Mr Moeed Akbar
- Research Fellow (Immunology & Infection)
email:
Moeed.Akbar@glasgow.ac.uk
Level 4, Iii - Gbrc, University Place, Glasgow G12 8TA
Publications
2023
Jaffery, H. et al. (2023) IĸB Protein BCL3 as a controller of osteogenesis and bone health. Arthritis and Rheumatology, 75(12), 2148-2160-2148-2160. (doi: 10.1002/art.42639) (PMID:37410754)
Orchard, Kayleigh J.A., Akbar, Moeed, Crower, Lindsay A.N., Cole, John, Millar, Neal L. ORCID: https://orcid.org/0000-0001-9251-9907 and Raleigh, Stuart M.
(2023)
Characterization of histone modifications in late-stage rotator cuff tendinopathy.
Genes, 14(2),
496.
(doi: 10.3390/genes14020496)
(PMID:36833423)
(PMCID:PMC9956879)
2022
Thümmler, Katja ORCID: https://orcid.org/0000-0002-1681-2359, Williams, Mark T.S., Kitson, Susan
ORCID: https://orcid.org/0009-0002-5112-1059, Sood, Shatakshi, Akbar, Moeed, Cole, John J., Goodyear, Carl S.
ORCID: https://orcid.org/0000-0001-5926-5941, Hunter, Ewan and Soutar, Richard
(2022)
Targeting 3D chromosomal architecture at the RANK loci to suppress myeloma-driven osteoclastogenesis.
OncoImmunology, 11(1),
2104070.
(doi: 10.1080/2162402X.2022.2104070)
(PMID:35936985)
(PMCID:PMC9348127)
Millar, N. L. et al. (2022) Frozen shoulder. Nature Reviews Disease Primers, 8, 59. (doi: 10.1038/s41572-022-00386-2) (PMID:36075904)
2021
Shi, Z. et al. (2021) Targeting the CCR6/CCL20 axis in entheseal and cutaneous inflammation. Arthritis and Rheumatology, 73(12), pp. 2271-2281. (doi: 10.1002/art.41882) (PMID:34081845)
Akbar, Moeed, MacDonald, Lucy ORCID: https://orcid.org/0000-0001-7727-3873, Crowe, Lindsay A.N., Carlberg, Konstantin, Kurowska-Stolarska, Mariola
ORCID: https://orcid.org/0000-0003-2124-7777, Ståhl, Patrik L., Snelling, Sarah J.B., McInnes, Iain B.
ORCID: https://orcid.org/0000-0002-6462-4280 and Millar, Neal L.
ORCID: https://orcid.org/0000-0001-9251-9907
(2021)
Single cell and spatial transcriptomics in human tendon disease indicate dysregulated immune homeostasis.
Annals of the Rheumatic Diseases, 80(11),
pp. 1494-1497.
(doi: 10.1136/annrheumdis-2021-220256)
(PMID:34001518)
(PMCID:PMC8522454)
Akbar, M. et al. (2021) Translational targeting of inflammation and fibrosis in frozen shoulder: Molecular dissection of the T cell/IL-17A axis. Proceedings of the National Academy of Sciences of the United States of America, 118(39), e210271511. (doi: 10.1073/pnas.2102715118) (PMID:34544860) (PMCID:PMC8488623)
Garcia-Melchor, Emma, Cafaro, Giacomo, MacDonald, Lucy ORCID: https://orcid.org/0000-0001-7727-3873, Crowe, Lindsay A.N., Sood, Shatakshi, McLean, Michael, Fazzi, Umberto, McInnes, Iain B.
ORCID: https://orcid.org/0000-0002-6462-4280, Akbar, Moeed and Millar, Neal L.
ORCID: https://orcid.org/0000-0001-9251-9907
(2021)
Novel self-amplificatory loop between T cells and tenocytes as a driver of chronicity in tendon disease.
Annals of the Rheumatic Diseases, 80(8),
pp. 1075-1085.
(doi: 10.1136/annrheumdis-2020-219335)
(PMID:33692018)
Crowe, Lindsay A.N., Melchor, Emma Garcia, Murrell, George A.C., McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280, Akbar, Moeed and Millar, Neal
ORCID: https://orcid.org/0000-0001-9251-9907
(2021)
Stromal ‘activation’ markers do not confer pathogenic activity in tendinopathy.
Translational Sports Medicine, 4(2),
pp. 268-279.
(doi: 10.1002/tsm2.204)
Atherton, C. M. et al. (2021) Vancomycin wrap for anterior cruciate ligament surgery. American Journal of Sports Medicine, 49(2), pp. 426-434. (doi: 10.1177/0363546520981570) (PMID:33406371) (PMCID:PMC7859666)
2020
Akbar, Moeed, Garcia-Melchor, Emma, Chilaka, Sabarinadh, Little, Kevin J., Sood, Shatakshi, Reilly, James H., Liew, Foo Y., McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Millar, Neal L.
ORCID: https://orcid.org/0000-0001-9251-9907
(2020)
Attenuation of Dupuytren’s fibrosis via targeting of the STAT-1 modulated IL-13RA1 response.
Science Advances, 6(28),
eaaz8272.
(doi: 10.1126/sciadv.aaz8272)
(PMID:32695877)
(PMCID:PMC7351483)
2019
Akbar, M. et al. (2019) Fibroblast activation and inflammation in frozen shoulder. PLoS ONE, 14(4), e0215301. (doi: 10.1371/journal.pone.0215301) (PMID:31013287) (PMCID:PMC6478286)
Abraham, A. C. et al. (2019) Targeting the NF-κB signaling pathway in chronic tendon disease. Science Translational Medicine, 11(481), eaav4319. (doi: 10.1126/scitranslmed.aav4319) (PMID:30814338) (PMCID:PMC6534967)
Crowe, L. A.N. et al. (2019) S100A8 & S100A9: alarmin mediated inflammation in tendinopathy. Scientific Reports, 9, 1463. (doi: 10.1038/s41598-018-37684-3) (PMID:30728384) (PMCID:PMC6365574)
McLean, M. et al. (2019) Tranexamic acid toxicity in human periarticular tissues. Bone and Joint Research, 8(1), pp. 11-18. (doi: 10.1302/2046-3758.81.BJR-2018-0181.R1) (PMID:30800295) (PMCID:PMC6359888)
2018
Cher, J. Z.B. et al. (2018) Alarmins in frozen shoulder: a molecular association between inflammation and pain. American Journal of Sports Medicine, 46(3), pp. 671-678. (doi: 10.1177/0363546517741127) (PMID:29190116)
2017
Watts, A. E. et al. (2017) MicroRNA29a treatment improves early tendon injury. Molecular Therapy, 25(10), pp. 2415-2426. (doi: 10.1016/j.ymthe.2017.07.015) (PMID:28822690)
Akbar, M. et al. (2017) Targeting danger molecules in tendinopathy: the HMGB1/TLR4 axis. RMD Open, 3(2), e000456. (doi: 10.1136/rmdopen-2017-000456) (PMID:28879051) (PMCID:PMC5574425)
2016
Millar, N. L. et al. (2016) IL-17A mediates inflammatory and tissue remodelling events in early human tendinopathy. Scientific Reports, 6, 27149. (doi: 10.1038/srep27149) (PMID:27263531) (PMCID:PMC4893609)
2015
Millar, Neal L. ORCID: https://orcid.org/0000-0001-9251-9907, Gilchrist, Derek, Akbar, Moeed, Reilly, James H., Kerr, Shauna C., Campbell, Abigail L., Murrell, George A.C., Liew, Foo Y., Kurowska-Stolarska, Mariola
ORCID: https://orcid.org/0000-0003-2124-7777 and McInnes, Iain B.
ORCID: https://orcid.org/0000-0002-6462-4280
(2015)
MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease.
Nature Communications, 6,
6774.
(doi: 10.1038/ncomms7774)
(PMID:25857925)
(PMCID:PMC4403384)
2014
Colombo, M. et al. (2014) Notch signaling drives multiple myeloma induced osteoclastogenesis. Oncotarget, 5(21), pp. 10393-10406. (doi: 10.18632/oncotarget.2084) (PMID:25257302) (PMCID:PMC4279381)
2012
Akbar, Moeed, Fraser, Alasdair R., Graham, Gerard J. ORCID: https://orcid.org/0000-0002-7801-204X, Brewer, James M.
ORCID: https://orcid.org/0000-0001-7933-0915 and Grant, M. Helen
(2012)
Acute inflammatory response to cobalt chromium orthopaedic wear debris in a rodent air-pouch model.
Journal of the Royal Society: Interface, 9(74),
pp. 2109-2119.
(doi: 10.1098/rsif.2012.0006)
Afolaranmi, G.A., Akbar, M., Brewer, J. ORCID: https://orcid.org/0000-0001-7933-0915 and Grant, M.H.
(2012)
Distribution of metal released from cobalt-chromium alloy orthopaedic wear particles implanted into air pouches in mice.
Journal of Biomedical Materials Research Part A, 100A(6),
pp. 1529-1538.
(doi: 10.1002/jbm.a.34091)
2011
Akbar, Moeed, Brewer, J.M. ORCID: https://orcid.org/0000-0001-7933-0915 and Grant, M.H.
(2011)
Effect of chromium and cobalt ions on primary human lymphocytesin vitro.
Journal of Immunotoxicology, 8(2),
pp. 140-149.
(doi: 10.3109/1547691X.2011.553845)
Articles
Jaffery, H. et al. (2023) IĸB Protein BCL3 as a controller of osteogenesis and bone health. Arthritis and Rheumatology, 75(12), 2148-2160-2148-2160. (doi: 10.1002/art.42639) (PMID:37410754)
Orchard, Kayleigh J.A., Akbar, Moeed, Crower, Lindsay A.N., Cole, John, Millar, Neal L. ORCID: https://orcid.org/0000-0001-9251-9907 and Raleigh, Stuart M.
(2023)
Characterization of histone modifications in late-stage rotator cuff tendinopathy.
Genes, 14(2),
496.
(doi: 10.3390/genes14020496)
(PMID:36833423)
(PMCID:PMC9956879)
Thümmler, Katja ORCID: https://orcid.org/0000-0002-1681-2359, Williams, Mark T.S., Kitson, Susan
ORCID: https://orcid.org/0009-0002-5112-1059, Sood, Shatakshi, Akbar, Moeed, Cole, John J., Goodyear, Carl S.
ORCID: https://orcid.org/0000-0001-5926-5941, Hunter, Ewan and Soutar, Richard
(2022)
Targeting 3D chromosomal architecture at the RANK loci to suppress myeloma-driven osteoclastogenesis.
OncoImmunology, 11(1),
2104070.
(doi: 10.1080/2162402X.2022.2104070)
(PMID:35936985)
(PMCID:PMC9348127)
Millar, N. L. et al. (2022) Frozen shoulder. Nature Reviews Disease Primers, 8, 59. (doi: 10.1038/s41572-022-00386-2) (PMID:36075904)
Shi, Z. et al. (2021) Targeting the CCR6/CCL20 axis in entheseal and cutaneous inflammation. Arthritis and Rheumatology, 73(12), pp. 2271-2281. (doi: 10.1002/art.41882) (PMID:34081845)
Akbar, Moeed, MacDonald, Lucy ORCID: https://orcid.org/0000-0001-7727-3873, Crowe, Lindsay A.N., Carlberg, Konstantin, Kurowska-Stolarska, Mariola
ORCID: https://orcid.org/0000-0003-2124-7777, Ståhl, Patrik L., Snelling, Sarah J.B., McInnes, Iain B.
ORCID: https://orcid.org/0000-0002-6462-4280 and Millar, Neal L.
ORCID: https://orcid.org/0000-0001-9251-9907
(2021)
Single cell and spatial transcriptomics in human tendon disease indicate dysregulated immune homeostasis.
Annals of the Rheumatic Diseases, 80(11),
pp. 1494-1497.
(doi: 10.1136/annrheumdis-2021-220256)
(PMID:34001518)
(PMCID:PMC8522454)
Akbar, M. et al. (2021) Translational targeting of inflammation and fibrosis in frozen shoulder: Molecular dissection of the T cell/IL-17A axis. Proceedings of the National Academy of Sciences of the United States of America, 118(39), e210271511. (doi: 10.1073/pnas.2102715118) (PMID:34544860) (PMCID:PMC8488623)
Garcia-Melchor, Emma, Cafaro, Giacomo, MacDonald, Lucy ORCID: https://orcid.org/0000-0001-7727-3873, Crowe, Lindsay A.N., Sood, Shatakshi, McLean, Michael, Fazzi, Umberto, McInnes, Iain B.
ORCID: https://orcid.org/0000-0002-6462-4280, Akbar, Moeed and Millar, Neal L.
ORCID: https://orcid.org/0000-0001-9251-9907
(2021)
Novel self-amplificatory loop between T cells and tenocytes as a driver of chronicity in tendon disease.
Annals of the Rheumatic Diseases, 80(8),
pp. 1075-1085.
(doi: 10.1136/annrheumdis-2020-219335)
(PMID:33692018)
Crowe, Lindsay A.N., Melchor, Emma Garcia, Murrell, George A.C., McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280, Akbar, Moeed and Millar, Neal
ORCID: https://orcid.org/0000-0001-9251-9907
(2021)
Stromal ‘activation’ markers do not confer pathogenic activity in tendinopathy.
Translational Sports Medicine, 4(2),
pp. 268-279.
(doi: 10.1002/tsm2.204)
Atherton, C. M. et al. (2021) Vancomycin wrap for anterior cruciate ligament surgery. American Journal of Sports Medicine, 49(2), pp. 426-434. (doi: 10.1177/0363546520981570) (PMID:33406371) (PMCID:PMC7859666)
Akbar, Moeed, Garcia-Melchor, Emma, Chilaka, Sabarinadh, Little, Kevin J., Sood, Shatakshi, Reilly, James H., Liew, Foo Y., McInnes, Iain B. ORCID: https://orcid.org/0000-0002-6462-4280 and Millar, Neal L.
ORCID: https://orcid.org/0000-0001-9251-9907
(2020)
Attenuation of Dupuytren’s fibrosis via targeting of the STAT-1 modulated IL-13RA1 response.
Science Advances, 6(28),
eaaz8272.
(doi: 10.1126/sciadv.aaz8272)
(PMID:32695877)
(PMCID:PMC7351483)
Akbar, M. et al. (2019) Fibroblast activation and inflammation in frozen shoulder. PLoS ONE, 14(4), e0215301. (doi: 10.1371/journal.pone.0215301) (PMID:31013287) (PMCID:PMC6478286)
Abraham, A. C. et al. (2019) Targeting the NF-κB signaling pathway in chronic tendon disease. Science Translational Medicine, 11(481), eaav4319. (doi: 10.1126/scitranslmed.aav4319) (PMID:30814338) (PMCID:PMC6534967)
Crowe, L. A.N. et al. (2019) S100A8 & S100A9: alarmin mediated inflammation in tendinopathy. Scientific Reports, 9, 1463. (doi: 10.1038/s41598-018-37684-3) (PMID:30728384) (PMCID:PMC6365574)
McLean, M. et al. (2019) Tranexamic acid toxicity in human periarticular tissues. Bone and Joint Research, 8(1), pp. 11-18. (doi: 10.1302/2046-3758.81.BJR-2018-0181.R1) (PMID:30800295) (PMCID:PMC6359888)
Cher, J. Z.B. et al. (2018) Alarmins in frozen shoulder: a molecular association between inflammation and pain. American Journal of Sports Medicine, 46(3), pp. 671-678. (doi: 10.1177/0363546517741127) (PMID:29190116)
Watts, A. E. et al. (2017) MicroRNA29a treatment improves early tendon injury. Molecular Therapy, 25(10), pp. 2415-2426. (doi: 10.1016/j.ymthe.2017.07.015) (PMID:28822690)
Akbar, M. et al. (2017) Targeting danger molecules in tendinopathy: the HMGB1/TLR4 axis. RMD Open, 3(2), e000456. (doi: 10.1136/rmdopen-2017-000456) (PMID:28879051) (PMCID:PMC5574425)
Millar, N. L. et al. (2016) IL-17A mediates inflammatory and tissue remodelling events in early human tendinopathy. Scientific Reports, 6, 27149. (doi: 10.1038/srep27149) (PMID:27263531) (PMCID:PMC4893609)
Millar, Neal L. ORCID: https://orcid.org/0000-0001-9251-9907, Gilchrist, Derek, Akbar, Moeed, Reilly, James H., Kerr, Shauna C., Campbell, Abigail L., Murrell, George A.C., Liew, Foo Y., Kurowska-Stolarska, Mariola
ORCID: https://orcid.org/0000-0003-2124-7777 and McInnes, Iain B.
ORCID: https://orcid.org/0000-0002-6462-4280
(2015)
MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease.
Nature Communications, 6,
6774.
(doi: 10.1038/ncomms7774)
(PMID:25857925)
(PMCID:PMC4403384)
Colombo, M. et al. (2014) Notch signaling drives multiple myeloma induced osteoclastogenesis. Oncotarget, 5(21), pp. 10393-10406. (doi: 10.18632/oncotarget.2084) (PMID:25257302) (PMCID:PMC4279381)
Akbar, Moeed, Fraser, Alasdair R., Graham, Gerard J. ORCID: https://orcid.org/0000-0002-7801-204X, Brewer, James M.
ORCID: https://orcid.org/0000-0001-7933-0915 and Grant, M. Helen
(2012)
Acute inflammatory response to cobalt chromium orthopaedic wear debris in a rodent air-pouch model.
Journal of the Royal Society: Interface, 9(74),
pp. 2109-2119.
(doi: 10.1098/rsif.2012.0006)
Afolaranmi, G.A., Akbar, M., Brewer, J. ORCID: https://orcid.org/0000-0001-7933-0915 and Grant, M.H.
(2012)
Distribution of metal released from cobalt-chromium alloy orthopaedic wear particles implanted into air pouches in mice.
Journal of Biomedical Materials Research Part A, 100A(6),
pp. 1529-1538.
(doi: 10.1002/jbm.a.34091)
Akbar, Moeed, Brewer, J.M. ORCID: https://orcid.org/0000-0001-7933-0915 and Grant, M.H.
(2011)
Effect of chromium and cobalt ions on primary human lymphocytesin vitro.
Journal of Immunotoxicology, 8(2),
pp. 140-149.
(doi: 10.3109/1547691X.2011.553845)
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Common translational mechanisms in fibrosis
Medical Research Council
2023 - 2024
Supervision
- Burgy, Clara Lucianna Dina
A study into the effect of unlevel footfall on lameness in horses