (PMCID:PMC4404599)
2014
Hudson, N. J., Baker, M. L., Hart, N. S., Wynne, J. W., Gu, Q. , Huang, Z., Zhang, G., Ingham, A. B., Wang, L. and Reverter, A. (2014) Sensory rewiring in an echolocator: genome-wide modification of retinogenic and auditory genes in the bat myotis davidii. G3: Genes, Genomes, Genetics, 4(10), pp. 1825-1835. (doi: 10.1534/g3.114.011262) (PMID:25096539) (PMCID:PMC4199690)
2011
Hudson, N. J., Gu, Q. , Nagaraj, S. H., Ding, Y.-S., Dalrymple, B. P. and Reverter, A. (2011) Eukaryotic evolutionary transitions are associated with extreme codon bias in functionally-related proteins. PLoS ONE, 6(9), e25457. (doi: 10.1371/journal.pone.0025457) (PMID:21966531) (PMCID:PMC3179510)
Gu, Q. , Nagaraj, S. H., Hudson, N. J., Dalrymple, B. P. and Reverter, A. (2011) Genome-wide patterns of promoter sharing and co-expression in bovine skeletal muscle. BMC Genomics, 12, 23. (doi: 10.1186/1471-2164-12-23) (PMID:21226902) (PMCID:PMC3025955)
2010
Gu, Q. , Ding, Y.-S. and Zhang, T.-L. (2010) Prediction of G-protein-coupled receptor classes in low homology using Chou's pseudo amino acid composition with approximate entropy and hydrophobicity patterns. Protein and Peptide Letters, 17(5), pp. 559-567. (doi: 10.2174/092986610791112693)
Shen, Y.-Z., Ding, Y.-S., Gu, Q. and Chou, K.-C. (2010) Identifying the hub proteins from complicated membrane protein network systems. Medicinal Chemistry, 6(3), pp. 165-173. (doi: 10.2174/1573406411006030165) (PMID:20507268)
Gu, Q. , Ding, Y.-S., Jiang, X.-Y. and Zhang, T.-L. (2010) Prediction of subcellular location apoptosis proteins with ensemble classifier and feature selection. Amino Acids, 38(4), pp. 975-983. (doi: 10.1007/s00726-008-0209-4) (PMID:19048186)
2009
Ding, Y.-S., Zhang, T.-L., Gu, Q. , Zhao, P.-Y. and Chou, K.-C. (2009) Using maximum entropy model to predict protein secondary structure with single sequence. Protein and Peptide Letters, 16(5), pp. 552-560. (doi: 10.2174/092986609788167833) (PMID:19442235)
2008
Jiang, X., Wei, R., Zhang, T. and Gu, Q. (2008) Using the concept of chous pseudo amino acid composition to predict apoptosis proteins subcellular location: an approach by approximate entropy. Protein and Peptide Letters, 15(4), pp. 392-396.
Articles
Cao, G. et al. (2023) Single-cell dissection of cervical cancer reveals key subsets of the tumor immune microenvironment. EMBO Journal, 42(16), e110757. (doi: 10.15252/embj.2022110757) (PMID:37427448)
Pinto, R. M. et al. (2023) BTN3A3 evasion promotes the zoonotic potential of influenza A viruses. Nature, 619(7969), pp. 338-347. (doi: 10.1038/s41586-023-06261-8) (PMID:37380775)
Hardy, A. et al. (2023) The timing and magnitude of the type I interferon response are correlated with disease tolerance in arbovirus infection. mBio, 14(3), e0010123. (doi: 10.1128/mbio.00101-23) (PMID:37097030) (PMCID:PMC10294695)
Chai, H., Gu, Q. , Robertson, D. L. and Hughes, J. (2022) Defining the characteristics of interferon-alpha–stimulated human genes: insight from expression data and machine learning. GigaScience, 11, giac103. (doi: 10.1093/gigascience/giac103) (PMID:36399061) (PMCID:PMC9673497)
Chai, H., Gu, Q. , Hughes, J. and Robertson, D. L. (2022) In silico prediction of HIV-1-host molecular interactions and their directionality. PLoS Computational Biology, 18(2), e1009720. (doi: 10.1371/journal.pcbi.1009720) (PMID:35134057) (PMCID:PMC8856524)
Amat, J. A.R. et al. (2021) Long-term adaptation following influenza A virus host shifts results in increased within-host viral fitness due to higher replication rates, broader dissemination within the respiratory epithelium and reduced tissue damage. PLoS Pathogens, 17(12), e1010174. (doi: 10.1371/journal.ppat.1010174) (PMID:34919598) (PMCID:PMC8735595)
Herder, V. et al. (2021) Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defences. PLoS Biology, 19(12), e3001065. (doi: 10.1371/journal.pbio.3001065) (PMID:34932557) (PMCID:PMC8765667)
Wickenhagen, A. et al. (2021) A prenylated dsRNA sensor protects against severe COVID-19. Science, 374(6567), eabj3624. (doi: 10.1126/science.abj3624) (PMID:34581622)
Lau, B. et al. (2021) Human cytomegalovirus RNA2.7 is required for upregulating multiple cellular genes to promote cell motility and viral spread late in lytic infection. Journal of Virology, 95(20), e00698-21. (doi: 10.1128/JVI.00698-21) (PMID:34346763) (PMCID:PMC8475523)
Shaw, A. E. et al. (2021) The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. PLoS Biology, 19(9), e3001352. (doi: 10.1371/journal.pbio.3001352) (PMID:34491982) (PMCID:PMC8423302)
Baksmeier, C. et al. (2021) Modified recombinant human IgG1-Fc is superior to natural intravenous immunoglobulin at inhibiting immune-mediated demyelination. Immunology, 164(1), pp. 90-105. (doi: 10.1111/imm.13341) (PMID:33880776) (PMCID:PMC8358725)
Gallo, G. et al. (2021) Interactions of viral proteins from pathogenic and low or non-pathogenic orthohantaviruses with human type I interferon signaling. Viruses, 13(1), 140. (doi: 10.3390/v13010140) (PMID:33478127) (PMCID:PMC7835746)
Schultz, V. et al. (2021) Zika virus infection leads to demyelination and axonal injury in mature CNS cultures. Viruses, 13(1), 91. (doi: 10.3390/v13010091) (PMID:33440758) (PMCID:PMC7827345)
Dimitrov, D. and Gu, Q. (2020) BingleSeq: A user-friendly R package for bulk and single-cell RNA-Seq data analysis. PeerJ, 8, e10469. (doi: 10.7717/peerj.10469) (PMID:33391870) (PMCID:PMC7761193)
Lau, B. , Kerr, K., Gu, Q. , Nightingale, K., Antrobus, R., Suarez, N. M., Stanton, R. J., Wang, E. C., Weekes, M. P. and Davison, A. J. (2020) Human cytomegalovirus long non-coding RNA1.2 suppresses extracellular release of the pro-inflammatory cytokine IL-6 by blocking NF-κB activation. Frontiers in Cellular and Infection Microbiology, 10, 361. (doi: 10.3389/fcimb.2020.00361) (PMID:32793512)
Sook Yuin Ho, J. et al. (2020) Hybrid gene origination creates human-virus chimeric proteins during infection. Cell, 181(7), 1502-1517.e23. (doi: 10.1016/j.cell.2020.05.035) (PMID:32559462) (PMCID:PMC7323901)
McFarlane, S. et al. (2019) The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection. PLoS Pathogens, 15(3), e1007667. (doi: 10.1371/journal.ppat.1007667) (PMID:30901352) (PMCID:PMC6472835)
Gu, Q. and Veselkov, K. (2018) Bi-clustering of metabolic data using matrix factorization tools. Methods, 151, pp. 12-20. (doi: 10.1016/j.ymeth.2018.02.004) (PMID:29438828) (PMCID:PMC6297113)
Selinger, M., Wilkie, G. S., Tong, L., Gu, Q. , Schnettler, E., Grubhoffer, L. and Kohl, A. (2018) Corrigendum: Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection. Journal of General Virology, 99(8), pp. 1147-1149. (doi: 10.1099/jgv.0.001109) (PMID:30067173)
Chauché, C., Nogales, A., Zhu, H., Goldfarb, D., Shanizza A.I., A., Gu, Q. , Parrish, C.R., Martínez-Sobrido, L., Marshall, J.F. and Murcia, P.R. (2018) Mammalian adaptation of an avian influenza A virus involves stepwise changes in NS1. Journal of Virology, 92(5), e01875-17. (doi: 10.1128/JVI.01875-17) (PMID:29237841) (PMCID:PMC5809720)
Shaw, A. E. et al. (2017) Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses. PLoS Biology, 15(12), e2004086. (doi: 10.1371/journal.pbio.2004086) (PMID:29253856) (PMCID:PMC574750)
Bhome, R. et al. (2017) Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression. Aging, 9(12), pp. 2666-2694. (doi: 10.18632/aging.101355) (PMID:29283887)
Klymenko, T. et al. (2017) RNA-Seq analysis of differentiated keratinocytes reveals a massive response to late events during human papillomavirus 16 infection, including loss of epithelial barrier function. Journal of Virology, 91(24), e01001-17. (doi: 10.1128/JVI.01001-17) (PMID:29021401) (PMCID:PMC5709591)
Selinger, M., Wilkie, G. S., Tong, L., Gu, Q. , Schnettler, E., Grubhoffer, L. and Kohl, A. (2017) Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection. Journal of General Virology, 98(8), pp. 2043-2060. (doi: 10.1099/jgv.0.000853) (PMID:28786780)
Dumas, M.-E. et al. (2017) Microbial-host co-metabolites are prodromal markers predicting phenotypic heterogeneity in behavior, obesity, and impaired glucose tolerance. Cell Reports, 20(1), pp. 136-148. (doi: 10.1016/j.celrep.2017.06.039) (PMID:28683308)
Dumas, M.-E. et al. (2016) Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series. Genome Medicine, 8, 101. (doi: 10.1186/s13073-016-0352-6) (PMID:27716393) (PMCID:PMC5045612)
Ratinier, M., Shaw, A. E., Barry, G., Gu, Q. , Di Gialleonardo, L., Janowicz, A., Varela, M., Randall, R. E., Caporale, M. and Palmarini, M. (2016) Bluetongue virus NS4 protein is an interferon antagonist and a determinant of virus virulence. Journal of Virology, 90(11), pp. 5427-5439. (doi: 10.1128/JVI.00422-16) (PMID:27009961) (PMCID:PMC4934764)
Orton, R.J. , Gu, Q. , Hughes, J. , Maabar, M., Modha, S. , Vattipally, S. , Wilkie, G.S. and Davison, A. (2016) Bioinformatics tools for analysing viral genomic data. Revue scientifique et technique (International Office of Epizootics), 35(1), pp. 241-285. (doi: 10.20506/rst.35.1.2432) (PMID:27217183)
Gu, Q. , Ding, Y.-S. and Zhang, T.-L. (2015) An ensemble classifier based prediction of G-protein-coupled receptor classes in low homology. Neurocomputing, 154, pp. 110-118. (doi: 10.1016/j.neucom.2014.12.013)
Blomström, A.-L. et al. (2015) Transcriptome analysis reveals the host response to Schmallenberg virus in bovine cells and antagonistic effects of the NSs protein. BMC Genomics, 16, 324. (doi: 10.1186/s12864-015-1538-9) (PMID:25896169) (PMCID:PMC4404599)
Hudson, N. J., Baker, M. L., Hart, N. S., Wynne, J. W., Gu, Q. , Huang, Z., Zhang, G., Ingham, A. B., Wang, L. and Reverter, A. (2014) Sensory rewiring in an echolocator: genome-wide modification of retinogenic and auditory genes in the bat myotis davidii. G3: Genes, Genomes, Genetics, 4(10), pp. 1825-1835. (doi: 10.1534/g3.114.011262) (PMID:25096539) (PMCID:PMC4199690)
Hudson, N. J., Gu, Q. , Nagaraj, S. H., Ding, Y.-S., Dalrymple, B. P. and Reverter, A. (2011) Eukaryotic evolutionary transitions are associated with extreme codon bias in functionally-related proteins. PLoS ONE, 6(9), e25457. (doi: 10.1371/journal.pone.0025457) (PMID:21966531) (PMCID:PMC3179510)
Gu, Q. , Nagaraj, S. H., Hudson, N. J., Dalrymple, B. P. and Reverter, A. (2011) Genome-wide patterns of promoter sharing and co-expression in bovine skeletal muscle. BMC Genomics, 12, 23. (doi: 10.1186/1471-2164-12-23) (PMID:21226902) (PMCID:PMC3025955)
Gu, Q. , Ding, Y.-S. and Zhang, T.-L. (2010) Prediction of G-protein-coupled receptor classes in low homology using Chou's pseudo amino acid composition with approximate entropy and hydrophobicity patterns. Protein and Peptide Letters, 17(5), pp. 559-567. (doi: 10.2174/092986610791112693)
Shen, Y.-Z., Ding, Y.-S., Gu, Q. and Chou, K.-C. (2010) Identifying the hub proteins from complicated membrane protein network systems. Medicinal Chemistry, 6(3), pp. 165-173. (doi: 10.2174/1573406411006030165) (PMID:20507268)
Gu, Q. , Ding, Y.-S., Jiang, X.-Y. and Zhang, T.-L. (2010) Prediction of subcellular location apoptosis proteins with ensemble classifier and feature selection. Amino Acids, 38(4), pp. 975-983. (doi: 10.1007/s00726-008-0209-4) (PMID:19048186)
Ding, Y.-S., Zhang, T.-L., Gu, Q. , Zhao, P.-Y. and Chou, K.-C. (2009) Using maximum entropy model to predict protein secondary structure with single sequence. Protein and Peptide Letters, 16(5), pp. 552-560. (doi: 10.2174/092986609788167833) (PMID:19442235)
Jiang, X., Wei, R., Zhang, T. and Gu, Q. (2008) Using the concept of chous pseudo amino acid composition to predict apoptosis proteins subcellular location: an approach by approximate entropy. Protein and Peptide Letters, 15(4), pp. 392-396.
Research datasets
2023
Meehan, G. , Herder, V. , Allan, J., Huang, X., Kerr, K., Correa Mendonca, D. , Ilia, G., Wright, D. , Nomikou, K., Gu, Q. , Molina Arias, S., Hansmann, F., Hardas, A., Attipa, C., De Lorenzo, G. , Cowton, V., Upfold, N. , Palmalux, N., Brown, J., Barclay, W., Da Silva Filipe, A. , Furnon, W. , Patel, A. and Palmarini, M. (2023) Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning. [Data Collection]
2021
Wickenhagen, A., Sugrue, E. , Lytras, S., Kuchi, S., Noerenberg, M. , Turnbull, M. , Loney, C. , Herder, V., Allan, J., Jarmson, I., Cameron Ruiz, N., Varjak, M. , Pinto, R. , Lee, J. Y., Iselin, L., Palmalux, N., Stewart, D., Swingler, S., Greenwood, E. J. D., Crozier, T. W. M., Gu, Q. , Davies, E., Clohisey, S., Wang, B., Trindade Maranhã Costa, F., Santana, M. F., Carlos de Lima Ferreira, L., Murphy, L., Fawkes, A., Meynert, A., Grimes, G., ISARICC investigators, , Da Silva Filho, J. , Marti, M. , Hughes, J. , Stanton, R. J., Wang, E. C. Y., Ho, A. , Davis, I., Jarrett, R. , Castello, A. , Robertson, D. , Semple, M. G., Openshaw, P. J. M., Palmarini, M. , Lehner, P. J., Baillie, K., Rihn, S. and Wilson, S. (2021) A Prenylated dsRNA Sensor Protects Against Severe COVID-19. [Data Collection]
Shaw, A., Rihn, S. , Mollentze, N. , Wickenhagen, A., Stewart, D., Orton, R. , Kuchi, S., Bakshi, S., Collados Rodriguez, M. , Turnbull, M. , Busby, J., Gu, Q. , Smollett, K., Bamford, C., Sugrue, E. , Johnson, P. , Da Silva Filipe, A. , Castello, A. , Streicker, D. , Robertson, D. , Palmarini, M. and Wilson, S. (2021) The 'antiviral state' has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. [Data Collection] (Unpublished)
