Dr Barbara Nicholl
- Senior Lecturer (General Practice & Primary Care)
email:
Barbara.Nicholl@glasgow.ac.uk
pronouns:
She/her/hers
School of Health & Wellbeing, General Practice & Primary Care, CLARICE PEARS BUILDING, 90 BYRES ROAD, Glasgow, G12 8TB
Biography
Barbara Nicholl joined General Practice and Primary Care in July 2012 as a Lecturer. Her role here is split between research and coordination of the MSc in Primary Care, on which she also has teaching responsibilities.
Barbara’s particular interests are the management of persistent pain in primary care, the impact persistent pain has on individuals with other long term conditions (multimorbidity and treatment burden), and the relationship between physical and mental health. She supervises a number of PhD students in this field and on primary care research more generally; she also leads our online distance learning MSc in Primary Health Care.
Prior to her post here Barbara worked at Keele University on an NIHR funded cluster randomised controlled trial investigating osteoarthritis and comorbid anxiety and depressive symptoms. Barbara completed her PhD, entitled “Investigation of a multifactorial causal model for chronic widespread pain” in 2009 at the University of Manchester, which involved exploring the role of psychosocial, genetic and physical trauma factors in the onset of chronic widespread pain.
Research interests
- Epidemiology and management of persistent pain, including the relationship with and impact of persistent pain in the presence of additional physical or mental health long-term conditions
- Primary care based research including observational studies and randomised controlled trials
Publications
2024
Pacitti, C. , Cairns, D. , Ward, L. and Nicholl, B. I. (2024) Investigating pain-related medication use and contribution to polypharmacy in adults with intellectual disabilities: a systematic review. BMC Medicine, 22, 565. (doi: 10.1186/s12916-024-03770-9)
Krauth, S. J. et al. (2024) Association of latent class analysis-derived multimorbidity clusters with adverse health outcomes in patients with multiple long-term conditions: comparative results across three UK cohorts. EClinicalMedicine, 74, 102703. (doi: 10.1016/j.eclinm.2024.102703)
Politis, M., Crawford, L. , Jani, B. D. , Nicholl, B. I. , Lewsey, J. , McAllister, D. A. , Mair, F. S. and Hanlon, P. (2024) An observational analysis of frailty in combination with loneliness or social isolation and their association with socioeconomic deprivation, hospitalisation and mortality among UK Biobank participants. Scientific Reports, 14, 7258. (doi: 10.1038/s41598-024-57366-7)
Erhahiemen, P. , O'Donnell, C. A. , Gallacher, K. and Nicholl, B. I. (2024) A systematic review of the experience of treatment burden of digital health for military personnel in primary healthcare. Health Open Research, 6(9), (doi: 10.12688/healthopenres.13599.1)
Mair, F. S. et al. (2024) Developing SysteMatic: prevention, precision and equity by design for people living with multiple long-term conditions. Journal of Multimorbidity and Comorbidity, 14, pp. 1-9. (doi: 10.1177/26335565241272682)
2023
Foster, H. M.E. , Gill, J. M.R. , Mair, F. S. , Celis-Morales, C. A. , Jani, B. D. , Nicholl, B. I. , Lee, D. and O'Donnell, C. A. (2023) Social connection and mortality in UK Biobank: a prospective cohort analysis. BMC Medicine, 21, 384. (doi: 10.1186/s12916-023-03055-7) (PMID:37946218) (PMCID:PMC10637015)
Jani, B. D. , Sullivan, M. K. , Hanlon, P. , Nicholl, B. I. , Lees, J. S. , Brown, L., MacDonald, S. , Mark, P. B. , Mair, F. S. and Sullivan, F. M. (2023) Personalised lung cancer risk stratification and lung cancer screening: do general practice electronic medical records have a role? British Journal of Cancer, (doi: 10.1038/s41416-023-02467-9) (PMID:37880510) (Early Online Publication)
Rughani, G., Nilsen, T. I.L., Wood, K., Mair, F. S. , Hartvigsen, J., Mork, P. J. and Nicholl, B. I. (2023) The selfBACK artificial intelligence-based smartphone app can improve low back pain outcome even in patients with high levels of depression or stress. European Journal of Pain, 27(5), pp. 568-579. (doi: 10.1002/ejp.2080) (PMID:36680381)
Morton, F. R. , Jani, B. D. , Mair, F. S. , McLoone, P. , Canning, J., Macdonald, S. , McQueenie, R., Siebert, S. and Nicholl, B. I. (2023) Association between risk, duration and cause of hospitalisations in people with rheumatoid arthritis and multimorbidity in the UK Biobank and Scottish Early Rheumatoid Arthritis (SERA) cohorts: longitudinal observational study. Seminars in Arthritis and Rheumatism, 58, 152130. (doi: 10.1016/j.semarthrit.2022.152130) (PMID:36459724)
Hastie, C. E. , Foster, H. M.E. , Jani, B. D. , O'Donnell, C. A. , Ho, F. K., Pell, J. P. , Sattar, N. , Katikireddi, S. V. , Mair, F. S. and Nicholl, B. I. (2023) Chronic pain and COVID-19 hospitalisation and mortality: a UK Biobank cohort study. Pain, 164(1), pp. 84-90. (doi: 10.1097/j.pain.0000000000002663) (PMID:35452027) (PMCID:PMC9756431)
McLoone, P. , Jani, B. D. , Siebert, S. , Morton, F. R. , Canning, J., Macdonald, S. , Mair, F. S. and Nicholl, B. I. (2023) Classification of long-term condition patterns in rheumatoid arthritis and associations with adverse health events: a UK Biobank cohort study. Journal of Multimorbidity and Comorbidity, 13, p. 26335565221148616. (doi: 10.1177/26335565221148616) (PMID:36798088) (PMCID:PMC9926377)
Nguyen, T. N. et al. (2023) Multimorbidity and blood pressure control in patients attending primary care in Canada. Journal of Primary Care and Community Health, 14, pp. 1-9. (doi: 10.1177/21501319231215025) (PMID:38097504) (PMCID:PMC10725138)
2022
Svendsen, M. J., Nicholl, B. I. , Mair, F. S. , Wood, K., Rasmussen, C. D. N. and Stochkendahl, M. J. (2022) One size does not fit all: participants’ experiences of the selfBACK app to support self-management of low back pain—a qualitative interview study. Chiropractic and Manual Therapies, 30, 41. (doi: 10.1186/s12998-022-00452-2) (PMID:36192724) (PMCID:PMC9531397)
Canning, J., Siebert, S. , Jani, B. , Harding-Edgar, L., Kempe, I., Mair, F. S. and Nicholl, B. I. (2022) Examining the relationship between rheumatoid arthritis, multimorbidity and adverse health-related outcomes: a systematic review. Arthritis Care and Research, 74(9), pp. 1500-1512. (doi: 10.1002/acr.24587) (PMID:33650196)
Hanlon, P. , Lewsey, J. , Quint, J. K., Jani, B. D. , Nicholl, B. I. , McAllister, D. A. and Mair, F. S. (2022) Frailty in COPD: an analysis of prevalence and clinical impact using UK Biobank. BMJ Open Respiratory Research, 9, e001314. (doi: 10.1136/bmjresp-2022-001314) (PMID:35787523) (PMCID:PMC9255399)
Foster, H. M.E. et al. (2022) The association between a lifestyle score, socioeconomic status, and COVID-19 outcomes within the UK Biobank cohort. BMC Infectious Diseases, 22, 273. (doi: 10.1186/s12879-022-07132-9) (PMID:35351028) (PMCID:PMC8964028)
Hanlon, P. , Jani, B. D. , Nicholl, B. , Lewsey, J. , McAllister, D. A. and Mair, F. S. (2022) Associations between multimorbidity and adverse health outcomes in UK Biobank and the SAIL Databank: a comparison of longitudinal cohort studies. PLoS Medicine, 19(3), e1003931. (doi: 10.1371/journal.pmed.1003931) (PMID:35255092) (PMCID:PMC8901063)
Øverås, C. K., Nilsen, T. I.L., Nicholl, B. I. , Rughani, G., Wood, K., Søgaard, K., Mair, F. S. and Hartvigsen, J. (2022) Multimorbidity and co-occurring musculoskeletal pain do not modify the effect of the selfBACK app on low back pain-related disability. BMC Medicine, 10, 53. (doi: 10.1186/s12916-022-02237-z) (PMID:35130898) (PMCID:PMC8822859)
Hanlon, P. , Morton, F. , Siebert, S. , Jani, B. D. , Nicholl, B. I. , Lewsey, J. , McAllister, D. and Mair, F. S. (2022) Frailty in rheumatoid arthritis and its relationship with disease activity, hospitalisation and mortality: a longitudinal analysis of the Scottish Early Rheumatoid Arthritis cohort and UK Biobank. RMD Open, 8(1), e002111. (doi: 10.1136/rmdopen-2021-002111) (PMID:35292529) (PMCID:PMC8928366)
Svendsen, M. J. et al. (2022) Using intervention mapping to develop a decision support system–based smartphone app (selfBACK) to support self-management of nonspecific low back pain: development and usability study. Journal of Medical Internet Research, 24(1), e26555. (doi: 10.2196/26555) (PMID:35072645) (PMCID:PMC8822424)
Corcoran, N. M.E. , Mair, F. S. , Nicholl, B. , Macdonald, S. and Jani, B. D. (2022) Long-term conditions, multimorbidity and colorectal cancer risk in the UK Biobank cohort. Journal of Multimorbidity and Comorbidity, 12, p. 26335565221110123. (doi: 10.1177/26335565221110123) (PMID:36132374) (PMCID:PMC9483970)
2021
Sullivan, M. K. et al. (2021) Hospitalisation events in people with chronic kidney disease as a component of multimorbidity: parallel cohort studies in research and routine care settings. BMC Medicine, 19, 278. (doi: 10.1186/s12916-021-02147-6)
Sullivan, M. K. et al. (2021) Multimorbidity and the risk of major adverse kidney events: findings from the UK Biobank cohort. Clinical Kidney Journal, 14(11), pp. 2409-2419. (doi: 10.1093/ckj/sfab079) (PMCID:PMC8573008)
Jani, B. D. et al. (2021) Family history of diabetes and risk of SARS-COV-2 in UK Biobank: a prospective cohort study. Endocrinology, Diabetes and Metabolism, 4(4), e00283. (doi: 10.1002/edm2.283) (PMID:34505416) (PMCID:PMC8420405)
Sandal, L. F. et al. (2021) Effectiveness of app-delivered, tailored self-management support for adults with lower back pain–related disability. JAMA Internal Medicine, 181(10), pp. 1288-1296. (doi: 10.1001/jamainternmed.2021.4097) (PMID:34338710) (PMCID:PMC8329791)
Hanlon, P. , Jani, B. D. , Butterly, E., Nicholl, B. , Lewsey, J. , McAllister, D. A. and Mair, F. S. (2021) An analysis of frailty and multimorbidity in 20,566 UK Biobank participants with type 2 diabetes. Communications Medicine, 1, 28. (doi: 10.1038/s43856-021-00029-9) (PMID:35602215) (PMCID:PMC9053176)
Mutambudzi, M. et al. (2021) Occupation and risk of severe COVID-19: prospective cohort study of 120 075 UK Biobank participants. Occupational and Environmental Medicine, 78(5), pp. 307-314. (doi: 10.1136/oemed-2020-106731) (PMID:33298533)
Johnston, K. J.A. et al. (2021) Sex-stratified genome-wide association study of multisite chronic pain in UK Biobank. PLoS Genetics, 17(4), e1009428. (doi: 10.1371/journal.pgen.1009428) (PMID:33830993) (PMCID:PMC8031124)
Jani, B. D. , McQueenie, R., Nicholl, B. I. , Field, R. , Hanlon, P. , Gallacher, K. I. , Mair, F. S. and Lewsey, J. (2021) Association between patterns of alcohol consumption (beverage type, frequency and consumption with food) and risk of adverse health outcomes: a prospective cohort study. BMC Medicine, 19, 8. (doi: 10.1186/s12916-020-01878-2) (PMID:33430840) (PMCID:PMC7802201)
Marley, J., Nicholl, B. I. , Macdonald, S. , Mair, F. S. and Jani, B. D. (2021) Associations between long-term conditions and upper gastrointestinal cancer incidence: a prospective population-based cohort of UK Biobank participants. Journal of Multimorbidity and Comorbidity, 11, 2633556521. (doi: 10.1177/26335565211056136) (PMID:34820338) (PMCID:PMC8606912)
McQueenie, R., Jani, B. D. , Siebert, S. , McCowan, C. , Macdonald, S. , Mair, F. S. and Nicholl, B. I. (2021) Prevalence of chronic pain in LTCs and multimorbidity: a cross-sectional study using UK Biobank. Journal of Multimorbidity and Comorbidity, 11, p. 26335565211005870. (doi: 10.1177/26335565211005870)
2020
Svendsen, M. J., Wood, K., Kyle, J., Cooper, K., Rasmussen, C. D. N., Sandal, L. F., Stochkendahl, M. J., Mair, F. S. and Nicholl, B. I. (2020) Barriers and facilitators to patient uptake and utilisation of digital interventions for the self-management of low back pain: a systematic review of qualitative studies. BMJ Open, 10(12), e038800. (doi: 10.1136/bmjopen-2020-038800) (PMID:33310794) (PMCID:PMC7735096)
Petermann-Rocha, F. et al. (2020) Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank. BMC Medicine, 18, 355. (doi: 10.1186/s12916-020-01822-4) (PMID:33167965) (PMCID:PMC7652674)
Chiang, J. I., Furler, J., Mair, F. , Jani, B. D. , Nicholl, B. I. , Thuraisingam, S. and Manski-Nankervis, J.-A. (2020) Associations between multimorbidity and glycaemia (HbA1c) in people with type 2 diabetes: cross-sectional study in Australian general practice. BMJ Open, 10(11), e039625. (doi: 10.1136/bmjopen-2020-039625) (PMID:33243798) (PMCID:PMC7692835)
Chiang, J. I., Manski-Nankervis, J.-A., Thuraisingam, S., Jenkins, A., O'Neal, D., Mair, F. S. , Jani, B. D. , Nicholl, B. I. and Furler, J. (2020) Multimorbidity, glycaemic variability and time in target range in people with type 2 diabetes: a baseline analysis of the GP-OSMOTIC trial. Diabetes Research and Clinical Practice, 169, 108451. (doi: 10.1016/j.diabres.2020.108451) (PMID:32949650)
McQueenie, R., Nicholl, B. I. , Jani, B. D. , Canning, J., Macdonald, S. , McCowan, C. , Neary, J. , Browne, S. , Mair, F. S. and Siebert, S. (2020) Patterns of multimorbidity and their effects on adverse outcomes in rheumatoid arthritis: a study of 5658 UK Biobank participants. BMJ Open, 10(11), e038829. (doi: 10.1136/bmjopen-2020-038829) (PMID:33234629) (PMCID:PMC7684828)
Rasmussen, C. D. N., Svendsen, M. J., Wood, K., Nicholl, B. I. , Mair, F. S. , Sandal, L. F., Mork, P. J., Søgaard, K., Bach, K. and Stochkendahl, M. J. (2020) App-delivered self-management intervention trial selfBACK for people with low back pain: protocol for implementation and process evaluation. JMIR Research Protocols, 9(10), e20308. (doi: 10.2196/20308) (PMID:33118959) (PMCID:PMC7661240)
McQueenie, R. et al. (2020) Multimorbidity, polypharmacy, and COVID-19 infection within the UK Biobank cohort. PLoS ONE, 15(8), e0238091. (doi: 10.1371/journal.pone.0238091) (PMID:32817712) (PMCID:PMC7440632)
Alslamah, T., Nicholl, B. , AlslailI, F. Y., Harris, L., Melville, C. A. and Kinnear, D. (2020) Cultural adaptation of self-management of type 2 diabetes in Saudi Arabia (qualitative study). PLoS ONE, 15(7), e0232904. (doi: 10.1371/journal.pone.0232904) (PMID:32722666) (PMCID:PMC7386581)
Niedzwiedz, C. L. et al. (2020) Ethnic and socioeconomic differences in SARS-CoV-2 infection: prospective cohort study using UK Biobank. BMC Medicine, 18, 160. (doi: 10.1186/s12916-020-01640-8) (PMID:32466757) (PMCID:PMC7255908)
Chiang, J. I. et al. (2020) Multimorbidity, mortality, and HbA1c in type 2 diabetes: a cohort study with UK and Taiwanese cohorts. PLoS Medicine, 17(5), e1003094. (doi: 10.1371/journal.pmed.1003094)
Al Slamah, T., Nicholl, B. I. , Alslail, F. Y., Harris, L., Kinnear, D. and Melville, C. A. (2020) Correlates of type 2 diabetes and glycaemic control in adults in Saudi Arabia a secondary data analysis of the Saudi health interview survey. BMC Public Health, 20, 515. (doi: 10.1186/s12889-020-08597-6) (PMID:32303201) (PMCID:PMC7164173)
Hanlon, P. et al. (2020) Assessing risks of polypharmacy involving medications with anticholinergic properties. Annals of Family Medicine, 18(2), pp. 148-155. (doi: 10.1370/afm.2501) (PMID:32152019) (PMCID:PMC7062487)
Canning, J., Siebert, S. , Jani, B. D. , Mair, F. S. and Nicholl, B. I. (2020) Examining the relationship between rheumatoid arthritis, multimorbidity and adverse health-related outcomes: a systematic review protocol. Journal of Comorbidity, 10, pp. 1-5. (doi: 10.1177/2235042X20906657)
Mair, F. S. , Foster, H. M.E. and Nicholl, B. I. (2020) Multimorbidity and the COVID-19 pandemic – an urgent call to action. Journal of Comorbidity, 10, pp. 1-2. (doi: 10.1177/2235042X20961676) (PMID:33117721) (PMCID:PMC7573706)
2019
Sandal, L. F. et al. (2019) An app-delivered self-management program for people with low back pain: protocol for the selfBACK randomised controlled trial. JMIR Research Protocols, 8(12), e14720. (doi: 10.2196/14720) (PMID:31793897) (PMCID:PMC6918200)
Johnston, K. J.A., Adams, M. J., Nicholl, B. I. , Ward, J. , Strawbridge, R. , McIntosh, A., Smith, D. J. and Bailey, M. E.S. (2019) Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5. Translational Psychiatry, 9, 310. (doi: 10.1038/s41398-019-0613-4) (PMID:31748543) (PMCID:PMC6868167)
Gallacher, K. I. , Jani, B. D. , Hanlon, P. , Nicholl, B. I. and Mair, F. S. (2019) Multimorbidity in stroke. Stroke, 50(7), pp. 1919-1926. (doi: 10.1161/STROKEAHA.118.020376) (PMID:31233391)
Johnston, K. J.A., Adams, M. J., Nicholl, B. I. , Ward, J. , Strawbridge, R. , Ferguson, A., McIntosh, A., Bailey, M. E.S. and Smith, D. J. (2019) Genome-wide association study of multisite chronic pain in UK Biobank. PLoS Genetics, 15(6), e1008164. (doi: 10.1371/journal.pgen.1008164) (PMID:31194737) (PMCID:PMC6592570)
Jani, B. D. , Hanlon, P. , Nicholl, B. I. , McQueenie, R., Gallacher, K. I. , Lee, D. and Mair, F. S. (2019) Relationship between multimorbidity, demographic factors and mortality: findings from the UK Biobank Cohort. BMC Medicine, 17, 74. (doi: 10.1186/s12916-019-1305-x) (PMID:30967141) (PMCID:PMC6456941)
Bach, K., Marling, C., Mork, P. J., Aamodt, A., Mair, F. S. and Nicholl, B. I. (2019) Design of a clinician dashboard to facilitate co-decision making in the management of non-specific low back pain. Journal of Intelligent Information Systems, 52(2), pp. 269-284. (doi: 10.1007/s10844-018-0539-y)
Jani, B. et al. (2019) Evaluation of New Models of Primary Care in Scotland: Lanarkshire Case Study. Project Report. Scottish School of Primary Care.
2018
Chiang, J. I., Jani, B. D. , Mair, F. S. , Nicholl, B. I. , Furler, J., O’Neal, D., Jenkins, A., Condron, P. and Manski-Nankervis, J.-A. (2018) Associations between multimorbidity, all-cause mortality and glycaemia in people with type 2 diabetes: a systematic review. PLoS ONE, 13(12), e0209585. (doi: 10.1371/journal.pone.0209585) (PMID:30586451) (PMCID:PMC6306267)
Foster, H. M.E. , Celis-Morales, C. A. , Nicholl, B. I. , Petermann, F., Pell, J. P. , Gill, J. M.R. , O'Donnell, C. A. and Mair, F. S. (2018) The effect of socioeconomic deprivation on the association between an extended measurement of unhealthy lifestyle factors and health outcomes: a prospective analysis of the UK Biobank cohort. Lancet Public Health, 3(12), e576-e585. (doi: 10.1016/S2468-2667(18)30200-7) (PMID:30467019)
Kigozi, J. et al. (2018) Cost‐utility analysis of routine anxiety and depression screening in patients consulting for osteoarthritis: results from a clinical, randomized controlled trial. Arthritis Care and Research, 70(12), pp. 1787-1794. (doi: 10.1002/acr.23568) (PMID:29609205)
Jani, B. D. , Nicholl, B. I. , McQueenie, R., Connelly, D. T., Hanlon, P. , Gallacher, K. I. , Lee, D. and Mair, F. S. (2018) Multimorbidity and co-morbidity in atrial fibrillation and effects on survival: findings from UK Biobank cohort. Europace, 20, f329-f336. (doi: 10.1093/europace/eux322) (PMID:29112751) (PMCID:PMC6277149)
Hanlon, P. , Nicholl, B. I. , Jani, B. D. , Lee, D. , McQueenie, R. and Mair, F. S. (2018) Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective analysis of 493,737 UK Biobank participants. Lancet Public Health, 3(7), e323-e332. (doi: 10.1016/S2468-2667(18)30091-4) (PMID:29908859) (PMCID:PMC6028743)
Chiang, J. I., Furler, J., Mair, F. S. , Jani, B. , Nicholl, B. I. , Jenkins, A., Condron, P., O’Neal, D. and Manski-Nankervis, J.-A. (2018) Impact of multimorbidity count on all-cause mortality and glycaemic outcomes in people with type 2 diabetes: a systematic review protocol. BMJ Open, 8(4), e021100. (doi: 10.1136/bmjopen-2017-021100) (PMID:29626050)
Gallacher, K. I. , McQueenie, R., Nicholl, B. , Jani, B. D. , Lee, D. and Mair, F. S. (2018) Risk factors and mortality associated with multimorbidity in people with stroke or transient ischaemic attack: a study of 8,751 UK Biobank participants. Journal of Comorbidity, 8(1), pp. 1-8. (doi: 10.15256/joc.2018.8.129)
Hanlon, P. , Nicholl, B. I. , Jani, B. D. , McQueenie, R., Lee, D. , Gallacher, K. I. and Mair, F. S. (2018) Examining patterns of multimorbidity, polypharmacy and risk of adverse drug reactions in chronic obstructive pulmonary disease: a cross-sectional UK Biobank study. BMJ Open, 8(1), e018404. (doi: 10.1136/bmjopen-2017-018404) (PMID:29332840) (PMCID:PMC5781016)
2017
Al Slamah, T., Nicholl, B. I. , Alslail, F. Y. and Melville, C. A. (2017) Self-management of type 2 diabetes in Gulf Cooperation Council countries: a systematic review. PLoS ONE, 12(12), e0189160. (doi: 10.1371/journal.pone.0189160) (PMID:29232697) (PMCID:PMC5726716)
Nicholl, B. et al. (2017) Digital support interventions for the self-management of low back pain: a systematic review. Journal of Medical Internet Research, 19(5), e179. (doi: 10.2196/jmir.7290) (PMID:28550009)
Mallen, C. D. et al. (2017) The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care. PLoS Medicine, 14(4), e1002273. (doi: 10.1371/journal.pmed.1002273) (PMID:28399129) (PMCID:PMC5388468)
2016
Mundal, I., Bjørngaard, J. H., Nilsen, T. I.L., Nicholl, B. I. , Gråwe, R. W. and Fors, E. A. (2016) Long-term changes in musculoskeletal pain sites in the general population: the HUNT study. Journal of Pain, 17(11), pp. 1246-1256. (doi: 10.1016/j.jpain.2016.08.006) (PMID:27578444)
McIntosh, A. M. et al. (2016) Genetic and environmental risk for chronic pain and the contribution of risk variants for major depressive disorder: a family-based mixed-model analysis. PLoS Medicine, 13(8), e1002090. (doi: 10.1371/journal.pmed.1002090) (PMID:27529168) (PMCID:PMC4987025)
Clarson, L.E., Nicholl, B.I. , Bishop, A., Daniel, R. and Mallen, C.D. (2016) Discussing prognosis with patients with osteoarthritis: a cross-sectional survey in general practice. Clinical Rheumatology, 35(4), pp. 1011-1017. (doi: 10.1007/s10067-015-3094-8) (PMID:26474771)
Martin, D. J. et al. (2016) Cardiometabolic disease and features of depression and bipolar disorder: population-based, cross-sectional study. British Journal of Psychiatry, 208(4), pp. 343-351. (doi: 10.1192/bjp.bp.114.157784) (PMID:26795427)
Smith, D.J. et al. (2016) Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci. Molecular Psychiatry, 21(6), pp. 749-757. (doi: 10.1038/mp.2016.49) (PMID:27067015)
2015
Cullen, B. et al. (2015) Cognitive function and lifetime features of depression and bipolar disorder in a large population sample: Cross-sectional study of 143,828 UK Biobank participants. European Psychiatry, 30(8), pp. 950-958. (doi: 10.1016/j.eurpsy.2015.08.006) (PMID:26647871)
Jani, B. D. , McLean, G., Nicholl, B. I. , Barry, S. J.E. , Sattar, N. , Mair, F. S. and Cavanagh, J. (2015) Risk assessment and predicting outcomes in patients with depressive symptoms: a review of potential role of peripheral blood based biomarkers. Frontiers in Human Neuroscience, 9(Art 18), (doi: 10.3389/fnhum.2015.00018)
Mercer, S. W. , Payne, R. A., Nicholl, B. I. and Morrison, J. (2015) Risk of intracranial haemorrhage linked to co-treatment with antidepressants and NSAIDs. British Medical Journal, 2015(351), h3745. (doi: 10.1136/bmj.h3745) (PMID:26173949)
Mercer, S. W. , Payne, R. A., Nicholl, B. N. and Morrison, J. (2015) Authors’ reply to Lewis and Bray. British Medical Journal, 2015(351), h4446. (doi: 10.1136/bmj.h4446) (PMID:26286087)
Nicholl, B. et al. (2015) Ethnic differences in the association between depression and chronic pain: cross sectional results from UK Biobank. BMC Family Practice, 16, 128. (doi: 10.1186/s12875-015-0343-5) (PMID:26445480) (PMCID:PMC4596418)
2014
Ul-Haq, Z. et al. (2014) Gender differences in the association between adiposity and probable major depression: a cross-sectional study of 140,564 UK Biobank participants. BMC Psychiatry, 14, p. 153. (doi: 10.1186/1471-244X-14-153)
Ul-Haq, Z. et al. (2014) Heaviness, health and happiness: a cross-sectional study of 163 066 UK Biobank participants. Journal of Epidemiology and Community Health, 68(4), pp. 340-348. (doi: 10.1136/jech-2013-203077) (PMID:24336235)
Sheikh, L., Nicholl, B.I. , Green, D.J., Bedson, J. and Peat, G. (2014) Osteoarthritis and the rule of halves. Osteoarthritis and Cartilage, 22(4), pp. 535-539. (doi: 10.1016/j.joca.2014.02.006)
Nicholl, B. I. et al. (2014) Chronic multisite pain in major depression and bipolar disorder: cross-sectional study of 149,611 participants in UK Biobank. BMC Psychiatry, 14, 350. (doi: 10.1186/s12888-014-0350-4) (PMID:25490859) (PMCID:PMC4297369)
2013
Clarson, L.E., Nicholl, B.I. , Bishop, A., Edwards, J., Daniel, R. and Mallen, C. (2013) Should there be a Quality and Outcomes Framework domain for osteoarthritis? A cross-sectional survey in general practice. Quality in Primary Care, 21(2), pp. 97-103.
Clarson, L.E., Nicholl, B.I. , Bishop, A., Edwards, J.J., Daniel, R. and Mallen, C.D. (2013) Monitoring osteoarthritis: a cross-sectional survey in general practice. Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders, 6, pp. 85-91. (doi: 10.4137/CMAMD.S12606)
Nicholl, B. , McBeth, J. and Mallen, C. (2013) Widespread musculoskeletal pain. In: Burton, C. (ed.) ABC of Medically Explained Symptoms. John Wiley & Sons: Chichester, UK, pp. 40-42. ISBN 9781119967255
Smith, D. et al. (2013) Prevalence and characteristics of probable major depression and bipolar disorder within UK Biobank: cross-sectional study of 172,751 participants. PLoS ONE, 8(11), e75362. (doi: 10.1371/journal.pone.0075362) (PMID:24282498) (PMCID:PMC3839907)
2011
Jones, G.T., Nicholl, B.I. , McBeth, J., Davies, K.A., Morriss, R.K., Dickens, C. and Macfarlane, G.J. (2011) Role of road traffic accidents and other traumatic events in the onset of chronic widespread pain: results from a population-based prospective study. Arthritis Care and Research, 63(5), pp. 696-701. (doi: 10.1002/acr.20417)
Nicholl, B.I. et al. (2011) Association of HTR2A polymorphisms with chronic widespread pain and the extent of musculoskeletal pain: results from two population-based cohorts. Arthritis and Rheumatism, 63(3), pp. 810-818. (doi: 10.1002/art.30185)
2010
McBeth, J., Nicholl, B.I. , Cordingley, L., Davies, K.A. and Macfarlane, G.J. (2010) Chronic widespread pain predicts physical inactivity: results from the prospective EPIFUND study. European Journal of Pain, 14(9), pp. 972-979. (doi: 10.1016/j.ejpain.2010.03.005)
Macfarlane, T.V., McBeth, J., Jones, G.T., Nicholl, B. and Macfarlane, G.J. (2010) Whether the weather influences pain? Results from the EpiFunD study in North West England. Rheumatology, 49(8), pp. 1513-1520. (doi: 10.1093/rheumatology/keq099)
Holliday, K.L., Macfarlane, G.J., Nicholl, B.I. , Creed, F., Thomson, W. and McBeth, J. (2010) Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study. Journal of Psychosomatic Research, 68(5), pp. 469-474. (doi: 10.1016/j.jpsychores.2010.01.024)
Holliday, K.L., Nicholl, B.I. , Macfarlane, G.J., Thomson, W., Davies, K.A. and McBeth, J. (2010) Genetic variation in the hypothalamic-pituitary-adrenal stress axis influences susceptibility to musculoskeletal pain: results from the EPIFUND study. Annals of the Rheumatic Diseases, 69(3), pp. 556-560. (doi: 10.1136/ard.2009.116137)
Nicholl, B.I. et al. (2010) No evidence for a role of the catechol-O-methyltransferase pain sensitivity haplotypes in chronic widespread pain. Annals of the Rheumatic Diseases, 69(11), pp. 2009-2012. (doi: 10.1136/ard.2009.126086)
2009
Davies, K.A., Silman, A.J., Macfarlane, G.J., Nicholl, B.I. , Dickens, C., Morriss, R., Ray, D. and McBeth, J. (2009) The association between neighbourhood socio-economic status and the onset of chronic widespread pain: results from the EPIFUND study. European Journal of Pain, 13(6), pp. 635-640. (doi: 10.1016/j.ejpain.2008.07.003)
Jones, E.A., McBeth, J., Nicholl, B.>i.> , Morriss, R.K., Dickens, C., Jones, G.T. and Macfarlane, G.J. (2009) What characterizes persons who do not report musculoskeletal pain? Results from a 4-year population-based longitudinal study (the Epifund study). Journal of Rheumatology, 36(5), pp. 1071-1077. (doi: 10.3899/jrheum.080541)
Nicholl, B.I. , Macfarlane, G.J., Davies, K.A., Morriss, R., Dickens, C. and McBeth, J. (2009) Premorbid psychosocial factors are associated with poor health-related quality of life in subjects with new onset of chronic widespread pain: results from the EPIFUND study. Pain, 141(1-2), pp. 119-126. (doi: 10.1016/j.pain.2008.10.022)
Holliday, K.L., Nicholl, B.I. , Macfarlane, G.J., Thomson, W., Davies, K.A. and McBeth, J. (2009) Do genetic predictors of pain sensitivity associate with persistent widespread pain? Molecular Pain, 5(56), (doi: 10.1186/1744-8069-5-56)
2008
Davies, K.A., Macfarlane, G.J., Nicholl, B.I. , Dickens, C., Morriss, R., Ray, D. and McBeth, J. (2008) Restorative sleep predicts the resolution of chronic widespread pain: results from the EPIFUND study. Rheumatology, 47(12), pp. 1809-1813. (doi: 10.1093/rheumatology/ken389)
Nicholl, B.I. , Halder, S.L., Macfarlane, G.J., Thompson, D.G., O’Brien, S., Musleh, M. and McBeth, J. (2008) Psychosocial risk markers for new onset irritable bowel syndrome: results of a large prospective population-based study. Pain, 137(1), pp. 147-155. (doi: 10.1016/j.pain.2007.08.029)
Limer, K.L., Nicholl, B.I. , Thomson, W. and McBeth, J. (2008) Exploring the genetic susceptibility of chronic widespread pain: the tender points in genetic association studies. Rheumatology, 47(5), pp. 572-577. (doi: 10.1093/rheumatology/ken027)
2007
Gupta, A., Silman, A.J., Ray, D., Morriss, R., Dickens, C., MacFarlane, G.J., Chiu, Y.H., Nicholl, B.I. and McBeth, J. (2007) The role of psychosocial factors in predicting the onset of chronic widespread pain: results from a prospective population-based study. Rheumatology, 46(4), pp. 666-671. (doi: 10.1093/rheumatology/kel363)
Articles
Pacitti, C. , Cairns, D. , Ward, L. and Nicholl, B. I. (2024) Investigating pain-related medication use and contribution to polypharmacy in adults with intellectual disabilities: a systematic review. BMC Medicine, 22, 565. (doi: 10.1186/s12916-024-03770-9)
Krauth, S. J. et al. (2024) Association of latent class analysis-derived multimorbidity clusters with adverse health outcomes in patients with multiple long-term conditions: comparative results across three UK cohorts. EClinicalMedicine, 74, 102703. (doi: 10.1016/j.eclinm.2024.102703)
Politis, M., Crawford, L. , Jani, B. D. , Nicholl, B. I. , Lewsey, J. , McAllister, D. A. , Mair, F. S. and Hanlon, P. (2024) An observational analysis of frailty in combination with loneliness or social isolation and their association with socioeconomic deprivation, hospitalisation and mortality among UK Biobank participants. Scientific Reports, 14, 7258. (doi: 10.1038/s41598-024-57366-7)
Erhahiemen, P. , O'Donnell, C. A. , Gallacher, K. and Nicholl, B. I. (2024) A systematic review of the experience of treatment burden of digital health for military personnel in primary healthcare. Health Open Research, 6(9), (doi: 10.12688/healthopenres.13599.1)
Mair, F. S. et al. (2024) Developing SysteMatic: prevention, precision and equity by design for people living with multiple long-term conditions. Journal of Multimorbidity and Comorbidity, 14, pp. 1-9. (doi: 10.1177/26335565241272682)
Foster, H. M.E. , Gill, J. M.R. , Mair, F. S. , Celis-Morales, C. A. , Jani, B. D. , Nicholl, B. I. , Lee, D. and O'Donnell, C. A. (2023) Social connection and mortality in UK Biobank: a prospective cohort analysis. BMC Medicine, 21, 384. (doi: 10.1186/s12916-023-03055-7) (PMID:37946218) (PMCID:PMC10637015)
Jani, B. D. , Sullivan, M. K. , Hanlon, P. , Nicholl, B. I. , Lees, J. S. , Brown, L., MacDonald, S. , Mark, P. B. , Mair, F. S. and Sullivan, F. M. (2023) Personalised lung cancer risk stratification and lung cancer screening: do general practice electronic medical records have a role? British Journal of Cancer, (doi: 10.1038/s41416-023-02467-9) (PMID:37880510) (Early Online Publication)
Rughani, G., Nilsen, T. I.L., Wood, K., Mair, F. S. , Hartvigsen, J., Mork, P. J. and Nicholl, B. I. (2023) The selfBACK artificial intelligence-based smartphone app can improve low back pain outcome even in patients with high levels of depression or stress. European Journal of Pain, 27(5), pp. 568-579. (doi: 10.1002/ejp.2080) (PMID:36680381)
Morton, F. R. , Jani, B. D. , Mair, F. S. , McLoone, P. , Canning, J., Macdonald, S. , McQueenie, R., Siebert, S. and Nicholl, B. I. (2023) Association between risk, duration and cause of hospitalisations in people with rheumatoid arthritis and multimorbidity in the UK Biobank and Scottish Early Rheumatoid Arthritis (SERA) cohorts: longitudinal observational study. Seminars in Arthritis and Rheumatism, 58, 152130. (doi: 10.1016/j.semarthrit.2022.152130) (PMID:36459724)
Hastie, C. E. , Foster, H. M.E. , Jani, B. D. , O'Donnell, C. A. , Ho, F. K., Pell, J. P. , Sattar, N. , Katikireddi, S. V. , Mair, F. S. and Nicholl, B. I. (2023) Chronic pain and COVID-19 hospitalisation and mortality: a UK Biobank cohort study. Pain, 164(1), pp. 84-90. (doi: 10.1097/j.pain.0000000000002663) (PMID:35452027) (PMCID:PMC9756431)
McLoone, P. , Jani, B. D. , Siebert, S. , Morton, F. R. , Canning, J., Macdonald, S. , Mair, F. S. and Nicholl, B. I. (2023) Classification of long-term condition patterns in rheumatoid arthritis and associations with adverse health events: a UK Biobank cohort study. Journal of Multimorbidity and Comorbidity, 13, p. 26335565221148616. (doi: 10.1177/26335565221148616) (PMID:36798088) (PMCID:PMC9926377)
Nguyen, T. N. et al. (2023) Multimorbidity and blood pressure control in patients attending primary care in Canada. Journal of Primary Care and Community Health, 14, pp. 1-9. (doi: 10.1177/21501319231215025) (PMID:38097504) (PMCID:PMC10725138)
Svendsen, M. J., Nicholl, B. I. , Mair, F. S. , Wood, K., Rasmussen, C. D. N. and Stochkendahl, M. J. (2022) One size does not fit all: participants’ experiences of the selfBACK app to support self-management of low back pain—a qualitative interview study. Chiropractic and Manual Therapies, 30, 41. (doi: 10.1186/s12998-022-00452-2) (PMID:36192724) (PMCID:PMC9531397)
Canning, J., Siebert, S. , Jani, B. , Harding-Edgar, L., Kempe, I., Mair, F. S. and Nicholl, B. I. (2022) Examining the relationship between rheumatoid arthritis, multimorbidity and adverse health-related outcomes: a systematic review. Arthritis Care and Research, 74(9), pp. 1500-1512. (doi: 10.1002/acr.24587) (PMID:33650196)
Hanlon, P. , Lewsey, J. , Quint, J. K., Jani, B. D. , Nicholl, B. I. , McAllister, D. A. and Mair, F. S. (2022) Frailty in COPD: an analysis of prevalence and clinical impact using UK Biobank. BMJ Open Respiratory Research, 9, e001314. (doi: 10.1136/bmjresp-2022-001314) (PMID:35787523) (PMCID:PMC9255399)
Foster, H. M.E. et al. (2022) The association between a lifestyle score, socioeconomic status, and COVID-19 outcomes within the UK Biobank cohort. BMC Infectious Diseases, 22, 273. (doi: 10.1186/s12879-022-07132-9) (PMID:35351028) (PMCID:PMC8964028)
Hanlon, P. , Jani, B. D. , Nicholl, B. , Lewsey, J. , McAllister, D. A. and Mair, F. S. (2022) Associations between multimorbidity and adverse health outcomes in UK Biobank and the SAIL Databank: a comparison of longitudinal cohort studies. PLoS Medicine, 19(3), e1003931. (doi: 10.1371/journal.pmed.1003931) (PMID:35255092) (PMCID:PMC8901063)
Øverås, C. K., Nilsen, T. I.L., Nicholl, B. I. , Rughani, G., Wood, K., Søgaard, K., Mair, F. S. and Hartvigsen, J. (2022) Multimorbidity and co-occurring musculoskeletal pain do not modify the effect of the selfBACK app on low back pain-related disability. BMC Medicine, 10, 53. (doi: 10.1186/s12916-022-02237-z) (PMID:35130898) (PMCID:PMC8822859)
Hanlon, P. , Morton, F. , Siebert, S. , Jani, B. D. , Nicholl, B. I. , Lewsey, J. , McAllister, D. and Mair, F. S. (2022) Frailty in rheumatoid arthritis and its relationship with disease activity, hospitalisation and mortality: a longitudinal analysis of the Scottish Early Rheumatoid Arthritis cohort and UK Biobank. RMD Open, 8(1), e002111. (doi: 10.1136/rmdopen-2021-002111) (PMID:35292529) (PMCID:PMC8928366)
Svendsen, M. J. et al. (2022) Using intervention mapping to develop a decision support system–based smartphone app (selfBACK) to support self-management of nonspecific low back pain: development and usability study. Journal of Medical Internet Research, 24(1), e26555. (doi: 10.2196/26555) (PMID:35072645) (PMCID:PMC8822424)
Corcoran, N. M.E. , Mair, F. S. , Nicholl, B. , Macdonald, S. and Jani, B. D. (2022) Long-term conditions, multimorbidity and colorectal cancer risk in the UK Biobank cohort. Journal of Multimorbidity and Comorbidity, 12, p. 26335565221110123. (doi: 10.1177/26335565221110123) (PMID:36132374) (PMCID:PMC9483970)
Sullivan, M. K. et al. (2021) Hospitalisation events in people with chronic kidney disease as a component of multimorbidity: parallel cohort studies in research and routine care settings. BMC Medicine, 19, 278. (doi: 10.1186/s12916-021-02147-6)
Sullivan, M. K. et al. (2021) Multimorbidity and the risk of major adverse kidney events: findings from the UK Biobank cohort. Clinical Kidney Journal, 14(11), pp. 2409-2419. (doi: 10.1093/ckj/sfab079) (PMCID:PMC8573008)
Jani, B. D. et al. (2021) Family history of diabetes and risk of SARS-COV-2 in UK Biobank: a prospective cohort study. Endocrinology, Diabetes and Metabolism, 4(4), e00283. (doi: 10.1002/edm2.283) (PMID:34505416) (PMCID:PMC8420405)
Sandal, L. F. et al. (2021) Effectiveness of app-delivered, tailored self-management support for adults with lower back pain–related disability. JAMA Internal Medicine, 181(10), pp. 1288-1296. (doi: 10.1001/jamainternmed.2021.4097) (PMID:34338710) (PMCID:PMC8329791)
Hanlon, P. , Jani, B. D. , Butterly, E., Nicholl, B. , Lewsey, J. , McAllister, D. A. and Mair, F. S. (2021) An analysis of frailty and multimorbidity in 20,566 UK Biobank participants with type 2 diabetes. Communications Medicine, 1, 28. (doi: 10.1038/s43856-021-00029-9) (PMID:35602215) (PMCID:PMC9053176)
Mutambudzi, M. et al. (2021) Occupation and risk of severe COVID-19: prospective cohort study of 120 075 UK Biobank participants. Occupational and Environmental Medicine, 78(5), pp. 307-314. (doi: 10.1136/oemed-2020-106731) (PMID:33298533)
Johnston, K. J.A. et al. (2021) Sex-stratified genome-wide association study of multisite chronic pain in UK Biobank. PLoS Genetics, 17(4), e1009428. (doi: 10.1371/journal.pgen.1009428) (PMID:33830993) (PMCID:PMC8031124)
Jani, B. D. , McQueenie, R., Nicholl, B. I. , Field, R. , Hanlon, P. , Gallacher, K. I. , Mair, F. S. and Lewsey, J. (2021) Association between patterns of alcohol consumption (beverage type, frequency and consumption with food) and risk of adverse health outcomes: a prospective cohort study. BMC Medicine, 19, 8. (doi: 10.1186/s12916-020-01878-2) (PMID:33430840) (PMCID:PMC7802201)
Marley, J., Nicholl, B. I. , Macdonald, S. , Mair, F. S. and Jani, B. D. (2021) Associations between long-term conditions and upper gastrointestinal cancer incidence: a prospective population-based cohort of UK Biobank participants. Journal of Multimorbidity and Comorbidity, 11, 2633556521. (doi: 10.1177/26335565211056136) (PMID:34820338) (PMCID:PMC8606912)
McQueenie, R., Jani, B. D. , Siebert, S. , McCowan, C. , Macdonald, S. , Mair, F. S. and Nicholl, B. I. (2021) Prevalence of chronic pain in LTCs and multimorbidity: a cross-sectional study using UK Biobank. Journal of Multimorbidity and Comorbidity, 11, p. 26335565211005870. (doi: 10.1177/26335565211005870)
Svendsen, M. J., Wood, K., Kyle, J., Cooper, K., Rasmussen, C. D. N., Sandal, L. F., Stochkendahl, M. J., Mair, F. S. and Nicholl, B. I. (2020) Barriers and facilitators to patient uptake and utilisation of digital interventions for the self-management of low back pain: a systematic review of qualitative studies. BMJ Open, 10(12), e038800. (doi: 10.1136/bmjopen-2020-038800) (PMID:33310794) (PMCID:PMC7735096)
Petermann-Rocha, F. et al. (2020) Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank. BMC Medicine, 18, 355. (doi: 10.1186/s12916-020-01822-4) (PMID:33167965) (PMCID:PMC7652674)
Chiang, J. I., Furler, J., Mair, F. , Jani, B. D. , Nicholl, B. I. , Thuraisingam, S. and Manski-Nankervis, J.-A. (2020) Associations between multimorbidity and glycaemia (HbA1c) in people with type 2 diabetes: cross-sectional study in Australian general practice. BMJ Open, 10(11), e039625. (doi: 10.1136/bmjopen-2020-039625) (PMID:33243798) (PMCID:PMC7692835)
Chiang, J. I., Manski-Nankervis, J.-A., Thuraisingam, S., Jenkins, A., O'Neal, D., Mair, F. S. , Jani, B. D. , Nicholl, B. I. and Furler, J. (2020) Multimorbidity, glycaemic variability and time in target range in people with type 2 diabetes: a baseline analysis of the GP-OSMOTIC trial. Diabetes Research and Clinical Practice, 169, 108451. (doi: 10.1016/j.diabres.2020.108451) (PMID:32949650)
McQueenie, R., Nicholl, B. I. , Jani, B. D. , Canning, J., Macdonald, S. , McCowan, C. , Neary, J. , Browne, S. , Mair, F. S. and Siebert, S. (2020) Patterns of multimorbidity and their effects on adverse outcomes in rheumatoid arthritis: a study of 5658 UK Biobank participants. BMJ Open, 10(11), e038829. (doi: 10.1136/bmjopen-2020-038829) (PMID:33234629) (PMCID:PMC7684828)
Rasmussen, C. D. N., Svendsen, M. J., Wood, K., Nicholl, B. I. , Mair, F. S. , Sandal, L. F., Mork, P. J., Søgaard, K., Bach, K. and Stochkendahl, M. J. (2020) App-delivered self-management intervention trial selfBACK for people with low back pain: protocol for implementation and process evaluation. JMIR Research Protocols, 9(10), e20308. (doi: 10.2196/20308) (PMID:33118959) (PMCID:PMC7661240)
McQueenie, R. et al. (2020) Multimorbidity, polypharmacy, and COVID-19 infection within the UK Biobank cohort. PLoS ONE, 15(8), e0238091. (doi: 10.1371/journal.pone.0238091) (PMID:32817712) (PMCID:PMC7440632)
Alslamah, T., Nicholl, B. , AlslailI, F. Y., Harris, L., Melville, C. A. and Kinnear, D. (2020) Cultural adaptation of self-management of type 2 diabetes in Saudi Arabia (qualitative study). PLoS ONE, 15(7), e0232904. (doi: 10.1371/journal.pone.0232904) (PMID:32722666) (PMCID:PMC7386581)
Niedzwiedz, C. L. et al. (2020) Ethnic and socioeconomic differences in SARS-CoV-2 infection: prospective cohort study using UK Biobank. BMC Medicine, 18, 160. (doi: 10.1186/s12916-020-01640-8) (PMID:32466757) (PMCID:PMC7255908)
Chiang, J. I. et al. (2020) Multimorbidity, mortality, and HbA1c in type 2 diabetes: a cohort study with UK and Taiwanese cohorts. PLoS Medicine, 17(5), e1003094. (doi: 10.1371/journal.pmed.1003094)
Al Slamah, T., Nicholl, B. I. , Alslail, F. Y., Harris, L., Kinnear, D. and Melville, C. A. (2020) Correlates of type 2 diabetes and glycaemic control in adults in Saudi Arabia a secondary data analysis of the Saudi health interview survey. BMC Public Health, 20, 515. (doi: 10.1186/s12889-020-08597-6) (PMID:32303201) (PMCID:PMC7164173)
Hanlon, P. et al. (2020) Assessing risks of polypharmacy involving medications with anticholinergic properties. Annals of Family Medicine, 18(2), pp. 148-155. (doi: 10.1370/afm.2501) (PMID:32152019) (PMCID:PMC7062487)
Canning, J., Siebert, S. , Jani, B. D. , Mair, F. S. and Nicholl, B. I. (2020) Examining the relationship between rheumatoid arthritis, multimorbidity and adverse health-related outcomes: a systematic review protocol. Journal of Comorbidity, 10, pp. 1-5. (doi: 10.1177/2235042X20906657)
Mair, F. S. , Foster, H. M.E. and Nicholl, B. I. (2020) Multimorbidity and the COVID-19 pandemic – an urgent call to action. Journal of Comorbidity, 10, pp. 1-2. (doi: 10.1177/2235042X20961676) (PMID:33117721) (PMCID:PMC7573706)
Sandal, L. F. et al. (2019) An app-delivered self-management program for people with low back pain: protocol for the selfBACK randomised controlled trial. JMIR Research Protocols, 8(12), e14720. (doi: 10.2196/14720) (PMID:31793897) (PMCID:PMC6918200)
Johnston, K. J.A., Adams, M. J., Nicholl, B. I. , Ward, J. , Strawbridge, R. , McIntosh, A., Smith, D. J. and Bailey, M. E.S. (2019) Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5. Translational Psychiatry, 9, 310. (doi: 10.1038/s41398-019-0613-4) (PMID:31748543) (PMCID:PMC6868167)
Gallacher, K. I. , Jani, B. D. , Hanlon, P. , Nicholl, B. I. and Mair, F. S. (2019) Multimorbidity in stroke. Stroke, 50(7), pp. 1919-1926. (doi: 10.1161/STROKEAHA.118.020376) (PMID:31233391)
Johnston, K. J.A., Adams, M. J., Nicholl, B. I. , Ward, J. , Strawbridge, R. , Ferguson, A., McIntosh, A., Bailey, M. E.S. and Smith, D. J. (2019) Genome-wide association study of multisite chronic pain in UK Biobank. PLoS Genetics, 15(6), e1008164. (doi: 10.1371/journal.pgen.1008164) (PMID:31194737) (PMCID:PMC6592570)
Jani, B. D. , Hanlon, P. , Nicholl, B. I. , McQueenie, R., Gallacher, K. I. , Lee, D. and Mair, F. S. (2019) Relationship between multimorbidity, demographic factors and mortality: findings from the UK Biobank Cohort. BMC Medicine, 17, 74. (doi: 10.1186/s12916-019-1305-x) (PMID:30967141) (PMCID:PMC6456941)
Bach, K., Marling, C., Mork, P. J., Aamodt, A., Mair, F. S. and Nicholl, B. I. (2019) Design of a clinician dashboard to facilitate co-decision making in the management of non-specific low back pain. Journal of Intelligent Information Systems, 52(2), pp. 269-284. (doi: 10.1007/s10844-018-0539-y)
Chiang, J. I., Jani, B. D. , Mair, F. S. , Nicholl, B. I. , Furler, J., O’Neal, D., Jenkins, A., Condron, P. and Manski-Nankervis, J.-A. (2018) Associations between multimorbidity, all-cause mortality and glycaemia in people with type 2 diabetes: a systematic review. PLoS ONE, 13(12), e0209585. (doi: 10.1371/journal.pone.0209585) (PMID:30586451) (PMCID:PMC6306267)
Foster, H. M.E. , Celis-Morales, C. A. , Nicholl, B. I. , Petermann, F., Pell, J. P. , Gill, J. M.R. , O'Donnell, C. A. and Mair, F. S. (2018) The effect of socioeconomic deprivation on the association between an extended measurement of unhealthy lifestyle factors and health outcomes: a prospective analysis of the UK Biobank cohort. Lancet Public Health, 3(12), e576-e585. (doi: 10.1016/S2468-2667(18)30200-7) (PMID:30467019)
Kigozi, J. et al. (2018) Cost‐utility analysis of routine anxiety and depression screening in patients consulting for osteoarthritis: results from a clinical, randomized controlled trial. Arthritis Care and Research, 70(12), pp. 1787-1794. (doi: 10.1002/acr.23568) (PMID:29609205)
Jani, B. D. , Nicholl, B. I. , McQueenie, R., Connelly, D. T., Hanlon, P. , Gallacher, K. I. , Lee, D. and Mair, F. S. (2018) Multimorbidity and co-morbidity in atrial fibrillation and effects on survival: findings from UK Biobank cohort. Europace, 20, f329-f336. (doi: 10.1093/europace/eux322) (PMID:29112751) (PMCID:PMC6277149)
Hanlon, P. , Nicholl, B. I. , Jani, B. D. , Lee, D. , McQueenie, R. and Mair, F. S. (2018) Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective analysis of 493,737 UK Biobank participants. Lancet Public Health, 3(7), e323-e332. (doi: 10.1016/S2468-2667(18)30091-4) (PMID:29908859) (PMCID:PMC6028743)
Chiang, J. I., Furler, J., Mair, F. S. , Jani, B. , Nicholl, B. I. , Jenkins, A., Condron, P., O’Neal, D. and Manski-Nankervis, J.-A. (2018) Impact of multimorbidity count on all-cause mortality and glycaemic outcomes in people with type 2 diabetes: a systematic review protocol. BMJ Open, 8(4), e021100. (doi: 10.1136/bmjopen-2017-021100) (PMID:29626050)
Gallacher, K. I. , McQueenie, R., Nicholl, B. , Jani, B. D. , Lee, D. and Mair, F. S. (2018) Risk factors and mortality associated with multimorbidity in people with stroke or transient ischaemic attack: a study of 8,751 UK Biobank participants. Journal of Comorbidity, 8(1), pp. 1-8. (doi: 10.15256/joc.2018.8.129)
Hanlon, P. , Nicholl, B. I. , Jani, B. D. , McQueenie, R., Lee, D. , Gallacher, K. I. and Mair, F. S. (2018) Examining patterns of multimorbidity, polypharmacy and risk of adverse drug reactions in chronic obstructive pulmonary disease: a cross-sectional UK Biobank study. BMJ Open, 8(1), e018404. (doi: 10.1136/bmjopen-2017-018404) (PMID:29332840) (PMCID:PMC5781016)
Al Slamah, T., Nicholl, B. I. , Alslail, F. Y. and Melville, C. A. (2017) Self-management of type 2 diabetes in Gulf Cooperation Council countries: a systematic review. PLoS ONE, 12(12), e0189160. (doi: 10.1371/journal.pone.0189160) (PMID:29232697) (PMCID:PMC5726716)
Nicholl, B. et al. (2017) Digital support interventions for the self-management of low back pain: a systematic review. Journal of Medical Internet Research, 19(5), e179. (doi: 10.2196/jmir.7290) (PMID:28550009)
Mallen, C. D. et al. (2017) The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care. PLoS Medicine, 14(4), e1002273. (doi: 10.1371/journal.pmed.1002273) (PMID:28399129) (PMCID:PMC5388468)
Mundal, I., Bjørngaard, J. H., Nilsen, T. I.L., Nicholl, B. I. , Gråwe, R. W. and Fors, E. A. (2016) Long-term changes in musculoskeletal pain sites in the general population: the HUNT study. Journal of Pain, 17(11), pp. 1246-1256. (doi: 10.1016/j.jpain.2016.08.006) (PMID:27578444)
McIntosh, A. M. et al. (2016) Genetic and environmental risk for chronic pain and the contribution of risk variants for major depressive disorder: a family-based mixed-model analysis. PLoS Medicine, 13(8), e1002090. (doi: 10.1371/journal.pmed.1002090) (PMID:27529168) (PMCID:PMC4987025)
Clarson, L.E., Nicholl, B.I. , Bishop, A., Daniel, R. and Mallen, C.D. (2016) Discussing prognosis with patients with osteoarthritis: a cross-sectional survey in general practice. Clinical Rheumatology, 35(4), pp. 1011-1017. (doi: 10.1007/s10067-015-3094-8) (PMID:26474771)
Martin, D. J. et al. (2016) Cardiometabolic disease and features of depression and bipolar disorder: population-based, cross-sectional study. British Journal of Psychiatry, 208(4), pp. 343-351. (doi: 10.1192/bjp.bp.114.157784) (PMID:26795427)
Smith, D.J. et al. (2016) Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci. Molecular Psychiatry, 21(6), pp. 749-757. (doi: 10.1038/mp.2016.49) (PMID:27067015)
Cullen, B. et al. (2015) Cognitive function and lifetime features of depression and bipolar disorder in a large population sample: Cross-sectional study of 143,828 UK Biobank participants. European Psychiatry, 30(8), pp. 950-958. (doi: 10.1016/j.eurpsy.2015.08.006) (PMID:26647871)
Jani, B. D. , McLean, G., Nicholl, B. I. , Barry, S. J.E. , Sattar, N. , Mair, F. S. and Cavanagh, J. (2015) Risk assessment and predicting outcomes in patients with depressive symptoms: a review of potential role of peripheral blood based biomarkers. Frontiers in Human Neuroscience, 9(Art 18), (doi: 10.3389/fnhum.2015.00018)
Mercer, S. W. , Payne, R. A., Nicholl, B. I. and Morrison, J. (2015) Risk of intracranial haemorrhage linked to co-treatment with antidepressants and NSAIDs. British Medical Journal, 2015(351), h3745. (doi: 10.1136/bmj.h3745) (PMID:26173949)
Mercer, S. W. , Payne, R. A., Nicholl, B. N. and Morrison, J. (2015) Authors’ reply to Lewis and Bray. British Medical Journal, 2015(351), h4446. (doi: 10.1136/bmj.h4446) (PMID:26286087)
Nicholl, B. et al. (2015) Ethnic differences in the association between depression and chronic pain: cross sectional results from UK Biobank. BMC Family Practice, 16, 128. (doi: 10.1186/s12875-015-0343-5) (PMID:26445480) (PMCID:PMC4596418)
Ul-Haq, Z. et al. (2014) Gender differences in the association between adiposity and probable major depression: a cross-sectional study of 140,564 UK Biobank participants. BMC Psychiatry, 14, p. 153. (doi: 10.1186/1471-244X-14-153)
Ul-Haq, Z. et al. (2014) Heaviness, health and happiness: a cross-sectional study of 163 066 UK Biobank participants. Journal of Epidemiology and Community Health, 68(4), pp. 340-348. (doi: 10.1136/jech-2013-203077) (PMID:24336235)
Sheikh, L., Nicholl, B.I. , Green, D.J., Bedson, J. and Peat, G. (2014) Osteoarthritis and the rule of halves. Osteoarthritis and Cartilage, 22(4), pp. 535-539. (doi: 10.1016/j.joca.2014.02.006)
Nicholl, B. I. et al. (2014) Chronic multisite pain in major depression and bipolar disorder: cross-sectional study of 149,611 participants in UK Biobank. BMC Psychiatry, 14, 350. (doi: 10.1186/s12888-014-0350-4) (PMID:25490859) (PMCID:PMC4297369)
Clarson, L.E., Nicholl, B.I. , Bishop, A., Edwards, J., Daniel, R. and Mallen, C. (2013) Should there be a Quality and Outcomes Framework domain for osteoarthritis? A cross-sectional survey in general practice. Quality in Primary Care, 21(2), pp. 97-103.
Clarson, L.E., Nicholl, B.I. , Bishop, A., Edwards, J.J., Daniel, R. and Mallen, C.D. (2013) Monitoring osteoarthritis: a cross-sectional survey in general practice. Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders, 6, pp. 85-91. (doi: 10.4137/CMAMD.S12606)
Smith, D. et al. (2013) Prevalence and characteristics of probable major depression and bipolar disorder within UK Biobank: cross-sectional study of 172,751 participants. PLoS ONE, 8(11), e75362. (doi: 10.1371/journal.pone.0075362) (PMID:24282498) (PMCID:PMC3839907)
Jones, G.T., Nicholl, B.I. , McBeth, J., Davies, K.A., Morriss, R.K., Dickens, C. and Macfarlane, G.J. (2011) Role of road traffic accidents and other traumatic events in the onset of chronic widespread pain: results from a population-based prospective study. Arthritis Care and Research, 63(5), pp. 696-701. (doi: 10.1002/acr.20417)
Nicholl, B.I. et al. (2011) Association of HTR2A polymorphisms with chronic widespread pain and the extent of musculoskeletal pain: results from two population-based cohorts. Arthritis and Rheumatism, 63(3), pp. 810-818. (doi: 10.1002/art.30185)
McBeth, J., Nicholl, B.I. , Cordingley, L., Davies, K.A. and Macfarlane, G.J. (2010) Chronic widespread pain predicts physical inactivity: results from the prospective EPIFUND study. European Journal of Pain, 14(9), pp. 972-979. (doi: 10.1016/j.ejpain.2010.03.005)
Macfarlane, T.V., McBeth, J., Jones, G.T., Nicholl, B. and Macfarlane, G.J. (2010) Whether the weather influences pain? Results from the EpiFunD study in North West England. Rheumatology, 49(8), pp. 1513-1520. (doi: 10.1093/rheumatology/keq099)
Holliday, K.L., Macfarlane, G.J., Nicholl, B.I. , Creed, F., Thomson, W. and McBeth, J. (2010) Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study. Journal of Psychosomatic Research, 68(5), pp. 469-474. (doi: 10.1016/j.jpsychores.2010.01.024)
Holliday, K.L., Nicholl, B.I. , Macfarlane, G.J., Thomson, W., Davies, K.A. and McBeth, J. (2010) Genetic variation in the hypothalamic-pituitary-adrenal stress axis influences susceptibility to musculoskeletal pain: results from the EPIFUND study. Annals of the Rheumatic Diseases, 69(3), pp. 556-560. (doi: 10.1136/ard.2009.116137)
Nicholl, B.I. et al. (2010) No evidence for a role of the catechol-O-methyltransferase pain sensitivity haplotypes in chronic widespread pain. Annals of the Rheumatic Diseases, 69(11), pp. 2009-2012. (doi: 10.1136/ard.2009.126086)
Davies, K.A., Silman, A.J., Macfarlane, G.J., Nicholl, B.I. , Dickens, C., Morriss, R., Ray, D. and McBeth, J. (2009) The association between neighbourhood socio-economic status and the onset of chronic widespread pain: results from the EPIFUND study. European Journal of Pain, 13(6), pp. 635-640. (doi: 10.1016/j.ejpain.2008.07.003)
Jones, E.A., McBeth, J., Nicholl, B.>i.> , Morriss, R.K., Dickens, C., Jones, G.T. and Macfarlane, G.J. (2009) What characterizes persons who do not report musculoskeletal pain? Results from a 4-year population-based longitudinal study (the Epifund study). Journal of Rheumatology, 36(5), pp. 1071-1077. (doi: 10.3899/jrheum.080541)
Nicholl, B.I. , Macfarlane, G.J., Davies, K.A., Morriss, R., Dickens, C. and McBeth, J. (2009) Premorbid psychosocial factors are associated with poor health-related quality of life in subjects with new onset of chronic widespread pain: results from the EPIFUND study. Pain, 141(1-2), pp. 119-126. (doi: 10.1016/j.pain.2008.10.022)
Holliday, K.L., Nicholl, B.I. , Macfarlane, G.J., Thomson, W., Davies, K.A. and McBeth, J. (2009) Do genetic predictors of pain sensitivity associate with persistent widespread pain? Molecular Pain, 5(56), (doi: 10.1186/1744-8069-5-56)
Davies, K.A., Macfarlane, G.J., Nicholl, B.I. , Dickens, C., Morriss, R., Ray, D. and McBeth, J. (2008) Restorative sleep predicts the resolution of chronic widespread pain: results from the EPIFUND study. Rheumatology, 47(12), pp. 1809-1813. (doi: 10.1093/rheumatology/ken389)
Nicholl, B.I. , Halder, S.L., Macfarlane, G.J., Thompson, D.G., O’Brien, S., Musleh, M. and McBeth, J. (2008) Psychosocial risk markers for new onset irritable bowel syndrome: results of a large prospective population-based study. Pain, 137(1), pp. 147-155. (doi: 10.1016/j.pain.2007.08.029)
Limer, K.L., Nicholl, B.I. , Thomson, W. and McBeth, J. (2008) Exploring the genetic susceptibility of chronic widespread pain: the tender points in genetic association studies. Rheumatology, 47(5), pp. 572-577. (doi: 10.1093/rheumatology/ken027)
Gupta, A., Silman, A.J., Ray, D., Morriss, R., Dickens, C., MacFarlane, G.J., Chiu, Y.H., Nicholl, B.I. and McBeth, J. (2007) The role of psychosocial factors in predicting the onset of chronic widespread pain: results from a prospective population-based study. Rheumatology, 46(4), pp. 666-671. (doi: 10.1093/rheumatology/kel363)
Book Sections
Nicholl, B. , McBeth, J. and Mallen, C. (2013) Widespread musculoskeletal pain. In: Burton, C. (ed.) ABC of Medically Explained Symptoms. John Wiley & Sons: Chichester, UK, pp. 40-42. ISBN 9781119967255
Research Reports or Papers
Jani, B. et al. (2019) Evaluation of New Models of Primary Care in Scotland: Lanarkshire Case Study. Project Report. Scottish School of Primary Care.
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Chronic pain in the context of multimorbidity
Versus Arthritis
2018 - 2021
- Relationship of Multi-morbidity with cancer incidence and outcomes in a large population cohort: Use of Data Sciences Methodology
British Medical Association
2018 - 2019
- Multimorbidity in UK Biobank
Chief Scientist Office
2016 - 2017
- Patterns of co-morbidity in stroke and associations with hospital admission and mortality - an observational study
The Carnegie Trust for the Universities of Scotland
2016 - 2016
- SELFBACK
European Commission
2016 - 2020
- Evaluation of new models of care in NHS Ayrshire and Arran
Scottish Government
2015 - 2018
- Evaluation of new Models of Care MSK
Scottish Government
2015 - 2018
- New Models of Care NHS Lanarkshire
Scottish Government
2015 - 2018
Supervision
- Erhahiemen, Paul
Optimisation of patient outcomes by identifying the priorities and barriers to the adaptation and implementation of digital health and Artificial Intelligence (AI) in the management of chronic diseases in primary care - Opoku-pare, George Addo
Psoriatic Arthritis, comorbidity and treatment burden: Personalised risk stratification based on risk of adverse clinical outcomes. - Pacitti, Christine
Investigating pain in adults with learning disabilities
Teaching
Postgraduate teaching
MSc in Primary Care http://www.gla.ac.uk/mscprimarycare
- MSc in Primary Care programme coordinator
- Course coordinator, "Epidemiology, evidence and statistics"
- Joint course coordinator, "Research methods"
Research datasets
2021
Johnston, K., Ward, J., Ray, P. R., Adams, M. J., McIntosh, A. M., Smith, B., Strawbridge, R. , Price, T. J., Smith, D. J., Nicholl, B. and Bailey, M. (2021) Sex-Stratified Genome-Wide Association Study of Multisite Chronic Pain in UK Biobank. [Data Collection]
2019
Johnston, K., Adams, M. J., Nicholl, B. , Ward, J., Strawbridge, R. , Ferguson, A., McIntosh, A. M., Bailey, M. and Smith, D. (2019) Genome-wide association summary statistics for a genome-wide association study of multisite chronic pain. [Data Collection]