Professor Pasquale Maffia

  • Professor of Cardiovascular Immunology (Immunology & Infection)
  • Professor (School of Cardiovascular & Metabolic Health)

telephone: 01413307142
email: Pasquale.Maffia@glasgow.ac.uk
pronouns: He/him/his

RB423 Level B4, Iii - Gbrc, University Place, Glasgow G12 8TA

Import to contacts

ORCID iDhttps://orcid.org/0000-0003-3926-4225

Biography

I am currently a Professor of Cardiovascular Immunology at the School of Infection & Immunity and the School of Cardiovascular & Metabolic Health at the University of Glasgow (UK). I also serve as the School of Infection & Immunity International Lead.

I am an elected fellow of the Royal Society of Biology, the British Pharmacological Society, and the European Society of Cardiology.

I serve as Chair of the International Union of Basic and Clinical Pharmacology (IUPHAR) Immunopharmacology Committee, as Elected Vice-President and Chair of the Engagement Committee of the British Pharmacological Society (BPS), as Vice-Chair of the International Union of Immunological Societies (IUIS) Immunotherapy Committee, and as a Nucleus Member of the European Society of Cardiology (ESC) Working Group on Atherosclerosis & Vascular Biology. I also serve on the Executive Committee of the British Atherosclerosis Society (BAS), on the Fellowship Committee of the British Heart Foundation (BHF), and as Vice-Chair of the Heart Research UK (HRUK) Translational Research Medical Review Panel.

I am a Deputy Editor of Cardiovascular Research, Associate Editor of Pharmacological Research, Editor in Chief of Frontiers for Young Minds (Health Section), and Editorial Board Member of a number of journals including the British Journal of Pharmacology, and Scientific Reports.

I have a major interest in the immune response in cardiovascular disease. Current research activities address the study, imaging, and targeting of cellular and molecular immune mechanisms involved in the pathophysiology of atherosclerosis, hypertension, and heart failure. I have authored over 110 scientific papers in peer-reviewed journals including Nature Genetics, Nature Reviews Immunology, Immunity, European Heart Journal, Circulation, Circulation Research, Blood, and JCI.

Find out more about my Public Engagement work

Research interests

My major interest is the immune response in cardiovascular diseases. Current research activities address the study, imaging, and targeting of immune and inflammatory mechanisms involved in the pathophysiology of atherosclerosis, hypertension and heart failure.

Immune responses play a key role in cardiovascular diseases (Eur Heart J. 2019). We have developed techniques to track antigen-presenting cells and antigen presentation in the development of vascular immune response (Arterioscler Thromb Vasc Biol. 2012; Circulation 2014; Cardiovasc Res. 2020). We have been amongst the first to apply multiphoton microscopy in experimental atherosclerosis (Circulation 2007) and stroke (Stroke 2011) with the aim to define the kinetics and anatomical location of the T cell-antigen presenting cell interactions that underlie vascular immune response in real-time in vivo (Immunity 2015). We have developed surface-enhanced Raman spectroscopy for multiplexing molecular imaging of vascular inflammation (Theranostics 2018). The ultimate goal is to develop new modalities for imaging vascular inflammation and deliver immuno-modulatory treatments directly to the vessel wall (ACS Appl Mater Interfaces 2020). Similarly, I am contributing to the elucidation of immune mechanisms in hypertension (Circ Res. 2020; Circulation 2020; Nat Genet. 2021; JCI 2022) and heart failure (Cardiovasc Res. 2022).

My research programme has been well-funded externally by the British Heart Foundation (BHF), the European Commission, the Engineering and Physical Sciences Research Council (EPSRC), the Erasmus+ International Credit Mobility, the European Society of Cardiology (ESC), Global Challenges Research Funds, Medical Research Scotland (MRS), Scottish Funding Council (SFC) and Canon Medical Systems.

Collaborations are established with researchers nationally (Guzik, Edinburgh; Garside, Brewer, Graham, McInnes, Kurowska-Stolarska, Otto, Sattar, Pellicori, Cleland, Glasgow; Monaco, Oxford; Tomaszewski, Manchester; Graham, Strathclyde; Mallat, Jorgensen, Cambridge; Yarwood, Heriot-Watt) and internationally (Decuzzi, IIT; Olofsson, Karolinska; Peter, Baker Institute; Owolabi, Ibadan; Harrison, Vanderbilt; Habenicht, LMU; Lembo, Carnevale, NeuroMed; Norata, Milan; Bruzzese, Ialenti, Naples; Pasterkamp, Utrecht).

Publications

List by: Type | Date

Jump to: 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1996
Number of items: 112.

2023

Wiejak, J., Murphy, F. A., Maffia, P. and Yarwood, S. J. (2023) Vascular smooth muscle cells enhance immune/vascular interplay in a 3-cell model of vascular inflammation. Scientific Reports, 13(1), 15889. (doi: 10.1038/s41598-023-43221-8) (PMID:37741880) (PMCID:PMC10517978)

Peh, H. Y., Gurgone, D. and Maffia, P. (2023) Immunopharmacology sessions at the 19th World Congress of Basic and Clinical Pharmacology 2023. Pharmacological Research, (doi: 10.1016/j.phrs.2023.106911) (Early Online Publication)

Clément, M. et al. (2023) CD31 signaling promotes the detachment at the uropod of extravasating neutrophils allowing their migration to sites of inflammation. eLife, 12, e84752. (doi: 10.7554/eLife.84752) (PMID:37549051) (PMCID:PMC10431918)

Iaconelli, A., Cuthbert, J., Kazmi, S., Maffia, P. , Clark, A. L., Cleland, J. G.F. and Pellicori, P. (2023) Inferior vena cava diameter is associated with prognosis in patients with chronic heart failure independent of tricuspid regurgitation velocity. Clinical Research in Cardiology, 112(8), pp. 1077-1086. (doi: 10.1007/s00392-023-02178-4) (PMID:36894788) (PMCID:PMC10359207)

Iaconelli, A., Pellicori, P. , Caiazzo, E., Rezig, A. O. M. , Bruzzese, D., Maffia, P. and Cleland, J. G. F. (2023) Implanted haemodynamic telemonitoring devices to guide management of heart failure: a review and meta-analysis of randomised trials. Clinical Research in Cardiology, 112(8), pp. 1007-1019. (doi: 10.1007/s00392-022-02104-0) (PMID:36241896) (PMCID:PMC9568893)

Iaconelli, A. et al. (2023) Coronary revascularization for heart failure with coronary artery disease: a systematic review and meta-analysis of randomized trials. European Journal of Heart Failure, 25(7), pp. 1170-1175. (doi: 10.1002/ejhf.2911) (PMID:37211964)

Siedlinski, M. et al. (2023) Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure. European Heart Journal, 44(23), pp. 2114-2125. (doi: 10.1093/eurheartj/ehad101) (PMID:36972688) (PMCID:PMC10281555)

2022

Pugliese, N. R., Pellicori, P. , Filidei, F., De Biase, N., Maffia, P. , Guzik, T. J., Masi, S., Taddei, S. and Cleland, J. G.F. (2022) Inflammatory pathways in heart failure with preserved left ventricular ejection fraction: implications for future interventions. Cardiovascular Research, 118(18), pp. 3536-3555. (doi: 10.1093/cvr/cvac133) (PMID:36004819) (PMCID:PMC9897694)

Wiejak, J., Luchowska-Stańska, U., Wang, P., Zhou, J., Maffia, P. , Morgan, D., Barker, G. and Yarwood, S. J. (2022) Protein interaction, cytotoxic, transcriptomic and proteomic responses to structurally distinct EPAC1 activators in HUVECs. Scientific Reports, 12, 16505. (doi: 10.1038/s41598-022-20607-8) (PMID:36198739) (PMCID:PMC9534843)

Szczepaniak, P. et al. (2022) Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mechanism. Journal of Clinical Investigation, 132(13), e149117. (doi: 10.1172/JCI149117) (PMID:35617030) (PMCID:PMC9246378)

Wainwright, C. L. et al. (2022) Future directions for the discovery of natural product-derived immunomodulating drugs. Pharmacological Research, 177, 106076. (doi: 10.1016/j.phrs.2022.106076) (PMID:35074524)

Caiazzo, E., Rezig, A. O.M. , Bruzzese, D., Ialenti, A., Cicala, C., Cleland, J. G.F. , Guzik, T. J., Maffia, P. and Pellicori, P. (2022) Systemic administration of glucocorticoids, cardiovascular complications and mortality in patients hospitalised with COVID-19, SARS, MERS or influenza: a systematic review and meta-analysis of randomised trials. Pharmacological Research, 176, 106053. (doi: 10.1016/j.phrs.2021.106053) (PMID:34979235) (PMCID:PMC8719379)

2021

Murray, E. C. , Nosalski, R., MacRitchie, N., Tomaszewski, M., Maffia, P. , Harrison, D. G. and Guzik, T. J. (2021) Therapeutic targeting of inflammation in hypertension: from novel mechanisms to translational perspective. Cardiovascular Research, 117(13), pp. 2589-2609. (doi: 10.1093/cvr/cvab330) (PMID:34698811)

MacRitchie, N., Noonan, J., Guzik, T. J. and Maffia, P. (2021) Molecular imaging of cardiovascular inflammation. British Journal of Pharmacology, 178(21), pp. 4216-4245. (doi: 10.1111/bph.15654) (PMID:34378206)

Maffia, P. , Antoniades, C., Ahluwalia, A. and Cirino, G. (2021) Molecular imaging - the first visual themed issue published in the British Journal of Pharmacology. British Journal of Pharmacology, 178(21), pp. 4213-4215. (doi: 10.1111/bph.15632) (PMID:34664273)

MacRitchie, N., Di Francesco, V., Ferreira, M. F. M. M., Guzik, T. J., Decuzzi, P. and Maffia, P. (2021) Nanoparticle theranostics in cardiovascular inflammation. Seminars in Immunology, 56, 101536. (doi: 10.1016/j.smim.2021.101536) (PMID:34862118) (PMCID:PMC8811479)

Olowoyo, P., Popoola, F., Yaria, J., Akinyemi, R., Maffia, P. and Owolabi, M. O. (2021) Strategies for reducing non-communicable diseases in Africa. Pharmacological Research, 170, 105736. (doi: 10.1016/j.phrs.2021.105736) (PMID:34147659) (PMCID:PMC8800856)

Mikolajczyk, T. P., Szczepaniak, P., Vidler, F., Maffia, P. , Graham, G. J. and Guzik, T. J. (2021) Role of inflammatory chemokines in hypertension. Pharmacology and Therapeutics, 223, 107799. (doi: 10.1016/j.pharmthera.2020.107799) (PMID:33359600)

Eales, J. M. et al. (2021) Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney. Nature Genetics, 53(5), pp. 630-637. (doi: 10.1038/s41588-021-00835-w) (PMID:33958779)

Maiuri, M. C. and Maffia, P. (2021) Cellular metabolism and diseases. British Journal of Pharmacology, 178(10), pp. 2031-2033. (doi: 10.1111/bph.15355) (PMID:33932230)

Sharma, S. et al. (2021) Periodontal therapy and treatment of hypertension – alternative to the pharmacological approach. A systematic review and meta-analysis. Pharmacological Research, 166, 105511. (doi: 10.1016/j.phrs.2021.105511) (PMID:33617973)

MacRitchie, N. and Maffia, P. (2021) Light sheet fluorescence microscopy for quantitative 3D imaging of vascular remodelling. Cardiovascular Research, 117(2), pp. 348-350. (doi: 10.1093/cvr/cvaa131) (PMID:32386306) (PMCID:PMC7820857)

2020

Charla, E., Mercer, J. , Maffia, P. and Nicklin, S. (2020) Extracellular vesicle signalling in atherosclerosis. Cellular Signalling, 75, 109751. (doi: 10.1016/j.cellsig.2020.109751) (PMID:32860954) (PMCID:PMC7534042)

Nosalski, R., Mikolajczyk, T., Siedlinski, M., Saju, B., Koziol, J., Maffia, P. and Guzik, T.J. (2020) Nox1/4 inhibition exacerbates age dependent perivascular inflammation and fibrosis in a model of spontaneous hypertension. Pharmacological Research, 161, 105235. (doi: 10.1016/j.phrs.2020.105235) (PMID:33131726) (PMCID:PMC8316606)

Henderson, I., Caiazzo, E., McSharry, C., Guzik, T. J. and Maffia, P. (2020) Why do some asthma patients respond poorly to glucocorticoid therapy? Pharmacological Research, 160, 105189. (doi: 10.1016/j.phrs.2020.105189) (PMID:32911071) (PMCID:PMC7672256)

Sabir, S. R., Thomson, E. C. , Guzik, T. J., D’Acquisto, F. and Maffia, P. (2020) COVID-19: the new immune challenge. Frontiers for Young Minds, 8, 582971. (doi: 10.3389/frym.2020.582971)

Di Francesco, V., Gurgone, D., Palomba, R., Ferreira, M. F. M. M., Catelani, T., Cervadoro, A., Maffia, P. and Decuzzi, P. (2020) Modulating lipoprotein transcellular transport and atherosclerotic plaque formation in apoe-/- mice via nanoformulated lipid-methotrexate conjugates. ACS Applied Materials and Interfaces, 12(34), pp. 37943-37956. (doi: 10.1021/acsami.0c12202) (PMID:32805983) (PMCID:PMC7453397)

Guzik, T. J. et al. (2020) COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovascular Research, 116(10), pp. 1666-1687. (doi: 10.1093/cvr/cvaa106) (PMID:32352535) (PMCID:PMC7197627)

MacRitchie, N., Frleta-Gilchrist, M., Sugiyama, A., Lawton, T., McInnes, I. B. and Maffia, P. (2020) Molecular Imaging of Inflammation - current and emerging technologies for diagnosis and treatment. Pharmacology and Therapeutics, 211, 107550. (doi: 10.1016/j.pharmthera.2020.107550)

Tavares, L. P., Peh, H. Y., Tan, W. S. D., Pahima, H., Maffia, P. , Tiligada, E. and Levi-Schaffer, F. (2020) Granulocyte-targeted therapies for airway diseases. Pharmacological Research, 157, 104881. (doi: 10.1016/j.phrs.2020.104881)

Harding, S. D. et al. (2020) The IUPHAR guide to immunopharmacology: connecting immunology and pharmacology. Immunology, 160(1), pp. 10-23. (doi: 10.1111/imm.13175) (PMID:32020584) (PMCID:PMC7160657)

Milling, S. , Spedding, M. and Maffia, P. (2020) Guide to Immunopharmacology: a database to boost immunology education, research and therapy. Immunology, 160(1), pp. 1-2. (doi: 10.1111/imm.13201)

Siedlinski, M. et al. (2020) White blood cells and blood pressure: a Mendelian randomization study. Circulation, 141(16), pp. 1307-1317. (doi: 10.1161/CIRCULATIONAHA.119.045102) (PMID:32148083) (PMCID:PMC7176352)

Nosalski, R. et al. (2020) T cell-derived miRNA-214 mediates perivascular fibrosis in hypertension. Circulation Research, 126, pp. 988-1003. (doi: 10.1161/CIRCRESAHA.119.315428) (PMID:32065054) (PMCID:PMC7147427)

Gurgone, D., McShane, L. , McSharry, C., Guzik, T. J. and Maffia, P. (2020) Cytokines at the interplay between asthma and atherosclerosis? Frontiers in Pharmacology, 11, 166. (doi: 10.3389/fphar.2020.00166)

MacRitchie, N. et al. (2020) The aorta can act as site of naïve CD4+ T cell priming. Cardiovascular Research, 116(2), pp. 306-316. (doi: 10.1093/cvr/cvz102) (PMID:30980670)

2019

Eales, J. M. et al. (2019) The human Y chromosome exerts pleiotropic effects on susceptibility to atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 39(11), pp. 2386-2401. (doi: 10.1161/ATVBAHA.119.312405) (PMID:31644355) (PMCID:PMC6818981)

Sagan, A. et al. (2019) T cells are dominant population in human abdominal aortic aneurysms and their infiltration in the perivascular tissue correlates with disease severity. Frontiers in Immunology, 10, 1979. (doi: 10.3389/fimmu.2019.01979) (PMID:31552015) (PMCID:PMC6736986)

MacRitchie, N. and Maffia, P. (2019) Resolvin E1 for reducing vascular calcification. Cardiovascular Research, 115(10), pp. 1457-1459. (doi: 10.1093/cvr/cvz101) (PMID:30989192) (PMCID:PMC6648334)

Maffia, P. and Guzik, T. J. (2019) When, where and how to target vascular inflammation in the post-CANTOS era? European Heart Journal, 40(30), pp. 2492-2494. (doi: 10.1093/eurheartj/ehz133) (PMID:30929007) (PMCID:PMC6685316)

McShane, L. , Tabas, I., Lemke, G., Kurowska-Stolarska, M. and Maffia, P. (2019) TAM receptors in cardiovascular disease. Cardiovascular Research, 115(5), pp. 1286-1295. (doi: 10.1093/cvr/cvz100) (PMID:30980657) (PMCID:PMC6587925)

Mikolajczyk, T. P. et al. (2019) 1,2,3,4,6 penta-O -galloyl-β-D-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. British Journal of Pharmacology, 176(12), pp. 1951-1965. (doi: 10.1111/bph.14583) (PMID:30658013) (PMCID:PMC6534792)

Noonan, J., Grassia, G., MacRitchie, N., Garside, P. , Guzik, T. J., Bradshaw, A. C. and Maffia, P. (2019) A novel triple-cell two-dimensional model to study immune-vascular interplay in atherosclerosis. Frontiers in Immunology, 10, 849. (doi: 10.3389/fimmu.2019.00849) (PMID:31068936) (PMCID:PMC6491724)

Kritikou, E., van der Heijden, T., Swart, M., van Duijn, J., Slütter, B., Wezel, A., Smeets, H. J., Maffia, P. , Kuiper, J. and Bot, I. (2019) Hypercholesterolemia induces a mast cell–CD4+ T cell interaction in atherosclerosis. Journal of Immunology, 202(5), pp. 1531-1539. (doi: 10.4049/jimmunol.1800648) (PMID:30683705)

Maffia, P. , Mantovani, A. and Spedding, M. (2019) Scientists on the spot: the Guide to Immunopharmacology as a new resource for the cardiovascular community. Cardiovascular Research, 115(1), e5-e6. (doi: 10.1093/cvr/cvy296) (PMID:30576437)

McShane, L. , Sage, A. P. and Maffia, P. (2019) Inflammation and immunity in vascular diseases. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 229-238. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_21)

2018

Harding, S. D., Faccenda, E., Southan, C., Maffia, P. and Davies, J. A. (2018) A new guide to immunopharmacology. Nature Reviews Immunology, 18(12), p. 729. (doi: 10.1038/s41577-018-0079-2) (PMID:30327546)

Cicha, I. et al. (2018) From design to the clinic: practical guidelines for translating cardiovascular nanomedicine. Cardiovascular Research, 114(13), pp. 1714-1727. (doi: 10.1093/cvr/cvy219) (PMID:30165574) (PMCID:PMC6198738)

Guzik, T. J. et al. (2018) What matters in Cardiovascular Research? Scientific discovery driving clinical delivery. Cardiovascular Research, 114(12), pp. 1565-1568. (doi: 10.1093/cvr/cvy214)

Loperena, R. et al. (2018) Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide. Cardiovascular Research, 114(11), pp. 1547-1563. (doi: 10.1093/cvr/cvy112) (PMID:29800237) (PMCID:PMC6106108)

Maffia, P. , Nosalski, R. and Guzik, T. J. (2018) Monocytes M(MP)aking way for T cell vascular infiltration. Circulation Research, 123(6), pp. 638-640. (doi: 10.1161/CIRCRESAHA.118.313668) (PMID:30355241)

Cole, J. E., Park, I., Ahern, D., Kassiteridi, C., Danso Abeam, D., Goddard, M., Green, P., Maffia, P. and Monaco, C. (2018) Immune cell census in murine atherosclerosis: cytometry by time of flight illuminates vascular myeloid cell diversity. Cardiovascular Research, 114(10), pp. 1360-1371. (doi: 10.1093/cvr/cvy109) (PMID:29726984) (PMCID:PMC6054192)

MacRitchie, N. and Maffia, P. (2018) "Blow my mind(in)" - Mindin neutralization for the prevention of atherosclerosis? Clinical Science, 132(14), pp. 1509-1512. (doi: 10.1042/CS20180358) (PMID:30037838)

Maffia, P. (2018) Why we should reward peer reviewers. Cardiovascular Research, 114(5), e30-e31. (doi: 10.1093/cvr/cvy050) (PMID:29590390)

Grassia, G., MacRitchie, N. and Maffia, P. (2018) Immune mechanisms in atherosclerosis and potential for immunomodulatory therapies. In: Riccardi, C., Levi-Schaffer, F. and Tiligada, E. (eds.) Immunopharmacology and Inflammation. Springer: Cham, pp. 211-224. ISBN 9783319776576 (doi: 10.1007/978-3-319-77658-3_9)

MacRitchie, N., Grassia, G., Noonan, J., Garside, P. , Graham, D. and Maffia, P. (2018) Molecular imaging of atherosclerosis: spotlight on Raman spectroscopy and surface-enhanced Raman scattering. Heart, 104(6), pp. 460-467. (doi: 10.1136/heartjnl-2017-311447) (PMID:29061690) (PMCID:PMC5861389)

Noonan, J. et al. (2018) In vivo multiplex molecular imaging of vascular inflammation using surface-enhanced Raman spectroscopy. Theranostics, 8(22), pp. 6195-6209. (doi: 10.7150/thno.28665) (PMID:30613292) (PMCID:PMC6299693)

2017

Maffia, P. and Cirino, G. (2017) Targeting inflammation to reduce cardiovascular disease risk. British Journal of Pharmacology, 174(22), pp. 3895-3897. (doi: 10.1111/bph.14039) (PMID:29080212) (PMCID:PMC5659995)

Welsh, P. , Grassia, G., Botha, S., Sattar, N. and Maffia, P. (2017) Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? British Journal of Pharmacology, 174(22), pp. 3898-3913. (doi: 10.1111/bph.13818) (PMID:28409825) (PMCID:PMC5660005)

Yin, C., Mohanta, S., Maffia, P. and Habenicht, A. J.R. (2017) Editorial: tertiary lymphoid organs (TLOs): powerhouses of disease immunity. Frontiers in Immunology, 8, 228. (doi: 10.3389/fimmu.2017.00228) (PMID:28321222) (PMCID:PMC5337484)

Maffia, P. , Döring, Y., Biessen, E. A.L. and Mallat, Z. (2017) Commentary: Indoleamine 2,3-dioxygenase-expressing aortic plasmacytoid dendritic cells protect against atherosclerosis by induction of regulatory T cells. Frontiers in Immunology, 10(8), 140. (doi: 10.3389/fimmu.2017.00140) (PMID:28243244) (PMCID:PMC5304905)

2016

Hughes, C. E. , Benson, R. A. , Bedaj, M. and Maffia, P. (2016) Antigen-presenting cells and antigen presentation in tertiary lymphoid organs. Frontiers in Immunology, 7, 481. (doi: 10.3389/fimmu.2016.00481) (PMID:27872626) (PMCID:PMC5097899)

Srikakulapu, P. et al. (2016) Artery tertiary lymphoid organs control multi-layered territorialized atherosclerosis B cell responses in aged ApoE-/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology, 36, pp. 1174-1185. (doi: 10.1161/ATVBAHA.115.306983) (PMID:27102965) (PMCID:PMC4894775)

Scales, H. E. , Ierna, M., Smith, K. M., Ross, K., Meiklejohn, G. R., Patterson-Kane, J. C., McInnes, I. B., Brewer, J. M. , Garside, P. and Maffia, P. (2016) Assessment of murine collagen-induced arthritis by longitudinal non-invasive duplexed molecular optical imaging. Rheumatology, 55(3), pp. 564-572. (doi: 10.1093/rheumatology/kev361) (PMID:26475798)

2015

Wu, J., Grassia, G., Cambrook, H., Ialenti, A., MacRitchie, N., Carberry, J., Wadsworth, R. M., Lawrence, C., Kennedy, S. and Maffia, P. (2015) Perivascular mast cells regulate vein graft neointimal formation and remodeling. PeerJ, 3, e1192. (doi: 10.7717/peerj.1192) (PMID:26312183) (PMCID:PMC4548472)

Collins, P. E., Grassia, G., Colleran, A., Kiely, P. A., Ialenti, A., Maffia, P. and Carmody, R. J. (2015) Mapping the interaction of B cell Leukemia 3 (BCL-3) and nuclear factor κB (NF-κB) p50 identifies a BCL-3-mimetic anti-inflammatory peptide. Journal of Biological Chemistry, 290(25), pp. 15687-15696. (doi: 10.1074/jbc.M115.643700) (PMID:25922067) (PMCID:PMC4505479)

Hu, D. et al. (2015) Artery tertiary lymphoid organs control aorta immunity and protect against atherosclerosis via vascular smooth muscle cell lymphotoxin β receptors. Immunity, 42(6), pp. 1100-1115. (doi: 10.1016/j.immuni.2015.05.015) (PMID:26084025) (PMCID:PMC4678289)

2014

Xiao, Q. et al. (2014) Matrix metalloproteinase-8 promotes vascular smooth muscle cell proliferation and neointima formation. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(1), pp. 90-98. (doi: 10.1161/ATVBAHA.113.301418) (PMID:24158518)

Maddaluno, M., MacRitchie, N., Grassia, G., Ialenti, A., Butcher, J. P., Garside, P. , Brewer, J. M. and Maffia, P. (2014) Murine aortic smooth muscle cells acquire, though fail to present exogenous protein antigens on major histocompatibility complex class II molecules. BioMed Research International(949845), (doi: 10.1155/2014/949845) (PMID:25136640) (PMCID:PMC4127268)

Sage, A. P. et al. (2014) MHC class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity. Circulation, 130(16), pp. 1363-1373. (doi: 10.1161/CIRCULATIONAHA.114.011090) (PMID:25223984) (PMCID:PMC4428652)

2013

Kennedy, S. , Wu, J., Wadsworth, R.M., Lawrence, C.E. and Maffia, P. (2013) Mast cells and vascular diseases. Pharmacology and Therapeutics, 138(1), pp. 53-65. (doi: 10.1016/j.pharmthera.2013.01.001)

Grassia, G., MacRitchie, N., Platt, A., Brewer, J. , Garside, P. and Maffia, P. (2013) Plasmacytoid dendritic cells: biomarkers or potential therapeutic targets in atherosclerosis? Pharmacology and Therapeutics, 137(2), pp. 172-182. (doi: 10.1016/j.pharmthera.2012.10.001) (PMID:23059425)

Maiuri, M.C., Grassia, G., Platt, A., Carnuccio, R., Ialenti, A. and Maffia, P. (2013) Macrophage autophagy in atherosclerosis. Mediators of Inflammation, 2013, Art. 584715. (doi: 10.1155/2013/584715)

2012

MacRitchie, N. et al. (2012) Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology, 32(11), pp. 2569-2579. (doi: 10.1161/ATVBAHA.112.251314)

Blair, P. and Maffia, P. (2012) Revisited role of B cells in atherosclerosis. Pharmaceutica Analytica Acta, 3(8), 1000174. (doi: 10.4172/2153-2435.1000174)

Gibson, V.B. et al. (2012) A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo. Blood, 119(11), pp. 2545-2551. (doi: 10.1182/blood-2011-09-378356) (PMID:22271449) (PMCID:PMC3398133)

Maddaluno, M. et al. (2012) Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching. PLoS ONE, 7(10), e47464. (doi: 10.1371/journal.pone.0047464) (PMID:23077623) (PMCID:PMC3471825)

McQueenie, R., Stevenson, R., Benson, R. , MacRitchie, N., McInnes, I. , Maffia, P. , Faulds, K., Graham, D., Brewer, J. and Garside, P. (2012) Detection of inflammation in vivo by surface-enhanced raman scattering provides higher sensitivity than conventional fluorescence imaging. Analytical Chemistry, 84(14), pp. 5968-5975. (doi: 10.1021/ac3006445)

2011

Ialenti, A. et al. (2011) Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries. Arteriosclerosis, Thrombosis, and Vascular Biology, 31(11), pp. 2448-2454. (doi: 10.1161/ATVBAHA.111.230078) (PMID:21852559)

Patakas, A., Platt, A. M., Butcher, J. P., Maffia, P. , McInnes, I. B. , Brewer, J. M. , Garside, P. and Benson, R. A. (2011) Putative existence of reciprocal dialogue between Tfh and B cells and its impact on infectious and autoimmune disease. Immunology Letters, 138(1), pp. 38-46. (doi: 10.1016/j.imlet.2011.03.002) (PMID:21419798)

Fumagalli, S. et al. (2011) In vivo real-time multiphoton imaging of t lymphocytes in the mouse brain after experimental stroke. Stroke, 42(5), pp. 1429-1436. (doi: 10.1161/STROKEAHA.110.603704)

2010

Grassia, G. et al. (2010) The IkB kinase inhibitor nuclear factor-kB essential modulator–binding domain peptide for inhibition of balloon injury-induced neointimal formation. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(12), pp. 2458-2466. (doi: 10.1161/ATVBAHA.110.215467) (PMID:20930169)

Ortolano, F., Maffia, P. , Dever, G., Rodolico, G. , Millington, O.R., De Simoni, M.G., Brewer, J.M. , Bushell, T.J., Garside, P. and Carswell, H.V. (2010) Advances in imaging of new targets for pharmacological intervention in stroke: real-time tracking of T-cells in the ischaemic brain. British Journal of Pharmacology, 159(4), pp. 808-811. (doi: 10.1111/j.1476-5381.2009.00527.x) (PMID:20015295) (PMCID:PMC2829206)

Millington, O. R., Brewer, J. M. , Garside, P. and Maffia, P. (2010) Imaging interactions between the immune and cardiovascular systems in vivo by multiphoton microscopy. In: Marelli-Berg, F. M. and Nourshargh, S. (eds.) T-Cell Trafficking: Methods and Protocols. Series: Methods in Molecular Biology, 616 (616). Humana Press Inc, pp. 193-206. ISBN 9781607614609 (doi: 10.1007/978-1-60761-461-6_13)

2009

Grassia, G., Maddaluno, M., Guglielmotti, A., Mangano, G., Biondi, G., Maffia, P. and Ialenti, A. (2009) The anti-inflammatory agent bindarit inhibits neointima formation in both rats and hyperlipidaemic mice. Cardiovascular Research, 84(3), pp. 485-493. (doi: 10.1093/cvr/cvp238) (PMID:19592568) (PMCID:PMC2777949)

D'Emmanuele di Villa Bianca, R., Sorrentino, R., Maffia, P. , Mirone, F., Imbimbo, C., Fusco, F., De Palma, R., Ignarro, L.J. and Cirino, G. (2009) Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation. Proceedings of the National Academy of Sciences of the United States of America, 106(11), pp. 4513-4518. (doi: 10.1073/pnas.0807974105)

Ortolano, F. et al. (2009) Imaging T-cell movement in the brain during experimental cerebral malaria. Parasite Immunology, 31(3), 147-150 (4). (doi: 10.1111/j.1365-3024.2008.01090.x)

2007

Maffia, P. , Zinselmeyer, B.H., Ialenti, A., Kennedy, S. , Baker, A.H., McInnes, I., Brewer, J.M. and Garside, P. (2007) Multiphoton microscopy for 3-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115(11), E326-E328. (doi: 10.1161/CIRCULATIONAHA.106.658492) (PMID:17372180)

2006

Maffia, P. , Grassia, G., Di Meglio, P., Carnuccio, R., Berrino, L., Garside, P. , Ianaro, A. and Ialenti, A. (2006) Neutralization of interleukin-18 inhibits neointimal formation in a rat model of vascular injury. Circulation, 114, pp. 430-437. (doi: 10.1161/CIRCULATIONAHA.105.602714) (PMID:16864728)

Ialenti, A., Di Meglio, P., Grassia, G., Maffia, P. , Di Rosa, M., Lanzetta, R., Molinaro, A., Silipo, A., Grant, W. and Ianaro, A. (2006) A novel lipid A fromHalomonas magadiensis inhibits enteric LPS-induced human monocyte activation. European Journal of Immunology, 36(2), pp. 354-360. (doi: 10.1002/eji.200535305) (PMID:16365914)

2005

Morello, S., Vellecco, V., Roviezzo, F., Maffia, P. , Cuzzocrea, S., Cirino, G. and Cicala, C. (2005) A protective role for proteinase activated receptor 2 in airways of lipopolysaccharide-treated rats. Biochemical Pharmacology, 71(1-2), pp. 223-230. (doi: 10.1016/j.bcp.2005.10.016) (PMID:16300746)

Corea, G., Fattorusso, E., Lanzotti, V., Di Meglio, P., Maffia, P. , Grassia, G., Ialenti, A. and Ianaro, A. (2005) Discovery and biological evaluation of the novel naturally occurring diterpene pepluanone as antiinflammatory agent. Journal of Medicinal Chemistry, 48(22), pp. 7055-7062. (doi: 10.1021/jm050321r) (PMID:16250665)

Ialenti, A., Grassia, G., Di Meglio, P., Maffia, P. , Di Rosa, M. and Ianaro, A. (2005) Mechanism of the anti-inflammatory effect of thiazolidinediones: relationship with the glucocorticoid pathway. Molecular Pharmacology, 67(5), pp. 1620-1628. (doi: 10.1124/mol.104.004895) (PMID:15684043)

Ialenti, A., Di Meglio, P., D'Acquisto, F., Pisano, B., Maffia, P. , Grassia, G., Di Rosa, M. and Ianaro, A. (2005) Inhibition of cyclooxygenase-2 gene expression by the heat shock response in J774 murine macrophages. European Journal of Pharmacology, 509(2-3), pp. 89-96. (doi: 10.1016/j.ejphar.2004.10.052) (PMID:15733543)

2004

Maffia, P. , Brewer, J. M. , Gracie, J. A., Ianaro, A., Leung, B. P., Mitchell, P. J., Smith, K. M., McInnes, I. B. and Garside, P. (2004) Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173(1), pp. 151-156. (doi: 10.4049/jimmunol.173.1.151) (PMID:15210769)

Cuzzocrea, S. et al. (2004) Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-γ, reduces acute inflammation. European Journal of Pharmacology, 483(1), pp. 79-93. (doi: 10.1016/j.ejphar.2003.10.056) (PMID:14709329)

2003

Lippolis, L., Sorrentino, R., Popolo, A., Maffia, P. , Nasti, C., Villa Bianca, R. d.’E. d., Marzocco, S., Autore, G. and Pinto, A. (2003) Time course of vascular reactivity to contracting and relaxing agents after endothelial denudation by balloon angioplasty in rat carotid artery. Atherosclerosis, 171(2), pp. 171-179. (doi: 10.1016/j.atherosclerosis.2003.07.012) (PMID:14644385)

Ianaro, A., Maffia, P. , Cuzzocrea, S., Mazzon, E., Santoro, M. G., Di Rosa, M. and Ialenti, A. (2003) 2-Cyclopenten-1-one and prostaglandin J2 reduce restenosis after balloon angioplasty in rats: role of NF-κB. FEBS Letters, 553(1-2), pp. 21-27. (doi: 10.1016/S0014-5793(03)00873-1) (PMID:14550540)

Ianaro, A., Ialenti, A., Maffia, P. , Di Meglio, P., Di Rosa, M. and Santoro, M. G. (2003) Anti-inflammatory activity of 15-deoxy- 12,14-PGJ2 and 2-cyclopenten-1-one: role of the heat shock response. Molecular Pharmacology, 64(1), pp. 85-93. (doi: 10.1124/mol.64.1.85) (PMID:12815164)

Ianaro, A., Maffia, P. , Rosa, M. and Ialenti, A. (2003) Cyclopentenone prostaglandins as anti-inflammatory agents: A novel therapeutic strategy? Current Medicinal Chemistry: Anti-Inflammatory and Anti-Allergy Agents, 2(2), pp. 85-93. (doi: 10.2174/1568014033483851)

2002

Mascolo, N., Izzo, A. A., Ligresti, A., Costagliola, A., Pinto, L., Cascio, M. G., Maffia, P. , Cecio, A., Capasso, F. and Di Marzo, V. (2002) The endocannabinoid system and the molecular basis of paralytic ileus in mice. FASEB Journal, (doi: 10.1096/fj.02-0338fje) (PMID:12397089)

Borrelli, F., Izzo, A.A., Di Carlo, G., Maffia, P. , Russo, A., Maiello, F.M., Capasso, F. and Mascolo, N. (2002) Effect of a propolis extract and caffeic acid phenethyl ester on formation of aberrant crypt foci and tumors in the rat colon. Fitoterapia, 73(Supl 1), S38-S43. (doi: 10.1016/S0367-326X(02)00189-2) (PMID:12495708)

Borrelli, F., Maffia, P. , Pinto, L., Ianaro, A., Russo, A., Capasso, F. and Ialenti, A. (2002) Phytochemical compounds involved in the anti-inflammatory effect of propolis extract. Fitoterapia, 73(Supl 1), S53-S63. (doi: 10.1016/S0367-326X(02)00191-0) (PMID:12495710)

Maffia, P. , Ianaro, A., Sorrentino, R., Lippolis, L., Maiello, F. M., del Soldato, P., Ialenti, A. and Cirino, G. (2002) Beneficial effects of NO-releasing derivative of flurbiprofen (HCT-1026) in rat model of vascular injury and restenosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 22(2), pp. 263-267. (PMID:11834526)

2001

Ianaro, A., Ialenti, A., Maffia, P. , Pisano, B. and Di Rosa, M. (2001) Role of cyclopentenone prostaglandins in rat carrageenin pleurisy. FEBS Letters, 508(1), pp. 61-66. (doi: 10.1016/S0014-5793(01)03035-6) (PMID:11707269)

D'Acquisto, F., Ianaro, A., Ialenti, A., Maffia, P. , Maiuri, M. and Carnuccio, R. (2001) Transcription factor decoy oligodeoxynucleotides to nuclear factor-κB inhibit reverse passive Arthus reaction in rat. Naunyn-Schmiedeberg's Archives of Pharmacology, 364(5), pp. 422-429. (doi: 10.1007/s002100100472) (PMID:11692225)

Ianaro, A., Ialenti, A., Maffia, P. , Pisano, B. and Di Rosa, M. (2001) HSF1/hsp72 pathway as an endogenous anti-inflammatory system. FEBS Letters, 499(3), pp. 239-244. (doi: 10.1016/S0014-5793(01)02569-8) (PMID:11423124)

Ialenti, A. et al. (2001) Synthesis of novel anti-inflammatory peptides derived from the amino-acid sequence of the bioactive protein SV-IV. European Journal of Biochemistry, 268(12), pp. 3399-3406. (doi: 10.1046/j.1432-1327.2001.02236.x) (PMID:11422369)

2000

Ialenti, A., Ianaro, A., Maffia, P. , Sautebin, L. and Di Rosa, M. (2000) Nitric oxide inhibits leucocyte migration in carrageenin-induced rat pleurisy. Inflammation Research, 49(8), pp. 411-417. (doi: 10.1007/s000110050609) (PMID:11028758)

Ianaro, A., Ialenti, A., Maffia, P. , Sautebin, L., Rombolà, L., Carnuccio, R., Iuvone, T., D'Acquisto, F. and Di Rosa, M. (2000) Anti-inflammatory activity of macrolide antibiotics. Journal of Pharmacology and Experimental Therapeutics, 292(1), pp. 156-163. (PMID:10604943)

1996

Costantino, V., Fattorusso, E., Mangoni, A., Rosa, M. D., Ianaro, A. and Maffia, P. (1996) Glycolipids from sponges. IV. Immunomodulating glycosyl ceramides from the marine sponge agelas dispar. Tetrahedron, 52(5), pp. 1573-1578. (doi: 10.1016/0040-4020(95)00986-8)

Caliendo, G., Greco, G., Grieco, P., Perissutti, E., Santagada, V., Ialenti, A., Maffia, P. , Albrizio, S. and Santini, A. (1996) Synthesis and antinociceptive activity of peptides related to interleukin-1β193–195 Lys-Pro-Thr. Biopolymers, 40(5), pp. 479-484. (doi: 10.1002/(SICI)1097-0282(1996)40:5<479::AID-BIP5>3.0.CO;2-T) (PMID:9062070)

This list was generated on Thu Nov 30 20:42:57 2023 GMT.
Jump to: Articles | Book Sections
Number of items: 112.

Articles

Wiejak, J., Murphy, F. A., Maffia, P. and Yarwood, S. J. (2023) Vascular smooth muscle cells enhance immune/vascular interplay in a 3-cell model of vascular inflammation. Scientific Reports, 13(1), 15889. (doi: 10.1038/s41598-023-43221-8) (PMID:37741880) (PMCID:PMC10517978)

Peh, H. Y., Gurgone, D. and Maffia, P. (2023) Immunopharmacology sessions at the 19th World Congress of Basic and Clinical Pharmacology 2023. Pharmacological Research, (doi: 10.1016/j.phrs.2023.106911) (Early Online Publication)

Clément, M. et al. (2023) CD31 signaling promotes the detachment at the uropod of extravasating neutrophils allowing their migration to sites of inflammation. eLife, 12, e84752. (doi: 10.7554/eLife.84752) (PMID:37549051) (PMCID:PMC10431918)

Iaconelli, A., Cuthbert, J., Kazmi, S., Maffia, P. , Clark, A. L., Cleland, J. G.F. and Pellicori, P. (2023) Inferior vena cava diameter is associated with prognosis in patients with chronic heart failure independent of tricuspid regurgitation velocity. Clinical Research in Cardiology, 112(8), pp. 1077-1086. (doi: 10.1007/s00392-023-02178-4) (PMID:36894788) (PMCID:PMC10359207)

Iaconelli, A., Pellicori, P. , Caiazzo, E., Rezig, A. O. M. , Bruzzese, D., Maffia, P. and Cleland, J. G. F. (2023) Implanted haemodynamic telemonitoring devices to guide management of heart failure: a review and meta-analysis of randomised trials. Clinical Research in Cardiology, 112(8), pp. 1007-1019. (doi: 10.1007/s00392-022-02104-0) (PMID:36241896) (PMCID:PMC9568893)

Iaconelli, A. et al. (2023) Coronary revascularization for heart failure with coronary artery disease: a systematic review and meta-analysis of randomized trials. European Journal of Heart Failure, 25(7), pp. 1170-1175. (doi: 10.1002/ejhf.2911) (PMID:37211964)

Siedlinski, M. et al. (2023) Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure. European Heart Journal, 44(23), pp. 2114-2125. (doi: 10.1093/eurheartj/ehad101) (PMID:36972688) (PMCID:PMC10281555)

Pugliese, N. R., Pellicori, P. , Filidei, F., De Biase, N., Maffia, P. , Guzik, T. J., Masi, S., Taddei, S. and Cleland, J. G.F. (2022) Inflammatory pathways in heart failure with preserved left ventricular ejection fraction: implications for future interventions. Cardiovascular Research, 118(18), pp. 3536-3555. (doi: 10.1093/cvr/cvac133) (PMID:36004819) (PMCID:PMC9897694)

Wiejak, J., Luchowska-Stańska, U., Wang, P., Zhou, J., Maffia, P. , Morgan, D., Barker, G. and Yarwood, S. J. (2022) Protein interaction, cytotoxic, transcriptomic and proteomic responses to structurally distinct EPAC1 activators in HUVECs. Scientific Reports, 12, 16505. (doi: 10.1038/s41598-022-20607-8) (PMID:36198739) (PMCID:PMC9534843)

Szczepaniak, P. et al. (2022) Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mechanism. Journal of Clinical Investigation, 132(13), e149117. (doi: 10.1172/JCI149117) (PMID:35617030) (PMCID:PMC9246378)

Wainwright, C. L. et al. (2022) Future directions for the discovery of natural product-derived immunomodulating drugs. Pharmacological Research, 177, 106076. (doi: 10.1016/j.phrs.2022.106076) (PMID:35074524)

Caiazzo, E., Rezig, A. O.M. , Bruzzese, D., Ialenti, A., Cicala, C., Cleland, J. G.F. , Guzik, T. J., Maffia, P. and Pellicori, P. (2022) Systemic administration of glucocorticoids, cardiovascular complications and mortality in patients hospitalised with COVID-19, SARS, MERS or influenza: a systematic review and meta-analysis of randomised trials. Pharmacological Research, 176, 106053. (doi: 10.1016/j.phrs.2021.106053) (PMID:34979235) (PMCID:PMC8719379)

Murray, E. C. , Nosalski, R., MacRitchie, N., Tomaszewski, M., Maffia, P. , Harrison, D. G. and Guzik, T. J. (2021) Therapeutic targeting of inflammation in hypertension: from novel mechanisms to translational perspective. Cardiovascular Research, 117(13), pp. 2589-2609. (doi: 10.1093/cvr/cvab330) (PMID:34698811)

MacRitchie, N., Noonan, J., Guzik, T. J. and Maffia, P. (2021) Molecular imaging of cardiovascular inflammation. British Journal of Pharmacology, 178(21), pp. 4216-4245. (doi: 10.1111/bph.15654) (PMID:34378206)

Maffia, P. , Antoniades, C., Ahluwalia, A. and Cirino, G. (2021) Molecular imaging - the first visual themed issue published in the British Journal of Pharmacology. British Journal of Pharmacology, 178(21), pp. 4213-4215. (doi: 10.1111/bph.15632) (PMID:34664273)

MacRitchie, N., Di Francesco, V., Ferreira, M. F. M. M., Guzik, T. J., Decuzzi, P. and Maffia, P. (2021) Nanoparticle theranostics in cardiovascular inflammation. Seminars in Immunology, 56, 101536. (doi: 10.1016/j.smim.2021.101536) (PMID:34862118) (PMCID:PMC8811479)

Olowoyo, P., Popoola, F., Yaria, J., Akinyemi, R., Maffia, P. and Owolabi, M. O. (2021) Strategies for reducing non-communicable diseases in Africa. Pharmacological Research, 170, 105736. (doi: 10.1016/j.phrs.2021.105736) (PMID:34147659) (PMCID:PMC8800856)

Mikolajczyk, T. P., Szczepaniak, P., Vidler, F., Maffia, P. , Graham, G. J. and Guzik, T. J. (2021) Role of inflammatory chemokines in hypertension. Pharmacology and Therapeutics, 223, 107799. (doi: 10.1016/j.pharmthera.2020.107799) (PMID:33359600)

Eales, J. M. et al. (2021) Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney. Nature Genetics, 53(5), pp. 630-637. (doi: 10.1038/s41588-021-00835-w) (PMID:33958779)

Maiuri, M. C. and Maffia, P. (2021) Cellular metabolism and diseases. British Journal of Pharmacology, 178(10), pp. 2031-2033. (doi: 10.1111/bph.15355) (PMID:33932230)

Sharma, S. et al. (2021) Periodontal therapy and treatment of hypertension – alternative to the pharmacological approach. A systematic review and meta-analysis. Pharmacological Research, 166, 105511. (doi: 10.1016/j.phrs.2021.105511) (PMID:33617973)

MacRitchie, N. and Maffia, P. (2021) Light sheet fluorescence microscopy for quantitative 3D imaging of vascular remodelling. Cardiovascular Research, 117(2), pp. 348-350. (doi: 10.1093/cvr/cvaa131) (PMID:32386306) (PMCID:PMC7820857)

Charla, E., Mercer, J. , Maffia, P. and Nicklin, S. (2020) Extracellular vesicle signalling in atherosclerosis. Cellular Signalling, 75, 109751. (doi: 10.1016/j.cellsig.2020.109751) (PMID:32860954) (PMCID:PMC7534042)

Nosalski, R., Mikolajczyk, T., Siedlinski, M., Saju, B., Koziol, J., Maffia, P. and Guzik, T.J. (2020) Nox1/4 inhibition exacerbates age dependent perivascular inflammation and fibrosis in a model of spontaneous hypertension. Pharmacological Research, 161, 105235. (doi: 10.1016/j.phrs.2020.105235) (PMID:33131726) (PMCID:PMC8316606)

Henderson, I., Caiazzo, E., McSharry, C., Guzik, T. J. and Maffia, P. (2020) Why do some asthma patients respond poorly to glucocorticoid therapy? Pharmacological Research, 160, 105189. (doi: 10.1016/j.phrs.2020.105189) (PMID:32911071) (PMCID:PMC7672256)

Sabir, S. R., Thomson, E. C. , Guzik, T. J., D’Acquisto, F. and Maffia, P. (2020) COVID-19: the new immune challenge. Frontiers for Young Minds, 8, 582971. (doi: 10.3389/frym.2020.582971)

Di Francesco, V., Gurgone, D., Palomba, R., Ferreira, M. F. M. M., Catelani, T., Cervadoro, A., Maffia, P. and Decuzzi, P. (2020) Modulating lipoprotein transcellular transport and atherosclerotic plaque formation in apoe-/- mice via nanoformulated lipid-methotrexate conjugates. ACS Applied Materials and Interfaces, 12(34), pp. 37943-37956. (doi: 10.1021/acsami.0c12202) (PMID:32805983) (PMCID:PMC7453397)

Guzik, T. J. et al. (2020) COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovascular Research, 116(10), pp. 1666-1687. (doi: 10.1093/cvr/cvaa106) (PMID:32352535) (PMCID:PMC7197627)

MacRitchie, N., Frleta-Gilchrist, M., Sugiyama, A., Lawton, T., McInnes, I. B. and Maffia, P. (2020) Molecular Imaging of Inflammation - current and emerging technologies for diagnosis and treatment. Pharmacology and Therapeutics, 211, 107550. (doi: 10.1016/j.pharmthera.2020.107550)

Tavares, L. P., Peh, H. Y., Tan, W. S. D., Pahima, H., Maffia, P. , Tiligada, E. and Levi-Schaffer, F. (2020) Granulocyte-targeted therapies for airway diseases. Pharmacological Research, 157, 104881. (doi: 10.1016/j.phrs.2020.104881)

Harding, S. D. et al. (2020) The IUPHAR guide to immunopharmacology: connecting immunology and pharmacology. Immunology, 160(1), pp. 10-23. (doi: 10.1111/imm.13175) (PMID:32020584) (PMCID:PMC7160657)

Milling, S. , Spedding, M. and Maffia, P. (2020) Guide to Immunopharmacology: a database to boost immunology education, research and therapy. Immunology, 160(1), pp. 1-2. (doi: 10.1111/imm.13201)

Siedlinski, M. et al. (2020) White blood cells and blood pressure: a Mendelian randomization study. Circulation, 141(16), pp. 1307-1317. (doi: 10.1161/CIRCULATIONAHA.119.045102) (PMID:32148083) (PMCID:PMC7176352)

Nosalski, R. et al. (2020) T cell-derived miRNA-214 mediates perivascular fibrosis in hypertension. Circulation Research, 126, pp. 988-1003. (doi: 10.1161/CIRCRESAHA.119.315428) (PMID:32065054) (PMCID:PMC7147427)

Gurgone, D., McShane, L. , McSharry, C., Guzik, T. J. and Maffia, P. (2020) Cytokines at the interplay between asthma and atherosclerosis? Frontiers in Pharmacology, 11, 166. (doi: 10.3389/fphar.2020.00166)

MacRitchie, N. et al. (2020) The aorta can act as site of naïve CD4+ T cell priming. Cardiovascular Research, 116(2), pp. 306-316. (doi: 10.1093/cvr/cvz102) (PMID:30980670)

Eales, J. M. et al. (2019) The human Y chromosome exerts pleiotropic effects on susceptibility to atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 39(11), pp. 2386-2401. (doi: 10.1161/ATVBAHA.119.312405) (PMID:31644355) (PMCID:PMC6818981)

Sagan, A. et al. (2019) T cells are dominant population in human abdominal aortic aneurysms and their infiltration in the perivascular tissue correlates with disease severity. Frontiers in Immunology, 10, 1979. (doi: 10.3389/fimmu.2019.01979) (PMID:31552015) (PMCID:PMC6736986)

MacRitchie, N. and Maffia, P. (2019) Resolvin E1 for reducing vascular calcification. Cardiovascular Research, 115(10), pp. 1457-1459. (doi: 10.1093/cvr/cvz101) (PMID:30989192) (PMCID:PMC6648334)

Maffia, P. and Guzik, T. J. (2019) When, where and how to target vascular inflammation in the post-CANTOS era? European Heart Journal, 40(30), pp. 2492-2494. (doi: 10.1093/eurheartj/ehz133) (PMID:30929007) (PMCID:PMC6685316)

McShane, L. , Tabas, I., Lemke, G., Kurowska-Stolarska, M. and Maffia, P. (2019) TAM receptors in cardiovascular disease. Cardiovascular Research, 115(5), pp. 1286-1295. (doi: 10.1093/cvr/cvz100) (PMID:30980657) (PMCID:PMC6587925)

Mikolajczyk, T. P. et al. (2019) 1,2,3,4,6 penta-O -galloyl-β-D-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. British Journal of Pharmacology, 176(12), pp. 1951-1965. (doi: 10.1111/bph.14583) (PMID:30658013) (PMCID:PMC6534792)

Noonan, J., Grassia, G., MacRitchie, N., Garside, P. , Guzik, T. J., Bradshaw, A. C. and Maffia, P. (2019) A novel triple-cell two-dimensional model to study immune-vascular interplay in atherosclerosis. Frontiers in Immunology, 10, 849. (doi: 10.3389/fimmu.2019.00849) (PMID:31068936) (PMCID:PMC6491724)

Kritikou, E., van der Heijden, T., Swart, M., van Duijn, J., Slütter, B., Wezel, A., Smeets, H. J., Maffia, P. , Kuiper, J. and Bot, I. (2019) Hypercholesterolemia induces a mast cell–CD4+ T cell interaction in atherosclerosis. Journal of Immunology, 202(5), pp. 1531-1539. (doi: 10.4049/jimmunol.1800648) (PMID:30683705)

Maffia, P. , Mantovani, A. and Spedding, M. (2019) Scientists on the spot: the Guide to Immunopharmacology as a new resource for the cardiovascular community. Cardiovascular Research, 115(1), e5-e6. (doi: 10.1093/cvr/cvy296) (PMID:30576437)

Harding, S. D., Faccenda, E., Southan, C., Maffia, P. and Davies, J. A. (2018) A new guide to immunopharmacology. Nature Reviews Immunology, 18(12), p. 729. (doi: 10.1038/s41577-018-0079-2) (PMID:30327546)

Cicha, I. et al. (2018) From design to the clinic: practical guidelines for translating cardiovascular nanomedicine. Cardiovascular Research, 114(13), pp. 1714-1727. (doi: 10.1093/cvr/cvy219) (PMID:30165574) (PMCID:PMC6198738)

Guzik, T. J. et al. (2018) What matters in Cardiovascular Research? Scientific discovery driving clinical delivery. Cardiovascular Research, 114(12), pp. 1565-1568. (doi: 10.1093/cvr/cvy214)

Loperena, R. et al. (2018) Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide. Cardiovascular Research, 114(11), pp. 1547-1563. (doi: 10.1093/cvr/cvy112) (PMID:29800237) (PMCID:PMC6106108)

Maffia, P. , Nosalski, R. and Guzik, T. J. (2018) Monocytes M(MP)aking way for T cell vascular infiltration. Circulation Research, 123(6), pp. 638-640. (doi: 10.1161/CIRCRESAHA.118.313668) (PMID:30355241)

Cole, J. E., Park, I., Ahern, D., Kassiteridi, C., Danso Abeam, D., Goddard, M., Green, P., Maffia, P. and Monaco, C. (2018) Immune cell census in murine atherosclerosis: cytometry by time of flight illuminates vascular myeloid cell diversity. Cardiovascular Research, 114(10), pp. 1360-1371. (doi: 10.1093/cvr/cvy109) (PMID:29726984) (PMCID:PMC6054192)

MacRitchie, N. and Maffia, P. (2018) "Blow my mind(in)" - Mindin neutralization for the prevention of atherosclerosis? Clinical Science, 132(14), pp. 1509-1512. (doi: 10.1042/CS20180358) (PMID:30037838)

Maffia, P. (2018) Why we should reward peer reviewers. Cardiovascular Research, 114(5), e30-e31. (doi: 10.1093/cvr/cvy050) (PMID:29590390)

MacRitchie, N., Grassia, G., Noonan, J., Garside, P. , Graham, D. and Maffia, P. (2018) Molecular imaging of atherosclerosis: spotlight on Raman spectroscopy and surface-enhanced Raman scattering. Heart, 104(6), pp. 460-467. (doi: 10.1136/heartjnl-2017-311447) (PMID:29061690) (PMCID:PMC5861389)

Noonan, J. et al. (2018) In vivo multiplex molecular imaging of vascular inflammation using surface-enhanced Raman spectroscopy. Theranostics, 8(22), pp. 6195-6209. (doi: 10.7150/thno.28665) (PMID:30613292) (PMCID:PMC6299693)

Maffia, P. and Cirino, G. (2017) Targeting inflammation to reduce cardiovascular disease risk. British Journal of Pharmacology, 174(22), pp. 3895-3897. (doi: 10.1111/bph.14039) (PMID:29080212) (PMCID:PMC5659995)

Welsh, P. , Grassia, G., Botha, S., Sattar, N. and Maffia, P. (2017) Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? British Journal of Pharmacology, 174(22), pp. 3898-3913. (doi: 10.1111/bph.13818) (PMID:28409825) (PMCID:PMC5660005)

Yin, C., Mohanta, S., Maffia, P. and Habenicht, A. J.R. (2017) Editorial: tertiary lymphoid organs (TLOs): powerhouses of disease immunity. Frontiers in Immunology, 8, 228. (doi: 10.3389/fimmu.2017.00228) (PMID:28321222) (PMCID:PMC5337484)

Maffia, P. , Döring, Y., Biessen, E. A.L. and Mallat, Z. (2017) Commentary: Indoleamine 2,3-dioxygenase-expressing aortic plasmacytoid dendritic cells protect against atherosclerosis by induction of regulatory T cells. Frontiers in Immunology, 10(8), 140. (doi: 10.3389/fimmu.2017.00140) (PMID:28243244) (PMCID:PMC5304905)

Hughes, C. E. , Benson, R. A. , Bedaj, M. and Maffia, P. (2016) Antigen-presenting cells and antigen presentation in tertiary lymphoid organs. Frontiers in Immunology, 7, 481. (doi: 10.3389/fimmu.2016.00481) (PMID:27872626) (PMCID:PMC5097899)

Srikakulapu, P. et al. (2016) Artery tertiary lymphoid organs control multi-layered territorialized atherosclerosis B cell responses in aged ApoE-/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology, 36, pp. 1174-1185. (doi: 10.1161/ATVBAHA.115.306983) (PMID:27102965) (PMCID:PMC4894775)

Scales, H. E. , Ierna, M., Smith, K. M., Ross, K., Meiklejohn, G. R., Patterson-Kane, J. C., McInnes, I. B., Brewer, J. M. , Garside, P. and Maffia, P. (2016) Assessment of murine collagen-induced arthritis by longitudinal non-invasive duplexed molecular optical imaging. Rheumatology, 55(3), pp. 564-572. (doi: 10.1093/rheumatology/kev361) (PMID:26475798)

Wu, J., Grassia, G., Cambrook, H., Ialenti, A., MacRitchie, N., Carberry, J., Wadsworth, R. M., Lawrence, C., Kennedy, S. and Maffia, P. (2015) Perivascular mast cells regulate vein graft neointimal formation and remodeling. PeerJ, 3, e1192. (doi: 10.7717/peerj.1192) (PMID:26312183) (PMCID:PMC4548472)

Collins, P. E., Grassia, G., Colleran, A., Kiely, P. A., Ialenti, A., Maffia, P. and Carmody, R. J. (2015) Mapping the interaction of B cell Leukemia 3 (BCL-3) and nuclear factor κB (NF-κB) p50 identifies a BCL-3-mimetic anti-inflammatory peptide. Journal of Biological Chemistry, 290(25), pp. 15687-15696. (doi: 10.1074/jbc.M115.643700) (PMID:25922067) (PMCID:PMC4505479)

Hu, D. et al. (2015) Artery tertiary lymphoid organs control aorta immunity and protect against atherosclerosis via vascular smooth muscle cell lymphotoxin β receptors. Immunity, 42(6), pp. 1100-1115. (doi: 10.1016/j.immuni.2015.05.015) (PMID:26084025) (PMCID:PMC4678289)

Xiao, Q. et al. (2014) Matrix metalloproteinase-8 promotes vascular smooth muscle cell proliferation and neointima formation. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(1), pp. 90-98. (doi: 10.1161/ATVBAHA.113.301418) (PMID:24158518)

Maddaluno, M., MacRitchie, N., Grassia, G., Ialenti, A., Butcher, J. P., Garside, P. , Brewer, J. M. and Maffia, P. (2014) Murine aortic smooth muscle cells acquire, though fail to present exogenous protein antigens on major histocompatibility complex class II molecules. BioMed Research International(949845), (doi: 10.1155/2014/949845) (PMID:25136640) (PMCID:PMC4127268)

Sage, A. P. et al. (2014) MHC class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity. Circulation, 130(16), pp. 1363-1373. (doi: 10.1161/CIRCULATIONAHA.114.011090) (PMID:25223984) (PMCID:PMC4428652)

Kennedy, S. , Wu, J., Wadsworth, R.M., Lawrence, C.E. and Maffia, P. (2013) Mast cells and vascular diseases. Pharmacology and Therapeutics, 138(1), pp. 53-65. (doi: 10.1016/j.pharmthera.2013.01.001)

Grassia, G., MacRitchie, N., Platt, A., Brewer, J. , Garside, P. and Maffia, P. (2013) Plasmacytoid dendritic cells: biomarkers or potential therapeutic targets in atherosclerosis? Pharmacology and Therapeutics, 137(2), pp. 172-182. (doi: 10.1016/j.pharmthera.2012.10.001) (PMID:23059425)

Maiuri, M.C., Grassia, G., Platt, A., Carnuccio, R., Ialenti, A. and Maffia, P. (2013) Macrophage autophagy in atherosclerosis. Mediators of Inflammation, 2013, Art. 584715. (doi: 10.1155/2013/584715)

MacRitchie, N. et al. (2012) Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology, 32(11), pp. 2569-2579. (doi: 10.1161/ATVBAHA.112.251314)

Blair, P. and Maffia, P. (2012) Revisited role of B cells in atherosclerosis. Pharmaceutica Analytica Acta, 3(8), 1000174. (doi: 10.4172/2153-2435.1000174)

Gibson, V.B. et al. (2012) A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo. Blood, 119(11), pp. 2545-2551. (doi: 10.1182/blood-2011-09-378356) (PMID:22271449) (PMCID:PMC3398133)

Maddaluno, M. et al. (2012) Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching. PLoS ONE, 7(10), e47464. (doi: 10.1371/journal.pone.0047464) (PMID:23077623) (PMCID:PMC3471825)

McQueenie, R., Stevenson, R., Benson, R. , MacRitchie, N., McInnes, I. , Maffia, P. , Faulds, K., Graham, D., Brewer, J. and Garside, P. (2012) Detection of inflammation in vivo by surface-enhanced raman scattering provides higher sensitivity than conventional fluorescence imaging. Analytical Chemistry, 84(14), pp. 5968-5975. (doi: 10.1021/ac3006445)

Ialenti, A. et al. (2011) Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries. Arteriosclerosis, Thrombosis, and Vascular Biology, 31(11), pp. 2448-2454. (doi: 10.1161/ATVBAHA.111.230078) (PMID:21852559)

Patakas, A., Platt, A. M., Butcher, J. P., Maffia, P. , McInnes, I. B. , Brewer, J. M. , Garside, P. and Benson, R. A. (2011) Putative existence of reciprocal dialogue between Tfh and B cells and its impact on infectious and autoimmune disease. Immunology Letters, 138(1), pp. 38-46. (doi: 10.1016/j.imlet.2011.03.002) (PMID:21419798)

Fumagalli, S. et al. (2011) In vivo real-time multiphoton imaging of t lymphocytes in the mouse brain after experimental stroke. Stroke, 42(5), pp. 1429-1436. (doi: 10.1161/STROKEAHA.110.603704)

Grassia, G. et al. (2010) The IkB kinase inhibitor nuclear factor-kB essential modulator–binding domain peptide for inhibition of balloon injury-induced neointimal formation. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(12), pp. 2458-2466. (doi: 10.1161/ATVBAHA.110.215467) (PMID:20930169)

Ortolano, F., Maffia, P. , Dever, G., Rodolico, G. , Millington, O.R., De Simoni, M.G., Brewer, J.M. , Bushell, T.J., Garside, P. and Carswell, H.V. (2010) Advances in imaging of new targets for pharmacological intervention in stroke: real-time tracking of T-cells in the ischaemic brain. British Journal of Pharmacology, 159(4), pp. 808-811. (doi: 10.1111/j.1476-5381.2009.00527.x) (PMID:20015295) (PMCID:PMC2829206)

Grassia, G., Maddaluno, M., Guglielmotti, A., Mangano, G., Biondi, G., Maffia, P. and Ialenti, A. (2009) The anti-inflammatory agent bindarit inhibits neointima formation in both rats and hyperlipidaemic mice. Cardiovascular Research, 84(3), pp. 485-493. (doi: 10.1093/cvr/cvp238) (PMID:19592568) (PMCID:PMC2777949)

D'Emmanuele di Villa Bianca, R., Sorrentino, R., Maffia, P. , Mirone, F., Imbimbo, C., Fusco, F., De Palma, R., Ignarro, L.J. and Cirino, G. (2009) Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation. Proceedings of the National Academy of Sciences of the United States of America, 106(11), pp. 4513-4518. (doi: 10.1073/pnas.0807974105)

Ortolano, F. et al. (2009) Imaging T-cell movement in the brain during experimental cerebral malaria. Parasite Immunology, 31(3), 147-150 (4). (doi: 10.1111/j.1365-3024.2008.01090.x)

Maffia, P. , Zinselmeyer, B.H., Ialenti, A., Kennedy, S. , Baker, A.H., McInnes, I., Brewer, J.M. and Garside, P. (2007) Multiphoton microscopy for 3-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115(11), E326-E328. (doi: 10.1161/CIRCULATIONAHA.106.658492) (PMID:17372180)

Maffia, P. , Grassia, G., Di Meglio, P., Carnuccio, R., Berrino, L., Garside, P. , Ianaro, A. and Ialenti, A. (2006) Neutralization of interleukin-18 inhibits neointimal formation in a rat model of vascular injury. Circulation, 114, pp. 430-437. (doi: 10.1161/CIRCULATIONAHA.105.602714) (PMID:16864728)

Ialenti, A., Di Meglio, P., Grassia, G., Maffia, P. , Di Rosa, M., Lanzetta, R., Molinaro, A., Silipo, A., Grant, W. and Ianaro, A. (2006) A novel lipid A fromHalomonas magadiensis inhibits enteric LPS-induced human monocyte activation. European Journal of Immunology, 36(2), pp. 354-360. (doi: 10.1002/eji.200535305) (PMID:16365914)

Morello, S., Vellecco, V., Roviezzo, F., Maffia, P. , Cuzzocrea, S., Cirino, G. and Cicala, C. (2005) A protective role for proteinase activated receptor 2 in airways of lipopolysaccharide-treated rats. Biochemical Pharmacology, 71(1-2), pp. 223-230. (doi: 10.1016/j.bcp.2005.10.016) (PMID:16300746)

Corea, G., Fattorusso, E., Lanzotti, V., Di Meglio, P., Maffia, P. , Grassia, G., Ialenti, A. and Ianaro, A. (2005) Discovery and biological evaluation of the novel naturally occurring diterpene pepluanone as antiinflammatory agent. Journal of Medicinal Chemistry, 48(22), pp. 7055-7062. (doi: 10.1021/jm050321r) (PMID:16250665)

Ialenti, A., Grassia, G., Di Meglio, P., Maffia, P. , Di Rosa, M. and Ianaro, A. (2005) Mechanism of the anti-inflammatory effect of thiazolidinediones: relationship with the glucocorticoid pathway. Molecular Pharmacology, 67(5), pp. 1620-1628. (doi: 10.1124/mol.104.004895) (PMID:15684043)

Ialenti, A., Di Meglio, P., D'Acquisto, F., Pisano, B., Maffia, P. , Grassia, G., Di Rosa, M. and Ianaro, A. (2005) Inhibition of cyclooxygenase-2 gene expression by the heat shock response in J774 murine macrophages. European Journal of Pharmacology, 509(2-3), pp. 89-96. (doi: 10.1016/j.ejphar.2004.10.052) (PMID:15733543)

Maffia, P. , Brewer, J. M. , Gracie, J. A., Ianaro, A., Leung, B. P., Mitchell, P. J., Smith, K. M., McInnes, I. B. and Garside, P. (2004) Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173(1), pp. 151-156. (doi: 10.4049/jimmunol.173.1.151) (PMID:15210769)

Cuzzocrea, S. et al. (2004) Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-γ, reduces acute inflammation. European Journal of Pharmacology, 483(1), pp. 79-93. (doi: 10.1016/j.ejphar.2003.10.056) (PMID:14709329)

Lippolis, L., Sorrentino, R., Popolo, A., Maffia, P. , Nasti, C., Villa Bianca, R. d.’E. d., Marzocco, S., Autore, G. and Pinto, A. (2003) Time course of vascular reactivity to contracting and relaxing agents after endothelial denudation by balloon angioplasty in rat carotid artery. Atherosclerosis, 171(2), pp. 171-179. (doi: 10.1016/j.atherosclerosis.2003.07.012) (PMID:14644385)

Ianaro, A., Maffia, P. , Cuzzocrea, S., Mazzon, E., Santoro, M. G., Di Rosa, M. and Ialenti, A. (2003) 2-Cyclopenten-1-one and prostaglandin J2 reduce restenosis after balloon angioplasty in rats: role of NF-κB. FEBS Letters, 553(1-2), pp. 21-27. (doi: 10.1016/S0014-5793(03)00873-1) (PMID:14550540)

Ianaro, A., Ialenti, A., Maffia, P. , Di Meglio, P., Di Rosa, M. and Santoro, M. G. (2003) Anti-inflammatory activity of 15-deoxy- 12,14-PGJ2 and 2-cyclopenten-1-one: role of the heat shock response. Molecular Pharmacology, 64(1), pp. 85-93. (doi: 10.1124/mol.64.1.85) (PMID:12815164)

Ianaro, A., Maffia, P. , Rosa, M. and Ialenti, A. (2003) Cyclopentenone prostaglandins as anti-inflammatory agents: A novel therapeutic strategy? Current Medicinal Chemistry: Anti-Inflammatory and Anti-Allergy Agents, 2(2), pp. 85-93. (doi: 10.2174/1568014033483851)

Mascolo, N., Izzo, A. A., Ligresti, A., Costagliola, A., Pinto, L., Cascio, M. G., Maffia, P. , Cecio, A., Capasso, F. and Di Marzo, V. (2002) The endocannabinoid system and the molecular basis of paralytic ileus in mice. FASEB Journal, (doi: 10.1096/fj.02-0338fje) (PMID:12397089)

Borrelli, F., Izzo, A.A., Di Carlo, G., Maffia, P. , Russo, A., Maiello, F.M., Capasso, F. and Mascolo, N. (2002) Effect of a propolis extract and caffeic acid phenethyl ester on formation of aberrant crypt foci and tumors in the rat colon. Fitoterapia, 73(Supl 1), S38-S43. (doi: 10.1016/S0367-326X(02)00189-2) (PMID:12495708)

Borrelli, F., Maffia, P. , Pinto, L., Ianaro, A., Russo, A., Capasso, F. and Ialenti, A. (2002) Phytochemical compounds involved in the anti-inflammatory effect of propolis extract. Fitoterapia, 73(Supl 1), S53-S63. (doi: 10.1016/S0367-326X(02)00191-0) (PMID:12495710)

Maffia, P. , Ianaro, A., Sorrentino, R., Lippolis, L., Maiello, F. M., del Soldato, P., Ialenti, A. and Cirino, G. (2002) Beneficial effects of NO-releasing derivative of flurbiprofen (HCT-1026) in rat model of vascular injury and restenosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 22(2), pp. 263-267. (PMID:11834526)

Ianaro, A., Ialenti, A., Maffia, P. , Pisano, B. and Di Rosa, M. (2001) Role of cyclopentenone prostaglandins in rat carrageenin pleurisy. FEBS Letters, 508(1), pp. 61-66. (doi: 10.1016/S0014-5793(01)03035-6) (PMID:11707269)

D'Acquisto, F., Ianaro, A., Ialenti, A., Maffia, P. , Maiuri, M. and Carnuccio, R. (2001) Transcription factor decoy oligodeoxynucleotides to nuclear factor-κB inhibit reverse passive Arthus reaction in rat. Naunyn-Schmiedeberg's Archives of Pharmacology, 364(5), pp. 422-429. (doi: 10.1007/s002100100472) (PMID:11692225)

Ianaro, A., Ialenti, A., Maffia, P. , Pisano, B. and Di Rosa, M. (2001) HSF1/hsp72 pathway as an endogenous anti-inflammatory system. FEBS Letters, 499(3), pp. 239-244. (doi: 10.1016/S0014-5793(01)02569-8) (PMID:11423124)

Ialenti, A. et al. (2001) Synthesis of novel anti-inflammatory peptides derived from the amino-acid sequence of the bioactive protein SV-IV. European Journal of Biochemistry, 268(12), pp. 3399-3406. (doi: 10.1046/j.1432-1327.2001.02236.x) (PMID:11422369)

Ialenti, A., Ianaro, A., Maffia, P. , Sautebin, L. and Di Rosa, M. (2000) Nitric oxide inhibits leucocyte migration in carrageenin-induced rat pleurisy. Inflammation Research, 49(8), pp. 411-417. (doi: 10.1007/s000110050609) (PMID:11028758)

Ianaro, A., Ialenti, A., Maffia, P. , Sautebin, L., Rombolà, L., Carnuccio, R., Iuvone, T., D'Acquisto, F. and Di Rosa, M. (2000) Anti-inflammatory activity of macrolide antibiotics. Journal of Pharmacology and Experimental Therapeutics, 292(1), pp. 156-163. (PMID:10604943)

Costantino, V., Fattorusso, E., Mangoni, A., Rosa, M. D., Ianaro, A. and Maffia, P. (1996) Glycolipids from sponges. IV. Immunomodulating glycosyl ceramides from the marine sponge agelas dispar. Tetrahedron, 52(5), pp. 1573-1578. (doi: 10.1016/0040-4020(95)00986-8)

Caliendo, G., Greco, G., Grieco, P., Perissutti, E., Santagada, V., Ialenti, A., Maffia, P. , Albrizio, S. and Santini, A. (1996) Synthesis and antinociceptive activity of peptides related to interleukin-1β193–195 Lys-Pro-Thr. Biopolymers, 40(5), pp. 479-484. (doi: 10.1002/(SICI)1097-0282(1996)40:5<479::AID-BIP5>3.0.CO;2-T) (PMID:9062070)

Book Sections

McShane, L. , Sage, A. P. and Maffia, P. (2019) Inflammation and immunity in vascular diseases. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 229-238. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_21)

Grassia, G., MacRitchie, N. and Maffia, P. (2018) Immune mechanisms in atherosclerosis and potential for immunomodulatory therapies. In: Riccardi, C., Levi-Schaffer, F. and Tiligada, E. (eds.) Immunopharmacology and Inflammation. Springer: Cham, pp. 211-224. ISBN 9783319776576 (doi: 10.1007/978-3-319-77658-3_9)

Millington, O. R., Brewer, J. M. , Garside, P. and Maffia, P. (2010) Imaging interactions between the immune and cardiovascular systems in vivo by multiphoton microscopy. In: Marelli-Berg, F. M. and Nourshargh, S. (eds.) T-Cell Trafficking: Methods and Protocols. Series: Methods in Molecular Biology, 616 (616). Humana Press Inc, pp. 193-206. ISBN 9781607614609 (doi: 10.1007/978-1-60761-461-6_13)

This list was generated on Thu Nov 30 20:42:57 2023 GMT.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Cross disciplinary capacity building in ultra-high frequency preclinical cardiovascular ultrasound
    British Heart Foundation
    2022 - 2025
     
  • Defining EPAC1 as a therapeutic target for vascular inflammation and atherosclerosis
    British Heart Foundation
    2021 - 2024
     
  • Defining the IL-21/IL-21 receptor axis role(s) in atherosclerosis
    British Heart Foundation
    2021 - 2023
     
  • Defining AXL Role in Atherosclerosis
    British Heart Foundation
    2021 - 2023
     
  • Defining the individual and integrated roles of inflammatory chemokine receptors (iCCRs) in atherosclerosis
    British Heart Foundation
    2020 - 2023
     
  • Single cell sequencing of aortic immune cells from Angiotensis II-induced hypertensive mice
    Wellcome Trust
    2019 - 2020
     
  • Assessment of immune-inflammatory biomarkers
    National Centre for the Replacement, Refinement and Reduction of Animals Research
    2018 - 2019
     
  • Microwave Therapy for Atherosclerotic Lesions
    Scottish Funding Council
    2017 - 2018
     
  • Selective targeting of NF-??B by Bcl-3 in the control of vascular injury
    Tenovus Scotland
    2016 - 2017
     
  • ISSF Catalyst@ The Glasgow FANTOM6 consortium investigation of the role of LncRNAs in specifying tissue macrophage phenotypes
    Wellcome Trust
    2015 - 2016
     
  • NanoMATe
    European Commission
    2015 - 2017
     
  • In Situ Nanoparticle Assemblies for Healthcare Diagnostics and Therapy. Reference: 130479
    Engineering and Physical Sciences Research Council
    2014 - 2018
     
  • BHF centre of excellence
    British Heart Foundation
    2014 - 2019
     
  • Defining innate and adaptive immune functions of plasmacytoid dendritic cells in atherosclerosis.
    British Heart Foundation
    2013 - 2017
     
  • Imaging immune cells in lung in order to understand asthma
    Asthma UK
    2012 - 2012
     
  • Transfer of expertise in bioimaging from academia to industry.
    Scottish Funding Council
    2011 - 2012
     
  • Targeting cell contact to reduce autoimmunity and enhance vaccination
    Scottish Universities Life Sciences Alliance
    2011 - 2012
     
  • In Vivo Reporting using Nanosystems Chemistry and Optical Spectroscopy
    Engineering and Physical Sciences Research Council
    2010 - 2011
     
  • Visualising antigen presentation in mouse models of atherosclerosis
    Medical Research Scotland
    2010 - 2012
     
  • Investigating the role of T cells in vascular pathology
    British Heart Foundation
    2010 - 2010
     
  • Importance of mast cells in vein graft survival
    British Heart Foundation
    2010 - 2012
     

Supervision

Teaching

Since 2014, I have been Programme and/or Course Coordinator of the Senior Honours Immunology degree. The BSc (Hons) degree programme in Immunology has been running for over forty years. It was the first BSc Honours course in Immunology in Britain and continues to provide one of the most comprehensive undergraduate education in immunology in the country.

In addition to contributing to teaching for 2Y and 3Y Immunology, 1Y Medicine, 3Y Pharmacology, BMedSci in Inflammation Medicine, MVLS Research Training courses and MSc Infection Biology and Immunology, I am also a Fellow of the Higher Education Academy actively involved in the organization and delivery of self-funded national and international teaching and learning events such as the Spring School in Transferable Skills for students of the University of Naples Federico II (Italy) and the Integrated Mammalian Biology in vivo Immunology summer school.

I have been the External Examiner of the intercalated BMedSci degree course in Molecular Therapeutics at Barts & the London School of Medicine & Dentistry, and the recipient of the MVLS College Teaching Excellence Award.