Dr Quan Gu

  • Research Scientist (Virology)

email: Quan.Gu@glasgow.ac.uk

RI of Infection, Immun & Inflam, Centre for Virus Research

Import to contacts

ORCID iDhttps://orcid.org/0000-0002-1201-6734

Biography

Quan Gu is a Research Bioinformatician at the MRC-University of Glasgow Centre for Virus Research. Before his position at Glasgow, he was a postdoctoral research associate in Bioinformatics at Imperial College London.

Research interests

Quan Gu's broad research interests include:
Transcriptomics analysis, Metabolomics analysis and multi-omics analysis;
Machine learning and artificial intelligence.

Publications

List by: Type | Date

Jump to: 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2011 | 2010 | 2009 | 2008
Number of items: 45.

2025

Petit, M. et al. (2025) Multi-omics analysis of SFTS virus infection in Rhipicephalus microplus cells reveals antiviral tick factors. Nature Communications, 16(1), 4732. (doi: 10.1038/s41467-025-59565-w) (PMID:40399277) (PMCID:PMC12095547)

Chen, Honglin, Charles, Philip D., Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Liberatori, Sabrina, Robertson, David L. ORCID logoORCID: https://orcid.org/0000-0001-6338-0221, Palmarini, Massimo ORCID logoORCID: https://orcid.org/0000-0001-7007-4070, Wilson, Sam J. ORCID logoORCID: https://orcid.org/0000-0002-6065-0895, Mohammed, Shabaz and Castello, Alfredo ORCID logoORCID: https://orcid.org/0000-0002-1499-4662 (2025) Omics analyses uncover host networks defining virus-permissive and -hostile cellular states. Molecular and Cellular Proteomics, 24(5), 100966. (doi: 10.1016/j.mcpro.2025.100966) (PMID:40204275) (PMCID:PMC12136899)

Faizo, Arwa Ali A, Bellward, Clare, Hernandez-Lopez, Hegel R., Stevenson, Andrew, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734 and Graham, Sheila ORCID logoORCID: https://orcid.org/0000-0002-7140-8279 (2025) The splicing factor kinase, SR protein kinase 1 (SRPK1) is essential for late events in the human papillomavirus life cycle. PLoS Pathogens, 21(4), e1012697. (doi: 10.1371/journal.ppat.1012697) (PMID:40203066) (PMCID:PMC12013937)

2024

Ruscica, V. et al. (2024) XRN1 supplies free nucleotides to feed alphavirus replication. bioRxiv, (doi: 10.1101/2024.12.09.625895)

Herder, V. et al. (2024) Correlates of disease severity in bluetongue as a model of acute arbovirus infection. PLoS Pathogens, 20(8), e1012466. (doi: 10.1371/journal.ppat.1012466) (PMID:39150989) (PMCID:PMC11357116)

Herder, V. et al. (2024) A machine learning framework to identify the correlates of disease severity in acute arbovirus infection. bioRxiv, (doi: 10.1101/2024.02.23.581333) (PMID:PPR810635)

2023

Meehan, G. R. et al. (2023) Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning. PLoS Pathogens, 19(11), e1011589. (doi: 10.1371/journal.ppat.1011589) (PMID:37934791) (PMCID:PMC10656012)

Cao, G. et al. (2023) Single-cell dissection of cervical cancer reveals key subsets of the tumor immune microenvironment. EMBO Journal, 42(16), e110757. (doi: 10.15252/embj.2022110757) (PMID:37427448)

Pinto, R. M. et al. (2023) BTN3A3 evasion promotes the zoonotic potential of influenza A viruses. Nature, 619(7969), pp. 338-347. (doi: 10.1038/s41586-023-06261-8) (PMID:37380775)

Hardy, A. et al. (2023) The timing and magnitude of the type I interferon response are correlated with disease tolerance in arbovirus infection. mBio, 14(3), e0010123. (doi: 10.1128/mbio.00101-23) (PMID:37097030) (PMCID:PMC10294695)

2022

Chai, Haiting, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Robertson, David L. ORCID logoORCID: https://orcid.org/0000-0001-6338-0221 and Hughes, Joseph ORCID logoORCID: https://orcid.org/0000-0003-2556-2563 (2022) Defining the characteristics of interferon-alpha–stimulated human genes: insight from expression data and machine learning. GigaScience, 11, giac103. (doi: 10.1093/gigascience/giac103) (PMID:36399061) (PMCID:PMC9673497)

Chai, Haiting, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Hughes, Joseph ORCID logoORCID: https://orcid.org/0000-0003-2556-2563 and Robertson, David L. ORCID logoORCID: https://orcid.org/0000-0001-6338-0221 (2022) In silico prediction of HIV-1-host molecular interactions and their directionality. PLoS Computational Biology, 18(2), e1009720. (doi: 10.1371/journal.pcbi.1009720) (PMID:35134057) (PMCID:PMC8856524)

2021

Amat, J. A.R. et al. (2021) Long-term adaptation following influenza A virus host shifts results in increased within-host viral fitness due to higher replication rates, broader dissemination within the respiratory epithelium and reduced tissue damage. PLoS Pathogens, 17(12), e1010174. (doi: 10.1371/journal.ppat.1010174) (PMID:34919598) (PMCID:PMC8735595)

Herder, V. et al. (2021) Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defences. PLoS Biology, 19(12), e3001065. (doi: 10.1371/journal.pbio.3001065) (PMID:34932557) (PMCID:PMC8765667)

Wickenhagen, A. et al. (2021) A prenylated dsRNA sensor protects against severe COVID-19. Science, 374(6567), eabj3624. (doi: 10.1126/science.abj3624) (PMID:34581622) (PMCID:PMC7612834)

Lau, B. et al. (2021) Human cytomegalovirus RNA2.7 is required for upregulating multiple cellular genes to promote cell motility and viral spread late in lytic infection. Journal of Virology, 95(20), e00698-21. (doi: 10.1128/JVI.00698-21) (PMID:34346763) (PMCID:PMC8475523)

Shaw, A. E. et al. (2021) The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. PLoS Biology, 19(9), e3001352. (doi: 10.1371/journal.pbio.3001352) (PMID:34491982) (PMCID:PMC8423302)

Baksmeier, C. et al. (2021) Modified recombinant human IgG1-Fc is superior to natural intravenous immunoglobulin at inhibiting immune-mediated demyelination. Immunology, 164(1), pp. 90-105. (doi: 10.1111/imm.13341) (PMID:33880776) (PMCID:PMC8358725)

Gallo, G. et al. (2021) Interactions of viral proteins from pathogenic and low or non-pathogenic orthohantaviruses with human type I interferon signaling. Viruses, 13(1), 140. (doi: 10.3390/v13010140) (PMID:33478127) (PMCID:PMC7835746)

Schultz, V. et al. (2021) Zika virus infection leads to demyelination and axonal injury in mature CNS cultures. Viruses, 13(1), 91. (doi: 10.3390/v13010091) (PMID:33440758) (PMCID:PMC7827345)

2020

Dimitrov, Daniel and Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734 (2020) BingleSeq: A user-friendly R package for bulk and single-cell RNA-Seq data analysis. PeerJ, 8, e10469. (doi: 10.7717/peerj.10469) (PMID:33391870) (PMCID:PMC7761193)

Lau, Betty ORCID logoORCID: https://orcid.org/0000-0003-1382-9830, Kerr, Karen, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Nightingale, Katie, Antrobus, Robin, Suarez, Nicolas M., Stanton, Richard J., Wang, Eddie C., Weekes, Michael P. and Davison, Andrew J. ORCID logoORCID: https://orcid.org/0000-0002-4991-9128 (2020) Human cytomegalovirus long non-coding RNA1.2 suppresses extracellular release of the pro-inflammatory cytokine IL-6 by blocking NF-κB activation. Frontiers in Cellular and Infection Microbiology, 10, 361. (doi: 10.3389/fcimb.2020.00361) (PMID:32793512)

Sook Yuin Ho, J. et al. (2020) Hybrid gene origination creates human-virus chimeric proteins during infection. Cell, 181(7), 1502-1517.e23. (doi: 10.1016/j.cell.2020.05.035) (PMID:32559462) (PMCID:PMC7323901)

2019

McFarlane, S. et al. (2019) The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection. PLoS Pathogens, 15(3), e1007667. (doi: 10.1371/journal.ppat.1007667) (PMID:30901352) (PMCID:PMC6472835)

2018

Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734 and Veselkov, Kirill (2018) Bi-clustering of metabolic data using matrix factorization tools. Methods, 151, pp. 12-20. (doi: 10.1016/j.ymeth.2018.02.004) (PMID:29438828) (PMCID:PMC6297113)

Selinger, Martin, Wilkie, Gavin S., Tong, Lily, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Schnettler, Esther, Grubhoffer, Libor and Kohl, Alain ORCID logoORCID: https://orcid.org/0000-0002-1523-9458 (2018) Corrigendum: Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection. Journal of General Virology, 99(8), pp. 1147-1149. (doi: 10.1099/jgv.0.001109) (PMID:30067173)

Chauché, C., Nogales, A., Zhu, H., Goldfarb, D., Shanizza A.I., Ahmad, Gu, Q. ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Parrish, C.R., Martínez-Sobrido, L., Marshall, J.F. and Murcia, P.R. ORCID logoORCID: https://orcid.org/0000-0002-4352-394X (2018) Mammalian adaptation of an avian influenza A virus involves stepwise changes in NS1. Journal of Virology, 92(5), e01875-17. (doi: 10.1128/JVI.01875-17) (PMID:29237841) (PMCID:PMC5809720)

2017

Shaw, A. E. et al. (2017) Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses. PLoS Biology, 15(12), e2004086. (doi: 10.1371/journal.pbio.2004086) (PMID:29253856) (PMCID:PMC574750)

Bhome, R. et al. (2017) Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression. Aging, 9(12), pp. 2666-2694. (doi: 10.18632/aging.101355) (PMID:29283887)

Klymenko, T. et al. (2017) RNA-Seq analysis of differentiated keratinocytes reveals a massive response to late events during human papillomavirus 16 infection, including loss of epithelial barrier function. Journal of Virology, 91(24), e01001-17. (doi: 10.1128/JVI.01001-17) (PMID:29021401) (PMCID:PMC5709591)

Selinger, Martin, Wilkie, Gavin S., Tong, Lily, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Schnettler, Esther, Grubhoffer, Libor and Kohl, Alain ORCID logoORCID: https://orcid.org/0000-0002-1523-9458 (2017) Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection. Journal of General Virology, 98(8), pp. 2043-2060. (doi: 10.1099/jgv.0.000853) (PMID:28786780)

Dumas, M.-E. et al. (2017) Microbial-host co-metabolites are prodromal markers predicting phenotypic heterogeneity in behavior, obesity, and impaired glucose tolerance. Cell Reports, 20(1), pp. 136-148. (doi: 10.1016/j.celrep.2017.06.039) (PMID:28683308)

2016

Dumas, M.-E. et al. (2016) Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series. Genome Medicine, 8, 101. (doi: 10.1186/s13073-016-0352-6) (PMID:27716393) (PMCID:PMC5045612)

Ratinier, Maxime, Shaw, Andrew E., Barry, Gerald, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Di Gialleonardo, Luigina, Janowicz, Anna, Varela, Mariana, Randall, Richard E., Caporale, Marco and Palmarini, Massimo ORCID logoORCID: https://orcid.org/0000-0001-7007-4070 (2016) Bluetongue virus NS4 protein is an interferon antagonist and a determinant of virus virulence. Journal of Virology, 90(11), pp. 5427-5439. (doi: 10.1128/JVI.00422-16) (PMID:27009961) (PMCID:PMC4934764)

Orton, R.J. ORCID logoORCID: https://orcid.org/0000-0002-3389-4325, Gu, Q. ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Hughes, J. ORCID logoORCID: https://orcid.org/0000-0003-2556-2563, Maabar, M., Modha, S. ORCID logoORCID: https://orcid.org/0000-0002-8440-885X, Vattipally, Sreenu ORCID logoORCID: https://orcid.org/0000-0001-6673-4697, Wilkie, G.S. and Davison, A. ORCID logoORCID: https://orcid.org/0000-0002-4991-9128 (2016) Bioinformatics tools for analysing viral genomic data. Revue scientifique et technique (International Office of Epizootics), 35(1), pp. 241-285. (doi: 10.20506/rst.35.1.2432) (PMID:27217183)

2015

Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Ding, Yong-Sheng and Zhang, Tong-Liang (2015) An ensemble classifier based prediction of G-protein-coupled receptor classes in low homology. Neurocomputing, 154, pp. 110-118. (doi: 10.1016/j.neucom.2014.12.013)

Blomström, A.-L. et al. (2015) Transcriptome analysis reveals the host response to Schmallenberg virus in bovine cells and antagonistic effects of the NSs protein. BMC Genomics, 16, 324. (doi: 10.1186/s12864-015-1538-9) (PMID:25896169) (PMCID:PMC4404599)

2014

Hudson, Nicholas J., Baker, Michelle L., Hart, Nathan S., Wynne, James W., Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Huang, Zhiyong, Zhang, Guojie, Ingham, Aaron B., Wang, Linfa and Reverter, Antonio (2014) Sensory rewiring in an echolocator: genome-wide modification of retinogenic and auditory genes in the bat myotis davidii. G3: Genes, Genomes, Genetics, 4(10), pp. 1825-1835. (doi: 10.1534/g3.114.011262) (PMID:25096539) (PMCID:PMC4199690)

2011

Hudson, Nicholas J., Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Nagaraj, Shivashankar H., Ding, Yong-Sheng, Dalrymple, Brian P. and Reverter, Antonio (2011) Eukaryotic evolutionary transitions are associated with extreme codon bias in functionally-related proteins. PLoS ONE, 6(9), e25457. (doi: 10.1371/journal.pone.0025457) (PMID:21966531) (PMCID:PMC3179510)

Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Nagaraj, Shivashankar H., Hudson, Nicholas J., Dalrymple, Brian P. and Reverter, Antonio (2011) Genome-wide patterns of promoter sharing and co-expression in bovine skeletal muscle. BMC Genomics, 12, 23. (doi: 10.1186/1471-2164-12-23) (PMID:21226902) (PMCID:PMC3025955)

2010

Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Ding, Yong-Sheng and Zhang, Tong-Liang (2010) Prediction of G-protein-coupled receptor classes in low homology using Chou's pseudo amino acid composition with approximate entropy and hydrophobicity patterns. Protein and Peptide Letters, 17(5), pp. 559-567. (doi: 10.2174/092986610791112693)

Shen, Yi-Zhen, Ding, Yong-Sheng, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734 and Chou, Kuo-Chen (2010) Identifying the hub proteins from complicated membrane protein network systems. Medicinal Chemistry, 6(3), pp. 165-173. (doi: 10.2174/1573406411006030165) (PMID:20507268)

Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Ding, Yong-Sheng, Jiang, Xiao-Ying and Zhang, Tong-Liang (2010) Prediction of subcellular location apoptosis proteins with ensemble classifier and feature selection. Amino Acids, 38(4), pp. 975-983. (doi: 10.1007/s00726-008-0209-4) (PMID:19048186)

2009

Ding, Yong-Sheng, Zhang, Tong-Liang, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Zhao, Pei-Ying and Chou, Kuo-Chen (2009) Using maximum entropy model to predict protein secondary structure with single sequence. Protein and Peptide Letters, 16(5), pp. 552-560. (doi: 10.2174/092986609788167833) (PMID:19442235)

2008

Jiang, Xiaoying, Wei, Rong, Zhang, Tongliang and Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734 (2008) Using the concept of chous pseudo amino acid composition to predict apoptosis proteins subcellular location: an approach by approximate entropy. Protein and Peptide Letters, 15(4), pp. 392-396.

This list was generated on Tue Oct 14 01:12:35 2025 BST.
Jump to: Articles
Number of items: 45.

Articles

Petit, M. et al. (2025) Multi-omics analysis of SFTS virus infection in Rhipicephalus microplus cells reveals antiviral tick factors. Nature Communications, 16(1), 4732. (doi: 10.1038/s41467-025-59565-w) (PMID:40399277) (PMCID:PMC12095547)

Chen, Honglin, Charles, Philip D., Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Liberatori, Sabrina, Robertson, David L. ORCID logoORCID: https://orcid.org/0000-0001-6338-0221, Palmarini, Massimo ORCID logoORCID: https://orcid.org/0000-0001-7007-4070, Wilson, Sam J. ORCID logoORCID: https://orcid.org/0000-0002-6065-0895, Mohammed, Shabaz and Castello, Alfredo ORCID logoORCID: https://orcid.org/0000-0002-1499-4662 (2025) Omics analyses uncover host networks defining virus-permissive and -hostile cellular states. Molecular and Cellular Proteomics, 24(5), 100966. (doi: 10.1016/j.mcpro.2025.100966) (PMID:40204275) (PMCID:PMC12136899)

Faizo, Arwa Ali A, Bellward, Clare, Hernandez-Lopez, Hegel R., Stevenson, Andrew, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734 and Graham, Sheila ORCID logoORCID: https://orcid.org/0000-0002-7140-8279 (2025) The splicing factor kinase, SR protein kinase 1 (SRPK1) is essential for late events in the human papillomavirus life cycle. PLoS Pathogens, 21(4), e1012697. (doi: 10.1371/journal.ppat.1012697) (PMID:40203066) (PMCID:PMC12013937)

Ruscica, V. et al. (2024) XRN1 supplies free nucleotides to feed alphavirus replication. bioRxiv, (doi: 10.1101/2024.12.09.625895)

Herder, V. et al. (2024) Correlates of disease severity in bluetongue as a model of acute arbovirus infection. PLoS Pathogens, 20(8), e1012466. (doi: 10.1371/journal.ppat.1012466) (PMID:39150989) (PMCID:PMC11357116)

Herder, V. et al. (2024) A machine learning framework to identify the correlates of disease severity in acute arbovirus infection. bioRxiv, (doi: 10.1101/2024.02.23.581333) (PMID:PPR810635)

Meehan, G. R. et al. (2023) Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning. PLoS Pathogens, 19(11), e1011589. (doi: 10.1371/journal.ppat.1011589) (PMID:37934791) (PMCID:PMC10656012)

Cao, G. et al. (2023) Single-cell dissection of cervical cancer reveals key subsets of the tumor immune microenvironment. EMBO Journal, 42(16), e110757. (doi: 10.15252/embj.2022110757) (PMID:37427448)

Pinto, R. M. et al. (2023) BTN3A3 evasion promotes the zoonotic potential of influenza A viruses. Nature, 619(7969), pp. 338-347. (doi: 10.1038/s41586-023-06261-8) (PMID:37380775)

Hardy, A. et al. (2023) The timing and magnitude of the type I interferon response are correlated with disease tolerance in arbovirus infection. mBio, 14(3), e0010123. (doi: 10.1128/mbio.00101-23) (PMID:37097030) (PMCID:PMC10294695)

Chai, Haiting, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Robertson, David L. ORCID logoORCID: https://orcid.org/0000-0001-6338-0221 and Hughes, Joseph ORCID logoORCID: https://orcid.org/0000-0003-2556-2563 (2022) Defining the characteristics of interferon-alpha–stimulated human genes: insight from expression data and machine learning. GigaScience, 11, giac103. (doi: 10.1093/gigascience/giac103) (PMID:36399061) (PMCID:PMC9673497)

Chai, Haiting, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Hughes, Joseph ORCID logoORCID: https://orcid.org/0000-0003-2556-2563 and Robertson, David L. ORCID logoORCID: https://orcid.org/0000-0001-6338-0221 (2022) In silico prediction of HIV-1-host molecular interactions and their directionality. PLoS Computational Biology, 18(2), e1009720. (doi: 10.1371/journal.pcbi.1009720) (PMID:35134057) (PMCID:PMC8856524)

Amat, J. A.R. et al. (2021) Long-term adaptation following influenza A virus host shifts results in increased within-host viral fitness due to higher replication rates, broader dissemination within the respiratory epithelium and reduced tissue damage. PLoS Pathogens, 17(12), e1010174. (doi: 10.1371/journal.ppat.1010174) (PMID:34919598) (PMCID:PMC8735595)

Herder, V. et al. (2021) Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defences. PLoS Biology, 19(12), e3001065. (doi: 10.1371/journal.pbio.3001065) (PMID:34932557) (PMCID:PMC8765667)

Wickenhagen, A. et al. (2021) A prenylated dsRNA sensor protects against severe COVID-19. Science, 374(6567), eabj3624. (doi: 10.1126/science.abj3624) (PMID:34581622) (PMCID:PMC7612834)

Lau, B. et al. (2021) Human cytomegalovirus RNA2.7 is required for upregulating multiple cellular genes to promote cell motility and viral spread late in lytic infection. Journal of Virology, 95(20), e00698-21. (doi: 10.1128/JVI.00698-21) (PMID:34346763) (PMCID:PMC8475523)

Shaw, A. E. et al. (2021) The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. PLoS Biology, 19(9), e3001352. (doi: 10.1371/journal.pbio.3001352) (PMID:34491982) (PMCID:PMC8423302)

Baksmeier, C. et al. (2021) Modified recombinant human IgG1-Fc is superior to natural intravenous immunoglobulin at inhibiting immune-mediated demyelination. Immunology, 164(1), pp. 90-105. (doi: 10.1111/imm.13341) (PMID:33880776) (PMCID:PMC8358725)

Gallo, G. et al. (2021) Interactions of viral proteins from pathogenic and low or non-pathogenic orthohantaviruses with human type I interferon signaling. Viruses, 13(1), 140. (doi: 10.3390/v13010140) (PMID:33478127) (PMCID:PMC7835746)

Schultz, V. et al. (2021) Zika virus infection leads to demyelination and axonal injury in mature CNS cultures. Viruses, 13(1), 91. (doi: 10.3390/v13010091) (PMID:33440758) (PMCID:PMC7827345)

Dimitrov, Daniel and Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734 (2020) BingleSeq: A user-friendly R package for bulk and single-cell RNA-Seq data analysis. PeerJ, 8, e10469. (doi: 10.7717/peerj.10469) (PMID:33391870) (PMCID:PMC7761193)

Lau, Betty ORCID logoORCID: https://orcid.org/0000-0003-1382-9830, Kerr, Karen, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Nightingale, Katie, Antrobus, Robin, Suarez, Nicolas M., Stanton, Richard J., Wang, Eddie C., Weekes, Michael P. and Davison, Andrew J. ORCID logoORCID: https://orcid.org/0000-0002-4991-9128 (2020) Human cytomegalovirus long non-coding RNA1.2 suppresses extracellular release of the pro-inflammatory cytokine IL-6 by blocking NF-κB activation. Frontiers in Cellular and Infection Microbiology, 10, 361. (doi: 10.3389/fcimb.2020.00361) (PMID:32793512)

Sook Yuin Ho, J. et al. (2020) Hybrid gene origination creates human-virus chimeric proteins during infection. Cell, 181(7), 1502-1517.e23. (doi: 10.1016/j.cell.2020.05.035) (PMID:32559462) (PMCID:PMC7323901)

McFarlane, S. et al. (2019) The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection. PLoS Pathogens, 15(3), e1007667. (doi: 10.1371/journal.ppat.1007667) (PMID:30901352) (PMCID:PMC6472835)

Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734 and Veselkov, Kirill (2018) Bi-clustering of metabolic data using matrix factorization tools. Methods, 151, pp. 12-20. (doi: 10.1016/j.ymeth.2018.02.004) (PMID:29438828) (PMCID:PMC6297113)

Selinger, Martin, Wilkie, Gavin S., Tong, Lily, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Schnettler, Esther, Grubhoffer, Libor and Kohl, Alain ORCID logoORCID: https://orcid.org/0000-0002-1523-9458 (2018) Corrigendum: Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection. Journal of General Virology, 99(8), pp. 1147-1149. (doi: 10.1099/jgv.0.001109) (PMID:30067173)

Chauché, C., Nogales, A., Zhu, H., Goldfarb, D., Shanizza A.I., Ahmad, Gu, Q. ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Parrish, C.R., Martínez-Sobrido, L., Marshall, J.F. and Murcia, P.R. ORCID logoORCID: https://orcid.org/0000-0002-4352-394X (2018) Mammalian adaptation of an avian influenza A virus involves stepwise changes in NS1. Journal of Virology, 92(5), e01875-17. (doi: 10.1128/JVI.01875-17) (PMID:29237841) (PMCID:PMC5809720)

Shaw, A. E. et al. (2017) Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses. PLoS Biology, 15(12), e2004086. (doi: 10.1371/journal.pbio.2004086) (PMID:29253856) (PMCID:PMC574750)

Bhome, R. et al. (2017) Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression. Aging, 9(12), pp. 2666-2694. (doi: 10.18632/aging.101355) (PMID:29283887)

Klymenko, T. et al. (2017) RNA-Seq analysis of differentiated keratinocytes reveals a massive response to late events during human papillomavirus 16 infection, including loss of epithelial barrier function. Journal of Virology, 91(24), e01001-17. (doi: 10.1128/JVI.01001-17) (PMID:29021401) (PMCID:PMC5709591)

Selinger, Martin, Wilkie, Gavin S., Tong, Lily, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Schnettler, Esther, Grubhoffer, Libor and Kohl, Alain ORCID logoORCID: https://orcid.org/0000-0002-1523-9458 (2017) Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection. Journal of General Virology, 98(8), pp. 2043-2060. (doi: 10.1099/jgv.0.000853) (PMID:28786780)

Dumas, M.-E. et al. (2017) Microbial-host co-metabolites are prodromal markers predicting phenotypic heterogeneity in behavior, obesity, and impaired glucose tolerance. Cell Reports, 20(1), pp. 136-148. (doi: 10.1016/j.celrep.2017.06.039) (PMID:28683308)

Dumas, M.-E. et al. (2016) Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series. Genome Medicine, 8, 101. (doi: 10.1186/s13073-016-0352-6) (PMID:27716393) (PMCID:PMC5045612)

Ratinier, Maxime, Shaw, Andrew E., Barry, Gerald, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Di Gialleonardo, Luigina, Janowicz, Anna, Varela, Mariana, Randall, Richard E., Caporale, Marco and Palmarini, Massimo ORCID logoORCID: https://orcid.org/0000-0001-7007-4070 (2016) Bluetongue virus NS4 protein is an interferon antagonist and a determinant of virus virulence. Journal of Virology, 90(11), pp. 5427-5439. (doi: 10.1128/JVI.00422-16) (PMID:27009961) (PMCID:PMC4934764)

Orton, R.J. ORCID logoORCID: https://orcid.org/0000-0002-3389-4325, Gu, Q. ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Hughes, J. ORCID logoORCID: https://orcid.org/0000-0003-2556-2563, Maabar, M., Modha, S. ORCID logoORCID: https://orcid.org/0000-0002-8440-885X, Vattipally, Sreenu ORCID logoORCID: https://orcid.org/0000-0001-6673-4697, Wilkie, G.S. and Davison, A. ORCID logoORCID: https://orcid.org/0000-0002-4991-9128 (2016) Bioinformatics tools for analysing viral genomic data. Revue scientifique et technique (International Office of Epizootics), 35(1), pp. 241-285. (doi: 10.20506/rst.35.1.2432) (PMID:27217183)

Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Ding, Yong-Sheng and Zhang, Tong-Liang (2015) An ensemble classifier based prediction of G-protein-coupled receptor classes in low homology. Neurocomputing, 154, pp. 110-118. (doi: 10.1016/j.neucom.2014.12.013)

Blomström, A.-L. et al. (2015) Transcriptome analysis reveals the host response to Schmallenberg virus in bovine cells and antagonistic effects of the NSs protein. BMC Genomics, 16, 324. (doi: 10.1186/s12864-015-1538-9) (PMID:25896169) (PMCID:PMC4404599)

Hudson, Nicholas J., Baker, Michelle L., Hart, Nathan S., Wynne, James W., Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Huang, Zhiyong, Zhang, Guojie, Ingham, Aaron B., Wang, Linfa and Reverter, Antonio (2014) Sensory rewiring in an echolocator: genome-wide modification of retinogenic and auditory genes in the bat myotis davidii. G3: Genes, Genomes, Genetics, 4(10), pp. 1825-1835. (doi: 10.1534/g3.114.011262) (PMID:25096539) (PMCID:PMC4199690)

Hudson, Nicholas J., Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Nagaraj, Shivashankar H., Ding, Yong-Sheng, Dalrymple, Brian P. and Reverter, Antonio (2011) Eukaryotic evolutionary transitions are associated with extreme codon bias in functionally-related proteins. PLoS ONE, 6(9), e25457. (doi: 10.1371/journal.pone.0025457) (PMID:21966531) (PMCID:PMC3179510)

Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Nagaraj, Shivashankar H., Hudson, Nicholas J., Dalrymple, Brian P. and Reverter, Antonio (2011) Genome-wide patterns of promoter sharing and co-expression in bovine skeletal muscle. BMC Genomics, 12, 23. (doi: 10.1186/1471-2164-12-23) (PMID:21226902) (PMCID:PMC3025955)

Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Ding, Yong-Sheng and Zhang, Tong-Liang (2010) Prediction of G-protein-coupled receptor classes in low homology using Chou's pseudo amino acid composition with approximate entropy and hydrophobicity patterns. Protein and Peptide Letters, 17(5), pp. 559-567. (doi: 10.2174/092986610791112693)

Shen, Yi-Zhen, Ding, Yong-Sheng, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734 and Chou, Kuo-Chen (2010) Identifying the hub proteins from complicated membrane protein network systems. Medicinal Chemistry, 6(3), pp. 165-173. (doi: 10.2174/1573406411006030165) (PMID:20507268)

Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Ding, Yong-Sheng, Jiang, Xiao-Ying and Zhang, Tong-Liang (2010) Prediction of subcellular location apoptosis proteins with ensemble classifier and feature selection. Amino Acids, 38(4), pp. 975-983. (doi: 10.1007/s00726-008-0209-4) (PMID:19048186)

Ding, Yong-Sheng, Zhang, Tong-Liang, Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734, Zhao, Pei-Ying and Chou, Kuo-Chen (2009) Using maximum entropy model to predict protein secondary structure with single sequence. Protein and Peptide Letters, 16(5), pp. 552-560. (doi: 10.2174/092986609788167833) (PMID:19442235)

Jiang, Xiaoying, Wei, Rong, Zhang, Tongliang and Gu, Quan ORCID logoORCID: https://orcid.org/0000-0002-1201-6734 (2008) Using the concept of chous pseudo amino acid composition to predict apoptosis proteins subcellular location: an approach by approximate entropy. Protein and Peptide Letters, 15(4), pp. 392-396.

This list was generated on Tue Oct 14 01:12:35 2025 BST.

Supervision

  • Qin, Zhiling
    The host and viral factors influencing SARS-CoV2 infection and replication dynamics in culture models and human patient samples

Completed PhD students

2017-2022, H. Chai (co-supervised with David Robertson and Joseph Hughes)

Machine-learning-based identification of factors that influence molecular virus-host interactions

 

Completed MSc students

2025 C. Bates

2025 W. Sun

2024 L. Hao

2023 K. Zhang

2021 E. Agboraw

2021 C. Bellward (co-supervised with Shiela Graham)

2021 R. Moody (co-supervised with Shiela Graham)

2019 D. Dimitrov

2018 J. Lim

2017 G. Yang

 

Research datasets

Jump to: 2023 | 2021
Number of items: 3.

2023

Meehan, G. , Herder, V. , Allan, J., Huang, X., Kerr, K., Correa Mendonca, D. , Ilia, G., Wright, D. , Nomikou, K., Gu, Q. , Molina Arias, S., Hansmann, F., Hardas, A., Attipa, C., De Lorenzo, G. , Cowton, V., Upfold, N. , Palmalux, N., Brown, J., Barclay, W., Da Silva Filipe, A. , Furnon, W. , Patel, A. and Palmarini, M. (2023) Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning. [Data Collection]

2021

Wickenhagen, A., Sugrue, E. , Lytras, S., Kuchi, S., Noerenberg, M. , Turnbull, M. , Loney, C. , Herder, V., Allan, J., Jarmson, I., Cameron Ruiz, N., Varjak, M. , Pinto, R. , Lee, J. Y., Iselin, L., Palmalux, N., Stewart, D., Swingler, S., Greenwood, E. J. D., Crozier, T. W. M., Gu, Q. , Davies, E., Clohisey, S., Wang, B., Trindade Maranhã Costa, F., Santana, M. F., Carlos de Lima Ferreira, L., Murphy, L., Fawkes, A., Meynert, A., Grimes, G., ISARICC investigators, , Da Silva Filho, J. , Marti, M. , Hughes, J. , Stanton, R. J., Wang, E. C. Y., Ho, A. , Davis, I., Jarrett, R. , Castello, A. , Robertson, D. , Semple, M. G., Openshaw, P. J. M., Palmarini, M. , Lehner, P. J., Baillie, K., Rihn, S. and Wilson, S. (2021) A Prenylated dsRNA Sensor Protects Against Severe COVID-19. [Data Collection]

Shaw, A., Rihn, S. , Mollentze, N. , Wickenhagen, A., Stewart, D., Orton, R. , Kuchi, S., Bakshi, S., Collados Rodriguez, M. , Turnbull, M. , Busby, J., Gu, Q. , Smollett, K., Bamford, C., Sugrue, E. , Johnson, P. , Da Silva Filipe, A. , Castello, A. , Streicker, D. , Robertson, D. , Palmarini, M. and Wilson, S. (2021) The 'antiviral state' has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. [Data Collection] (Unpublished)

This list was generated on Tue Oct 14 17:31:32 2025 BST.