Number of items: 15.
2021
Steketee, P. C., Giordani, F. , Vincent, I. M. , Crouch, K. , Achcar, F. , Dickens, N. J. , Morrison, L. J., MacLeod, A. and Barrett, M. P.
(2021)
Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole.
PLoS Neglected Tropical Diseases, 15(11),
e0009939.
(doi: 10.1371/journal.pntd.0009939)
(PMID:34752454)
(PMCID:PMC8648117)
Brooke, D. P. et al.
(2021)
Truncated S-MGBs: towards a parasite-specific and low aggregation chemotype.
RSC Medicinal Chemistry, 12(8),
pp. 1391-1401.
(doi: 10.1039/D1MD00110H)
2020
Giordani, F. et al.
(2020)
Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs.
PLoS Pathogens, 16(11),
e1008932.
(doi: 10.1371/journal.ppat.1008932)
(PMID:33141865)
(PMCID:PMC7710103)
Dickie, E. A., Giordani, F. , Gould, M. K., Maeser, P., Burri, C., Mottram, J. C. , Rao, S. P.S. and Barrett, M. P.
(2020)
New drugs for human African trypanosomiasis:a twenty first century success story.
Tropical Medicine and Infectious Disease, 5(1),
29.
(doi: 10.3390/tropicalmed5010029)
(PMID:32092897)
(PMCID:PMC7157223)
2019
Giordani, F. , Khalaf, A. I., Gillingwater, K., Munday, J. C. , de Koning, H. P. , Suckling, C. J., Barrett, M. P. and Scott, F. J.
(2019)
Novel minor groove binders cure animal African trypanosomiasis in an in vivo mouse model.
Journal of Medicinal Chemistry, 62(6),
pp. 3021-3035.
(doi: 10.1021/acs.jmedchem.8b01847)
(PMID:30763102)
2018
Begolo, D. et al.
(2018)
The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing.
PLoS Pathogens, 14(9),
e1007315.
(doi: 10.1371/journal.ppat.1007315)
(PMID:30252911)
(PMCID:PMC6173450)
Steketee, P. C. et al.
(2018)
Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei.
PLoS Neglected Tropical Diseases, 12(5),
e0006450.
(doi: 10.1371/journal.pntd.0006450)
(PMID:29758036)
(PMCID:PMC5976210)
2017
Barrett, M. P. and Giordani, F.
(2017)
Inside Doctor Livingstone: a Scottish icon's encounter with tropical disease.
Parasitology, 144(12),
pp. 1652-1662.
(doi: 10.1017/S003118201600202X)
(PMID:27928980)
Scott, F. J. et al.
(2017)
An evaluation of Minor Groove Binders as anti-fungal and anti-mycobacterial therapeutics.
European Journal of Medicinal Chemistry, 136,
pp. 561-572.
(doi: 10.1016/j.ejmech.2017.05.039)
2016
Giordani, F. , Morrison, L. J., Rowan, T. G., De Koning, H. P. and Barrett, M. P.
(2016)
The animal trypanosomiases and their chemotherapy: a review.
Parasitology, 143(14),
pp. 1862-1889.
(doi: 10.1017/S0031182016001268)
(PMID:27719692)
(PMCID:PMC5142301)
Scott, F. J., Khalaf, A. I., Giordani, F. , Wong, P. E., Duffy, S., Barrett, M. , Avery, V. M. and Suckling, C. J.
(2016)
An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics.
European Journal of Medicinal Chemistry, 116,
pp. 116-125.
(doi: 10.1016/j.ejmech.2016.03.064)
(PMID:27060763)
(PMCID:PMC4872591)
2014
Giordani, F. , Buschini, A., Baliani, A., Kaiser, M., Brun, R., Barrett, M. P. , Pellacani, C., Poli, P. and Gilbert, I. H.
(2014)
Characterization of a melamino nitroheterocycle as a potential lead for the treatment of human African trypanosomiasis.
Antimicrobial Agents and Chemotherapy, 58(10),
pp. 5747-5757.
(doi: 10.1128/AAC.01449-13)
Giordani, F. , Munde, M., Wilson, W. D., Ismail, M. A., Kumar, A., Boykin, D. W. and Barrett, M. P.
(2014)
Green fluorescent diamidines as diagnostic probes for trypanosomes.
Antimicrobial Agents and Chemotherapy, 58(3),
pp. 1793-1796.
(doi: 10.1128/AAC.02024-13)
Giordani, F. , Mwenechanya, R. and Barrett, M.
(2014)
Advances in understanding and treatment of human African trypanosomiasis: divergent diseases caused by distinct parasites.
In: Padmanabhan, S. (ed.)
Handbook of Pharmacogenomics and Stratified Medicine.
Academic Press, pp. 901-917.
ISBN 9780123868824
(doi: 10.1016/B978-0-12-386882-4.00039-6)
Khalaf, A. I., Huggan, J. K., Suckling, C. J., Gibson, C. L., Stewart, K., Giordani, F. , Barrett, M. P. , Wong, P. E., Barrack, K. L. and Hunter, W. N.
(2014)
Structure-based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1.
Journal of Medicinal Chemistry, 57(15),
pp. 6479-6494.
(doi: 10.1021/jm500483b)
This list was generated on Tue Oct 3 21:23:41 2023 BST.