Dr Edward Hutchinson
- Senior Lecturer (Virology)
telephone:
0141 330 3503
email:
Edward.Hutchinson@glasgow.ac.uk
Biography
I started working on the molecular biology of influenza viruses as a graduate student with Paul Digard at the University of Cambridge. In 2009 I moved to the University of Oxford to work on influenza with Ervin Fodor, as a postdoctoral researcher at the Sir William Dunn School of Pathology and a Junior Research Fellow at Worcester College (2010-2014), and in 2016 I set up a research group at the MRC-University of Glasgow Centre for Virus Research.
Research interests
Research Interests
I am interested in the proteins influenza viruses use to infect a host cell. My work aims to identify which viral and host proteins are important in establishing influenza infections, what they do, and how their functions can be regulated.
These are very basic aspects of influenza virus molecular biology, but despite their small size influenza viruses are more complicated than they first appear. Their tiny genomes encode a remarkable diversity of gene products, many of which are recently-discovered and poorly-described. They replicate by taking control of and subverting highly complex cellular processes. And they propagate as a complex mixture of particles, some of which rely on each other to function.
To tackle this my group uses a range of methods, including virology, molecular biology, mass spectrometry, advanced imaging and structural biology. Furter details about our research projects can be found on the Hutchinson group page.
Disclosures
I have received honoraria for work in a steering group of the Centre for Open Science (Open Practices in Influenza Research; 2021-2022) and on an advisory board for Seqirus (2022).
Further information
Pages at ORCID, Google Scholar, ResearchGate, Publons and LinkedIn.
Publications
Selected publications
Sook Yuin Ho, J. et al. (2020) Hybrid gene origination creates human-virus chimeric proteins during infection. Cell, 181(7), 1502-1517.e23. (doi: 10.1016/j.cell.2020.05.035) (PMID:32559462) (PMCID:PMC7323901)
Sims, A. et al. (2023) Superinfection exclusion creates spatially distinct influenza virus populations. PLoS Biology, 21(2), e3001941. (doi: 10.1371/journal.pbio.3001941) (PMID:36757937) (PMCID:PMC9910727)
Hawksworth, A., Jayachander, M., Hester, S., Mohammed, S. and Hutchinson, E. (2020) Proteomics as a tool for live attenuated influenza vaccine characterisation. Vaccine, 38(4), pp. 868-877. (doi: 10.1016/j.vaccine.2019.10.082) (PMID:31708181)
Slater, A., Nair, N., Suétt, R., Mac Donnchadha, R., Bamford, C., Jasim, S., Livingstone, D. and Hutchinson, E. (2022) Visualising viruses. Journal of General Virology, 103(1), 001730. (doi: 10.1099/jgv.0.001730) (PMID:35082014) (PMCID:PMC8895616)
All publications
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Disposable plasmonics assays for monitoring airborne pathogens in commercial air filters
Engineering and Physical Sciences Research Council
2022 - 2023
- The Influenza Virus Toolkit: a reagent sharing resource for influenza research
Medical Research Council
2022 - 2023
- MRC Transition Support Award CDA
Medical Research Council
2021 - 2023
- Evaluating the Feasibility of a Multi Respiratory Virus Diagnostic using Chiral Plasmonic Assays
Wellcome Trust
2021 - 2021
- Functional investigations of the influenza virus proteome
Medical Research Council
2016 - 2023
- Quinquennial Core Funds
Medical Research Council
2016 - 2021
Supervision
- Sims, Anna
MRC-CVR PhD Programme
Teaching
Level 3 Microbiology: Deputy Co-ordinator
Level 4 Molecular and Cellular Microbiology: Organising Committee
Wellcome Trust Integrative Infection Biology Doctoral Training Programme: Management Group
CVR Introduction to Virus Research: Organising Committee (chair)
Deputy Convenor of Postgraduate Research, School of Infection & Immunity
Professional activities & recognition
Prizes, awards & distinctions
- 2021: Microbiology Outreach Prize (Microbiology Society)
- 2008: New Researcher Science Communication Award (Biosciences Federation)
- 2007: Young Microbiologist of the Year (Society for General Microbiology)
Research fellowships
- 2021 - 2023: MRC Transition Support Award
- 2016 - 2021: MRC Career Development Award
- 2010 - 2014: Junior Research Fellowship, Worcester College Oxford
Grant committees & research advisory boards
- 2018 - 2026: BBSRC, Pool of Experts
- 2024 - 2026: Royal Society, Research Grants Board: Biological Sciences
- 2020 - 2021: Wellcome Trust, Covid19 Protein Production Consortium, Reviewer Pool
- 2021 - 2022: Center for Open Science, Open Practices in Influenza Research
Professional & learned societies
- 2015: Board Member, European Scientific Working Group on Influenza
- 2019 - 2023: Virus Division (Member), Microbiology Society
- 2024 - 2025: Virus Division (Chair-Elect), Microbiology Society
- 2022 - 2025: Global Partnerships and Advocacy Committee (Advocacy subcommittee), American Society for Virology
Research datasets
Visit the Hutchinson Group webpage