Dr Lorena Fernandez-Martinez

  • Reader in Bacteriology (Bacteriology)

telephone: 0141 330 6685
email: Lorena.Fernandez@glasgow.ac.uk

B223, Sir Graeme Davis Building, 120 University Place, Glasgow, G12 8TA

Import to contacts

ORCID iDhttps://orcid.org/0000-0002-5430-4056

Biography

I obtained my PhD from Swansea University where I worked on the regulation of stress responses in the bacterial genus Streptomyces under the supervision of Prof. Paul Dyson.

I then moved onto a post-doctoral position in INBIOTEC, a biotechnology institute in León, Spain, working on signal transduction, genome sequencing and proteome analysis in Streptomyces.

I then joined Prof. Mervyn Bibb’s research group as a post-doctoral scientist at the John Innes Centre, where I worked on the regulation of antibiotic production. I also developed genetic tools to work with actinomycetes and worked with Prof. Barrie Wilkinson studying virulence factors in the opportunistic pathogen Pseudomonas aeruginosa in order to use these as potential drug targets.

I then secured my first academic position at Edge Hill University where I continued working on regulation of antibiotic biosynthetic gene clusters and developed research in understanding soil microbial interactions, an area which I find fascinating.

I have now joined the School of Infection and Immunity at the University of Glasgow where I am a Reader in Bacteriology.

Research interests

My research interests include:

Study of interactions between Streptomyces species and other soil microorganisms in soil systems, with the aim to understand how these bacteria behave and communicate with other soil microbial community members as well as to identify the signals leading to the production of silent natural products with potential biotechnological applications.

Understanding the complex regulatory pathways that lead to antibiotic production in Actinobacteria as well as the study of the regulation of resistance mechanisms in antibiotic producing bacteria (the likely source of clinically relevant antibiotic resistance).

Activation of silent specialised metabolite gene clusters in Actinobacteria by using gene manipulation, co-cultivation and environmental extracellular signalling methods in order to characterise new gene clusters encoding novel compounds with antibiotic activity.

Publications

List by: Type | Date

Jump to: 2024
Number of items: 2.

2024

Schniete, J. K. and Fernández-Martínez, L. T. (2024) Natural product discovery in soil actinomycetes: unlocking their potential within an ecological context. Current Opinion in Microbiology, 79, 102487. (doi: 10.1016/j.mib.2024.102487) (PMID:38733791)

Fernández-Martínez, L. T. , Javelle, A. and Hoskisson, P. A. (2024) Microbial Primer: Bacterial growth kinetics. Microbiology, 170(2), 001428. (doi: 10.1099/mic.0.001428) (PMID:38329407) (PMCID:PMC10924458)

This list was generated on Sat Oct 12 16:12:39 2024 BST.
Jump to: Articles
Number of items: 2.

Articles

Schniete, J. K. and Fernández-Martínez, L. T. (2024) Natural product discovery in soil actinomycetes: unlocking their potential within an ecological context. Current Opinion in Microbiology, 79, 102487. (doi: 10.1016/j.mib.2024.102487) (PMID:38733791)

Fernández-Martínez, L. T. , Javelle, A. and Hoskisson, P. A. (2024) Microbial Primer: Bacterial growth kinetics. Microbiology, 170(2), 001428. (doi: 10.1099/mic.0.001428) (PMID:38329407) (PMCID:PMC10924458)

This list was generated on Sat Oct 12 16:12:39 2024 BST.