Dr Andrew MacLean

  • Sir Henry Welcome Postdoctoral Fellow (Parasitology)

Publications

List by: Type | Date

Jump to: 2022 | 2021 | 2019 | 2018
Number of items: 10.

2022

MacLean, A. E., Hayward, J. A., Huet, D., van Dooren, G. G. and Sheiner, L. (2022) The mystery of massive mitochondrial complexes: the apicomplexan respiratory chain. Trends in Parasitology, 38(12), pp. 1041-1052. (doi: 10.1016/j.pt.2022.09.008) (PMID:36302692)

Przybyla-Toscano, J., MacLean, A. E., Franceschetti, M., Liebsch, D., Vignols, F., Keech, O., Rouhier, N. and Balk, J. (2022) Protein lipoylation in mitochondria requires Fe–S cluster assembly factors NFU4 and NFU5. Plant Physiology, 188(2), pp. 997-1013. (doi: 10.1093/plphys/kiab501) (PMID:34718778) (PMCID:PMC8825329)

2021

Moseler, A. et al. (2021) The function of glutaredoxin GRXS15 is required for lipoyl-dependent dehydrogenases in mitochondria. Plant Physiology, 186(3), pp. 1507-1525. (doi: 10.1093/plphys/kiab172) (PMID:33856472)

Kimonis, V. et al. (2021) NUBPL mitochondrial disease: new patients and review of the genetic and clinical spectrum. Journal of Medical Genetics, 58(5), pp. 314-325. (doi: 10.1136/jmedgenet-2020-106846) (PMID:32518176)

Maclean, A. E., Bridges, H. R., Silva, M. F., Ding, S., Ovciarikova, J., Hirst, J. and Sheiner, L. (2021) Complexome profile of Toxoplasma gondii mitochondria identifies divergent subunits of respiratory chain complexes including new subunits of cytochrome bc1 complex. PLoS Pathogens, 17(3), e1009301. (doi: 10.1371/journal.ppat.1009301) (PMID:33651838) (PMCID:PMC7987180)

2019

Lacombe, A., Maclean, A. E., Ovciarikova, J., Tottey, J., Mühleip, A., Fernandes, P. and Sheiner, L. (2019) Identification of the Toxoplasma gondii mitochondrial ribosome, and characterisation of a protein essential for mitochondrial translation. Molecular Microbiology, 112(4), pp. 1235-1252. (doi: 10.1111/mmi.14357) (PMID:31339607) (PMCID:PMC6851545)

2018

MacLean, A. E., Kimonis, V. E. and Balk, J. (2018) Pathogenic mutations in NUBPL affect complex I activity and cold tolerance in the yeast model Yarrowia lipolytica. Human Molecular Genetics, 27(21), pp. 3697-3709. (doi: 10.1093/hmg/ddy247) (PMID:29982452) (PMCID:PMC6196649)

Bastow, E. L., Garcia de la Torre, V. S., MacLean, A. E., Green, R. T., Merlot, S., Thomine, S. and Balk, J. (2018) Vacuolar iron stores gated by NRAMP3 and NRAMP4 are the primary source of iron in germinating seeds. Plant Physiology, 177(3), pp. 1267-1276. (doi: 10.1104/pp.18.00478) (PMID:29784767)

MacLean, A. E., Hertle, A. P., Ligas, J., Bock, R., Balk, J. and Meyer, E. H. (2018) Absence of complex I Is associated with diminished respiratory chain function in European mistletoe. Current Biology, 28(10), 1614-1619.e3. (doi: 10.1016/j.cub.2018.03.036) (PMID:29731304)

Kruse, I., MacLean, A. E., Hill, L. and Balk, J. (2018) Genetic dissection of cyclic pyranopterin monophosphate biosynthesis in plant mitochondria. Biochemical Journal, 475(2), pp. 495-509. (doi: 10.1042/BCJ20170559) (PMID:29247140) (PMCID:PMC5791162)

This list was generated on Thu Dec 1 23:04:48 2022 GMT.
Jump to: Articles
Number of items: 10.

Articles

MacLean, A. E., Hayward, J. A., Huet, D., van Dooren, G. G. and Sheiner, L. (2022) The mystery of massive mitochondrial complexes: the apicomplexan respiratory chain. Trends in Parasitology, 38(12), pp. 1041-1052. (doi: 10.1016/j.pt.2022.09.008) (PMID:36302692)

Przybyla-Toscano, J., MacLean, A. E., Franceschetti, M., Liebsch, D., Vignols, F., Keech, O., Rouhier, N. and Balk, J. (2022) Protein lipoylation in mitochondria requires Fe–S cluster assembly factors NFU4 and NFU5. Plant Physiology, 188(2), pp. 997-1013. (doi: 10.1093/plphys/kiab501) (PMID:34718778) (PMCID:PMC8825329)

Moseler, A. et al. (2021) The function of glutaredoxin GRXS15 is required for lipoyl-dependent dehydrogenases in mitochondria. Plant Physiology, 186(3), pp. 1507-1525. (doi: 10.1093/plphys/kiab172) (PMID:33856472)

Kimonis, V. et al. (2021) NUBPL mitochondrial disease: new patients and review of the genetic and clinical spectrum. Journal of Medical Genetics, 58(5), pp. 314-325. (doi: 10.1136/jmedgenet-2020-106846) (PMID:32518176)

Maclean, A. E., Bridges, H. R., Silva, M. F., Ding, S., Ovciarikova, J., Hirst, J. and Sheiner, L. (2021) Complexome profile of Toxoplasma gondii mitochondria identifies divergent subunits of respiratory chain complexes including new subunits of cytochrome bc1 complex. PLoS Pathogens, 17(3), e1009301. (doi: 10.1371/journal.ppat.1009301) (PMID:33651838) (PMCID:PMC7987180)

Lacombe, A., Maclean, A. E., Ovciarikova, J., Tottey, J., Mühleip, A., Fernandes, P. and Sheiner, L. (2019) Identification of the Toxoplasma gondii mitochondrial ribosome, and characterisation of a protein essential for mitochondrial translation. Molecular Microbiology, 112(4), pp. 1235-1252. (doi: 10.1111/mmi.14357) (PMID:31339607) (PMCID:PMC6851545)

MacLean, A. E., Kimonis, V. E. and Balk, J. (2018) Pathogenic mutations in NUBPL affect complex I activity and cold tolerance in the yeast model Yarrowia lipolytica. Human Molecular Genetics, 27(21), pp. 3697-3709. (doi: 10.1093/hmg/ddy247) (PMID:29982452) (PMCID:PMC6196649)

Bastow, E. L., Garcia de la Torre, V. S., MacLean, A. E., Green, R. T., Merlot, S., Thomine, S. and Balk, J. (2018) Vacuolar iron stores gated by NRAMP3 and NRAMP4 are the primary source of iron in germinating seeds. Plant Physiology, 177(3), pp. 1267-1276. (doi: 10.1104/pp.18.00478) (PMID:29784767)

MacLean, A. E., Hertle, A. P., Ligas, J., Bock, R., Balk, J. and Meyer, E. H. (2018) Absence of complex I Is associated with diminished respiratory chain function in European mistletoe. Current Biology, 28(10), 1614-1619.e3. (doi: 10.1016/j.cub.2018.03.036) (PMID:29731304)

Kruse, I., MacLean, A. E., Hill, L. and Balk, J. (2018) Genetic dissection of cyclic pyranopterin monophosphate biosynthesis in plant mitochondria. Biochemical Journal, 475(2), pp. 495-509. (doi: 10.1042/BCJ20170559) (PMID:29247140) (PMCID:PMC5791162)

This list was generated on Thu Dec 1 23:04:48 2022 GMT.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Characterization of critical differences between human and parasite respiratory complex II
    Medical Research Council
    2022 - 2025
     
  • Elucidating the structure and function of the divergent and essential cytochrome bc1 complex in apicomplexan parasites
    Wellcome Trust
    2021 - 2024