Professor Allan Mowat
- Honorary Senior Research Fellow (School of Infection & Immunity)
email:
Allan.Mowat@glasgow.ac.uk
B419 Level B4, Immunology Section, Gbrc, Glasgow G12 8TA
Publications
2023
Pærregaard, S. I. et al. (2023) The small and large intestine contain related mesenchymal subsets that derive from embryonic Gli1+ precursors. Nature Communications, 14, 2307. (doi: 10.1038/s41467-023-37952-5) (PMID:37085516) (PMCID:PMC10121680)
2022
Luda, K. M., Da Silva, C., Ahmadi, F., Mowat, A. M., Ohno, H., Kotarsky, K. and Agace, W. W. (2022) Identification and characterization of murine glycoprotein 2‐expressing intestinal dendritic cells. Scandinavian Journal of Immunology, 96(5), e13219. (doi: 10.1111/sji.13219)
2021
Johnson, S. A. et al. (2021) Monocytes mediate Salmonella Typhimurium-induced tumor growth inhibition in a mouse melanoma model. European Journal of Immunology, 51(12), pp. 3228-3238. (doi: 10.1002/eji.202048913) (PMID:34633664) (PMCID:PMC9214623)
Wright, P. B. et al. (2021) The mannose receptor (CD206) identifies a population of colonic macrophages in health and inflammatory bowel disease. Scientific Reports, 11, 19616. (doi: 10.1038/s41598-021-98611-7) (PMID:34608184) (PMCID:PMC8490356)
Mowat, A. M. and Bain, C. C. (2021) Guardians of the epithelium: macrophages protect against toxic fungal derivatives. Mucosal Immunology, 14(3), pp. 542-543. (doi: 10.1038/s41385-020-00369-0) (PMID:33495494) (PMCID:PMC8076022)
Mowat, A. M. (2021) Historical perspective: Metchnikoff and the intestinal microbiome. Journal of Leukocyte Biology, 109(3), pp. 513-517. (doi: 10.1002/JLB.4RI0920-599) (PMID:33630385)
2018
Scott, N. A. et al. (2018) Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis. Science Translational Medicine, 10(464), eaao4755. (doi: 10.1126/scitranslmed.aao4755) (PMID:30355800) (PMCID:PMC6548564)
Thomson, C. A., van de Pavert, S. A., Stakenborg, M., Labeeuw, E., Matteoli, G., Mowat, A. M. and Nibbs, R. J.B. (2018) Expression of the atypical chemokine receptor ACKR4 identifies a novel population of intestinal submucosal fibroblasts that preferentially expresses endothelial cell regulators. Journal of Immunology, 201(1), pp. 215-229. (doi: 10.4049/jimmunol.1700967) (PMID:29760193) (PMCID:PMC6013047)
Kumawat, A. K., Yu, C., Mann, E. A., Schridde, A., Finnemann, S. C. and Mowat, A. M. (2018) Expression and characterisation of αvβ5 integrin on intestinal macrophages. European Journal of Immunology, 48(7), pp. 1181-1187. (doi: 10.1002/eji.201747318) (PMID:29676784) (PMCID:PMC6207937)
Bain, C. C., Oliphant, C. J., Thomson, C. A., Kullberg, M. C. and Mowat, A. M. (2018) Pro-inflammatory role of monocyte-derived CX3CR1int macrophages in Helicobacter hepaticus-induced colitis. Infection and Immunity, 86(2), e00579-17. (doi: 10.1128/IAI.00579-17) (PMID:29203542) (PMCID:PMC5778360)
Mowat, A. M. (2018) To respond or not to respond - a personal perspective of intestinal tolerance. Nature Reviews Immunology, 18, pp. 405-415. (doi: 10.1038/s41577-018-0002-x) (PMID:29491358)
2017
Mowat, A. M. (2017) Janus-like monocytes regulate postoperative ileus. Gut, 66(12), pp. 2049-2050. (doi: 10.1136/gutjnl-2017-314360) (PMID:28615300)
Mowat, A. M., Scott, C. L. and Bain, C. C. (2017) Barrier-tissue macrophages: functional adaptation to environmental challenges. Nature Medicine, 23(11), pp. 1258-1270. (doi: 10.1038/nm.4430) (PMID:29117177)
Bain, C.C. et al. (2017) TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine. Nature Communications, 8, 620. (doi: 10.1038/s41467-017-00658-6) (PMID:28931816) (PMCID:PMC5607002)
Joeris, T., Müller-Luda, K., Agace, W.W. and Mowat, A. M. (2017) Diversity and functions of intestinal mononuclear phagocytes. Mucosal Immunology, 10(4), pp. 845-864. (doi: 10.1038/mi.2017.22) (PMID:28378807)
Mowat, A. M. and Bain, C. C. (2017) Alternative monocytes settle in for the long term. Nature Immunology, 18(6), pp. 599-600. (doi: 10.1038/ni.3749) (PMID:28518159)
Scott, C. L., Bain, C. C. and Mowat, A. M. (2017) Isolation and identification of intestinal myeloid cells. In: Clausen, B. E. and Laman, J. D. (eds.) Inflammation: Methods and Protocols. Series: Methods in molecular biology (1559). Humana Press, pp. 223-239. ISBN 9781493967841 (doi: 10.1007/978-1-4939-6786-5_15)
Schridde, A. et al. (2017) Tissue-specific differentiation of colonic macrophages requires TGFβ receptor-mediated signaling. Mucosal Immunology, 10, pp. 1387-1399. (doi: 10.1038/mi.2016.142) (PMID:28145440) (PMCID:PMC5417360)
2016
Araya, R. E., Gomez Castro, M. F., Carasi, P., McCarville, J. L., Jury, J., Mowat, A. M., Verdu, E. F. and Chirdo, F. G. (2016) Mechanisms of innate immune activation by gluten peptide p31-43 in mice. American Journal of Physiology: Gastrointestinal and Liver Physiology, 311(1), G40-G49. (doi: 10.1152/ajpgi.00435.2015) (PMID:27151946)
Veenbergen, S. et al. (2016) Colonic tolerance develops in the iliac lymph nodes and can be established independent of CD103+ dendritic cells. Mucosal Immunology, 9(4), pp. 894-906. (doi: 10.1038/mi.2015.118) (PMID:26577569) (PMCID:PMC4871788)
Bain, C. C. et al. (2016) Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities. Nature Communications, 7, ncomms1185. (doi: 10.1038/ncomms11852) (PMID:27292029) (PMCID:PMC4910019)
Houston, S.A., Cerovic, V., Thomson, C., Brewer, J. , Mowat, A.M. and Milling, S. (2016) The lymph nodes draining the small intestine and colon are anatomically separate and immunologically distinct. Mucosal Immunology, 9(2), pp. 468-478. (doi: 10.1038/mi.2015.77) (PMID:26329428)
Scott, C. L., Wright, P. B., Milling, S. W.F. and Mowat, A. M. (2016) Isolation and identification of conventional dendritic cell subsets from the intestine of mice and men. In: Segura, E. and Onai, N. (eds.) Dendritic Cell Protocols. Series: Methods in molecular biology (1423). Humana Press: New York, pp. 101-118. ISBN 9781493936045 (doi: 10.1007/978-1-4939-3606-9_7)
2015
Mowat, A. (2015) Dcs tailor T cells to the tissue. Nature Reviews Immunology, 15(8), 469. (doi: 10.1038/nri3893)
2014
Scott, C. L., Murray, T. F.P. Z., Beckham, K. S.H., Douce, G. and Mowat, A. M. (2014) Signal Regulatory Protein alpha (SIRPα) regulates the homeostasis of CD103+CD11b+DCs in the intestinal lamina propria. European Journal of Immunology, 44(12), pp. 3658-3668. (doi: 10.1002/eji.201444859) (PMID:25236797) (PMCID:PMC4284040)
Bain, C. C., Bravo-Blas, A., Scott, C. L., Gomez Perdiguero, E., Geissmann, F., Henri, S., Malissen, B., Osborne, L. C., Artis, D. and Mowat, A. M. (2014) Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice. Nature Immunology, 15(10), pp. 929-937. (doi: 10.1038/ni.2967)
Bain, C. C. and Mowat, A. M. (2014) The monocyte-macrophage axis in the intestine. Cellular Immunology, 291(1-2), pp. 41-48. (doi: 10.1016/j.cellimm.2014.03.012)
Bain, C. C. and Mowat, A. M. (2014) Macrophages in intestinal homeostasis and inflammation. Immunological Reviews, 260(1), pp. 102-117. (doi: 10.1111/imr.12192)
Cerovic, V., Bain, C. C., Mowat, A. M. and Milling, S. W.F. (2014) Intestinal macrophages and dendritic cells: what's the difference? Trends in Immunology, 35(6), pp. 270-277. (doi: 10.1016/j.it.2014.04.003)
Cerovic, V. et al. (2014) Lymph borne CD8α+ DCs are uniquely able to cross-prime CD8+ T cells with antigen acquired from intestinal epithelial cells. Mucosal Immunology, 8(1), pp. 38-48. (doi: 10.1038/mi.2014.40)
Martin, J.C.J. et al. (2014) Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunology, 7(1), pp. 101-113. (doi: 10.1038/mi.2013.28)
Mattei, F. et al. (2014) The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration. PLoS ONE, 9(8), e105429. (doi: 10.1371/journal.pone.0105429) (PMID:25137049) (PMCID:PMC4138162)
Mowat, A. M. and Agace, W. W. (2014) Regional specialization within the intestinal immune system. Nature Reviews Immunology, 14(10), pp. 667-685. (doi: 10.1038/nri3738)
Mowat, A. M. (2014) Dendritic Cells Decide CD8+ T Cell Fate. Immunity, 40(3), pp. 311-312. (doi: 10.1016/j.immuni.2014.02.011)
Scott, C.L. et al. (2014) CCR2+CD103− intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells. Mucosal Immunology, 8(2), pp. 327-339. (doi: 10.1038/mi.2014.70)
2013
Bain, C.C., Scott, C.L., Uronen-Hansson, H., Gudjonsson, S., Jansson, O., Grip, O., Guilliams, M., Malissen, B., Agace, W.W. and Mowat, A.M. (2013) Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors. Mucosal Immunology, 6(3), pp. 498-510. (doi: 10.1038/mi.2012.89) (PMID:22990622) (PMCID:PMC3629381)
Cerovic, V., Houston, S., Scott, C., Aumeunier, A., Yrlid, U., Mowat, A. and Milling, S. (2013) Intestinal CD103 − dendritic cells migrate in lymph and prime effector T cells. Mucosal Immunology, 6(1), pp. 104-113. (doi: 10.1038/mi.2012.53)
Persson, E.K., Scott, C.L., Mowat, A.M. and Agace, W. W. (2013) Dendritic cell subsets in the intestinal lamina propria: ontogeny and function. European Journal of Immunology, 43(12), pp. 3098-3107. (doi: 10.1002/eji.201343740)
2012
Tamoutounour, S. et al. (2012) CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis. European Journal of Immunology, 42(12), pp. 3150-3166. (doi: 10.1002/eji.201242847)
Bain, C.C. and Mowat, A.M. (2012) CD200 receptor and macrophage function in the intestine. Immunobiology, 217(6), pp. 643-651. (doi: 10.1016/j.imbio.2011.11.004)
Pabst, O. and Mowat, A.M. (2012) Oral tolerance to food protein. Mucosal Immunology, 5(3), pp. 232-239. (doi: 10.1038/mi.2012.4)
Semmrich, M., Plantinga, M., Svensson-Frej, M., Uronen-Hansson, H., Gustafsson, T., Mowat, A.M., Yrlid, U., Lambrecht, B.N. and Agace, W.W. (2012) Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses. Mucosal Immunology, 5(2), pp. 150-160. (doi: 10.1038/mi.2011.61)
2011
Scott, C. L., Aumeunier, A. M. and Mowat, A. M. (2011) Intestinal CD103+ dendritic cells: master regulators of tolerance? Trends in Immunology, 32(9), pp. 412-419. (doi: 10.1016/j.it.2011.06.003) (PMID:21816673)
Bain, C.C. and Mowat, A.M. (2011) Intestinal macrophages - specialised adaptation to a unique environment. European Journal of Immunology, 41(9), pp. 2494-2498. (doi: 10.1002/eji.201141714)
Mowat, A. (2011) Innate immunity in the intestine. Journal of Innate Immunity, 3(6), pp. 541-542. (doi: 10.1159/000333043)
Mowat, A.M. and Bain, C.C. (2011) Mucosal macrophages in intestinal homeostasis and inflammation. Journal of Innate Immunity, 3(6), pp. 550-564. (doi: 10.1159/000329099)
2010
Geissmann, F., Gordon, S., Hume, D.A., Mowat, A.M. and Randolph, G.J. (2010) Unravelling mononuclear phagocyte heterogeneity. Nature Reviews Immunology, 10(6), pp. 453-460. (doi: 10.1038/nri2784)
Mowat, A. M. (2010) Does TLR2 regulate intestinal inflammation? European Journal of Immunology, 40(2), pp. 318-320. (doi: 10.1002/eji.200940232)
Platt, A.M., Bain, C.C., Bordon, Y., Sester, D.P. and Mowat, A.M. (2010) An Independent Subset of TLR Expressing CCR2-Dependent Macrophages Promotes Colonic Inflammation. Journal of Immunology, 184(12), pp. 6843-6854. (doi: 10.4049/jimmunol.0903987)
2009
Bordon, Y., Hansell, C. A. H., Sester, D. P., Clarke, M. , Mowat, A. M. and Nibbs, R. J. B. (2009) The atypical chemokine receptor D6 contributes to the development of experimental colitis. Journal of Immunology, 182(8), pp. 5032-5040. (doi: 10.4049/jimmunol.0802802)
2008
Robson, N. C., Donachie, A. M. and Mowat, A. M. (2008) Simultaneous presentation and cross-presentation of immune-stimulating complex-associated cognate antigen by antigen-specific B cells. European Journal of Immunology, 38(5), pp. 1238-1246. (doi: 10.1002/eji.200737758) (PMID:18398931)
Monteleone, I., Platt, A., Jaensson, E., Agace, W. and Mowat, A. (2008) IL-10-dependent partial refractoriness to Toll-like receptor stimulation modulates gut mucosal dendritic cell function. European Journal of Immunology, 38(6), pp. 1533-1547. (doi: 10.1002/eji.200737909)
Platt, A. and Mowat, A. (2008) Mucosal macrophages and the regulation of immune responses in the intestine. Immunology Letters, 119(1-2), pp. 22-31.
2007
Morton, A., McManus, B., Garside, P., Mowat, A. and Harnett, M. (2007) Inverse Rap1 and phospho-ERK expression discriminate the maintenance phase of tolerance and priming of antigen-specific CD4(+) T cells in vitro and in vivo. Journal of Immunology, 179(12), pp. 8026-8034.
2006
Helgeby, A., Robson, N. C., Donachie, A. M., Beackock-Sharp, H., Lövgren, K., Schön, K., Mowat, A. M. and Lycke, N. Y. (2006) The combined CTA1-DD/ISCOM adjuvant vector promotes priming of mucosal and systemic immunity to incorporated antigens by specific targeting of B cells. Journal of Immunology, 176(6), pp. 3697-3706. (doi: 10.4049/jimmunol.176.6.3697) (PMID:16517738)
Aguila, A., Donachie, A. M., Peyre, M., McSharry, C. P., Sesardic, D. and Mowat, A. M. (2006) Induction of protective and mucosal immunity against diphtheria by a immune stimulating complex (ISCOMS) based vaccine. Vaccine, 24, pp. 5201-5210. (doi: 10.1016/j.vaccine.2006.03.081) (PMID:16650917)
Mowat, A. and Strobel, S. (2006) Oral tolerance and allergic responses to food proteins. Current Opinion in Allergy and Clinical Immunology, 6, pp. 207-213.
2005
Beacock-Sharp, H., Chirdo, F., Millington, O. and Mowat, A. (2005) Immunomodulatory dendritic cells in intestinal lamina propria. European Journal of Immunology, 35(6), pp. 1831-1840.
Grierson, A., Mitchell, P., Adams, C., Mowat, A., Brewer, J., Harnett, M. and Garside, P. (2005) Direct quantitation of T cell signaling by laser scanning cytometry. Journal of Immunological Methods, 301, pp. 140-153. (doi: 10.1016/j.jim.2005.04.011)
Mowat, A. (2005) Dendritic cells and immune responses to orally administered antigens. Vaccine, 23, pp. 1797-1799. (doi: 10.1016/j.vaccine.2004.11.008)
2004
Adams, C., Grierson, A., Mowat, A., Harnett, M. and Garside, P. (2004) Differences in the kinetics, amplitude, and localization of ERK activation in anergy and priming revealed at the level of individual primary T cells by laser scanning cytometry. Journal of Immunology, 173, pp. 1579-1586.
Chirdo, F., Millington, O. and Mowat, A. (2004) Anatomical and cellular basis of immunity and tolerance in the intestine. Journal of Pediatric Gastroenterology and Nutrition, 39, S723-S724.
Church, N., Dallal, H., Fullarton, G., Johnston, D., Masson, J., Mowat, A., Palmer, K., Prescott, R., Radin, E. and Turner, M. (2004) Discussion on a randomized trial comparing heater probe plus thrombin with heater probe plus placebo for bleeding peptic ulcer - Reply. Gastroenterology, 126(3), p. 940.
Courtois, P., Graham, S., Malaisse, W., Mowat, A., Rozing, J. and Scott, F. (2004) Enteropathy precedes type 1 diabetes in the BB rat. Gut, 53, pp. 1437-1444. (doi: 10.1136/gut.2004.042481)
Millington, O., Mowat, A. and Garside, P. (2004) Induction of bystander suppression by feeding antigen occurs despite normal clonal expansion of the bystander T cell population. Journal of Immunology, 173, pp. 6059-6064.
Millington, O., Wei, X., Garside, P. and Mowat, A. (2004) Interleukin-15 is not required for the induction or maintenance of orally induced peripheral tolerance. Immunology, 113, pp. 304-309. (doi: 10.1111/j.1365-2567.2004.01965.x)
Smith, K., Brewer, J., Mowat, A., Ron, Y. and Garside, P. (2004) The influence of follicular migration on T-cell differentiation. Immunology, 111, pp. 248-251. (doi: 10.1111/j.1365-2567.2004.01813.x)
2003
Robson, N. C., Beacock-Sharp, H., Donachie, A. M. and Mowat, A. M. (2003) The role of antigen-presenting cells and interleukin-12 in the priming of antigen-specific CD4+ T cells by immune stimulating complexes. Immunology, 110(1), pp. 95-104. (doi: 10.1046/j.1365-2567.2003.01705.x) (PMID:12941146)
Robson, N. C., Beacock-Sharp, H., Donachie, A. M. and Mowat, A. M. (2003) Dendritic cell maturation enhances CD8+ T-cell responses to exogenous antigen via a proteasome-independent mechanism of major histocompatibility complex class I loading. Immunology, 109(3), pp. 374-383. (doi: 10.1046/j.1365-2567.2003.01664.x) (PMID:12807483)
Beacock-Sharp, H., Donachie, A. M., Robson, N. C. and Mowat, A. M. (2003) A role for dendritic cells in the priming of antigen-specific CD4+ and CD8+ T lymphocytes by immune-stimulating complexes in vivo. International Immunology, 15(6), pp. 711-720. (doi: 10.1093/intimm/dxg067) (PMID:12750355)
Beacock-Sharp, H., Donachie, A., Mowat, A. and Robson, N. (2003) Dendritic cell maturation enhances CD8(+) T-cell responses to exogenous antigen via a proteasome-independent mechanism of major histocompatibility complex class I loading. Immunology, 109, pp. 374-383.
Mowat, A.M., Donachie, A.M., Parker, L.A., Robson, N.C., Beacock-Sharp, H., McIntyre, L.J., Millington, O. and Chirdo, F. (2003) The role of dendritic cells in regulating mucosal immunity and tolerance. Novartis Foundation Symposium, 252, pp. 291-302. (PMID:14609226)
Mowat, A. (2003) Anatomical basis of tolerance and immunity to intestinal antigens. Nature Reviews Immunology, 3(4), pp. 331-341.
Mowat, A. (2003) Coeliac disease - a meeting point for genetics, immunology, and protein chemistry. Lancet, 361, pp. 1290-1292.
2002
Furrie, E., Mowat, A., Smith, R., Strobel, S. and Turner, M. (2002) Induction of local innate immune responses and modulation of antigen uptake as mechanisms underlying the mucosal adjuvant properties of immune stimulating complexes (ISCOMS). Vaccine, 20, pp. 2254-2262.
2001
Garside, P. and Mowat, A. (2001) Oral tolerance. Seminars in Immunology, 13, pp. 177-185. (doi: 10.1006/smim.2001.0310)
Mowat, A. M.I., Donachie, A. M., Jagewall, S., Schon, K., Lowenadler, B., Dalsgaard, K., Kaastrup, P. and Lycke, N. (2001) CTA1-DD-Immune stimulating complexes: A novel, rationally designed combined mucosal vaccine adjuvant effective with nanogram doses of antigen. Journal of Immunology, 167(6), pp. 3398-3405. (doi: 10.4049/jimmunol.167.6.3398) (PMID:11544331)
Smith, R.E., Donachie, A.M., McLaren, F.H. and Mowat, A. M. (2001) Preservation of mucosal and systemic adjuvant properties of ISCOMS in the absence of functional interleukin-4 or interferon-γ. Immunology, 93(4), pp. 556-562. (doi: 10.1046/j.1365-2567.1998.00469.x)
1999
Grdic, D., Smith, R., Donachie, A., Kjerrulf, M., Hörnquist, E., Mowat, A. and Lycke, N. (1999) The mucosal adjuvant effects of cholera toxin and immune-stimulating complexes differ in their requirement for IL-12, indicating different pathways of action. European Journal of Immunology, 29(6), pp. 1774-1784. (doi: 10.1002/(SICI)1521-4141(199906)29:06<1774::AID-IMMU1774>3.0.CO;2-1) (PMID:10382739)
Mowat, A. M., Smith, R. E., Donachie, A. M., Furrie, E., Grdic, D. and Lycke, N. (1999) Oral vaccination with immune stimulating complexes. Immunology Letters, 65(1-2), pp. 133-140. (doi: 10.1016/S0165-2478(98)00136-9)
Smith, R. E., Donachie, A. M., Grdic, D., Lycke, N. and Mowat, A. M. (1999) Immune-stimulating complexes induce an IL-12-dependent cascade of innate immune responses. Journal of Immunology, 162(9), pp. 5536-5546.
1998
Smith, R. E., Donachie, A. M. and Mowat, A. M. (1998) Immune stimulating complexes as mucosal vaccines. Immunology and Cell Biology, 76(3), pp. 263-269. (doi: 10.1046/j.1440-1711.1998.00749.x)
1995
O'Hagan, D.T., Jeffery, H., Maloy, K.J. , Mowat, A.M., Rahman, D. and Challacombe, S.J. (1995) Biodegradable microparticles as oral vaccines. Advances in Experimental Medicine and Biology, 371B, pp. 1463-1467. (PMID:7502838)
Maloy, K. J. , Donachie, A. M. and Mowat, A. M. (1995) Induction of Th1 and Th2 CD4+ T cell responses by oral or parenteral immunization with ISCOMS. European Journal of Immunology, 25(10), pp. 2835-2841. (doi: 10.1002/eji.1830251019) (PMID:7589080)
1994
Maloy, K.J. , Donachie, A.M., O'Hagan, D.T. and Mowat, A.M. (1994) Induction of mucosal and systemic immune responses by immunization with ovalbumin entrapped in poly(lactide-co-glycolide) microparticles. Immunology, 81(4), pp. 661-667. (PMID:7518802)
1993
Mowat, A.M., Maloy, K.J. and Donachie, A.M. (1993) Immune-stimulating complexes as adjuvants for inducing local and systemic immunity after oral immunization with protein antigens. Immunology, 80(4), pp. 527-534. (PMID:7508416) (PMCID:PMC1422256)
O'Hagan, D.T., McGee, J.P., Holmgren, J., Mowat, A. M., Donachie, A.M., Mills, K.H.G., Gaisford, W., Rahman, D. and Challacombe, S.J. (1993) Biodegradable microparticles for oral immunization. Vaccine, 11(2), pp. 149-154. (doi: 10.1016/0264-410X(93)90011-L) (PMID:843861)
1991
Maloy, K.J. , Mowat, A. M., Zamoyska, R. and Crispe, I.N. (1991) Phenotypic heterogeneity of intraepithelial T lymphocytes from mouse small intestine. Immunology, 72(4), pp. 555-562. (PMID:2037315) (PMCID:PMC1384377)
Mowat, A.M., Donachie, A.M., Reid, G. and Jarrett, O. (1991) Immune-stimulating complexes containing Quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route. Immunology, 72(3), pp. 317-322. (PMID:2026440) (PMCID:PMC1384389)
Mowat, A. M. and Donachie, A.M. (1991) Studies on the immunogenicity of an endogenously processed protein antigen in mice. Immunology Letters, 27(3), pp. 243-249. (doi: 10.1016/0165-2478(91)90159-8)
Mowat, A. M. and Donachie, A. M. (1991) ISCOMS — a novel strategy for mucosal immunization? Immunology Today, 12(11), pp. 383-385. (doi: 10.1016/0167-5699(91)90133-E) (PMID:1786069)
1983
Mowat, A.M., Tait, R.C. , MacKenzie, S., Davies, M.D. and Parrott, D.M. (1983) Analysis of natural killer effector and suppressor activity by intraepithelial lymphocytes from mouse small intestine. Clinical and Experimental Immunology, 52(1), pp. 191-198. (PMID:6222852)
Articles
Pærregaard, S. I. et al. (2023) The small and large intestine contain related mesenchymal subsets that derive from embryonic Gli1+ precursors. Nature Communications, 14, 2307. (doi: 10.1038/s41467-023-37952-5) (PMID:37085516) (PMCID:PMC10121680)
Luda, K. M., Da Silva, C., Ahmadi, F., Mowat, A. M., Ohno, H., Kotarsky, K. and Agace, W. W. (2022) Identification and characterization of murine glycoprotein 2‐expressing intestinal dendritic cells. Scandinavian Journal of Immunology, 96(5), e13219. (doi: 10.1111/sji.13219)
Johnson, S. A. et al. (2021) Monocytes mediate Salmonella Typhimurium-induced tumor growth inhibition in a mouse melanoma model. European Journal of Immunology, 51(12), pp. 3228-3238. (doi: 10.1002/eji.202048913) (PMID:34633664) (PMCID:PMC9214623)
Wright, P. B. et al. (2021) The mannose receptor (CD206) identifies a population of colonic macrophages in health and inflammatory bowel disease. Scientific Reports, 11, 19616. (doi: 10.1038/s41598-021-98611-7) (PMID:34608184) (PMCID:PMC8490356)
Mowat, A. M. and Bain, C. C. (2021) Guardians of the epithelium: macrophages protect against toxic fungal derivatives. Mucosal Immunology, 14(3), pp. 542-543. (doi: 10.1038/s41385-020-00369-0) (PMID:33495494) (PMCID:PMC8076022)
Mowat, A. M. (2021) Historical perspective: Metchnikoff and the intestinal microbiome. Journal of Leukocyte Biology, 109(3), pp. 513-517. (doi: 10.1002/JLB.4RI0920-599) (PMID:33630385)
Scott, N. A. et al. (2018) Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis. Science Translational Medicine, 10(464), eaao4755. (doi: 10.1126/scitranslmed.aao4755) (PMID:30355800) (PMCID:PMC6548564)
Thomson, C. A., van de Pavert, S. A., Stakenborg, M., Labeeuw, E., Matteoli, G., Mowat, A. M. and Nibbs, R. J.B. (2018) Expression of the atypical chemokine receptor ACKR4 identifies a novel population of intestinal submucosal fibroblasts that preferentially expresses endothelial cell regulators. Journal of Immunology, 201(1), pp. 215-229. (doi: 10.4049/jimmunol.1700967) (PMID:29760193) (PMCID:PMC6013047)
Kumawat, A. K., Yu, C., Mann, E. A., Schridde, A., Finnemann, S. C. and Mowat, A. M. (2018) Expression and characterisation of αvβ5 integrin on intestinal macrophages. European Journal of Immunology, 48(7), pp. 1181-1187. (doi: 10.1002/eji.201747318) (PMID:29676784) (PMCID:PMC6207937)
Bain, C. C., Oliphant, C. J., Thomson, C. A., Kullberg, M. C. and Mowat, A. M. (2018) Pro-inflammatory role of monocyte-derived CX3CR1int macrophages in Helicobacter hepaticus-induced colitis. Infection and Immunity, 86(2), e00579-17. (doi: 10.1128/IAI.00579-17) (PMID:29203542) (PMCID:PMC5778360)
Mowat, A. M. (2018) To respond or not to respond - a personal perspective of intestinal tolerance. Nature Reviews Immunology, 18, pp. 405-415. (doi: 10.1038/s41577-018-0002-x) (PMID:29491358)
Mowat, A. M. (2017) Janus-like monocytes regulate postoperative ileus. Gut, 66(12), pp. 2049-2050. (doi: 10.1136/gutjnl-2017-314360) (PMID:28615300)
Mowat, A. M., Scott, C. L. and Bain, C. C. (2017) Barrier-tissue macrophages: functional adaptation to environmental challenges. Nature Medicine, 23(11), pp. 1258-1270. (doi: 10.1038/nm.4430) (PMID:29117177)
Bain, C.C. et al. (2017) TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine. Nature Communications, 8, 620. (doi: 10.1038/s41467-017-00658-6) (PMID:28931816) (PMCID:PMC5607002)
Joeris, T., Müller-Luda, K., Agace, W.W. and Mowat, A. M. (2017) Diversity and functions of intestinal mononuclear phagocytes. Mucosal Immunology, 10(4), pp. 845-864. (doi: 10.1038/mi.2017.22) (PMID:28378807)
Mowat, A. M. and Bain, C. C. (2017) Alternative monocytes settle in for the long term. Nature Immunology, 18(6), pp. 599-600. (doi: 10.1038/ni.3749) (PMID:28518159)
Schridde, A. et al. (2017) Tissue-specific differentiation of colonic macrophages requires TGFβ receptor-mediated signaling. Mucosal Immunology, 10, pp. 1387-1399. (doi: 10.1038/mi.2016.142) (PMID:28145440) (PMCID:PMC5417360)
Araya, R. E., Gomez Castro, M. F., Carasi, P., McCarville, J. L., Jury, J., Mowat, A. M., Verdu, E. F. and Chirdo, F. G. (2016) Mechanisms of innate immune activation by gluten peptide p31-43 in mice. American Journal of Physiology: Gastrointestinal and Liver Physiology, 311(1), G40-G49. (doi: 10.1152/ajpgi.00435.2015) (PMID:27151946)
Veenbergen, S. et al. (2016) Colonic tolerance develops in the iliac lymph nodes and can be established independent of CD103+ dendritic cells. Mucosal Immunology, 9(4), pp. 894-906. (doi: 10.1038/mi.2015.118) (PMID:26577569) (PMCID:PMC4871788)
Bain, C. C. et al. (2016) Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities. Nature Communications, 7, ncomms1185. (doi: 10.1038/ncomms11852) (PMID:27292029) (PMCID:PMC4910019)
Houston, S.A., Cerovic, V., Thomson, C., Brewer, J. , Mowat, A.M. and Milling, S. (2016) The lymph nodes draining the small intestine and colon are anatomically separate and immunologically distinct. Mucosal Immunology, 9(2), pp. 468-478. (doi: 10.1038/mi.2015.77) (PMID:26329428)
Mowat, A. (2015) Dcs tailor T cells to the tissue. Nature Reviews Immunology, 15(8), 469. (doi: 10.1038/nri3893)
Scott, C. L., Murray, T. F.P. Z., Beckham, K. S.H., Douce, G. and Mowat, A. M. (2014) Signal Regulatory Protein alpha (SIRPα) regulates the homeostasis of CD103+CD11b+DCs in the intestinal lamina propria. European Journal of Immunology, 44(12), pp. 3658-3668. (doi: 10.1002/eji.201444859) (PMID:25236797) (PMCID:PMC4284040)
Bain, C. C., Bravo-Blas, A., Scott, C. L., Gomez Perdiguero, E., Geissmann, F., Henri, S., Malissen, B., Osborne, L. C., Artis, D. and Mowat, A. M. (2014) Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice. Nature Immunology, 15(10), pp. 929-937. (doi: 10.1038/ni.2967)
Bain, C. C. and Mowat, A. M. (2014) The monocyte-macrophage axis in the intestine. Cellular Immunology, 291(1-2), pp. 41-48. (doi: 10.1016/j.cellimm.2014.03.012)
Bain, C. C. and Mowat, A. M. (2014) Macrophages in intestinal homeostasis and inflammation. Immunological Reviews, 260(1), pp. 102-117. (doi: 10.1111/imr.12192)
Cerovic, V., Bain, C. C., Mowat, A. M. and Milling, S. W.F. (2014) Intestinal macrophages and dendritic cells: what's the difference? Trends in Immunology, 35(6), pp. 270-277. (doi: 10.1016/j.it.2014.04.003)
Cerovic, V. et al. (2014) Lymph borne CD8α+ DCs are uniquely able to cross-prime CD8+ T cells with antigen acquired from intestinal epithelial cells. Mucosal Immunology, 8(1), pp. 38-48. (doi: 10.1038/mi.2014.40)
Martin, J.C.J. et al. (2014) Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunology, 7(1), pp. 101-113. (doi: 10.1038/mi.2013.28)
Mattei, F. et al. (2014) The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration. PLoS ONE, 9(8), e105429. (doi: 10.1371/journal.pone.0105429) (PMID:25137049) (PMCID:PMC4138162)
Mowat, A. M. and Agace, W. W. (2014) Regional specialization within the intestinal immune system. Nature Reviews Immunology, 14(10), pp. 667-685. (doi: 10.1038/nri3738)
Mowat, A. M. (2014) Dendritic Cells Decide CD8+ T Cell Fate. Immunity, 40(3), pp. 311-312. (doi: 10.1016/j.immuni.2014.02.011)
Scott, C.L. et al. (2014) CCR2+CD103− intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells. Mucosal Immunology, 8(2), pp. 327-339. (doi: 10.1038/mi.2014.70)
Bain, C.C., Scott, C.L., Uronen-Hansson, H., Gudjonsson, S., Jansson, O., Grip, O., Guilliams, M., Malissen, B., Agace, W.W. and Mowat, A.M. (2013) Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors. Mucosal Immunology, 6(3), pp. 498-510. (doi: 10.1038/mi.2012.89) (PMID:22990622) (PMCID:PMC3629381)
Cerovic, V., Houston, S., Scott, C., Aumeunier, A., Yrlid, U., Mowat, A. and Milling, S. (2013) Intestinal CD103 − dendritic cells migrate in lymph and prime effector T cells. Mucosal Immunology, 6(1), pp. 104-113. (doi: 10.1038/mi.2012.53)
Persson, E.K., Scott, C.L., Mowat, A.M. and Agace, W. W. (2013) Dendritic cell subsets in the intestinal lamina propria: ontogeny and function. European Journal of Immunology, 43(12), pp. 3098-3107. (doi: 10.1002/eji.201343740)
Tamoutounour, S. et al. (2012) CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis. European Journal of Immunology, 42(12), pp. 3150-3166. (doi: 10.1002/eji.201242847)
Bain, C.C. and Mowat, A.M. (2012) CD200 receptor and macrophage function in the intestine. Immunobiology, 217(6), pp. 643-651. (doi: 10.1016/j.imbio.2011.11.004)
Pabst, O. and Mowat, A.M. (2012) Oral tolerance to food protein. Mucosal Immunology, 5(3), pp. 232-239. (doi: 10.1038/mi.2012.4)
Semmrich, M., Plantinga, M., Svensson-Frej, M., Uronen-Hansson, H., Gustafsson, T., Mowat, A.M., Yrlid, U., Lambrecht, B.N. and Agace, W.W. (2012) Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses. Mucosal Immunology, 5(2), pp. 150-160. (doi: 10.1038/mi.2011.61)
Scott, C. L., Aumeunier, A. M. and Mowat, A. M. (2011) Intestinal CD103+ dendritic cells: master regulators of tolerance? Trends in Immunology, 32(9), pp. 412-419. (doi: 10.1016/j.it.2011.06.003) (PMID:21816673)
Bain, C.C. and Mowat, A.M. (2011) Intestinal macrophages - specialised adaptation to a unique environment. European Journal of Immunology, 41(9), pp. 2494-2498. (doi: 10.1002/eji.201141714)
Mowat, A. (2011) Innate immunity in the intestine. Journal of Innate Immunity, 3(6), pp. 541-542. (doi: 10.1159/000333043)
Mowat, A.M. and Bain, C.C. (2011) Mucosal macrophages in intestinal homeostasis and inflammation. Journal of Innate Immunity, 3(6), pp. 550-564. (doi: 10.1159/000329099)
Geissmann, F., Gordon, S., Hume, D.A., Mowat, A.M. and Randolph, G.J. (2010) Unravelling mononuclear phagocyte heterogeneity. Nature Reviews Immunology, 10(6), pp. 453-460. (doi: 10.1038/nri2784)
Mowat, A. M. (2010) Does TLR2 regulate intestinal inflammation? European Journal of Immunology, 40(2), pp. 318-320. (doi: 10.1002/eji.200940232)
Platt, A.M., Bain, C.C., Bordon, Y., Sester, D.P. and Mowat, A.M. (2010) An Independent Subset of TLR Expressing CCR2-Dependent Macrophages Promotes Colonic Inflammation. Journal of Immunology, 184(12), pp. 6843-6854. (doi: 10.4049/jimmunol.0903987)
Bordon, Y., Hansell, C. A. H., Sester, D. P., Clarke, M. , Mowat, A. M. and Nibbs, R. J. B. (2009) The atypical chemokine receptor D6 contributes to the development of experimental colitis. Journal of Immunology, 182(8), pp. 5032-5040. (doi: 10.4049/jimmunol.0802802)
Robson, N. C., Donachie, A. M. and Mowat, A. M. (2008) Simultaneous presentation and cross-presentation of immune-stimulating complex-associated cognate antigen by antigen-specific B cells. European Journal of Immunology, 38(5), pp. 1238-1246. (doi: 10.1002/eji.200737758) (PMID:18398931)
Monteleone, I., Platt, A., Jaensson, E., Agace, W. and Mowat, A. (2008) IL-10-dependent partial refractoriness to Toll-like receptor stimulation modulates gut mucosal dendritic cell function. European Journal of Immunology, 38(6), pp. 1533-1547. (doi: 10.1002/eji.200737909)
Platt, A. and Mowat, A. (2008) Mucosal macrophages and the regulation of immune responses in the intestine. Immunology Letters, 119(1-2), pp. 22-31.
Morton, A., McManus, B., Garside, P., Mowat, A. and Harnett, M. (2007) Inverse Rap1 and phospho-ERK expression discriminate the maintenance phase of tolerance and priming of antigen-specific CD4(+) T cells in vitro and in vivo. Journal of Immunology, 179(12), pp. 8026-8034.
Helgeby, A., Robson, N. C., Donachie, A. M., Beackock-Sharp, H., Lövgren, K., Schön, K., Mowat, A. M. and Lycke, N. Y. (2006) The combined CTA1-DD/ISCOM adjuvant vector promotes priming of mucosal and systemic immunity to incorporated antigens by specific targeting of B cells. Journal of Immunology, 176(6), pp. 3697-3706. (doi: 10.4049/jimmunol.176.6.3697) (PMID:16517738)
Aguila, A., Donachie, A. M., Peyre, M., McSharry, C. P., Sesardic, D. and Mowat, A. M. (2006) Induction of protective and mucosal immunity against diphtheria by a immune stimulating complex (ISCOMS) based vaccine. Vaccine, 24, pp. 5201-5210. (doi: 10.1016/j.vaccine.2006.03.081) (PMID:16650917)
Mowat, A. and Strobel, S. (2006) Oral tolerance and allergic responses to food proteins. Current Opinion in Allergy and Clinical Immunology, 6, pp. 207-213.
Beacock-Sharp, H., Chirdo, F., Millington, O. and Mowat, A. (2005) Immunomodulatory dendritic cells in intestinal lamina propria. European Journal of Immunology, 35(6), pp. 1831-1840.
Grierson, A., Mitchell, P., Adams, C., Mowat, A., Brewer, J., Harnett, M. and Garside, P. (2005) Direct quantitation of T cell signaling by laser scanning cytometry. Journal of Immunological Methods, 301, pp. 140-153. (doi: 10.1016/j.jim.2005.04.011)
Mowat, A. (2005) Dendritic cells and immune responses to orally administered antigens. Vaccine, 23, pp. 1797-1799. (doi: 10.1016/j.vaccine.2004.11.008)
Adams, C., Grierson, A., Mowat, A., Harnett, M. and Garside, P. (2004) Differences in the kinetics, amplitude, and localization of ERK activation in anergy and priming revealed at the level of individual primary T cells by laser scanning cytometry. Journal of Immunology, 173, pp. 1579-1586.
Chirdo, F., Millington, O. and Mowat, A. (2004) Anatomical and cellular basis of immunity and tolerance in the intestine. Journal of Pediatric Gastroenterology and Nutrition, 39, S723-S724.
Church, N., Dallal, H., Fullarton, G., Johnston, D., Masson, J., Mowat, A., Palmer, K., Prescott, R., Radin, E. and Turner, M. (2004) Discussion on a randomized trial comparing heater probe plus thrombin with heater probe plus placebo for bleeding peptic ulcer - Reply. Gastroenterology, 126(3), p. 940.
Courtois, P., Graham, S., Malaisse, W., Mowat, A., Rozing, J. and Scott, F. (2004) Enteropathy precedes type 1 diabetes in the BB rat. Gut, 53, pp. 1437-1444. (doi: 10.1136/gut.2004.042481)
Millington, O., Mowat, A. and Garside, P. (2004) Induction of bystander suppression by feeding antigen occurs despite normal clonal expansion of the bystander T cell population. Journal of Immunology, 173, pp. 6059-6064.
Millington, O., Wei, X., Garside, P. and Mowat, A. (2004) Interleukin-15 is not required for the induction or maintenance of orally induced peripheral tolerance. Immunology, 113, pp. 304-309. (doi: 10.1111/j.1365-2567.2004.01965.x)
Smith, K., Brewer, J., Mowat, A., Ron, Y. and Garside, P. (2004) The influence of follicular migration on T-cell differentiation. Immunology, 111, pp. 248-251. (doi: 10.1111/j.1365-2567.2004.01813.x)
Robson, N. C., Beacock-Sharp, H., Donachie, A. M. and Mowat, A. M. (2003) The role of antigen-presenting cells and interleukin-12 in the priming of antigen-specific CD4+ T cells by immune stimulating complexes. Immunology, 110(1), pp. 95-104. (doi: 10.1046/j.1365-2567.2003.01705.x) (PMID:12941146)
Robson, N. C., Beacock-Sharp, H., Donachie, A. M. and Mowat, A. M. (2003) Dendritic cell maturation enhances CD8+ T-cell responses to exogenous antigen via a proteasome-independent mechanism of major histocompatibility complex class I loading. Immunology, 109(3), pp. 374-383. (doi: 10.1046/j.1365-2567.2003.01664.x) (PMID:12807483)
Beacock-Sharp, H., Donachie, A. M., Robson, N. C. and Mowat, A. M. (2003) A role for dendritic cells in the priming of antigen-specific CD4+ and CD8+ T lymphocytes by immune-stimulating complexes in vivo. International Immunology, 15(6), pp. 711-720. (doi: 10.1093/intimm/dxg067) (PMID:12750355)
Beacock-Sharp, H., Donachie, A., Mowat, A. and Robson, N. (2003) Dendritic cell maturation enhances CD8(+) T-cell responses to exogenous antigen via a proteasome-independent mechanism of major histocompatibility complex class I loading. Immunology, 109, pp. 374-383.
Mowat, A.M., Donachie, A.M., Parker, L.A., Robson, N.C., Beacock-Sharp, H., McIntyre, L.J., Millington, O. and Chirdo, F. (2003) The role of dendritic cells in regulating mucosal immunity and tolerance. Novartis Foundation Symposium, 252, pp. 291-302. (PMID:14609226)
Mowat, A. (2003) Anatomical basis of tolerance and immunity to intestinal antigens. Nature Reviews Immunology, 3(4), pp. 331-341.
Mowat, A. (2003) Coeliac disease - a meeting point for genetics, immunology, and protein chemistry. Lancet, 361, pp. 1290-1292.
Furrie, E., Mowat, A., Smith, R., Strobel, S. and Turner, M. (2002) Induction of local innate immune responses and modulation of antigen uptake as mechanisms underlying the mucosal adjuvant properties of immune stimulating complexes (ISCOMS). Vaccine, 20, pp. 2254-2262.
Garside, P. and Mowat, A. (2001) Oral tolerance. Seminars in Immunology, 13, pp. 177-185. (doi: 10.1006/smim.2001.0310)
Mowat, A. M.I., Donachie, A. M., Jagewall, S., Schon, K., Lowenadler, B., Dalsgaard, K., Kaastrup, P. and Lycke, N. (2001) CTA1-DD-Immune stimulating complexes: A novel, rationally designed combined mucosal vaccine adjuvant effective with nanogram doses of antigen. Journal of Immunology, 167(6), pp. 3398-3405. (doi: 10.4049/jimmunol.167.6.3398) (PMID:11544331)
Smith, R.E., Donachie, A.M., McLaren, F.H. and Mowat, A. M. (2001) Preservation of mucosal and systemic adjuvant properties of ISCOMS in the absence of functional interleukin-4 or interferon-γ. Immunology, 93(4), pp. 556-562. (doi: 10.1046/j.1365-2567.1998.00469.x)
Grdic, D., Smith, R., Donachie, A., Kjerrulf, M., Hörnquist, E., Mowat, A. and Lycke, N. (1999) The mucosal adjuvant effects of cholera toxin and immune-stimulating complexes differ in their requirement for IL-12, indicating different pathways of action. European Journal of Immunology, 29(6), pp. 1774-1784. (doi: 10.1002/(SICI)1521-4141(199906)29:06<1774::AID-IMMU1774>3.0.CO;2-1) (PMID:10382739)
Mowat, A. M., Smith, R. E., Donachie, A. M., Furrie, E., Grdic, D. and Lycke, N. (1999) Oral vaccination with immune stimulating complexes. Immunology Letters, 65(1-2), pp. 133-140. (doi: 10.1016/S0165-2478(98)00136-9)
Smith, R. E., Donachie, A. M., Grdic, D., Lycke, N. and Mowat, A. M. (1999) Immune-stimulating complexes induce an IL-12-dependent cascade of innate immune responses. Journal of Immunology, 162(9), pp. 5536-5546.
Smith, R. E., Donachie, A. M. and Mowat, A. M. (1998) Immune stimulating complexes as mucosal vaccines. Immunology and Cell Biology, 76(3), pp. 263-269. (doi: 10.1046/j.1440-1711.1998.00749.x)
O'Hagan, D.T., Jeffery, H., Maloy, K.J. , Mowat, A.M., Rahman, D. and Challacombe, S.J. (1995) Biodegradable microparticles as oral vaccines. Advances in Experimental Medicine and Biology, 371B, pp. 1463-1467. (PMID:7502838)
Maloy, K. J. , Donachie, A. M. and Mowat, A. M. (1995) Induction of Th1 and Th2 CD4+ T cell responses by oral or parenteral immunization with ISCOMS. European Journal of Immunology, 25(10), pp. 2835-2841. (doi: 10.1002/eji.1830251019) (PMID:7589080)
Maloy, K.J. , Donachie, A.M., O'Hagan, D.T. and Mowat, A.M. (1994) Induction of mucosal and systemic immune responses by immunization with ovalbumin entrapped in poly(lactide-co-glycolide) microparticles. Immunology, 81(4), pp. 661-667. (PMID:7518802)
Mowat, A.M., Maloy, K.J. and Donachie, A.M. (1993) Immune-stimulating complexes as adjuvants for inducing local and systemic immunity after oral immunization with protein antigens. Immunology, 80(4), pp. 527-534. (PMID:7508416) (PMCID:PMC1422256)
O'Hagan, D.T., McGee, J.P., Holmgren, J., Mowat, A. M., Donachie, A.M., Mills, K.H.G., Gaisford, W., Rahman, D. and Challacombe, S.J. (1993) Biodegradable microparticles for oral immunization. Vaccine, 11(2), pp. 149-154. (doi: 10.1016/0264-410X(93)90011-L) (PMID:843861)
Maloy, K.J. , Mowat, A. M., Zamoyska, R. and Crispe, I.N. (1991) Phenotypic heterogeneity of intraepithelial T lymphocytes from mouse small intestine. Immunology, 72(4), pp. 555-562. (PMID:2037315) (PMCID:PMC1384377)
Mowat, A.M., Donachie, A.M., Reid, G. and Jarrett, O. (1991) Immune-stimulating complexes containing Quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route. Immunology, 72(3), pp. 317-322. (PMID:2026440) (PMCID:PMC1384389)
Mowat, A. M. and Donachie, A.M. (1991) Studies on the immunogenicity of an endogenously processed protein antigen in mice. Immunology Letters, 27(3), pp. 243-249. (doi: 10.1016/0165-2478(91)90159-8)
Mowat, A. M. and Donachie, A. M. (1991) ISCOMS — a novel strategy for mucosal immunization? Immunology Today, 12(11), pp. 383-385. (doi: 10.1016/0167-5699(91)90133-E) (PMID:1786069)
Mowat, A.M., Tait, R.C. , MacKenzie, S., Davies, M.D. and Parrott, D.M. (1983) Analysis of natural killer effector and suppressor activity by intraepithelial lymphocytes from mouse small intestine. Clinical and Experimental Immunology, 52(1), pp. 191-198. (PMID:6222852)
Book Sections
Scott, C. L., Bain, C. C. and Mowat, A. M. (2017) Isolation and identification of intestinal myeloid cells. In: Clausen, B. E. and Laman, J. D. (eds.) Inflammation: Methods and Protocols. Series: Methods in molecular biology (1559). Humana Press, pp. 223-239. ISBN 9781493967841 (doi: 10.1007/978-1-4939-6786-5_15)
Scott, C. L., Wright, P. B., Milling, S. W.F. and Mowat, A. M. (2016) Isolation and identification of conventional dendritic cell subsets from the intestine of mice and men. In: Segura, E. and Onai, N. (eds.) Dendritic Cell Protocols. Series: Methods in molecular biology (1423). Humana Press: New York, pp. 101-118. ISBN 9781493936045 (doi: 10.1007/978-1-4939-3606-9_7)