Dr Jennifer Ann Black
- Affiliate Researcher (School of Infection & Immunity)
email:
Jennifer.Stortz@glasgow.ac.uk
RI III, Sir Graeme Davies Building, 120 University Place, Glasgow, G12 8TA
Publications
2025
Black, J.A., Poulton, B.C. ORCID: https://orcid.org/0000-0002-9831-5697, Gonzaga, B., Iskantar, A., Paape, D.
ORCID: https://orcid.org/0000-0003-4355-8058, Tosi, L.R.O. and McCulloch, R.
ORCID: https://orcid.org/0000-0001-5739-976X
(2025)
AUK3 is required for faithful nuclear segregation in the bloodstream form of Trypanosoma brucei.
Molecular and Biochemical Parasitology, 261,
111664.
(doi: 10.1016/j.molbiopara.2024.111664)
(PMID:39746453)
2024
Reis-Cunha, João L., Pimenta-Carvalho, Samuel A., Almeida, Laila V., Coqueiro-Dos-Santos, Anderson, Marques, Catarina A. ORCID: https://orcid.org/0000-0003-1324-5448, Black, Jennifer A., Damasceno, Jeziel
ORCID: https://orcid.org/0000-0003-2077-3214, McCulloch, Richard
ORCID: https://orcid.org/0000-0001-5739-976X, Bartholomeu, Daniella C. and Jeffares, Daniel C.
(2024)
Ancestral aneuploidy and stable chromosomal duplication resulting in differential genome structure and gene expression control in trypanosomatid parasites.
Genome Research, 34(3),
pp. 441-453.
(doi: 10.1101/gr.278550.123)
(PMID:38604731)
(PMCID:PMC11067883)
2023
Black, Jennifer A., Klinger, Christen M., Lemgruber, Leandro ORCID: https://orcid.org/0000-0003-2832-6806, Dacks, Joel B., Mottram, Jeremy C. and McCulloch, Richard
ORCID: https://orcid.org/0000-0001-5739-976X
(2023)
AAK1-like: a putative pseudokinase with potential roles in cargo uptake in bloodstream form Trypanosoma brucei parasites.
Journal of Eukaryotic Microbiology, 70(6),
e12994.
(doi: 10.1111/jeu.12994)
(PMID:37548427)
Black, Jennifer A., Reis-Cunha, João Luís, Cruz, Angela. K. and Tosi, Luiz. R.O. (2023) Life in plastic, it’s fantastic! How Leishmania exploit genome instability to shape gene expression. Frontiers in Cellular and Infection Microbiology, 13, 1102462. (doi: 10.3389/fcimb.2023.1102462) (PMID:36779182) (PMCID:PMC9910336)
2022
Faria, Joana, Briggs, Emma M., Black, Jennifer A. and McCulloch, Richard ORCID: https://orcid.org/0000-0001-5739-976X
(2022)
Emergence and adaptation of the cellular machinery directing antigenic variation in the African trypanosome.
Current Opinion in Microbiology, 70,
102209.
(doi: 10.1016/j.mib.2022.102209)
(PMID:36215868)
2021
Silva, Gabriel L.A., Tosi, Luiz R.O., McCulloch, Richard ORCID: https://orcid.org/0000-0001-5739-976X and Black, Jennifer Ann
(2021)
Unpicking the roles of DNA damage protein kinases in trypanosomatids.
Frontiers in Cell and Developmental Biology, 9,
636615.
(doi: 10.3389/fcell.2021.636615)
(PMID:34422791)
(PMCID:PMC8377203)
Damasceno, Jeziel D. ORCID: https://orcid.org/0000-0003-2077-3214, Marques, Catarina A.
ORCID: https://orcid.org/0000-0003-1324-5448, Black, Jennifer, Briggs, Emma and McCulloch, Richard
ORCID: https://orcid.org/0000-0001-5739-976X
(2021)
Read, write, adapt: challenges and opportunities during kinetoplastid genome replication.
Trends in Genetics, 37(1),
pp. 21-34.
(doi: 10.1016/j.tig.2020.09.002)
(PMID:32993968)
(PMCID:PMC9213392)
2020
Briggs, Emma M., Marques, Catarina ORCID: https://orcid.org/0000-0003-1324-5448, Reis-Cunha, Joao, Black, Jennifer, Campbell, Samantha, Damasceno, Jeziel
ORCID: https://orcid.org/0000-0003-2077-3214, Bartholomeu, Daniella, Crouch, Kathryn
ORCID: https://orcid.org/0000-0001-9310-4762 and McCulloch, Richard
ORCID: https://orcid.org/0000-0001-5739-976X
(2020)
Next-generation analysis of trypanosomatid genome stability and instability.
In: Michels, Paul A.M., Ginger, Michael L. and Zilberstein, Dan (eds.)
Trypanosomatids: Methods and Protocols.
Series: Methods in Molecular Biology (2116).
Springer, pp. 225-262.
ISBN 9781071602935
(doi: 10.1007/978-1-0716-0294-2_15)
Black, Jennifer Ann, Crouch, Kathryn ORCID: https://orcid.org/0000-0001-9310-4762, Lemgruber, Leandro
ORCID: https://orcid.org/0000-0003-2832-6806, Lapsley, Craig, Dickens, Nicholas
ORCID: https://orcid.org/0000-0003-0492-5855, Tosi, Luiz R.O., Mottram, Jeremy C.
ORCID: https://orcid.org/0000-0001-5574-3766 and McCulloch, Richard
ORCID: https://orcid.org/0000-0001-5739-976X
(2020)
Trypanosoma brucei ATR links DNA damage signalling during antigenic variation with regulation of RNA Polymerase I-transcribed surface antigens.
Cell Reports, 30(3),
836-851.e5.
(doi: 10.1016/j.celrep.2019.12.049)
(PMID:31968257)
(PMCID:PMC6988115)
2019
Nnadi, Charles, Ebiloma, Godwin U., Black, Jennifer A., Nwodo, Ngozi, Lemgruber, Leandro ORCID: https://orcid.org/0000-0003-2832-6806, Schmidt, Thomas J. and De Koning, Harry P.
ORCID: https://orcid.org/0000-0002-9963-1827
(2019)
Potent antitrypanosomal activities of 3-aminosteroids against African trypanosomes: investigation of cellular effects and of cross-resistance with existing drugs.
Molecules, 24(2),
268.
(doi: 10.3390/molecules24020268)
(PMID:30642032)
2017
Stortz, J. A. et al. (2017) Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei. PLoS Pathogens, 13(7), e1006477. (doi: 10.1371/journal.ppat.1006477) (PMID:28742144) (PMCID:PMC5542689)
Articles
Black, J.A., Poulton, B.C. ORCID: https://orcid.org/0000-0002-9831-5697, Gonzaga, B., Iskantar, A., Paape, D.
ORCID: https://orcid.org/0000-0003-4355-8058, Tosi, L.R.O. and McCulloch, R.
ORCID: https://orcid.org/0000-0001-5739-976X
(2025)
AUK3 is required for faithful nuclear segregation in the bloodstream form of Trypanosoma brucei.
Molecular and Biochemical Parasitology, 261,
111664.
(doi: 10.1016/j.molbiopara.2024.111664)
(PMID:39746453)
Reis-Cunha, João L., Pimenta-Carvalho, Samuel A., Almeida, Laila V., Coqueiro-Dos-Santos, Anderson, Marques, Catarina A. ORCID: https://orcid.org/0000-0003-1324-5448, Black, Jennifer A., Damasceno, Jeziel
ORCID: https://orcid.org/0000-0003-2077-3214, McCulloch, Richard
ORCID: https://orcid.org/0000-0001-5739-976X, Bartholomeu, Daniella C. and Jeffares, Daniel C.
(2024)
Ancestral aneuploidy and stable chromosomal duplication resulting in differential genome structure and gene expression control in trypanosomatid parasites.
Genome Research, 34(3),
pp. 441-453.
(doi: 10.1101/gr.278550.123)
(PMID:38604731)
(PMCID:PMC11067883)
Black, Jennifer A., Klinger, Christen M., Lemgruber, Leandro ORCID: https://orcid.org/0000-0003-2832-6806, Dacks, Joel B., Mottram, Jeremy C. and McCulloch, Richard
ORCID: https://orcid.org/0000-0001-5739-976X
(2023)
AAK1-like: a putative pseudokinase with potential roles in cargo uptake in bloodstream form Trypanosoma brucei parasites.
Journal of Eukaryotic Microbiology, 70(6),
e12994.
(doi: 10.1111/jeu.12994)
(PMID:37548427)
Black, Jennifer A., Reis-Cunha, João Luís, Cruz, Angela. K. and Tosi, Luiz. R.O. (2023) Life in plastic, it’s fantastic! How Leishmania exploit genome instability to shape gene expression. Frontiers in Cellular and Infection Microbiology, 13, 1102462. (doi: 10.3389/fcimb.2023.1102462) (PMID:36779182) (PMCID:PMC9910336)
Faria, Joana, Briggs, Emma M., Black, Jennifer A. and McCulloch, Richard ORCID: https://orcid.org/0000-0001-5739-976X
(2022)
Emergence and adaptation of the cellular machinery directing antigenic variation in the African trypanosome.
Current Opinion in Microbiology, 70,
102209.
(doi: 10.1016/j.mib.2022.102209)
(PMID:36215868)
Silva, Gabriel L.A., Tosi, Luiz R.O., McCulloch, Richard ORCID: https://orcid.org/0000-0001-5739-976X and Black, Jennifer Ann
(2021)
Unpicking the roles of DNA damage protein kinases in trypanosomatids.
Frontiers in Cell and Developmental Biology, 9,
636615.
(doi: 10.3389/fcell.2021.636615)
(PMID:34422791)
(PMCID:PMC8377203)
Damasceno, Jeziel D. ORCID: https://orcid.org/0000-0003-2077-3214, Marques, Catarina A.
ORCID: https://orcid.org/0000-0003-1324-5448, Black, Jennifer, Briggs, Emma and McCulloch, Richard
ORCID: https://orcid.org/0000-0001-5739-976X
(2021)
Read, write, adapt: challenges and opportunities during kinetoplastid genome replication.
Trends in Genetics, 37(1),
pp. 21-34.
(doi: 10.1016/j.tig.2020.09.002)
(PMID:32993968)
(PMCID:PMC9213392)
Black, Jennifer Ann, Crouch, Kathryn ORCID: https://orcid.org/0000-0001-9310-4762, Lemgruber, Leandro
ORCID: https://orcid.org/0000-0003-2832-6806, Lapsley, Craig, Dickens, Nicholas
ORCID: https://orcid.org/0000-0003-0492-5855, Tosi, Luiz R.O., Mottram, Jeremy C.
ORCID: https://orcid.org/0000-0001-5574-3766 and McCulloch, Richard
ORCID: https://orcid.org/0000-0001-5739-976X
(2020)
Trypanosoma brucei ATR links DNA damage signalling during antigenic variation with regulation of RNA Polymerase I-transcribed surface antigens.
Cell Reports, 30(3),
836-851.e5.
(doi: 10.1016/j.celrep.2019.12.049)
(PMID:31968257)
(PMCID:PMC6988115)
Nnadi, Charles, Ebiloma, Godwin U., Black, Jennifer A., Nwodo, Ngozi, Lemgruber, Leandro ORCID: https://orcid.org/0000-0003-2832-6806, Schmidt, Thomas J. and De Koning, Harry P.
ORCID: https://orcid.org/0000-0002-9963-1827
(2019)
Potent antitrypanosomal activities of 3-aminosteroids against African trypanosomes: investigation of cellular effects and of cross-resistance with existing drugs.
Molecules, 24(2),
268.
(doi: 10.3390/molecules24020268)
(PMID:30642032)
Stortz, J. A. et al. (2017) Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei. PLoS Pathogens, 13(7), e1006477. (doi: 10.1371/journal.ppat.1006477) (PMID:28742144) (PMCID:PMC5542689)
Book Sections
Briggs, Emma M., Marques, Catarina ORCID: https://orcid.org/0000-0003-1324-5448, Reis-Cunha, Joao, Black, Jennifer, Campbell, Samantha, Damasceno, Jeziel
ORCID: https://orcid.org/0000-0003-2077-3214, Bartholomeu, Daniella, Crouch, Kathryn
ORCID: https://orcid.org/0000-0001-9310-4762 and McCulloch, Richard
ORCID: https://orcid.org/0000-0001-5739-976X
(2020)
Next-generation analysis of trypanosomatid genome stability and instability.
In: Michels, Paul A.M., Ginger, Michael L. and Zilberstein, Dan (eds.)
Trypanosomatids: Methods and Protocols.
Series: Methods in Molecular Biology (2116).
Springer, pp. 225-262.
ISBN 9781071602935
(doi: 10.1007/978-1-0716-0294-2_15)