Dr Duncan Clark

Honorary Senior Lecturer (School of Infection & Immunity)

School of Life Sciences, University of Glasgow, Glasgow, G12 8QQ

Research interests

Human herpesvirus 6 (HHV-6), molecular diagnostics in Infection.

Publications

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Number of items: 44.

2019

Clark, D. and Wilks, M. (2019) Molecular diagnostics. In: Tong, C. Y. W., Rosmarin, C. and Sefton, A. (eds.) Tutorial Topics in Infection for the Combined Infection Training Programme. Oxford University Press, pp. 96-104. ISBN 9780198801740

2018

Yebra, G. et al. (2018) A high HIV-1 strain variability in London, UK, revealed by full-genome analysis: Results from the ICONIC project. PLoS ONE, 13(2), e0192081. (doi: 10.1371/journal.pone.0192081) (PMID:29389981) (PMCID:PMC5794160)

2017

Smit, E. et al. (2017) An association between K65R and HIV-1 subtype C viruses in patients treated with multiple NRTIs. Journal of Antimicrobial Chemotherapy, 72(7), pp. 2075-2082. (doi: 10.1093/jac/dkx091) (PMID:28379449)

2016

Clark, D.A. (2016) Clinical and laboratory features of human herpesvirus 6 chromosomal integration. Clinical Microbiology and Infection, 22(4), pp. 333-339. (doi: 10.1016/j.cmi.2015.12.022) (PMID:26802216)

Lassalle, F. et al. (2016) Islands of linkage in an ocean of pervasive recombination reveals two-speed evolution of human cytomegalovirus genomes. Virus Evolution, 2(1), vew017. (doi: 10.1093/ve/vew017)

2015

Vyas, K., Atkinson, C., Clark, D.A. and Irish, D. (2015) Comparison of five commercially available immunochromatographic tests for the detection of norovirus in faecal specimens. Journal of Hospital Infection, 91(2), pp. 176-178. (doi: 10.1016/j.jhin.2015.06.013) (PMID:26253519)

Brown, J. R. et al. (2015) Astrovirus VA1/HMO-C: an increasingly recognized neurotropic pathogen in immunocompromised patients. Clinical Infectious Diseases, 60(6), pp. 881-888. (doi: 10.1093/cid/ciu940) (PMID:25572899) (PMCID:PMC4345817)

Martineau, A. R. et al. (2015) Double-blind randomised controlled trial of vitamin D3 supplementation for the prevention of acute respiratory infection in older adults and their carers (ViDiFlu). Thorax, 70(10), pp. 953-960. (doi: 10.1136/thoraxjnl-2015-206996)

2014

Miari, V. F., Wall, G. R. and Clark, D. A. (2014) Evaluation of non-extracted genital swabs for real-time HSV PCR. Journal of Medical Virology, 87(1), pp. 125-129. (doi: 10.1002/jmv.23967) (PMID:24788593)

Ablashi, D. et al. (2014) Classification of HHV-6A and HHV-6B as distinct viruses. Archives of Virology, 159(5), pp. 863-870. (doi: 10.1007/s00705-013-1902-5) (PMID:24193951) (PMCID:PMC4750402)

Huang, Y. et al. (2014) Human telomeres that carry an integrated copy of human herpesvirus 6 are often short and unstable, facilitating release of the viral genome from the chromosome. Nucleic Acids Research, 42(1), pp. 315-327. (doi: 10.1093/nar/gkt840) (PMID:24057213) (PMCID:PMC3874159)

2013

Donaldson, C. D., Clark, D. A., Kidd, I. M., Breuer, J. and Depledge, D. D. (2013) Genome sequence of human herpesvirus 7 strain UCL-1. Genome Announcements, 1(5), e00830. (doi: 10.1128/genomeA.00830-13) (PMID:24115547) (PMCID:PMC3795217)

Halstead, F. D. et al. (2013) Universal extraction method for gastrointestinal pathogens. Journal of Medical Microbiology, 62, pp. 1535-1539. (doi: 10.1099/jmm.0.058743-0) (PMID:23831766)

2012

Groves, K. C., Bibby, D. F., Clark, D. A., Isaksen, A., Deayton, J. R., Anderson, J., Orkin, C., Stagg, A. J. and McKnight, Á. (2012) Disease progression in HIV-1–infected viremic controllers. JAIDS: Journal of Acquired Immune Deficiency Syndromes, 61(4), pp. 407-416. (doi: 10.1097/QAI.0b013e318269c414) (PMID:22902723) (PMCID:PMC3736311)

Wall, G. R., Perinpanathan, D. and Clark, D. A. (2012) Comparison of the QIAGEN artus HIV-1 QS-RGQ test with the Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 test v2.0. Journal of Clinical Virology, 55(1), pp. 62-66. (doi: 10.1016/j.jcv.2012.05.014) (PMID:22739101)

Garrett, N. J., Apea, V., Nori, A., Ushiro-Lumb, I., Oliver, A. R., Baily, G. and Clark, D. A. (2012) Comparison of the rate and size of HIV-1 viral load blips with Roche COBAS TaqMan HIV-1 versions 1.0 and 2.0 and implications for patient management. Journal of Clinical Virology, 53(4), pp. 354-355. (doi: 10.1016/j.jcv.2011.12.024) (PMID:22261125)

2011

Lee, A. V., Atkinson, C., Manuel, R. J. and Clark, D. A. (2011) Comparative evaluation of the QIAGEN QIAsymphony® SP system and bioMérieux NucliSens easyMAG automated extraction platforms in a clinical virology laboratory. Journal of Clinical Virology, 52(4), pp. 339-343. (doi: 10.1016/j.jcv.2011.08.016) (PMID:22014618)

Bibby, D. F., McElarney, I., Breuer, J. and Clark, D. A. (2011) Comparative evaluation of the seegene seeplex RV15 and real-time PCR for respiratory virus detection. Journal of Medical Virology, 83(8), pp. 1469-1475. (doi: 10.1002/jmv.22125) (PMID:21678451)

Lee, A.V., Bibby, D.F., Oakervee, H., Rohatiner, A., Ushiro-Lumb, I., Clark, D.A. and Mattes, F.M. (2011) Nosocomial transmission of parainfluenza 3 virus in hematological patients characterized by molecular epidemiology. Transplant Infectious Disease, 13(4), pp. 433-437. (doi: 10.1111/j.1399-3062.2011.00603.x) (PMID:21466639)

2010

Li, Y. T., Emery, V. C., Surah, S., Jarmulowicz, M., Sweny, P., Kidd, I. M., Griffiths, P. D. and Clark, D. A. (2010) Extensive human cytomegalovirus (HCMV) genomic DNA in the renal tubular epithelium early after renal transplantation: Relationship with HCMV DNAemia and long-term graft function. Journal of Medical Virology, 82(1), pp. 85-93. (doi: 10.1002/jmv.21662) (PMID:19950242)

2009

Sarfo, F. S., Bibby, D. F., Schwab, U., Appiah, L. T., Clark, D. A., Collini, P., Phillips, R., Green, I., Dittmar, M. and Chadwick, D. R. (2009) Inadvertent non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral therapy in dual HIV-1/2 and HIV-2 seropositive West Africans: a retrospective study. Journal of Antimicrobial Chemotherapy, 64(3), pp. 667-669. (doi: 10.1093/jac/dkp216) (PMID:19549668)

Farrell, R. A., Antony, D., Wall, G. R., Clark, D.A., Fisniku, L., Swanton, J., Khaleeli, Z., Schmierer, K., Miller, D. H. and Giovannoni, G. (2009) Humoral immune response to EBV in multiple sclerosis is associated with disease activity on MRI. Neurology, 73(1), pp. 32-38. (doi: 10.1212/WNL.0b013e3181aa29fe) (PMID:19458321) (PMCID:PMC2848585)

Tsao, E. H., Kellam, P., Sin, C. S. Y., Rasaiyaah, J., Griffiths, P. D. and Clark, D. A. (2009) Microarray-based determination of the lytic cascade of human herpesvirus 6B. Journal of General Virology, 90, pp. 2581-2591. (doi: 10.1099/vir.0.012815-0) (PMID:19625464)

Ward, K. N. and Clark, D. A. (2009) Roseoloviruses: Human Herpesviruses 6A, 6B and 7. In: Zuckerman, A. J., Banatvala, J. E., Schoub, B. D., Griffiths, P. D. and Mortimer, P. (eds.) Principles and Practice of Clinical Virology. John Wiley & Sons: Chichester, pp. 223-244. ISBN 9780470517994 (doi: 10.1002/9780470741405.ch10)

2008

Nacheva, E. P., Ward, K. N., Brazma, D., Virgili, A., Howard, J., Leong, H. N. and Clark, D. A. (2008) Human herpesvirus 6 integrates within telomeric regions as evidenced by five different chromosomal Sites. Journal of Medical Virology, 80(11), pp. 1952-1958. (doi: 10.1002/jmv.21299) (PMID:18814270)

2007

Oliver, A. R., Pereira, S. F. and Clark, D. A. (2007) Comparative evaluation of the automated Roche TaqMan real-time quantitative human immunodeficiency virus type 1 RNA PCR assay and the Roche AMPLICOR version 1.5 conventional PCR assay. Journal of Clinical Microbiology, 45(11), pp. 3616-3619. (doi: 10.1128/JCM.00221-07) (PMID:17804650) (PMCID:PMC2168503)

Ward, K. N., Leong, H. N., Thiruchelvam, A. D., Atkinson, C. E. and Clark, D. A. (2007) Human herpesvirus 6 DNA levels in cerebrospinal fluid due to primary infection differ from those due to chromosomal viral integration and have implications for diagnosis of encephalitis. Journal of Clinical Microbiology, 45(4), pp. 1298-1304. (doi: 10.1128/JCM.02115-06) (PMID:7229866) (PMCID:PMC1865851)

Nam Leong, H., Tuke, P. W., Tedder, R. S., Khanom, A. B., Eglin, R. P., Atkinson, C. E., Ward, K. N., Griffiths, P. D. and Clark, D. A. (2007) The prevalence of chromosomally integrated human herpesvirus 6 genomes in the blood of UK blood donors. Journal of Medical Virology, 79(1), pp. 45-51. (doi: 10.1002/jmv.20760) (PMID:17133548)

Emery, V. and Clark, D. (2007) HHVA, 6B, and 7: Persistence in the population, epidemiology,tTransmission. In: Arvin, A., Campadelli-Fiume, G., Mocarski, E., Moore, P. S., Roizman, B., Whitley, R. and Yamanishi, K. (eds.) Human Herpesviruses Biology, Therapy, and Immunoprophylaxis. Cambride University Press: Cambridge, pp. 875-884. ISBN 9780521827140

Kamble, R. T., Clark, D. A., Leong, H. N., Heslop, H. E., Brenner, M. K. and Carrum, G. (2007) Transmission of integrated human herpesvirus-6 in allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplantation, 40(6), pp. 563-566. (doi: 10.1038/sj.bmt.1705780) (PMID:17637686)

2006

Clark, D. A., Tsao, E. H.F., Leong, H. N., Ward, K. N., Nacheva, E. P. and Griffiths, P. D. (2006) Reply to Boutolleau et al. and Luppi et al. Journal of Infectious Diseases, 194(7), pp. 1021-1023. (doi: 10.1086/506953)

Clark, D. A. et al. (2006) Transmission of integrated human herpesvirus 6 through stem cell transplantation: implications for laboratory diagnosis. Journal of Infectious Diseases, 193(7), pp. 912-916. (doi: 10.1086/500838) (PMID:16518751)

Ward, K. N., Leong, H. N., Nacheva, E. P., Howard, J., Atkinson, C. E., Davies, N. W. S., Griffiths, P. D. and Clark, D. A. (2006) Human herpesvirus 6 chromosomal integration in immunocompetent patients results in high levels of viral DNA in blood, sera, and hair follicles. Journal of Clinical Microbiology, 44(4), pp. 1571-1574. (doi: 10.1128/JCM.44.4.1571-1574.2006) (PMID:16597897) (PMCID:PMC1448653)

2004

Tuke, P.W., Hawke, S., Griffiths, P.D. and Clark, D.A. (2004) Distribution and quantification of human herpesvirus 6 in multiple sclerosis and control brains. Multiple Sclerosis, 10(4), pp. 355-359. (PMID:15327029)

Fryer, J. F.L., Griffiths, P. D., Emery, V. C. and Clark, D. A. (2004) Susceptibility of porcine cytomegalovirus to antiviral drugs. Journal of Antimicrobial Chemotherapy, 53(6), pp. 975-980. (doi: 10.1093/jac/dkh231) (PMID:15117919)

2003

Clark, D. A., Fryer, J. F., Emery, V. C. and Griffiths, P. D. (2003) Clinical xenotransplantation. Lancet, 362(9393), p. 1421. (doi: 10.1016/S0140-6736(03)14660-0)

Clark, D.A., Fryer, J.F.L., Tucker, A.W., McArdle, P.D., Hughes, A.E., Emery, V.C. and Griffiths, P.D. (2003) Porcine cytomegalovirus in pigs being bred for xenograft organs: progress towards control. Xenotransplantation, 10(2), pp. 142-148. (doi: 10.1034/j.1399-3089.2003.01128.x) (PMID:12588647)

Clark, D. A. and Griffiths, P. D. (2003) Human herpesvirus 6: relevance of infection in the immunocompromised host. British Journal of Haematology, 120(3), pp. 384-395. (doi: 10.1046/j.1365-2141.2003.04048.x) (PMID:12580952)

2002

Silveira, L.F.G., Stewart, P.M., Thomas, M., Clark, D.A., Bouloux, P.M.G. and MacColl, G.S. (2002) Novel homozygous splice acceptor site GnRH Receptor (GnRHR) mutation: human GnRHR “knockout”. Journal of Clinical Endocrinology and Metabolism, 87(6), pp. 2973-2977. (doi: 10.1210/jcem.87.6.8535) (PMID:12050282)

2001

Fryer, J. F.L., Griffiths, P. D., Fishman, J. A., Emery, V. C. and Clark, D. A. (2001) Quantitation of porcine cytomegalovirus in pig tissues by PCR. Journal of Clinical Microbiology, 39(3), pp. 1155-1156. (doi: 10.1128/JCM.39.3.1155-1156.2001) (PMID:11230447) (PMCID:PMC87893)

2000

Ljungman, P., Wang, F.-Z., Clark, D.A., Emery, V.C., Remberger, M., Ringdén, O. and Linde, A. (2000) High levels of human herpesvirus 6 DNA in peripheral blood leucocytes are correlated to platelet engraftment and disease in allogeneic stem cell transplant patients. British Journal of Haematology, 111(3), pp. 774-781. (doi: 10.1111/j.1365-2141.2000.02422.x) (PMID:11122137)

Kidd, I. M., Clark, D. A., Sabin, C., Andrew, D., Hassan-Walker, A., Sweny, P., Griffiths, P. and Emery, V. (2000) Prospective study of human betaherpesviruses after renal transplantation: Association of human herpesvirus 7 and cytomegalovirus co-infection with cytomegalovirus disease and rejection. Transplantation, 69(11), pp. 2400-2404. (PMID:10868648)

Clark, D. A. (2000) Human herpesvirus 6. Reviews in Medical Virology, 10(3), pp. 155-173. (doi: 10.1002/(SICI)1099-1654(200005/06)10:3<155::AID-RMV277>3.0.CO;2-6) (PMID:10815027)

Mattes, F.M., McLaughlin, J.E., Emery, V.C., Clark, D.A. and Griffiths, P.D. (2000) Histopathological detection of owl's eye inclusions is still specific for cytomegalovirus in the era of human herpesviruses 6 and 7. Journal of Clinical Pathology, 53(8), pp. 612-614. (doi: 10.1136/jcp.53.8.612) (PMID:11002765) (PMCID:PMC1762915)

This list was generated on Thu Apr 25 19:16:52 2024 BST.

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